CN109419849A - It is a kind of for treating the Chinese medicine of Liver Cirrhotic Jaundice - Google Patents

Abstract

The present invention relates to a kind of for treating the Chinese medicine of Liver Cirrhotic Jaundice, it is prepared by the raw medicinal material of following weight proportion: 15 parts of Radix Salviae Miltiorrhizae, 5 parts of safflower, 5 parts of radix scutellariae, 10 parts of oriental wormwood, 15 parts of Radix Isatidis, 9 parts of ganoderma lucidum, 5 parts of kuh-seng.Clinical experiments have proved that the present invention can safely and effectively treat Liver Cirrhotic Jaundice.

Description

It is a kind of for treating the Chinese medicine of Liver Cirrhotic Jaundice

Technical field

The present invention relates to a kind of Chinese medicines, and in particular to a kind of for treating the Chinese medicine of Liver Cirrhotic Jaundice.

Background technique

Cirrhosis is with a kind of common chronic disease, is to cause liver by one or more causes of disease are long-term or repeated action Cell diffusivity solid lesion.Lead to lobuli hepatis including degeneration of liver cells, necrosis, regeneration, liver tubercle and proliferation of fibrous tissue Structure reconstruction, it is that liver is gradually denaturalized, is hardened and forms cirrhosis that pseudolobuli and tubercle, which are formed,.The reason of causing cirrhosis has: Virus hepatitis, snail fever, alcoholism, chemical toxicant or drug, cholestasis, dyshaemia, malnutrition and reason It is unknown etc..Cirrhosis clinical manifestation are as follows: liver function is compensatory and Decompensated stage.Compensatory phase no obvious symptom, or show as it is out of strength, Loss of appetite, the symptom for detesting the chronic liver diseases such as oil, abdominal distension, nausea.The compensatory phase is then based on liver dysfunction and portal hypertension It shows.Tendency can be begun to learn, low fever, jaundice, pruitus, anaemia, ascites, liver palms, spleen enlargement are hardened.Decompensated stage removes Obvious abnormal outer, the prolonged prothrombin of above-mentioned liver function, Archon albumen are inverted.Common complication have upper gastrointestinal bleeding, Hepatorenal syndrome, hepatic encephalopathy, secondary infection and primary carcinoma of liver.

Medicinal material present Research involved in the present invention is as follows:

Radix Salviae Miltiorrhizae [alias] red root, clovershrub, blood join root, blood mountain root, RADIX SALVIAE MILTIORRHIZAE, radix salviae miltiorrhizae.[source] this product is Labiatae plant The drying root and rhizome of object Radix Salviae Miltiorrhizae.Spring, the excavation of two season of autumn, silt is removed, it is dry.[nature and flavor] are bitter, slightly cold.[channel tropism] return heart, liver Through.[major function] stasis-dispelling and pain-killing, blood circulation, relieving restlessness and restlessness.For irregular menstruation, amenorrhea and algomenorrhea, a lump in the abdomen causing distension and pain, chest and abdomen thorn Bitterly, hot numbness pain, sore and ulcer, swelling and pain, upset and sleepless；Hepatosplenomegaly, angina pectoris.[usage and dosage] is for oral administration: decoction, 9~15g.[note Meaning] it should not be with black false hellebore with use.[extracts] " China's book on Chinese herbal medicine "

Safflower [alias] safflower.[source] this product is the dry flower of compositae plant safflower.Summer flower from yellow to red when picking take Tubular flower pays attention to the ovary for not hurting base portion, removes impurity, dries in the shade or small fire is dried, and matter is softer at this time, and color depth is red best.(harvesting When flower, should carry out when morning dew is dry as early as possible, the sharp thorn of bract is softer, but also it is unsuitable too early.).[nature and flavor] are acrid in flavour and warm in nature.[channel tropism] Converge to heart and liver channels.[major function] blood circulation, removing blood stasis and acesodyne.For menostasis, dysmenorrhea, lochia, abdominal mass lump in the abdomen falls and flutters damage Wound, sore swell and ache curative.[usage and dosage] is for oral administration: decoction, 3~9g.[attention] pregnant woman is used with caution.[extracts] " China's book on Chinese herbal medicine ".

