CN109432065A - A kind of stealthy net acne patch of konjaku glucomannan - Google Patents
A kind of stealthy net acne patch of konjaku glucomannan Download PDFInfo
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- CN109432065A CN109432065A CN201811585931.7A CN201811585931A CN109432065A CN 109432065 A CN109432065 A CN 109432065A CN 201811585931 A CN201811585931 A CN 201811585931A CN 109432065 A CN109432065 A CN 109432065A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/045—Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
- A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline
- A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
- A61K31/355—Tocopherols, e.g. vitamin E
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/10—Anti-acne agents
Abstract
The present invention relates to stealthy net acne patches of a kind of konjaku glucomannan and preparation method thereof.The stealthy net acne patch of konjaku glucomannan has excellent film forming characteristics, gas permeability and adhesivity using konjaku glucomannan as primary raw material.It include: first layer, i.e., outermost layer is konjak portuguese gansu polyose gel layer, and the second layer is to contain the medicine layer based on salicylic acid, rosemary leaf oil, xanthan gum, tocopherol.Konjaku glucomannan belongs to wound dressing as a kind of hydrophilic hydrocolloid, has the ability for absorbing wound exudate, forms the closed surface of a wound, promote the formation of the hyperplasia and granulation tissue of capilary, to accelerate wound healing.The advantages of stealthy net acne patch of konjaku glucomannan of the invention has that gas permeability is high, at low cost, preparation process is simple, harmless to the human body, environment-friendly degradable, can become the novel effective product for resolving poxes that the majority of consumers select.
Description
The present invention relates to a kind of beautifying patchs for technical field, and in particular to a kind of stealthy net acne patch of konjaku glucomannan.
Background technique acne is commonly called as whelk, is a kind of infective inflammation of pilosebaceous follicle, puberty men and women morbidity
Rate highest, many adults are still perplexed by it.The generation of acne is mainly stifled with hypersteatosis, pilosebaceous duct
The factors such as plug, bacterium infection and inflammatory reaction are closely related.Mainly there is hoary hair and blackhead, papule, useless fellow, knot in face
Section and tumour, few patients even form recess or hyperplasia scar.Acne is not only a kind of skin disease, also drastically influences trouble
Social activity, psychology and the quality of life of person.
Currently, net acne patch on the market is used as a kind of medicinal cosmetic, refers generally to be pasted on suppurative acne surface, be formed
Protecting insulating layer reduces the chance contacted with external contamination, promotes the beauty product of the fast quick-recovery of acne, with hydrophilic gel system
At.Nowadays, there are many drug and the method for treating acne, but there is also many problems.Such as: external application Alphalin acids drug and
Benzoyl peroxide can make local skin flush, furfur occur, there is tight or burning sensation；Oral antibiotic can generate drug resistance；Mouthful
Taking hormone medicine will appear adverse reactions such as nauseous, drowsiness, weight gain etc..The milder anti-acne occurred in recent years produces
Product also have the shortcomings that low effort, at high cost, technique is cumbersome.
Application No. is 201410345637.4 patent of invention " aloe essential oil hydrogel acne-removing sheet and preparation method thereof " (Shens
Please day: 2014.07.19) describe it is a kind of with cassia seed, aloe, persimmon leaves, rheum officinale, Cortex Phellodendri, wild chrysanthemum, Gardenia, Fructus Forsythiae,
Aloe essential oil hydrogel acne-removing sheet and preparation method thereof based on the tens of kinds of extracted form natural plant ingredients such as the root bark of white mulberry, kuh-seng, tool
Have the advantages that ingredient and do not stimulate mildly, Bergamot Mint Extract, quality it is salubrious, but its preparation process is complicated, expensive raw material price.
Application No. is a kind of 201310544326.6 patent of invention " alga acne treatment paste " (applying date: 2013.10.31) Jie
Continued a kind of main component are as follows: seawood meal, banana skin water cooking liquid dry powder, snake slough, honeysuckle, Radix Astragali, Radix Ophiopogonis, polygonum cuspidate, remaining is
The alga acne treatment paste of cucumber extract adjusts fat secretion and promotion using pure plant components such as seawood meal, honeysuckle, Radix Astragalis
Cell metabolism soothes the skin red and swollen, anti-inflammatory and other effects to reach.This product has safe muting sensitive, easily absorbs, is free of chemical preservation
The advantages that agent, but it to the more demanding of material quality, at high cost, waterproofness and antibiotic property are poor, and this product can not be stealthy,
Be not suitable for the women out using of daily requirement makeup.
