CN109357332A - Cleaning operation area control of microorganisms system and its application method - Google Patents
Cleaning operation area control of microorganisms system and its application method Download PDFInfo
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- CN109357332A CN109357332A CN201811056977.XA CN201811056977A CN109357332A CN 109357332 A CN109357332 A CN 109357332A CN 201811056977 A CN201811056977 A CN 201811056977A CN 109357332 A CN109357332 A CN 109357332A
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F3/00—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
- F24F3/12—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling
- F24F3/14—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by humidification; by dehumidification
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/16—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
- A61L2/20—Gaseous substances, e.g. vapours
- A61L2/202—Ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2/00—Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
- A61L2/24—Apparatus using programmed or automatic operation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L9/00—Disinfection, sterilisation or deodorisation of air
- A61L9/015—Disinfection, sterilisation or deodorisation of air using gaseous or vaporous substances, e.g. ozone
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F11/00—Control or safety arrangements
- F24F11/89—Arrangement or mounting of control or safety devices
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F13/00—Details common to, or for air-conditioning, air-humidification, ventilation or use of air currents for screening
- F24F13/28—Arrangement or mounting of filters
-
- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F3/00—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems
- F24F3/12—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling
- F24F3/16—Air-conditioning systems in which conditioned primary air is supplied from one or more central stations to distributing units in the rooms or spaces where it may receive secondary treatment; Apparatus specially designed for such systems characterised by the treatment of the air otherwise than by heating and cooling by purification, e.g. by filtering; by sterilisation; by ozonisation
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- F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
- F24—HEATING; RANGES; VENTILATING
- F24F—AIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
- F24F8/00—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying
- F24F8/20—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by sterilisation
- F24F8/24—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by sterilisation using sterilising media
- F24F8/26—Treatment, e.g. purification, of air supplied to human living or working spaces otherwise than by heating, cooling, humidifying or drying by sterilisation using sterilising media using ozone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/10—Apparatus features
- A61L2202/14—Means for controlling sterilisation processes, data processing, presentation and storage means, e.g. sensors, controllers, programs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2202/00—Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
- A61L2202/20—Targets to be treated
- A61L2202/25—Rooms in buildings, passenger compartments
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/10—Apparatus features
- A61L2209/11—Apparatus for controlling air treatment
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2209/00—Aspects relating to disinfection, sterilisation or deodorisation of air
- A61L2209/20—Method-related aspects
- A61L2209/21—Use of chemical compounds for treating air or the like
- A61L2209/212—Use of ozone, e.g. generated by UV radiation or electrical discharge
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/20—Air quality improvement or preservation, e.g. vehicle emission control or emission reduction by using catalytic converters
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- Engineering & Computer Science (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Combustion & Propulsion (AREA)
- Mechanical Engineering (AREA)
- General Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Apparatus For Disinfection Or Sterilisation (AREA)
- Disinfection, Sterilisation Or Deodorisation Of Air (AREA)
Abstract
The present invention relates to clearer production technology fields, disclose cleaning operation area control of microorganisms system, including clean air conditioner, ozone generator, ozone concentration detector and controller.Ozone is sent into the wind pipe of clean air conditioner by ozone generator；Ozone concentration detector is arranged in cleaning operation area；Controller is connect with clean air conditioner, ozone generator and ozone concentration detector signal.The invention also discloses the application methods of the system: 1) closing the fresh air supplement of clean air conditioner, ozone is sent into the disinfection of cleaning operation area by wind pipe, keeps ozone concentration to be not less than 10ppm, the time is not shorter than 0.5 hour；2) the fresh air supplement for opening clean air conditioner is sent into clean air to cleaning operation area, and temperature is maintained≤30 DEG C, relative humidity maintenance≤65%.The system can carry out dynamic disinfection to cleaning operation area using ozone, and this method Disinfection Effect is good, can monitor in real time to disinfection situation, can reach the requirement of cleaning operation area cleannes.
Description
Technical field
The present invention relates to clearer production technology fields, and in particular to a kind of cleaning operation area control of microorganisms system and one kind
The method for controlling cleaning operation area microorganism.
