CN109276470A - A kind of wind wind reparation ointment for baby - Google Patents
A kind of wind wind reparation ointment for baby Download PDFInfo
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- CN109276470A CN109276470A CN201811331452.2A CN201811331452A CN109276470A CN 109276470 A CN109276470 A CN 109276470A CN 201811331452 A CN201811331452 A CN 201811331452A CN 109276470 A CN109276470 A CN 109276470A
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- wind
- ointment
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- repairs
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/63—Steroids; Derivatives thereof
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/27—Zinc; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/005—Preparations for sensitive skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/40—Chemical, physico-chemical or functional or structural properties of particular ingredients
- A61K2800/59—Mixtures
- A61K2800/592—Mixtures of compounds complementing their respective functions
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- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
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- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Cosmetics (AREA)
Abstract
The present invention relates to articles for babies field, specifically a kind of wind wind for baby repairs ointment.It is characterized in that there is the material of following mass fraction to be made: stearyl alcohol glycyrrhetin 0.01~2.5%wt of acid esters, 0.5%~20%wt of zinc oxide, 0.5~3.5%wt of thickener, 1.5~25%wt of emollient, the vaseline of 0.1~2%wt of antioxidant and surplus；Preparation method includes the following steps: S1, and the vaseline mixed oxidization zinc and tapioca of 25~30%wt are put into dissolution kettle and dissolved for use；Remaining vaseline and thickener, stearyl alcohol glycyrrhetin acid esters, Garcinia indica seed rouge are put into emulsifying kettle and are emulsified for use by S2；S3 pours into dissolution kettle stand-by raw material in emulsifying kettle, deaeration, and keeping vacuum degree is 0.05~0.10Mpa；The emulsifying kettle for completing step S3 is cooled to 35~60 DEG C by S4, and pours into antioxidant stirring；S5 is stirred evenly, discharging.The present invention compared with the existing technology, can repair the skin of buttock of baby, it is ensured that baby avoids that diaper rash occurs.
Description
Technical field
The present invention relates to articles for babies field, specifically a kind of wind wind for baby repairs ointment.
Background technique
Diaper dermatitis is also known as diaper rash, is the contact scytitis occurred in the baby' diaper area of coverage, is mainly manifested in
The appearance of the erythema, erythema of diaper covering part.Epidemiological study the result shows that, the morbidity of diaper dermatitis in infant crowd
Rate is 7%~35%, wherein the disease incidence of diaper dermatitis is up to 17%~43% in hospital in the crowd of baby and children.Although this
Skin problem is relatively common in infant group, but due to the delay of the course of disease and and ask repeatedly, cause infant pain, cry
Noisy, poor sleep easily causes the intrusion of the pathogenic microorganisms such as bacterium and fungi if protecting not in time, causes to infect, seriously
Infant is influenced normally to grow up and live.Very big stress is caused to parent's nursing simultaneously.The environment and diaper in diaper area
The morbidity of dermatitis is closely related, it is generally the case that the environment representation in diaper area is that humidity is excessively high, urine, excrement residual, diaper pair
The friction etc. of skin.Protease in excrement can degrade cuticula albumen and cause inflammation, in addition, remaining urine causes
PH is increased, and can upset Stratum corneum lipids and ceramide overall structure and function.The barrier that these factors will cause skin lacks
Damage, causes the high osmosis of skin, and releasing stimulus atopic dermatitis disease.The risk factor of diaper dermatitis is comprehensive, treatment
Scheme is also varied, and treatment is protected mainly around two objectives: (1) promoting the reparation of damage skin；(2) prevention is sent out repeatedly
Make.And skin sexual stimulus is a complicated skin physiology reaction process, main mechanism includes: the damage of (1) skin barrier；
(2) necrosis of skin epidermal cells；(3) the cell-mediated inflammatory reaction of congenital immunity.