Application No. is 201520493293.1 patents " a kind of stealth disappear acne patch " (applying date: 2015.07.09) to describe
The stealth that anti-acne active matter is coated on a kind of hydrophilic hydrocolloid patch identical with human body complexion disappears acne patch, pastes thereon
Lining paper design it is humanized, the case where finger accidentally pollutes veneer when avoiding release backing paper.But this product is dispelled
Acne effect is poor, and gas permeability, waterproofness and antibiotic property are poor.
The object of the present invention is to provide a kind of stealthy net acnes of konjaku glucomannan different from existing acne-removing sheet for summary of the invention
Patch.
The present invention utilizes its excellent film forming characteristics, gas permeability and adhesivity system using konjaku glucomannan as primary raw material
Standby net acne is pasted, comprising: first layer, i.e. outermost layer are konjak portuguese gansu polyose gel layer, in conjunction with the second layer with containing rosemary leaf oil,
Medicine layer based on xanthan gum, tocopherol is attached to the fit central part, provides a kind of ventilative, antibacterial, nontoxic to the human body
Evil, net acne patch of environment-friendly degradable and preparation method thereof.
The preparation method of the stealthy net acne patch of konjaku glucomannan of the present invention, it is characterised in that preparation step is as follows:
(1) preparation of konjak portuguese gansu polyose gel layer
A, konjaku glucomannan purifying powder is prepared: by weight, in 3000~5000 parts, 65~70 DEG C of deionized water, side
It stirs side and 8~12 parts of konjaku powders is added, stand 2h after stirring 25~30min, remove insoluble impurities through filtering, retain filter
Liquid；Rotary evaporation filtrate concentrates it to the half of original volume, and the ethyl alcohol for being 80%~90% using volumetric concentration is poured into as precipitating reagent
It in filtrate after concentration, is stirred when pouring into, collects precipitating, washed with dehydrated alcohol and be placed on 30~35 DEG C of air dry oven
Then middle 4~6h of drying is placed in 20~30 DEG C of vacuum oven dryings and keeps constant to quality, it is pure to obtain konjaku glucomannan
Change powder；
B, 92~95 parts of purified waters the preparation of sol solutions: are added in 5~8 parts of konjaku glucomannan purifying powder, 2~4 parts of hydrogen peroxide
In, it is stirring evenly and then adding into 0.2~0.4 part of chitosan, at room temperature, stirs 1~2h with the blender that revolving speed is 500r/min,
Mixed sols is obtained, it is spare；
(2) preparation of anti-acne drug
A, it by 500 parts of water, 40 parts of xanthan gum, 500 parts of glycerol and 400 parts of menthols, is added in water phase pot, is heated to 80~85
DEG C, stirring is pumped into warmed-up emulsifying pot to after being completely dissolved, and is opened stirring, is cooled down after 5~10min of homogeneous；
B, continue to be cooled to 40~45 DEG C, 1~5 part of rosemary leaf oil is added and 0.1~0.5 part of tocopherol is stirred until homogeneous, makes
Obtain blemish clearing gel；
(3) coated and molded: konjaku glucomannan mixed sols liquid is coated in net acne mold type, by net acne mold type together with evil spirit
Taro Glucomannan mixed sols liquid is placed in thermostatic drying chamber, dry to konjak portuguese gansu polyose gel layer moisture content with 60~75 DEG C
It is 10%~15%, takes out, the konjak portuguese gansu polyose gel layer of first layer central concave is made in cooled to room temperature；By first
Layer konjak portuguese gansu polyose gel layer is taken off from net acne mold type, and blemish clearing gel is coated at central concave, places at room temperature
65h, solidification is to get the stealthy net acne patch of finished product konjaku glucomannan, last adhesion separate paper.
Wherein, step (1) is described prepares konjaku glucomannan purifying powder, and the konjaku powder of addition is 10 parts.
The preparation of step (1) described sol solutions: the konjaku glucomannan purifies 7 parts of powder, 3 parts of hydrogen peroxide, purified water 93
Part, 0.3 part of chitosan.
The preparation of step (2) the anti-acne drug, the rosemary leaf oil of addition are 3 parts.
The preparation of step (2) the anti-acne drug, the tocopherol of addition are 0.3 part.
The present invention goes back the stealthy net acne patch of konjaku glucomannan of Sustainable use above method preparation.
