CN109527538A - It is a kind of to treat sorbefacient nutritional agents of osteoporosis and preparation method thereof - Google Patents
It is a kind of to treat sorbefacient nutritional agents of osteoporosis and preparation method thereof Download PDFInfo
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- CN109527538A CN109527538A CN201811316517.6A CN201811316517A CN109527538A CN 109527538 A CN109527538 A CN 109527538A CN 201811316517 A CN201811316517 A CN 201811316517A CN 109527538 A CN109527538 A CN 109527538A
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- 235000016709 nutrition Nutrition 0.000 title claims abstract description 54
- 208000001132 Osteoporosis Diseases 0.000 title claims abstract description 36
- 238000002360 preparation method Methods 0.000 title claims abstract description 10
- 239000003795 chemical substances by application Substances 0.000 claims abstract description 33
- 235000002017 Zea mays subsp mays Nutrition 0.000 claims abstract description 28
- 150000001875 compounds Chemical class 0.000 claims abstract description 22
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 claims abstract description 21
- 235000005822 corn Nutrition 0.000 claims abstract description 21
- CJWQYWQDLBZGPD-UHFFFAOYSA-N isoflavone Natural products C1=C(OC)C(OC)=CC(OC)=C1C1=COC2=C(C=CC(C)(C)O3)C3=C(OC)C=C2C1=O CJWQYWQDLBZGPD-UHFFFAOYSA-N 0.000 claims abstract description 14
- 150000002515 isoflavone derivatives Chemical class 0.000 claims abstract description 14
- 235000008696 isoflavones Nutrition 0.000 claims abstract description 14
- 241000186000 Bifidobacterium Species 0.000 claims abstract description 13
- 239000006041 probiotic Substances 0.000 claims abstract description 13
- 235000018291 probiotics Nutrition 0.000 claims abstract description 13
- 239000002994 raw material Substances 0.000 claims abstract description 7
- 238000000855 fermentation Methods 0.000 claims description 34
- 230000004151 fermentation Effects 0.000 claims description 34
- 240000008042 Zea mays Species 0.000 claims description 26
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 25
- 241000894006 Bacteria Species 0.000 claims description 22
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims description 18
- 229910000831 Steel Inorganic materials 0.000 claims description 14
- 239000010959 steel Substances 0.000 claims description 14
- 238000004659 sterilization and disinfection Methods 0.000 claims description 14
- 238000003756 stirring Methods 0.000 claims description 14
- 235000015099 wheat brans Nutrition 0.000 claims description 11
- 241000186046 Actinomyces Species 0.000 claims description 9
- 241000235342 Saccharomycetes Species 0.000 claims description 9
- 235000014655 lactic acid Nutrition 0.000 claims description 9
- 239000004310 lactic acid Substances 0.000 claims description 9
- 238000000034 method Methods 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 241000196324 Embryophyta Species 0.000 claims description 8
- 238000009395 breeding Methods 0.000 claims description 8
- 230000001488 breeding effect Effects 0.000 claims description 8
- 229920000742 Cotton Polymers 0.000 claims description 7
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 claims description 7
- 238000001035 drying Methods 0.000 claims description 7
- 235000009973 maize Nutrition 0.000 claims description 7
- 238000002156 mixing Methods 0.000 claims description 7
- 229910001220 stainless steel Inorganic materials 0.000 claims description 7
- 239000010935 stainless steel Substances 0.000 claims description 7
- 230000001954 sterilising effect Effects 0.000 claims description 7
- 241000191967 Staphylococcus aureus Species 0.000 claims description 6
- 238000009423 ventilation Methods 0.000 claims description 6
- 235000013312 flour Nutrition 0.000 claims description 3
- 239000000843 powder Substances 0.000 claims description 2
- 230000000050 nutritive effect Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 7
