CN109276592A - A kind of Chinese medicine composition for treating acute lymphangitis - Google Patents
A kind of Chinese medicine composition for treating acute lymphangitis Download PDFInfo
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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Abstract
The present invention relates to technical field of traditional Chinese medicines, especially a kind of Chinese medicine composition for treating acute lymphangitis, by weight, it is made of by weight following raw materials: 50-70 portions of feverfews, 25-35 parts of campanulaceaes, 30-40 portions of Radix Glycyrrhizaes, 50-70 portions of dandelions, 20-30 portions of Radix Notoginseng, 20-30 parts of Poria cocos, 10-15 parts of radix bupleuri, 10-15 parts of pueraria lobatas, 10-15 parts of Cortex Magnoliae Officinalis, 6-10 parts of rhizoma atractylodis, 3-5 parts of dried orange peels, 3-5 portions of fructus hordei germinatus.Chinese medicine composition provided by the invention has clearing heat and detoxicating, carbuncle that disappears dissipating bind, clearing damp, antibacterial effect, and absorption of human body effect is good, has good curative effect to acute lymphangitis, without side-effects.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, the Chinese medicine composition of specifically a kind for the treatment of acute lymphangitis.
Background technique
Acute lymphangitis also known as red malignant boil, blood arrow malignant boil, acute superficial lymphangitis, spun gold sore, trace of blood sore, one kind of furunculosis are mainly in four limbs, because
There is thin red silk one, walks to alter rapidly upward, it is therefore named " acute lymphangitis ".Acute lymphangitis is referred to as " acute lymphangitis " in modern medicine,
For common clinical, frequently-occurring disease.Acute lymphangitis is since pathogenic bacteria are from skin wound or other infection focus (furuncle, carbuncle, ulcer, foots
Tinea and chronic eczema etc.) it invades, the lymph space through organizing enters in lymphatic vessel, causes lymphatic vessel inflammation;Its pathogenic bacteria is gold
Staphylococcus aureus and hemolytic streptococcus.The main pathogenesis of this disease is that internal cause fire toxin stagnates, and external cause acute pyogenic infection of hands and feet feels fire again
Heat toxin is evil, and intoxicating heresy flows through arteries and veins and secondary disease.
Currently, patient is more likely to treat using Chinese medicine since the side effect of acute lymphangitis treatment antibiotic is big, lead to city
Many Chinese materia medica preparations are gone out on.The support of the not no tcm theory of most of these Chinese materia medica preparations, only simple drug is accumulative,
Its clinical efficacy waits to evaluate;Or raw material are more precious, the price of drug is relatively high, is unable to popularity use.
Summary of the invention
In order to solve the above technical problems existing in the prior art, the present invention provides a kind of Chinese medicines for treating acute lymphangitis
Composition.The Chinese medicine that the present invention uses all be it is relatively common in life, raw material is cheap and is easy to get, preparation method letter
It is single.
A kind of Chinese medicine composition for treating acute lymphangitis, by weight, including following raw material: 50-70 parts of feverfews, 25-
35 parts of campanulaceaes, 30-40 portions of Radix Glycyrrhizaes, 50-70 portions of dandelions.
Preferably, the Chinese medicine composition of the treatment acute lymphangitis further includes by weight following raw material: 20-30 parts
Radix Notoginseng, 20-30 part Poria cocos, 10-15 parts of radix bupleuri, 10-15 parts of pueraria lobatas, 10-15 parts of Cortex Magnoliae Officinalis, 6-10 parts of rhizoma atractylodis, 3-5 parts of dried orange peels, 3-5
Part fructus hordei germinatus.
Preferably, the preparation method of the Chinese medicine composition of the treatment acute lymphangitis, including following procedure:
(1) chrysanthemum, campanulaceae, Radix Glycyrrhizae, dandelion are mixed, 6 times of water is added and decoct 4h or so, homogenate obtains slurries;
(2) Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata, Cortex Magnoliae Officinalis, rhizoma atractylodis, dried orange peel, fructus hordei germinatus are mixed, obtains mixture;By mixture
It is added to Steam by water bath 15-20min in steamer, opens pot cover, some edible wines is sprinkled with, covers pot cover, continues to steam 5-8min, it is off the pot,
It mashes;
(3) paste smash is taken, 10 times of 60% ethyl alcohol stirring is added and extracts 40-60min, filtering is recycled ethyl alcohol, obtained
Extracting solution;
(4) extracting solution is uniformly mixed with the slurries of step (1), is brewed into paste, then spray-dried, obtains Chinese medicine
Powder.
Preferably, the step (2), the dosage of edible wine are the 0.2-0.3% of mixture quality.
