CN109260550A - Contrast agent microbubble vibrates infusing device - Google Patents

Contrast agent microbubble vibrates infusing device Download PDF

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Publication number
CN109260550A
CN109260550A CN201811277063.6A CN201811277063A CN109260550A CN 109260550 A CN109260550 A CN 109260550A CN 201811277063 A CN201811277063 A CN 201811277063A CN 109260550 A CN109260550 A CN 109260550A
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CN
China
Prior art keywords
contrast agent
groove
injection tube
injection
push rod
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Pending
Application number
CN201811277063.6A
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Chinese (zh)
Inventor
刘俐
胡会英
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Peking University Shenzhen Hospital
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Peking University Shenzhen Hospital
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Publication date
Application filed by Peking University Shenzhen Hospital filed Critical Peking University Shenzhen Hospital
Priority to CN201811277063.6A priority Critical patent/CN109260550A/en
Publication of CN109260550A publication Critical patent/CN109260550A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/007Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests for contrast media
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/20Automatic syringes, e.g. with automatically actuated piston rod, with automatic needle injection, filling automatically
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/3129Syringe barrels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/315Pistons; Piston-rods; Guiding, blocking or restricting the movement of the rod or piston; Appliances on the rod for facilitating dosing ; Dosing mechanisms
    • A61M5/31511Piston or piston-rod constructions, e.g. connection of piston with piston-rod
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M5/00Devices for bringing media into the body in a subcutaneous, intra-vascular or intramuscular way; Accessories therefor, e.g. filling or cleaning devices, arm-rests
    • A61M5/178Syringes
    • A61M5/31Details
    • A61M5/32Needles; Details of needles pertaining to their connection with syringe or hub; Accessories for bringing the needle into, or holding the needle on, the body; Devices for protection of needles

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  • Health & Medical Sciences (AREA)
  • Vascular Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hematology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Infusion, Injection, And Reservoir Apparatuses (AREA)

Abstract

The present invention discloses contrast agent microbubble oscillation infusing device;Including microvesicle injector and automatically pump is injected;Microvesicle injector include injection needle, contrast agent injection catheter, contrast agent microbubble component, to the injection tube and piston type push rod of device microvesicle type contrast agent;Injection needle liquid feeding end is connected with contrast agent injection catheter outlet end;Contrast agent injection catheter liquid feeding end is connect with contrast agent microbubble component outlet end;Contrast agent microbubble component liquid feeding end is connect with injection tube outlet end;Piston type push rod connecting pin is protruded into injection tube liquid feeding end, and piston type push rod is fixed in injects on pump automatically.Effect: the present invention can convenient and efficient prepare the microbubble contrast agent that sufficiently vibrates, and it injects in patient body, can clearly be developed lesions position in patient body and perienchyma region, contrast agent persistent oscillation is kept simultaneously, and speed is injected according to default, the microbubble concentration for making to continue at the uniform velocity to be transfused contrast agent is kept in balance stabilization in longer contrast time, to improve the enhancing development effect of lesions position.

Description

Contrast agent microbubble vibrates infusing device
Technical field
The present invention relates to medical nursing product technical fields, in particular, being related to a kind of oscillation of contrast agent microbubble injects dress It sets.
Background technique
Contrast agent, as its name suggests, also known as contrast medium is a kind of to inject or take human body for enhancing Imaging Study effect The chemicals of tissue and organ.The density of these products is generally higher or lower than surrounding tissue, is formed by comparison and uses certain A little instruments show images, such as the common Operand of x-ray observation and barium sulfate, specially offered in order to the development of lesions position.
And clinically, the use for the contrast agent of microvesicle type is generally packed into traditional used injection It carries out now matching now in device, then needs that ceaselessly corresponding syringe is rocked or shaken during now matching, so that its The contrast agent of interior accommodated microvesicle type generates more microvesicle and is convenient for the development of lesions position, after now matching, then The contrast agent bolus of the microvesicle type prepared is directly entered into patient's lesions position periphery blood vessel.
For aforesaid operations mode, although it still has certain defect and deficiency using extensively.
