CN109303710A - A kind of compact maintenance composition of novel skin, preparation and preparation method thereof - Google Patents
A kind of compact maintenance composition of novel skin, preparation and preparation method thereof Download PDFInfo
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- CN109303710A CN109303710A CN201811515102.1A CN201811515102A CN109303710A CN 109303710 A CN109303710 A CN 109303710A CN 201811515102 A CN201811515102 A CN 201811515102A CN 109303710 A CN109303710 A CN 109303710A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/68—Sphingolipids, e.g. ceramides, cerebrosides, gangliosides
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/342—Alcohols having more than seven atoms in an unbroken chain
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
- A61K8/345—Alcohols containing more than one hydroxy group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/40—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
- A61K8/44—Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/678—Tocopherol, i.e. vitamin E
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/735—Mucopolysaccharides, e.g. hyaluronic acid; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Abstract
The present invention relates to the technical field of cosmetics, the compact maintenance composition of especially a kind of novel skin, preparation and preparation method thereof, the compact maintenance composition of novel skin, the raw material including following weight percent: skin-rehabilitating agent 0.1%~5.0%；Skin-tightening agent 0.1%~7.0%；Preservative 0.1%~1.0%；Moisturizer 1.0%~10.0%；Water surplus.Phenomena such as compact maintenance composition of novel skin and the preparation being prepared are suitble to skin allergy, itch, furfur, redness caused by sensitive and cosmetics improper use, it solves and vast likes to be beautiful women in cosmetics use process, the puzzlement that phenomena of cutaneous irritation frequently generates, and the skin lesion problem bigger caused by patient using hormone therapy allergic skin inflammation, both it had been suitable for alleviation and prevention of the sensitive for allergic symptom, it is suitable for the allergic symptom due to caused by cosmetics improper use again, preparation method is simple, quick.
Description
Technical field
The present invention relates to the technical field of cosmetics, the compact maintenance composition of especially a kind of novel skin, preparation and its
Preparation method.
Background technique
What nowadays modern faced is not only life stress, and operating pressure is also increasing.Skin is to be covered on human body table
The maximum organ in face is aoxidized, the thorn of various tension-causing factors such as dry and ultraviolet light due to directly contacting with external environment
Swash, therefore is highly susceptible to damage.Meanwhile and because of the influence of the internal factors such as age, diet and living habit, lead to skin
The decline of function and hereditary grotesque, so that skin is more easier aging.Since skin is the outermost in human body, a mesh
The beauty of human body is demonstrated by with being clear, so anti-aging cosmetics become one of the product of vast female consumer urgent need.
Anti-aging cosmetics have accounted for 50% of Cosmetic Market or more, the main factor of skin aging first is that skin is long
Phase skin photoage caused by by ultraviolet radioactive.The light aging of skin is since free radical increases in skin, and free radical can damage
Biomembrane promotes elastin fibers increase and amorphization and collagen fabric to substantially reduce and grape ammonia glycan
The skin ageing phenomenons such as increase.Many women do not stint the urgent cause needle in beauty parlor for firm skin, anti-aging etc., but skin
The situation of skin but go fromes bad to worse, or even generates insoluble severe allergy phenomenon, it is therefore desirable to develop one kind safely and effectively
Firm skin anti-aging cosmetics.
Summary of the invention
The technical problem to be solved by the present invention is being provided a kind of new to solve the problems, such as above-mentioned background technique
Type skin-tightening maintenance composition, preparation and preparation method thereof.
The technical solution adopted by the present invention to solve the technical problems is: a kind of compact maintenance composition of novel skin, packet
Include the raw material of following weight percent:
Skin-rehabilitating agent 0.1%~5.0%
Skin-tightening agent 0.1%~7.0%
Preservative 0.1%~1.0%
Moisturizer 1.0%~10.0%
Water surplus.
Further specifically, in above-mentioned technical proposal, the skin-rehabilitating agent is Cer NP, Cer AP
II, the combination of Cer EOS, cholesterine, phytosphingosine, lauroyl dilactic acid sodium, carbomer and xanthan gum.
Wherein, ceramide is also known as sphingolipid, is to be present in lipoid between the outermost corneocyte of human skin
The main composition (> 50%) of body, playing prevents moisture from distributing and having to outside stimulus the important function of safeguard function, undertakes
Protection skin and moisten, moisture-keeping functions, many research reports are pointed out, can be produced by using the external plaster class containing ceramide
Product achieve the purpose that prevent anaphylaxis dermatosis and inhibit the effect of melanin foxiness.