Preferably, the step (3), Extracting temperature are 50-60 DEG C.
Preferably, the tanning temperature is 40-50 DEG C.
Preferably, the traditional Chinese medicine powder be added pharmaceutically acceptable auxiliary material can be made into tablet, pill, capsule, granule,
Oral agents.
The beneficial effects of the present invention are: chrysanthemum, campanulaceae, Radix Glycyrrhizae, dandelion are applied in combination to be dissipated with the clearing heat and detoxicating, carbuncle that disappears
Knot, clearing damp, antibacterial effect can effectively solve and the internal cause fire toxin of acute lymphangitis caused to stagnate, and the gold for leading to acute lymphangitis
Staphylococcus aureus and hemolytic streptococcus have stronger inhibiting effect;Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata are applied in combination to have and be good for
Taste, liver-protective effect, caused taste are uncomfortable when Chinese medicine can be prevented edible, enhance the absorption function of human body;It is Cortex Magnoliae Officinalis, grey
Art, dried orange peel, fructus hordei germinatus, which are applied in combination, to be had the function of improving body absorbability, and people can be promoted by being added in the Chinese medicine composition
Absorption of the body to effective component in Chinese medicine enhances drug effect.There is Chinese medicine composition provided by the invention the clearing heat and detoxicating, carbuncle that disappears to dissipate
Knot, clearing damp, antibacterial effect, and absorption of human body effect is good, has good curative effect to acute lymphangitis, it is without side-effects.
Specific embodiment
It is limited below with reference to specific embodiment technical solution of the present invention is further, but claimed
Range is not only limited to made description.
1 powder of embodiment
Component: 50g feverfew, 25g campanulaceae, 30g Radix Glycyrrhizae, 50g dandelion, 20g Radix Notoginseng, 20g Poria cocos, 10g radix bupleuri, 10g
Pueraria lobata, 10g Cortex Magnoliae Officinalis, 6g rhizoma atractylodis, 3g parts of dried orange peels, 3g fructus hordei germinatus.
Preparation method, including following procedure:
(1) chrysanthemum, campanulaceae, Radix Glycyrrhizae, dandelion are mixed, 6 times of water is added and decoct 4h or so, homogenate obtains slurries;
(2) Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata, Cortex Magnoliae Officinalis, rhizoma atractylodis, dried orange peel, fructus hordei germinatus are mixed, obtains mixture;By mixture
It is added to Steam by water bath 15min in steamer, opens pot cover, some edible wines is sprinkled with, covers pot cover, is continued after steaming 6min, it is off the pot, it is pounded
Paste;Wherein, the dosage of edible wine is the 0.2% of mixture quality;
(3) paste smash is taken, 10 times of 60% ethyl alcohol is added and stirs extraction 40min at 50-60 DEG C, filters, recycling
Ethyl alcohol obtains extracting solution;
(4) extracting solution is uniformly mixed with the slurries of step (1), paste is brewed at 40-50 DEG C, then through spraying dry
It is dry, traditional Chinese medicine powder is obtained, is packed to get powder.
The application method of powder: it is oral, 3 times a day, each 5-6g.
2 pill of embodiment
Component: 55g feverfew, 28g campanulaceae, 36g Radix Glycyrrhizae, 56g dandelion, 24g Radix Notoginseng, 24g Poria cocos, 12g radix bupleuri, 12g
Pueraria lobata, 12g Cortex Magnoliae Officinalis, 6g rhizoma atractylodis, 3g dried orange peel, 3g fructus hordei germinatus.
Preparation method, including following procedure:
(1) chrysanthemum, campanulaceae, Radix Glycyrrhizae, dandelion are mixed, 6 times of water is added and decoct 4h or so, homogenate obtains slurries;
(2) Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata, Cortex Magnoliae Officinalis, rhizoma atractylodis, dried orange peel, fructus hordei germinatus are mixed, obtains mixture;By mixture
It is added to Steam by water bath 18min in steamer, opens pot cover, some edible wines is sprinkled with, covers pot cover, is continued after steaming 6min, it is off the pot, it is pounded
Paste;Wherein, the dosage of edible wine is the 0.24% of mixture quality;
(3) paste smash is taken, 10 times of 60% ethyl alcohol is added and stirs extraction 45min at 50-60 DEG C, filters, recycling
Ethyl alcohol obtains extracting solution;
(4) extracting solution is uniformly mixed with the slurries of step (1), paste is brewed at 40-50 DEG C, then through spraying dry
It is dry, obtain traditional Chinese medicine powder;
(5) it will be added in traditional Chinese medicine powder, stir while adding, after mixing, by every 10-12g's after the heating of chaste tree nectar
Pellet is made in weight, and packaging can be obtained pill;The dosage of the chaste tree nectar is 1.5 times of traditional Chinese medicine powder quality.