Specifically, on the one hand, the contrast agent for the microvesicle type now matched becomes standing again when injecting, and such one Come, generated microvesicle can disappear quickly, the number so that contrast agent of the subsequent microvesicle type when injecting in patient's blood vessel blisters Amount does not have good lesion development effect less, on the other hand, to inject manually, so that injecting the bad control of speed, exists It has injected in a flash and doctor is made to have little time to observe lesions position developed image and cause to retain in disease slowly in the presence of speed is injected The contrast agent microbubble of the microvesicle type of people's blood vessel is few and makes the rapid development for being not easy to lesions position.
Whereby, the prior art has much room for improvement.
Summary of the invention
It is an object of the invention to a kind of contrast agent microbubble oscillations for overcoming the deficiency of the above-mentioned prior art and providing to inject Device.
The present invention solves technical solution used by prior art problem: a kind of contrast agent microbubble oscillation infusing device, Including microvesicle injector, the microvesicle injector include injection needle, contrast agent injection catheter, contrast agent microbubble component, to fill The both ends for setting microvesicle type contrast agent be all formed as open injection tube and matched with the injection tube to inject radiography The piston type push rod of agent;Wherein,
The liquid feeding end of the injection needle is connected with the outlet end of the contrast agent injection catheter;The contrast agent injection catheter The outlet end of liquid feeding end and the contrast agent microbubble component be detachably connected;The liquid feeding end of the contrast agent microbubble component and institute The outlet end for stating injection tube is detachably connected;The connecting pin of the piston type push rod is protruded into the liquid feeding end of the injection tube.
Above technical scheme is further elaborated below:
Preferably, the contrast agent microbubble component includes outer diameter cylinder compatible with the injection tube outer diameter, is set to institute It states the intracorporal supersonic oscillations piece of cylinder and is fixed on the ultrasonic wave hair of the cylinder body outer wall being connected with the supersonic oscillations piece Raw device;Wherein,
The cylinder liquid feeding end is formed as open and is threadedly coupled with the injection tube outlet end;The barrel liquid discharge end is set There is one to be suitable for Rule conehead that the contrast agent injection catheter liquid feeding end plugs.
Preferably, the injection drum outer wall is provided along its length scale;The injection tube outlet end inner wall is equipped with One circle is to keep off the inner edge for setting piston type push rod connecting pin.
Preferably, the injection tube liquid feeding end outer wall is equipped with a circle ear mount A;Piston type push rod end outer wall ring is set There is a circle ear mount B.
It preferably, further include one to drive what the piston type push rod at the uniform velocity promoted into the injection tube to inject automatically Pump;Wherein,
The piston type push rod is removable, and being fixedly arranged on of taking is described injects on pump automatically.
Preferably, it is described automatically inject pump include the pump housing, set on the pump housing rear end be moved forward and backward to forward The pushing mechanism of piston type push rod described in automatic push and intracorporal to drive pushing mechanism work set on the pump Master controller;Wherein,
The pump housing side end face inwardly offers one along the longitudinal direction close to its underpart and is suitable for accommodating the contrast agent microbubble The groove A of component and the coupled injection tube;The pump housing posterior end is provided inwardly with one along the longitudinal direction and is suitable for holding Set the groove B of the piston type push rod;
The pushing mechanism includes the driving motor internal before the groove B being connected with the master controller, edge The screw rod and screw thread that front-rear direction is fixedly arranged in the shaft of the driving motor rear end are socketed on outside the screw rod and can slide back and forth The push block being arranged in the groove B;
The front end of the groove B is connected with the rear end of the groove A, and the outer diameter of the groove B is greater than the groove A Outer diameter so that the front end of the groove B is configured to a contacting wall without the part that is connected with the rear end of the groove A;
The contrast agent microbubble component and the injection tube are when being placed in the groove A, the ear mount A of the injection tube In the groove B, front end face offsets with the contacting wall;The piston type push rod is placed in the groove B, and position In outside the screw rod;The rear end face of the ear mount B of the piston type push rod and the front end face of the push block abut against.