The effect of presently commercially available infant diaper rash class product, concentrates on muting sensitive, non-stimulated, skin repair and antibacterial and disappears
Inflammation and other effects lacks the function to skin barrier injury repair.Same concentrate improves diaper rash symptom in terms of patent, lacks to skin
The function of skin barrier reparation, such as moisturizing baby's hip pad lotion and its preparation side of a kind of 201710754110.0 diaper rashes of dispelling
Method is mainly used for improving diaper rash symptom, slows down the slight illness of baby；201710756005.0 a kind of camellia oil baby diaper ointment and
There is preparation method high-efficiency antimicrobial, sterilization, bidirectional modulation to be immunized, safeguard immune, anti-oxidant, anti-inflammatory and accelerate body group
Knit the function of reparation.
Summary of the invention
The present invention in order to overcome the deficiencies of the prior art, designs a kind of wind wind reparation ointment for baby, baby is helped to put as early as possible
The delicate skin of buttock of baby is repaired in the puzzlement of de- diaper rash.
To achieve the above object, it designs a kind of wind wind for baby and repairs ointment and preparation method thereof, it is characterized in that having as follows
The material of mass fraction is made: stearyl alcohol glycyrrhetin 0.01~2.5%wt of acid esters, 0.5%~20%wt of zinc oxide, and thickener 0.5~
3.5%wt, 1.5~25%wt of emollient, the vaseline of 0.1~2%wt of antioxidant and surplus；
Preparation method includes the following steps: S1, and the vaseline mixed oxidization zinc and tapioca of 25~30%wt are put into dissolution kettle
Middle dissolution is stand-by；Remaining vaseline and thickener, stearyl alcohol glycyrrhetin acid esters, Garcinia indica seed rouge are put into emulsifying kettle by S2
Middle emulsification is stand-by；S3 pours into dissolution kettle stand-by raw material in emulsifying kettle, deaeration, and keep vacuum degree be 0.05~
0.10Mpa；The emulsifying kettle for completing step S3 is cooled to 35~60 DEG C by S4, and pours into antioxidant stirring；S5 is stirred evenly,
Discharging.
The thickener is selected from one of glyceryl behenate, eight stearate of polyglycereol -6 or whole.
The emollient is Garcinia indica seed rouge and tapioca.
The antioxidant is selected from one of tocopherol, sunflower seed oil or whole.
The temperature emulsified in the step S2 is 70~85 DEG C, and mixing speed is 10~50rpm, and is kept for 10~30 minutes
Sufficiently dissolution.
Deaeration temperature is maintained at 70~85 DEG C in deaeration vacuum processing in the step S3, and deaeration continues 10~30 minutes,
10~40rpm of mixing speed, 1500~3000rpm of homogeneous speed.Revolving speed is 30~3000rpm.
In the step S4 mixing time be 10~30 minutes, mixing speed be 10~40rpm, homogeneous speed 500~
1000rpm。
The present invention compared with the existing technology, can repair the skin of buttock of baby, it is ensured that baby avoids that diaper rash occurs.
Specific embodiment
Stearyl alcohol glycyrrhetin acid esters due to having imported lipophilic high triacontanol in the molecule used in the present invention, to oil
The dissolubility of rouge significantly improves, and has good compatibility with a variety of lipids and higher alcohol.Can be used for it is sun-proof, brighten, improve,
The purpose of antipruritic, moisturizing.Meanwhile stearyl alcohol glycyrrhetin acid esters have good inflammation-diminishing function, have antibacterial, anti-inflammatory, it is anti-oxidant,
The effect of anti-aging.Compared with enoxolone, stearyl alcohol glycyrrhetin acid esters has lower fusing point and higher vapour pressure, makes it
It is higher than enoxolone by 50% or more in terms of the antibacterial efficiency of skin.And in cosmetics industry, can also mitigate cosmetics or
Toxic side effect of the other factors to skin.
