CN109364135A - A kind of fruit of Cherokee rose standard decoction freeze-dried powder and its production technology - Google Patents
A kind of fruit of Cherokee rose standard decoction freeze-dried powder and its production technology Download PDFInfo
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Abstract
The present invention relates to fruit of Cherokee rose deep processing field, a kind of fruit of Cherokee rose standard decoction freeze-dried powder and its production technology are provided, the fruit of Cherokee rose freeze-drying prods viscosity for solving the problems, such as conventional lyophilized technique preparation is big, it is serious to collapse.A kind of fruit of Cherokee rose standard decoction freeze-dried powder provided by the invention takes the fruit of Cherokee rose 1 ~ 5mL of standard decoction, and 1 ~ 30% freeze drying protectant is added, freeze-dried powder can be obtained after freeze-drying.Addition freeze drying protectant can make obtained freeze-dried powder surfacing, uniform color, hygroscopicity small, effectively raise the quality of product.
Description
Technical field
The present invention relates to fruit of Cherokee rose deep processing fields, and in particular to a kind of fruit of Cherokee rose standard decoction freeze-dried powder and its production
Technique.
Background technique
The fruit of Cherokee rose (Rosa laevigata Michx) is the dry mature fruit of the rosaceous plant fruit of Cherokee rose, has heat-clearing
The effect of removing toxic substances, is mainly used for emission and spermatorrhea, enuresis frequent micturition, metrorrhagia and metrostaxis leukorrhagia.Fruit of Cherokee rose plant is distributed widely in China Central China, China
The height above sea level such as south, the southeast and southwest are in the hillside fields shrubbery on the sunny side of 50-1600m.The fruit of Cherokee rose is fruit class tonic, according to " Chinese medicine
The control of granule quality and standard formulation technical requirements " in " standard decoction preparation " is related requires, referring to the Ministry of Public Health, it is national in
Drug Administration's " medical institutions' Traditional Chinese medicine decocting room management regulation " determine its decoct number, amount of water, the indexs such as decocting time and
Parameter simultaneously carries out related process investigation preparation fruit of Cherokee rose standard decoction.Vacuum Freezing & Drying Technology is mainly by solution in low temperature item
Crystallization directly distillation removes the moisture in sample under part, therefore freeze-drying can sufficiently keep the object of the samples such as fruit of Cherokee rose standard decoction
Reason, chemical stability and bioactivity.
Currently, the freeze-drying process that most of Chinese medicine prepares standard decoction can be not added protective agent, but for containing carbohydrate content compared with
The freeze-dried powder of big kind often occurs that viscosity is excessive, collapses serious situation, is unable to reach ideal effect.
Summary of the invention
Present invention solves the technical problem that being that fruit of Cherokee rose freeze-drying prods viscosity prepared by conventional lyophilized technique is big, it is serious to collapse
The problem of, a kind of fruit of Cherokee rose standard decoction freeze-dried powder is provided.
In order to solve the above technical problem, the present invention provides technical solution are as follows:
A kind of fruit of Cherokee rose standard decoction freeze-dried powder takes the fruit of Cherokee rose 1 ~ 5mL of standard decoction, and 1 ~ 30% freeze drying protectant, freezing is added
Freeze-dried powder can be obtained after drying.
Freeze drying protectant is mixed in a certain amount of fruit of Cherokee rose standard decoction, can effectively be prevented in freezing dry process
Freeze-drying prods occur that viscosity is excessive, collapses serious situation.
Addition freeze drying protectant can make obtained freeze-dried powder surfacing, uniform color, hygroscopicity small, effective to improve
The quality of product.
Preferably, the freeze drying protectant be sucrose, maltodextrin, lactose, beta-cyclodextrin, salt, starch wherein
It is one or more of.The protective agents such as maltodextrin, lactose, beta-cyclodextrin, which can effectively prevent freeze-dried powder, to be there is severe atrophy, glues
Spend big situation.