Advantages of the present invention and usefulness: the stealthy net acne patch of konjaku glucomannan of the invention, with konjaku glucomannan
Belong to wound dressing as a kind of hydrophilic hydrocolloid for primary raw material, there is the ability for absorbing wound exudate.It absorbs and seeps
After liquid, the hydrophilic particle in dressing can form the semi-solid material of similar gels, be attached to wound base portion, provide and maintained
Conducive to the wet environment of wound healing, acne secretion is absorbed, plays debridement function；Since konjaku glucomannan is with excellent
Film forming and viscosity can form the closed surface of a wound, promote the formation of the hyperplasia and granulation tissue of capilary, it is clear to be conducive to macrophage
Except necrotic tissue, to accelerate wound healing.
The stealthy net acne of konjaku glucomannan of the invention pastes sterilized processing, can reduce the hand contact surface of a wound, reduce bacterium
Infection chance；It is physical to prevent UVB from injuring, avoid pigmentation；Flexible, breathable is bonded skin, for daily requirement makeup
Women can also reduce color make-up superinfection caused by acne, and be easy to remove from wound surface；Material non-toxic has life
Object compatibility, and antibacterial activity can be provided for the surface of a wound.The stealthy net acne of konjaku glucomannan of the invention is pasted and is had on the market
The results are shown in Table 1 for net acne patch correlated performance test comparison.
The stealthy net acne patch of table 1, konjaku glucomannan of the invention pastes correlated performance test comparison with having net acne on the market
As a result
By test, the stealthy net acne of konjaku glucomannan of the invention pastes hemostatic, waterproofness, gas permeability, biocidal property and anti-acne
The properties such as effect are excellent.
Specific embodiment in order to sufficiently disclose stealthy net acne patch of konjaku glucomannan of the present invention and preparation method thereof, under
Invention is further described in detail in conjunction with the embodiments in face.
A kind of preparation method of the stealthy net acne patch of embodiment 1, konjaku glucomannan, comprising the following steps:
1. the preparation of konjak portuguese gansu polyose gel layer
(1) it prepares konjaku glucomannan purifying powder: by weight, in 3000 parts, 65 DEG C of deionized water, being added while stirring
8 parts of konjaku powders stand 2h after stirring 25min, remove insoluble impurities through filtering, retain filtrate；Rotary evaporation filtrate by its
It is concentrated into the half of original volume, the ethyl alcohol for being 80% using volumetric concentration is precipitating reagent, in the filtrate after pouring into concentration, when pouring into
Precipitating is collected in stirring, and dry 4h in the air dry oven for be placed on 30 DEG C is washed with dehydrated alcohol and is then placed in 20 DEG C of vacuum
Drying box drying is kept constant to quality, obtains konjaku glucomannan purifying powder；
(2) preparation of sol solutions: 5 parts of konjaku glucomannan purifying powder, 2 parts of hydrogen peroxide are added in 95 parts of purified waters, stirring is equal
0.2 part of chitosan is added after even, at room temperature, stirs 1h with the blender that revolving speed is 500r/min, obtains mixed sols, it is spare；
2. the preparation of anti-acne drug
(1) it by 500 parts of water, 40 parts of xanthan gum, 500 parts of glycerol and 400 parts of menthols, is added in water phase pot, is heated to 80 DEG C, stirs
It mixes to after being completely dissolved and is pumped into warmed-up emulsifying pot, open stirring, cool down after homogeneous 5min.
(2) continue to be cooled to 40 DEG C, 2 parts of rosemary leaf oils are added and 0.2 part of tocopherol is stirred until homogeneous, it is solidifying that anti-acne is made
Glue.
3. coated and molded: konjaku glucomannan mixed sols liquid being coated in net acne mold type, net acne mold type is connected
It is placed in thermostatic drying chamber with konjaku glucomannan mixed sols liquid, it is dry to konjak portuguese gansu polyose gel layer moisture content with 60 DEG C
It is 10%, takes out, the konjak portuguese gansu polyose gel layer of first layer central concave is made in cooled to room temperature；By first layer konjaku
Portuguese gansu polyose gel layer is taken off from net acne mold type, and blemish clearing gel is coated at fit central concave, places at room temperature
65h, solidification is to get the stealthy net acne patch of finished product konjaku glucomannan, finally, adhesion separate paper.