Preferably, the groove B has a rear wall, and the front end face of the rear wall is installed with a rotation seat, the screw rod Rear end is rotatably fixedly arranged on the rotation seat;The upper edge of the groove B is installed with downwards a limit along its length A, the lower edge of the groove B is installed with a positive stop strip B upwards along its length;The push block card capable of sliding back and forth It is limited in groove B, and by the positive stop strip A and positive stop strip B.
Preferably, the pump housing side end face in be installed with upwards outside the posterior end of the groove A L-type fix plate;
When the injection tube is arranged in the groove A, the inner wall of the outer wall of the injection tube and L-type fixing plate It offsets.
Preferably, the groove A has an antetheca, and the middle part of the antetheca offers a card slot from front to back;It is described to make Shadow agent injection catheter is arranged in the card slot, and outlet end is set to outside the card slot and connects with the liquid feeding end of the injection needle It connects, liquid feeding end is stretched in the groove A from the card slot and connect with Rule conehead of the barrel front end.
Preferably, the front end of the push block is equipped with a spacing collar for going along with sb. to guard him the ear mount B phase, the limit forward The internal diameter of circle is adapted with the outer diameter of the ear mount B.
The beneficial effects of the present invention are:
One, a kind of contrast agent microbubble oscillation infusing device provided by the present invention, it is in the specific implementation, micro- because being provided with Injector is steeped, set microvesicle injector includes the injection needle being sequentially connected, contrast agent injection catheter, contrast agent microbubble structure Part, the injection tube to device microvesicle type contrast agent and the piston type to bolus administration of contrast agent that is matched with the injection tube Microvesicle type contrast agent is installed on by push rod in this way, when in use, dismantling the contrast agent microbubble component and the injection tube The injection tube reconnects the good contrast agent microbubble component and the injection tube, first injects the piston type manually and push away Bar is then turned on the contrast agent so that the microvesicle type contrast agent in the injection tube fills the contrast agent microbubble component Microvesicle component is further continued for pushing the piston type push rod, i.e., so that the microvesicle type contrast agent filled in it ceaselessly blisters It may make the microvesicle type contrast agent for a large amount of microvesicles of generation now matched now in real time by injection patient vessel, so that subsequent can be clear Clear lesions position and the perienchyma region developed in patient body, in turn, the present invention is practical, and using effect is good.
Secondly, in the technical scheme, because the invention also includes one to drive the piston type push rod at the uniform velocity described in What is promoted in injection tube injects pump automatically;The piston type push rod is removable, and being fixedly arranged on of taking is described injects on pump automatically, in this way, When using the present invention, start it is described inject pump automatically and the piston type push rod can at the uniform velocity be pushed ahead so that the injection Microvesicle type contrast agent in cylinder is can be according to speed being injected into trouble at the uniform velocity of setting after the contrast agent microbubble component Person's blood vessel will not make doctor have little time to observe lesions position developed image and when to inject so that injecting the time because too short Between will not exist because too long and inject speed slowly the microvesicle type contrast agent microbubble for retaining in patient's blood vessel is caused to lead to inconvenience less In the rapid development of lesions position, in turn, the present invention can accomplish so that generating the microvesicle type contrast agent of microvesicle according to default speed Degree at the uniform velocity by injection patient vessel so that also make contrast time long while contrasting effects are good, in order to which doctor observes disease Stove position developed image, so that more preferable carry out subsequent condition-inference to patient convenient for auxiliary doctor, in turn, use effect of the invention Fruit can reach best.
Detailed description of the invention
Fig. 1 is the integral planar structural schematic diagram of the microvesicle injector in the embodiment of the present invention;
Fig. 2 is the cross-sectional view that the contrast agent microbubble component is connected with the injection tube in the embodiment of the present invention;
Fig. 3 is the integral planar structural schematic diagram for injecting pump automatically in the embodiment of the present invention;
Fig. 4 is the integral planar structural schematic diagram of contrast agent microbubble oscillation infusing device of the present invention;
The embodiments will be further described with reference to the accompanying drawings for the realization, the function and the advantages of the object of the present invention.
