CN109512380A - The method for making full retina dioptric topographic map based on wavefront sensing technique - Google Patents
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- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/1015—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for wavefront analysis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B3/00—Apparatus for testing the eyes; Instruments for examining the eyes
- A61B3/10—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions
- A61B3/103—Objective types, i.e. instruments for examining the eyes independent of the patients' perceptions or reactions for determining refraction, e.g. refractometers, skiascopes
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Abstract
The present invention relates to eyes optometry fields, disclose a kind of method for making full retina dioptric topographic map based on wavefront sensing technique;In existing commercialization optometry product, there is no simple and effective optometry means can high density continuously measure retinal periphery refractive status;The wavefront signals to be checked being emitted when the present invention is based on wavefront sensing techniques using Hartmann-Shack lens array and wave front aberration detector detection eyes different perspectives, the numerical value of corresponding optical parameter is calculated by Zelnick modelling again, it is converted into corresponding data matrix, dioptric topographic map is finally established by computer.It is not only that research retinal peripheral defocusing and the correlativity of eye refraction development provide strong research tool, and are conducive to the influence for research peripheral retina aberration for visual quality and promote the postoperative visual effect that the myopia laser of wave front aberration guidance is performed the operation.
Description
Technical field
The present invention relates to eyes optometrys, make full retina dioptric landform based on wavefront sensing technique more particularly to one kind
The method of figure.
Background technique
Ametropia includes myopia, long sight, astigmatism, is the most common disease of Clinical Ophthalmology outpatient service.Wherein, it is given especially with myopia
Personal, society, national bring negative effect are maximum.According to the statistics of the World Health Organization, China has become in the world with myopia
The most country of crowd.Near-sighted influence is not only personal Vision Health, also affects national enlisted in the arms, pilot's training of conscripting
The culture of large quantities of professionals such as feeding, navigation, fire-fighting, criminal investigation, therefore, ametropic prevention and treatment are most important.
Light travels to the curved surface that equiphase surface at a certain position forms and is known as wavefront, however, due to human eye be one not
Perfect optical system, such as axis oculi and optical axis is not consistent, crystalline lens density unevenness, anterior corneal surface are irregular, will lead into
The wavefront for entering or projecting human eye generates deviation, and the deviation between this ideal wavefront and actual wavefront is referred to as wave front aberration.
Wave front aberration is decomposed according to Zernike Polynomials, can be divided into low order aberration and higher order aberratons.Wherein, low order aberration include from
Traditional common optical parameter in optometry field such as burnt and astigmatism;Higher order aberratons include the forms contents such as coma, clover astigmatism more
Add complicated optical change, the relationship between optics meaning and visual performance is also still further studied to people.
Existing research thinks that retinal periphery refractive status has a major impact visual development.Such as, Ortho-K is
Myopia progression most efficient method is controlled in prior art means, one of the important hypothesis for controlling near-sighted principle is exactly cornea modeling
Shape mirror can form a circle negative-pressure suction ring on the periphery of cornea, and the optical focus on eyeball periphery is caused to fall in front of retina,
And generate the effect of myopia control.The phenomenon is referred to as ' peripheral myopic defocus '.In addition also have based on the production of this hypothesis
Frame eyeglasses, such as ' Cheng Changle ' of the production of Zeiss, Germany company, still, near-sighted control effect is close in all ages and classes, difference
But there were significant differences for control effect in visual range degree, different crowd.One of an important factor for restricting ' periphery defocus ' hypothesis research
Be exactly, in existing commercialization optometry product, there is no letter and effective optometry means can high density continuously measure retina
Peripheral refractive state.
Summary of the invention
The present invention provides a kind of methods for making full retina dioptric topographic map based on wavefront sensing technique, should be based on wave
The method that preceding sensing technology makes full retina dioptric topographic map is not only that research retinal peripheral defocusing and eye refraction are developed
Correlativity provide strong research tool, and be conducive to for research peripheral retina aberration for visual quality
Influence and promoted wave front aberration guidance myopia laser operation postoperative visual effect.