Preferably, the freeze drying protectant is maltodextrin, and the dosage of the maltodextrin is 10%.Add 10%
Maltodextrin as freeze drying protectant, can effectively prevent freeze-drying prods and occur that viscosity is excessive, collapses serious situation；Together
When the freeze-drying rates of freeze-drying prods can be improved, reduce hygroscopicity.
Preferably, the density of the fruit of Cherokee rose standard decoction is 1g/mL.The fruit of Cherokee rose standard decoction incorporation 10% of 1g/mL
Maltodextrin freeze-drying after freeze-dried powder obtained quality it is best.
Preferably, the solidification point of the freeze-drying is -55 ~ -45 DEG C, and the freeze-off time is no less than 2 ~ 4h；
It is warming up to -40 ~ -32 DEG C after freezing, in 5 ~ 10min, after maintaining 15 ~ 25h, is warming up to -33 ~ -28 DEG C, maintain 15 ~
20min；It is warming up to -25 ~ -15 DEG C again, maintains 5 ~ 15h, is continuously heating to -15 ~ -5 DEG C, maintains 3 ~ 10h；Heating in 5 ~ 10min
To 20 ~ 35 DEG C, parsing-desiccation is carried out.Two sublimation temperatures are set in freeze-drying process, respectively -40 ~ -32 DEG C, maintain 15 ~ 25h
Afterwards；- 33 ~ -28 DEG C are warming up to, 15 ~ 20h is maintained, can effectively prevent freeze-dried powder spray bottle and collapse.
Preferably, the solidification point of the freeze-drying is -50 ~ -45 DEG C, and the freeze-off time is no less than 3 ~ 4h；
It is warming up to -35 ~ -32 DEG C after freezing, in 8 ~ 10min, after maintaining 20 ~ 25h, is warming up to -30 ~ -28 DEG C, maintains 18 ~ 20h；
It is warming up to -20 ~ -15 DEG C again, maintains 10 ~ 15h, is continuously heating to -10 ~ -5 DEG C, maintains 5 ~ 10h；It is warming up to 30 in 8 ~ 10min ~
35 DEG C, carry out parsing-desiccation.
Preferably, the solidification point of the freeze-drying is -50 DEG C, and the freeze-off time is no less than 3h；Freeze to tie
It is warming up to -35 DEG C in Shu Hou, 8min, after maintaining 20h, is warming up to -30 DEG C, maintains 18h；It is warming up to -20 DEG C again, maintains 10h, after
It is continuous to be warming up to -10 DEG C, maintain 5h；It is warming up to 30 DEG C in 8min, carries out parsing-desiccation.- 35 DEG C and -30 are set by sublimation temperature
DEG C, high production efficiency, good product quality.
A kind of fruit of Cherokee rose standard decoction freeze-dried powder, the freeze-dried powder prepared according to above-mentioned technique.
Preferably, the moisture content of the freeze-dried powder is 2 ~ 4%, and catechin content is 0.005 ~ 0.15%.Catechin has
A variety of effects, the freeze-dried products such as antitumor, anti-oxidant, Anti-bacterium and protection heart and brain organ can protect golden cherry to greatest extent
Catechin in substandard decoction.
Preferably, the moisture content of the freeze-dried powder is 2.58%, catechin content 0.088%.It is dry according to above-mentioned freezing
In freeze-dried powder made from drying process, catechin 0.088%, effect is best when moisture content is 2.58%, yield highest.
Fruit of Cherokee rose standard decoction in the application the preparation method comprises the following steps: take 10 ~ 20 mass parts of the fruit of Cherokee rose, 90 ~ 180 matter are added
The purified water for measuring part, decocts after the fruit of Cherokee rose is impregnated 30 ~ 60min in purified water；After boiling by intense fire, filled every 20min
Divide stirring primary, use mild fire instead and decoct 40 ~ 60min slowly, be separated by solid-liquid separation while hot, decoction is taken to obtain decoction medicament for the first time；Obtain the
It is decocted again after primary decoction medicament, adds the deionized water of 70 ~ 140 mass parts, after boiling by intense fire, filled every 20min
Divide stirring primary, uses mild fire instead and decoct 30 ~ 40min slowly, be separated by solid-liquid separation while hot, decoction is taken to obtain second of decoction decoction；By first
After secondary decoction decoction and second of decoction decoction are cooling, it is mixed to get mixed liquor；Mixed liquor is depressurized at 50 c
Concentration, until obtaining the liquid extract of 1:1, obtains standard decoction.
