CN109691997A - The detection method in brain detector for magnetic field and brain magnetic field - Google Patents
The detection method in brain detector for magnetic field and brain magnetic field Download PDFInfo
- Publication number
- CN109691997A CN109691997A CN201910033198.6A CN201910033198A CN109691997A CN 109691997 A CN109691997 A CN 109691997A CN 201910033198 A CN201910033198 A CN 201910033198A CN 109691997 A CN109691997 A CN 109691997A
- Authority
- CN
- China
- Prior art keywords
- magnetic field
- gradient
- electric current
- brain
- environmental
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 210000004556 brain Anatomy 0.000 title claims abstract description 77
- 238000001514 detection method Methods 0.000 title claims abstract description 37
- 230000007613 environmental effect Effects 0.000 claims abstract description 59
- 239000000523 sample Substances 0.000 claims abstract description 46
- 238000012545 processing Methods 0.000 claims abstract description 43
- 238000000034 method Methods 0.000 claims description 7
- 230000003287 optical effect Effects 0.000 claims description 5
- 238000005086 pumping Methods 0.000 claims description 3
- 229910052783 alkali metal Inorganic materials 0.000 claims description 2
- 150000001340 alkali metals Chemical group 0.000 claims description 2
- 238000010586 diagram Methods 0.000 description 18
- 230000000875 corresponding effect Effects 0.000 description 5
- 241000238366 Cephalopoda Species 0.000 description 3
- 229910052792 caesium Inorganic materials 0.000 description 3
- 210000002569 neuron Anatomy 0.000 description 3
- 230000002596 correlated effect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000002689 soil Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000036760 body temperature Effects 0.000 description 1
- TVFDJXOCXUVLDH-UHFFFAOYSA-N caesium atom Chemical compound [Cs] TVFDJXOCXUVLDH-UHFFFAOYSA-N 0.000 description 1
- 230000002490 cerebral effect Effects 0.000 description 1
- 238000012938 design process Methods 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000005672 electromagnetic field Effects 0.000 description 1
- 230000005358 geomagnetic field Effects 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 230000035945 sensitivity Effects 0.000 description 1
- 238000012360 testing method Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/05—Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/0033—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room
- A61B5/004—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part
- A61B5/0042—Features or image-related aspects of imaging apparatus classified in A61B5/00, e.g. for MRI, optical tomography or impedance tomography apparatus; arrangements of imaging apparatus in a room adapted for image acquisition of a particular organ or body part for the brain
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R1/00—Details of instruments or arrangements of the types included in groups G01R5/00 - G01R13/00 and G01R31/00
- G01R1/02—General constructional details
- G01R1/18—Screening arrangements against electric or magnetic fields, e.g. against earth's field
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
- G01R33/022—Measuring gradient
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
- G01R33/032—Measuring direction or magnitude of magnetic fields or magnetic flux using magneto-optic devices, e.g. Faraday or Cotton-Mouton effect
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01R—MEASURING ELECTRIC VARIABLES; MEASURING MAGNETIC VARIABLES
- G01R33/00—Arrangements or instruments for measuring magnetic variables
- G01R33/02—Measuring direction or magnitude of magnetic fields or magnetic flux
- G01R33/10—Plotting field distribution ; Measuring field distribution
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2562/00—Details of sensors; Constructional details of sensor housings or probes; Accessories for sensors
- A61B2562/18—Shielding or protection of sensors from environmental influences, e.g. protection from mechanical damage
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B2576/00—Medical imaging apparatus involving image processing or analysis
- A61B2576/02—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part
- A61B2576/026—Medical imaging apparatus involving image processing or analysis specially adapted for a particular organ or body part for the brain
Abstract
The invention discloses a kind of brain detector for magnetic field and brain magnetic field detection methods, the brain detector for magnetic field includes: screen unit, probe in magnetometer, processing unit, for receiving the human brain magnetic field detected and environmental magnetic field, second control signal is exported after exporting first control signal, and/or processing First-order Gradient magnetic field after processing zeroth order steady magnetic field；And control unit, it receives first and/or second control signal and exports the first electric current and/or the second electric current to screen unit with shielding environment magnetic field, by the above-mentioned means, to improve the detection accuracy in brain magnetic field.
Description
Technical field
The present invention relates to Technology of Precision Measurement fields, more particularly to the detection in a kind of brain detector for magnetic field and brain magnetic field
Method.
Background technique
Cerebral neuron activity generates electric current and then generates brain magnetic field, this magnetic field is very faint, generally 10-15(fly spy
This draws magnitude) tesla or so, it could be recorded with special magnetic field measurement instrument.Magneticencephalogram (MEI) detection in the prior art
Instrument is the variation for carrying out to record brain magnetic field signal by using low-temperature superconducting technology (SQUID) in real time, reconstructs medical diagnosis figure
Picture.But since geomagnetic field intensity is generally 10-6Tesla only disappears so needing for MEI to be placed on an electromagnetic-field shielding chamber
Magnetic field signal in addition to can just detect winged tesla's magnitude of brain wave generation behind earth's magnetic field and ambient noise magnetic field.