- 206010006187 Breast cancer Diseases 0.000 abstract description 2
- 208000026310 Breast neoplasm Diseases 0.000 abstract description 2
- 206010008342 Cervix carcinoma Diseases 0.000 abstract description 2
- 208000006105 Uterine Cervical Neoplasms Diseases 0.000 abstract description 2
- 201000010881 cervical cancer Diseases 0.000 abstract description 2
- 102000015694 estrogen receptors Human genes 0.000 abstract description 2
- 108010038795 estrogen receptors Proteins 0.000 abstract description 2
- 201000001275 rectum cancer Diseases 0.000 abstract description 2
- 241000209149 Zea Species 0.000 abstract 2
- 230000037182 bone density Effects 0.000 description 13
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 7
- 239000011575 calcium Substances 0.000 description 7
- 229910052791 calcium Inorganic materials 0.000 description 7
- 230000008859 change Effects 0.000 description 5
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 229930003944 flavone Natural products 0.000 description 3
- 235000011949 flavones Nutrition 0.000 description 3
- 238000001727 in vivo Methods 0.000 description 3
- 230000035764 nutrition Effects 0.000 description 3
- 239000000126 substance Substances 0.000 description 3
- OILXMJHPFNGGTO-UHFFFAOYSA-N (22E)-(24xi)-24-methylcholesta-5,22-dien-3beta-ol Natural products C1C=C2CC(O)CCC2(C)C2C1C1CCC(C(C)C=CC(C)C(C)C)C1(C)CC2 OILXMJHPFNGGTO-UHFFFAOYSA-N 0.000 description 2
- RQOCXCFLRBRBCS-UHFFFAOYSA-N (22E)-cholesta-5,7,22-trien-3beta-ol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CCC(C)C)CCC33)C)C3=CC=C21 RQOCXCFLRBRBCS-UHFFFAOYSA-N 0.000 description 2
- OQMZNAMGEHIHNN-UHFFFAOYSA-N 7-Dehydrostigmasterol Natural products C1C(O)CCC2(C)C(CCC3(C(C(C)C=CC(CC)C(C)C)CCC33)C)C3=CC=C21 OQMZNAMGEHIHNN-UHFFFAOYSA-N 0.000 description 2
- 241000186016 Bifidobacterium bifidum Species 0.000 description 2
- DNVPQKQSNYMLRS-NXVQYWJNSA-N Ergosterol Natural products CC(C)[C@@H](C)C=C[C@H](C)[C@H]1CC[C@H]2C3=CC=C4C[C@@H](O)CC[C@]4(C)[C@@H]3CC[C@]12C DNVPQKQSNYMLRS-NXVQYWJNSA-N 0.000 description 2
- 229940002008 bifidobacterium bifidum Drugs 0.000 description 2
- 239000008280 blood Substances 0.000 description 2
- 210000004369 blood Anatomy 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- DNVPQKQSNYMLRS-SOWFXMKYSA-N ergosterol Chemical compound C1[C@@H](O)CC[C@]2(C)[C@H](CC[C@]3([C@H]([C@H](C)/C=C/[C@@H](C)C(C)C)CC[C@H]33)C)C3=CC=C21 DNVPQKQSNYMLRS-SOWFXMKYSA-N 0.000 description 2
- 150000002213 flavones Chemical class 0.000 description 2
- 239000005556 hormone Substances 0.000 description 2
- 229940088597 hormone Drugs 0.000 description 2
- 230000006872 improvement Effects 0.000 description 2
- 241000193830 Bacillus <bacterium> Species 0.000 description 1
- 206010006956 Calcium deficiency Diseases 0.000 description 1
- 201000009030 Carcinoma Diseases 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 244000068988 Glycine max Species 0.000 description 1
- 235000010469 Glycine max Nutrition 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- DCTLJGWMHPGCOS-UHFFFAOYSA-N Osajin Chemical compound C1=2C=CC(C)(C)OC=2C(CC=C(C)C)=C(O)C(C2=O)=C1OC=C2C1=CC=C(O)C=C1 DCTLJGWMHPGCOS-UHFFFAOYSA-N 0.000 description 1
- OUZCFMSJGDEXRT-UHFFFAOYSA-N Scandinone Natural products O=C1C=2C(OC)=C(CC=C(C)C)C=3OC(C)(C)C=CC=3C=2OC=C1C1=CC=C(O)C=C1 OUZCFMSJGDEXRT-UHFFFAOYSA-N 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- XSTXAVWGXDQKEL-UHFFFAOYSA-N Trichloroethylene Chemical compound ClC=C(Cl)Cl XSTXAVWGXDQKEL-UHFFFAOYSA-N 0.000 description 1
- 238000010521 absorption reaction Methods 0.000 description 1
- 230000005784 autoimmunity Effects 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000036772 blood pressure Effects 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 229960005309 estradiol Drugs 0.000 description 1
- 229930182833 estradiol Natural products 0.000 description 1
- 229940011871 estrogen Drugs 0.000 description 1
- 239000000262 estrogen Substances 0.000 description 1
