CN109464620A - A kind of Whelk-eliminating paste and preparation method thereof containing refined coptis extract - Google Patents
A kind of Whelk-eliminating paste and preparation method thereof containing refined coptis extract Download PDFInfo
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- CN109464620A CN109464620A CN201811331056.XA CN201811331056A CN109464620A CN 109464620 A CN109464620 A CN 109464620A CN 201811331056 A CN201811331056 A CN 201811331056A CN 109464620 A CN109464620 A CN 109464620A
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- mass parts
- whelk
- coptis extract
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- eliminating paste
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- 235000002991 Coptis groenlandica Nutrition 0.000 title claims abstract description 43
- 239000000284 extract Substances 0.000 title claims abstract description 43
- 238000002360 preparation method Methods 0.000 title claims abstract description 18
- 241000218202 Coptis Species 0.000 title 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims abstract description 60
- 244000247747 Coptis groenlandica Species 0.000 claims abstract description 42
- 239000002994 raw material Substances 0.000 claims abstract description 29
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 28
- 241000205585 Aquilegia canadensis Species 0.000 claims abstract description 20
- CDQSJQSWAWPGKG-UHFFFAOYSA-N butane-1,1-diol Chemical compound CCCC(O)O CDQSJQSWAWPGKG-UHFFFAOYSA-N 0.000 claims abstract description 19
- 240000004371 Panax ginseng Species 0.000 claims abstract description 17
- 235000002789 Panax ginseng Nutrition 0.000 claims abstract description 17
- 239000010231 banlangen Substances 0.000 claims abstract description 17
- 235000008434 ginseng Nutrition 0.000 claims abstract description 17
- 241001499733 Plantago asiatica Species 0.000 claims abstract description 16
- 239000008213 purified water Substances 0.000 claims abstract description 16
- 235000005187 Taraxacum officinale ssp. officinale Nutrition 0.000 claims abstract description 15
- 229940099259 vaseline Drugs 0.000 claims abstract description 15
- 241000362909 Smilax <beetle> Species 0.000 claims abstract description 12
- 239000000843 powder Substances 0.000 claims abstract description 12
- 240000001949 Taraxacum officinale Species 0.000 claims abstract description 10
- 239000003814 drug Substances 0.000 claims abstract description 7
- 238000009835 boiling Methods 0.000 claims description 26
- 239000012530 fluid Substances 0.000 claims description 18
- 239000006071 cream Substances 0.000 claims description 14
- 238000002156 mixing Methods 0.000 claims description 11
- 238000001914 filtration Methods 0.000 claims description 9
- 239000000203 mixture Substances 0.000 claims description 9
- 238000001704 evaporation Methods 0.000 claims description 8
- 230000008020 evaporation Effects 0.000 claims description 8
- 239000007788 liquid Substances 0.000 claims description 8
- 239000012528 membrane Substances 0.000 claims description 6
- 241000605422 Asparagus asparagoides Species 0.000 claims description 5
- 241000245665 Taraxacum Species 0.000 claims description 5
- 239000011521 glass Substances 0.000 claims description 5
- 238000007654 immersion Methods 0.000 claims description 5
- 238000000108 ultra-filtration Methods 0.000 claims description 5
- 239000000463 material Substances 0.000 claims description 4
- 240000000249 Morus alba Species 0.000 claims description 3
- 235000008708 Morus alba Nutrition 0.000 claims description 3
- 238000013019 agitation Methods 0.000 claims description 3
- 238000010411 cooking Methods 0.000 claims description 3
- 239000006260 foam Substances 0.000 claims description 3
- 239000007787 solid Substances 0.000 claims description 3
- 239000004094 surface-active agent Substances 0.000 claims description 3
- 239000000706 filtrate Substances 0.000 claims 1
- 241000700647 Variola virus Species 0.000 abstract description 18
- 230000000694 effects Effects 0.000 abstract description 11
- 230000000840 anti-viral effect Effects 0.000 abstract description 7
- 238000001035 drying Methods 0.000 abstract description 7
- 238000000034 method Methods 0.000 abstract description 5
- 231100000614 poison Toxicity 0.000 abstract description 4
- 230000008569 process Effects 0.000 abstract description 4
- 239000003507 refrigerant Substances 0.000 abstract description 4
- 239000003440 toxic substance Substances 0.000 abstract description 4
- 238000009792 diffusion process Methods 0.000 abstract description 3
- 229940079593 drug Drugs 0.000 abstract description 3