Magneticencephalogram (MEI) detector around patients head by placing multiple low temperature squids
(SQUID), brain magnetic wave caused by the electric current generated as neuron activity is detected.Complete equipment must be placed in detection process
To shield various background magnetic field noises in electromagnetic shielding chamber, it is big that there are equipment volumes, safeguards and maintenance is complicated and is directed to difference
The problem of accuracy of detection difference when patient's head dummy and human motion.
Summary of the invention
The invention mainly solves the technical problem of providing a kind of brain detector for magnetic field and the detection method in brain magnetic field, with
Improve detection accuracy.
In order to solve the above technical problems, one technical scheme adopted by the invention is that:
A kind of brain detector for magnetic field is provided, comprising:
Screen unit, for generating armoured magnetic field；And
Magnetometer, comprising:
Probe, for detecting human brain magnetic field and environmental magnetic field；
Processing unit is connected with the probe, for receiving the human brain magnetic field detected and environmental magnetic field from the probe
And to exporting first control signal after the steady magnetic field processing in the environmental magnetic field, and/or to according to the environmental magnetic field and
In gradient magnetic processing after export second control signal；And
Control unit is connect with the processing unit and the screen unit, described in receiving from the processing unit
First and/or second control signal and the first electric current and/or the second electric current are exported according to described first and/or second control signal
To the screen unit, the screen unit generates armoured magnetic field according to first electric current and/or second electric current to shield
State environmental magnetic field in covert.
In order to solve the above technical problems, another technical solution used in the present invention is:
A kind of detection method in brain magnetic field is provided, comprising:
Detect human brain magnetic field and environmental magnetic field；
According to the human brain magnetic field and environmental magnetic field detected to defeated after the zeroth order steady magnetic field processing in the environmental magnetic field
First control signal out, and/or to according in the environmental magnetic field First-order Gradient magnetic field processing after export second control signal；
And
Receive described first and/or second control signal and according to described first and/or second control signal output first
Electric current and/or the second electric current are to generate the armoured magnetic field for shielding the environmental magnetic field.
The beneficial effects of the present invention are: being in contrast to the prior art, the present invention passes through probe detection brain magnetic field and ring
Border magnetic field exports first control signal after handling through the processing unit the steady magnetic field in the environmental magnetic field, and/or to institute
State environmental magnetic field and in gradient magnetic processing after export second control signal；And it is connect by control unit from the processing unit
It receives described first and/or second control signal and the first electric current and/or the is exported according to described first and/or second control signal
Two electric currents to screen unit, the screen unit according to first electric current and/or second electric current generate armoured magnetic field with
The environmental magnetic field is shielded, the detection accuracy in brain magnetic field is improved.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of brain detector for magnetic field of the present invention；
Fig. 2 is the structural schematic diagram of brain detector for magnetic field first embodiment of the present invention；
Fig. 3 is the detection process schematic diagram of brain detector for magnetic field first embodiment of the present invention；
Fig. 4 is the structural schematic diagram of the first screen unit of the invention；
Fig. 5 is the structural schematic diagram of the first shielding area of the invention；
Fig. 6 is the structural schematic diagram of brain detector for magnetic field second embodiment of the present invention；
Fig. 7 is structural schematic diagram of the secondary shielding unit with support plate of the present invention；
Fig. 8 is the overlooking structure diagram of gradient coil of the present invention；
Fig. 9 is the schematic perspective view of gradient coil of the present invention；
Figure 10 is the detection process schematic diagram of brain detector for magnetic field second embodiment of the present invention；
Figure 11 is the structural schematic diagram of brain detector for magnetic field 3rd embodiment of the present invention；
Figure 12 is the structural schematic diagram of third shielding area of the present invention；
Figure 13 is the flow diagram of magnetic field detection method of the present invention.
Specific embodiment
The present invention will be described in detail with reference to the accompanying drawings and examples.
Referring to Fig. 1, being the structural schematic diagram of brain detector for magnetic field of the present invention.The brain detector for magnetic field 100 wraps
It includes:
Screen unit 10, for generating armoured magnetic field；And
Magnetometer 20, comprising:
Probe 21, for detecting human brain magnetic field and environmental magnetic field；
Processing unit 22 is connect with the probe 21, for receiving the human brain magnetic field detected and ring from the probe 21
Border magnetic field and to first control signal is exported after the steady magnetic field processing in the environmental magnetic field, and/or to according to the environment
Magnetic field and in gradient magnetic processing after export second control signal；And
Control unit 23 is connect with the processing unit 22 and the screen unit 10, is used for from the processing unit 22
Receive described first and/or second control signal and according to described first and/or second control signal export the first electric current and/or
Second electric current gives the screen unit 10, and the screen unit 10 is generated according to first electric current and/or second electric current
Armoured magnetic field is to shield the environmental magnetic field.