Cholesterine also known as cholesterol, cholesterol are the indispensable important substances of institute of animal tissue cell, it is not only involved in
Cell membrane is formed, and is synthetic bile acid, the raw material of vitamin D and steroid hormone.Cholesterol can also be converted into through metabolism
Bile acid, steroid hormone, 7-DHC, and 7-DHC will be changed into vitamin through ultraviolet light irradiation
D3。
Phytosphingosine (PHYTOSPHINGOSINE) belongs to skin self component, is composition keratoderma water lock barrier
Lipid sources, be maintain skin natural protection function key substance, the substance natural no stimulation, be wide spectrum dermatology
Active particles and natural inflammation modulators can mitigate stimulation of the various inflammatory factors to skin.
Further specifically, in above-mentioned technical proposal, the skin-tightening agent is water, lysine, serine, color ammonia
The combination of acid, arginine, aspartic acid, cysteine, glycerol, 1,2- hexylene glycol and Sensiva SC50.
Wherein, it is biosimulation conotoxin victory peptide that skin-tightening agent, which is cone shell creotoxin, by sequence, artificial synthesized vertical
Body peptide, special 3D structure.Cone shell creotoxin provides the myorelaxant effects of very robber, provides crease-resistant effect instant rapidly
Fruit.Cone shell creotoxin provides effective loosening all muscles but not exclusively stiff paralysis, retains the conduction of 5% neuromuscular electric current of muscle, institute
To provide natural return of spring effect.
Conotoxin is the victory peptide that height folds, and is strongly penetrated, high stability, and reaching for muscle for Objective is loosened
Effect.Cone shell creotoxin passes through the blocking voltage dependence sodium-ion channel of Objective, blocks the channel NAv1.4 especially to hinder
The nervimuscular electric current that breaks conducts, and reaches and effectively relaxs one's muscles, and moment desalinates the effect of wrinkle.
Further specifically, in above-mentioned technical proposal, the preservative is Phenoxyethanol, Sensiva SC50, hydroxyl
The combination of one or more of benzene methyl, Nipasol and decoyl hydroximic acid.
Further specifically, in above-mentioned technical proposal, the moisturizer is glycerol, propylene glycol, butanediol, 1,3- third
The combination of one or more of glycol, 1,2- hexylene glycol, glycine betaine and Sodium Hyaluronate.
A kind of preparation containing the compact maintenance composition of novel skin, including raw material have A phase, B phase, C phase, D phase, E phase and F
Phase；
The ingredient of the A phase has deionized water, Jojoba esters, EG, Depuffin and Sodium Hyaluronate；
The ingredient of the B phase has butanediol and DC345；
The ingredient of the C phase has BPN-tosoro 1600；
The ingredient of the D phase has glycerol and TIO；
The ingredient of the E phase has the thick ester of silk and AVC；
The ingredient of the F phase has liquid crystal emulsifier, freezes the age factor, vitamin E, bisabolol, A91 and 1,2- hexylene glycol.
A kind of preparation method of preparation, includes following steps:
Step 1: A group raw material is heated to 60 DEG C~70 DEG C, and is stirred to being completely dissolved, A phase is formed；
Step 2: B being added to after being heated with stirring to 80 DEG C~90 DEG C, is pumped into emulsion pot, high speed homogenization 1min~3min is opened
Cooling water temperature is down to 60 DEG C~70 DEG C and is added to D group raw material, stirs the simultaneously homogeneous 2min~4min of high speed；
Step 3: after mixed phase stirring is cooled to 40 DEG C~50 DEG C, C, E, F group raw material is added, stirs evenly, form ABCDEF
Mixed phase；
Step 4: ABCDEF mixed phase is cooled to 30 DEG C~40 DEG C, discharging obtains preparation.
