CN109260438A - A kind of wind-damp dispelling Chinese medicine medicine oil and preparation method thereof - Google Patents

A kind of wind-damp dispelling Chinese medicine medicine oil and preparation method thereof Download PDF

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CN109260438A
CN109260438A CN201811337342.7A CN201811337342A CN109260438A CN 109260438 A CN109260438 A CN 109260438A CN 201811337342 A CN201811337342 A CN 201811337342A CN 109260438 A CN109260438 A CN 109260438A
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parts
chinese
oil
radix
wind
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曹君
曹君一
白艳荣
袁慧
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Affiliated Hospital of Shaanxi University of Chinese Medicine
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Affiliated Hospital of Shaanxi University of Chinese Medicine
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    • A61K36/18Magnoliophyta (angiosperms)
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    • A61K36/25Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
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    • A61K35/12Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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Abstract

The invention discloses a kind of wind-damp dispelling Chinese medicine medicine oils and preparation method thereof, which is prepared by the raw material of following parts by weight: 10-20 parts of Radix Notoginseng, 10-20 parts of safflower, 5-15 parts of radix saposhnikoviae, 5-15 parts of excrementum pteropi, 10-15 parts of lopseed, 10-20 parts of the root of Chinese clematis, 5-10 parts of Rhizoma Et Radix Notopterygii, 5-15 parts of caulis trachelospermi, 5-7 parts of frutus cnidii, 3-5 parts of Chinese prickly ash, 5-10 parts of lycopodium calvatum, 10-15 parts of ramulus cinnamomi, 3-6 parts of ginger splices, 1-3 parts of peppermint, 20-30 parts of cinnamon oil.Medicine oil of the invention has a wind dispelling cold dispelling, warming and activating meridian, promoting blood circulation and stopping pain, the effect to strengthen muscles and bones, and to chronic lumbar strain, Disc herniation, sciatica, articular degeneration initial stage, spur, cold disease condenses the diseases such as the lump to be formed significant curative effect.