To achieve the goals above, the present invention provides a kind of based on the full retina dioptric topographic map of wavefront sensing technique production
Method, include the following steps:
1) it is lower than the opposite dark room conditions of 10 lux in intensity of illumination, the head position of fixed examinee makes examinee's
Eyes are suitable for through the core label in mirror lens head-up sighting target module at the moment;
2) wavefront signals light source sending optical signal enters examinee's pupil, and optical signal forms wavefront signals on the retina,
After the wavefront signals are by retinal reflex, outgoing forms wavefront signals to be checked again after ophthalmic refractive system, described to be checked
Wavefront signals are after multiple reflections, by being detected after Hartmann-Shack (Shack-Hartmann) lens array by wave front aberration
Device receives, and forms the lattice array distributed discrete hot spot of distortion on the wave front aberration detector, obtains corresponding picture;
3) the other labels for watching the eyes of examinee through the mirror lens at the moment in sighting target module attentively repeat to walk
Rapid process 2);
4) the wave front aberration detector horizontally rotates different angle around pupil center's line, repeats step 2) and step 3)
Process;
5) it after obtaining all pictures, reuses Harmann-Shack method and all pictures is handled, obtain wave
Preceding aberration is calculated the numerical value of optical parameter by Zelnick modelling, obtains wavefront aberration measurement;
6) according to the corresponding spatial position on the retina of each wavefront aberration measurement, each wave-front optical aberration measurement knot is established
The data matrix of fruit;
7) according to data matrix, dioptric topographic map is established with software data processing matrix by computer.
Preferably, the wave front aberration detector setting is in L-type optical arm one end, the L-type optical arm other end and rotation
Rotating motor connection, the rotating electric machine are located above eyes and the L-type optical arm can be made to horizontally rotate around pupil center's line.
Preferably, when the L-type optical arm is located at the front of eyes, and look squarely front eyes axis oculi with enter eye
When the optical signal of eyeball is in a straight line, the location of described L-type optical arm is initial position, the wave front aberration detector
The wavefront information signal to be checked of detection corresponds to the coordinate origin on the dioptric topographic map.
Preferably, the L-type optical arm is horizontal within the scope of initial position to 40 ° of nasal side and initial position to 40 ° of temporo side
Rotation.
Preferably, when the L-type optical arm is not on initial position, distortion is formed on the wave front aberration detector
Lattice array distributed discrete hot spot be ellipse arrangement image, need the horizontal diameter for stretching the image to make its conversion at this time
For the image of circular arrangement, then pass through Zelnick modelling analytical calculation.
Preferably, the sighting target module includes the multiple pictorial symbolizations being vertically arranged successively, core label, wavefront signals light
Image and macula retinae of the source on mirror lens form conjugation.
Preferably, the optical parameter includes but is not limited to each rank aberration, concave-sphere, cylindrical mirror, axial direction.
Preferably, the dioptric topographic map is three-dimensional mesh or volume rending exterior view.
Preferably, the wavefront signals to be checked that the wave front aberration detector described in the step 2) receives are reflective tight by cornea
When interfering again, it is suitable for eliminating the reflective interference of cornea using one of following three kinds of methods;
First method finely tunes the height of the L-type optical arm up and down, to avoid the reflective interference of cornea;
Second method directly abandons the wavefront signals to be checked by the reflective interference of cornea, duplicate measurements, until detecting
It is not affected by the wavefront signals to be checked of the reflective interference of cornea and replaces the wavefront signals to be checked by the reflective interference of cornea with it;
The third method, in step 5), using curve matching or the wavefront aberration data of data interpolating polishing missing.
Preferably, in the first method, on the basis of pupil center's line, the model of the L-type optical arm height adjustment
It is trapped among within pupil radium.
Through the above technical solutions, a kind of method for establishing retina dioptric topographic map provided by the invention, it being capable of big model
It encloses, the highdensity optical parameter for obtaining the upper multiple sites of human eye retina, overcomes conventional art and be difficult to a wide range of accurate point
The deficiency for analysing retinal periphery optical defocus, aberration facilitates the machine for illustrating retinal periphery optical change influence eyeball development
System, and help to be promoted the postoperative visual effect of myopia laser surgey.
Other features and advantages of the present invention further illustrate specific embodiment part below.
Detailed description of the invention
Fig. 1 is the optical principle schematic diagram of embodiment of the present invention;
Fig. 2 is the side view of Fig. 1;
Fig. 3 is the schematic diagram of L-type optical arm rotation formula in embodiment of the present invention;
Fig. 4 is the schematic diagram of coordinate system in embodiment of the present invention;
Fig. 5 is the schematic diagram that hot spot is distributed in independent rectangular area in embodiment of the present invention;
Fig. 6 is the schematic diagram that aberration slope calculates in embodiment of the present invention.