Background technique
In GB14881-2013 " food production general sanitary specification ", it is based on Food Quality and Safety, to food production ring
Border has given code requirement, and food production region is divided into " cleaning operation area ", " quasi- cleaning operation area ", " general job area ",
And specific code requirement is given to the microbiological condition of all kinds of operating areas.
In GMP2010 editions, it is based on drug characteristic, production area is classified, tetra- grades of A, B, C, D are divided into, and
Specify microbiological condition requirement in each rank.Corresponding sanitary condition requires to be shown in Table 1:
Table 1: the dynamic standard of clean area microorganism monitoring
Clean area required by food, pharmaceutical industries has higher requirement to the control of microorganism.The growth of microorganism is numerous
It grows, it is related with the water activity of the damp condition of environment, product；Based on this, the control of the environmental microorganism in clear production region,
Need to keep the microbial environment in clear production region from control ambient humidity, offer pure air.
Most classic Environmental microorganism control mode is to use potassium permanganate, formaldehyde fumigation, Gao Meng by the way of stifling
After sour potassium is mixed with formaldehyde, formaldehyde quickly volatilizees under the action of strong oxidizer potassium permanganate, generates formaldehyde vapor, is come with this
Kill pathogenic microorganism in environment.But formaldehyde has carcinogenic toxicity, so this method was substituted later.It is smoked that there are also chlorine dioxide
Steaming method: using the Strong oxdiative characteristic of chlorine dioxide, to carry out disinfection to environment.But it is met water and is also easy to produce hypochlorous acid, and then decomposes
The residual of chlorine is generated, polluted product and environment, use environment are gradually limited to.Also there is Peracetic acid fumigating system: by A liquid
(glacial acetic acid, the concentrated sulfuric acid) mixes post activation with B liquid (Peracetic acid), is subsequently poured into the container of each point in clear production region
In, heating and gasifying is to environment disinfected.Peracetic acid has strong oxidizing property, and disinfecting power is strong, but has deep-etching to installations and facilities
Property, use environment has biggish limitation.
In May, 2017, Hu Chuanhong et al. propose I grade of Sterile surgery room sterilization method (application publication number CN of one kind
107198784 A), ethyl alcohol first is sprayed to operation flooring and wall, then disappeared for the first time with being dried with nitrogen containing ozone
Poison；Secondary sterilization is carried out with the appropriative disinfector containing chlorine dioxide, sodium trichloro-isocyanurate again；Ultraviolet disinfection light irradiation is used again
Sterilization method, the requirement of I grade of clean operating room can be reached.Not only program is complicated for this method, but also also uses chlorine dioxide
Equal traditional disinfections agent can leave residual chlorine in production environment, it is impossible to be used in the demanding production environment of residual chlorine.
And all these sterilization methods, it is the method for one " static state disinfection ", that is, require in disinfecting process
Keep clear area (clean area) in air do not flow, so as to antiseptic sterilization agent evaporation generate gas entire section loss more
It is unrestrained, the bacterium in section, virus are killed.Which results in disinfectants not can enter air filter, inside equipment
The air inlet of small space and air-conditioning, return air duct kill microorganism.Affect the effect of disinfection.
Under normal conditions, for cleaning operation area control of microorganisms effect, by naked dish detection " in cleaning operation area
Settling bacteria ", while " air sampler " being utilized to sample, " flcating germ " is detected in cleaning operation area with the method for " plate count "
Quantity, the control of microorganisms situation in cleaning operation area is evaluated with " settling bacteria ", " flcating germ " two indices.
But this method is a kind of verifying of lag, evaluation method, since " naked dish detection " and " plate count " needs
Microculture is carried out, and the time that microculture needs is very long, this results in production to have begun or be over life
It produces, whether Environmental microorganism control when can just obtain production meets production requirement, cannot obtain environmental microorganism condition in time
Whether the instruction of production requirement is met.Once deviation occur in environmental factor slight change or the operation of people, production band will be given
Carry out very big risk.
