CN109303801A - A kind of tea bag and preparation method thereof for treating habitual constipation - Google Patents

A kind of tea bag and preparation method thereof for treating habitual constipation Download PDF

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Publication number
CN109303801A
CN109303801A CN201811438554.4A CN201811438554A CN109303801A CN 109303801 A CN109303801 A CN 109303801A CN 201811438554 A CN201811438554 A CN 201811438554A CN 109303801 A CN109303801 A CN 109303801A
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CN
China
Prior art keywords
tea bag
treating
constipation
habitual constipation
radix angelicae
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Pending
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CN201811438554.4A
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Chinese (zh)
Inventor
刘玉龙
林春和
常振
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Lin Bao Pharmaceutical (harbin) Co Ltd
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Lin Bao Pharmaceutical (harbin) Co Ltd
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Priority to CN201811438554.4A priority Critical patent/CN109303801A/en
Publication of CN109303801A publication Critical patent/CN109303801A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/64Orobanchaceae (Broom-rape family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0087Galenical forms not covered by A61K9/02 - A61K9/7023
    • A61K9/009Sachets, pouches characterised by the material or function of the envelope
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/10Laxatives

Abstract

The invention belongs to medicinal herb tea field, and in particular to a kind of tea bag and preparation method thereof for treating habitual constipation.In order to solve the problems, such as and complicated classification excessive there are treatment method and be easy wrong medicine, the invention propose it is a kind of be applicable in a variety of situation constipation therapies for treating tea bag of habitual constipation and preparation method thereof;To achieve the goals above, the technical solution of the invention is that a kind of for treating the tea bag of habitual constipation, he is prepared by the bulk pharmaceutical chemicals extraction of following component: 6-30 parts of Senna leaf, 1-5 parts of Radix Angelicae Sinensis, 1-5 parts of Herba Cistanches;It is prepared by the bulk pharmaceutical chemicals extraction of following deal: 6 parts of Senna leaf, 1 part of Radix Angelicae Sinensis, 1 part of Herba Cistanches.