Description of symbols
1 eyes, 11 pupil center
2 wave front aberration detector, 21 Hartmann-Shack lens array
3 wavefront signals light sources 31 are with aperture partition
4 first mirror surface, 5 mirror lens
6 beam splitter, 7 first lens
8 second lens, 9 the third lens
101 L-type optical arm, 102 rotating electric machine
The other labels of 201 core label 202
301 second mirror surface, 302 third mirror surface
401 lenticule, 402 theoretical wavefront
403 actual wavefront, 404 emergent pupil surface
Specific embodiment
In order to make those skilled in the art more fully understand the present invention program, below in conjunction with attached drawing of the invention, to this hair
Technical solution in bright embodiment is clearly and completely described, it is clear that described embodiment is only used for describing and explaining this
Invention, is not intended to restrict the invention.
In the description of the present invention, it is to be understood that, term " on ", "lower", "left", "right", "front", "rear", "inner",
The orientation or positional relationship of the instructions such as "outside", "top", "bottom" is to be based on the orientation or positional relationship shown in the drawings, merely to just
In description the present invention and simplify description, rather than the device or element of indication or suggestion meaning must have a particular orientation, with
Specific orientation construction and operation, therefore be not considered as limiting the invention.
In addition, term " first ", " second " are only used for the purpose of description, it is not understood to indicate or imply relatively important
Property or implicitly indicate the quantity of indicated technical characteristic and therefore define " first ", the feature of " second " can be expressed or hidden
It include one or more features containing ground.
As shown in Figure 1, Figure 2 and Figure 3, the side of the invention that full retina dioptric topographic map is made based on wavefront sensing technique
Method includes the following steps:
1) in intensity of illumination under conditions of 10 lux opposite dark room conditions below, the head position of fixed examinee,
The core label 201 for looking squarely the eyes 1 of examinee through mirror lens 5 at the moment in sighting target module;
2) wavefront signals light source 3 emits beam, and forms a branch of directional light by the first lens 7 and with aperture partition 31, i.e.,
Optical signal, optical signal inject eyes by the multiple reflections of beam splitter 6, the first mirror surface 4 and mirror lens 5, and optical signal exists
Wavefront signals are formed on retina, wavefront signals reflect on the retina, after ophthalmic refractive system again outgoing formed it is to be checked
Wavefront signals, wavefront signals to be checked pass through mirror lens 5, the first mirror surface 4, beam splitter 6, the second lens 8, the second reflecting mirror
Face 301, third mirror surface 302, the third lens 8 and Hartmann-Shack lens array 21 are connect by wave front aberration detector 2
It receives, forms the lattice array distributed discrete hot spot of distortion on wave front aberration detector 2, obtain corresponding picture;
3) the other labels 202 for watching the eyes 1 of examinee through mirror lens 5 at the moment in sighting target module attentively repeat
The process of step 2);
4) wave front aberration detector 2 horizontally rotates different angle around the rotation center 11 of eyes 1, repeats step 2) and step
3) process;Wherein, wave front aberration detector 2 is mounted in 101 end of L-type optical arm, 101 other end of L-type optical arm with
Rotating electric machine 102 connects, rotating electric machine 102 is located at 1 top of eyes and L-type optical arm 101 can be made horizontal around pupil center 11
Rotation, i.e., wave front aberration detector 2 can also horizontally rotate around pupil center 11;
5) it after obtaining all pictures, reuses Harmann-Shack method and all pictures is handled, obtain wave
Preceding aberration is calculated the numerical value of optical parameter by Zelnick modelling, obtains wavefront aberration measurement;Optical parameter
Numerical value includes but is not limited to each rank aberration, concave-sphere, cylindrical mirror and axial direction;
6) according to the corresponding spatial position on the retina of each wavefront aberration measurement, each wave-front optical aberration measurement knot is established
The data matrix of fruit;
7) according to data matrix, by computer with surf, surface of MATLAB software, surfc, surfl, mesh,
Meshz, meshc, contour, waterfall or ribbon command process data matrix establish dioptric topographic map.