Referring to Fig. 2, being the structural schematic diagram of brain detector for magnetic field first embodiment of the present invention.The brain magnetic field detection
Unit 100 includes:
First screen unit 11, for generating the first armoured magnetic field；
Magnetometer 20,
Probe 21, for detecting human brain magnetic field and environmental magnetic field；
Processing unit 22 is connect with the probe 21, for receiving the human brain magnetic field detected and ring from the probe 21
Border magnetic field and in the environmental magnetic field zeroth order steady magnetic field processing after export first control signal；
Control unit 23 is connect with the processing unit 22 and first screen unit 11, for single from the processing
Member 22 receives the first control signal and exports the first electric current to first screen unit according to the first control signal
11, first screen unit 11 generates the first armoured magnetic field according to first electric current to shield zero in the environmental magnetic field
Rank steady magnetic field.
Wherein, it is described probe 21 for alkali metal atom optical pumping pop one's head in, it is described probe 21 include at least one first probe and
At least three second probes, every one second probe is for detecting in the both direction vertical with the laser direction of the probe 21
Environmental magnetic field.
In conjunction with Fig. 3, the probe 21 includes three first probes, 211,212,213 and three second probes 214,215,
216.First probe 211~213 is set to human body head, can be attached at the head of human body to be checked, around setting, be used for
Human brain magnetic field and zeroth order steady magnetic field are detected, multiple first probes also can be used in other embodiments and be arranged in human body head
Near portion, to realize full brain covering.In the present embodiment, the magnetometer 20 uses Cs atom optical pumped magnetometer, by its Cs atom
Optical pumping probe is attached to the use of human body head surface, wherein caesium (Cs) steam works in body temperature, does not have to load in use in this way
The heart can burn patient, and the volume very little (5 cubic millimeters) of the probe 21 further shortens the probe 21 in this way and generates
The distance between the brain neuron in magnetic field can provide the detection sensitivity for flying special magnitude, and the optical pumped magnetometer is according to need
The frequency for the brain magnetic wave to be detected, adjustable working frequency and reception bandwidth.
Second probe 214~216 is arranged far from human body head, for detecting extraneous steady magnetic field.Wherein, described
The laser direction of two probes 214 is X-axis, detects the steady magnetic field By1 and Bz1 in Y-axis positive direction and Z axis positive direction, described the
The laser direction of two probes 215 is Y-axis, detects zeroth order steady magnetic field Bx1 and Bz2 in X-axis positive direction and Z axis negative direction, institute
The laser direction for stating the second probe 216 is Z axis, detects steady magnetic field Bx2 and By2 in X-axis negative direction and Y-axis negative direction.
Referring to Fig. 4, being the structural schematic diagram of the first screen unit of the invention.First screen unit 11 includes six
Planar coil 111~116, six planar coils 111~116 constitute a cube M.The processing unit 22 will be according to three
Six zeroth order steady magnetic fields of Bx1, Bx2, By1, By2, Bz1 and Bz2 that a second probe 214~216 detects calculate
It obtains six the first electric current I1, exports first control signal to described control unit 23, make described control unit 23 by institute
Six planar coils 111~116 that six the first electric current I1 are inputted respectively on corresponding direction are stated, so that six planar coils
111~116 generate six first armoured magnetic fields contrary with six zeroth order steady magnetic fields, steady to shield the zeroth order
Constant charge soil.