A kind of preparation method of the stealthy net acne patch of embodiment 2, konjaku glucomannan, comprising the following steps:
1. the preparation of konjak portuguese gansu polyose gel layer
(1) it prepares konjaku glucomannan purifying powder: by weight, in 4000 parts, 68 DEG C of deionized water, being added while stirring
10 parts of konjaku powders stand 2h after stirring 28min, remove insoluble impurities through filtering, retain filtrate；Rotary evaporation filtrate by its
It is concentrated into the half of original volume, the ethyl alcohol for being 85% using volumetric concentration is precipitating reagent, in the filtrate after pouring into concentration, when pouring into
Precipitating is collected in stirring, dry 5h in the air dry oven for be placed on 33 DEG C is washed with dehydrated alcohol, then be placed in 25 DEG C of vacuum drying
Case drying is kept constant to quality, obtains konjaku glucomannan purifying powder；
(2) preparation of sol solutions: 7 parts of konjaku glucomannan purifying powder, 3 parts of hydrogen peroxide are added in 93 parts of purified waters, stirring is equal
0.3 part of chitosan is added after even, at room temperature, stirs 1.5h with the blender that revolving speed is 500r/min, obtains mixed sols, it is standby
With；
2. the preparation of anti-acne drug
(1) 500 parts of water, 40 parts of xanthan gum, 500 parts of glycerol and 400 parts of menthols are added in water phase pot, are heated to 83 DEG C, stir
It mixes to after being completely dissolved and is pumped into warmed-up emulsifying pot, open stirring, cool down after homogeneous 8min.
(2) continue to be cooled to 43 DEG C, 3 parts of rosemary leaf oils be added and 0.3 part of tocopherol is stirred until homogeneous, sampling Detection,
It discharges after qualification and blemish clearing gel is made.
3. coated and molded: konjaku glucomannan mixed sols liquid being coated in net acne mold type, net acne mold type is connected
It is placed in thermostatic drying chamber with konjaku glucomannan mixed sols liquid, it is dry to konjak portuguese gansu polyose gel layer moisture content with 70 DEG C
It is 13%, takes out, the konjak portuguese gansu polyose gel layer of first layer central concave is made in cooled to room temperature.By first layer konjaku
Portuguese gansu polyose gel layer is taken off from net acne mold type, and blemish clearing gel is coated at fit central concave, places at room temperature
65h, solidification is to get the stealthy net acne patch of finished product konjaku glucomannan, last adhesion separate paper.
A kind of preparation method of the stealthy net acne patch of embodiment 3, konjaku glucomannan, comprising the following steps:
1. the preparation of konjak portuguese gansu polyose gel layer
(1) it prepares konjaku glucomannan purifying powder: by weight, in 5000 parts, 70 DEG C of deionized water, being added while stirring
12 parts of konjaku powders stand 2h after stirring 30min, remove insoluble impurities through filtering, retain filtrate；Rotary evaporation filtrate by its
It is concentrated into the half of original volume, the ethyl alcohol for being 90% using volumetric concentration is precipitating reagent, in the filtrate after pouring into concentration, when pouring into
Precipitating is collected in stirring, dry 6h in the air dry oven for be placed on 35 DEG C is washed with dehydrated alcohol, then be placed in 30 DEG C of vacuum drying
Case drying is kept constant to quality, obtains konjaku glucomannan purifying powder；
(2) preparation of sol solutions: 8 parts of konjaku glucomannan purifying powder, 4 parts of hydrogen peroxide are added in 92 parts of purified waters, stirring is equal
0.4 part of chitosan is added after even, at room temperature, stirs 2h with the blender that revolving speed is 500r/min, obtains mixed sols, it is spare；
2. the preparation of anti-acne drug
(1) it by 500 parts of water, 40 parts of xanthan gum, 500 parts of glycerol and 400 parts of menthols, is added in water phase pot, is heated to 85 DEG C, stirs
It mixes to after being completely dissolved and is pumped into warmed-up emulsifying pot, open stirring, cool down after homogeneous 10min.
(2) continue to be cooled to 45 DEG C, 4 parts of rosemary leaf oils be added and 0.4 part of tocopherol is stirred until homogeneous, sampling Detection,
It discharges after qualification and blemish clearing gel is made.
3. coated and molded: konjaku glucomannan mixed sols liquid being coated in net acne mold type, net acne mold type is connected
It is placed in thermostatic drying chamber with konjaku glucomannan mixed sols liquid, it is dry to konjak portuguese gansu polyose gel layer moisture content with 75 DEG C
It is 15%, takes out, the konjak portuguese gansu polyose gel layer of first layer central concave is made in cooled to room temperature.By first layer konjaku
Portuguese gansu polyose gel layer is taken off from net acne mold type, and blemish clearing gel is coated at fit central concave, places at room temperature
65h, solidification is to get the stealthy net acne patch of finished product konjaku glucomannan, last adhesion separate paper.