Wherein, when L-type optical arm 101 is located at the front of eyes 1, and the axis oculi and wavefront signals of the eyes in head-up front
When the optical signal of the injection eyes 1 of light source 3 is in a straight line, the location of L-type optical arm 101 is set as initial position, this
When be initial time, the wavefront signals to be checked that wave front aberration detector 2 detects correspond to the position definition on dioptric topographic map
For (0,0), (0,0) here is the preceding bidimensional of dioptric topographic map, and the third dimension is exactly optics of the dioptric topographic map in this site
The numerical value of parameter;L-type optical arm 101 can be from initial position to 40 ° of nasal side and initial position to horizontal within the scope of 40 ° of temporo side
Rotation, to drive wave front aberration detector 2 around pupil center 11 from initial position to 40 ° of nasal side and initial position to temporo side
Horizontally rotate within the scope of 40 °, detection eyes 1 watch pictorial symbolization (including the core label 201 of the different location in sighting target module attentively
With other labels 202) when wavefront signals to be checked, establish dioptric topographic map for computer and data be provided;Sighting target module includes hanging down
The multiple pictorial symbolizations being directly arranged successively, core label, image and macula retinae of the wavefront signals light source on mirror lens
Form conjugation (three is located in a straight line);When L-type optical arm 101 leaves initial position, the formation of wave front aberration detector 2
The lattice array distributed discrete hot spot of distortion is the image of ellipse arrangement, and the horizontal diameter for stretching image is needed to make its conversion at this time
For circle, then wavefront analyzed by Zelnick modelling.
In step 5), all pictures are handled using Harmann-Shack method, obtain the process of wave front aberration such as
Under:
Generally speaking, the aberration in each site on exit pupil plane 404 is first calculated, is then intended with Zernike Polynomials
The aberration in each site is closed as a result, obtaining every Zelnick coefficient, Zelnick coefficient is exactly one kind for expressing aberration
Mode;
1. calculating the actual facula mass center of each square region on ccd detector (wave front detector)
Referring to Fig. 4 and Fig. 5, the distorted wavefront (wavefront signals to be checked) from human eye retina is through Hartmann-Shack
Lens array can form a series of blur spots on ccd detector, each hot spot is all located at an independent rectangular area
It is interior, the mass center of each hot spot is calculated with following formula:
In formula, discrete parameter i and j respectively represent the coordinate of pixel of the ccd detector in x-axis and y-axis, and I (i, j) is the
Light spot energy on i row jth column, SxAnd SyFor the spacing on ccd detector between x-axis and y-axis;(imin, jmin) indicate independent square
The lower left corner in shape region, (imax, jmax) indicate separate rectangular region the upper right corner;
2. calculating actual facula mass center and the position side of theoretical facula mass center being poor
After the mass center for having calculated each region, according to the coordinate (x of standardized centroidr, yr), you can get it, and position side is poor
(Δ x, Δ y):
Δ x=xc-xr, Δ y=yc-yr
3. deriving wavefront slope by geometric optics
Referring to Fig. 6, what Fig. 6 was indicated is the geometry grade of the actual wavefront 403 and theoretical wavefront 402 that project from lenticule 401
Schematic diagram;F is the distance that lenticule 401 arrives ccd detector, and Δ y is that the side of wavefront on the y axis is poor, when practical corrugated 403 and reason
When thinking wavefront 402 tangent at the exit pupil plane 404 of optical system or intersection, the optical path difference between two corrugateds is indicated with W, as wave
Preceding aberration, R are the light path of actual wavefront;
As seen from the figure
R2=Δ y2+(R-W(Δy))2
Slope of the wavefront on y-axis component are as follows:
4. calculating the wave front aberration in each separate rectangular region by position side difference
From 3.