- 230000003255 anti-acne Effects 0.000 description 4
- 230000000857 drug effect Effects 0.000 description 3
- 208000002874 Acne Vulgaris Diseases 0.000 description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 2
- 206010000496 acne Diseases 0.000 description 2
- 244000025254 Cannabis sativa Species 0.000 description 1
- 208000017701 Endocrine disease Diseases 0.000 description 1
- 208000003251 Pruritus Diseases 0.000 description 1
- 206010040844 Skin exfoliation Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 230000007423 decrease Effects 0.000 description 1
- 230000037213 diet Effects 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 208000030172 endocrine system disease Diseases 0.000 description 1
- 230000036541 health Effects 0.000 description 1
- WGCNASOHLSPBMP-UHFFFAOYSA-N hydroxyacetaldehyde Natural products OCC=O WGCNASOHLSPBMP-UHFFFAOYSA-N 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 230000000638 stimulation Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/90—Smilacaceae (Catbrier family), e.g. greenbrier or sarsaparilla
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/19—Acanthaceae (Acanthus family)
- A61K36/195—Strobilanthes
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/31—Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
- A61K36/315—Isatis, e.g. Dyer's woad
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/68—Plantaginaceae (Plantain Family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/46—Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Biotechnology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention discloses a kind of Whelk-eliminating paste and preparation method thereof containing refined coptis extract, the Whelk-eliminating paste includes following raw material and its weight fraction: refined coptis extract is 5-15 mass parts；Glycerol is 10-15 mass parts；Butanediol is 5-12 mass parts；Pearl powder is 3-8 mass parts；Smilax is 2-5 mass parts；Dandelion is 3-4 mass parts；1-2 mass parts of Korean ginseng；Asiatic plantain is 3-6 mass parts；Honeysuckle is 2-7 mass parts；Radix Isatidis is 3-6 mass parts；Vaseline is 0.5-1 mass parts and appropriate purified water.The addition that the present invention passes through refined coptis extract, Whelk-eliminating paste can be effectively allowed to have effects that heat-clearing and damp-drying drug and removing toxic substances, accelerate the speed that patient's small pox is dispelled, there is the probability festered in the small pox for reducing patient, by the addition of honeysuckle, it can effectively allow Whelk-eliminating paste that there is antiviral and refrigerant effect, avoid the phenomenon that small pox infects, the probability for reducing small pox diffusion, improves the comfort in Whelk-eliminating paste use process.
Description
Technical field
The present invention relates to Whelk-eliminating paste technical field, specially a kind of Whelk-eliminating paste and preparation method thereof containing refined coptis extract.
Background technique
Different age and endocrine disorder, undesirable work and rest habit do not notice that personal health, diet are not advised
Rule, body immunity decline, life stress is excessive, kidney-yin deficiency etc. can all cause the growth of small pox, however anti-acne on the market
The good and bad jumbled together for product, and really effective fewer and fewer, scientific and effective product for resolving poxes is still market in urgent need, currently on the market big portion
The Eradicates acne cream or Eradicates acne effect divided is too fast, but this huge stimulation being generally accompanied with to skin, and small pox skin is natively
Very sensitive, so that skin peeling, doing, many ill symptoms of itching, the small poxs such as many people do not have also disappear down and can not endure
Simultaneous phenomenon can not adhere in turn using or some effects do not have yet.
Currently, there is also the places of some shortcomings for existing Whelk-eliminating paste, such as；Existing Whelk-eliminating paste is clear by not having
The effect of hot eliminating dampness and removing toxic substances, has slowed down the speed that patient's small pox is dispelled, and festering occurs in the small pox for improving patient to expand with small pox
Scattered probability, and Whelk-eliminating paste cannot be allowed with the phenomenon that antiviral and refrigerant effect, small pox is easy to appear infection, it reduces
Comfort in Whelk-eliminating paste use process.