Drawing reference numeral:
Contrast agent microbubble vibrates infusing device 1000;
Microvesicle injector 10;
Injection needle 101;
Contrast agent injection catheter 102;
Contrast agent microbubble component 103;
Cylinder 1031;Rule conehead 10311;Internal screw thread 10312;Sealing ring 10313;Supersonic oscillations piece 1032;Ultrasound Wave producer 1033;
Injection tube 104;
External screw thread 1041;Scale 1042;Inner edge 1043;Ear mount A1044;It is living
Plug push rod 105;
Ear mount B1051;
Automatically pump 20 is injected;
The pump housing 201;
Groove A2011;Antetheca 20111;Card slot 20112;Groove B2012;Contacting wall 20121;Rear wall 20122;Rotation seat 20123;Positive stop strip A20124;Positive stop strip B20125;L-type fixes plate 2013;
Pushing mechanism 202;
Driving motor 2021;Shaft 2022;Screw rod 2023;Push block 2024;Spacing collar 20241.
Specific embodiment
Below with reference to the drawings and the specific embodiments technical solution that the present invention will be described in detail, to become apparent from, intuitively Understand invention essence of the invention.
In conjunction with shown in Fig. 1, Fig. 2, Fig. 3 and Fig. 4;
A kind of contrast agent microbubble provided by the present invention vibrates infusing device 1000, including microvesicle injector 10, described micro- Steep injector 10 include injection needle 101, contrast agent injection catheter 102, contrast agent microbubble component 103, to device microvesicle type The both ends of contrast agent be all formed as open injection tube 104 and matched with the injection tube 104 to bolus administration of contrast agent Piston type push rod 105;
Wherein, the liquid feeding end of the injection needle 101 is connected with the outlet end of the contrast agent injection catheter 102;It is described to make The liquid feeding end of shadow agent injection catheter 102 and the outlet end of the contrast agent microbubble component 103 are detachably connected;The contrast agent is micro- The outlet end for steeping the liquid feeding end and the injection tube 104 of component 103 is detachably connected;The connecting pin of the piston type push rod 105 It stretches in the liquid feeding end of the injection tube 104.
Based on described above, it is clear that, a kind of contrast agent microbubble provided by the present invention vibrates infusing device 1000, in the specific implementation, because being provided with microvesicle injector 10, set microvesicle injector 10 includes the injection being sequentially connected Needle 101, contrast agent injection catheter 102, contrast agent microbubble component 103, to device microvesicle type contrast agent injection tube 104 and The piston type push rod 105 to bolus administration of contrast agent matched with the injection tube 104.
In this way, when in use, the contrast agent microbubble component and the injection tube 104 are dismantled, by microvesicle type contrast agent It is installed on the injection tube 104, the good contrast agent microbubble component and the injection tube 104 is reconnected, first injects manually The piston type push rod 105, so that the microvesicle type contrast agent in the injection tube 104 fills the contrast agent microbubble component 103, it is then turned on the contrast agent microbubble component 103, so that the microvesicle type contrast agent filled in it ceaselessly blisters, then The piston type push rod 105 is continued to press on, that is, may make the microvesicle type contrast agent for a large amount of microvesicles of generation now matched now real-time Through the injection needle 101 by injection patient vessel so that subsequent lesions position and its periphery that can clearly develop in patient body Tissue regions.
In turn, the present invention is practical, and using effect is good.
It is emphasized that in the specific implementation, the contrast agent microbubble component 103 of the invention then includes outer diameter and institute It states the compatible cylinder 1031 of 104 outer diameter of injection tube, the supersonic oscillations piece 1032 in the cylinder 1031 and is fixed on The supersonic generator 1033 of 1031 outer wall of cylinder being connected with the supersonic oscillations piece 1032;
Wherein, 1031 liquid feeding end of cylinder is formed as open and is threadedly coupled with 104 outlet end of injection tube;It is described 1031 outlet end of cylinder is equipped with one and is suitable for Rule conehead 10311 that 102 liquid feeding end of contrast agent injection catheter plugs.