The then aberration in each separate rectangular region are as follows:
5. Zernike Polynomials
After the aberration for calculating each isolated area of pupil, the wavefront reconstruction in adaptive optical theory need to be used theoretical
To describe the aberration of entire human eye;The method for the description aberration that the present invention uses is for Zelnick (Zemike) modelling, i.e., logical
Zernike Polynomials are crossed to be fitted human eye aberration;Be defined in unit circle one group of the essence of Zernike Polynomials is orthogonal
Base theoretically can have infinite multiple basic functions before describing a complex wave, and clinically the most commonly used is preceding 5 rank (21);
Under polar coordinates, the polynomial expression formula of Zernike are as follows:
In formula,To normalize item,For radial item, M (m θ) is azimuth, and radial parameter ρ is nondimensional
Real number, value range are 0~1.0, indicate aperture center to the radial away from r, expression formula of a bit are as follows:
A is the radius value in aperture;
In formula, n represents radial order, and m represents orientation order, it is desirable that n and | m | while being odd number or even number;
Normalize itemExpression formula are as follows:
Wherein, as m=0, δ0, m=1;As m ≠ 0, δ0, m=0;
Radial itemExpression formula are as follows:
When radial order n is even number (odd number),It will only include the even order terms (odd item) of ρ
The expression formula of azimuth M (m θ) are as follows:
M (m θ)=cos (m θ) is if m >=0
M (m θ)=sin (| m | θ) if m < 0
It is given directly below ten before Zernike Polynomials polar form:
Dioptric topographic map is located in three-dimensional space, and manifestation mode can be three-dimensional mesh, volume rending exterior view;Institute
The X-axis for stating three-dimensional mesh or volume rending exterior view indicates that line I and line II are formed by angle in the horizontal direction, institute
The Y-axis for stating three-dimensional mesh or volume rending exterior view indicates that line I and line II are formed by angle in vertical orientations, institute
The Z axis for stating three-dimensional mesh or volume rending exterior view indicates light of the dioptric system of entire eyeball on corresponding retina site
Learn the numerical values recited of parameter;Wherein, line I is the line of pupil center and macula retinae, and line II is pupil center and view
Nethike embrane is detected the line in site.
The present invention obtains at this time it is possible that the situation that the reflective wavefront signals to be checked returned with retina of cornea are overlapped
Wavefront signals to be checked by by reflective severe jamming, should be abandoned;Three kinds of methods can be used to solve the above problems: side
Method 1, directly (centered on pupil, the range adjusted up and down is no more than pupil half to the height of fine tuning L-type optical arm 101 up and down
Diameter), it is reflective can directly to avoid cornea;Method 2, since there are many measurement point position of the invention, (mode used by method 1 is only fitted
For a certain fixed measuring point, the horizontal extent of measurement is 80 °, the quantity of measurement point position depend on motor velocity of rotation and
The look-in frequency of wave front aberration detector), qualified wavefront signals to be checked can be obtained by being unable to ensure each measurement point, therefore,
It need to directly abandon the incongruent wavefront signals to be checked for belonging to above situation, then duplicate measurements, by measuring twice or repeatedly,
Until incongruent wavefront signals to be checked of some point of certain measurement meeting by the same point of another one-shot measurement
Wavefront signals to be checked replace, thus polishing missing data, wherein the light spot energy checked according to ccd detector;When energy height
In theory setting value, (size of this setting value depends on the power of wavefront signals, and the hole of the diaphragm to adjust illumination
Diameter size) when, it is believed that there is the interference reflective from cornea, that is, what is detected is incongruent wavefront signals to be checked;Method 3,
Device operator veteran for one, duplicate measurements can guarantee that shortage of data, needle does not occur in about 99% site twice
To the deletion segment of remaining only a few, it can be used for polishing missing data there are two types of method: removing at optic papilla, with human eye Huang
Spot is separation, and retina is respectively a continuously smooth curved surface in the cross section of nasal side and temporo side, therefore can pass through mathematical function
Polishing missing data the case where for measuring limit site (such as position of 40 ° of 40 ° of nasal side or temporo side) consecutive miss, can be used
The method polishing missing data of curve matching, for the data of non-limit site interruption missing, the method that data interpolating can be used
Polishing missing data, such as 3 Hermite interpolations and 3 spline interpolations, for example, when detector rotates to some angle and occurs
When the reflective interference of serious cornea, the wave front aberration of this position can not be measured, and utilize curve matching or data difference
The missing data of the wave front aberration of this position of the method polishing of value.
It is described the prefered embodiments of the present invention in detail above in conjunction with attached drawing, still, the present invention is not limited thereto.At this
, can be with various simple variants of the technical solution of the present invention are made in the range of the technology design of invention, including each particular technique
Feature is combined in any suitable manner.In order to avoid unnecessary repetition, the present invention is to various combinations of possible ways
No further explanation will be given.But it should also be regarded as the disclosure of the present invention for these simple variants and combination, belongs to the present invention
Protection scope.