Zinc oxide in the present invention plays anti-inflammatory astringent component, while can have certain UV protective action.The present invention makes
Used time, since zinc oxide is Inorganic white powder, package, grinding is fine and smooth, is dispersed in lotion and acquires a certain degree of difficulty, therefore
It is dissolved first using vaseline mixed oxidization zinc and tapioca, it is ensured that zinc oxide is adequately evenly dispersed in the product.
Glyceryl behenate, eight stearate of polyglycereol -6 in the present invention are used to increase the viscosity for increasing lotion, make
Lotion is not stratified at 40-55 DEG C of relatively-high temperature state, can still maintain initial state.
Garcinia indica seed rouge in the present invention is beneficial compound, facilitates the degeneration for reducing Skin Cell.Prevent skin
Skin is dry, restores skin elasticity, effective wrinkle reduction.There is no greasy feeling, is absorbed by the skin quickly.Cure ulcer and mouth
The cracking of the cracking of lip, hand and sole.Garcinia indica seed rouge is widely used in pharmacy and cosmetic industry, also referred to as " Goa
Seed rouge ", can be used for edible oil.Vitamin E rich in is suitable for skin or hair care.Garcinia indica seed rouge is in South India
It is very famous.Garcinia indica seed rouge is very complicated natural seed rouge, contains oleic acid, palmitic acid and stearic acid, has and preferably stablizes
Property.
Tapioca in the present invention is mainly used as the carrier of vaseline, and vaseline is considered as typical cosmetic vehicle,
It is widely used in cosmetics and skin treating.Vaseline can be used as application system, is especially used as oleophylic agent, is also used in liposome formula
In.When local use, vaseline itself only permeates the most surface of cuticula.The most important property of vaseline is the moisturizing of its Stratum Corneum
Effect, this will be attributed to its opposite Occlusive effect.Therefore, vaseline is the standard that aquation and barrier repair comparative test
Excipient.
Tocopherol and sunflower seed oil in the present invention are a kind of antioxidants of compounding, are given birth to containing natural mixing
Phenol is educated, provides and is effectively protected for the oxidizing component in cosmetic formulations.
Embodiment one:
Choose the stearyl alcohol glycyrrhetin acid esters of 0.2%wt, the zinc oxide of 15%wt, the glyceryl behenate and polyglycereol -6 of 3%wt
Eight stearates, 5%wt Garcinia indica seed oil, 0.5%wt tocopherol and sunflower seed oil, the tapioca and 73.3%wt of 3%wt
Vaseline.
Vaseline is divided into the 20%wt and 53.3%wt that two parts account for total weight respectively, first by the vaseline of 53.3%wt, glycerol
Eight stearate of behenate and polyglycereol -6, stearyl alcohol glycyrrhetin acid esters and Garcinia indica seed oil are put into emulsifying kettle, heating
To 80 DEG C, revolving speed 30rpm, is kept for 15 minutes and sufficiently dissolved, while another part vaseline, zinc oxide and tapioca being put into
In dissolution kettle, after then merging two sections of material, 80 DEG C of temperature is kept, is stirred 15 minutes, is then cooled to 50 DEG C, is added
Tocopherol and sunflower seed oil, discharge after mixing evenly.
Embodiment two:
Choose the stearyl alcohol glycyrrhetin acid esters of 0.05%wt, the zinc oxide of 15%wt, the glyceryl behenate and polyglycereol -6 of 3%wt
Eight stearates, 5%wt Garcinia indica seed oil, 0.5%wt tocopherol and sunflower seed oil, the tapioca and 73.45%wt of 3%wt
Vaseline.
Vaseline is divided into the 20%wt and 53.45%wt that two parts account for total weight respectively, first by the vaseline of 53.45%wt, sweet
Eight stearate of oily behenate and polyglycereol -6, stearyl alcohol glycyrrhetin acid esters and Garcinia indica seed oil are put into emulsifying kettle, are added
Heat is kept for 15 minutes and is sufficiently dissolved to 80 DEG C, revolving speed 30rpm, while another part vaseline, zinc oxide and tapioca being put
Into dissolution kettle, after then merging two sections of material, 80 DEG C of temperature is kept, is stirred 15 minutes, is then cooled to 50 DEG C, adds
Enter tocopherol and sunflower seed oil, discharges after mixing evenly.