Summary of the invention
The purpose of the invention is to overcome prior art disinfectant to generate adverse consequences, " static state disinfection " Disinfection Effect compared with
Difference problem, a kind of cleaning operation area control of microorganisms system is provided, by ozone generator clean air conditioner wind pipe
It is passed through ozone, the concentration of operating area ozone is monitored by ozone concentration detector, passes through the operation of controller control system, tool
There is the advantages that Disinfection Effect is good, easy to use.The present invention also provides a kind of method for controlling cleaning operation area microorganism, the party
Method utilizes the ozone (O that oxidizing force is strong, penetration power is strong3) environmental unit facility, air are dynamically sterilized, Disinfection Effect
It is good, and ozone is easily decomposes, will not generate residue, will not generate adverse effect to installations and facilities.It can also be dense by ozone
The product (CT value) of degree and time to assess Disinfection Effect in real time.
The method of CT value monitoring Disinfection Effect: ozone sterilizes for environment disinfected, and concentration, action time are to ensure that disinfection
Two parameters of effect, and concentration required for different sterilization objects, action time difference, inventor is by largely trying
It tests, the CT value range of useful effect when groping, summing up the disinfection of cleaning operation area.
For the validity for verifying the value, the method for the present inventor's use " enterobacteria increases bacterium verifying ", to establish having for disinfection
It imitates CT value: in the BPW enriched medium after enterobacteria to be accessed to aseptic process, cultivating 24- in 36 DEG C ± 1 of constant incubator
It 48 hours, is then counted using blood counting chamber, to determine the concentration of enterobacteria in culture medium, then by the bacterium solution in desinfection chamber
It is uniformly applied on the aluminium foil bag of test, then the aluminium foil bag for being coated with bacterium solution is put into test box, it is smelly with 10ppm respectively
Oxygen sterilizes 0.5 hour, 1 hour, 2 hours, 3 hours, 4 hours；The ozonization 0.5 hour of 20ppm, 1 hour, 2 hours, it is 3 small
When, 4 hours and with 30ppm ozonization 0.5 hour, 1 hour, 2 hours, the processing that carries out disinfection in 3 hours, 4 hours, processing terminate
Afterwards using the lethality of the method detection enterobacteria of surface wipes, with the Disinfection Effect of ozone under the various CT values of determination, thus
To CT value needed for this patent method.
To achieve the goals above, the present invention provides a kind of cleaning operation area control of microorganisms systems, including clean sky
Tune, ozone generator, ozone concentration detector and controller.The clean air conditioner has dehumidification thermal-insulating and fresh air supplementary functions；
The efferent duct of the ozone generator is connected to the wind pipe of the clean air conditioner；The ozone concentration detector is arranged clear
The operating area of clean operation area；The controller is believed with the clean air conditioner, ozone generator and ozone concentration detector respectively
Number connection.
Preferably, the ozone concentration detector is provided with multiple, is distributed in the different work region in cleaning operation area.
Preferably, the ozone concentration detector has remote transmission device, and passes through remote transmission device and the controller signals
Connection；The controller is PLC.
Preferably, cleaning operation area control of microorganisms system of the invention further includes host computer, and the controller is with upper
Position machine interface, connect with the host computer signal.
Preferably, the clean air conditioner include fresh air inlet, return air inlet, blower, medium effeciency filter, thermostat unit,
Humidity adjustment unit, high efficiency particulate air filter and air outlet；The fresh air inlet and the return air inlet are communicated to the blower, and air exists
The medium effeciency filter, the thermostat unit, the humidity adjustment unit and institute are passed sequentially through under the action of the blower
High efficiency particulate air filter is stated, is discharged by the air outlet.
The present invention also provides a kind of methods for controlling cleaning operation area microorganism, comprising the following steps:
1) the fresh air supplementary functions of the clean air conditioner are closed, it is by the wind pipe that ozone is uninterrupted through circulated air
It is sent into the cleaning operation area to carry out disinfection, keeps the ozone concentration in the cleaning operation area not less than 10ppm, the time is not short
In 0.5 hour；
2) the fresh air supplementary functions for opening the clean air conditioner are sent at through the clean air conditioner to the cleaning operation area
The clean air comprising fresh air of reason, and the temperature in the cleaning operation area maintained≤30 DEG C, relative humidity maintains
≤ 65%.Supplement fresh air can quickly reduce the concentration of ozone in the cleaning operation area, relative low temperature, low humidity environment can inhibit
The growth of microorganism.
Preferably, in the step 1), keeping the ozone concentration in the cleaning operation area is 30ppm.