Radix scutellariae [alias] Radix Scutellariae, scutellaria tea, tsuchikane tea root.[source] this product is the drying of Lamiaceae plant radix scutellariae Root.Spring, the excavation of two season of autumn, fibrous root and silt are removed, rough bark is hit after solarization, dries.[nature and flavor] are bitter, tremble with fear.[channel tropism] return lung, gallbladder, Spleen, large intestine, small intestinl channel.[major function] heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention.It is wet for damp-warm syndrome, heat temperature chest tightness and emesis Hot feeling of fullness, dysentery, jaundice, cough with lung heat, hyperpyrexia polydipsia, blood-head tells nosebleed, carbuncle sore tumefacting virus, threatened abortion.[usage and dosage] is for oral administration: Decoction, 3-9g.[attention] Fructus Corni, keel make for it.It is real to dislike green onion.Fear cinnabar, tree peony, black false hellebore.[extracts] " China's book on Chinese herbal medicine ".

Oriental wormwood [alias] capillary wormwood, Artemisia capillaris, Artemisia stelleriana, suede wormwood artemisia, monkey hair.[source] product are compositae plant artemisia scoparia or oriental wormwood The dry aerial parts of wormwood artemisia.It is tapped when harvesting or autumn bud grow up to when spring seedling high 6~10cm, removes impurity and old stem, It dries.The spring habit of harvesting claims " capillary wormwood ", the title " Artemisia capillaris " that autumn taps.[nature and flavor] are bitter, pungent, slightly cold.[channel tropism] returns Spleen, stomach, liver, gallbladder channel.[major function] clearing away damp-heat, removing jaundice subcutaneous ulcer.For jaundice oliguria, itchy sore；Infectious jaundice type hepatitis. [usage and dosage] is for oral administration: decoction, 6~15g.[extracts] " China's book on Chinese herbal medicine ".

Radix Isatidis [alias] great Lan root, manyflower glorybower root.[source] this product is the dry root of cruciferae isatis.Autumn adopts It digs, removes silt, dry.[nature and flavor] are bitter, tremble with fear.[channel tropism] return heart, stomach meridian.[major function] is clearing heat and detoxicating, cool blood relieving sore-throat.With In febrile virulent maculae, tongue is dark reddish purple dark, mumps, sore throat, scarlet fever, major part pestilence, erysipelas, carbuncle swells.[usage and dosage] is for oral administration: decocting Soup, 9-15g.[attention] is physically weak and avoids clothes without excess fire heat toxin person.[extracts] " China's book on Chinese herbal medicine ".

Ganoderma lucidum [alias] polyporus lucidus, Ganoderma, Ganoderma Lucidum.[source] this product is On Polyporaceae red sesame or purple sesame Dry fructification.Whole year harvesting, removes impurity, wipes out the lower end stem with rotten wood, silt or culture substrate, dry in the shade or 40 ~50 DEG C of drying.[nature and flavor] sweet and neutral.[channel tropism] return heart, lung, liver and kidney channel.[major function] invigorating qi for tranquilization, it is relieving cough and asthma.With In dizziness egersis, shortness of breath and palpitation, consumptive disease cough and asthma.[usage and dosage] is for oral administration: decoction, 6~12g.[extracts] " China's book on Chinese herbal medicine ".