The beneficial effects of the present invention are: a kind of compact maintenance composition of novel skin provided by the invention, preparation and its system
Preparation Method is based on biological principle, and for age, skin can follow the string and contraction of muscle dies down, and skin becomes pine
It relaxes, forms gauffer, because the permeability increase that Lymphatic Circulation weakens with capillary gathers water, Depuffin can white inhibition blood vessel
Low-moisture aggregation drops in permeability, and Depuffin can also inhibit the activity of ACE enzyme, to be changed by antihypertensive function
Kind blood circulation；It has the active effect that the compact maintenance composition of novel skin can be made into creme or aqua, is applied directly to suffer from
Place, compared to oral or injectivity antiallergic drug, the effect that has no toxic side effect is good, easy to use, and there is very strong antiallergic to repair
Multiple, anti-inflammatory convergence and other effects, can make skin tender, smooth, moist, easy to use, reach moisturizing, repair impaired skin
The purpose of skin；The compact maintenance composition of novel skin and the preparation being prepared are suitble to sensitive and cosmetics using not
When caused skin allergy, itch, furfur, the redness phenomena such as, solve it is vast like to be beautiful women in cosmetics use process, skin
The puzzlement that skin allergic phenomena frequently generates, and the skin bigger caused by patient using hormone therapy allergic skin inflammation
Damage problem had not only been suitable for alleviation and prevention of the sensitive for allergic symptom, but also was suitable for since cosmetics are not using
When caused allergic symptom, preparation method is simple, quick.
Specific embodiment
In order to which the technical problems, technical solutions and beneficial effects solved by the present invention is more clearly understood, below in conjunction with
Embodiment, the present invention will be described in further detail.It should be appreciated that specific embodiment described herein is only used to explain
The present invention is not intended to limit the present invention.
A kind of compact maintenance composition of novel skin, the raw material including following weight percent:
Skin-rehabilitating agent 0.1%~5.0%
Skin-tightening agent 0.1%~7.0%
Preservative 0.1%~1.0%
Moisturizer 1.0%~10.0%
Water surplus.
Skin-rehabilitating agent is Cer NP, Cer AP II, Cer EOS, cholesterine, phytosphingosine, lauroyl
The combination of dilactic acid sodium, carbomer and xanthan gum.
Skin-tightening agent be water, lysine, serine, tryptophan, arginine, aspartic acid, cysteine, glycerol, 1,
The combination of 2- hexylene glycol and Sensiva SC50.
Preservative be one of Phenoxyethanol, Sensiva SC50, methyl hydroxybenzoate, Nipasol and decoyl hydroximic acid or
Two or more combinations.
Moisturizer is in glycerol, propylene glycol, butanediol, 1,3-PD, 1,2- hexylene glycol, glycine betaine and Sodium Hyaluronate
A combination of one or more.
A kind of preparation containing the compact maintenance composition of novel skin, including raw material have A phase, B phase, C phase, D phase, E phase and F
Phase；The ingredient of A phase has deionized water, Jojoba esters, EG, Depuffin and Sodium Hyaluronate；The ingredient of B phase have butanediol and
DC345；The ingredient of C phase has BPN-tosoro 1600；The ingredient of D phase has glycerol and TIO；The ingredient of E phase has the thick ester of silk and AVC；
The ingredient of F phase has liquid crystal emulsifier, freezes the age factor, vitamin E, bisabolol, A91 and 1,2- hexylene glycol.
A kind of preparation method of preparation, includes following steps:
Step 1: A group raw material is heated to 60 DEG C~70 DEG C, and is stirred to being completely dissolved, A phase is formed；
Step 2: B being added to after being heated with stirring to 80 DEG C~90 DEG C, is pumped into emulsion pot, high speed homogenization 1min~3min is opened
Cooling water temperature is down to 60 DEG C~70 DEG C and is added to D group raw material, stirs the simultaneously homogeneous 2min~4min of high speed；
Step 3: after mixed phase stirring is cooled to 40 DEG C~50 DEG C, C, E, F group raw material is added, stirs evenly, form ABCDEF
Mixed phase；
Step 4: ABCDEF mixed phase is cooled to 30 DEG C~40 DEG C, discharging obtains preparation.
All skin-rehabilitating agents are the SK-INFLUX ceramides of German Ying Chuan company, and skin-tightening agent is Shenzhen dimension
The Depuffin and the jelly age factor of fine jade company.