Preferably, it in the step 1), monitors in real time, comment by ozone concentration and the product of duration (CT value)
Estimate practical Disinfection Effect, the product of ozone concentration and duration are controlled in 9000-14400mg/m3min。
Preferably, the cleaning operation area is for food, health care product or the cleaning operation of pharmaceutical production area.
Through the above technical solutions, cleaning operation area control of microorganisms system of the invention, not only realizes dynamic disinfection
Process, can be to realizing pasteurised completely inside air filter, air-conditioning duct and equipment, and imitated using the disinfection of ozonization
Fruit is good, not damaged to installations and facilities, will not leave any Environmental Residues.The side of control cleaning operation area microorganism of the invention
Method can guarantee the ozone concentration and disinfecting time in cleaning operation area different work region；Each operation is monitored in real time by CT value
The Disinfection Effect in region can monitor and adjust the disinfection situation in cleaning operation area in real time, guarantee Disinfection Effect；After disinfection
Ozone concentration can be quickly reduced in the case where keeping cleannes, entered convenient for staff；The environment of constant temperature low humidity can
The growth of microorganism is controlled, conducive to the cleannes for keeping cleaning operation area.
Detailed description of the invention
Fig. 1 is cleaning operation area control of microorganisms system schematic of the invention；
Fig. 2 is the CT figure of the method for control cleaning operation area microorganism of the invention.
Description of symbols
1 clean air conditioner, 2 ozone occurs
3 controller, 4 ozone concentration detector
5 host computer, 6 cleaning operation area
7 wind pipe, 8 return air duct
11 fresh air inlet, 12 return air inlet
13 blower, 14 medium effeciency filter
15 thermostat unit, 16 humidity adjustment unit
17 high efficiency particulate air filter, 18 air outlet
61 production district, 62 bagging area
63 material storage areas
Specific embodiment
A specific embodiment of the invention is described in detail below in conjunction with attached drawing, it should be appreciated that this place
The specific embodiment of description is merely to illustrate and explain the present invention, and protection scope of the present invention is not limited to following specific
Embodiment.
Cleaning operation area control of microorganisms system of the invention as shown in Figure 1, include clean air conditioner 1, ozone generator 2,
Ozone concentration detector 4, controller 3 and host computer 5.
Clean air conditioner 1 include fresh air inlet 11, return air inlet 12, blower 13, medium effeciency filter 14, thermostat unit 15,
Humidity adjustment unit 16, high efficiency particulate air filter 17 and air outlet 18.Fresh air inlet 11 has primary filter, together with return air inlet 12
It is communicated to blower 13, air passes sequentially through medium effeciency filter 14, thermostat unit 15, humidity regulation under the action of blower 13
Unit 16 and high efficiency particulate air filter 17 are discharged by air outlet 18.Air outlet 18 is connected to cleaning operation area 6 by wind pipe 7,
Cleaning operation area 6 includes production district 61, bagging area 62 and material storage area 63, and wind pipe 7 is connected respectively to production district 61, packet
Dress area 62 and material storage area 63, production district 61, bagging area 62 and material storage area 63 are connected to back by return air duct respectively
Air port 12.The efferent duct of ozone generator 2 is connected to wind pipe 7, and generated ozone enters production district by wind pipe 7
61, bagging area 62 and material storage area 63 carry out disinfection；Pass through return air in production district 61, bagging area 62 and material storage area 63
Pipeline 8 is connected to return air inlet 12.It is placed at the separate air inlet position of production district 61, bagging area 62 and material storage area 63
Ozone concentration detector 4, ozone concentration detector 4 are had remote using the detector of the model MOT500-O3 of Switzerland's production
Device is passed, for detecting the ozone concentration of production district 61, bagging area 62 and material storage area 63, and is transmitted to by remote transmission device
Controller 3, controller 3 are connected using the S7 200PLC of Siemens Company by host computer interface and the host computer communication of S7 200
It connects, host computer uses Dell's industrial personal computer.Controller 3 is also connect with clean air conditioner 1 and 2 signal of ozone generator respectively, is controlled clean
The working condition of headroom tune 1 and ozone generator 2.