Specifically, 1031 liquid feeding end of cylinder be equipped with internal screw thread 10312,104 outlet end of injection tube be equipped with The external screw thread 1041 that the internal screw thread is meshed, and the inner wall of the cylinder 1031 is glued in the end of the internal screw thread 1041 and is equipped with One sealing ring 10313;
In this way, realizing that the cylinder 1031 is threadedly coupled with the injection tube 104, while so that connectivity robustness is good Can also making it, connection sealing is good and avoid leakage each other.
And herein it should be noted that in the specific implementation, 1031 outer wall of cylinder offers a via hole, the ultrasound Wave producer 1033 is to adhere to 1031 outer wall of cylinder, and the signal wire by being arranged in the via hole and the cylinder The supersonic oscillations piece 1032 in 1031 is connected, and the signal wire is when passing through the via hole, with the via hole it Between gap then use medical adhesive filling sealing.
Further, in the present embodiment, 104 outer wall of injection tube is provided along its length scale 1042;It is described 104 outlet end inner wall of injection tube is equipped with a circle to keep off the inner edge 1043 for setting 105 connecting pin of piston type push rod.
So, on the one hand, referring to the scale 1042, patient's lesion peripheral part can be injected convenient for medical staff's control The microvesicle type contrast agent injection rate of blood vessel, on the other hand, set inner edge 1043 to set the piston type convenient for gear and push away Bar 105 pushes up the bad supersonic oscillations piece 1032 to avoid the release of its connecting pin, so that use reliability of the present invention is good.
Furthermore in the specific implementation, the 104 liquid feeding end outer wall of injection tube is equipped with a circle ear mount A1044;The piston 105 end outer wall of formula push rod is equipped with a circle ear mount B1051.
In this way, set ear mount A1044 and ear mount B1051 is then suitable for medical staff's hand and is affectedly bashful, so that being convenient for medical care Personnel manipulate the present invention.
Preferably, in the specific implementation, the invention also includes one to drive the piston type push rod 105 at the uniform velocity to described What is promoted in injection tube 104 injects pump 20 automatically;
Wherein, removable described inject automatically that be fixedly arranged on taken of the piston type push rod 105 pumps on 20.
In this way, in using the present invention, start it is described inject automatically pump 20 can by the piston type push rod 105 at the uniform velocity to It is pushed forward into so that microvesicle type contrast agent in the injection tube 104 is can be according to setting after the contrast agent microbubble component 103 Fixed speed being injected into patient vessel at the uniform velocity will not make doctor have little time to observe lesion so that injecting the time because too short Position developed image and making inject the time will not be too long and exist and inject speed slowly and lead to the microvesicle class for retaining in patient's blood vessel Type contrast agent microbubble quantity leads to the rapid development for being not easy to lesions position less.
In turn, the present invention can accomplish so that generate the microvesicle type contrast agent of microvesicle according to pre-set velocity being injected at the uniform velocity Patient vessel, so that also make contrast time long while contrasting effects are good, in order to which doctor observes lesions position developed image, So that more preferable carry out subsequent condition-inference to patient convenient for auxiliary doctor.
In short, the present invention is also able to maintain contrast agent persistent oscillation while having the function of that contrast agent plays microvesicle, and Speed is injected according to default, the microbubble concentration for making to continue at the uniform velocity to be transfused contrast agent is kept in balance stabilization in longer contrast time, To improve the enhancing development effect of lesions position, more clearly to show the blood perfusion situation of lesion tissue.
In turn, using effect of the invention can reach best.