The application method of pill: it is oral, 3 times a day, 1-2 tablets each time.
3 tablet of embodiment
Component: 60g feverfew, 30g campanulaceae, 35g Radix Glycyrrhizae, 60g dandelion, 24g Radix Notoginseng, 26g Poria cocos, 12g radix bupleuri, 14g
Pueraria lobata, 12g Cortex Magnoliae Officinalis, 8g rhizoma atractylodis, 4g dried orange peel, 4g fructus hordei germinatus.
Preparation method, including following procedure:
(1) chrysanthemum, campanulaceae, Radix Glycyrrhizae, dandelion are mixed, 6 times of water is added and decoct 4h or so, homogenate obtains slurries;
(2) Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata, Cortex Magnoliae Officinalis, rhizoma atractylodis, dried orange peel, fructus hordei germinatus are mixed, obtains mixture;By mixture
It is added to Steam by water bath 18min or so in steamer, opens pot cover, some edible wines is sprinkled with, covers pot cover, is continued after steaming 8min, it is off the pot,
It mashes;Wherein, the dosage of edible wine is the 0.25% of mixture quality;
(3) paste smash is taken, 10 times of 60% ethyl alcohol is added and stirs extraction 45min at 50-60 DEG C, filters, recycling
Ethyl alcohol obtains extracting solution;
(4) extracting solution is uniformly mixed with the slurries of step (1), paste is brewed at 40-50 DEG C, then through spraying dry
It is dry, obtain traditional Chinese medicine powder;
(5) starch that its quality 50% is added into traditional Chinese medicine powder is uniformly mixed, and softwood is made with 10% starch slurry, by softwood
16 mesh Shai Zhi wet granulars are crossed, wet granular is dried in 40-60 DEG C, 16 mesh sieves of dry particl claim dry particl weight, addition
3% talcum powder of grain amount mixes, and is pressed into the piece of 0.3-0.4g, sterilizes, and packs to get tablet.
The application method of tablet: it is oral, 3 times a day, each 5-6 piece.
4 capsule of embodiment
Component: 70g feverfew, 35g campanulaceae, 40g Radix Glycyrrhizae, 70g dandelion, 30g Radix Notoginseng, 30g Poria cocos, 15g radix bupleuri, 15g
Pueraria lobata, 15g Cortex Magnoliae Officinalis, 10g rhizoma atractylodis, 5g dried orange peel, 5g fructus hordei germinatus.
Preparation method, including following procedure:
(1) chrysanthemum, campanulaceae, Radix Glycyrrhizae, dandelion are mixed, 6 times of water is added and decoct 4h or so, homogenate obtains slurries;
(2) Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata, Cortex Magnoliae Officinalis, rhizoma atractylodis, dried orange peel, fructus hordei germinatus are mixed, obtains mixture;By mixture
It is added to Steam by water bath 20min in steamer, opens pot cover, some edible wines is sprinkled with, covers pot cover, is continued after steaming 8min, it is off the pot, it is pounded
Paste;Wherein, the dosage of edible wine is the 0.3% of mixture quality;
(3) paste smash is taken, 10 times of 60% ethyl alcohol is added and stirs extraction 60min at 50-60 DEG C, filters, recycling
Ethyl alcohol obtains extracting solution;
(4) extracting solution is uniformly mixed with the slurries of step (1), paste is brewed at 40-50 DEG C, then through spraying dry
It is dry, obtain traditional Chinese medicine powder;
(5) starch that its quality 20% is added into traditional Chinese medicine powder is uniformly mixed, and softwood is made with 10% starch slurry, by softwood
20 mesh Shai Zhi wet granulars are crossed, wet granular are dried in 60-70 DEG C, dry particl is with 20 mesh sieves to get drug granule;It will obtain
Drug granule be filled into capsule by hand, every capsule shape fills 0.4-0.5g drug granule, and packaging obtains capsule.
The application method of capsule: it is oral, it is 3 times a day, 3-4 each.
5 granule of embodiment
Component: 70g feverfew, 30g campanulaceae, 40g Radix Glycyrrhizae, 60g dandelion, 25g Radix Notoginseng, 26g Poria cocos, 14g radix bupleuri, 15g
Pueraria lobata, 10g Cortex Magnoliae Officinalis, 6g rhizoma atractylodis, 3g dried orange peel, 3g fructus hordei germinatus.