Compared with prior art, the device have the advantages that are as follows: addition freeze drying protectant can make freeze-drying obtained
Powder surfacing, uniform color, hygroscopicity are small, effectively raise the quality of product；10% maltodextrin is added to protect as freeze-drying
Agent is protected, freeze-drying prods is can effectively prevent and occurs that viscosity is excessive, collapses serious situation；Freeze-drying prods can be improved simultaneously
Freeze-drying rate and hygroscopicity.
Specific embodiment
Following implementation column is to further explanation of the invention, is not limitation of the present invention.
Embodiment 1
A kind of fruit of Cherokee rose standard decoction freeze-dried powder takes fruit of Cherokee rose standard decoction 2mL, and 10% freeze drying protectant is added, freeze-drying
After freeze-dried powder can be obtained.The freeze drying protectant is maltodextrin.The density of the fruit of Cherokee rose standard decoction is 1g/
mL.The solidification point of the freeze-drying is -50 DEG C, and the freeze-off time is no less than 3h；After freezing, risen in 8min
Temperature is to -35 DEG C, after maintaining 20h, is warming up to -30 DEG C, maintains 18h；It is warming up to -20 DEG C again, maintains 10h, is continuously heating to -10
DEG C, maintain 5h；It is warming up to 30 DEG C in 8min, carries out parsing-desiccation.
Freeze drying protectant is mixed in a certain amount of fruit of Cherokee rose standard decoction, can effectively be prevented in freezing dry process
Freeze-drying prods occur that viscosity is excessive, collapses serious situation.
Addition freeze drying protectant can make obtained freeze-dried powder surfacing, uniform color, hygroscopicity small, effective to improve
The quality of product.10% maltodextrin is added as freeze drying protectant, freeze-drying prods is can effectively prevent and viscosity mistake occurs
Greatly, serious situation is collapsed；The freeze-drying rate of freeze-drying prods can be improved simultaneously, and reduce hygroscopicity.Gold made from different modes
Density, eutectic point or the eutectic point of cherry substandard decoction have certain difference, but are added 10% in fruit of Cherokee rose standard decoction
Maltodextrin can effectively improve the quality of freeze-drying prods.The maltodextrin of the fruit of Cherokee rose standard decoction incorporation 10% of 1g/mL
The quality of freeze-dried powder obtained is best after freeze-drying.- 35 DEG C and -30 DEG C are set by sublimation temperature, high production efficiency, product
It is high-quality.
Embodiment 2
Embodiment 2 with embodiment 1 the difference is that, take fruit of Cherokee rose standard decoction 2mL, 1% freeze drying protectant be added, freeze
Freeze-dried powder can be obtained after drying.The freeze drying protectant is maltodextrin.The solidification point of the freeze-drying is -55
DEG C, the freeze-off time is no less than 2h；After freezing, it is warming up to -40 DEG C in 5min, after maintaining 15h, is warming up to -33 DEG C,
Maintain 15h；It is warming up to -25 DEG C again, maintains 5h, is continuously heating to -15 DEG C, maintains 3h；It is warming up to 20 DEG C in 5min, is parsed
It is dry.
- 40 DEG C and -30 DEG C are set by sublimation temperature, high production efficiency, good product quality.Catechin have it is antitumor,
A variety of effects, the freeze-dried products such as anti-oxidant, Anti-bacterium and protection heart and brain organ can protect fruit of Cherokee rose standard to greatest extent
Catechin in decoction.