In the type selecting standard for the ozone generator that cleaning operation area control of microorganisms system of the invention uses are as follows: ozone produces
Raw amount Q (mg/h)=disinfection concentration (mg/m3) × (workshop volume (m3)+fresh air supplements volume (m3)) ÷ ozone attenuation coefficient S
(0.428), suitable ozone generator is selected with this.The range of MOT500-O3 ozone concentration detector: 0-100ppm.
It is as follows in the course of work of cleaning operation area control of microorganisms system of the invention:
Under disinfection mode, controller 3 controls clean air conditioner 1 and closes fresh air inlet 11, carries out interior by return air inlet 12
Air circulation.Room air is removed empty under the action of blower 13, into return air inlet 12 by the filtering of medium effeciency filter 14
Smaller dust in gas；Into thermostat unit 15, thermostat unit 15 adjusts temperature to set temperature；Pass through humidity
Unit 16 is adjusted by the humidity of air humidity adjusting to setting；Small dust, bacterium and bud are removed by high efficiency particulate air filter 17
Born of the same parents etc.；Enter wind pipe 7 by air outlet 18.Controller 3 opens ozone generator 2 simultaneously, is sent into wind pipe 7 smelly
Oxygen.Air containing ozone respectively enters three operating areas in cleaning operation area 6: production district 61, packaging by wind pipe 7
Area 62 and material storage area 63, in production district 61, bagging area 62 and material storage area 63 equipment and air carry out disinfection, it is raw
Air in producing region 61, bagging area 62 and material storage area 63 is recycled by return air duct 8.Meanwhile production district 61, packaging
Ozone concentration detector 4 in area 62 and material storage area 63 detects production district 61, bagging area 62 and material storage area 63 respectively
In ozone concentration, and by data remote to controller 3；Controller 3 is by various data information transfers to host computer 5, host computer 5
The concentration-time figure (as shown in Figure 2) and CT value for generating each operating area monitor disinfection shape for production technology, administrative staff
State.Meanwhile controller 3 adjusts ozone generator according to setting concentration and the value of the ozone concentration of each operating area detected
2 produce ozoniferous amount is opened when the ozone concentration in operating area reaches setting value with controlling the ozone concentration of each operating area
Begin to calculate disinfecting time and CT value.Ozone generator 2 is closed when CT value in each operating area reaches setting value, is opened new
Wind entrance 11, cleaning operation area control of microorganisms system exit disinfection mode, into the mode of maintenance.
Under maintenance mode, fresh air inlet 11 is opened, and clean air conditioner 1 is entered while through 12 return air of return air inlet by fresh air
Mouth 11 fills into the fresh air by primary filter, temperature adjustment, damping in clean air conditioner 1, and effect, high efficiency particulate air filter filtering in warp
Afterwards, the clean air of constant temperature and humidity enters wind pipe 7 by air outlet 18, and enters cleaning operation area by wind pipe 7
6,6 ozone concentration rapid decrease of cleaning operation area, and maintain germ-free condition.The air pressure in cleaning operation area 6 is in barotropic state, part
Air is recycled by the return air inlet 12 that return air duct 8 enters clean air conditioner, and partial air is escaped from cleaning operation area 6.Clearly
The healthy tendency pressure condition of clean operation area 6 helps to maintain the cleannes in cleaning operation area 6.
Several embodiments of the method for control cleaning operation area microorganism of the invention are given below, in all embodiments
Cleaning operation area control of microorganisms system is all made of the specific implementation gone out given in above embodiment.Terminate in disinfection
Afterwards, before production starting, the micro- life of equipment surface is carried out by national standard standard method sample detection flcating germ and wiping device surface
The verifying of the detection of object.
Embodiment 1
1) after clean area equipment, plant cleanliness, the fresh air inlet 11 of cleaning air-conditioning 1 is closed, stops fresh air supplement, opens
Ozone generator 2 is opened, ozone is sent into the air in cleaning operation area 6 by the wind pipe 7 of cleaning air-conditioning 1, in each work
The detected value of the ozone concentration detector 4 in industry region starts timing when reaching 25ppm.
2) reach 12000mg/m in the CT value of ozonization3When min, stops ozone generator 2 and work, open cleaning
The clean air that the supplement of fresh air inlet 11 of air-conditioning 1 is handled by cleaning air-conditioning 1.
3) by the constant temperature and humidity function of cleaning air-conditioning, the temperature in cleaning operation area is controlled in 25 DEG C, relative humidity control
System is 30%.