Summary of the invention
The purpose of the present invention is to provide a kind of Whelk-eliminating paste and preparation method thereof containing refined coptis extract, solves background skill
The problem of proposed in art.
To achieve the above object, the invention provides the following technical scheme: a kind of Whelk-eliminating paste containing refined coptis extract, including with
Lower raw material and its weight fraction: refined coptis extract is 5-15 mass parts；Glycerol is 10-15 mass parts；Butanediol is 5-12 matter
Measure part；Pearl powder is 3-8 mass parts；Smilax is 2-5 mass parts；Dandelion is 3-4 mass parts；1-2 quality of Korean ginseng
Part；Asiatic plantain is 3-6 mass parts；Honeysuckle is 2-7 mass parts；Radix Isatidis is 3-6 mass parts；Vaseline is 0.5-1 matter
Measure part and appropriate purified water.
As a kind of preferred embodiment of the invention, the Whelk-eliminating paste containing refined coptis extract, including following raw material
And its weight fraction: glycerol is 11 mass parts；Butanediol is 7 mass parts；Pearl powder is 5 mass parts；Smilax is 3 mass parts；
Dandelion is 4 mass parts；2 mass parts of Korean ginseng；Asiatic plantain is 4 mass parts；Honeysuckle is 6 mass parts；Radix Isatidis is 5g mass
Part；Vaseline is 0.5 mass parts and appropriate purified water.
As a kind of preferred embodiment of the invention, the Whelk-eliminating paste containing refined coptis extract, including following raw material
And its weight fraction: refined coptis extract is 8 mass parts；Glycerol is 11 mass parts；Butanediol is 7 mass parts；Pearl powder is 5 mass
Part；Smilax is 3 mass parts；Dandelion is 4 mass parts；2 mass parts of Korean ginseng；Asiatic plantain is 4 mass parts；Honeysuckle is 6 matter
Measure part；Radix Isatidis is 5g mass parts；Vaseline is 0.5 mass parts and appropriate purified water.
As a kind of preferred embodiment of the invention, the preparation method of the Whelk-eliminating paste containing refined coptis extract, system
It is standby that steps are as follows:
A. above-mentioned raw materials are weighed according to parts by weight；
B. after the completion of step a, then smilax, dandelion, Korean ginseng, Asiatic plantain, honeysuckle and Radix Isatidis be put into
1-2h is impregnated in water, then the raw material after immersion is put into boiling vessel again and carries out boiling, and temperature when boiling is 90-
100 DEG C, the time of boiling is 1-2h；
C. after the completion of step b, then well-done medical fluid is put into filter and is filtered processing, mixed liquor is made
A；
D. after the completion of step c, weighed refined coptis extract, glycerol and butanediol are put into mixer, are added
Suitable purified water is mixed, and then mixed liquor A is added in mixer again and carries out mixed processing with raw material, and mixing is made
Object B；
E. after the completion of step d, then the mixture B being made staticly settled, with 4 layers filtered through gauze 3 times, then will filter
Liquid is placed on to decoct in small fire and be concentrated by evaporation, and the vaseline of its weight 1/10th is added in the medical fluid of paste, then use small fire
It decocts and is stirred continuously completion and receive cream, cream is dispensed into glass container, Whelk-eliminating paste completes.
As a kind of preferred embodiment of the invention, material cooking Shi Xianyong high fire is decocted to boiling again in the step b
Changing small fire, removal surfactant foam is stirred while decocting, filters to take out medical fluid after boiling 1 hour, the dregs of a decoction add water to decoct again, and altogether repeatedly three
It is secondary.
As a kind of preferred embodiment of the invention, using ultrafiltration membrane when the step c Chinese medicine liquid filtration treatment
It is filtered, filtering carries out in three times, will ultrafiltration membrane be replaced or be cleaned after filtering each time.
As a kind of preferred embodiment of the invention, when refined coptis extract, glycerol and butanediol mix in the step d
Temperature be 30-40 DEG C, the mixed time is 10-20min, and revolving speed when mixing is 500-750r/min, and mixed liquor A adds
Enter into mixer when carrying out mixed processing with raw material, temperature is 45-50 DEG C, and the mixed time is 30-50min, when mixing
Revolving speed be 800-1100r/min.