Embodiment 3
Embodiment 3 with embodiment 1 the difference is that, take fruit of Cherokee rose standard decoction 2mL, 30% freeze drying protectant be added, freeze
Freeze-dried powder can be obtained after drying.The freeze drying protectant is maltodextrin.The solidification point of the freeze-drying is -45
DEG C, the freeze-off time is no less than 4h；After freezing, it is warming up to -32 DEG C in 10min, after maintaining 25h, is warming up to -28
DEG C, maintain 20h；It is warming up to -15 DEG C again, maintains 15h, is continuously heating to -5 DEG C, maintains 10h；35 DEG C are warming up in 10min, into
Row parsing-desiccation.
Embodiment 4
Embodiment 4 with embodiment 1 the difference is that, the freeze drying protectant be maltodextrin.The maltodextrin
Dosage is 5%.
Embodiment 5
Embodiment 5 with embodiment 4 the difference is that, the freeze drying protectant be lactose.The dosage of lactose is 10%.
Embodiment 6
Embodiment 6 with embodiment 4 the difference is that, the freeze drying protectant be beta-cyclodextrin.The dosage of beta-cyclodextrin
It is 10%.
Embodiment 7
Embodiment 7 with embodiment 4 the difference is that, the freeze drying protectant be salt.The dosage of salt is 30%.
Embodiment 8
Embodiment 8 with embodiment 4 the difference is that, the freeze drying protectant be starch.The dosage of starch is 30%.
Embodiment 9
Embodiment 9 with embodiment 4 the difference is that, the freeze drying protectant be sucrose.The dosage of sucrose is 10%.
Embodiment 10
Embodiment 10 with embodiment 1 the difference is that, the freeze drying protectant be beta-cyclodextrin.The dosage of beta-cyclodextrin
It is 30%.
Embodiment 11
Embodiment 11 with embodiment 1 the difference is that, the freeze drying protectant be lactose.Lactose dosage is 5%.
Embodiment 12
A kind of fruit of Cherokee rose standard decoction freeze-dried powder, the freeze-dried powder prepared according to above-mentioned technique.The freeze-dried powder it is aqueous
Rate is 2.58%, catechin content 0.088%.Catechin has antitumor, anti-oxidant, Anti-bacterium and protection heart and brain organ etc.
A variety of effects, freeze-dried products can protect the catechin in fruit of Cherokee rose standard decoction to greatest extent.According to above-mentioned freeze-drying
In freeze-dried powder made from technique, catechin 0.088%, effect is best when moisture content is 2.58%, yield highest.
Embodiment 13
Embodiment 13 with embodiment 12 the difference is that, the moisture content of the freeze-dried powder is 2.43%, and catechin content is
0.144%。
Embodiment 14
Embodiment 14 with embodiment 12 the difference is that, the moisture content of the freeze-dried powder is 3.69%, and catechin content is
0.133%。
Embodiment 15
Embodiment 15 with embodiment 1 the difference is that, take fruit of Cherokee rose standard decoction 1ml.
Embodiment 16
Embodiment 16 with embodiment 1 the difference is that, take fruit of Cherokee rose standard decoction 5mL.
Comparative example 1
Comparative example 1 with embodiment 1 the difference is that, freeze drying protectant is added without in freezing dry process.
Comparative example 2
Comparative example 2 with embodiment 1 the difference is that, take fruit of Cherokee rose standard decoction 2mL, 40% freeze drying protectant be added, freeze
Freeze-dried powder can be obtained after drying.
Comparative example 3
Comparative example 3 with embodiment 1 the difference is that, the density of the fruit of Cherokee rose standard decoction is 0.9g/mL.
Comparative example 4
Comparative example 4 with embodiment 1 the difference is that, the freeze drying protectant be glucose.
Comparative example 5
Comparative example 5 with embodiment 1 the difference is that, the density of the fruit of Cherokee rose standard decoction is 1.2g/mL.
Experimental example 1
It is specific to score using state, freeze-drying rate and the hygroscopicity after the appearance of freeze-dried powder, color, grinding as screening and assessment index
Standard is shown in Table 1.It is main to investigate freeze drying protectants and its dosages such as sucrose, maltodextrin, lactose, beta-cyclodextrin, salt, it filters out
Best protection agent, appraisal result are shown in Table 3.
