CN109528879B - Chinese herbal medicine stabilizer and preparation method and application thereof - Google Patents
Chinese herbal medicine stabilizer and preparation method and application thereof Download PDFInfo
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Abstract
The invention discloses a Chinese herbal medicine stabilizer and a preparation method and application thereof, the stabilizer takes Bishore flower, radix cynanchi wilfordii and radix Anisodi Acutanguli as main materials, red date and almond as auxiliary materials, the main materials are respectively crushed, crude extract is extracted, the crude extract is mixed and filtered to obtain a composite solution, and the composite solution is subjected to ultrasonic extraction, concentration and freeze drying to obtain the stabilizer. The product can be used for the waterless keep-alive transportation of fresh and live aquatic products, so that the aquatic products are calmed and dormant, the metabolism rate is reduced, the casualties are reduced, the survival rate is improved, and particularly, the effect of stabilizing fishes is more remarkable. The Chinese herbal medicine tranquilizer has the advantages of low toxic and side effects, safety, reliability, low cost and excellent sedation effect.
Description
Technical Field
The invention relates to the field of aquatic product anesthetics, in particular to a Chinese herbal medicine stabilizer and a preparation method and application thereof.
Background
With the improvement of living standard, people increasingly demand aquatic products, and especially fresh and live aquatic products are more favored by consumers. At present, in order to ensure that aquatic products are in a quiet and stable environment in the transportation process, people usually use chemical pharmaceutical agents to stabilize the aquatic products, so that the aquatic products are calmed and enter a dormant state, the metabolic strength is reduced, the oxygen consumption is reduced, the stress reaction and the damage caused by mutual collision in the transportation process are reduced, and the purpose of improving the survival rate of the aquatic products is further achieved.
The chemical medicines commonly used for stabilization of aquatic products at present comprise MS-222, eugenol, benzocaine hydrochloride and the like. However, they have many problems in the using process, for example, although MS-222 has the characteristics of fast recovery, high survival rate and fast entering of aquatic products into a stable state, FDA requires that edible fish anesthetized by MS-222 must go through a drug withdrawal period of 21 d to be put on the market for sale, and is expensive and limited in use; the eugenol has good stabilizing effect but short stabilizing time, and the residual quantity and residual time of the stabilizing agent in aquatic products are not clear whether the stabilizing agent has toxic effect on human bodies; the phenylzakh hydrochloride has sensitization on human and is easy to burn; aiming at the problems, a Chinese herbal medicine stabilizer which is nontoxic, harmless, safe, reliable, low in cost and excellent in calming effect is needed to be researched for the keep-alive transportation of aquatic products.
Disclosure of Invention
Aiming at the defects in the prior art, the invention aims to provide the Chinese herbal medicine stabilizer for solving the problems, which can be used for the waterless keep-alive transportation of fresh and live aquatic products, so that the aquatic products are calmed and dormant, the metabolism rate is reduced, the casualties are reduced, the survival rate is improved, and particularly, the stabilizing effect on fishes is more remarkable. The product takes the epidermis of Bishore flowers, radix cynanchi wilfordii and radix Anisodi Acutanguli as main materials and the red dates and almonds as auxiliary materials, and has the advantages of low toxic and side effects, safety, reliability, low cost and excellent calming effect.
In order to achieve the purpose, the invention provides the following technical scheme:
a Chinese herbal medicine stabilizer comprises the following components in parts by weight: 30-40 parts of Bishore flowers, 10-20 parts of spiny eggplant, 20-30 parts of the epidermis of the root of Anisodus acutangulus, 10-15 parts of red dates and 10-15 parts of almonds.
The Biyanhua belongs to Amaryllidaceae plants, is native to China Yangtze river basin, is distributed in the middle and lower reaches and southwest parts of Yangtze river, and has the effects of emetic, phlegm eliminating, swelling reducing, pain relieving, tranquilizing, anti-inflammatory and detoxifying.
Solanum torvum Linne is fruit of Solanaceae plant Solanum torvum Linne, and is distributed in Yunnan province. Collected in autumn and dried in the sun. Has effects in relieving inflammation, removing toxic materials, tranquilizing mind, and relieving pain. It can be used for treating rheumatic traumatic injury, nervous headache, gastralgia, toothache, mastitis, and parotitis.