Specifically, according to the correlometer formula in magnetic field and electric current, by six zeroth order steady magnetic field Bx1, Bx2, By1,
By2, Bz1 and Bz2 are calculated the first electric current I1 that can generate magnetic field of corresponding size, respectively I1-x1, II-x2,
II-y1, II-y2, II-z1 and II-z2.As shown in figure 4, to the planar coil 111 be passed through along clockwise direction first
Electric current I1-y1, generation is contrary with the By1, and (direction of By1 is that Y-axis is square to equal-sized first armoured magnetic field By1 '
To the direction of By1 ' is Y-axis negative direction), the zeroth order steady magnetic field By1 is shielded.Edge is passed through to the planar coil 112
Conterclockwise first electric current I1-z1 generates, equal-sized first armoured magnetic field Bz1 ' (Bz1 contrary with the Bz1
Direction be Z axis positive direction, the direction of Bz1 ' is Z axis negative direction), the zeroth order steady magnetic field Bz1 is shielded.To described flat
Planar coil 113 is passed through the first electric current I1-x1 along clockwise direction, and generation is contrary with the Bx1, and equal-sized first
Armoured magnetic field Bx1 ' (direction of Bx1 is X-axis positive direction, and the direction of Bx1 ' is X-axis negative direction), by the zeroth order steady magnetic field
Bx1 shielding.It is passed through the first electric current I1-z2 in the counterclockwise direction to the planar coil 114, is generated and the direction Bz2 phase
Instead, equal-sized first armoured magnetic field Bz2 ' (direction of Bz2 is Z axis negative direction, and the direction of Bz2 ' is Z axis positive direction), with
The zeroth order steady magnetic field Bz2 is shielded.It is passed through the first electric current I1-x2 in the counterclockwise direction to the planar coil 115, is produced
Life is contrary with the Bx2, and (direction of Bx2 is X-axis negative direction, the side of Bx2 ' to equal-sized first armoured magnetic field Bx2 '
To for X-axis positive direction), the zeroth order steady magnetic field Bx2 is shielded.It is passed through in the counterclockwise direction to the planar coil 116
The first electric current I1-y2, generate contrary with the By2, (direction of By2 is Y by equal-sized first armoured magnetic field By2 '
Axis negative direction, the direction of By2 ' are Y-axis positive direction), the zeroth order steady magnetic field By2 is shielded.
The present embodiment by first screen unit 11 generate with the zeroth order steady magnetic field Bx1, Bx2, By1, By2,
Bz1 and Bz2 are equal in magnitude, contrary the first armoured magnetic field Bx1 ', Bx2 ', By1 ', By2 ', Bz1 ' and
Bz2 ', and then the zeroth order steady magnetic field in the external magnetic field is shielded, to reduce external magnetic field band during brain magnetic field detection
The influence come improves detection accuracy.Meanwhile six planar coils of first screen unit 11 are passed through corresponding described the
It is generated after one electric current I1, forms the first shielding area A as shown in Figure 5, the head of human body to be detected can be in first shielding
It is move freely in the A of region without influencing detection accuracy.
Referring to Fig. 6, being the structural schematic diagram of brain detector for magnetic field second embodiment of the present invention.The brain magnetic field detection
Unit 100 includes:
Secondary shielding unit 12, for generating secondary shielding magnetic field.
Magnetometer 20,
Probe 21, for detecting human brain magnetic field and environmental magnetic field；
Processing unit 22 is connect with the probe 21, for receiving the human brain magnetic field detected and ring from the probe 21
Border magnetic field and in the environmental magnetic field First-order Gradient magnetic field processing after export second control signal；
Control unit 23 is connect with the processing unit 22 and the secondary shielding unit 12, for single from the processing
Member 22 receives the second control signal and exports the second electric current to the secondary shielding unit according to the second control signal
12, the secondary shielding unit 12 generates the secondary shielding magnetic field according to second electric current, to shield the environmental magnetic field
In First-order Gradient magnetic field.
As shown in fig. 7, the secondary shielding unit 12 includes two groups of gradient coils 121 and 122, the secondary shielding unit
12 two groups of gradient coils can be respectively arranged on two support plate S1 and S2, so that two groups of gradient coils 121 and 122 can be with
It is oppositely arranged on the two sides of human body head.As shown in figure 8, by taking wherein gradient coil 121 described in one group as an example, the gradient coil
121 include the first gradient coil P1 of a circular ring shape and four the second gradient coil Q1 around the first gradient coil P1
~Q4.Be the perspective view of the gradient coil 121 in conjunction with Fig. 9, wherein plane a where the second gradient coil Q1~Q4 with
Plane b is vertical where the first gradient coil P1, and the second gradient coil Q1~Q4 is around the first gradient coil P1
One side L1 be along the arc-shaped around direction.In practical applications, by the opposite of the second gradient coil Q1~Q4
The side L2 be arranged as far as possible it is short so that the first gradient coil P1 and the second gradient coil Q1~Q4 can be produced on together
In one support plate (not shown).
Relative to the first embodiment, processing unit 22 described in the present embodiment is according to three second probes 214
~216 six zeroth order steady magnetic fields of Bx1, Bx2, By1, By2, Bz1 and the Bz2 detected and three second probes
Three First-order Gradient magnetic field G on X, Y, Z axis direction are calculated in 214~216 spatial position coordinatex, Gy, Gz, the place
Unit 22 is managed further according to the correlometer formula of gradient magnetic and electric current, by the three First-order Gradient magnetic field Gx、Gy、GzIt calculates
Three the second electric current I2 that magnetic field gradient of corresponding size can be generated out, export second control signal to described control unit
23, make described control unit 23 that three second electric current I2 are inputed to two groups of gradient coils 121 and 122 respectively, with
Two groups of gradient coils 121 and 122 are made to generate the three secondary shielding magnetic opposite with three First-order Gradient magnetic directions
, to shield the First-order Gradient magnetic field.