Embodiment 1
Preparation containing the compact maintenance composition of novel skin is that skin-tightening repairs essence lotion, and wherein skin-tightening repairs essence
Water the preparation method is as follows:
The xanthan gum of the glycerol of 5g, the butanediol of 8g, the glycine betaine of 2g and 0.3g are mixed, add deionized water to 100g, heating
To 85 DEG C, keep the temperature 30 minutes, homogeneous 3 minutes, be cooled to 45 DEG C, by the Depuffin of SK-INFLUX, 2g of 2g and freeze age because
Son, suitable preservative are added, stir evenly.
Embodiment 2
Preparation containing the compact maintenance composition of novel skin is skin repair essence, wherein the preparation method of skin repair essence
It is as follows:
The U21 of the glycerol of 5g, the butanediol of 8g, the glycine betaine of 2g and 0.3g are mixed, adds deionized water to 100g, is warming up to 85
DEG C, 30 minutes are kept the temperature, homogeneous 3 minutes, is cooled to 45 DEG C, by the Depuffin of SK-INFLUX, 2g of 3g and freezes the age factor,
The potassium hydroxide of 0.2g, suitable preservative are added, stir evenly.
Embodiment 3
Preparation containing the compact maintenance composition of novel skin is skin repair lotion, wherein the preparation method of skin repair lotion
It is as follows:
The U21 of the glycerol of 5g, the butanediol of 8g, the glycine betaine of 2g and 0.3g are mixed, adds deionized water to 100g, is warming up to 85
DEG C, component A is made；By the cetostearyl alcohol of 1g, the ethylhexyl palmitate of 3g, 2.0g dimethyl silicone polymer and 4g
DC345 is mixed and heated to 80 DEG C, obtains B component；A, B component are mixed homogeneous a few minutes to emulsifying completely, are cooled to 45 DEG C, it will
The Depuffin and the jelly age factor of SK-INFLUX, 2g of 3g, the potassium hydroxide of 0.2g, suitable preservative and essence are added, stir
It mixes uniformly.
Embodiment 4
Preparation containing the compact maintenance composition of novel skin be cream, wherein cream the preparation method is as follows:
The U21 of the glycerol of 5g, the butanediol of 8g, the glycine betaine of 2g and 0.3g are mixed, adds deionized water to 100g, is warming up to 85
DEG C, component A is made；By the cetostearyl alcohol of 1g, the ethylhexyl palmitate of 3g, the dimethyl silicone polymer of 2.0g, 4g
The Jojoba esters of DC345,2g and the shea butter of 2g are mixed and heated to 80 DEG C, obtain B component；A, B component are mixed homogeneous
A few minutes to complete emulsification, are cooled to 45 DEG C, by the Depuffin of SK-INFLUX, 2g of 3g and freeze the age factor, the hydrogen of 0.2g
Potassium oxide, suitable preservative and essence are added, and stir evenly.
To show that the present invention has beneficial effect, the present invention passes through observation and the record of 80 person on probations, and data are such as
Under:
One, 80 40~55 years old volunteers are randomly divided into 4 test groups, respectively I group, II group, III group and
IV group.I group is divided into I1 group and I2 group, and I1 group uses the aqua of embodiment 1, and I2 group uses the aqua for being free of effective component.II group
It is divided into II1 group and II2 group, II1 group uses the essence agent of embodiment 2, and II2 group uses the essence agent for being free of effective component.
III group is divided into III1 group and III2 group, and III1 group uses the emulsion agent of embodiment 3, III2 group using be free of effectively at
The emulsion agent divided.IV group is divided into IV1 group and IV2 group, and IV1 group uses the cream of embodiment 4, and IV2 group use is free of
The cream of effective component.Effective component refers to SK-INFLUX ceramide, Depuffin and freezes the age factor.
Two, application method: I group and II group take appropriate product in the centre of the palm, pat cheek until fully absorbing, sooner or later
It is each primary, it uses daily, it is continuous to smear two months；III group and IV group take appropriate product in the centre of the palm, and massage cheek is to complete
Until absorption, once in the morning and once at night, use daily, it is continuous to smear two months.
Three, effect judgment criteria:
Skin lifting, compact degree, desalination wrinkle test: taking photo under from skinanalysis apparatus, observes the depth variation of deep wrinkle
And shallow wrinkle the case where reducing.
The test of skin elasticity degree: from skinanalysis apparatus test data, the variation of each test data, every aspiration are recorded
Person tests 3 groups of data every time, takes trim mean value, and 10 volunteer's data of each group are average again.
