CN109288994A - A kind of hypolipemic ' Tongluowan ' prescription and its preparation process - Google Patents
A kind of hypolipemic ' Tongluowan ' prescription and its preparation process Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/482—Cassia, e.g. golden shower tree
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8994—Coix (Job's tears)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
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Abstract
A kind of hypolipemic ' Tongluowan ' prescription provided by the invention and its preparation process, using Radix Salviae Miltiorrhizae, American Ginseng, Poria cocos, Radix Notoginseng, semen coicis, hawthorn, Rhizoma Chuanxiong, Cassia pure Chinese medicine composition composition, be my section preventive treatment of disease center after a large amount of clinical practice from quasi- formula, cure mainly person in middle and old age and sub-health population, for preventing and treating plasma lipid profile exception, Chinese medical discrimination category qi depression to blood stasis, spleen deficiency phlegm coagulate card person, it can reduce blood lipid, improve patients with lipid's compliance rate, steady lipid-loweringing, and improve patient symptom, it is curative for effect, good security.
Description
Technical field
The present invention relates to Chinese medicine preparations, specifically, being a kind of Chinese medicine preparation with reducing lipid and dredging collaterals effect and its preparation
Technique.
Background technique
As social economy rapidly develops, lifestyle change, hyperlipidemia is serious to threaten the people's
Living safety, prevention and treatment dyslipidemia have become cardiovascular and cerebrovascular disease basis prevention in important link, a large amount of evidence-based medicine EBM and
Clinical research confirmation Lipid modulating is significant in cardiovascular disease prevention, athero- especially for coronary heart disease, artery
The firsts and seconds of hardening prevents, and Lipid modulating can improve the long-term prognosis of patient to some extent.But majority is used for
Treating and preventing the drug of hyperlipemia, that there is toxicities is more, and therapeutic effect is poor, takes the problems such as inconvenience.
Currently, the control measure of hyperlipidemia is broadly divided into non-drug and drug measure, non-drug therapy measure: including drink
Food adjusts and the adjusting (including motion exercise and smoking cessation) of other life styles, for preventing Hyperlipemia and hyperlipidemia
The basis for the treatment of；Drug therapy measure, using HMG-CoA reductase inhibitor (Statins) or sour placed separately dose or shellfish butyric acid class
Or the drugs such as niacin class or acipimox, however, some drugs treatment is easy to appear gastrointestinal system, nervous system and skin etc.
Adverse reaction.
Summary of the invention
For the status and trend of the prior art, the purpose of the present invention is to provide a kind of hypolipemic ' Tongluowan ' prescription and its systems
Standby technique, which is that center is preventiveed treatment of disease in a large amount of clinical practices in my section, under the guidance of differentiation of tcm principle, can be dropped
Low blood lipid improves patients with lipid's compliance rate, steady lipid-loweringing, and improves patient symptom, curative for effect, good security
One effective herbal treatment side.
A kind of hypolipemic ' Tongluowan ' prescription of the invention, it is characterised in that: the drug crude drug includes: Radix Salviae Miltiorrhizae, American Ginseng, Fu
Siberian cocklebur, Radix Notoginseng, semen coicis, hawthorn, Rhizoma Chuanxiong, cassia seed；It the ratio of each component is: Radix Salviae Miltiorrhizae 40g-200g, American Ginseng 10g-80g, Fu
Siberian cocklebur 40-200g, Radix Notoginseng 40-80g, semen coicis 40-200g, hawthorn 40-200g, Rhizoma Chuanxiong 10-80g, cassia seed 40-200g.
Further, the hypolipemic ' Tongluowan ' prescription, the optimum proportioning of each component are as follows: Radix Salviae Miltiorrhizae 158g, American Ginseng
52.5g, Poria cocos 158g, Radix Notoginseng 105g, semen coicis 158g, hawthorn 158g, Rhizoma Chuanxiong 52.5g, cassia seed 158g.