Fruit of Cherokee rose standard decoction (lot number: S1803048, density: 1g/mL) 2mL is drawn, sets in 10mL cillin bottle, uniformly puts
It is placed in freeze dryer, is lyophilized by " 2.1.3 " freeze-drying curve.
1 freeze-dried powder Score index of table
2 freeze drying protectant evaluation result of table
According to the experimental results, protectant freeze-dried powder is not added and severe atrophy occurs, viscosity is big, can not carry out follow-up study；Wheat
The freeze-dried powder surfacing of bud dextrin group, uniform color, freeze-dried powder viscosity are small；It slightly wrinkles on the freeze-dried powder surface of beta-cyclodextrin group
Contracting, is partially layered；There is different degrees of collapse and shrinkage in the freeze-dried powder of starch group；The freeze-dried powder of sucrose group occurs serious
Spray bottle；The freeze-dried powder surfacing of salt group, in addition to additional amount is 30%, remaining layering is obvious；The freeze-dried powder of lactose group adds
Enter that the case where amount is 5% and 10% is preferable, remaining occurs different degrees of collapsing and being layered.
Experimental example 2
Freeze-drying rate, hygroscopicity and catechin content measurement are carried out to the freeze-dried powder that embodiment and comparative example obtain, screened best real
Apply a scheme.
The measurement of 2.1 freeze-drying rates: freeze-drying rate is the ratio that dehydration quality accounts for sample moisture total amount after sample is lyophilized.Calculation formula
Are as follows: freeze-drying rate=100%- moisture content %.The preferable freeze-dried powder of effect in embodiment and comparative example is chosen, according to " middle traditional Chinese medicines
Allusion quotation " moisture analysis in general rule 0832, calculate water content in test sample.
The measurement of 2.2 hygroscopicity: high humidity drier is set in each 4g of sample in embodiment and comparative example, accurately weighed weight, opening
Interior (relative humidity is 85% in drier at this time) 4.5 hours.Record solid masses after each sample moisture absorption.
The measurement of 2.3 catechin contents: sample about 0.1g in Example and comparative example, it is accurately weighed, it is placed in tool plug taper
In bottle, 50% methanol 10mL, weighed weight is added, ultrasonic treatment (power 250W, frequency 40kHz) 30 minutes is let cool, then weighed
Weight is supplied the weight of less loss with 50% methanol, is shaken up, and filters through 0.22 μm of filter membrane, takes subsequent filtrate to obtain the final product.Carry out gas-chromatography
Analysis, chromatographic condition are as follows: chromatographic column be Agilent SB C18(2.1 × 100mm, 1.8 μm), column temperature: 30 DEG C, sample volume: 1 μ
L, volume flow: 0.3mL/min, Detection wavelength: 202nm, mobile phase A are acetonitrile；B is 0.1% phosphate aqueous solution, binary gradient
Elution: 0 ~ 12min, 4% ~ 8%A；12 ~ 19min, 8% ~ 11%A.
Evaluation result is shown in Table 3.