It is decocted as a kind of preferred embodiment of the invention, in the step e and needs constantly agitation medicine when being concentrated by evaporation
Liquid takes the medical fluid of concentration to drip in drying on mulberry paper, to drip around cream not while hot when the content in pot becomes semi-solid state
Water breakthrough mark is degree.
Compared with prior art, beneficial effects of the present invention are as follows:
The present invention can effectively allow Whelk-eliminating paste to have effects that heat-clearing and damp-drying drug and removing toxic substances by the addition of refined coptis extract,
The speed that patient's small pox is dispelled is accelerated, the probability festered occurs in the small pox for reducing patient, and by the addition of honeysuckle, can have
Effect allows Whelk-eliminating paste to have antiviral and refrigerant effect, avoids the phenomenon that small pox infects, and reduces small pox diffusion
Probability improves the comfort in Whelk-eliminating paste use process.
Detailed description of the invention
Upon reading the detailed description of non-limiting embodiments with reference to the following drawings, other feature of the invention,
Objects and advantages will become more apparent upon:
Fig. 1 is a kind of flow chart of the preparation method of the Whelk-eliminating paste containing refined coptis extract of the present invention.
Specific embodiment
Following will be combined with the drawings in the embodiments of the present invention, and technical solution in the embodiment of the present invention carries out clear, complete
Site preparation description, it is clear that described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.
Referring to Fig. 1, the present invention provides a kind of technical solution: a kind of Whelk-eliminating paste containing refined coptis extract, including following original
Material and its weight fraction: refined coptis extract is 5-15 mass parts；Glycerol is 10-15 mass parts；Butanediol is 5-12 mass parts；
Pearl powder is 3-8 mass parts；Smilax is 2-5 mass parts；Dandelion is 3-4 mass parts；1-2 mass parts of Korean ginseng；Vehicle
Preceding grass is 3-6 mass parts；Honeysuckle is 2-7 mass parts；Radix Isatidis is 3-6 mass parts；Vaseline be 0.5-1 mass parts and
Appropriate purified water.
Further, the Whelk-eliminating paste containing refined coptis extract, including following raw material and its weight fraction: glycerol is 11 matter
Measure part；Butanediol is 7 mass parts；Pearl powder is 5 mass parts；Smilax is 3 mass parts；Dandelion is 4 mass parts；Korean ginseng 2
Mass parts；Asiatic plantain is 4 mass parts；Honeysuckle is 6 mass parts；Radix Isatidis is 5g mass parts；Vaseline is 0.5 mass parts and fits
Measure purified water.
Further, the Whelk-eliminating paste containing refined coptis extract, including following raw material and its weight fraction: refined coptis extract
For 8 mass parts；Glycerol is 11 mass parts；Butanediol is 7 mass parts；Pearl powder is 5 mass parts；Smilax is 3 mass parts；Pu Gong
English is 4 mass parts；2 mass parts of Korean ginseng；Asiatic plantain is 4 mass parts；Honeysuckle is 6 mass parts；Radix Isatidis is 5g mass parts；It is all
Intellectual circle is 0.5 mass parts and appropriate purified water.
Further, the preparation method of the Whelk-eliminating paste containing refined coptis extract, preparation step are as follows:
A. above-mentioned raw materials are weighed according to parts by weight；
B. after the completion of step a, then smilax, dandelion, Korean ginseng, Asiatic plantain, honeysuckle and Radix Isatidis be put into
1-2h is impregnated in water, then the raw material after immersion is put into boiling vessel again and carries out boiling, and temperature when boiling is 90-
100 DEG C, the time of boiling is 1-2h；
C. after the completion of step b, then well-done medical fluid is put into filter and is filtered processing, mixed liquor is made
A；
D. after the completion of step c, weighed refined coptis extract, glycerol and butanediol are put into mixer, are added
Suitable purified water is mixed, and then mixed liquor A is added in mixer again and carries out mixed processing with raw material, and mixing is made
Object B；
E. after the completion of step d, then the mixture B being made staticly settled, with 4 layers filtered through gauze 3 times, then will filter
Liquid is placed on to decoct in small fire and be concentrated by evaporation, and the vaseline of its weight 1/10th is added in the medical fluid of paste, then use small fire
It decocts and is stirred continuously completion and receive cream, cream is dispensed into glass container, Whelk-eliminating paste completes.