The radix Anisodi Acutanguli belongs to Solanaceae plants, grows in forest margin, grassland and shady and humid places with elevation of 2700-. Can be used for treating fracture, traumatic injury, rheumatalgia, and gastrointestinal pain, and has effects of relieving pain, dispelling pathogenic wind, and removing dampness by oral administration or external application after soaking in wine.
Red dates, also known as Chinese dates, belong to the plant of angiosperma, dicotyledonae, Rhamnales, Rhamnaceae, Ziziphus. The vitamin content is very high, has the reputation of 'natural vitamin pill', and has the effects of nourishing yin, tonifying yang, enriching blood and improving immunity.
The almond is seed of Prunus armeniaca of Rosaceae, and is divided into sweet almond and bitter almond, which mainly contains protein, fat, sugar, and trace amygdalin. In China, many plants are cultivated in all parts of the country except for the heat zone of Guangdong, Hainan and the like. Mainly distributed in Hebei, Liaoning, northeast, North China and Gansu province. Contains abundant vitamin E, and has effects of protecting lymphocyte and erythrocyte.
The inventor obtains through experiments that the natural green stabilizer for the water-free keep-alive of aquatic products can be prepared by combining the extracts, and the effect is obvious. As the materials are all natural herbs, the use process has the characteristics of no pollution, high safety and the like.
The preparation method comprises the steps of respectively crushing Bishore flowers, radix solani spinosae, radix tripartite and radix tripartite epidermis, red dates and almonds in parts by weight, extracting a crude extract by a Soxhlet extraction method, mixing and filtering the crude extract to obtain a composite solution, and performing ultrasonic extraction, concentration and freeze drying on the composite solution to obtain the stabilizer.
The use method of the Chinese herbal medicine stabilizer comprises the following steps: 10-20 g of the stabilizer is taken, poured into 1000-2000L of clear water, stirred at 80-100 rpm for 3-6 min at room temperature to prepare a stabilizer solution, and different aquatic products are put into the stabilizer solution to be in a calm and dormant state.
The invention has the beneficial effects that:
1. provides a Chinese herbal medicine aquatic product waterless keep-alive induction stabilizer which can be used for keeping fishes, shrimps, crabs, shellfishes and the like alive before transportation and reducing the damage in the transportation process.
2. Compared with the traditional chemosynthesis tranquilizer, the Chinese herbal medicine tranquilizer has the advantages of low toxic and side effects, safety, reliability, practicability, high efficiency and high safety.
3. The stabilizer has the advantages of low preparation cost, easily obtained raw materials, simple operation, economy and environmental protection.
4. The stabilizer has moderate component proportion, and does not pollute aquatic products within a specified dosage range.
5. The tranquilizer contains fructus Jujubae and semen Armeniacae amarum crude extractive solution, and can protect lymphocyte in aquatic product and enhance immunity of aquatic product.
6. The stabilizer can be produced industrially.
Detailed Description
Components and preparation of the Chinese herbal medicine tranquilizer
Chinese herbal medicine stabilizer A:
30 parts of pilea, 20 parts of spiny eggplant, 25 parts of the epidermis of the root of the scopolia acutangula, 15 parts of red date and 10 parts of almond;
chinese herbal medicine stabilizer B:
40 parts of pilea, 10 parts of spiny nightshade, 20 parts of bark of three fennel roots, 10 parts of red dates and 10 parts of almonds;
chinese herbal medicine stabilizer C:
35 parts of petasites littoralis flower, 15 parts of spiny nightshade herb, 25 parts of bark of three fenugreek roots, 12 parts of red dates and 12 parts of almonds.
The preparation method comprises the following steps: respectively crushing Bishore flowers, radix cynanchi wilfordii, radix Anisodi Acutanguli, red dates and almonds of the above weight components, extracting a crude extract by a Soxhlet extraction method, mixing and filtering the crude extract to obtain a composite solution, and performing ultrasonic extraction, concentration and freeze drying on the composite solution to obtain the stabilizer. The method comprises the following specific steps:
1. preparation of crude extract of pilea flowers
(1) Bilao pretreatment
Putting the pilea flowers in parts by weight into a 20L plastic basin, cleaning with distilled water for 15min, taking out with a net tray, placing on a draining rack with the length and width of 1m and 0.5m respectively, draining for 1.5h at normal temperature, transferring into an electrothermal blowing drying box with the capacity of 0.8 x 1m, uniformly spreading on a shelf in an oven, and drying for 2h at 55 ℃. After drying, the flowers are transferred to trays with the length and width of 1m and 0.5m respectively, and stored in a refrigerator at 4 ℃ for 40min for later use.