The performance of the freeze-dried powder of each embodiment of table 3
| Evaluation result | Freeze-drying rate (%) | Hygroscopicity (g) | Catechin content | |
| Embodiment 1 | 25 | 97.42 | 0.0307 | 0.031 |
| Embodiment 2 | 20 | 91.14 | 0.0254 | 0.036 |
| Embodiment 3 | 21 | 92.36 | 0.0365 | 0.022 |
| Embodiment 4 | 19 | 92.86 | 0.0291 | 0.030 |
| Embodiment 5 | 22 | 91.38 | 0.019 | 0.022 |
| Embodiment 6 | 20 | 93.03 | 0.0329 | 0.030 |
| Embodiment 7 | 23 | 93.49 | 0.0423 | 0.017 |
| Embodiment 8 | 16 | 88.23 | 0.0513 | 0.008 |
| Embodiment 9 | 12 | 89.23 | 0.0482 | 0.003 |
| Embodiment 10 | 20 | 92.85 | 0.0462 | 0.032 |
| Embodiment 11 | 22 | 91.46 | 0.0248 | 0.035 |
| Comparative example 1 | 16 | 90.72 | 0.0205 | 0.036 |
| Comparative example 2 | 19 | 91.32 | 0.0310 | 0.029 |
| Comparative example 3 | 15 | 92.32 | 0.0323 | 0.028 |
| Comparative example 4 | 16 | 88.21 | 0.0432 | 0.028 |
| Comparative example 5 | 14 | 89.98 | 0.0431 | 0.026 |
As can be known from the above table, the appraisal result being added in the embodiment 1 ~ 4 of maltodextrin is higher, and the appraisal result of embodiment 1 is most
It is high, it is seen then that maltodextrin can effectively improve the quality of freeze-dried powder product as freeze drying protectant.Lactose in embodiment 5 ~ 7,
When salt, beta-cyclodextrin are as protective agent, appraisal result is also higher, shows that it can also promote the quality of freeze-dried powder, embodiment 8
Using starch, sucrose as protective agent in ~ 9, appraisal result is lower, and the appraisal result of embodiment 9 is even lower than comparative example 1, table
Bright sugarcane sugar and starch is poor as protectant effect.Comparative example 4 selects glucose as protective agent, and effect is poor, can not
Promote the quality of product.
The freeze-drying rate of embodiment 1,3,4,7,10 is higher, has been more than 92%, is higher than comparative example 1, wherein embodiment 1,3,4
Maltodextrin has been all made of as protective agent, has shown that maltodextrin also has comparable effect for the effect for promoting product.
It joined protective agent in embodiment, the hygroscopicity of freeze-dried powder may improve, and influence the quality of product.Embodiment 3,
The raising of the hygroscopicity of embodiment 7 ~ 10 and comparative example 3 ~ 5 is larger, while finding during the experiment, the freeze-drying in embodiment 3 and 7
Weight is continuously increased powder under experimental conditions, and effect is poor, and therefore, the maltodextrin or salt of excessive concentrations may result in
Deterioration in quality.The dosage of freeze drying protectant in comparative example 2 is excessive, will lead to auxiliary material and is not completely dissolved, catechin contains
Amount decline.
The standard decoction of comparative example 3 and comparative example 5 is different with embodiment 1, freeze-dried powder made from effect after addition protective agent
Quality is general, and showing that the technical solution of the application is particularly suitable for will be that the standard decoction that density is 1g/mL is prepared as freeze-dried powder.
The content of catechin is higher in embodiment 1, is preferably embodiment.
Freeze-dried powder quality is more excellent in embodiment 1,2,4, freeze-drying rate is higher, hygroscopicity promotes smaller, catechin content mean value
Mean value highest in various embodiments.Show using maltodextrin as protective agent, is added in range different 1 ~ 10%, it can
With obtain the preferable freeze-drying prods of quality.And remaining protective agent then needs the protectant dosage of more stringent control, tool
There is certain difficulty in body application.
Freeze-dried powder product quality in embodiment 6 and 10 is also preferable, but its evaluation result is poor, and hygroscopicity fluctuation is larger,
Only freeze-drying rate is just higher under 30% dosage, but hygroscopicity is again significant under 30% dosage improves.Therefore β-ring
Dextrin is general as protectant effect.
The dosage of freeze drying protectant is more in embodiment 7 ~ 8, and partial supplementary material is caused not dissolve completely, to reduce production
Quality.
The amount of the standard decoction dispensed in embodiment 15 and 16 is different, will not influence hygroscopicity, only will affect freeze-drying rate,
Embodiment 15 is easier to be lyophilized but reduce freeze-drying amount when primary operation, yield decline；Embodiment 16 can make the water of freeze-dried powder
Divide and promoted obviously, freeze-drying rate is remarkably decreased.Freeze-drying rate is 97% in embodiment 15, and freeze-drying rate is 86% in embodiment 16.