Further, in the step b material cooking Shi Xianyong high fire decoct to boiling change small fire again, stirred while decocting
Except surfactant foam, medical fluid is filtered to take out after boiling 1 hour, the dregs of a decoction add water to decoct again, altogether repeatedly for three times.
Further, be filtered when the step c Chinese medicine liquid filtration treatment using ultrafiltration membrane, filtering in three times into
Ultrafiltration membrane will be replaced or be cleaned after filtering each time by row.
Further, temperature when refined coptis extract, glycerol and butanediol mix in the step d is 30-40 DEG C, mixing
Time be 10-20min, revolving speed when mixing is 500-750r/min, and mixed liquor A is added in mixer and raw material carries out
When mixed processing, temperature is 45-50 DEG C, and the mixed time is 30-50min, and revolving speed when mixing is 800-1100r/min.
Further, it is decocted in the step e and needs constantly agitation medical fluid when being concentrated by evaporation, when the content in pot becomes half
It takes the medical fluid of concentration to drip on dry mulberry paper when solid state while hot, loses water mark around cream to drip as degree.
Embodiment one
The Whelk-eliminating paste containing refined coptis extract, including following raw material and its weight fraction: glycerol is 11 mass parts；Fourth
Glycol is 7 mass parts；Pearl powder is 5 mass parts；Smilax is 3 mass parts；Dandelion is 4 mass parts；2 mass parts of Korean ginseng；
Asiatic plantain is 4 mass parts；Honeysuckle is 6 mass parts；Radix Isatidis is 5g mass parts；Vaseline is 0.5 mass parts and appropriate purifying
Water.
Preparation step is as follows:
A. above-mentioned raw materials are weighed according to parts by weight；
B. after the completion of step a, then smilax, dandelion, Korean ginseng, Asiatic plantain, honeysuckle and Radix Isatidis be put into
1-2h is impregnated in water, then the raw material after immersion is put into boiling vessel again and carries out boiling, and temperature when boiling is 90-
100 DEG C, the time of boiling is 1-2h；
C. after the completion of step b, then well-done medical fluid is put into filter and is filtered processing, mixed liquor is made
A；
D. after the completion of step c, weighed refined coptis extract, glycerol and butanediol are put into mixer, are added
Suitable purified water is mixed, and then mixed liquor A is added in mixer again and carries out mixed processing with raw material, and mixing is made
Object B；
E. after the completion of step d, then the mixture B being made staticly settled, with 4 layers filtered through gauze 3 times, then will filter
Liquid is placed on to decoct in small fire and be concentrated by evaporation, and the vaseline of its weight 1/10th is added in the medical fluid of paste, then use small fire
It decocts and is stirred continuously completion and receive cream, cream is dispensed into glass container, Whelk-eliminating paste completes.
Embodiment two
The Whelk-eliminating paste containing refined coptis extract, including following raw material and its weight fraction: refined coptis extract is 8 mass
Part；Glycerol is 11 mass parts；Butanediol is 7 mass parts；Pearl powder is 5 mass parts；Smilax is 3 mass parts；Dandelion is 4 matter
Measure part；2 mass parts of Korean ginseng；Asiatic plantain is 4 mass parts；Honeysuckle is 6 mass parts；Radix Isatidis is 5g mass parts；Vaseline is
0.5 mass parts and appropriate purified water.