- -1 flavone compound Chemical class 0.000 description 1
- 238000001794 hormone therapy Methods 0.000 description 1
- 229910052500 inorganic mineral Inorganic materials 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 239000011707 mineral Substances 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 235000008935 nutritious Nutrition 0.000 description 1
- 239000003075 phytoestrogen Substances 0.000 description 1
- 239000002243 precursor Substances 0.000 description 1
- 102000005962 receptors Human genes 0.000 description 1
- 108020003175 receptors Proteins 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 210000000689 upper leg Anatomy 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 150000003722 vitamin derivatives Chemical class 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/135—Bacteria or derivatives thereof, e.g. probiotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/10—Washing or bathing preparations
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Mycology (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Animal Behavior & Ethology (AREA)
- Botany (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Microbiology (AREA)
- Medicinal Chemistry (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Dermatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
Sorbefacient nutritional agents of osteoporosis and preparation method thereof is treated the invention discloses a kind of, is made of the raw material for including following parts by weight: corn isoflavones 25~30%；Probiotics 1~2%；Multivitamin 1~2%；Compound nutritional pulvis 50~80%, the present invention are treated using probiotics corn isoflavones, because itself has the compatibility of selective estrogen receptor, can be reduced and be suffered from breast cancer, Cervical cancer, carcinoma of the rectum risk, play the role of eliminating canceration；Simultaneously because the effect of Bifidobacterium, increases being absorbed and utilized for isoflavones.
Description
Technical field
The present invention relates to medical nutritious technical field more particularly to it is a kind of treat the sorbefacient nutritional agents of osteoporosis and
Preparation method.
Background technique
Osteoporosis conventional approach is calcium deficiency, and osteoporosis needs are replenished the calcium, this is a mistaken ideas, is replenished the calcium too busy to get away
VD3, but vD3 is hardly produced in human body, here it is the incurable main causes of domestic and international osteoporosis.Expert says shine too more
Sun seeks to allow generates vD3 in vivo, but ultraviolet light excessively irradiates and is easy to suffer from cutaneum carcinoma, and ultraviolet light need to be converted into it is red
Outside line generates vD3 in vivo, and conversion time is long, and effect is unobvious.
Osteoporosis is mainly in 45 years old or more women and the elderly.The disease can cause overall pain, bow-backed, fracture etc.,
Especially 70 years old or more elderly patients are almost exactly to be unable to out-of-bed activity for a long time once fracturing.It is clinical to mostly use hormone replacement greatly
Therapy has certain effect, but cancered risk is high；Conservative treatment osteoporosis is with conventional calcium, magnesium and bone mostly
Change triol, bone density is begun to ramp up will be at 3 years or so, and treatment time is long, and is not easy to absorb.
Isoflavones is flavone compound, is a kind of bioactive substance, due to being to be extracted from plants, osajin master
There are in leguminous plant, the wherein content highest in soybean, therefore especially referred to as isoflavones.Isoflavones chemical structure
It is similar to the chemical structure of 17 β, mono- estradiol, it can play similar estrogen in conjunction with estrogen receptor and regulation endogenous is female
Functions of hormones, so the phytoestrogen that is otherwise known as.