The foregoing is merely presently preferred embodiments of the present invention, all equivalent changes done according to scope of the present invention patent with
Modification, is all covered by the present invention.
Claims (6)
1. a kind of preparation method of the stealthy net acne patch of konjaku glucomannan, it is characterised in that preparation step is as follows:
(1) preparation of konjak portuguese gansu polyose gel layer
A, konjaku glucomannan purifying powder is prepared: by weight, in 3000~5000 parts, 65~70 DEG C of deionized water, side
It stirs side and 8~12 parts of konjaku powders is added, stand 2h after stirring 25~30min, remove insoluble impurities through filtering, retain filter
Liquid；Rotary evaporation filtrate concentrates it to the half of original volume, and the ethyl alcohol for being 80%~90% using volumetric concentration is poured into as precipitating reagent
It in filtrate after concentration, is stirred when pouring into, collects precipitating, washed with dehydrated alcohol and be placed on 30~35 DEG C of air dry oven
Then middle 4~6h of drying is placed in 20~30 DEG C of vacuum oven dryings and keeps constant to quality, it is pure to obtain konjaku glucomannan
Change powder；
B, 92~95 parts of purified waters the preparation of sol solutions: are added in 5~8 parts of konjaku glucomannan purifying powder, 2~4 parts of hydrogen peroxide
In, it is stirring evenly and then adding into 0.2~0.4 part of chitosan, at room temperature, stirs 1~2h with the blender that revolving speed is 500r/min,
Mixed sols is obtained, it is spare；
(2) preparation of anti-acne drug
A, it by 500 parts of water, 40 parts of xanthan gum, 500 parts of glycerol and 400 parts of menthols, is added in water phase pot, is heated to 80~85
DEG C, stirring is pumped into warmed-up emulsifying pot to after being completely dissolved, and is opened stirring, is cooled down after 5~10min of homogeneous；
B, continue to be cooled to 40~45 DEG C, 1~5 part of rosemary leaf oil is added and 0.1~0.5 part of tocopherol is stirred until homogeneous, makes
Obtain blemish clearing gel；
(3) coated and molded: konjaku glucomannan mixed sols liquid is coated in net acne mold type, by net acne mold type together with evil spirit
Taro Glucomannan mixed sols liquid is placed in thermostatic drying chamber, dry to konjak portuguese gansu polyose gel layer moisture content with 60~75 DEG C
It is 10%~15%, takes out, the konjak portuguese gansu polyose gel layer of first layer central concave is made in cooled to room temperature；By first
Layer konjak portuguese gansu polyose gel layer is taken off from net acne mold type, and blemish clearing gel is coated at central concave, places at room temperature
65h, solidification is to get the stealthy net acne patch of finished product konjaku glucomannan, last adhesion separate paper.
2. a kind of preparation method of the stealthy net acne patch of konjaku glucomannan, it is characterised in that step (1) is described to prepare Amorphophallus rivieri glucomannan
Glycan purification powder, the konjaku powder of addition are 10 parts.
3. a kind of preparation method of the stealthy net acne patch of konjaku glucomannan, it is characterised in that the preparation of step (1) described sol solutions:
The konjaku glucomannan purifies 7 parts of powder, 3 parts of hydrogen peroxide, 93 parts of purified water, 0.3 part of chitosan.
4. a kind of preparation method of the stealthy net acne patch of konjaku glucomannan, it is characterised in that the system of step (2) the anti-acne drug
Standby, the rosemary leaf oil of addition is 3 parts.
5. a kind of preparation method of the stealthy net acne patch of konjaku glucomannan, it is characterised in that the system of step (2) the anti-acne drug
Standby, the tocopherol of addition is 0.3 part.
6. the stealthy net acne patch of the konjaku glucomannan that either as described in claim 1-5 prepared by method.
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN111568850A (en) * | 2020-05-14 | 2020-08-25 | 上海应用技术大学 | Acne microecological imbalance improving preparation containing konjac polysaccharide and application thereof |
| CN112706477A (en) * | 2020-12-28 | 2021-04-27 | 河南亚都实业有限公司 | Dandelion wool-based antibacterial hemostatic dressing |
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Application publication date: 20190308 |