Preparation step is as follows:
A. above-mentioned raw materials are weighed according to parts by weight；
B. after the completion of step a, then smilax, dandelion, Korean ginseng, Asiatic plantain, honeysuckle and Radix Isatidis be put into
1-2h is impregnated in water, then the raw material after immersion is put into boiling vessel again and carries out boiling, and temperature when boiling is 90-
100 DEG C, the time of boiling is 1-2h；
C. after the completion of step b, then well-done medical fluid is put into filter and is filtered processing, mixed liquor is made
A；
D. after the completion of step c, weighed refined coptis extract, glycerol and butanediol are put into mixer, are added
Suitable purified water is mixed, and then mixed liquor A is added in mixer again and carries out mixed processing with raw material, and mixing is made
Object B；
E. after the completion of step d, then the mixture B being made staticly settled, with 4 layers filtered through gauze 3 times, then will filter
Liquid is placed on to decoct in small fire and be concentrated by evaporation, and the vaseline of its weight 1/10th is added in the medical fluid of paste, then use small fire
It decocts and is stirred continuously completion and receive cream, cream is dispensed into glass container, Whelk-eliminating paste completes.
Traditional Whelk-eliminating paste data parameters table 1 is as follows:
| Test item | Heat-clearing and damp-drying drug effect | Detoxicating functions | Antiviral efficacy | Anti-acne speed |
| Parameter index | Nothing | Nothing | Nothing | Slowly |
One Whelk-eliminating paste data parameters table 2 of embodiment is as follows:
| Test item | Heat-clearing and damp-drying drug effect | Detoxicating functions | Antiviral efficacy | Anti-acne speed |
| Parameter index | It is poor | It is poor | It is poor | Generally |
Two Whelk-eliminating paste data parameters table 3 of embodiment is as follows:
| Test item | Heat-clearing and damp-drying drug effect | Detoxicating functions | Antiviral efficacy | Anti-acne speed |
| Parameter index | It is good | It is good | It is good | Fastly |
It to sum up states, is obtained referring to the data comparison of table 1, table 2 and table 3, by the addition of refined coptis extract, can effectively be allowed
Whelk-eliminating paste has effects that heat-clearing and damp-drying drug and removing toxic substances, accelerates the speed that patient's small pox is dispelled, and the small pox for reducing patient occurs
The probability festered can effectively allow Whelk-eliminating paste to have antiviral and refrigerant effect, avoid small pox by the addition of honeysuckle
The phenomenon that infecting reduces the probability of small pox diffusion, improves the comfort in Whelk-eliminating paste use process.
The above shows and describes the basic principles and main features of the present invention and the advantages of the present invention, for this field skill
For art personnel, it is clear that invention is not limited to the details of the above exemplary embodiments, and without departing substantially from spirit of the invention or
In the case where essential characteristic, the present invention can be realized in other specific forms.Therefore, in all respects, should all incite somebody to action
Embodiment regards exemplary as, and is non-limiting, the scope of the present invention by appended claims rather than on state
Bright restriction, it is intended that including all changes that fall within the meaning and scope of the equivalent elements of the claims in the present invention
It is interior.Any reference signs in the claims should not be construed as limiting the involved claims.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiments being understood that.
Claims (8)
1. a kind of Whelk-eliminating paste containing refined coptis extract, it is characterised in that: including following raw material and its weight fraction: refined coptis extract
For 5-15 mass parts；Glycerol is 10-15 mass parts；Butanediol is 5-12 mass parts；Pearl powder is 3-8 mass parts；Smilax
For 2-5 mass parts；Dandelion is 3-4 mass parts；1-2 mass parts of Korean ginseng；Asiatic plantain is 3-6 mass parts；Honeysuckle is
2-7 mass parts；Radix Isatidis is 3-6 mass parts；Vaseline is 0.5-1 mass parts and appropriate purified water.
2. a kind of Whelk-eliminating paste containing refined coptis extract according to claim 1, it is characterised in that: including following raw material and its
Weight fraction: glycerol is 11 mass parts；Butanediol is 7 mass parts；Pearl powder is 5 mass parts；Smilax is 3 mass parts；Pu Gong
English is 4 mass parts；2 mass parts of Korean ginseng；Asiatic plantain is 4 mass parts；Honeysuckle is 6 mass parts；Radix Isatidis is 5g mass parts；It is all
Intellectual circle is 0.5 mass parts and appropriate purified water.