Summary of the invention
Of the invention provide a kind of treats sorbefacient nutritional agents of osteoporosis and preparation method thereof.
The scheme of the invention is:
It is a kind of to treat the sorbefacient nutritional agents of osteoporosis, it is made of the raw material for including following parts by weight:
As a preferred technical solution, by including that the raw material of following parts by weight is made:
The probiotics are Bifidobacterium as a preferred technical solution,.
The compound nutritional pulvis is by including corn flour, brown sugar, wheat bran, water and leavening as a preferred technical solution,.
The leavening includes that Bifidobacterium, actinomyces, saccharomycete, lactic acid bacteria are therein as a preferred technical solution,
One or more mixtures.
The present invention also provides a kind of methods for preparing the treatment sorbefacient nutritional agents of osteoporosis, including the following steps:
1) crush maize is mixed to 300 mesh with wheat bran；
2) brown sugar with 100 degree boiled water disinfection and sterilization 30 minutes, it is cold to be really put into rustless steel container to 50 DEG C；
3) warm water stirring is added in leavening, and breeding expands two hours, is subsequently added in step 2) rustless steel container, three is small
When expanding propagation, be then mixed with step 1) corn bran, suitable water be during which added, be put into the stirring of stainless steel blender
10 minutes, stacking covered ten layers of white cotton fermentation at mountain type；
3) fermentation time 10 days are turned over once daily, until last day opens and completes zymotechnique；
4) drying process obtains compound nutritional pulvis after fermentation within ten days；
5) the compound nutritional pulvis of 50~80% parts by weight and the probiotics of 1~2% parts by weight, 25~30% weight are taken
The treatment sorbefacient nutrition of osteoporosis is made in the corn isoflavones of part, the multivitamin mixing of 1~2 parts by weight
Agent.
As a preferred technical solution, in the step 3) when fermentation, fermentation plant keeps ventilation device, the Indoor Temperature
Degree is not less than 20 DEG C, and humidity is 70~80%.
Sramana's formula bacterium, will must not be detected by being made in compound nutritional pulvis in the step 4) as a preferred technical solution,
He formula bacterium, staphylococcus aureus.
The leavening is Bifidobacterium, actinomyces, saccharomycete, lactic acid bacteria therein one as a preferred technical solution,
Kind or a variety of mixtures.
By adopting the above-described technical solution, a kind of treat sorbefacient nutritional agents of osteoporosis and preparation method thereof,
Include the following steps: that 1) crush maize is mixed to 300 mesh with wheat bran；2) brown sugar with 100 degree boiled water disinfection and sterilization 30 minutes, it is cold
Really rustless steel container is put into 50 DEG C；3) warm water stirring is added in leavening, and breeding expands two hours, is subsequently added to step 2) not
It becomes rusty in steel container, three hours expanding propagations are then mixed with step 1) corn bran, and suitable water is during which added, is put into
Stainless steel blender stirs 10 minutes, and stacking covers ten layers of white cotton fermentation at mountain type；3) fermentation time 10 days, are turned over daily
Once, until last day opens and completes zymotechnique；4) drying process obtains composite nutrition powder after fermentation within ten days
Agent；5) the compound nutritional pulvis of 50~80% parts by weight and the probiotics of 1~2% parts by weight, 25~30% parts by weight are taken
The treatment sorbefacient nutritional agents of osteoporosis is made in the multivitamin mixing of corn isoflavones, 1~2 parts by weight.