Claims (7)
1. a kind of wind wind for baby repairs ointment and preparation method thereof, it is characterized in that there is the material of following mass fraction to be made: hard
Lipidol glycyrrhetin 0.01~2.5%wt of acid esters, 0.5%~20%wt of zinc oxide, 0.5~3.5%wt of thickener, emollient 1.5~25%
Wt, the vaseline of 0.1~2%wt of antioxidant and surplus；
Preparation method includes the following steps:
The vaseline mixed oxidization zinc and tapioca of 25~30%wt are put into dissolution kettle and dissolve for use by S1；S2, will be remaining
Vaseline and thickener, stearyl alcohol glycyrrhetin acid esters, Garcinia indica seed rouge are put into emulsifying kettle and are emulsified for use；S3, by dissolution kettle
Stand-by raw material pours into emulsifying kettle, deaeration, and keeping vacuum degree is 0.05~0.10Mpa；S4 will complete the emulsification of step S3
Kettle is cooled to 35~60 DEG C, and pours into antioxidant stirring；S5 is stirred evenly, discharging.
2. a kind of wind wind for baby according to claim 1 repairs ointment and preparation method thereof, it is characterized in that: the thickening
Agent is selected from one of glyceryl behenate, eight stearate of polyglycereol -6 or whole.
3. a kind of wind wind for baby according to claim 1 repairs ointment and preparation method thereof, it is characterized in that: the moisturizing
Agent is Garcinia indica seed rouge and tapioca.
4. a kind of wind wind for baby according to claim 1 repairs ointment and preparation method thereof, it is characterized in that: the antioxygen
Agent is selected from one of tocopherol, sunflower seed oil or whole.
5. a kind of wind wind for baby according to claim 1 repairs ointment and preparation method thereof, it is characterized in that the step
The temperature emulsified in S2 is 70~85 DEG C, and mixing speed is 10~50rpm, and keeps sufficiently dissolution in 10~30 minutes.
6. a kind of wind wind for baby according to claim 1 repairs ointment and preparation method thereof, it is characterized in that the step
Deaeration temperature is maintained at 70~85 DEG C in deaeration vacuum processing in S3, and deaeration continues 10~30 minutes, and mixing speed 10~
40rpm, homogeneous 1500~3000rpm of speed, revolving speed are 30~3000rpm.
7. a kind of wind wind for baby according to claim 1 repairs ointment and preparation method thereof, it is characterized in that the step
Mixing time is 10~30 minutes in S4, and mixing speed is 10~40rpm, 500~1000rpm of homogeneous speed.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811331452.2A CN109276470A (en) | 2018-11-09 | 2018-11-09 | A kind of wind wind reparation ointment for baby |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811331452.2A CN109276470A (en) | 2018-11-09 | 2018-11-09 | A kind of wind wind reparation ointment for baby |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109276470A true CN109276470A (en) | 2019-01-29 |
Family
ID=65175849
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811331452.2A Pending CN109276470A (en) | 2018-11-09 | 2018-11-09 | A kind of wind wind reparation ointment for baby |
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| CN (1) | CN109276470A (en) |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105997718A (en) * | 2016-07-08 | 2016-10-12 | 广州科玛生物科技股份有限公司 | Infant hip care cream and preparation method thereof |
-
2018
- 2018-11-09 CN CN201811331452.2A patent/CN109276470A/en active Pending
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN105997718A (en) * | 2016-07-08 | 2016-10-12 | 广州科玛生物科技股份有限公司 | Infant hip care cream and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 贝亲母婴用品（上海）有限公司: "贝亲婴儿屁屁修护软膏", 《国产非特殊用途化妆品备案信息服务平台》 * |
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Application publication date: 20190129 |