As shown in Figure 10, two groups of gradient coils 121 and 122 are oppositely arranged on the two sides of human body head, wherein described
Eight the second gradient coil Q1~Q8 in two groups of gradient coils 121 and 122 are for generating shielding X-axis and Y direction
The secondary shielding magnetic field in First-order Gradient magnetic field, two first gradients coil P1 and P2 in two groups of gradient coils are for generating
Shield the secondary shielding magnetic field in First-order Gradient magnetic field in Z-direction.
The present embodiment is generated and the First-order Gradient magnetic field G by the secondary shielding unit 12x、Gy、GzEqual in magnitude,
The contrary secondary shielding magnetic field, and then by the First-order Gradient magnetic field shielding in the external magnetic field, reduce brain magnetic field
External magnetic field bring influences in detection process, improves detection accuracy.Meanwhile two groups of gradient lines of the secondary shielding unit 12
Circle 121 and 122 forms secondary shielding region B after the corresponding second electric current I2 of input, and the head of human body to be detected can be
It is move freely in the secondary shielding region B without influencing detection accuracy.
Figure 11 is please referred to, is the structural schematic diagram of brain detector for magnetic field 3rd embodiment of the present invention.Relative to the present invention
Second embodiment (Fig. 6), the brain detector for magnetic field 100 further include the first screen unit 11, are connected with described control unit 23
It connects, for generating the first armoured magnetic field.
The processing unit 22 can receive the human brain magnetic field detected and environmental magnetic field and to described from the probe 21
First control signal is exported after zeroth order steady magnetic field processing in environmental magnetic field, and to according to the single order in the environmental magnetic field
Second control signal is exported after gradient magnetic processing；Described control unit 23 receives described first and from the processing unit 22
Two control signals export the first electric current I1 to first screen unit 11, first screen according to the first control signal
It covers unit 11 and first armoured magnetic field is generated to shield the zeroth order steady magnetic field in the environmental magnetic field according to the first electric current I1；
And the second electric current I2 is exported to the secondary shielding unit 12, the secondary shielding unit 12 according to the second control signal
Secondary shielding magnetic field is generated to shield the First-order Gradient magnetic field in the environmental magnetic field according to the second electric current I2, and then further
Improve the detection accuracy in brain magnetic field.
As shown in figure 12, the size of the planar coil in first screen unit 11, the number of turns are constituted by adjusting
And other correlated variables adjust the size for being formed by the first shielding area A, pass through to adjust and constitute the secondary shielding list
The size of the gradient coil in member 12, the number of turns and other correlated variables are formed by secondary shielding region B's to adjust
Size, to form a side length c for the third shielding area C of the cube of 40cm, to accommodate the head of human body to be measured, people to be detected
The head of body can be move freely without influencing detection accuracy in the third shielding area C.The third shielding area C is
The overlapping region of the first shielding area A and secondary shielding region B, not no external magnetic field in the third shielding area C
Interference, while magnetic field is interfered without redundant equipment, device bring, so that the testing result in brain magnetic field is more accurate.
In the present embodiment, the third shielding area C is the secondary shielding region B.In other embodiments, as long as
Meet in the finally formed third shielding area without external magnetic field, also interferes magnetic without redundant equipment, device bring
?.
Figure 13 is please referred to, is the flow diagram of brain magnetic field detection method of the present invention.The brain magnetic field detection method includes:
Step S1: detection human brain magnetic field and environmental magnetic field.
Specifically, detecting human brain magnetic field and environmental magnetic field in human body head；
Environmental magnetic field is being detected far from number of people body portion.
The environmental magnetic field includes zeroth order steady magnetic field and First-order Gradient magnetic field.
Step S2: according to the human brain magnetic field and environmental magnetic field detected to the zeroth order steady magnetic field in the environmental magnetic field at
First control signal is exported after reason, and/or to according to the second control of output after the First-order Gradient magnetic field processing in the environmental magnetic field
Signal processed.
Step S3: reception described first and/or second control signal are simultaneously defeated according to described first and/or second control signal
The first electric current and/or the second electric current are out to generate the armoured magnetic field for shielding the environmental magnetic field.Specifically, being controlled by described first
Signal processed exports the first electric current, and first electric current generates the first armoured magnetic field, steady to shield the zeroth order in the environmental magnetic field
Constant charge soil.
Wherein, the first armoured magnetic field of the first electric current generation includes:
First electric current is inputted into six planar coils, six planar coils constitute a cube, make described flat
Planar coil generates the first screen in X-axis positive direction and negative direction, Y-axis positive direction and negative direction and Z axis positive direction and negative direction
Cover magnetic field.