Description

A kind of tea bag and preparation method thereof for treating habitual constipation
Technical field
The invention belongs to medicinal herb tea field, and in particular to a kind of for treating the tea bag and its system of habitual constipation Preparation Method.
Background technique
There are very big mistaken ideas in many people now on concept in life to constipation, thinks that constipation is minor illness, is unworthy It goes to treat, becomes habitual constipation over time.Constipation other than making patient's difficult defecation, being hard and dry, also with abdominal distension, Abdominal pain, appetite stimulator, stool outside symptom not to the utmost, are also frequently accompanied by insomnia, spirit agitation and the coarse ash of complexion with blood and just Secretly.
Constipation is clinical common disease, and the middle-aged and the old is the common crowd in constipation patient, in addition the people of long-time sitting Group's constipation disease incidence is also increasing year by year.The another patient for suffering from Cardial or cerebral vascular diseases, habitual constipation is caused by aggravation One of factor.
Human body keeps the normal physiological activity of metabolism, disengaging balance when defecation;The waste that the intracorporal metabolism of people generates, Mainly excreted by excrement.Long-term habits constipation, the waste being metabolized in vivo cannot be discharged in time, can induce a variety of diseases Disease is worth everybody to pay attention to health, serious consequence is endangered.
In theory of traditional Chinese medical science, constipation Different types of etiopathogenises causes, and has different types, is equally also required to different treatment Method.In Chinese medicine, it is secret that constipation is divided into real secret and void;It is real secret and to be divided into heat secret gentle secret, it is empty secret and be divided into constipation due to deficiency of vital energy, the deficiency of blood Constipation, treaitng Yin-deficiency constipation and constipation due to endogenous cold;And the cause of disease that every kind of constipation generates is different, if medication is wrong other than it can not solve the problems, such as, Other mutual side effects can also be generated.
Summary of the invention
In order to solve the problems, such as appeal excessive and complicated classification and easy wrong medicine, the invention there are treatment method Propose it is a kind of be applicable in a variety of situation constipation therapies for treating tea bag of habitual constipation and preparation method thereof.
To achieve the goals above, the technical solution of the invention is a kind of bag bubble for treating habitual constipation Tea, he is prepared by the bulk pharmaceutical chemicals extraction of following component: 6-30 parts of Senna leaf, 1-5 parts of Radix Angelicae Sinensis, 1-5 parts of Herba Cistanches.
Preferably, it is prepared by the bulk pharmaceutical chemicals extraction of following component: 6 parts of Senna leaf, 1 part of Radix Angelicae Sinensis, Herba Cistanches 1 Part.
Preferably, a kind of production method for treating the tea bag of habitual constipation, is suitable for as described above one It plants the tea bag for treating habitual constipation, comprising the following steps: S1: by folium sennae (medicine materical crude slice), setting p-type coarse-cracking machine inner powder It is broken;S2: smashed coarse powder is placed in screening machine, is screened into the medicinal powder of 20-60 mesh;S3: medicinal powder being set in clean container, inspection Microbial limit is tested, is put in storage after the assay was approved spare;S4: will examine qualified cassia angustifolia leaf coarse powder, Radix Angelicae Sinensis, Herba Cistanches clear cream, point Other precise;S5: load weighted cassia angustifolia leaf coarse powder is set in trough type mixing machine, and dry-mixed 10 minutes;S6: Radix Angelicae Sinensis, Herba Cistanches are clear Cream is uniformly added into, and is stirred 10 minutes;S7: mixed cream powder mixture is laid in stainless steel screen tray, is placed and is dried It is dry in case;S8: dried cream powder mixture is crossed into 14 meshes through oscillating granulator whole grain, sets in multinomial mixing machine and mixes 20 minutes, it is to be tested that it is sent into intermediate station after mixing;S9: tea bag after the assay was approved is dispensed with tea bag racking machine;S10: every Bag 2.5g, tea filter paper used, Key works Drug packing polyester aluminized complex film should meet inner packaging material specification standards, and every 10 minutes Monitor a loading amount;S11: the tea bag dispensed is sent into intermediate station;S12: by batch packaging directive to capsule, middle box, big case The lot number of upper print, the date of manufacture, valid until etc. information.
Preferably, be laid in the S7 in stainless screen tray, spread with a thickness of every disk 1.5-2.5cm.
Preferably, being placed in drying in baking oven in the S7, drying temperature is 50 DEG C of -60 ° of degree, drying time It is 120 minutes;And the oven temperature of detection in every 10 minutes, by moisture control below 10.0%.
Preferably, the racking machine of the S9 being previously mentioned, used packing temperature are as follows: horizontal sealing temperature: 130- 155℃;Longitudinal sealing temperature: 110-130 DEG C.
Preferably, this product common name are as follows: Rong lets out constipation-relieving tea also known as defaecation spirit tea.