Reducing lipid and dredging collaterals side is made of Radix Salviae Miltiorrhizae, American Ginseng, Typhonium flagelliforme (Lodd.) Blume, Rhizoma Chuanxiong, Poria cocos, semen coicis, hawthorn, cassia seed.Radix Salviae Miltiorrhizae,
Bitter, cold nature, converge to heart and liver channels.Effect: promoting blood circulation, inducing meastruation to relieve menalgia, relieving restlessness and restlessness, cool blood to disappear carbuncle.Shennong's Herbal:
Trusted subordinate's perverse trend is controlled, borborygmus is faint such as to leak water, and fever and chills accumulation breaks disease and removes lump in the abdomen, only dysphoria, QI invigorating.Compendium of Material Medica: the red taste of Radix Salviae Miltiorrhizae color
Hardship, gas is flat and drops, the yang aspect of yin.Start with it is few yin, JUE YIN meridian.The heart and envelope blood system medicine.Jing-Yue Complete Works: mildly bitter flavor, micro-
Sweet, micro-puckery, slightly cool in nature are nontoxic.Anti-black false hellebore.Energy nourshing blood and promoting blood circulation, raw new blood, row place blood, therefore the peaceful tire of energy, fall stillborn foetus；Metrorrhagia band
Under can stop, passages through which vital energy circulates is irregular adjustable.The medicine of this heart spleen liver kidney blood system, thus also can yin-nourishing sedate, QI invigorating solution is tired, treat eye and ache foot numbness,
Easing joint movement and malignant sore scabies, cute conjunctivitis erysipelas, Apocenosis pain relieving, myogenic of putting on flesh.It can be seen that Radix Salviae Miltiorrhizae is blood system key medicine, it can promoting blood circulation
Stasis of blood energy blood-nourishing again, no matter actual situation can all use it.American Ginseng, sweet in flavor, slight bitter is cool in nature, return heart, lung, kidney channel.Effect: boosting qi and nourishing yin,
Clearing heat and promoting fluid." Records of Tradition Chinese and Western Medicine in Combination ": sweet and slightly bitter taste, it is cool in nature.Gas point, and energy help blood system can be subsidized, for its is cool in nature and mends,
All ginsengs to be used, all can be with this instead of without the temperature compensation person by ginseng.American Ginseng QI invigorating righting is to effect a permanent cure, in the Radix Salviae Miltiorrhizae altogether side of being
Monarch drug in a prescription.Typhonium flagelliforme (Lodd.) Blume, sweet in flavor, slight bitter is warm-natured, returns liver, stomach meridian.Effect: dissipating stasis and stanching bleeding, detumescence ding-tong.Jing-Yue Complete Works: gas sweet in flavor
Temperature is bright, negative blood system of fainting the medicine of sun, therefore kind styptic powder blood analgesic therapy.Typhonium flagelliforme (Lodd.) Blume can help Radix Salviae Miltiorrhizae activating microcirculation and removing stasis medicinal and Xu-tonic
The benefits of.Rhizoma Chuanxiong, acrid flavour is warm-natured, returns liver, gallbladder, pericardium channel.Effect: blood-activating and qi-promoting, wind-expelling pain-stopping, to control all pains of qi depression to blood stasis
Key medicine, then blood, this two taste help the function of Radix Salviae Miltiorrhizae activating microcirculation and removing stasis medicinal to gas row altogether, be side in ministerial drug.Poria cocos, it is sweet in flavor, light, it is mild-natured, return
The heart, lung, spleen, kidney channel.Effect: clearing damp and promoting diuresis, invigorating the spleen, calming heart.Semen coicis, sweet in flavor, light, cool in nature, returns spleen, stomach, lung channel.Effect:
Clearing damp and promoting diuresis, invigorating the spleen to arrest diarrhea, eliminating impediment, apocenosis, detoxicating and resolving a mass.This two taste, can invigorating the spleen, prevent the source of phlegm wet generation；It again can be straight
Clearing damp and promoting diuresis is connect, is adjutant in side.Hawthorn, sour, sweet, slightly warm in nature, returns spleen, stomach, Liver Channel.Effect: food digesting stomach fortifying, promoting the circulation of qi dissipate
The stasis of blood changes turbid lipid-loweringing."Herbal preparation": rushing down stagnant gas, and disperse accumulation dissipates the stasis of blood, resolving sputum.Cassia seed, sweet in flavor, bitter, salty, cold nature return liver, big
Intestines warp.Effect: clearing liver and improving vision, relax bowel and defecation.This two taste, modern pharmacology research clearly have reducing blood lipid, antiatherosclerosis
Effect, be also adjutant.Full side gather altogether activating microcirculation and removing stasis medicinal, invigorating the spleen excreting dampness, reducing lipid and dredging collaterals function.
The major functions: person in middle and old age and sub-health population, for preventing and treating plasma lipid profile exception, Chinese medical discrimination category qi depression to blood stasis, spleen deficiency phlegm
Solidifying card person.
For the hypolipemic ' Tongluowan ', the present invention also provides a kind of preparation process of hypolipemic ' Tongluowan ' prescription, the drops
The preparation process of rouge 'Tongluowan ' specifically includes that
Step 1: drug crude drug being crushed, 500 mesh is crossed, obtains fine powder；
Step 2: crossing 500 meshes；
Step 3: fine powder is uniformly mixed；
Step 4: with the modeling preparation method water-bindered pill: drug and auxiliary material mix → gob → pill item → segmentation processed and rub with the hands circle →
Drying → quality inspection → packaging；
Step 5: being placed in insulating box dry, 80 DEG C of dryings are advisable for 8~10 hours, water-bindered pill moisture, leach the time limit and need to meet
Regulation.