Claims (10)
1. a kind of method for making full retina dioptric topographic map based on wavefront sensing technique, which is characterized in that including walking as follows
It is rapid:
1) it is lower than the opposite dark room conditions of 10lux in intensity of illumination, the head position of fixed examinee keeps the eyes of examinee suitable
In through the core label in mirror lens head-up sighting target module at the moment;
2) wavefront signals light source sending optical signal enters examinee's pupil, and optical signal forms wavefront signals on the retina, described
After wavefront signals are by retinal reflex, outgoing forms wavefront signals to be checked, the wavefront to be checked again after ophthalmic refractive system
Signal is after multiple reflections, by being received after Hartmann-Shack lens array by wave front aberration detector, in the wavefront
The lattice array distributed discrete hot spot that distortion is formed on aberration detector, obtains corresponding picture;
3) the other labels for watching the eyes of examinee through the mirror lens at the moment in sighting target module attentively repeat step 2)
Process;
4) the wave front aberration detector horizontally rotates different angle around pupil center's line, repeats the mistake of step 2) and step 3)
Journey;
5) it after obtaining all pictures, reuses Harmann-Shack method and all pictures is handled, obtain wavefront picture
Difference is calculated the numerical value of optical parameter by Zelnick modelling, obtains wavefront aberration measurement;
6) according to the corresponding spatial position on the retina of each wavefront aberration measurement, each wavefront aberration measurement is established
Data matrix;
7) according to data matrix, dioptric topographic map is established with software data processing matrix by computer.
2. the method according to claim 1 for making full retina dioptric topographic map based on wavefront sensing technique, feature
It is, the wave front aberration detector is arranged in L-type optical arm one end, and the L-type optical arm other end is connect with rotating electric machine,
The rotating electric machine is located above eyes and the L-type optical arm can be made to horizontally rotate around pupil center's line.
3. the method according to claim 2 for making full retina dioptric topographic map based on wavefront sensing technique, feature
It is, when the L-type optical arm is located at the front of eyes, and the axis oculi of the eyes in head-up front and the optical signal for entering eyes
When in a straight line, the location of described L-type optical arm is initial position, and the wave front aberration detector detects to be checked
Wavefront signals correspond to the coordinate origin on the dioptric topographic map.
4. the method according to claim 3 for making full retina dioptric topographic map based on wavefront sensing technique, feature
It is, the L-type optical arm horizontally rotates within the scope of initial position to 40 ° of nasal side and initial position to 40 ° of temporo side.
5. the method according to claim 3 for making full retina dioptric topographic map based on wavefront sensing technique, feature
It is, when the L-type optical arm is not on initial position, forms the lattice array point of distortion on the wave front aberration detector
Cloth discrete light spot is the image of ellipse arrangement, needs the horizontal diameter for stretching the image that it is made to be converted into circular arrangement at this time
Image, then pass through Zelnick modelling analytical calculation.
6. according to any one of claim 1 to 5 make full retina dioptric topographic map based on wavefront sensing technique
Method, which is characterized in that the sighting target module includes the multiple pictorial symbolizations being vertically arranged successively, core label, wavefront signals
Image and macula retinae of the light source on mirror lens form conjugation.
7. according to any one of claim 1 to 5 make full retina dioptric topographic map based on wavefront sensing technique
Method, which is characterized in that the optical parameter includes but is not limited to each rank aberration, concave-sphere, cylindrical mirror, axial direction.
8. according to any one of claim 1 to 5 make full retina dioptric topographic map based on wavefront sensing technique
Method, which is characterized in that the dioptric topographic map is three-dimensional mesh or volume rending exterior view.
9. the method according to claim 1 for making full retina dioptric topographic map based on wavefront sensing technique, feature
It is, when reflective by the cornea severe jamming of the wavefront signals to be checked that the wave front aberration detector described in the step 2) receives,
Suitable for eliminating the reflective interference of cornea using one of following three kinds of methods;
First method finely tunes the height of the L-type optical arm up and down, to avoid the reflective interference of cornea;
Second method, directly abandons the wavefront signals to be checked by the reflective interference of cornea, duplicate measurements, until detect not by
To the reflective interference of cornea wavefront signals to be checked and replace the wavefront signals to be checked by the reflective interference of cornea with it;
The third method, in step 5), using curve matching or the wavefront aberration data of data interpolating polishing missing.
10. the method according to claim 9 for making full retina dioptric topographic map based on wavefront sensing technique, feature
It is, in the first method, on the basis of pupil center's line, the range of the L-type optical arm height adjustment is in pupil half
Within diameter.