The invention the utility model has the advantages that (1) the invention follows the saying of the suitable defaecation of the constipation in theory of traditional Chinese medical science, adopt Use folium sennae as defaecation main ingredient;(2) amount of folium sennae is reduced, together to reduce its pharmacological property for violent medicine due to folium sennae When be aided with and joined Radix Angelicae Sinensis and Herba Cistanches, Radix Angelicae Sinensis and Herba Cistanches have effects that tonic, while also having the effect of profit just leads to intestines, But defaecation only cannot be reached with Radix Angelicae Sinensis and Herba Cistanches, but be only harmful to the health again with folium sennae defaecation, so the invention Three taste medicinal materials are used in combination, reduce the dose of folium sennae, reduce the efficacy of a drug, but are aided with Radix Angelicae Sinensis again and Herba Cistanches are moistened and just lead to Intestines allow to smooth defaecation again and reduce the damage to body, and (3) simultaneously again due to Chinese angelica blood supplementing, Herba Cistanches tonifying Qi will again The vim and vigour that folium sennae takes away are supplemented, so that the damage to body is minimized, and have the effect got instant result;(4) cassia angustifolia Leaf cured mainly as main ingredient it is real secret, this to it is empty it is secret can not play a role, but since this kind joined Radix Angelicae Sinensis and Herba Cistanches, and The dosage of folium sennae is reduced, so that this tea bag has certain effect similarly for treatment void is secret, slow can be reached to slight illness The effect of solution, and side effect will not be generated, it more times goes correctly to select medicine to patient;(5) in production method, S3 can be kept away Exempt from unqualified or other sick hidden danger with infection medicinal materials occur;(6) in S4, it is in order to more that Radix Angelicae Sinensis and Herba Cistanches, which use clear cream, Good mixes with cassia angustifolia leaf coarse powder, is well-known technique as the clear cream preparation method of its Radix Angelicae Sinensis and Herba Cistanches, details are not described herein again; (7) moisture is controlled when dry 10% hereinafter, being to cause to increase to be bonded between particle when drug granule makes Metering, and can also be improved the storage time of drug;(8) horizontal sealing temperature and longitudinal sealing temperature are in the feelings for not influencing internal drug It can to encapsulate strict optimum temperature again under condition.
Specific embodiment
Below with reference to embodiment, the invention will be further described:
It is a kind of for treating the tea bag of habitual constipation, he is prepared by the bulk pharmaceutical chemicals extraction of following component: kind being let out 6-30 parts of leaf, 1-5 parts of Radix Angelicae Sinensis, 1-5 parts of Herba Cistanches.
It is prepared by the bulk pharmaceutical chemicals extraction of following component: 6 parts of Senna leaf, 1 part of Radix Angelicae Sinensis, 1 part of Herba Cistanches.
A kind of production method for treating the tea bag of habitual constipation, suitable for as described above a kind of for treating The tea bag of habitual constipation, comprising the following steps: S1: it by folium sennae (medicine materical crude slice), sets in P type coarse-cracking machine and crushes;S2: it crushes Coarse powder afterwards is placed in screening machine, is screened into the medicinal powder of 20-60 mesh;S3: medicinal powder being set in clean container, examines microorganism Limit is put in storage spare after the assay was approved;S4: will examine qualified cassia angustifolia leaf coarse powder, Radix Angelicae Sinensis, Herba Cistanches clear cream, accurate respectively to claim Amount;S5: load weighted cassia angustifolia leaf coarse powder is set in trough type mixing machine, and dry-mixed 10 minutes;S6: Radix Angelicae Sinensis, Herba Cistanches clear cream are uniformly added Enter, is stirred 10 minutes;S7: mixed cream powder mixture is laid in stainless steel screen tray, is placed and is done with baking oven It is dry;S8: crossing 14 meshes through oscillating granulator whole grain for dried cream powder mixture, sets and mixes 20 points in multinomial mixing machine It is to be tested to be sent into intermediate station after mixing for clock;S9: tea bag after the assay was approved is dispensed with tea bag racking machine;S10: every bag 2.5g, tea filter paper used, Key works Drug packing polyester aluminized complex film should meet inner packaging material specification standards, supervise within every 10 minutes Survey a loading amount;S11: the tea bag dispensed is sent into intermediate station;S12: by batch packaging directive on capsule, middle box, big case The lot number of print, the date of manufacture, valid until etc. information.
Be laid in the S7 in stainless screen tray, spread with a thickness of every disk 1.5-2.5cm.
In the S7, it is placed in drying in baking oven, drying temperature is 50 DEG C -60 DEG C, and drying time is 120 minutes; And the oven temperature of detection in every 10 minutes, moisture is controlled 10.0% once.
The racking machine of the S9 being previously mentioned, used packing temperature are as follows: horizontal sealing temperature: 130-155 DEG C;Longitudinal sealing temperature Degree: 110-130 DEG C.
This product common name are as follows: Rong lets out constipation-relieving tea also known as defaecation spirit tea.
The invention follows the saying of the suitable defaecation of the constipation in theory of traditional Chinese medical science, uses folium sennae as defaecation main ingredient; Since folium sennae reduces the amount of folium sennae for violent medicine in order to reduce its pharmacological property, while being aided with and joined Radix Angelicae Sinensis and Herba Cistanches, Radix Angelicae Sinensis and Herba Cistanches have effects that tonic, while also having the effect of profit just leads to intestines, but only not with Radix Angelicae Sinensis and Herba Cistanches Defaecation can be reached, but be only harmful to the health again with folium sennae defaecation, so three taste medicinal materials are used in combination for the invention, reduction kind It rushes down the dose of leaf, reduces the efficacy of a drug, but be aided with Radix Angelicae Sinensis again and Herba Cistanches are moistened and just lead to intestines, allow to smooth defaecation and reduce again Damage to body, while again due to Chinese angelica blood supplementing, the vim and vigour that folium sennae takes away again are supplemented, are made by Herba Cistanches tonifying Qi It obtains and the damage of body is minimized, and have the effect got instant result;Folium sennae is real secret as mainly curing mainly, this to it is empty it is secret can not It plays a role, but due to joined Radix Angelicae Sinensis and Herba Cistanches in this product, and the dosage of folium sennae is reduced, so that this tea bag It has certain effect similarly for treatment void is secret, alleviation can be haved the function that slight illness, and side effect will not be generated, to trouble Person goes correctly to select medicine more times.