(2) Extraction of crude extract of pilea flowers
Placing the riparian flower processed in the step (1) in a commercial pulverizer with the model of CS-2000, pulverizing at 200rpm for 3min, sieving the powder with a 140-mesh sieve, transferring to a storage tank with the capacity of 1000ml, and storing in dark place. Then, a crude extract was prepared by Soxhlet extraction, by taking out 120g of the powder with a spatula, placing into a filter paper cylinder having a height of 15cm and an inner diameter of 41mm, sealing the opening, and placing into an extraction cylinder having an inner diameter of 50 mm. Then, a 500mL flat-bottomed flask was set, two grains of zeolite were placed, and the height of the flask was adjusted so that it could just be immersed in water in a 701 st super constant temperature water bath tank. After the Soxhlet extraction device is installed, ethanol solution with the volume concentration of 95 percent and the amount of siphonage for two times is added into a reflux condenser pipe at the upper part of the device. Turning on the power supply of the water bath tank, heating and refluxing for 2.5 hr, siphoning for 13 times during extraction, stopping heating, repeating 2 groups, and mixing extractive solutions. Removing Soxhlet extractor, installing condenser tube for distillation, recovering ethanol to obtain pilea flower crude extract, and adding 30g anhydrous calcium chloride for dehydration. Dehydrating for 3h, filtering with 4 pieces of medical gauze at room temperature to obtain pilea solution, storing in 1000mL volumetric flask, and transferring to 4 deg.C refrigerator for 40 min.
2. Preparation of Roxburgh anoectochilus terminal bud crude extract
(1) Pretreatment of Solanum spinosum
Placing the burreria spinosa in a 20L plastic basin, cleaning with distilled water for 15min, fishing out with a net tray, draining water for 2h at normal temperature, transferring to the outdoor, laying a layer of film on the ground, uniformly spreading the burreria spinosa drained with water on the film, and naturally drying. Drying in the sun, cutting into 5 × 5 × 5mm blocks with a blade, placing on 0.5m and 0.5m trays, and storing in a 4 deg.C refrigerator for 40 min.
(2) Extraction of crude extract of radix Kadsurae Cochinchinensis
And (2) placing the solanum spinosum processed in the step (1) in a commercial pulverizer with the model number of CS-2000, pulverizing for 5min at 300rpm, sieving the powder with a 160-mesh sieve, transferring the powder into a storage tank with the capacity of 1000mL, and storing the powder in a dark place. Then, a crude extract was prepared by Soxhlet extraction, by taking out 100g of the powder with a spatula, placing it in a filter paper cylinder of 15cm in height and 41mm in inner diameter, sealing the opening, and placing it in an extraction cylinder of 50mm in inner diameter. Then, a 500mL flat-bottomed flask was set, two grains of zeolite were placed, and the height of the flask was adjusted so that it could just be immersed in water in a 701 st super constant temperature water bath tank. After the Soxhlet extraction device is installed, petroleum ether with enough siphonage for two times is added into a reflux condenser pipe at the upper part of the device. Turning on the power supply of the water bath tank, heating and refluxing for 3 hr, siphoning for 15 times during extraction, stopping heating when the color of the extractive solution in the extraction cylinder becomes light, repeating 2 groups, and mixing extractive solutions. Removing Soxhlet extractor, installing condenser tube for distillation, recovering petroleum ether to obtain crude extract of radix Kadsurae Cochinchinensis, and adding 30g anhydrous calcium chloride for dehydration. Dehydrating for 3 hr, filtering with 4 pieces of medical gauze at room temperature to obtain Kandelia candel solution, storing in 1000mL volumetric flask, and transferring to 4 deg.C refrigerator for 40 min.
3. Preparation of rough extract of epidermis of radix Anisodi Acutanguli
(1) Three-part pretreatment
The root of the radix Anisodi Acutanguli is taken and put into a 20L plastic basin, washed by distilled water for 15min, fished out by a net plate, drained for 2h at normal temperature, the epidermis is dried, the epidermis is peeled off by a blade, sliced, the thickness of the slice is 1cm, the slice is transferred to the outdoor and aired to 4, and then the slice is evenly spread on a shelf in an electrothermal blowing dry box with the capacity of 800X 1000mm and dried for 2h at the temperature of 55 ℃. After drying, the epidermis of the three thirds of the three parts is transferred to trays with the length and width of 0.5m and 0.5m respectively, and stored in a refrigerator at 4 ℃ for 40min for later use.