Embodiment 2
1) after clean area equipment, plant cleanliness, the fresh air inlet 11 of cleaning air-conditioning 1 is closed, stops fresh air supplement, opens
Ozone generator 2 is opened, ozone is sent into the air in cleaning operation area 6 by the wind pipe 7 of cleaning air-conditioning 1, in each work
The detected value of the ozone concentration detector 4 in industry region starts timing when reaching 20ppm.
2) reach 9000mg/m in the CT value of ozonization3When min, stops ozone generator 2 and work, it is empty to open cleaning
1 supplement of fresh air inlet 11 is adjusted to pass through the clean air that cleaning air-conditioning 1 is handled.
3) by the constant temperature and humidity function of cleaning air-conditioning, the temperature in cleaning operation area is controlled in 24 DEG C, relative humidity control
System is 15%.
Embodiment 3
1) after clean area equipment, plant cleanliness, the fresh air inlet 11 of cleaning air-conditioning 1 is closed, stops fresh air supplement, opens
Ozone generator 2 is opened, ozone is sent into the air in cleaning operation area 6 by the wind pipe 7 of cleaning air-conditioning 1, in each work
The detected value of the ozone concentration detector 4 in industry region starts timing when reaching 30ppm.
2) reach 14400mg/m in the CT value of ozonization3When min, stops ozone generator 2 and work, open cleaning
The clean air that the supplement of fresh air inlet 11 of air-conditioning 1 is handled by cleaning air-conditioning 1.
3) by the constant temperature and humidity function of cleaning air-conditioning, the temperature in cleaning operation area is controlled in 26 DEG C, relative humidity control
System is 45%.
Embodiment 4
1) after clean area equipment, plant cleanliness, the fresh air inlet 11 of cleaning air-conditioning 1 is closed, stops fresh air supplement, opens
Ozone generator 2 is opened, ozone is sent into the air in cleaning operation area 6 by the wind pipe 7 of cleaning air-conditioning 1, in each work
The detected value of the ozone concentration detector 4 in industry region starts timing when reaching 10ppm.
2) reach 10000mg/m in the CT value of ozonization3When min, stops ozone generator 2 and work, open cleaning
The clean air that the supplement of fresh air inlet 11 of air-conditioning 1 is handled by cleaning air-conditioning 1.
3) by the constant temperature and humidity function of cleaning air-conditioning, the temperature in cleaning operation area is controlled in 30 DEG C, relative humidity control
System is 65%.
Reference examples
1) after clean area equipment, plant cleanliness, cleaning air-conditioning 1 is closed, in each operating area in cleaning operation area 6
The plate for placing 2-4 loading 20ml, 200ppm ClO 2 solution, is fumigated 120 minutes.
2) cleaning air-conditioning 1 is opened, is 25 DEG C by the temperature setting in cleaning operation area 6, is supplemented and passed through by fresh air inlet 11
Clean the clean air that air-conditioning 1 is handled.
After stifling, production starting before, by national standard method detection aerial bacterioplankton and wiping device surface into
Row equipment surface microorganism detection.
The testing result of all embodiments and reference examples is shown in Table 2 and table 3.
Table 2: cleaning operation area air microbe Indexs measure result
Table 3: equipment surface microorganism wipes testing result: a/25cm2
It can be seen that from the testing result of table 2 compared to reference examples, using control cleaning operation area microorganism of the invention
Method embodiment air in flcating germ and settling bacteria clump count it is less, and produce 5 days after microbes in air quantity
Increase it is also slower.It can be seen that from the testing result of table 3 compared to reference examples, using control cleaning operation area of the invention
The micro organism quantity of the embodiment equipment surface of the method for microorganism is less, the micro organism quantity of equipment surface after production 5 days
Less, the method for control cleaning operation area microorganism of the invention has the effect of more obvious disinfection and inhibition microbial growth
Fruit.The method of control cleaning operation area microorganism of the invention can be applied to the cleaning of food, health care product or pharmaceutical production field
The control of operation area environmental microorganism.
The preferred embodiment of the present invention has been described above in detail, and still, the present invention is not limited thereto.In skill of the invention
In art conception range, can with various simple variants of the technical solution of the present invention are made, including each technical characteristic with it is any its
Its suitable method is combined, and it should also be regarded as the disclosure of the present invention for these simple variants and combination, is belonged to
Protection scope of the present invention.