Kuh-seng [alias] open country Chinese scholartree, Hao Hanzhi, matrine, bone, Chinese scholartree, Albizzia kalkora.[source] this product is that leguminous plant is bitter The dry root of ginseng.Spring, the excavation of two season of autumn, root head and small supporting root, cleaning, drying are removed, or take advantage of fresh slices, it is dry.[nature and flavor] are bitter, It is cold.[channel tropism] return heart, liver, stomach, large intestine, bladder meridian.[major function] heat-clearing and damp-drying drug, desinsection, diuresis.For hot dysentery, hematochezia is yellow Subcutaneous ulcer renal shutdown, leukorrhea with reddish discharge, swelling of vulva pruritus vulvae, eczema, wet sore, pruitus, castor；Trichomonas vaginitis is controlled outside.[usage is used Amount] for oral administration: decoction, 4.5~9g.[attention] should not be with black false hellebore with use.[extracts] " China's book on Chinese herbal medicine ".

Summary of the invention

The present invention is intended to provide it is a kind of for treating the Chinese medicine of Liver Cirrhotic Jaundice, by selecting suitable medicinal material and its matching Than achieving the purpose that safely and effectively to cure Liver Cirrhotic Jaundice.

In order to achieve the above object, the invention adopts the following technical scheme:

It is a kind of for treating the Chinese medicine of Liver Cirrhotic Jaundice, which is characterized in that it be by following weight proportion raw medicinal material prepare It forms: 15 parts of Radix Salviae Miltiorrhizae, 5 parts of safflower, 5 parts of radix scutellariae, 10 parts of oriental wormwood, 15 parts of Radix Isatidis, 9 parts of ganoderma lucidum, 5 parts of kuh-seng.

The beneficial effects of the present invention will now be described with reference to clinical experimental data:

1, general information

Outpatient service and in hospital Liver Cirrhotic Jaundice patient 64 are collected between October in inventor in October, 2012 ~ 2013 year altogether, are randomly divided into Treatment group 32 and control group 32, treatment group male 24, female 8, the age 30~68 years old, average age 45 years old；Control group male 18, female 14, the age 30~68 years old, average age 45 years old.2 groups of genders, age and course of disease comparing difference are not statistically significant, It is comparable.

Diagnostic criteria

Diagnostic criteria according to national Liver Cirrhotic Jaundice dye clinical speciality meeting: (1), often have that out of strength, skin and mucosa is pale, spleen is swollen Greatly, the visible red blood cell of blood test and hemoglobin reduce, and granulophilocyte obviously increases, bone marrow examination erythron hyperplasia, Liver biochemical analysis unconjugated bilirubin is light, moderate increases, normal in conjunction with bilirubin；(2), there are anorexia, out of strength, hepatic region or upper abdomen Discomfort, urinates color depth, hepatomegaly, and chronic liver disease has splenomegaly or ascites；(3), there are the performances such as itch, stool color be shallow.

2, test method

2.1 treatment method

The oral present invention for the treatment of group is according to capsule made from specific embodiment 3,2 times a day.The course for the treatment of 1 month.

Control group takes orally Yin Zhi Huang piece, and 5 tablets once, takes orally 2 times a day, the course for the treatment of 1 month.

3, criterion of therapeutical effect and treatment results

3.1 criterion of therapeutical effect

Clinic control: Clinical symptom and sign disappears, and serum T BIL restores normal；

Effective: Clinical symptom and sign disappears substantially, and serum T BIL restores normal；

Effective: clinical symptom relief, serum T BIL reduce by more than 50；

Invalid: the state of an illness is without improving or be further aggravated.

3.2 treatment results are shown in Table 1.

1 two groups of curative effects of table compare

Group	n	Clinic control	It is effective	Effectively	In vain	Total effective rate (%)	Serious adverse reaction example
								Treatment group	32	7	15	6	4	87.5%	0
Control group	32	2	9	7	14	56.2%	0

As it can be seen that drug produced by the present invention can safely and effectively treat Liver Cirrhotic Jaundice, there is promotional value.

Specific embodiment

In order to better understand and implement the present invention, the present invention is further illustrated combined with specific embodiments below.

