CN109260550B - Contrast agent microbubble oscillation pushing injection device - Google Patents

Contrast agent microbubble oscillation pushing injection device Download PDF

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Publication number
CN109260550B
CN109260550B CN201811277063.6A CN201811277063A CN109260550B CN 109260550 B CN109260550 B CN 109260550B CN 201811277063 A CN201811277063 A CN 201811277063A CN 109260550 B CN109260550 B CN 109260550B
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China
Prior art keywords
contrast agent
groove
injection
microbubble
push rod
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CN201811277063.6A
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CN109260550A (en
Inventor
刘俐
胡会英
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Peking University Shenzhen Hospital
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Peking University Shenzhen Hospital
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The invention discloses a contrast agent microbubble oscillation injection device; comprises a micro-bubble injector and an automatic injection pump; the microbubble injector comprises an injection needle, a contrast agent injection catheter, a contrast agent microbubble component, an injection cylinder for containing microbubble type contrast agent and a piston type push rod; the liquid inlet end of the injection needle is connected with the liquid outlet end of the contrast agent injection catheter; the liquid inlet end of the contrast agent injection catheter is connected with the liquid outlet end of the contrast agent micro-bubble component; the liquid inlet end of the contrast agent micro-bubble component is connected with the liquid outlet end of the injection cylinder; the connecting end of the piston type push rod extends into the liquid inlet end of the injection cylinder, and the piston type push rod is fixed on the automatic push injection pump. The effect is as follows: the invention can conveniently and efficiently prepare fully-oscillated microbubble contrast agent, and inject the microbubble contrast agent into a patient, can clearly develop focus parts and peripheral tissue areas in the patient, simultaneously keep the contrast agent to continuously oscillate, and keep the concentration of microbubbles for continuously infusing the contrast agent at a constant speed to be balanced and stable in a longer contrast time according to a preset push injection speed, thereby improving the enhancement development effect of the focus parts.

Description

Contrast agent microbubble oscillation pushing injection device
Technical Field
The invention relates to the technical field of medical care products, in particular to a contrast agent microbubble oscillation injection device.
Background
Contrast agents, as their name suggests, are also known as contrast agents, which are chemicals that are injected or administered into human tissues and organs to enhance the image viewing effect. The density of these articles is typically higher or lower than that of the surrounding tissue, and the contrast produced displays images with certain instruments, such as iodine formulations and barium sulfate commonly used for X-ray visualization, to facilitate visualization of the lesion site.
Clinically, for the use of the microbubble type contrast agent, the microbubble type contrast agent is generally filled into a traditional syringe for current preparation, and the corresponding syringe is required to be continuously shaken or vibrated in the current preparation process, so that the microbubble type contrast agent contained in the syringe can generate more microbubbles to facilitate the development of focus positions, and after the current preparation is finished, the prepared microbubble type contrast agent is directly injected into peripheral blood vessels of the focus positions of a patient.
The operation mode has a certain defect and deficiency although the operation mode is widely used.
Specifically, on one hand, the prepared microbubble type contrast agent becomes still when being injected, so that the generated microbubbles quickly disappear, so that the following microbubble type contrast agent has less bubbles and cannot achieve a good focus developing effect when being injected into a blood vessel of a patient, on the other hand, the prepared microbubble type contrast agent is manually injected, so that the injection speed is not well controlled, a moment of injection is finished, a doctor cannot observe a focus part developing image and the injection speed is slow, so that the microbubbles of the microbubble type contrast agent remained in the blood vessel of the patient are less, and the quick developing of the focus part is inconvenient.
Thus, the prior art is in need of improvement.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide a contrast agent microbubble oscillation injection device.