Preparation method, including following procedure:
(1) chrysanthemum, campanulaceae, Radix Glycyrrhizae, dandelion are mixed, 6 times of water is added and decoct 4h or so, homogenate obtains slurries;
(2) Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata, Cortex Magnoliae Officinalis, rhizoma atractylodis, dried orange peel, fructus hordei germinatus are mixed, obtains mixture;By mixture
It is added to Steam by water bath 18min in steamer, opens pot cover, some edible wines is sprinkled with, covers pot cover, is continued after steaming 8min, it is off the pot, it is pounded
Paste;Wherein, the dosage of edible wine is the 0.3% of mixture quality;
(3) paste smash is taken, 10 times of 60% ethyl alcohol is added and stirs extraction 50min at 50-60 DEG C, filters, recycling
Ethyl alcohol obtains extracting solution;
(4) extracting solution is uniformly mixed with the slurries of step (1), paste is brewed at 40-50 DEG C, then through spraying dry
It is dry, obtain traditional Chinese medicine powder;
(5) add the sucrose of its quality 20% and 40% dextrin into traditional Chinese medicine powder, add water that softwood is made, cross 16 meshes, obtain
Wet granular is obtained, wet granular is dried in 60-80 DEG C, 16 mesh sieves of dry particl, packaging, i.e. acquisition granule.
The application method of granule: it is oral, 3 times a day, each 8-10g.
Embodiment 6
For embodiment 6 the difference from embodiment 1 is that not having Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata in raw material, remaining is identical.
Embodiment 7
For embodiment 7 the difference from embodiment 1 is that not having Cortex Magnoliae Officinalis, rhizoma atractylodis, dried orange peel, fructus hordei germinatus in raw material, remaining is identical.
Embodiment 8
Embodiment 8 is not the difference from embodiment 1 is that have Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata, Cortex Magnoliae Officinalis, rhizoma atractylodis, old in raw material
Skin, fructus hordei germinatus, remaining is identical.
1 clinical test of test example
Case selection: it chooses the patient for being diagnosed as acute lymphangitis through larger medical mechanism and amounts to 400, random point 8 groups, every group
50 people.
Treatment method: preparation made from 1-8 of the embodiment of the present invention is respectively adopted in 1-8 group, and disease is according to corresponding in embodiment
Application method take, 3 days as one therapeutic course after taking 2 course for the treatment of, counts its curative effect, as shown in table 1.
Diagnosis basis: (1) red silk appears first since hand, forearm or foot, calf, may extend to elbow, armpit or knee, stock seam
Place, the swelling and pain of Tong Shi You Xing core, swelling pain;Lesion depth person, skin is micro- red or not show silk, but accessible streak swelling and pressure
Bitterly.(2) generally there is aversion to cold, generate heat, headache, the symptoms such as rapid pulse.(3) distal limbs have suppurative lesion or trauma history.(4) blood is white
Total number of cells and neutrophil leucocyte increase.
Curative effect judgment criteria:
Cure: red silk moves back only, and constitutional symptom disappears;
Effective: red silk subsides, and constitutional symptom disappears, and there are rope item and tenderness;
Invalid: the red silk of suffering limb does not disappear, or even agglomeration is suppurated, or merges " septicemia ".
Table 1
Group | Case load | It cures | Effectively | Cure rate | It is efficient |
Embodiment 1 | 50 | 32 | 16 | 64% | 96% |
Implement sulphur 2 | 50 | 28 | 18 | 56% | 92% |
Embodiment 3 | 50 | 31 | 14 | 62% | 90% |
Embodiment 4 | 50 | 30 | 17 | 60% | 94% |
Embodiment 5 | 50 | 29 | 17 | 58% | 92% |
Embodiment 6 | 50 | 23 | 10 | 46% | 66% |
Embodiment 7 | 50 | 20 | 14 | 40% | 68% |
Embodiment 8 | 50 | 17 | 11 | 34% | 56% |
As seen from the table, Chinese medicine composition provided by the invention has a good effect acute lymphangitis, and cure rate is reachable
56% or more, it is efficient up to 90% or more;Cure rate, the effective percentage of embodiment 1 are apparently higher than embodiment 6-8, illustrate Radix Notoginseng,
Poria cocos, radix bupleuri, pueraria lobata, Cortex Magnoliae Officinalis, rhizoma atractylodis, dried orange peel, fructus hordei germinatus, which are added to Chinese medicine composition, can improve the curative effect of Chinese medicine.