Preferably, specifically, in the present embodiment, the pump 20 of injecting automatically then includes the pump housing 201, is set to the pump 201 rear end of body be moved forward and backward to piston type push rod 105 described in automatic push forward pushing mechanism 202 and be set to institute State the master controller to drive the work of pushing mechanism 202 in the pump housing 201;
Wherein, 201 side end face of the pump housing inwardly offers one along the longitudinal direction close to its underpart and is suitable for making described in accommodating The groove A2011 of shadow agent microvesicle component 103 and the coupled injection tube 104;201 posterior end of the pump housing is along front and back Direction is provided inwardly with a groove B2012 for being suitable for accommodating the piston type push rod 105;
The pushing mechanism 202 includes the driving internal before the groove B2012 being connected with the master controller Motor 2021, the screw rod 2023 being fixedly arranged in the 2021 rear end shaft 2022 of driving motor along the longitudinal direction and screw thread are socketed on The screw rod 2023 push block 2024 outer and capable of sliding back and forth being arranged in the groove B2012;
The front end of the groove B2012 is connected with the rear end of the groove A2011, and the outer diameter of the groove B2012 Greater than the outer diameter of the groove A2011 so that the front end of the groove B2012 without the rear end phase with the groove A2011 The part of connection is configured to a contacting wall 20121;
The contrast agent microbubble component 103 and the injection tube 104 are when being placed in the groove A2011, the note The ear mount A1044 of shooting cylinder 104 is located in the groove B2012, and front end face offsets with the contacting wall 20121;The piston Formula push rod 105 is placed in the groove B2012, and is located at outside the screw rod 2023;The ear mount of the piston type push rod 105 The rear end face of B1051 and the front end face of the push block 2024 abut against.
Also, the groove B2012 has a rear wall 20122, and the front end face of the rear wall 20122 is installed with a rotation seat 20123, the rear end of the screw rod 2023 is rotatably fixedly arranged on the rotation seat 20123;The upper edge of the groove B2012 It is installed with a positive stop strip A20124 downwards along its length, the lower edge of the groove B2012 is solid upwards along its length Equipped with a positive stop strip B20125;The push block 2024 is capable of sliding back and forth to be arranged in groove B2012, and by the positive stop strip A20124 and positive stop strip B20125 limit.
Meanwhile 201 side end face of the pump housing in be installed with upwards outside the posterior end of the groove A2011 L-type fix plate 2013;
When the injection tube 104 is arranged in the groove A2011, the outer wall of the injection tube 104 and the L-type card The inner wall of solid plate 2013 offsets.
And the groove A2011 has an antetheca 20111, the middle part of the antetheca 20111 offers a card from front to back Slot 20112;The contrast agent injection catheter 102 is arranged in the card slot 20112, and outlet end is set to the card slot 20112 It connect outside and with the liquid feeding end of the injection needle 101, liquid feeding end stretches in the groove A2011 from the card slot 20112 And it is connect with Rule conehead 10311 of 104 front end of injection tube.
In addition, the front end of the push block 2024 is equipped with a spacing collar for going along with sb. to guard him the ear mount B1051 phase forward 20241, the internal diameter of the spacing collar 20241 is adapted with the outer diameter of the ear mount B1051.
Based on described above, can define:
On the one hand, the contrast agent microbubble component 103 and the coupled injection tube 104 are being fastened in the groove When in A2011, the front end face of the ear mount A1044 offsets with the contacting wall 20121, the rear end face of the ear mount B1051 with The front end face of the push block 2024 offsets, and the inner wall that the outer wall of the injection tube 104 fixes plate 2013 with the L-type offsets, So that set stability good and be not easy to shift for the microvesicle injector 10 card.
On the other hand, the present invention controls the push of the piston type push rod 105 using the principle of screw rod transmission, i.e., described Push block 2024 can slide back and forth with the rotation of the screw rod 2023, so as to push the piston type push rod 105, push away because described in It send block 2024 to be arranged in groove B2012, and is limited by the positive stop strip A20124 and positive stop strip B20125, then make It is not easy to shift.
Furthermore the ear mount B1051 phase is gone along with sb. to guard him limit by the spacing collar 20241, so that the piston type push rod 105 is more It is good to be not easy to shift.
In turn, use reliability of the present invention is good.
You need to add is that in the specific implementation, tradition also can be used in the pump 20 of injecting automatically that the present invention is included Used syringe pump be replaced, effect is equivalent, here, not doing more careful explanation then.
Other embodiments etc., illustrate one by one here, also not doing.
In conclusion overall structure of the present invention is simple, easily implement, easy to operate, practical, specificity is strong, so that this hair Bright necessarily to have good market popularization value, the present invention can be very welcome, can effectively be popularized.