The technical scheme adopted for solving the problems in the prior art is as follows: the microbubble injector comprises an injection needle, a contrast agent injection catheter, a contrast agent microbubble component, an injection cylinder for injecting microbubble type contrast agent, and a piston type push rod matched with the injection cylinder for injecting the contrast agent, wherein both ends of the injection cylinder are formed into an opening; wherein,
The liquid inlet end of the injection needle is connected with the liquid outlet end of the contrast agent injection catheter; the liquid inlet end of the contrast agent injection catheter is detachably connected with the liquid outlet end of the contrast agent micro-bubble component; the liquid inlet end of the contrast agent micro-bubble component is detachably connected with the liquid outlet end of the injection cylinder; the connecting end of the piston type push rod extends into the liquid inlet end of the injection cylinder.
The following further describes the above technical scheme:
Preferably, the contrast agent micro-bubble component comprises a cylinder body with the outer diameter matched with the outer diameter of the injection cylinder, an ultrasonic oscillation piece arranged in the cylinder body and an ultrasonic generator fixed on the outer wall of the cylinder body and connected with the ultrasonic oscillation piece; wherein,
The liquid inlet end of the cylinder body is opened and is in threaded connection with the liquid outlet end of the injection cylinder; the liquid outlet end of the cylinder body is provided with a luer taper head which is suitable for being inserted into the liquid inlet end of the contrast agent injection catheter.
Preferably, the outer wall of the injection cylinder is provided with scales along the length direction; the inner wall of the liquid outlet end of the injection cylinder is provided with a circle of inner edge for blocking the connecting end of the piston type push rod.
Preferably, a circle of ear seats A are arranged on the outer wall of the liquid inlet end of the injection cylinder in a surrounding manner; the outer wall ring at the tail end of the piston type push rod is provided with a circle of ear seats B.
Preferably, the automatic injection pump is used for driving the piston type push rod to push into the injection cylinder at a constant speed; wherein,
The piston type push rod is detachably fixed on the automatic push injection pump.
Preferably, the automatic injection pump comprises a pump body, a pushing mechanism which is arranged at the rear end of the pump body and can move forwards and backwards and is used for automatically pushing the piston push rod forwards, and a main controller which is arranged in the pump body and is used for driving the pushing mechanism to work; wherein,
The side end face of the pump body is provided with a groove A which is close to the lower part of the pump body and is suitable for accommodating the contrast agent micro-bubble component and the injection cylinder connected with the contrast agent micro-bubble component along the front-back direction; the lower end of the pump body is internally provided with a groove B which is suitable for accommodating the piston type push rod along the front-back direction;
The pushing mechanism comprises a driving motor, a screw rod and a pushing block, wherein the driving motor is connected with the main controller, is arranged in the front of the groove B, is fixedly arranged on a rotating shaft at the rear end of the driving motor along the front-rear direction, and is sleeved outside the screw rod in a threaded manner and can slide back and forth, and the pushing block is clamped in the groove B;
The front end of the groove B is communicated with the rear end of the groove A, and the outer diameter of the groove B is larger than that of the groove A, so that the part of the front end of the groove B, which is not communicated with the rear end of the groove A, is formed into an abutting wall;
When the contrast agent micro-bubble component and the injection cylinder are accommodated in the groove A, the ear seat A of the injection cylinder is positioned in the groove B, and the front end surface of the ear seat A abuts against the abutting wall; the piston type push rod is accommodated in the groove B and is positioned outside the screw rod; the rear end face of the ear seat B of the piston type push rod is abutted with the front end face of the pushing block.
Preferably, the groove B is provided with a rear wall, the front end face of the rear wall is fixedly provided with a rotating seat, and the rear end of the screw rod is rotatably and fixedly arranged on the rotating seat; the upper edge of the groove B is downwards fixedly provided with a limit strip A along the length direction of the groove B, and the lower edge of the groove B is upwards fixedly provided with a limit strip B along the length direction of the groove B; the pushing block can slide back and forth and is clamped in the groove B and limited by the limiting strip A and the limiting strip B.
Preferably, an L-shaped clamping plate is fixedly arranged on the side end surface of the pump body outside the rear lower end of the groove A;
when the injection cylinder is clamped in the groove A, the outer wall of the injection cylinder is propped against the inner wall of the L-shaped clamping plate.
