CN109567785A - A kind of quantum magneticencephalogram system and method based on magnetic shielding cylinder - Google Patents
A kind of quantum magneticencephalogram system and method based on magnetic shielding cylinder Download PDFInfo
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- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/242—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents
- A61B5/245—Detecting biomagnetic fields, e.g. magnetic fields produced by bioelectric currents specially adapted for magnetoencephalographic [MEG] signals
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Abstract
The invention discloses a kind of quantum magneticencephalogram system and method based on magnetic shielding cylinder, including quantum detector and array system, environmental magnetic field shielding harness, quantum detector control system, data collection and transmission and stimulation and feedback system, the quantum detector and array system are connect with the quantum detector control system two-way signaling, the quantum detector control system, the stimulation are connect with feedback system with the data collection and transmission signal, and environmental magnetic field shielding harness is provided with outside the quantum detector and array system.The technical effect of the invention is that operation cost is low；The detection array that can flexibly change matches individual's head profile, improves detection efficient, while can be generalized to the detection of all ages and classes stage efficient signal；Extraneoas loss of the brain magnetic signal on space length is avoided, absolute signal strengths are improved；The screened room that traditional magneticencephalogram indispensability is replaced with magnetic shielding cylinder, significantly improves the performance of magnetic screen while saving cost.
Description
Technical field
Invention is related to magneticencephalogram technical field, specially a kind of quantum magneticencephalogram system and method based on magnetic shielding cylinder.
Background technique
Magneticencephalogram is a kind of brain intrinsic nerve member activity to be inferred by measuring the magnetic field that generates outside head of neuroelectricity
Noninvasive cerebral function imaging method.Magneticencephalogram has the temporal resolution and higher spatial resolution of superelevation, in nerve, spirit
There is important role in the lesion diagnosis and Cognitive Neuroscience research of disease.
The signal in brain magnetic field is very faint, the about 0.1-1pT outside scalp.The magneticencephalogram of Current commercial utilizes Superconducting Quantum
Core device of the interferometer (superconducting quantum interference device, SQUID) as detection of magnetic field
Part, but SQUID needs work under the conditions of the superconduction that liquid helium maintains, while needing to build the shielding external world between huge magnetic screen
The interference in magnetic field causes the manufacture of magneticencephalogram and maintenance cost very expensive.Simultaneously as maintain ultralow temperature Dewar tank vacuum every
Thermosphere limits detector and scalp is in close contact, and causes brain magnetic signal to be decayed on space length seriously, signal is further cut
It is weak.
In recent years, the quantum detector of lower light and atomic interaction, also referred to as atom magnetometer are manipulated based on quantum
Or atom magnetometer, also referred to as it is proved to be able to replace SQUID detection brain magnetic signal.Atom magnetometer utilizes alkali metal atom
As external magnetic field generates deflection after polarization in circularly polarized light, and then absorption or the progress of linear polarization angle are carried out partially to the intensity of light
Turn, to reflect the size in magnetic field.Currently, atom magnetometer detector can be accomplished to minimize, theoretical limit sensitivity
Higher than SQUIID.Simultaneously as not needing liquid helium maintenance and Dewar tank, the manufacture of detector and maintenance cost can drop significantly
It is low, and detector can be close to scalp, significantly improve the intensity of brain magnetic signal.
Current magneticencephalogram system still remains following disadvantage:
1, existing business magneticencephalogram utilizes superconductive device, needs to consume liquid helium, at high cost.
2, for existing business magneticencephalogram because Dewar tank thickness limits detector and scalp is in close contact, signal is weak.
3, Current commercial magneticencephalogram can not match individual's head profile, cause because detection array is fixed on Dewar internal layer
Signal further decreases, and when being especially the lesser subject in the heads such as children, the loss of signal is serious, needs specially to purchase one again
The equipment of a small-sized helmet for children.
4, current magneticencephalogram cost is too high, while needing to build expensive screened room, with high costs.
Summary of the invention
Invention is designed to provide a kind of quantum magneticencephalogram system based on magnetic shielding cylinder, to solve above-mentioned background technique
The problem of middle proposition.