Embodiment 1

It weighs: 15 grams of Radix Salviae Miltiorrhizae, 5 grams of safflower, 5 grams of radix scutellariae, 10 grams of oriental wormwood, 15 grams of Radix Isatidis, 9 grams of ganoderma lucidum, 5 grams of kuh-seng；Add 8 times of amounts Water decocts 1.5 hours, filtering；Filter residue adds 6 times of amount water, decocts 1 hour, filtering；Merging filtrate is concentrated into 120 grams to get symbol Close the decoction of one day dosage of normal adult.

For treating Liver Cirrhotic Jaundice.Oral, every bu is taken twice sooner or later.

Embodiment 2

It weighs: 15 grams of Radix Salviae Miltiorrhizae, 5 grams of safflower, 5 grams of radix scutellariae, 10 grams of oriental wormwood, 15 grams of Radix Isatidis, 9 grams of ganoderma lucidum, 5 grams of kuh-seng；Add 10 times Water is measured, is decocted 2 hours, filtering；Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate is concentrated, dry, packaging, i.e., The powder of one day dosage of normal adult must be met.

For treating Liver Cirrhotic Jaundice.Oral, every bu is taken twice sooner or later.

Embodiment 3

It weighs: 15 grams of Radix Salviae Miltiorrhizae, 5 grams of safflower, 5 grams of radix scutellariae, 10 grams of oriental wormwood, 15 grams of Radix Isatidis, 9 grams of ganoderma lucidum, 5 grams of kuh-seng；Add 6 times of amounts Water decocts 3 times, decocts 1 hour every time, merges decoction liquor, is concentrated, dry, is packed into capsule shells to get normal adult is met one day The capsule of dosage.

For treating Liver Cirrhotic Jaundice.Oral, every bu is taken twice sooner or later.

Claims (4)

1. a kind of for treating the Chinese medicine of Liver Cirrhotic Jaundice, which is characterized in that it is by the raw medicinal material system of following weight proportion It is standby to form: 15 parts of Radix Salviae Miltiorrhizae, 5 parts of safflower, 5 parts of radix scutellariae, 10 parts of oriental wormwood, 15 parts of Radix Isatidis, 9 parts of ganoderma lucidum, 5 parts of kuh-seng.

2. being used for the Chinese medicine of Liver Cirrhotic Jaundice as described in claim 1, which is characterized in that preparation method are as follows: weigh: Radix Salviae Miltiorrhizae 15 parts, 5 parts of safflower, 5 parts of radix scutellariae, 10 parts of oriental wormwood, 15 parts of Radix Isatidis, 9 parts of ganoderma lucidum, 5 parts of kuh-seng；Add 8 times of amount water, it is small to decoct 1.5 When, filtering；Filter residue adds 6 times of amount water, decocts 1 hour, filtering；Merging filtrate is concentrated into 120 parts to get decoction；Above-mentioned part is Refer to parts by weight.

3. as described in claim 1 for treating the Chinese medicine of Liver Cirrhotic Jaundice, which is characterized in that preparation method are as follows: weigh: 15 parts of Radix Salviae Miltiorrhizae, 5 parts of safflower, 5 parts of radix scutellariae, 10 parts of oriental wormwood, 15 parts of Radix Isatidis, 9 parts of ganoderma lucidum, 5 parts of kuh-seng；Add 10 times of amount water, decocts 2 Hour, filtering；Filter residue adds 8 times of amount water, decocts 1.5 hours, filtering；Merging filtrate is concentrated, dry, packs to get powder；On It states part and each means parts by weight.

4. as described in claim 1 for treating the Chinese medicine of Liver Cirrhotic Jaundice, which is characterized in that preparation method are as follows: weigh: 15 parts of Radix Salviae Miltiorrhizae, 5 parts of safflower, 5 parts of radix scutellariae, 10 parts of oriental wormwood, 15 parts of Radix Isatidis, 9 parts of ganoderma lucidum, 5 parts of kuh-seng；Add 6 times of amount water, decocts 3 It is secondary, it decocts 1 hour every time, merges decoction liquor, be concentrated, it is dry, capsule shells are packed into get capsule；Above-mentioned part each means weight Part.