Preferably, the groove A is provided with a front wall, and a clamping groove is formed in the middle of the front wall from front to back; the contrast agent injection catheter is clamped in the clamping groove, the liquid outlet end of the contrast agent injection catheter is arranged outside the clamping groove and connected with the liquid inlet end of the injection needle, and the liquid inlet end of the contrast agent injection catheter extends into the groove A from the clamping groove and is connected with the luer taper at the front end of the barrel.
Preferably, a limit ring for enclosing the ear seat B is arranged forward on the front end surface of the pushing block, and the inner diameter of the limit ring is adapted to the outer diameter of the ear seat B.
The beneficial effects of the invention are as follows:
In the implementation, the microbubble injector comprises an injection needle, a contrast agent injection catheter, a contrast agent microbubble component, an injection cylinder for containing microbubble type contrast agent and a piston type push rod matched with the injection cylinder for injecting the contrast agent, wherein the injection needle, the contrast agent injection catheter and the contrast agent microbubble component are sequentially connected, so that when the microbubble type injection device is used, the microbubble type contrast agent is arranged in the injection cylinder, the contrast agent microbubble component and the injection cylinder are connected, the piston type push rod is manually pushed in advance, so that the microbubble type contrast agent in the injection cylinder fills the contrast agent microbubble component, then the contrast agent microbubble component is started, the microbubble type contrast agent filled in the injection cylinder continuously foams, and then the piston type push rod is continuously pushed, so that a large amount of microbubble type contrast agent can be filled in the blood vessel of a patient in a real time, and the peripheral area of a patient can be developed, and the invention has a good practical effect.
Secondly, in the technical scheme, the invention also comprises an automatic injection pump for driving the piston push rod to push into the injection cylinder at a constant speed; the piston type push rod is detachably and fixedly arranged on the automatic push injection pump, so when the automatic push injection pump is used, the piston type push rod can be pushed forward at a constant speed by starting the automatic push injection pump, so that the microbubble type contrast agent in the injection cylinder can be pushed into the blood vessel of a patient at a constant speed after passing through the contrast agent microbubble component, the push injection time is not too short, so that a doctor can not observe a focus part development image and the push injection time is not too long, the push injection speed is slow, the microbubble type contrast agent microbubbles remained in the blood vessel of the patient are less, the focus part is inconvenient to develop rapidly, and the method can be used for injecting the microbubble type contrast agent with microbubbles into the blood vessel of the patient at a constant speed according to the preset speed, so that the contrast effect is good, and the doctor can observe the focus part development image conveniently, so that the doctor can carry out subsequent disease diagnosis on the patient more conveniently, and further, the use effect of the invention can be optimized.
Drawings
FIG. 1 is a schematic view of the overall planar structure of the microbubble injector according to the embodiment of the present invention;
FIG. 2 is a cross-sectional view of the contrast media microbubble element coupled to the syringe barrel, in accordance with an embodiment of the present invention;
FIG. 3 is a schematic view of the overall planar structure of the automatic bolus pump according to the embodiment of the present invention;
FIG. 4 is a schematic view of the overall planar structure of the contrast agent microbubble oscillation bolus device of the present invention;
the achievement of the objects, functional features and advantages of the present invention will be further described with reference to the accompanying drawings, in conjunction with the embodiments.
Reference numerals:
Contrast agent microbubble oscillation bolus device 1000;
A microbubble injector 10;
An injection needle 101;
a contrast injection catheter 102;
A contrast agent microbubble member 103;
A cylinder 1031; luer taper 10311; internal threads 10312; a seal ring 10313; an ultrasonic oscillation piece 1032; an ultrasonic generator 1033;
a syringe 104;
An external thread 1041; a scale 1042; an inner edge 1043; ear mount a1044; living body
A plug type push rod 105;
Ear mount B1051;
An automatic bolus pump 20;
A pump body 201;
Groove a2011; a front wall 20111; a clamping groove 20112; groove B2012; abutment wall 20121; a rear wall 20122; a swivel base 20123; limit bar a20124; limit bar B20125; an L-shaped clamping plate 2013;
A pushing mechanism 202;
a drive motor 2021; a rotation shaft 2022; a screw 2023; a push block 2024; stop collar 20241.