Four, result:
The skin of I1 group, II1 group, III1 group, IV1 group: addition SK-INFLUX ceramide, Depuffin and jelly are used
The preparation of the age factor, skin have obvious skin lifting, compact, desalination wrinkle, increase skin elasticity degree effect.
The skin of I2 group, II2 group, III2 group, IV2 group: unused addition SK-INFLUX ceramide,
Depuffin and the preparation for freezing the age factor, skin have mild skin lifting, compact, desalination wrinkle, increase skin elasticity degree effect.
1 skin elasticity degree test result of table
| Time | I1 group | I2 group | II1 group | II2 group | III1 group | III2 group | IV1 group | IV2 group |
| Blank | 15 | 17 | 16 | 15 | 18 | 17 | 17 | 17 |
| 1st day | 17 | 17 | 18 | 17 | 22 | 19 | 24 | 22 |
| 2nd day | 18 | 18 | 20 | 18 | 25 | 20 | 26 | 23 |
| 4th day | 20 | 19 | 21 | 18 | 26 | 22 | 28 | 25 |
| 6th day | 22 | 19 | 23 | 19 | 28 | 25 | 29 | 25 |
| 8th day | 23 | 18 | 25 | 19 | 30 | 25 | 30 | 27 |
| 10th day | 25 | 19 | 25 | 20 | 32 | 27 | 33 | 28 |
| 15th day | 27 | 19 | 28 | 19 | 32 | 27 | 35 | 30 |
| 20th day | 29 | 23 | 30 | 22 | 35 | 29 | 37 | 32 |
| 25th day | 30 | 23 | 30 | 23 | 35 | 30 | 37 | 32 |
| 30th day | 32 | 22 | 32 | 22 | 38 | 31 | 38 | 35 |
| 35th day | 34 | 23 | 33 | 23 | 40 | 33 | 42 | 35 |
| 40th day | 36 | 22 | 35 | 23 | 40 | 33 | 43 | 36 |
| 45th day | 36 | 23 | 36 | 24 | 42 | 35 | 45 | 38 |
| 50th day | 40 | 25 | 39 | 23 | 42 | 35 | 45 | 38 |
| 55th day | 40 | 25 | 41 | 24 | 43 | 38 | 47 | 40 |
| 60th day | 40 | 25 | 41 | 24 | 43 | 38 | 48 | 41 |
From above-mentioned experiment it can be concluded that
Add effect of the product of the present composition in terms of skin lifting, compact, desalination wrinkle, increase skin elasticity degree all
It is better than blank control group.In various dosage forms, the effect of cream is the most obvious, is secondly emulsion agent, essence agent, aqua.In sky
Bai Zuzhong, water and essence have moisturizer, if used daily, moisture of skin has increase, and the elasticity of skin also has slight increasing
Add；And not only have moisturizer in lotion and cream, there are also some greases, the effect of grease will moisturize the skin and in skin table
Face formed a tunic, so that moisture is not volatilized easily, thus using lotion and cream skin elasticity degree increase can than aqua with
Essence it is big.
It is above-described, it is merely preferred embodiments of the present invention, but protection scope of the present invention is not limited to
This, anyone skilled in the art in the technical scope disclosed by the present invention, according to the technique and scheme of the present invention
And its inventive concept is subject to equivalent substitution or change, should be covered by the protection scope of the present invention.
Claims (7)
1. a kind of compact maintenance composition of novel skin, characterized in that the raw material including following weight percent:
Skin-rehabilitating agent 0.1%~5.0%
Skin-tightening agent 0.1%~7.0%
Preservative 0.1%~1.0%
Moisturizer 1.0%~10.0%
Water surplus.
2. a kind of compact maintenance composition of novel skin as described in claim 1, it is characterized in that: the skin-rehabilitating agent is
Cer NP, Cer AP II, Cer EOS, cholesterine, phytosphingosine, lauroyl dilactic acid sodium, carbomer and Huang
The combination of virgin rubber.
3. a kind of compact maintenance composition of novel skin as described in claim 1, it is characterized in that: the skin-tightening agent is
Water, lysine, serine, tryptophan, arginine, aspartic acid, cysteine, glycerol, 1,2- hexylene glycol and ethylhexyl are sweet
The combination of oil.