The above description is only a preferred embodiment of the present invention, is not intended to limit scope of patent protection of the invention, all Using the transformation of equivalent structure made by description of the invention and accompanying drawing content or equivalent process, it is applied directly or indirectly in it His relevant technical field, is included within the scope of the present invention.

Claims (10)

1. a kind of contrast agent microbubble vibrates infusing device, it is characterised in that: including microvesicle injector, the microvesicle injector includes Injection needle, contrast agent microbubble component, to the both ends of device microvesicle type contrast agent is all formed as opening at contrast agent injection catheter Injection tube and the piston type push rod to bolus administration of contrast agent that is matched with the injection tube;Wherein,
The liquid feeding end of the injection needle is connected with the outlet end of the contrast agent injection catheter;The contrast agent injection catheter into Liquid end and the outlet end of the contrast agent microbubble component are detachably connected;The liquid feeding end and the note of the contrast agent microbubble component The outlet end of shooting cylinder is detachably connected;The connecting pin of the piston type push rod is protruded into the liquid feeding end of the injection tube.
2. contrast agent microbubble according to claim 1 vibrates infusing device, it is characterised in that: the contrast agent microbubble component Including outer diameter cylinder compatible with the injection tube outer diameter, set on the intracorporal supersonic oscillations piece of the cylinder and it is fixed on described The supersonic generator of cylinder body outer wall being connected with the supersonic oscillations piece;Wherein,
The cylinder liquid feeding end is formed as open and is threadedly coupled with the injection tube outlet end;The barrel liquid discharge end is equipped with one Rule conehead plugged suitable for the contrast agent injection catheter liquid feeding end.
3. contrast agent microbubble according to claim 2 vibrates infusing device, it is characterised in that: the injection drum outer wall is along it Length direction is equipped with scale;The injection tube outlet end inner wall is equipped with a circle and sets piston type push rod connecting pin to keep off Inner edge.
4. contrast agent microbubble according to claim 3 vibrates infusing device, it is characterised in that: outside the injection tube liquid feeding end Wall is equipped with a circle ear mount A;Piston type push rod end outer wall is equipped with a circle ear mount B.
5. contrast agent microbubble according to claim 4 vibrates infusing device, it is characterised in that: further include one to drive That states that piston type push rod at the uniform velocity promotes into the injection tube injects pump automatically;Wherein,
The piston type push rod is removable, and being fixedly arranged on of taking is described injects on pump automatically.
6. contrast agent microbubble according to claim 5 vibrates infusing device, it is characterised in that: described to inject pump automatically and include The pump housing, set on the pump housing rear end be moved forward and backward to the pushing mechanism of piston type push rod described in automatic push forward and Set on the intracorporal master controller to drive the pushing mechanism work of the pump;Wherein,
The pump housing side end face inwardly offers one along the longitudinal direction close to its underpart and is suitable for accommodating the contrast agent microbubble component And the groove A of the coupled injection tube;The pump housing posterior end is provided inwardly with one along the longitudinal direction and is suitable for accommodating institute State the groove B of piston type push rod;
The pushing mechanism includes the driving motor internal before the groove B being connected with the master controller, along front and back The screw rod and screw thread that direction is fixedly arranged in the shaft of the driving motor rear end are socketed on outside the screw rod and card capable of sliding back and forth Push block in the groove B;
The front end of the groove B is connected with the rear end of the groove A, and the outer diameter of the groove B is outer greater than the groove A Diameter, so that the front end of the groove B is configured to a contacting wall without the part that is connected with the rear end of the groove A;
When being placed in the groove A, the ear mount A of the injection tube is located at for the contrast agent microbubble component and the injection tube In the groove B, front end face offsets with the contacting wall;The piston type push rod is placed in the groove B, and is located at institute It states outside screw rod;The rear end face of the ear mount B of the piston type push rod and the front end face of the push block abut against.
7. contrast agent microbubble according to claim 6 vibrates infusing device, it is characterised in that: after the groove B has one Wall, the front end face of the rear wall are installed with a rotation seat, and the rear end of the screw rod is rotatably fixedly arranged on the rotation seat;Institute The upper edge for stating groove B is installed with downwards a positive stop strip A along its length, and the lower edge of the groove B is along its length It is installed with a positive stop strip B upwards;The push block is capable of sliding back and forth to be arranged in groove B, and by the positive stop strip A and described Positive stop strip B limit.