Detailed Description
The following detailed description of the present invention will be given with reference to the accompanying drawings and specific embodiments, so as to more clearly and intuitively understand the essence of the present invention.
As shown in connection with fig. 1, 2, 3 and 4;
The invention provides a contrast agent microbubble oscillation pushing device 1000, which comprises a microbubble injector 10, wherein the microbubble injector 10 comprises an injection needle 101, a contrast agent injection catheter 102, a contrast agent microbubble component 103, an injection cylinder 104 for injecting microbubble type contrast agent, and a piston push rod 105 matched with the injection cylinder 104 for pushing the contrast agent, wherein both ends of the injection cylinder 104 are formed into openings;
Wherein the liquid inlet end of the injection needle 101 is connected with the liquid outlet end of the contrast agent injection catheter 102; the liquid inlet end of the contrast medium injection catheter 102 is detachably connected with the liquid outlet end of the contrast medium micro-bubble component 103; the liquid inlet end of the contrast agent micro-bubble component 103 is detachably connected with the liquid outlet end of the injection cylinder 104; the connecting end of the piston push rod 105 extends into the liquid inlet end of the injection cylinder 104.
Based on the above, it is clear that, in the embodiment of the present invention, since the microbubble injector 10 is provided, the microbubble injector 10 includes the injection needle 101, the contrast medium injection catheter 102, the contrast medium microbubble member 103, the syringe 104 for injecting the microbubble type contrast medium, and the plunger 105 matched with the syringe 104 for injecting the contrast medium, which are sequentially connected.
Thus, when in use, the contrast agent microbubble member and the syringe 104 are disassembled, the microbubble type contrast agent is arranged on the syringe 104, the contrast agent microbubble member and the syringe 104 are connected, the piston push rod 105 is manually pushed and injected first, so that the microbubble type contrast agent in the syringe 104 fills the contrast agent microbubble member 103, then the contrast agent microbubble member 103 is opened, so that the filled microbubble type contrast agent continuously foams, and then the piston push rod 105 is continuously pushed, so that the microbubble type contrast agent which is currently matched and generates a large amount of microbubbles is injected into the blood vessel of a patient through the injection needle 101 in real time, and the focus part and the surrounding tissue area of the patient can be clearly developed later.
Furthermore, the invention has strong practicability and good use effect.
It should be emphasized that, in the specific implementation, the contrast agent microbubble component 103 of the present invention includes a cylinder 1031 having an outer diameter adapted to the outer diameter of the syringe 104, an ultrasonic oscillation piece 1032 disposed in the cylinder 1031, and an ultrasonic generator 1033 fixed to the outer wall of the cylinder 1031 and connected to the ultrasonic oscillation piece 1032;
Wherein, the liquid inlet end of the cylinder 1031 is formed as an opening and is in threaded connection with the liquid outlet end of the syringe 104; the liquid outlet end of the cylinder 1031 is provided with a luer taper 10311 adapted to be inserted into the liquid inlet end of the contrast injection catheter 102.
Specifically, the liquid inlet end of the cylinder 1031 is provided with an internal thread 10312, the liquid outlet end of the injection cylinder 104 is provided with an external thread 1041 meshed with the internal thread, and a sealing ring 10313 is adhered on the inner wall of the cylinder 1031 at the tail end of the internal thread 1041;
In this way, the cylinder 1031 and the syringe 104 are screwed together, so that the connection is firm, and the connection tightness between the cylinder 1031 and the syringe is good, and the leakage is avoided.