The beneficial effects of the present invention are: person in middle and old age and sub-health population are cured mainly, for preventing and treating plasma lipid profile exception, Chinese medical discrimination
Belong to the solidifying card person of qi depression to blood stasis, spleen deficiency phlegm, can reduce blood lipid, improves patients with lipid's compliance rate, steady lipid-loweringing, and change
Kind patient symptom, curative for effect, good security.
Specific embodiment
Embodiment 1:
A kind of hypolipemic ' Tongluowan ' prescription drug composition: Radix Salviae Miltiorrhizae 158g, American Ginseng 52.5g, Poria cocos 158g, Radix Notoginseng 105g, the heart of a lotus seed
Seed of jog's tears 158g, hawthorn 158g, Rhizoma Chuanxiong 52.5g, cassia seed 158g.
The preparation process for consolidating herbal paste of relievining asthma specifically includes that
Step 1: drug crude drug being crushed, 500 mesh is crossed, obtains fine powder；
Step 2: crossing 500 meshes；
Step 3: fine powder is uniformly mixed；
Step 4: with the modeling preparation method water-bindered pill: drug and auxiliary material mix → gob → pill item → segmentation processed and rub with the hands circle →
Drying → quality inspection → packaging；
Step 5: being placed in insulating box dry, 80 DEG C of dryings are advisable for 8~10 hours, water-bindered pill moisture, leach the time limit and need to meet
Regulation.
Embodiment 2:
One kind being directed to person in middle and old age and sub-health population, for preventing and treating the hypolipemic ' Tongluowan ' of plasma lipid profile abnormality disease, magistral medicines
Object composition includes: Radix Salviae Miltiorrhizae 45g American Ginseng 15g Poria cocos 45g Radix Notoginseng 30g seed of jog's tears 45g Radix Notoginseng 30g seed of jog's tears 45g hawthorn 45g Rhizoma Chuanxiong 15g
Cassia seed 45g.
The preparation process of the hypolipemic ' Tongluowan ' specifically includes that
Step 1: drug crude drug being crushed, 500 mesh is crossed, obtains fine powder；
Step 2: crossing 500 meshes；
Step 3: fine powder is uniformly mixed；
Step 4: with the modeling preparation method water-bindered pill: drug and auxiliary material mix → gob → pill item → segmentation processed and rub with the hands circle →
Drying → quality inspection → packaging；
Step 5: being placed in insulating box dry, 80 DEG C of dryings are advisable for 8~10 hours, water-bindered pill moisture, leach the time limit and need to meet
Regulation.
The usage and dosage of the hypolipemic ' Tongluowan ' are as follows: warm boiled water, each 8-10g, 2 times a day.
Claims (3)
1. a kind of hypolipemic ' Tongluowan ' prescription, it is characterised in that: the hypolipemic ' Tongluowan ' drug crude drug include: Radix Salviae Miltiorrhizae, American Ginseng,
Poria cocos, Radix Notoginseng, semen coicis, hawthorn, Rhizoma Chuanxiong, Cassia；Each group distribution ratio share are as follows: Radix Salviae Miltiorrhizae 40g-200g, American Ginseng 10g-80g,
Poria cocos 40-200g, Radix Notoginseng 40-80g, semen coicis 40-200g, hawthorn 40-200g, Rhizoma Chuanxiong 10-80g, cassia seed 40-200g.
2. a kind of hypolipemic ' Tongluowan ' prescription according to claim 1, it is characterised in that: the hypolipemic ' Tongluowan ' prescription,
The optimum proportioning of each component are as follows: Radix Salviae Miltiorrhizae 158g, American Ginseng 52.5g, Poria cocos 158g, Radix Notoginseng 105g, semen coicis 158g, hawthorn
158g, Rhizoma Chuanxiong 52.5g, cassia seed 158g.
3. a kind of hypolipemic ' Tongluowan ', it is characterised in that: the preparation process specifically includes that
Step 1: drug crude drug being crushed, 500 mesh is crossed, obtains fine powder；
Step 2: crossing 500 meshes；
Step 3: fine powder is uniformly mixed；
Step 4: being mixed with the modeling preparation method water-bindered pill: drug and auxiliary material → gob → pill item → segmentation processed and stranding are justified → is dried
→ quality inspection → packaging；
Step 5: be placed in insulating box it is dry, 80 DEG C drying 8~10 hours.
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Cited By (2)
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| CN113144114A (en) * | 2021-04-29 | 2021-07-23 | 湖南中医药大学第一附属医院((中医临床研究所)) | Traditional Chinese medicine composition for reducing blood fat and preparation method thereof |
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| CN113144114A (en) * | 2021-04-29 | 2021-07-23 | 湖南中医药大学第一附属医院((中医临床研究所)) | Traditional Chinese medicine composition for reducing blood fat and preparation method thereof |
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Application publication date: 20190201 |