To sum up, freeze-dried powder in embodiment 1 is best in quality, freeze-drying rate is higher, hygroscopicity promotes smaller, catechin content most
Height is optimal embodiment.
Above-listed detailed description is illustrating for possible embodiments of the present invention, and above embodiments are not to limit this
The scope of the patents of invention, all equivalence enforcements or change without departing from carried out by the present invention, is intended to be limited solely by the scope of the patents of this case.
Claims (10)
1. a kind of production technology of fruit of Cherokee rose standard decoction freeze-dried powder, which is characterized in that take the fruit of Cherokee rose 1 ~ 5mL of standard decoction, add
Enter 1 ~ 30% freeze drying protectant, freeze-dried powder can be obtained after freeze-drying.
2. a kind of production technology of fruit of Cherokee rose standard decoction freeze-dried powder according to claim 1, which is characterized in that described
Freeze drying protectant be sucrose, maltodextrin, lactose, beta-cyclodextrin, salt, starch it is one of or several.
3. a kind of production technology of fruit of Cherokee rose standard decoction freeze-dried powder according to claim 2, which is characterized in that described
Freeze drying protectant is maltodextrin, and the dosage of the maltodextrin is 10%.
4. a kind of production technology of fruit of Cherokee rose standard decoction freeze-dried powder according to claim 1, which is characterized in that described
The density of fruit of Cherokee rose standard decoction is 1g/mL.
5. a kind of production technology of fruit of Cherokee rose standard decoction freeze-dried powder according to claim 1, which is characterized in that described
The solidification point of freeze-drying is -55 ~ -45 DEG C, and the freeze-off time is no less than 2 ~ 4h；After freezing, risen in 5 ~ 10min
Temperature is to -40 ~ -32 DEG C, after maintaining 15 ~ 25h, is warming up to -33 ~ -28 DEG C, maintains 15 ~ 20h；It is warming up to -25 ~ -15 DEG C again, maintains 5
~ 15h is continuously heating to -15 ~ -5 DEG C, maintains 3 ~ 10h；It is warming up to 20 ~ 35 DEG C in 5 ~ 10min, carries out parsing-desiccation.
6. a kind of production technology of fruit of Cherokee rose standard decoction freeze-dried powder according to claim 5, which is characterized in that described
The solidification point of freeze-drying is -50 ~ -45 DEG C, and the freeze-off time is no less than 3 ~ 4h；After freezing, risen in 8 ~ 10min
Temperature is to -35 ~ -32 DEG C, after maintaining 20 ~ 25h, is warming up to -30 ~ -28 DEG C, maintains 18 ~ 20h；It is warming up to -20 ~ -15 DEG C again, maintains
10 ~ 15h is continuously heating to -10 ~ -5 DEG C, maintains 5 ~ 10h；It is warming up to 30 ~ 35 DEG C in 8 ~ 10min, carries out parsing-desiccation.
7. a kind of production technology of fruit of Cherokee rose standard decoction freeze-dried powder according to claim 6, which is characterized in that described
The solidification point of freeze-drying is -50 DEG C, and the freeze-off time is no less than 3h；After freezing, -35 are warming up in 8min
DEG C, after maintaining 20h, -30 DEG C are warming up to, maintains 18h；It is warming up to -20 DEG C again, maintains 10h, is continuously heating to -10 DEG C, maintains
5h；It is warming up to 30 DEG C in 8min, carries out parsing-desiccation.
8. a kind of fruit of Cherokee rose standard decoction freeze-dried powder, which is characterized in that described in any item technique system according to claim 1 ~ 7
Standby freeze-dried powder.
9. a kind of fruit of Cherokee rose standard decoction freeze-dried powder according to claim 8, which is characterized in that the freeze-dried powder contains
Water rate is 2 ~ 4%, and catechin content is 0.005 ~ 0.15%.
10. a kind of fruit of Cherokee rose standard decoction freeze-dried powder according to claim 9, which is characterized in that the freeze-dried powder
Moisture content is 2.58%, catechin content 0.088%.
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