(2) Extraction of rough extract of epidermis of three-thirds root
And (2) putting the epidermis of the trisection root processed in the step (1) into a commercial pulverizer with the model of CS-2000, pulverizing at 300rpm for 3-5 mim, sieving the powder with a 160-mesh sieve, transferring to a storage tank with the capacity of 1000mL, and storing in a dark place. Then, a crude extract was prepared by Soxhlet extraction, by taking out 100g of the powder with a spatula, placing it in a filter paper cylinder of 15cm in height and 41mm in inner diameter, sealing the opening, and placing it in an extraction cylinder of 50mm in inner diameter. Then, a 500mL flat-bottomed flask was set, two grains of zeolite were placed, and the height of the flask was adjusted so that it could just be immersed in water in a 701 st super constant temperature water bath tank. After the Soxhlet extraction device is installed, petroleum ether with enough siphonage for two times is added into a reflux condenser pipe at the upper part of the device. And (3) turning on a power supply of a water bath tank, heating and refluxing for 3h, siphoning for 13-16 times in the extraction process, stopping heating when the color of the extracting solution in the extraction cylinder becomes light, repeating the step (2), and combining the extracting solutions. Removing the Soxhlet extractor, installing a condenser pipe for distillation, recovering petroleum ether to obtain the crude extract of radix Anisodi Acutanguli, and adding 30g of anhydrous calcium chloride for dehydration. Dehydrating for 3h, filtering with 4 pieces of medical gauze at room temperature to obtain Saacutangular solution, storing in 1000mL volumetric flask, and transferring to 4 deg.C refrigerator for 40 min.
4. Preparation of red date crude extract
(1) Red date pretreatment
Taking the red dates with the cores removed in parts by weight, placing the red dates in a 20L plastic basin, washing the red dates for 15min with distilled water, taking the red dates out with a net tray, draining the red dates for 2h at normal temperature, transferring the red dates into an electrothermal blowing drying oven with the capacity of 800X 1000mm, and drying the red dates for 2h at the temperature of 55 ℃. After drying, the red dates are transferred to trays with the length and width of 0.5m and 0.5m respectively, and stored in a refrigerator at 4 ℃ for 40min for later use.
(2) Red date crude extract extraction
And (3) placing the red dates processed in the step (1) in a commercial grinder with the model number of CS-2000, grinding for 3min at 400rpm, sieving the powder with a 140-mesh sieve, transferring the powder into a storage tank with the capacity of 1000mL, and storing the powder in a dark place. Then, a crude extract was prepared by Soxhlet extraction, by taking out 120g of the powder with a spatula, placing into a filter paper cylinder having a height of 15cm and an inner diameter of 41mm, sealing the opening, and placing into an extraction cylinder having an inner diameter of 50 mm. Then, a 500mL flat-bottomed flask was set, two grains of zeolite were placed, and the height of the flask was adjusted so that it could just be immersed in water in a 701 st super constant temperature water bath tank. A Soxhlet extraction device is installed, and ethanol solution with the volume concentration of 95 percent and the amount enough for twice siphoning is added into a reflux condenser pipe at the upper part of the device. Turning on the power supply of the water bath tank, heating and refluxing for 3 hr, siphoning for 12 times during extraction, stopping heating when the color of the extractive solution in the extraction cylinder becomes light, repeating 2 groups, and mixing extractive solutions. Removing Soxhlet extractor, installing condenser tube for distillation, recovering ethanol to obtain fructus Jujubae crude extract, and adding 30g anhydrous calcium chloride for dehydration. Dehydrating for 3h, filtering with 4 pieces of medical gauze at room temperature to obtain fructus Jujubae solution, storing in 1000mL volumetric flask, and transferring to 4 deg.C refrigerator for 40 min.
5. Preparation of coarse extract of almond
(1) Almond pretreatment
Taking the almonds in parts by weight, putting the almonds in a 20L plastic basin, washing the almonds with distilled water for 15min, fishing the almonds out by using a net tray, draining the water for 2h at normal temperature, transferring the almonds into an electrothermal blowing drying oven with the capacity of 800X 1000mm, and drying the almonds for 2h at the temperature of 55 ℃. After drying, the almonds are transferred to trays with the length and width of 0.8m and 0.5m respectively, and stored in a refrigeration house at 4 ℃ for 40min for later use.