To achieve the above object, invention provides the following technical solutions: a kind of quantum magneticencephalogram system based on magnetic shielding cylinder,
Including quantum detector and array system, environmental magnetic field shielding harness, quantum detector control system, data collection and analysis system
System and stimulation and feedback system, the quantum detector and array system and the quantum detector control system two-way signaling connect
It connecing, the quantum detector control system, the stimulation are connect with feedback system with the data collection and transmission signal,
Environmental magnetic field shielding harness is provided with outside the quantum detector and array system.
Preferably, the quantum detector and array system include the detection helmet, are offered on the detection helmet several
The slot of a array arrangement is equipped with quantum detector on the slot, and the quantum detector is to manipulate technology based on quantum
Atom magnetometer.
Preferably, the quantum detector is the primary element of brain detection of magnetic field, and the quantum detector is by alkali metal gas
Room, light source, heating sheet, optical element, photodetector and modulation coil composition.
Optical element main function used is being polarized for laser, such as the analyzing of circular polarization, linear polarization and laser.
Quantum detector used, generally based on no spin-exchange relaxation (Spin-exchange relaxation
Free) the atom magnetometer of principle, but also it is not excluded for other types；Alkali metal gas chamber used is generally potassium, caesium, rubidium or three
Both any mixing atomic gas in person.
Preferably, the environmental magnetic field shielding harness includes magnetic shielding cylinder and slides bed, the magnetic shielding cylinder without magnetic mechanical
Main shielding external magnetic field, high permeability material and high conductive material, and every two are successively respectively adopted in adjacent materials from inside to outside
It is filled between layer using non-magnetic material isolation, magnetic shielding cylinder two sides installation detachable end, it is same in the magnetic shielding cylinder to feel at ease
Equipped with coil rack, three dimensional coils are installed on the coil rack.
Preferably, the quantum detector control system is acquisition and control assembly, the quantum detector control system
Including atomic spin operational module and light and temperature electric control module.
Preferably, the data collection and transmission is acquisition control computer, the data collection and transmission
Including data analog-to-digital conversion collection plate, Data acquisition and storage software, real-time cerebral function imaging module and automation source positioning mould
Block.
Preferably, the stimulation and feedback system mainly include auditory stimulation module, visual stimulus module, haptic stimulus mould
Block and key feedback module.
Compared with prior art, advantageous effect of the invention is:
1, should quantum magneticencephalogram system based on magnetic shielding cylinder, the atom magnetometer used without consuming liquid helium, operation at
This significant decrease.
2, should quantum magneticencephalogram system based on magnetic shielding cylinder, using the detection helmet by the end of probe and head of atom magnetometer
Skin is in close contact, and avoids the extraneoas loss of brain magnetic signal, improves absolute signal strengths.
3, should quantum magneticencephalogram system based on magnetic shielding cylinder, design and a set of be made of the detection helmet and atom magnetometer
Quantum detector and array system, the detection array that can flexibly change match individual's head profile, improve detection efficient；Together
When can be generalized to all ages and classes stage efficient signal detection.
4, the quantum magneticencephalogram system based on magnetic shielding cylinder, including passive magnetic screen module and active magnetic shroud module are somebody's turn to do.
Using a kind of environmental magnetic field shielding harness of completely new cylindrical cartridge composition, height is successively respectively adopted in adjacent materials from inside to outside
Permeability magnetic material and high conductive material, and using non-magnetic material isolation filling between every two layers, the installation of magnetic shielding cylinder two sides is removable
The end cap unloaded is equipped with coil rack in magnetic shielding cylinder with one heart, is equipped with three dimensional coils on coil rack, substitutes traditional shielding
Room, subject are scanned using prone position, significantly reduce the cost of magnetic screen, while improving the performance of magnetic screen.
Detailed description of the invention
Fig. 1 is a kind of quantum magneticencephalogram system structure diagram based on magnetic shielding cylinder；
Fig. 2 is a kind of quantum magneticencephalogram system composition schematic diagram based on magnetic shielding cylinder.
Fig. 3 is the quantum detector and array system schematic diagram of a kind of quantum magneticencephalogram system based on magnetic shielding cylinder.
In figure: 1- quantum detector and array system；2- environmental magnetic field shielding harness；3- quantum detector control system；
4- data collection and transmission；5- stimulation and feedback system；6- key feedback system.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.It is based on
Embodiment in the present invention, it is obtained by those of ordinary skill in the art without making creative efforts every other
Embodiment shall fall within the protection scope of the present invention.