4. a kind of compact maintenance composition of novel skin as described in claim 1, it is characterized in that: the preservative is benzene oxygen
The combination of one or more of ethyl alcohol, Sensiva SC50, methyl hydroxybenzoate, Nipasol and decoyl hydroximic acid.
5. a kind of compact maintenance composition of novel skin as described in claim 1, it is characterized in that: the moisturizer is sweet
One or more of oil, propylene glycol, butanediol, 1,3-PD, 1,2- hexylene glycol, glycine betaine and Sodium Hyaluronate
Combination.
6. a kind of preparation containing the compact maintenance composition of novel skin as described in claim 1, characterized in that including raw material
There are A phase, B phase, C phase, D phase, E phase and F phase；
The ingredient of the A phase has deionized water, Jojoba esters, EG, Depuffin and Sodium Hyaluronate；
The ingredient of the B phase has butanediol and DC345；
The ingredient of the C phase has BPN-tosoro 1600；
The ingredient of the D phase has glycerol and TIO；
The ingredient of the E phase has the thick ester of silk and AVC；
The ingredient of the F phase has liquid crystal emulsifier, freezes the age factor, vitamin E, bisabolol, A91 and 1,2- hexylene glycol.
7. a kind of preparation method of preparation as claimed in claim 6, characterized in that include following steps:
Step 1: A group raw material is heated to 60 DEG C~70 DEG C, and is stirred to being completely dissolved, A phase is formed；
Step 2: B being added to after being heated with stirring to 80 DEG C~90 DEG C, is pumped into emulsion pot, high speed homogenization 1min~3min is opened
Cooling water temperature is down to 60 DEG C~70 DEG C and is added to D group raw material, stirs the simultaneously homogeneous 2min~4min of high speed；
Step 3: after mixed phase stirring is cooled to 40 DEG C~50 DEG C, C, E, F group raw material is added, stirs evenly, form ABCDEF
Mixed phase；
Step 4: ABCDEF mixed phase is cooled to 30 DEG C~40 DEG C, discharging obtains preparation.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811515102.1A CN109303710A (en) | 2018-12-12 | 2018-12-12 | A kind of compact maintenance composition of novel skin, preparation and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811515102.1A CN109303710A (en) | 2018-12-12 | 2018-12-12 | A kind of compact maintenance composition of novel skin, preparation and preparation method thereof |
Publications (1)
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| CN109303710A true CN109303710A (en) | 2019-02-05 |
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| CN201811515102.1A Pending CN109303710A (en) | 2018-12-12 | 2018-12-12 | A kind of compact maintenance composition of novel skin, preparation and preparation method thereof |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110251414A (en) * | 2019-07-19 | 2019-09-20 | 珠海海狮龙生物科技有限公司 | A kind of anti-wrinkle cream and preparation method thereof |
| CN110917055A (en) * | 2019-12-20 | 2020-03-27 | 浙江润和生物科技有限公司 | Oligopeptide repair essence and preparation process thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3156928B1 (en) * | 1999-12-21 | 2001-04-16 | カネボウ株式会社 | Skin tightening agents and cosmetics |
| CN105919827A (en) * | 2016-06-01 | 2016-09-07 | 北京希诺赛尔健康科技推广有限公司 | Skin care composition with moisturizing and wrinkle-resistant effects |
| CN107737041A (en) * | 2017-11-17 | 2018-02-27 | 珠海姗拉娜化妆品有限公司 | A kind of novel skin antiallergic maintenance composition, skin repair frost and preparation method thereof |
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2018
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3156928B1 (en) * | 1999-12-21 | 2001-04-16 | カネボウ株式会社 | Skin tightening agents and cosmetics |
| CN105919827A (en) * | 2016-06-01 | 2016-09-07 | 北京希诺赛尔健康科技推广有限公司 | Skin care composition with moisturizing and wrinkle-resistant effects |
| CN107737041A (en) * | 2017-11-17 | 2018-02-27 | 珠海姗拉娜化妆品有限公司 | A kind of novel skin antiallergic maintenance composition, skin repair frost and preparation method thereof |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110251414A (en) * | 2019-07-19 | 2019-09-20 | 珠海海狮龙生物科技有限公司 | A kind of anti-wrinkle cream and preparation method thereof |
| CN110917055A (en) * | 2019-12-20 | 2020-03-27 | 浙江润和生物科技有限公司 | Oligopeptide repair essence and preparation process thereof |
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