(2) Extraction of crude extract of almond
And (3) putting the almonds processed in the step (1) into a commercial grinder with the model of CS-2000, grinding for 3min at 400rpm, sieving the powder with a 140-mesh sieve, transferring the powder into a storage tank with the capacity of 1000mL, and storing the powder in a dark place. Then, a crude extract was prepared by Soxhlet extraction, by taking out 120g of the powder with a spatula, placing into a filter paper cylinder having a height of 15cm and an inner diameter of 41mm, sealing the opening, and placing into an extraction cylinder having an inner diameter of 50 mm. Then, a 500mL flat-bottomed flask was set, two grains of zeolite were placed, and the height of the flask was adjusted so that it could just be immersed in water in a 701 st super constant temperature water bath tank. A Soxhlet extraction device is installed, and ethanol solution with the volume concentration of 95 percent and the amount of siphonage for two times is added into a reflux condenser pipe at the upper part of the device. Turning on the power supply of the water bath tank, heating and refluxing for 3 hr, siphoning for 12 times during extraction, stopping heating when the color of the extractive solution in the extraction cylinder becomes light, repeating 2 groups, and mixing extractive solutions. Removing Soxhlet extractor, installing condenser tube for distillation, recovering ethanol to obtain crude extract of semen Armeniacae amarum, and adding 30g anhydrous calcium chloride for dehydration. Dehydrating for 3h, filtering with 4 pieces of medical gauze at room temperature to obtain semen Armeniacae amarum solution, storing in 1000mL volumetric flask, and transferring to 4 deg.C refrigerator for 40 min.
6. Preparation of composite solution
Pouring the pilea flower crude extract prepared in the step 1, the burbergia robusta crude extract in the step 2, the radix Anisodi Acutanguli crude extract in the step 3, the red date crude extract prepared in the step 4 and the almond crude extract in the step 5 into a stirrer with the length, the width and the depth of 315 multiplied by 260 multiplied by 387mm and the model of HB-K800, stirring for 10min at the speed of 150rpm, standing for 2h at room temperature, superposing and filtering 4 pieces of medical gauze to prepare a composite solution, and putting the composite solution into a 1500mL volumetric flask for later use.
7. Preparation of ultrasonic extraction solution
And (3) transferring the composite solution prepared in the step (6) to an ultrasonic circulation extractor with the model of CF-1500C, turning on a power supply, performing ultrasonic extraction, setting the ultrasonic frequency of the ultrasonic extractor to be 35KHZ, setting the temperature to be 55 ℃, performing first extraction, stopping the extraction for 10min after 20min, performing second extraction for 2 times continuously, and keeping the extraction time the same. Then placing the extract into a centrifuge with MINI200 model, separating at 3000rpm to obtain ultrasonic extract, and placing into 2000mL volumetric flask for use.
8. Preparation of the concentrate
Pouring the ultrasonic extraction liquid prepared in the step 7 into a concentration tank, setting the vacuum degree at-0.065 Mpa and the water bath temperature at 70 ℃, stopping concentration until the specific gravity is 1:4, preparing a composite concentrated liquid, and putting the composite concentrated liquid into a 2000ml volumetric flask for later use.
9. Preparation of the stabilizers
And (3) filling the composite concentrated solution prepared in the step (8) into a 2000mL freezing bottle, putting the freezing bottle into a refrigerator with the temperature of 18 ℃ below zero for freezing for 12 hours, connecting the freezing bottle to a freezing dryer with the model of LC-12N-50A, setting the temperature of a cold trap to be 45 ℃ below zero and the pressure of a drying chamber to be 65Pa, and drying for 12 hours to prepare composite powder, namely the Chinese herbal medicine stabilizer special for aquatic product transportation.
Secondly, testing effect determination:
the mechanism of action of the stabilizer is as follows: the fish can lose touch sense by inhibiting cerebral cortex, act on basal ganglia and cerebellum to excite, act on spinal cord, and enter anesthesia state.