The second electric current is exported by the second control signal, second electric current generates secondary shielding magnetic field, with shielding
First-order Gradient magnetic field in the environmental magnetic field.
Second electric current generates secondary shielding magnetic field
Second electric current is inputted into two groups of gradient coils, two groups of gradient coils generate the ladder on X-axis, Y-axis and Z axis
Spend magnetic field, gradient coil described in every group include a circular ring shape first gradient coil and around the first gradient coil four
A second gradient coil, second gradient coil are set as on one side around the first gradient coil along the circular direction
Circular arc, plane where second gradient coil is vertical with the first gradient coil place plane；
Eight second gradient coils that second electric current inputs in two groups of gradient coils generate X-axis and Y-axis
Gradient magnetic on direction, second electric current input two first gradient coils in two groups of gradient coils and generate Z axis
Gradient magnetic on direction.
Wherein, first screen unit and the secondary shielding unit specifically work and design process, same to Fig. 1~figure
Associated description in 12, details are not described herein.
For the present invention by detecting zeroth order steady magnetic field and First-order Gradient magnetic field in environmental magnetic field, processing, which obtains, can generate phase
Answer the first electric current and the second electric current of big small magnetic field.By inputting the first electric current to planar coil, it is allowed to generate and the zeroth order
Steady magnetic field is equal in magnitude, contrary magnetic field, to shield the zeroth order steady magnetic field.By to gradient coil input second
Electric current is allowed to generate the magnetic field equal in magnitude, contrary with the First-order Gradient magnetic field, to shield the First-order Gradient magnetic
, and then improve the accuracy of the brain magnetic field detection device.
Mode the above is only the implementation of the present invention is not intended to limit the scope of the invention, all to utilize this
Equivalent structure or equivalent flow shift made by description of the invention and accompanying drawing content, it is relevant to be applied directly or indirectly in other
Technical field is included within the scope of the present invention.
Claims (10)
1. a kind of brain detector for magnetic field characterized by comprising
Screen unit, for generating armoured magnetic field；And
Magnetometer, comprising:
Probe, for detecting human brain magnetic field and environmental magnetic field；
Processing unit is connected with the probe, for receiving the human brain magnetic field that detects and environmental magnetic field and right from the probe
First control signal is exported after steady magnetic field processing in the environmental magnetic field, and/or to the gradient magnetic in the environmental magnetic field
Second control signal is exported after the processing of field；And
Control unit is connect with the processing unit and the screen unit, for receiving described first from the processing unit
And/or second control signal and the first electric current and/or the second electric current are exported to institute according to described first and/or second control signal
Screen unit is stated, the screen unit generates armoured magnetic field according to first electric current and/or second electric current to shield
State environmental magnetic field.
2. brain detector for magnetic field according to claim 1, which is characterized in that the probe is that alkali metal atom optical pumping is visited
Head, the probe include at least one first probe and at least three second probes；
At least one described first probe setting is in human body head, for detecting human brain magnetic field and environmental magnetic field, described at least three
A second pops one's head in is arranged far from human body head, and every one second probe is for detecting two vertical with the laser direction of the probe
Environmental magnetic field on direction.
3. brain detector for magnetic field according to claim 1, which is characterized in that the screen unit includes that the first shielding is single
Member, first screen unit include six planar coils, and it is single to the control that the processing unit exports first control signal
Member exports the first electric current to the planar coil to control described control unit, and the planar coil constitutes a cube to generate
The first armoured magnetic field in X-axis positive direction and negative direction, Y-axis positive direction and negative direction and Z axis positive direction and negative direction, with screen
State the zeroth order steady magnetic field in environmental magnetic field in covert.
4. brain detector for magnetic field according to claim 1, which is characterized in that the screen unit further includes secondary shielding
Unit, the secondary shielding unit include two groups of gradient coils, and the processing unit exports second control signal to the control
Unit exports the second electric current to the gradient coil to control described control unit, and the gradient coil generates secondary shielding magnetic
, to shield the First-order Gradient magnetic field in the environmental magnetic field.
5. brain detector for magnetic field according to claim 4, which is characterized in that two groups of gradients of the secondary shielding unit
Coil, is oppositely arranged on the two sides of human body head respectively, and gradient coil described in every group includes the first gradient coil of a circular ring shape
And four the second gradient coils around the first gradient coil, second gradient coil is around the first gradient line
Circle is where plane where the circular arc around direction, second gradient coil and the first gradient coil on one side
Plane is vertical；
Eight second gradient coils in two groups of gradient coils are used to generate the gradient magnetic in X-axis and Y direction,
Two first gradient coils in two groups of gradient coils are used to generate the gradient magnetic in Z-direction.