Shown in please referring to Fig.1 to Fig.3, invention provides a kind of technical solution: a kind of quantum magneticencephalogram based on magnetic shielding cylinder
System, including quantum detector and array system 1, environmental magnetic field shielding harness 2, quantum detector control system 3, data acquisition
It is with analysis system 4 and stimulation and feedback system 5, the quantum detector and array system 1 and quantum detector control
3 two-way signalings of uniting connection, the quantum detector control system 3, described stimulate acquire and divide with feedback system 5 and the data
The connection of 4 signal of analysis system, the quantum detector and array system 1 are provided with environmental magnetic field shielding harness 2 outside.
Preferably, the quantum detector and array system 1 include the detection helmet, are offered on the detection helmet several
The slot of a array arrangement is equipped with quantum detector on the slot, and the quantum detector is to manipulate technology based on quantum
Atom magnetometer.
Preferably, the quantum detector is the primary element of brain detection of magnetic field, and the quantum detector is by alkali metal gas
Room, light source, heating sheet, optical element, photodetector and modulation coil composition.
Optical element main function used is being polarized for laser, such as the analyzing of circular polarization, linear polarization and laser.
Atom magnetometer used, generally based on no spin-exchange relaxation (Spin-exchange relaxation
Free) type magnetometer, but also it is not excluded for other types；Alkali metal gas chamber used is generally any in potassium, caesium, rubidium or three
The mixing atomic gas of the two.
Preferably, the environmental magnetic field shielding harness 2 includes magnetic shielding cylinder and slides bed, the magnetic shielding cylinder without magnetic mechanical
Main shielding external magnetic field, high permeability material and high conductive material, and every two are successively respectively adopted in adjacent materials from inside to outside
It is filled between layer using non-magnetic material isolation, magnetic shielding cylinder two sides installation detachable end, it is same in the magnetic shielding cylinder to feel at ease
Equipped with coil rack, three dimensional coils are installed on the coil rack.
Preferably, the quantum detector control system 3 is acquisition and control assembly, the quantum detector control system
3 include atomic spin operational module and light and temperature electric control module.
Preferably, the data collection and transmission 4 is acquisition control computer, the data collection and transmission
4 include data analog-to-digital conversion collection plate, Data acquisition and storage software, real-time cerebral function imaging module and automation source positioning mould
Block.
Preferably, the stimulation and feedback system 5 mainly include auditory stimulation module, visual stimulus module, haptic stimulus
Module and key feedback module.
Advantageous effect of the invention is: being somebody's turn to do the quantum magneticencephalogram system based on magnetic shielding cylinder, the atom magnetometer used is not necessarily to
Liquid helium is consumed, operation cost significantly reduces.The quantum magneticencephalogram system based on magnetic shielding cylinder, using the detection helmet by nonmagnetic atom
The end of probe and scalp counted by force are in close contact, and avoid the extraneoas loss of brain magnetic signal, improve absolute signal strengths.It should be based on magnetic cup
The quantum magneticencephalogram system of cylinder is covered, a set of quantum detector and array system being made of the detection helmet and atom magnetometer is designed
1, the detection array that can flexibly change matches individual's head profile, improves detection efficient；It can be generalized to all ages and classes simultaneously
The detection of stage efficient signal.The quantum magneticencephalogram system based on magnetic shielding cylinder uses a kind of completely new magnetic shielding cylinder composition
Environmental magnetic field shielding harness 2, including multi-layer shield material passive screening and three dimensional coils active magnetic screen, substitute traditional screen
Room is covered, subject is scanned using prone position, significantly reduces the cost of magnetic screen, while improving the performance of magnetic screen.
Obviously, various changes and modifications can be made to the invention without departing from essence of the invention by those skilled in the art
Mind and range.In this way, if these modifications and changes of the present invention belongs to the range of the claims in the present invention and its equivalent technologies
Within, then the present invention is also intended to include these modifications and variations.
Claims (7)
1. a kind of quantum magneticencephalogram system based on magnetic shielding cylinder, it is characterised in that: including quantum detector and array system
(1), environmental magnetic field shielding harness (2), quantum detector control system (3), data collection and transmission (4) and stimulation with it is anti-
Feedback system (5), the quantum detector and array system (1) are connect with quantum detector control system (3) two-way signaling,
The quantum detector control system (3), the stimulation are believed with feedback system (5) and the data collection and transmission (4)
Number connection is provided with environmental magnetic field shielding harness (2) outside the quantum detector and array system (1).