Test example 1: taking loach adult fish as an example, taking 0.8g of stabilizer A, stabilizer B and stabilizer C, respectively pouring into 100L clear water bucket, stirring at room temperature at 100rpm for 5min to obtain stabilizer solution A, stabilizer solution B and stabilizer solution C. The experimental observation results of transferring the adult loaches into the stabilizer solution are as follows:
table (1.1) shows the calming effect of adult loaches:
| index (I) | Mean time to unbalance | Mean settling time | Mean time to resuscitation | Survival rate after 48h of resuscitation | Detection of in vivo tranquilizer component after 48h of resuscitation |
| Stabilizer solution group A | 2min23s | 2min57s | 7min43s | 100% | Is free of |
| Stabilizer solution group B | 2min20s | 2min46s | 7min42s | 100% | Is free of |
| Stabilizer solution group C | 2min21s | 3min02s | 7min40s | 100% | Is free of |
Collecting stabilizer A, stabilizer B and stabilizer C1.2 g, respectively pouring into 150L clear water tank, stirring at 100rpm at room temperature for 5min to obtain stabilizer transport solution A, stabilizer transport solution B and stabilizer transport solution C. And then transferring the adult loaches into a bucket, and carrying out keep-alive transportation on the adult loaches after the adult loaches enter a slight stability state.
Table (1.2) shows the stabilizing effect of the loach adult fish during transportation:
| index (I) | Slight settling time | Length of slightly settled transport | Average length of resuscitation | Transporting slightly stably for 48h, and survival rate after resuscitation | Detection of in vivo tranquilizer component after 48h of resuscitation |
| Group A for transporting and infusing stabilizer | 1min30s | 48h | 1h36min | 100% | Is free of |
| Group B for transporting and infusing stabilizer | 1min25s | 48h | 1h25min | 100% | Is free of |
| Stabilizer transport fluids group C | 1min31s | 48h | 1h36min | 100% | Is free of |
Test example 2: taking adult grouper as an example, collecting stabilizer A, stabilizer B and stabilizer C1 g, respectively pouring into 100L seawater barrel, stirring at room temperature at 100rpm for 5min to obtain stabilizer solution A, stabilizer solution B and stabilizer solution C. Adjusting the water temperature to 19 ℃, connecting aeration stone to introduce air into the water, then putting the grown grouper into a barrel, and putting the grown grouper into a calm and dormant state.
Table (2.1) shows the stabilizing effect of adult grouper:
| index (I) | Mean time to unbalance | Mean settling time | Mean time to resuscitation | Survival rate after 48h of resuscitation | Detection of in vivo tranquilizer component after 48h of resuscitation |
| Stabilizer solution group A | 2min14s | 2min48s | 7min58s | 100% | Is free of |
| Stabilizer solution group B | 2min12s | 2min31s | 7min55s | 100% | Is free of |
| Stabilizer solution group C | 2min11s | 2min36s | 7min54s | 100% | Is free of |
Collecting stabilizer A, stabilizer B and stabilizer C1.4 g, respectively pouring into 150L seawater barrel, stirring at 100rpm at room temperature for 5min to obtain stabilizer transport solution A, stabilizer transport solution B and stabilizer transport solution C. And then transferring the adult grouper into a barrel, and carrying out keep-alive transportation on the adult grouper after the adult grouper enters slight stability.
Table (2.2) shows the stabilizing effect of adult grouper during transportation:
| index (I) | Slight settling time | Length of slightly settled transport | Average length of resuscitation | Slightly stably transporting for 30h, and survival rate after resuscitation | Detection of in vivo tranquilizer component after 48h of resuscitation |
| Group A for transporting and infusing stabilizer | 1min45s | 30h | 54min17s | 100% | Is free of |
| Group B for transporting and infusing stabilizer | 1min39s | 30h | 56min21s | 100% | Is free of |
| Stabilizer transport fluids group C | 1min42s | 30h | 56min18s | 100% | Is free of |
The Chinese herbal medicine tranquilizer can realize industrialized production, and a production realization system comprises the following embodiments:
cleaning, drying, crushing, preparing a crude extract, an ultrasonic extract, a concentrated solution and freeze drying are carried out on Bishanhua, Kandelia spinulosa, Satsumadai, red date and almond in an industrial production system consisting of a cleaning workshop, a drying workshop, a crushing workshop, a liquid preparation workshop, an extraction workshop, a concentration workshop and a drying workshop to obtain the powder.
The cleaning workshop mainly comprises a raw material box, a U-shaped conveyor belt, a water pipe, a water tank, a cleaning machine and a water adding and draining device (used for adding water to the cleaning machine and draining water from the water tank); the raw materials are directly transported to an inlet of the cleaning pool from the warehouse and are respectively loaded into the raw material boxes, then the raw material boxes are placed on a U-shaped conveyor belt and conveyed to the end of the cleaning machine, the materials are poured into the cleaning machine pool, water in the cleaning machine is provided by a water adding device, wastewater flows into the pool through a water pipe and enters a purifying device through the pool, and the purified water flows into the cleaning machine through the water pipe. After the cleaning is finished, the materials are placed into a horizontal conveying belt and conveyed into a drying workshop.