2 typical case of test example
1, Zhang, male, 36 years old, Anshun of Guizhou people was diagnosed as acute lymphangitis, symptom in institute of traditional Chinese medicine of Guizhou Province in 2 months 2017 are as follows:
The left hand palm has scuffing, has a red silk along inboard arm, red, swollen, hot, pain has been walked from arm to trunk direction and altered armpit, armpit
Enlargement of lymph nodes tenderness has agglomeration, and skin-color is red, and fever, aversion to cold, nausea, headache, loss of appetite, whole body inability, yellow tongue fur;
Patient started to take powder prepared by the present invention in 11 days 2017, after a course for the treatment of (3 days as a treatment course) are used continuously, hair
Heat, aversion to cold, nausea, headache, loss of appetite, whole body inability, yellow tongue fur disappear substantially, continue to use a course for the treatment of, red silk moves back only, red
It is swollen to disappear, substantially fully recover.
2, it is sweet certain, female, 23 years old, Tongren district Guizhou Province people was diagnosed as acute lymphangitis, symptom in Guizhou Province People's Hospital in 2017 10
Are as follows: the naked place's wound suppuration of foot has a red silk along medial leg, stretches to knee armpit by foot is naked, enlargement pressure at knee armpit
Bitterly, there are extravasated blood, and fever, nausea, skelasthenia, moss thin yellow, soft and rapid pulse;Patient started to take this hair on January 10th, 2018
The tablet of bright preparation, after a course for the treatment of (3 days as a treatment course) are used continuously, extravasated blood subsides, and fever, nausea, skelasthenia, tongue fur are thin
Yellow, soft and rapid pulse disappears substantially, continues to use a course for the treatment of, red silk, swelling are moved back only, substantially fully recovered.
It is important to point out that, above embodiments and test example are only limitted to do further technical solution of the present invention herein
Elaboration and understanding, should not be understood as it is further to technical solution of the present invention limited, what those skilled in the art made
The innovation and creation of non-protruding essential characteristics and marked improvement still fall within protection category of the invention.
Claims (7)
1. a kind of Chinese medicine composition for treating acute lymphangitis, by weight, including following raw material: 50-70 parts of feverfews, 25-35
Part campanulaceae, 30-40 portions of Radix Glycyrrhizaes, 50-70 portions of dandelions.
2. as described in claim 1 treatment acute lymphangitis Chinese medicine composition, which is characterized in that by weight, further include with
Lower raw material: 20-30 portions of Radix Notoginseng, 20-30 parts of Poria cocos, 10-15 parts of radix bupleuri, 10-15 parts of pueraria lobatas, 10-15 parts of Cortex Magnoliae Officinalis, 6-10 parts it is grey
Art, 3-5 part dried orange peel, 3-5 portions of fructus hordei germinatus.
3. the preparation method of the Chinese medicine composition for the treatment of acute lymphangitis as claimed in claim 2, which is characterized in that including following mistake
Journey:
(1) chrysanthemum, campanulaceae, Radix Glycyrrhizae, dandelion are mixed, 6 times of water is added and decoct 4h or so, homogenate obtains slurries;
(2) Radix Notoginseng, Poria cocos, radix bupleuri, pueraria lobata, Cortex Magnoliae Officinalis, rhizoma atractylodis, dried orange peel, fructus hordei germinatus are mixed, obtains mixture;Mixture is added to
Steam by water bath 15-20min in steamer, opens pot cover, is sprinkled with some edible wines, covers pot cover, continues after steaming 6-8min, off the pot, smashes
At paste;
(3) paste smash is taken, 10 times of 60% ethyl alcohol stirring is added and extracts 40-60min, filtering is recycled ethyl alcohol, extracted
Liquid;
(4) extracting solution is uniformly mixed with the slurries of step (1), is brewed into paste, then spray-dried, obtains traditional Chinese medicine powder, it can
It is used directly as powder.
4. the preparation method of the Chinese medicine composition for the treatment of acute lymphangitis as claimed in claim 3, which is characterized in that the step
(2), the dosage of edible wine is the 0.2-0.3% of mixture quality.
5. the preparation method of the Chinese medicine composition for the treatment of acute lymphangitis as claimed in claim 3, which is characterized in that the step
(3), Extracting temperature is 50-60 DEG C.
6. the preparation method of the Chinese medicine composition for the treatment of acute lymphangitis as claimed in claim 3, which is characterized in that the tanning
Temperature is 40-50 DEG C.
7. the preparation method of the Chinese medicine composition for the treatment of acute lymphangitis as claimed in claim 3, which is characterized in that the Chinese medicine
Pharmaceutically acceptable auxiliary material, which is added, in powder can be made into tablet, pill, capsule, granule, oral agents.
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Application publication date: 20190129 |