2. a kind of quantum magneticencephalogram system based on magnetic shielding cylinder as described in claim 1, it is characterised in that: the quantum is visited
It surveys device and array system (1) includes the detection helmet, the slot of several arrays arrangement is offered on the detection helmet, it is described to insert
Quantum detector is installed, the quantum detector is the atom magnetometer technology manipulated based on quantum on slot.
3. a kind of quantum magneticencephalogram system based on magnetic shielding cylinder as claimed in claim 2, it is characterised in that: the quantum is visited
The primary element that device is brain detection of magnetic field is surveyed, the quantum detector is by alkali metal gas chamber, light source, heating sheet, optical element, light
Electric explorer and modulation coil composition.
4. a kind of quantum magneticencephalogram system based on magnetic shielding cylinder as described in claim 1, it is characterised in that: the environment magnetic
Field shielding harness (2) includes magnetic shielding cylinder and slides bed without magnetic mechanical, and the magnetic shielding cylinder mainly shields external magnetic field, by introversion
High permeability material and high conductive material is successively respectively adopted in outer adjacent materials, and is filled out between every two layers using non-magnetic material isolation
It fills, detachable end is installed in magnetic shielding cylinder two sides, is equipped with coil rack, the coil rack with one heart in the magnetic shielding cylinder
On three-dimensional bucking coil is installed.
5. a kind of quantum magneticencephalogram system based on magnetic shielding cylinder as described in claim 1, it is characterised in that: the quantum is visited
Surveying device control system (3) is acquisition and control assembly, and the quantum detector control system (3) includes atomic spin operational module
And light and temperature electric control module.
6. a kind of quantum magneticencephalogram system based on magnetic shielding cylinder as described in claim 1, it is characterised in that: the data are adopted
Integrate with analysis system (4) as acquisition control computer, the data collection and transmission (4) includes the acquisition of data analog-to-digital conversion
Plate, Data acquisition and storage software, real-time cerebral function imaging module and automation source locating module.
7. a kind of quantum magneticencephalogram system based on magnetic shielding cylinder as described in claim 1, it is characterised in that: the stimulation with
Feedback system (5) mainly includes auditory stimulation module, visual stimulus module, haptic stimulus module and key feedback module.
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| CN201811478606.0A CN109567785A (en) | 2018-12-05 | 2018-12-05 | A kind of quantum magneticencephalogram system and method based on magnetic shielding cylinder |
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Cited By (7)
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| CN110477898A (en) * | 2019-08-28 | 2019-11-22 | 张海军 | A kind of wearable medical monitoring device and system based on weak magnetic detection |
| CN111983526A (en) * | 2020-08-24 | 2020-11-24 | 清华大学 | Atomic magnetometer and magnetic field imaging system |
| CN113040775A (en) * | 2021-03-22 | 2021-06-29 | 漫迪医疗仪器（上海）有限公司 | Biomagnetic detection device, biomagnetic detection method, storage medium and control terminal |
| CN113827246A (en) * | 2021-11-25 | 2021-12-24 | 北京航空航天大学杭州创新研究院 | Magnetoencephalography data acquisition and analysis method and system |
| CN113918008A (en) * | 2021-08-30 | 2022-01-11 | 北京大学 | Brain-computer interface system based on source space brain magnetic signal decoding and application method |
| CN113967019A (en) * | 2021-05-28 | 2022-01-25 | 北京昆迈医疗科技有限公司 | Magnetoencephalography system and method of operating magnetoencephalography system |
| WO2023197441A1 (en) * | 2022-04-15 | 2023-10-19 | 北京昆迈医疗科技有限公司 | Opm array rapid optical scanning and positioning method based on spatial labeling points |
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| Publication number | Priority date | Publication date | Assignee | Title |
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Effective date of registration: 20220424 Address after: Room 103, building 1, zone B, Yiyuan cultural and creative base, No. 80, xingshikou Road, Haidian District, Beijing 100093 Applicant after: Beijing kunmai Medical Technology Co.,Ltd. Address before: 100089 No. 5, the Summer Palace Road, Beijing, Haidian District Applicant before: Peking University |
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Application publication date: 20190405 |