In the specific implementation, a via hole is formed in the outer wall of the cylinder 1031, the ultrasonic generator 1033 is fixed to the outer wall of the cylinder 1031, and is connected to the ultrasonic oscillating piece 1032 in the cylinder 1031 through a signal wire passing through the via hole, and a gap between the signal wire and the via hole is filled and sealed by medical glue when the signal wire passes through the via hole.
Further, in this embodiment, the outer wall of the syringe 104 is provided with graduations 1042 along the length direction thereof; the inner wall of the liquid outlet end of the injection tube 104 is provided with a circle of inner edge 1043 for blocking the connection end of the piston push rod 105.
Therefore, on one hand, referring to the scale 1042, it is convenient for the medical staff to control the injection amount of the microbubble type contrast medium injected into the blood vessel at the periphery of the focus of the patient, and on the other hand, the inner edge 1043 is provided to facilitate the blocking of the piston push rod 105, so as to avoid the pushing out of the connecting end and the damage of the ultrasonic oscillation sheet 1032, so that the invention has good use reliability.
Furthermore, in the specific implementation, a ring of ear seats a1044 is disposed around the outer wall of the liquid inlet end of the syringe 104; the outer wall of the tail end of the piston type push rod 105 is provided with a circle of lugs B1051 in a ring mode.
In this way, the ear seat a1044 and the ear seat B1051 are suitable for the medical staff to hold the hands, so that the medical staff can conveniently operate the invention.
Preferably, in practice, the present invention further comprises an automatic bolus pump 20 for driving the plunger 105 at a constant velocity into the barrel 104;
wherein, the piston type push rod 105 is detachably fixed on the automatic injection pump 20.
Thus, when the present invention is used, the automatic injection pump 20 is started to push the piston rod 105 forward at a constant speed, so that the microbubble type contrast agent in the syringe 104 can be injected into the blood vessel of the patient at a constant speed after passing through the contrast agent microbubble component 103, and the injection time is not too short, so that the doctor can not observe the image of the focus part and the injection time is not too long, and the injection speed is slow, so that the number of microbubble type contrast agent microbubbles remained in the blood vessel of the patient is small, and the quick development of the focus part is inconvenient.
Furthermore, the invention can make the microbubble type contrast agent which generates microbubbles injected into the blood vessel of the patient at a constant speed according to the preset speed, so that the contrast effect is good, and the contrast time is long, thereby facilitating the doctor to observe the developed image of the focus part, and facilitating the doctor to carry out the subsequent diagnosis of the illness state of the patient.
In short, the invention has the function of foaming the contrast agent, can keep the contrast agent continuously oscillating, and keeps the concentration of the microbubbles continuously infusing the contrast agent at a constant speed balanced and stable in a longer contrast time according to the preset pushing speed, thereby improving the enhanced developing effect of the focus part and clearly displaying the blood flow perfusion condition of focus tissues.
Furthermore, the use effect of the invention can be optimized.
Preferably, in this embodiment, the automatic injection pump 20 includes a pump body 201, a pushing mechanism 202 disposed at the rear end of the pump body 201 and capable of moving back and forth to automatically push the piston push rod 105 forward, and a main controller disposed in the pump body 201 to drive the pushing mechanism 202 to work;
Wherein, a groove a2011 adapted to accommodate the contrast agent microbubble member 103 and the syringe 104 connected thereto is formed in the side end surface of the pump body 201 near the lower portion thereof along the front-rear direction; the rear lower end of the pump body 201 is provided with a groove B2012 which is suitable for accommodating the piston push rod 105 inwards along the front-rear direction;
The pushing mechanism 202 includes a driving motor 2021 connected to the main controller and disposed in front of the recess B2012, a screw 2023 fixedly disposed on a rotating shaft 2022 at the rear end of the driving motor 2021 along the front-rear direction, and a pushing block 2024 screwed on the screw 2023 and slidably engaged in the recess B2012;
The front end of the groove B2012 is communicated with the rear end of the groove a2011, and the outer diameter of the groove B2012 is larger than the outer diameter of the groove a2011, so that a portion of the front end of the groove B2012, which is not communicated with the rear end of the groove a2011, is formed as an abutment wall 20121;
When the contrast agent microbubble member 103 and the syringe 104 are accommodated in the groove a2011, the ear seat a1044 of the syringe 104 is positioned in the groove B2012, and the front end surface thereof abuts against the abutment wall 20121; the piston type push rod 105 is accommodated in the groove B2012 and is positioned outside the screw 2023; the rear end surface of the ear seat B1051 of the piston rod 105 abuts against the front end surface of the push block 2024.