8. contrast agent microbubble according to claim 6 vibrates infusing device, it is characterised in that: the pump housing side end face is in institute It states and is installed with L-type fixing plate outside the posterior end of groove A upwards;
When the injection tube is arranged in the groove A, the outer wall of the injection tube fixes the inner wall phase of plate with the L-type It supports.
9. contrast agent microbubble according to claim 6 vibrates infusing device, it is characterised in that: before the groove A has one Wall, the middle part of the antetheca offer a card slot from front to back;The contrast agent injection catheter is arranged in the card slot, is gone out Liquid end is set to outside the card slot and connect with the liquid feeding end of the injection needle, and liquid feeding end stretches to the groove from the card slot It is connect in A with Rule conehead of the barrel front end.
10. contrast agent microbubble according to claim 6 vibrates infusing device, it is characterised in that: the front end of the push block It is equipped with a spacing collar for going along with sb. to guard him the ear mount B phase forward, the internal diameter of the spacing collar and the outer diameter of the ear mount B are mutually fitted Match.
CN201811277063.6A 2018-10-30 2018-10-30 Contrast agent microbubble vibrates infusing device Pending CN109260550A (en)

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Citations (10)

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WO1992011928A1 (en) * 1990-12-28 1992-07-23 Byk Gulden Lomberg Chemische Fabrik Gmbh Dosage form for micro-bubble echo contrast agents
JP2001046500A (en) * 1999-08-13 2001-02-20 Olympus Optical Co Ltd Medical injection apparatus
US20040253183A1 (en) * 2002-01-25 2004-12-16 Uber Arthur E. Apparatus, system and method for generating bubbles on demand
US6966894B1 (en) * 1998-08-28 2005-11-22 Schering Aktiengesellschaft Syringes and injectors incorporating mechanical fluid agitation devices
JP2012213475A (en) * 2011-03-31 2012-11-08 Panasonic Corp Ultrasonic contrast medium infusion set
CN107308522A (en) * 2017-07-31 2017-11-03 北京大学深圳医院 Nerve block injection test device
US9861756B1 (en) * 2016-03-08 2018-01-09 Verily Life Sciences Llc Apparatus and methods for tracking administering of medication by syringe
CN107837439A (en) * 2017-12-15 2018-03-27 广东省人民医院(广东省医学科学院) The replaceable injection tube contrast apparatus of integral type
CN108309413A (en) * 2010-11-09 2018-07-24 费玛塞斯公司 Method and apparatus for ultrasonic examination imaging
CN209630351U (en) * 2018-10-30 2019-11-15 北京大学深圳医院 Contrast agent microbubble vibrates infusing device

Patent Citations (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1992011928A1 (en) * 1990-12-28 1992-07-23 Byk Gulden Lomberg Chemische Fabrik Gmbh Dosage form for micro-bubble echo contrast agents
US6966894B1 (en) * 1998-08-28 2005-11-22 Schering Aktiengesellschaft Syringes and injectors incorporating mechanical fluid agitation devices
JP2001046500A (en) * 1999-08-13 2001-02-20 Olympus Optical Co Ltd Medical injection apparatus
US20040253183A1 (en) * 2002-01-25 2004-12-16 Uber Arthur E. Apparatus, system and method for generating bubbles on demand
CN108309413A (en) * 2010-11-09 2018-07-24 费玛塞斯公司 Method and apparatus for ultrasonic examination imaging
JP2012213475A (en) * 2011-03-31 2012-11-08 Panasonic Corp Ultrasonic contrast medium infusion set
US9861756B1 (en) * 2016-03-08 2018-01-09 Verily Life Sciences Llc Apparatus and methods for tracking administering of medication by syringe
CN107308522A (en) * 2017-07-31 2017-11-03 北京大学深圳医院 Nerve block injection test device
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CN209630351U (en) * 2018-10-30 2019-11-15 北京大学深圳医院 Contrast agent microbubble vibrates infusing device

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