In production method, S3 can avoid the occurrence of unqualified or other sick hidden danger with infection medicinal materials;In S4, Radix Angelicae Sinensis Clear cream is used with Herba Cistanches, is in order to preferably be mixed with cassia angustifolia leaf coarse powder, as the clear cream preparation side of its Radix Angelicae Sinensis and Herba Cistanches Method is well-known technique, and details are not described herein again;Moisture is controlled when dry 10% hereinafter, be in order to when drug granule makes, It will not be bonded between grain, cause to increase and measure, and can also be improved the storage time of drug;Horizontal sealing temperature and longitudinal sealing temperature are It can make to encapsulate strict optimum temperature again in the case where not influencing internal drug.
This product is bag tea agent, and content is yellowish green coloured particles;Mildly bitter flavor.This product cures mainly, promoting of purging heat, relax bowel and defecation. For constipation, abdominal distension and senility habitual constipation caused by heat knot.
Usage and dosage: boiled water is taken after being infused in hot water or decoction, one time 2.5 grams, add 200 milliliters of hot-water soaks 10 minutes, once drink off;10 is small after clothes When non-defecation person, method as above impregnate again takes it is primary, to lead to for degree.
Use taboo: pregnant woman's disabling.
Points for attention: 1. diet are preferably light, quit smoking, wine and pungent, raw and cold, greasy food.
2. nourishing Chinese medicine should not be taken simultaneously in duration of medication.
3. having hypertension, heart disease, diabetes, hepatopathy, nephrosis chronic diseases serious person that should take in the case where doctor instructs.
4. this product should not be taken for a long time, 2 symptoms of taking medicine are not alleviated, should remove hospital admission.
5. strictly taking by usage and dosage, children, elderly and infirm should take in the case where doctor instructs.
6. pair this product allergy sufferers disable, allergic constitution person is used with caution.
7. this product character is forbidden to use when changing.
8. children must use under adult's monitoring.
9. this product is please placed on the place that children cannot contact.
10. other drugs are such as used, using asking Ref Dr or pharmacist before this product.
Below in conjunction with the experimental example in the present invention, the technical solution in the present invention is clearly and completely described.It is aobvious So, described embodiments are only a part of the embodiments of the present invention, instead of all the embodiments.Based on the reality in the present invention Example is applied, every other embodiment obtained by those of ordinary skill in the art without making creative efforts all belongs to In the scope of protection of the invention.
Experimental example:
Comparative example 1:
By weight, the raw material of the Chinese medicine composition of constipation is treated are as follows: 6 parts of folium sennae, 1 part of Radix Angelicae Sinensis, 1 part of Herba Cistanches, By appealing production method, it is prepared into tea bag.
Comparative example 2:
By weight, the raw material of the Chinese medicine composition of constipation is treated are as follows: 5 parts of folium sennae, 2 parts of Radix Angelicae Sinensis, 1 part of Herba Cistanches, By appealing production method, it is prepared into tea bag.
Comparative example 3:
By weight, the raw material of the Chinese medicine composition of constipation is treated are as follows: 7 parts of folium sennae, 1 part of Radix Angelicae Sinensis, 0 part of Herba Cistanches, By appealing production method, it is prepared into tea bag.
Comparative example 4:
By weight, the raw material of the Chinese medicine composition of constipation is treated are as follows: 5 parts of folium sennae, 1 part of Radix Angelicae Sinensis, 2 parts of Herba Cistanches, By appealing production method, it is prepared into tea bag.
Comparative example 5:
By weight, the raw material of the Chinese medicine composition of constipation is treated are as follows: 7 parts of folium sennae, 0 part of Radix Angelicae Sinensis, 1 part of Herba Cistanches, By appealing production method, it is prepared into tea bag.
Experiment is implemented, and measures to defecation time, stool interval, feces volume and active degree;
Take kind male white mouse 60, cleaning grade (II grades) Kunming, weight is 18~22g, be randomly divided into blank control group, 1 experimental group of comparative example, 2 experimental group of comparative example, 5 experimental group of 3 experimental group of comparative example, 4 experimental group of comparative example and comparative example, every group 10 Only.
Groups of animals fasting 16h (drinking-water unlimited), gives tested material using administration by gavage, respectively to 1 experimental group of comparative example, 2 experimental group of comparative example, 3 experimental group of comparative example, 4 experimental group of comparative example and 5 experimental group of comparative example fill the pharmacy solution of lower same components, The lower distilled water with pharmacy solution same components is filled to blank control group again, observes and records every small mouse's head grain row's melena time, 6h Excrement is dried at 100 DEG C to constant weight, calculates excrement water content, and observe active degree by interior defecation number and stool weight, The result is shown in following tables.
Come as can be seen from the above table, from the point of view of blank control group and other group comparisons, this product has significant treatment constipation Effect;By 1 experimental group of comparative example, 2 experimental group of comparative example, 5 experimental group of 3 experimental group of comparative example, 4 experimental group of comparative example and comparative example Data from the point of view of, the amount of main folium sennae is bigger, and defecation effect is better, but same, the amount of folium sennae is excessive and Radix Angelicae Sinensis or When Herba Cistanches lack, it is easy to happen the too quickly situation of medication, so the optimal formula scheme of this product is comparative example 1.