The drying workshop mainly comprises a drying box and a conveyor belt; transferring the cleaned and drained materials from the cleaning workshop to a drying workshop, putting the materials into each tray, transferring the riparian flower, the red dates and the almonds into a drying box for drying, taking out the materials after drying, pouring the materials into a conveyor belt, and transferring the materials into a crushing workshop; transferring the solanum torvum into a transfer box, transferring the solanum torvum into the outdoor through a conveyor belt, drying the solanum torvum to 3-4 days, transferring the solanum torvum into a drying box through the conveyor belt, and transferring the solanum torvum into a crushing workshop; and transferring the trisection into a transfer box, transferring the trisection into the outdoor through a conveyor belt, naturally drying the trisection, transferring the trisection into a storage box through the conveyor belt, and transferring the trisection into a crushing workshop.
The crushing workshop mainly comprises a crusher, a screening and screening machine, a conveyor belt and a slideway; the materials to be dried are conveyed to a crushing workshop and directly poured into a crusher for stirring and crushing, the crushed materials are conveyed into a screening machine through a pipeline for screening, the materials with larger diameters and incapable of passing through the screening machine are conveyed into the crusher through a slideway for continuous stirring and crushing, and the powder passing through the screening machine is poured into a conveyor belt to be conveyed to a liquid-making workshop.
The liquid-making workshop mainly comprises a stirrer, a filtering device, a solvent storage tank, a recovery pipe and a pipeline. During the powder after smashing directly spreads into the mixer, proper amount clear water or organic solvent are poured into to the mixer to the rethread solvent bin, stir again, wait to stir the back that finishes, open mixer solution and flow into filter equipment through the pipeline, flow into the mixer through the back flow with the filter residue, stir once more. The filtered solution flows into an ultrasonic extractor through a pipeline, the extracted extracting solution flows into a centrifugal machine through a pipeline, then separation and extraction are carried out, and the separated extracting solution flows into a concentration workshop through a pipeline.
The concentration workshop mainly comprises a spherical vacuum concentration tank and a pipeline; and (3) allowing the separated extracting solution to flow into a spherical vacuum concentration tank through a pipeline for concentration, and allowing the concentrated solution to flow into a drying workshop through a pipeline after the concentration is finished.
The drying workshop mainly comprises a vacuum freeze dryer and a full-automatic powder filling, corking and capping machine; the concentrated solution flows into a drying workshop through a pipeline, is subpackaged and is put into or connected with a vacuum freeze dryer; collecting the freeze-dried powder, and packaging by a full-automatic powder filling, corking and capping machine to form the product.
Claims (2)
1. The Chinese herbal medicine stabilizer is characterized by comprising the following components in parts by weight: 30-40 parts of Bishore flowers, 10-20 parts of spiny eggplant, 20-30 parts of the epidermis of the root of Anisodus acutangulus, 10-15 parts of red dates and 10-15 parts of almonds.
2. The use of a herbal stabilizer of claim 1 in the transportation of aquatic products.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102284000A (en) * | 2011-05-26 | 2011-12-21 | 张忠宏 | Medicated liquor |
| CN106138422A (en) * | 2015-04-15 | 2016-11-23 | 王言 | A kind of medicated wine and preparation method thereof |
| CN107693690A (en) * | 2017-11-14 | 2018-02-16 | 何芬 | A kind of medicinal liquor |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102284000A (en) * | 2011-05-26 | 2011-12-21 | 张忠宏 | Medicated liquor |
| CN106138422A (en) * | 2015-04-15 | 2016-11-23 | 王言 | A kind of medicated wine and preparation method thereof |
| CN107693690A (en) * | 2017-11-14 | 2018-02-16 | 何芬 | A kind of medicinal liquor |
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Application publication date: 20190329 Assignee: Hebei zewen Biotechnology Co.,Ltd. Assignor: HUAIYIN INSTITUTE OF TECHNOLOGY Contract record no.: X2021980014969 Denomination of invention: Chinese herbal medicine stabilizer and its preparation method and Application Granted publication date: 20210817 License type: Common License Record date: 20211222 |
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