6. a kind of detection method in brain magnetic field characterized by comprising
Detect human brain magnetic field and environmental magnetic field；
According to the human brain magnetic field and environmental magnetic field detected to exporting the after the zeroth order steady magnetic field processing in the environmental magnetic field
One control signal, and/or to according in the environmental magnetic field First-order Gradient magnetic field processing after export second control signal；And
Receive described first and/or second control signal and according to described first and/or second control signal export the first electric current
And/or second electric current to generate the armoured magnetic field for shielding the environmental magnetic field.
7. brain magnetic field detection method according to claim 6, which is characterized in that the detection human brain magnetic field and environmental magnetic field
Include:
Human brain magnetic field and environmental magnetic field are detected in human body head；
Environmental magnetic field is being detected far from human body head.
8. brain magnetic field detection method according to claim 7, which comprises
The first electric current is exported by the first control signal, first electric current generates the first armoured magnetic field, described in shielding
Zeroth order steady magnetic field in environmental magnetic field；
First electric current generates the first armoured magnetic field
First electric current is inputted into six planar coils, six planar coils constitute a cube, make the planar line
Circle generates the first shielding magnetic in X-axis positive direction and negative direction, Y-axis positive direction and negative direction and Z axis positive direction and negative direction
?.
9. brain magnetic field detection method according to claim 8, which is characterized in that the described method includes:
The second electric current is exported by the second control signal, second electric current generates secondary shielding magnetic field, described in shielding
First-order Gradient magnetic field in environmental magnetic field.
10. brain magnetic field detection method according to claim 9, which is characterized in that second electric current generates secondary shielding
Magnetic field includes:
Second electric current is inputted into two groups of gradient coils, two groups of gradient coils generate the gradient magnetic on X-axis, Y-axis and Z axis
, gradient coil described in every group includes the first gradient coil of a circular ring shape and around four of the first gradient coil the
Two gradient coils, second gradient coil are set as the circle along the circular direction around the first gradient coil on one side
Arc, plane is vertical with plane where the first gradient coil where second gradient coil；
Eight second gradient coils that second electric current inputs in two groups of gradient coils generate X-axis and Y direction
On gradient magnetic, second electric current input two first gradient coils in two groups of gradient coils generate Z-direction
On gradient magnetic.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910033198.6A CN109691997A (en) | 2019-01-14 | 2019-01-14 | The detection method in brain detector for magnetic field and brain magnetic field |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201910033198.6A CN109691997A (en) | 2019-01-14 | 2019-01-14 | The detection method in brain detector for magnetic field and brain magnetic field |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109691997A true CN109691997A (en) | 2019-04-30 |
Family
ID=66233429
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201910033198.6A Pending CN109691997A (en) | 2019-01-14 | 2019-01-14 | The detection method in brain detector for magnetic field and brain magnetic field |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109691997A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113183707A (en) * | 2021-05-21 | 2021-07-30 | 辽宁工业大学 | Design method and system of whole-vehicle active suspension self-adaptive fixed-period sampling controller |
| CN113967019A (en) * | 2021-05-28 | 2022-01-25 | 北京昆迈医疗科技有限公司 | Magnetoencephalography system and method of operating magnetoencephalography system |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5339811A (en) * | 1991-11-06 | 1994-08-23 | Mitsui Mining & Smelting Co., Ltd. | Magnetoencephalograph |
| US20040006267A1 (en) * | 2003-07-29 | 2004-01-08 | Buchanan D. Scott | Magnetically shielded room with internal active magnetic field cancellation, and its use |
| JP2005294537A (en) * | 2004-03-31 | 2005-10-20 | Takenaka Komuten Co Ltd | Panel-type coil, uniform magnetic field generator, gradient magnetic field generator and magnetic field canceling device |
| JP2008078529A (en) * | 2006-09-25 | 2008-04-03 | Mti:Kk | Magnetic shielding room of internal active magnetically shielded system |
| WO2010029725A1 (en) * | 2008-09-10 | 2010-03-18 | 株式会社竹中工務店 | Magnetic shield system and magnetic shield method |