Claims (6)

1. a kind of for treating the tea bag of habitual constipation, which is characterized in that he extracts preparation by the bulk pharmaceutical chemicals of following deal It obtains:
6-30 parts of Senna leaf, 1-5 parts of Radix Angelicae Sinensis, 1-5 parts of Herba Cistanches.
2. according to claim 1 a kind of for treating the tea bag of habitual constipation, which is characterized in that it by dividing as follows The bulk pharmaceutical chemicals extraction of amount is prepared: 6 parts of Senna leaf, 1 part of Radix Angelicae Sinensis, 1 part of Herba Cistanches.
3. a kind of production method for treating the tea bag of habitual constipation is suitable for a kind of use as described in claim 1 In the tea bag for the treatment of habitual constipation, which comprises the following steps:
S1: it by folium sennae (medicine materical crude slice), sets in p-type coarse-cracking machine and crushes;
S2: smashed coarse powder is placed in screening machine, is screened into the medicinal powder of 20-60 mesh;
S3: medicinal powder being set in clean container, is examined microbial limit, is put in storage after the assay was approved spare;
S4: qualified cassia angustifolia leaf coarse powder, Radix Angelicae Sinensis, Herba Cistanches clear cream will be examined, respectively precise;
S5: load weighted cassia angustifolia leaf coarse powder is set in trough type mixing machine, and dry-mixed 10 minutes;
S6: Radix Angelicae Sinensis, Herba Cistanches clear cream are uniformly added into, and are stirred 10 minutes;
S7: mixed cream powder mixture is laid in stainless steel screen tray, is placed and drying in baking oven;
S8: crossing 14 meshes through oscillating granulator whole grain for dried cream powder mixture, sets and mixes 20 points in multinomial mixing machine It is to be tested to be sent into intermediate station after mixing for clock;
S9: tea bag after the assay was approved is dispensed with tea bag racking machine;
S10: every bag 2.5g, tea filter paper used, Key works Drug packing polyester aluminized complex film should meet inner packaging material specification mark Standard, the loading amount of monitoring in every 10 minutes;
S11: the tea bag dispensed is sent into intermediate station;
S12: by batch packaging directive to printed on capsule, middle box, big case lot number, the date of manufacture, valid until etc. information.
4. according to claim 3 a kind of for treating the tea bag production method of habitual constipation, which is characterized in that institute Be laid in the S7 stated in stainless screen tray, spread with a thickness of every disk 1.5-2.5cm.
5. according to claim 3 a kind of for treating the tea bag production method of habitual constipation, which is characterized in that institute In the S7 stated, it is placed in drying in baking oven, drying temperature is 50 DEG C -60 DEG C, and drying time is 120 minutes;And every 10 minutes An oven temperature is detected, by moisture control below 10.0%.
6. according to claim 3 a kind of for treating the tea bag production method of habitual constipation, which is characterized in that institute The racking machine of the S9 stated being previously mentioned, used packing temperature are as follows: horizontal sealing temperature: 130-155 DEG C;Longitudinal sealing temperature: 110-130 ℃。
CN201811438554.4A 2018-11-28 2018-11-28 A kind of tea bag and preparation method thereof for treating habitual constipation Pending CN109303801A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110228613A (en) * 2019-06-12 2019-09-13 贵州联盛药业有限公司 Broken wall medicine materical crude slice layered water flood well preparation method

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CN103520293A (en) * 2013-09-27 2014-01-22 甘肃扶正药业科技股份有限公司 Oral traditional Chinese medicine for improving and treating constipation

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Publication number Priority date Publication date Assignee Title
CN101732415A (en) * 2008-11-26 2010-06-16 北京亚东生物制药有限公司 Methods for controlling quality of Chinese medicinal composition preparation
CN103520293A (en) * 2013-09-27 2014-01-22 甘肃扶正药业科技股份有限公司 Oral traditional Chinese medicine for improving and treating constipation

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
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Application publication date: 20190205