Claims (9)
1. a kind of cleaning operation area control of microorganisms system, which is characterized in that including clean air conditioner (1), ozone generator (2),
Ozone concentration detector (4) and controller (3)；
The clean air conditioner (1) has dehumidification thermal-insulating and fresh air supplementary functions；The efferent duct of the ozone generator (2) is connected to
The wind pipe (7) of the clean air conditioner (1)；Operation area of ozone concentration detector (4) setting in cleaning operation area (6)
Domain；The controller (3) connects with the clean air conditioner (1), ozone generator (2) and ozone concentration detector (4) signal respectively
It connects.
2. cleaning operation area control of microorganisms system according to claim 1, which is characterized in that the ozone concentration detection
Instrument (4) is provided with multiple, is distributed in the different work region in cleaning operation area (6).
3. cleaning operation area control of microorganisms system according to claim 1 or 2, which is characterized in that the ozone concentration
Detector (4) has remote transmission device, and is connect by remote transmission device with the controller (3) signal；The controller (3) is
PLC。
4. cleaning operation area control of microorganisms system according to claim 1 or 2, which is characterized in that further include host computer
(5), the controller (3) has host computer interface, connect with the host computer (5) signal.
5. cleaning operation area control of microorganisms system according to claim 1, which is characterized in that the clean air conditioner (1)
Including fresh air inlet (11), return air inlet (12), blower (13), medium effeciency filter (14), thermostat unit (15), humidity regulation
Unit (16), high efficiency particulate air filter (17) and air outlet (18)；Fresh air inlet (11) and return air inlet (12) are communicated to blower (13), empty
Gas passes sequentially through medium effeciency filter (14), thermostat unit (15), humidity adjustment unit (16) under the action of blower (13)
It is discharged with high efficiency particulate air filter (17) by air outlet (18).
6. a kind of method for controlling cleaning operation area microorganism, which comprises the following steps:
1) the fresh air supplementary functions for closing clean air conditioner (1), by the wind pipe (7) of clean air conditioner (1) by ozone through recycling
Wind is uninterruptedly sent into cleaning operation area (6) and carries out disinfection, and cleaning operation area (6) ozone concentration is kept to be not less than 10ppm, time
It is not shorter than 0.5 hour；
2) the fresh air supplementary functions for opening clean air conditioner (1), the packet handled through clean air conditioner (1) is sent into cleaning operation area (6)
Clean air containing fresh air, and by the temperature of cleaning operation area (6) maintain≤30 DEG C, relative humidity maintain≤65%.
7. the method for control cleaning operation area microorganism according to claim 6, which is characterized in that in the step 1)
In, keeping the ozone concentration of the cleaning operation area (6) is 30ppm, is held time 1-4 hours.
8. the method for control cleaning operation area microorganism according to claim 6, which is characterized in that in the step 1)
In, monitored in real time by the product of ozone concentration and duration, assess practical Disinfection Effect, by ozone concentration and it is lasting when
Between product control in 9000-14400mg/m3min。
9. according to the method for the described in any item control cleaning operation area microorganisms of claim 6-8, which is characterized in that described clear
Clean operation area (6) is for food, health care product or the cleaning operation of pharmaceutical production area.
Priority Applications (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811056977.XA CN109357332A (en) | 2018-09-11 | 2018-09-11 | Cleaning operation area control of microorganisms system and its application method |
| PCT/CN2019/086317 WO2020052249A1 (en) | 2018-09-11 | 2019-05-10 | Cleaning operation area microorganism control system and use method therefor |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811056977.XA CN109357332A (en) | 2018-09-11 | 2018-09-11 | Cleaning operation area control of microorganisms system and its application method |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2020052249A1 (en) * | 2018-09-11 | 2020-03-19 | 梁云 | Cleaning operation area microorganism control system and use method therefor |
| CN112255983A (en) * | 2020-10-24 | 2021-01-22 | 陈彦均 | Big data processing method and production data processing center based on cosmetic production |
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Also Published As
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| WO2020052249A1 (en) | 2020-03-19 |
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Application publication date: 20190219 |