| CN105022005A (en) * | 2014-04-23 | 2015-11-04 | 中国科学院上海微系统与信息技术研究所 | SQUID magnetic sensor measuring sensitivity enhancement method, device and system |
| CN106859629A (en) * | 2017-01-18 | 2017-06-20 | 上海理工大学 | Ambient noise weakens system and method in magneticencephalogram detection |
-
2019
- 2019-01-14 CN CN201910033198.6A patent/CN109691997A/en active Pending
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5339811A (en) * | 1991-11-06 | 1994-08-23 | Mitsui Mining & Smelting Co., Ltd. | Magnetoencephalograph |
| US20040006267A1 (en) * | 2003-07-29 | 2004-01-08 | Buchanan D. Scott | Magnetically shielded room with internal active magnetic field cancellation, and its use |
| JP2005294537A (en) * | 2004-03-31 | 2005-10-20 | Takenaka Komuten Co Ltd | Panel-type coil, uniform magnetic field generator, gradient magnetic field generator and magnetic field canceling device |
| JP2008078529A (en) * | 2006-09-25 | 2008-04-03 | Mti:Kk | Magnetic shielding room of internal active magnetically shielded system |
| WO2010029725A1 (en) * | 2008-09-10 | 2010-03-18 | 株式会社竹中工務店 | Magnetic shield system and magnetic shield method |
| CN105022005A (en) * | 2014-04-23 | 2015-11-04 | 中国科学院上海微系统与信息技术研究所 | SQUID magnetic sensor measuring sensitivity enhancement method, device and system |
| CN106859629A (en) * | 2017-01-18 | 2017-06-20 | 上海理工大学 | Ambient noise weakens system and method in magneticencephalogram detection |
Non-Patent Citations (4)
| Title |
|---|
| 唐孝威: "《脑功能成像》", 31 October 1999, 合肥：中国科学技术大学出版社 * |
| 孙伟民等: "《光学原子磁力仪》", 31 August 2015 * |
| 张卫萍等: "《MRI技术与实验》", 30 June 2018, 镇江：江苏大学出版社 * |
| 韩丰谈等: "《医学影像设备学 第2版》", 31 July 2010 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN113183707A (en) * | 2021-05-21 | 2021-07-30 | 辽宁工业大学 | Design method and system of whole-vehicle active suspension self-adaptive fixed-period sampling controller |
| CN113183707B (en) * | 2021-05-21 | 2024-04-02 | 辽宁工业大学 | Design method and system of self-adaptive fixed-period sampling controller of full-vehicle active suspension |
| CN113967019A (en) * | 2021-05-28 | 2022-01-25 | 北京昆迈医疗科技有限公司 | Magnetoencephalography system and method of operating magnetoencephalography system |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108459282B (en) | Magnetoencephalogram detection device and method based on atomic magnetometer/magnetic gradiometer | |
| US4913152A (en) | Magnetoencephalograph (MEG) using a multi-axis magnetic gradiometer for localization and tracking of neuromagnetic signals | |
| CN104427931B (en) | Medical gaussmeter | |
| JP3204542B2 (en) | Magnetic field source measurement device | |
| US20090149736A1 (en) | Atomic magnetometer sensor array magnetic resonance imaging systems and methods | |
| US20050234329A1 (en) | Noise cancellation in magnetoencephalography and electroencephalography with isolated reference sensors | |
| WO1994028789A1 (en) | Apparatus and process for determining the sources of biomagnetic activity | |
| CN102988038B (en) | First-order gradient compensation module and method for unmask magnetocardiography | |
| Storm et al. | A modular, extendible and field-tolerant multichannel vector magnetometer based on current sensor SQUIDs | |
| CN111281370A (en) | Gradiometer configuration type magnetoencephalography system based on SERF atomic magnetometer | |
| Yang et al. | SQUID array with optimal compensating configuration for magnetocardiography measurement in different environments | |
| CN109691997A (en) | The detection method in brain detector for magnetic field and brain magnetic field | |
| CN112450935B (en) | Magnetocardiogram measuring method and system based on unshielded atom magnetometer | |
| CN116887752A (en) | Magnetoencephalography method and magnetoencephalography system | |
| Kong et al. | Multi-channel magnetocardiogardiography system based on low-Tc SQUIDs in an unshielded environment | |
| US11604236B2 (en) | Optimal methods to feedback control and estimate magnetic fields to enable a neural detection system to measure magnetic fields from the brain | |
| US20210247468A1 (en) | Systems and methods that exploit maxwell's equations and geometry to reduce noise for ultra-fine measurements of magnetic fields from the brain using a neural detection system | |
| Li et al. | SQUID-based MCG measurement using a full-tensor compensation technique in an urban hospital environment | |
| Maslennikov | Magnetocardiographic diagnostic complexes based on the MAG-SKAN SQUIDs | |
| CN112611994B (en) | Extremely-low-field nuclear magnetic resonance imaging system and baseline calibration method thereof | |
| CN113520399B (en) | Heart magnetic field simulation system based on Helmholtz coil array | |
| JPH0779948A (en) | Magnetic resonance imaging apparatus | |
| CN114264984B (en) | Method and system for measuring weak magnetic field of zero-field optical pump atomic magnetometer | |
| Klein et al. | A large and quick induction field scanner for examining the interior of extended objects or humans | |
| Yang et al. | Optimization of pick-up coils for weakly damped SQUID gradiometers |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20190430 |
|
| RJ01 | Rejection of invention patent application after publication |