3. a kind of Whelk-eliminating paste containing refined coptis extract according to claim 1, it is characterised in that: including following raw material and its
Weight fraction: refined coptis extract is 8 mass parts；Glycerol is 11 mass parts；Butanediol is 7 mass parts；Pearl powder is 5 mass parts；
Smilax is 3 mass parts；Dandelion is 4 mass parts；2 mass parts of Korean ginseng；Asiatic plantain is 4 mass parts；Honeysuckle is 6 mass
Part；Radix Isatidis is 5g mass parts；Vaseline is 0.5 mass parts and appropriate purified water.
4. a kind of preparation method of Whelk-eliminating paste containing refined coptis extract according to claim 1, it is characterised in that: preparation step
It is rapid as follows:
A. above-mentioned raw materials are weighed according to parts by weight；
B. after the completion of step a, then smilax, dandelion, Korean ginseng, Asiatic plantain, honeysuckle and Radix Isatidis be put into water
1-2h to be impregnated, then the raw material after immersion is put into boiling vessel again and carries out boiling, temperature when boiling is 90-100 DEG C,
The time of boiling is 1-2h；
C. after the completion of step b, then well-done medical fluid is put into filter and is filtered processing, mixed liquor A is made；
D. after the completion of step c, weighed refined coptis extract, glycerol and butanediol are put into mixer, are added appropriate
Purified water mixed, then again by mixed liquor A be added in mixer and raw material carry out mixed processing, be made mixture B；
E. after the completion of step d, then the mixture B being made staticly settled, with 4 layers filtered through gauze 3 times, then filtrate is put
It decocts and is concentrated by evaporation in small fire, the vaseline of its weight 1/10th is added in the medical fluid of paste, then decocted with small fire
And be stirred continuously completion and receive cream, cream is dispensed into glass container, Whelk-eliminating paste completes.
5. a kind of preparation method of Whelk-eliminating paste containing refined coptis extract according to claim 4, it is characterised in that: the step
Material cooking Shi Xianyong high fire is decocted to boiling in rapid b changes small fire again, removal surfactant foam is stirred while decocting, after boiling 1 hour
Medical fluid is filtered to take out, the dregs of a decoction add water to decoct again, altogether repeatedly for three times.
6. a kind of preparation method of Whelk-eliminating paste containing refined coptis extract according to claim 4, it is characterised in that: the step
It is filtered when rapid c Chinese medicine liquid filtration treatment using ultrafiltration membrane, filtering carries out in three times, will will surpass after filtering each time
Filter membrane is replaced or is cleaned.
7. a kind of preparation method of Whelk-eliminating paste containing refined coptis extract according to claim 4, it is characterised in that: the step
Temperature when refined coptis extract, glycerol and butanediol mix in rapid d is 30-40 DEG C, and the mixed time is 10-20min, mixing
When revolving speed be 500-750r/min, mixed liquor A be added in mixer with raw material carry out mixed processing when, temperature be 45-
50 DEG C, the mixed time is 30-50min, and revolving speed when mixing is 800-1100r/min.
8. a kind of preparation method of Whelk-eliminating paste containing refined coptis extract according to claim 4, it is characterised in that: the step
It is decocted in rapid e and needs constantly agitation medical fluid when being concentrated by evaporation, take concentration while hot when the content in pot becomes semi-solid state
Medical fluid drop on dry mulberry paper, lose water mark around cream to drip as degree.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102886001A (en) * | 2012-10-31 | 2013-01-23 | 倪金福 | Acne removing traditional Chinese medicine and preparation method thereof |
| CN103860775A (en) * | 2014-03-12 | 2014-06-18 | 华明星 | Traditional Chinese medicine acne removing cream |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102886001A (en) * | 2012-10-31 | 2013-01-23 | 倪金福 | Acne removing traditional Chinese medicine and preparation method thereof |
| CN103860775A (en) * | 2014-03-12 | 2014-06-18 | 华明星 | Traditional Chinese medicine acne removing cream |
| CN106237035A (en) * | 2016-08-31 | 2016-12-21 | 洪雅县瓦屋山药业有限公司 | A kind of Chinese medicine formula utilizing refined even treatment acne |
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