The groove B2012 has a rear wall 20122, a rotating base 20123 is fixedly disposed on a front end surface of the rear wall 20122, and a rear end of the screw 2023 is rotatably fixedly disposed on the rotating base 20123; the upper edge of the groove B2012 is fixedly provided with a limit strip A20124 downwards along the length direction thereof, and the lower edge of the groove B2012 is fixedly provided with a limit strip B20125 upwards along the length direction thereof; the pushing block 2024 is slidably disposed in the groove B2012, and is limited by the limiting strip a20124 and the limiting strip B20125.
Meanwhile, an L-shaped clamping plate 2013 is fixedly arranged on the side end surface of the pump body 201 outside and upwards at the rear lower end of the groove a 2011;
When the syringe 104 is clamped in the groove a2011, the outer wall of the syringe 104 abuts against the inner wall of the L-shaped clamping plate 2013.
The groove a2011 has a front wall 20111, and a clamping groove 20112 is formed in the middle of the front wall 20111 from front to back; the contrast medium injection catheter 102 is clamped in the clamping groove 20112, a liquid outlet end of the contrast medium injection catheter is arranged outside the clamping groove 20112 and connected with a liquid inlet end of the injection needle 101, and the liquid inlet end of the contrast medium injection catheter extends into the groove A2011 from the clamping groove 20112 and is connected with the luer taper head 10311 at the front end of the injection barrel 104.
In addition, a limit ring 20241 for enclosing the ear mount B1051 is disposed forward of the front end surface of the pushing block 2024, and an inner diameter of the limit ring 20241 is adapted to an outer diameter of the ear mount B1051.
Based on the above, it can be clarified that:
On the one hand, when the contrast agent micro-bubble member 103 and the syringe 104 connected thereto are fastened in the groove a2011, the front end surface of the ear seat a1044 abuts against the abutment wall 20121, the rear end surface of the ear seat B1051 abuts against the front end surface of the pushing block 2024, and the outer wall of the syringe 104 abuts against the inner wall of the L-shaped fastening plate 2013, so that the micro-bubble injector 10 is firmly fastened and is not easy to shift.
On the other hand, the present invention adopts the principle of screw driving to control the pushing of the piston pushing rod 105, that is, the pushing block 2024 may slide back and forth along with the rotation of the screw 2023, so that the piston pushing rod 105 is pushed, and the pushing block 2024 is clamped in the groove B2012 and limited by the limiting strips a20124 and B20125, so that the piston pushing rod is not easy to shift.
Furthermore, the stop collar 20241 keeps the ear mount B1051 in position, so that the piston rod 105 is preferably not easily displaced.
Furthermore, the invention has good use reliability.
It should be noted that, in the implementation, the automatic bolus pump 20 of the present invention may be replaced by a conventional syringe pump, and the functions are equivalent, which will not be described in detail herein.
Other embodiments, etc., are not illustrated herein.
In conclusion, the invention has the advantages of simple integral structure, easy implementation, easy operation, strong practicability and strong specialization, so that the invention has very good market popularization value, and can be very popular and effectively popularized.
The foregoing description is only of the preferred embodiments of the present invention, and is not intended to limit the scope of the invention, and all changes in the equivalent structure or equivalent flow, or direct or indirect application in other related technical fields, are included in the scope of the invention.