Advantages of the present invention: the present invention is treated using probiotics corn isoflavones, because itself having selectivity is female to swash
The compatibility of plain receptor can be reduced and be suffered from breast cancer, Cervical cancer, carcinoma of the rectum risk, play the role of eliminating canceration；Simultaneously because bifid
The effect of bacillus increases being absorbed and utilized for isoflavones；And the technology of the present invention utilizes corn, wheat bran, water, brown sugar addition unwrapping wire
Bacterium, the probiotics such as Bifidobacterium Bifidum contain vD3 precursor ergosterol, isoflavones, nucleic acid, vitamin, enzyme after fermentation
Deng, the function of the helpful absorption of Bifidobacterium Bifidum, ergosterol generates vD3 after entering in vivo, increase bone density T value fast, half a year
Left and right can rise 50% or more, significantly reduce mono- L4 lumbar vertebrae of L2, the bone density loss of neck of femur and rotor, and ensure blood calcium
Normally；Without cancer stricken risk, than clinically with hormone therapy safety；Secondly the present invention is also bright to treatment chronic enterogastritis effect
It is aobvious, and can effectively prevent disease of old people, improve autoimmunity, and effectively steady blood pressure.
Specific embodiment
In order to make up the above deficiency, the sorbefacient nutritional agents of osteoporosis and its preparation are treated the present invention provides a kind of
Method, to solve the problems in above-mentioned background technique.
It is a kind of to treat the sorbefacient nutritional agents of osteoporosis, it is made of the raw material for including following parts by weight:
It is made of the raw material for including following parts by weight:
The probiotics are Bifidobacterium.
The compound nutritional pulvis is by including corn flour, brown sugar, wheat bran, water and leavening.
The leavening includes that Bifidobacterium, actinomyces, saccharomycete, lactic acid bacteria be one such or a variety of mixtures.
The present invention also provides a kind of methods for preparing the treatment sorbefacient nutritional agents of osteoporosis, including the following steps:
1) crush maize is mixed to 300 mesh with wheat bran；
2) brown sugar with 100 degree boiled water disinfection and sterilization 30 minutes, it is cold to be really put into rustless steel container to 50 DEG C；
3) warm water stirring is added in leavening, and breeding expands two hours, is subsequently added in step 2) rustless steel container, three is small
When expanding propagation, be then mixed with step 1) corn bran, suitable water be during which added, be put into the stirring of stainless steel blender
10 minutes, stacking covered ten layers of white cotton fermentation at mountain type；
3) fermentation time 10 days are turned over once daily, until last day opens and completes zymotechnique；
4) drying process obtains compound nutritional pulvis after fermentation within ten days；
5) the compound nutritional pulvis of 50~80% parts by weight and the probiotics of 1~2% parts by weight, 25~30% weight are taken
The treatment sorbefacient nutrition of osteoporosis is made in the corn isoflavones of part, the multivitamin mixing of 1~2 parts by weight
Agent.
In the step 3) when fermentation, fermentation plant keeps ventilation device, and the room temperature is not less than 20 DEG C, and humidity is
70~80%.
It is made in the step 4) in compound nutritional pulvis and must not detect sramana's formula bacterium, will congratulates formula bacterium, Staphylococcus aureus
Bacterium.
The leavening is that Bifidobacterium, actinomyces, saccharomycete, lactic acid bacteria be one such or a variety of mixtures.
In order to be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, tie below
Specific embodiment is closed, the present invention is further explained.
Embodiment one: 1) crush maize is mixed to 300 mesh with wheat bran；
2) brown sugar with 100 degree boiled water disinfection and sterilization 30 minutes, it is cold to be really put into rustless steel container to 50 DEG C；
3) warm water stirring is added in leavening, and breeding expands two hours, is subsequently added in step 2) rustless steel container, three is small
When expanding propagation, be then mixed with step 1) corn bran, suitable water be during which added, be put into the stirring of stainless steel blender
10 minutes, stacking covered ten layers of white cotton fermentation at mountain type；
3) fermentation time 10 days are turned over once daily, until last day opens and completes zymotechnique；
4) drying process obtains compound nutritional pulvis after fermentation within ten days；
5) take probiotics, the corn of 30% parts by weight of the compound nutritional pulvis of 80% parts by weight and 2% parts by weight different
The treatment sorbefacient nutritional agents of osteoporosis is made in the multivitamin mixing of flavones, 2 parts by weight.