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Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030020872A1 (en) * | 1998-08-19 | 2003-01-30 | Junzhong Liang | Apparatus and method for measuring vision defects of a human eye |
EP1295559A2 (en) * | 2001-09-21 | 2003-03-26 | Carl Zeiss Ophthalmic Systems, Inc. | Method and apparatus for measuring optical aberrations of an eye |
CN1684627A (en) * | 2002-09-25 | 2005-10-19 | 博士伦公司 | Wavefront-generated custom ophthalmic surfaces |
CN101224103A (en) * | 2008-02-01 | 2008-07-23 | 上海理工大学 | Human eye aberration measuring device and method thereof |
CN101259009A (en) * | 2008-03-26 | 2008-09-10 | 中国科学院光电技术研究所 | Cornea topographic map measurer |
CN101732029A (en) * | 2009-12-04 | 2010-06-16 | 沈阳理工大学 | Wave-front aberration-based vision tester |
CN102914879A (en) * | 2012-11-06 | 2013-02-06 | 天津宇光光学公司 | Design method of free-form surface glasses based on wave-front technology |
CN103153170A (en) * | 2010-10-15 | 2013-06-12 | 穆尔西亚大学 | Instrument for rapid measurement of the optical properties of the eye across the whole field of vision |
CN103338693A (en) * | 2010-11-18 | 2013-10-02 | I-光学有限责任公司 | Color coded topographer and method of determining a mathematical model of a corneal surface |
CN103491856A (en) * | 2011-02-24 | 2014-01-01 | 透明医疗体系公司 | Measurement/display/record/playback of wavefront data for use in vision correction procedures |
CN105283118A (en) * | 2013-06-10 | 2016-01-27 | 埃西勒国际通用光学公司 | Method for determining wave-front aberration data of a to-be-tested optical system |
-
2018
- 2018-11-02 CN CN201811302579.1A patent/CN109512380A/en active Pending
Patent Citations (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20030020872A1 (en) * | 1998-08-19 | 2003-01-30 | Junzhong Liang | Apparatus and method for measuring vision defects of a human eye |
EP1295559A2 (en) * | 2001-09-21 | 2003-03-26 | Carl Zeiss Ophthalmic Systems, Inc. | Method and apparatus for measuring optical aberrations of an eye |
CN1684627A (en) * | 2002-09-25 | 2005-10-19 | 博士伦公司 | Wavefront-generated custom ophthalmic surfaces |
CN101224103A (en) * | 2008-02-01 | 2008-07-23 | 上海理工大学 | Human eye aberration measuring device and method thereof |
CN101259009A (en) * | 2008-03-26 | 2008-09-10 | 中国科学院光电技术研究所 | Cornea topographic map measurer |
CN101732029A (en) * | 2009-12-04 | 2010-06-16 | 沈阳理工大学 | Wave-front aberration-based vision tester |
CN103153170A (en) * | 2010-10-15 | 2013-06-12 | 穆尔西亚大学 | Instrument for rapid measurement of the optical properties of the eye across the whole field of vision |
CN103338693A (en) * | 2010-11-18 | 2013-10-02 | I-光学有限责任公司 | Color coded topographer and method of determining a mathematical model of a corneal surface |
CN103491856A (en) * | 2011-02-24 | 2014-01-01 | 透明医疗体系公司 | Measurement/display/record/playback of wavefront data for use in vision correction procedures |
CN102914879A (en) * | 2012-11-06 | 2013-02-06 | 天津宇光光学公司 | Design method of free-form surface glasses based on wave-front technology |
CN105283118A (en) * | 2013-06-10 | 2016-01-27 | 埃西勒国际通用光学公司 | Method for determining wave-front aberration data of a to-be-tested optical system |
Non-Patent Citations (4)
Title |
---|
中国人民解放军总后勤部卫生部: "《医疗护理技术操作常规》", 31 August 1987, 人民军医出版社 * |
李耀宇: "《眼科手术新进展—眼波前引导的屈光手术学》", 31 January 2009, 人民军医出版社 * |
胡振宏: "基于MFC的角膜地形图仪软件设计与像差分析", 《中国优秀硕士学位论文全文数据库 工程科技II辑》 * |
莫雷,温忠麟,陈彩琦: "《心理学研究方法》", 30 September 2007, 广东教育高等出版社 * |
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