Claims (8)

1. A contrast agent microbubble oscillation bolus device, characterized by: the device comprises a microbubble injector, a pressure sensor and a pressure sensor, wherein the microbubble injector comprises an injection needle, a contrast agent injection catheter, a contrast agent microbubble component, an injection cylinder for placing microbubble type contrast agent, and a piston type push rod matched with the injection cylinder for injecting the contrast agent, wherein both ends of the injection cylinder are formed into an opening; wherein,
The liquid inlet end of the injection needle is connected with the liquid outlet end of the contrast agent injection catheter; the liquid inlet end of the contrast agent injection catheter is detachably connected with the liquid outlet end of the contrast agent micro-bubble component; the liquid inlet end of the contrast agent micro-bubble component is detachably connected with the liquid outlet end of the injection cylinder; the connecting end of the piston type push rod extends into the liquid inlet end of the injection cylinder;
The contrast agent micro-bubble component comprises a cylinder body with the outer diameter matched with the outer diameter of the injection cylinder, an ultrasonic oscillation piece arranged in the cylinder body, and an ultrasonic generator fixed on the outer wall of the cylinder body and connected with the ultrasonic oscillation piece; wherein,
The liquid inlet end of the cylinder body is opened and is in threaded connection with the liquid outlet end of the injection cylinder; the liquid outlet end of the cylinder body is provided with a luer taper head which is suitable for being inserted into the liquid inlet end of the contrast agent injection catheter;
the outer wall of the injection cylinder is provided with scales along the length direction; the inner wall of the liquid outlet end of the injection cylinder is provided with a circle of inner edge for blocking the connecting end of the piston type push rod;
the ultrasonic generator is adhered to the outer wall of the cylinder body, the ultrasonic generator is connected with the ultrasonic oscillation piece in the cylinder body through a signal wire penetrating through the through hole, and when the signal wire penetrates through the through hole, a gap between the signal wire and the through hole is filled and sealed by medical glue.
2. The contrast microbubble oscillation bolus device as defined in claim 1, wherein: a circle of ear seats A are arranged on the outer wall of the liquid inlet end of the injection cylinder in a surrounding manner; the outer wall ring at the tail end of the piston type push rod is provided with a circle of ear seats B.
3. The contrast microbubble oscillation bolus device as defined in claim 2, wherein: the automatic injection pump is used for driving the piston type push rod to push into the injection cylinder at a constant speed; wherein,
The piston type push rod is detachably fixed on the automatic push injection pump.
4. The contrast microbubble oscillation bolus device as recited in claim 3, further characterized by: the automatic injection pump comprises a pump body, a pushing mechanism which is arranged at the rear end of the pump body and can move forwards and backwards and is used for automatically pushing the piston type push rod forwards, and a main controller which is arranged in the pump body and is used for driving the pushing mechanism to work; wherein,
The side end face of the pump body is provided with a groove A which is close to the lower part of the pump body and is suitable for accommodating the contrast agent micro-bubble component and the injection cylinder connected with the contrast agent micro-bubble component along the front-back direction; the lower end of the pump body is internally provided with a groove B which is suitable for accommodating the piston type push rod along the front-back direction;
The pushing mechanism comprises a driving motor, a screw rod and a pushing block, wherein the driving motor is connected with the main controller, is arranged in the front of the groove B, is fixedly arranged on a rotating shaft at the rear end of the driving motor along the front-rear direction, and is sleeved outside the screw rod in a threaded manner and can slide back and forth, and the pushing block is clamped in the groove B;
The front end of the groove B is communicated with the rear end of the groove A, and the outer diameter of the groove B is larger than that of the groove A, so that the part of the front end of the groove B, which is not communicated with the rear end of the groove A, is formed into an abutting wall;
When the contrast agent micro-bubble component and the injection cylinder are accommodated in the groove A, the ear seat A of the injection cylinder is positioned in the groove B, and the front end surface of the ear seat A abuts against the abutting wall; the piston type push rod is accommodated in the groove B and is positioned outside the screw rod; the rear end face of the ear seat B of the piston type push rod is abutted with the front end face of the pushing block.