In the step 3) when fermentation, fermentation plant keeps ventilation device, and the room temperature is not less than 20 DEG C, and humidity is
70~80%.
It is made in the step 4) in compound nutritional pulvis and must not detect sramana's formula bacterium, will congratulates formula bacterium, Staphylococcus aureus
Bacterium.
The leavening is that Bifidobacterium, actinomyces, saccharomycete, lactic acid bacteria be one such or a variety of mixtures.
Embodiment two: 1) crush maize is mixed to 300 mesh with wheat bran；
2) brown sugar with 100 degree boiled water disinfection and sterilization 30 minutes, it is cold to be really put into rustless steel container to 50 DEG C；
3) warm water stirring is added in leavening, and breeding expands two hours, is subsequently added in step 2) rustless steel container, three is small
When expanding propagation, be then mixed with step 1) corn bran, suitable water be during which added, be put into the stirring of stainless steel blender
10 minutes, stacking covered ten layers of white cotton fermentation at mountain type；
3) fermentation time 10 days are turned over once daily, until last day opens and completes zymotechnique；
4) drying process obtains compound nutritional pulvis after fermentation within ten days；
5) take probiotics, the corn of 25% parts by weight of the compound nutritional pulvis of 50% parts by weight and 1% parts by weight different
The treatment sorbefacient nutritional agents of osteoporosis is made in the multivitamin mixing of flavones, 1 parts by weight.
In the step 3) when fermentation, fermentation plant keeps ventilation device, and the room temperature is not less than 20 DEG C, and humidity is
70~80%.
It is made in the step 4) in compound nutritional pulvis and must not detect sramana's formula bacterium, will congratulates formula bacterium, Staphylococcus aureus
Bacterium.
The leavening is that Bifidobacterium, actinomyces, saccharomycete, lactic acid bacteria be one such or a variety of mixtures.
Embodiment three:
1) crush maize is mixed to 300 mesh with wheat bran；
2) brown sugar with 100 degree boiled water disinfection and sterilization 30 minutes, it is cold to be really put into rustless steel container to 50 DEG C；
3) warm water stirring is added in leavening, and breeding expands two hours, is subsequently added in step 2) rustless steel container, three is small
When expanding propagation, be then mixed with step 1) corn bran, suitable water be during which added, be put into the stirring of stainless steel blender
10 minutes, stacking covered ten layers of white cotton fermentation at mountain type；
3) fermentation time 10 days are turned over once daily, until last day opens and completes zymotechnique；
4) drying process obtains compound nutritional pulvis after fermentation within ten days；
5) corn of the compound nutritional pulvis of 75% parts by weight and the probiotics of 1.5% parts by weight, 26% parts by weight is taken
The treatment sorbefacient nutritional agents of osteoporosis is made in the multivitamin mixing of isoflavones, 1% parts by weight.
In the step 3) when fermentation, fermentation plant keeps ventilation device, and the room temperature is not less than 20 DEG C, and humidity is
70~80%.
It is made in the step 4) in compound nutritional pulvis and must not detect sramana's formula bacterium, will congratulates formula bacterium, Staphylococcus aureus
Bacterium.
The leavening is that Bifidobacterium, actinomyces, saccharomycete, lactic acid bacteria be one such or a variety of mixtures.
Manufactured nutritional agents and medical calcium tablet compare test to severe sufferers of osteoporosis face in Example three, altogether
20 people, every group ten people, every group five male five female, the age of two groups of crowd is mutually all 70 years old, no other diseases, administration time
Bone density inspection, which is carried out, for half a year, after half a year takes the serious osteoporosis bone mineral density of one group of medical calcium tablet without change
Change, take after half a year one group of nutritional agents described in embodiment three of serious osteoporosis change object for appreciation bone density T value rise 1 to
Between one 1.5, blood calcium is normal.
Nutritional agents made of Example three takes each ten people of 45,50,60,70,80 age bracket sufferers of osteoporosis face, to every
People measures bone density T value, and owner's bone density T value is added divided by total number of persons, calculates bone density T value average value, then everyone is every
The moon, patient took nutritional agents made of six hectogram embodiments three, measured bone density T value, owner's bone density T to everyone after half a year
Value is added divided by total number of persons, the average value of bone density T value after calculating half a year, and comparison discovery bone density changes, bone density T value
It is risen between -1.5 from -3, and takes and do not occur side effect in the middle.
The above shows and describes the basic principle, main features and advantages of the invention.The technology of the industry
Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this
The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes
Change and improvement all fall within the protetion scope of the claimed invention.The claimed scope of the invention by appended claims and its
Equivalent circle.
Claims (9)
1. a kind of treat the sorbefacient nutritional agents of osteoporosis, which is characterized in that be made of the raw material for including following parts by weight:
2. a kind of as described in claim 1 treat the sorbefacient nutritional agents of osteoporosis, which is characterized in that by including following
The raw material of parts by weight is made:
3. a kind of as claimed in claim 1 or 2 treat the sorbefacient nutritional agents of osteoporosis, it is characterised in that: the benefit
Bacteria-promoting agent is Bifidobacterium.
4. a kind of as claimed in claim 1 or 2 treat the sorbefacient nutritional agents of osteoporosis, it is characterised in that: described multiple
In-one nutritive powder agent is by including corn flour, brown sugar, wheat bran, water and leavening.
5. a kind of as claimed in claim 4 treat the sorbefacient nutritional agents of osteoporosis, it is characterised in that: the leavening
Including Bifidobacterium, actinomyces, saccharomycete, lactic acid bacteria be one such or a variety of mixtures.
6. a kind of prepare the method for treating the sorbefacient nutritional agents of osteoporosis as described in claim 1 to 2, feature exists
In, including the following steps:
1) crush maize is mixed to 300 mesh with wheat bran；
2) brown sugar with 100 degree boiled water disinfection and sterilization 30 minutes, it is cold to be really put into rustless steel container to 50 DEG C；
3) warm water stirring is added in leavening, and breeding expands two hours, is subsequently added in step 2) rustless steel container, expands within three hours
Big breeding, is then mixed with step 1) corn bran, and suitable water is during which added, and is put into stainless steel blender and stirs 10 points
Clock, stacking cover ten layers of white cotton fermentation at mountain type；
3) fermentation time 10 days are turned over once daily, until last day opens and completes zymotechnique；
4) drying process obtains compound nutritional pulvis after fermentation within ten days；
5) the compound nutritional pulvis of 50~80% parts by weight and the probiotics of 1~2% parts by weight, 25~30% parts by weight are taken
The treatment sorbefacient nutritional agents of osteoporosis is made in the multivitamin mixing of corn isoflavones, 1~2 parts by weight.
7. the method for the preparation treatment sorbefacient nutritional agents of osteoporosis as claimed in claim 6, it is characterised in that: described
In step 3) when fermentation, fermentation plant keeps ventilation device, and the room temperature is not less than 20 DEG C, and humidity is 70~80%.
8. the method for the preparation treatment sorbefacient nutritional agents of osteoporosis as claimed in claim 6, it is characterised in that: described
It is made in step 4) in compound nutritional pulvis and must not detect sramana's formula bacterium, will congratulates formula bacterium, staphylococcus aureus.
9. the method for the preparation treatment sorbefacient nutritional agents of osteoporosis as claimed in claim 6, it is characterised in that: described
Leavening is that Bifidobacterium, actinomyces, saccharomycete, lactic acid bacteria be one such or a variety of mixtures.
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Cited By (1)
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| CN116019843A (en) * | 2023-03-24 | 2023-04-28 | 昆明学院 | Preparation method of probiotic powder and application of probiotic powder in preparation of preparation for treating osteoporosis |
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| CN116019843A (en) * | 2023-03-24 | 2023-04-28 | 昆明学院 | Preparation method of probiotic powder and application of probiotic powder in preparation of preparation for treating osteoporosis |
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