5. The contrast microbubble oscillation bolus device as defined in claim 4, further characterized by: the groove B is provided with a rear wall, the front end face of the rear wall is fixedly provided with a rotating seat, and the rear end of the screw rod is rotatably and fixedly arranged on the rotating seat; the upper edge of the groove B is downwards fixedly provided with a limit strip A along the length direction of the groove B, and the lower edge of the groove B is upwards fixedly provided with a limit strip B along the length direction of the groove B; the pushing block can slide back and forth and is clamped in the groove B and limited by the limiting strip A and the limiting strip B.
6. The contrast microbubble oscillation bolus device as defined in claim 4, further characterized by: an L-shaped clamping plate is fixedly arranged on the side end surface of the pump body outside the rear lower end of the groove A;
when the injection cylinder is clamped in the groove A, the outer wall of the injection cylinder is propped against the inner wall of the L-shaped clamping plate.
7. The contrast microbubble oscillation bolus device as defined in claim 4, further characterized by: the groove A is provided with a front wall, and the middle part of the front wall is provided with a clamping groove from front to back; the contrast agent injection catheter is clamped in the clamping groove, the liquid outlet end of the contrast agent injection catheter is arranged outside the clamping groove and connected with the liquid inlet end of the injection needle, and the liquid inlet end of the contrast agent injection catheter extends into the groove A from the clamping groove and is connected with the luer taper at the front end of the barrel.
8. The contrast microbubble oscillation bolus device as defined in claim 4, further characterized by: the front end face of the pushing block is provided with a limit ring for enclosing the ear seat B forwards, and the inner diameter of the limit ring is matched with the outer diameter of the ear seat B.
CN201811277063.6A 2018-10-30 2018-10-30 Contrast agent microbubble oscillation pushing injection device Active CN109260550B (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012213475A (en) * 2011-03-31 2012-11-08 Panasonic Corp Ultrasonic contrast medium infusion set
CN107308522A (en) * 2017-07-31 2017-11-03 北京大学深圳医院 Nerve block injection test device
CN209630351U (en) * 2018-10-30 2019-11-15 北京大学深圳医院 Contrast agent microbubble vibrates infusing device

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE59105805D1 (en) * 1990-12-28 1995-07-27 Byk Gulden Lomberg Chem Fab PHARMACEUTICAL FORM FOR MICROBUBBLE ECHOCONTRASTER.
DE19840532A1 (en) * 1998-08-28 2000-03-09 Schering Ag Syringe filled with ultrasound contrast medium with a mechanical movement device
JP2001046500A (en) * 1999-08-13 2001-02-20 Olympus Optical Co Ltd Medical injection apparatus
WO2004069153A2 (en) * 2003-01-27 2004-08-19 Medrad, Inc. Apparatus, system and method for generating bubbles on demand
US9554826B2 (en) * 2008-10-03 2017-01-31 Femasys, Inc. Contrast agent injection system for sonographic imaging
RU2735993C2 (en) * 2015-12-29 2020-11-11 Бракко Суисс Са Method and device for preparing a suspension of microparticles uniformly distributed in an aqueous liquid carrier
US9861756B1 (en) * 2016-03-08 2018-01-09 Verily Life Sciences Llc Apparatus and methods for tracking administering of medication by syringe
CN205698739U (en) * 2016-05-13 2016-11-23 刘俊英 A kind of cardioangiography syringe
CN107837439B (en) * 2017-12-15 2023-10-17 广东省人民医院(广东省医学科学院) Integrated replaceable injection tube radiography equipment

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2012213475A (en) * 2011-03-31 2012-11-08 Panasonic Corp Ultrasonic contrast medium infusion set
CN107308522A (en) * 2017-07-31 2017-11-03 北京大学深圳医院 Nerve block injection test device
CN209630351U (en) * 2018-10-30 2019-11-15 北京大学深圳医院 Contrast agent microbubble vibrates infusing device

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