Description

A kind of wind-damp dispelling Chinese medicine medicine oil and preparation method thereof
Technical field
The present invention relates to rheumatism field of traditional Chinese medicine preparations, and in particular to a kind of wind-damp dispelling Chinese medicine medicine oil and preparation method thereof.
Background technique
It is the most common with rheumatism in chronic rheumatism patient, it is de- in pathologically chronic lumbar strain, interverbebral disc Out, sciatica, articular degeneration, spur, cold disease condense the lump to be formed, and bring not to people's lives after the onset Just.Currently, existing traditional Chinese medicinal ointment or the poor defect of the generally existing drug effect of medicine oil in the market, and to the utilization rate of Chinese medicine It is relatively low.
Summary of the invention
To solve the above problems, the present invention provides a kind of wind-damp dispelling Chinese medicine medicine oils and preparation method thereof.
To achieve the above object, the technical scheme adopted by the invention is as follows:
A kind of wind-damp dispelling Chinese medicine medicine oil, is prepared by the raw material of following parts by weight:
10-20 parts of Radix Notoginseng, 10-20 parts of safflower, 5-15 parts of radix saposhnikoviae, 5-15 parts of excrementum pteropi, 10-15 parts of lopseed, the root of Chinese clematis 10-20 parts, 5-10 parts of Rhizoma Et Radix Notopterygii, 5-15 parts of caulis trachelospermi, 5-7 parts of frutus cnidii, 3-5 parts of Chinese prickly ash, 5-10 parts of lycopodium calvatum, ramulus cinnamomi 10-15 Part, 3-6 parts of ginger splices, 1-3 parts of peppermint, 20-30 parts of cinnamon oil.
Preferably, it is prepared by the raw material of following parts by weight:
10 parts of Radix Notoginseng, 10 parts of safflower, windproof 5 parts, 5 parts of excrementum pteropi, 10 parts of lopseed, 10 parts of the root of Chinese clematis, 5 parts of Rhizoma Et Radix Notopterygii, network 5 parts of stone rattan, 5 parts of frutus cnidii, 3 parts of Chinese prickly ash, 5 parts of lycopodium calvatum, 10 parts of ramulus cinnamomi, 3 parts of ginger splices, 1 part of peppermint, 20 parts of cinnamon oil.
Preferably, the raw material of part is prepared:
20 parts of Radix Notoginseng, 20 parts of safflower, radix saposhnikoviae 15 parts, 15 parts of excrementum pteropi, 15 parts of lopseed, 20 parts of the root of Chinese clematis, 10 parts of Rhizoma Et Radix Notopterygii, 15 parts of caulis trachelospermi, 7 parts of frutus cnidii, 5 parts of Chinese prickly ash, 10 parts of lycopodium calvatum, 15 parts of ramulus cinnamomi, 6 parts of ginger splices, 3 parts of peppermint, 30 parts of cinnamon oil.
Preferably, it is prepared by the raw material of following parts by weight:
15 parts of Radix Notoginseng, 15 parts of safflower, windproof 10 parts, 10 parts of excrementum pteropi, 12.5 parts of lopseed, 15 parts of the root of Chinese clematis, Rhizoma Et Radix Notopterygii 7.5 Part, 10 parts of caulis trachelospermi, 6 parts of frutus cnidii, 4 parts of Chinese prickly ash, 7.5 parts of lycopodium calvatum, 12.5 parts of ramulus cinnamomi, 4.5 parts of ginger splices, 2 parts of peppermint, cortex cinnamomi 25 parts of oil.
The present invention also provides a kind of preparation methods of wind-damp dispelling Chinese medicine medicine oil, include the following steps:
S1, each component is weighed by above-mentioned formula;
S2, by weighed Radix Notoginseng, safflower, radix saposhnikoviae, excrementum pteropi, lopseed, the root of Chinese clematis, Rhizoma Et Radix Notopterygii, caulis trachelospermi, frutus cnidii, flower After green pepper, lycopodium calvatum, ramulus cinnamomi, ginger splices clean dry to moisture content are 3wt%, after freezing 3~5h of embrittlement, in 30~40 DEG C of conditions Under, supersonic wave wall breaking processing is carried out, powder is obtained;
S3, supercritical carbon dioxide extracting, extracting pressure 30MPa, level-one separating pressure will be carried out after resulting powder For 8.5MPa, the second-order separation pressure is 6.5MPa, and extraction time 2h, extraction temperature is 15~45 DEG C, collects residue and one Extract in grade and the second-order separation kettle;
The ethanol solution that volumetric concentration is 75~85% is added into residue according to the ratio of 1g: 10~20mL, in 60 DEG C Lower ultrasonic 1~2h, filtering, merging filtrate, concentration and recovery ethyl alcohol obtain extracting solution;
S4, resulting extract, extracting solution and weighed cinnamon oil are mixed evenly after to get medicine oil.
The invention has the following advantages:
Medicine oil of the invention has wind dispelling cold dispelling, warming and activating meridian, promoting blood circulation and stopping pain, the effect to strengthen muscles and bones, to chronic lumbar Strain, Disc herniation, sciatica, articular degeneration initial stage, spur, cold disease condense the diseases such as the lump to be formed have it is aobvious Write curative effect.
Specific embodiment
The present invention is described in detail combined with specific embodiments below.Following embodiment will be helpful to the technology of this field Personnel further understand the present invention, but the invention is not limited in any way.It should be pointed out that the ordinary skill of this field For personnel, without departing from the inventive concept of the premise, various modifications and improvements can be made.These belong to the present invention Protection scope.
Embodiment 1
A kind of preparation method of wind-damp dispelling Chinese medicine medicine oil, includes the following steps:
S1, it weighs by weight: 10 parts of Radix Notoginseng, 10 parts of safflower, windproof 5 parts, 5 parts of excrementum pteropi, 10 parts of lopseed, the root of Chinese clematis 10 parts, 5 parts of Rhizoma Et Radix Notopterygii, 5 parts of caulis trachelospermi, 5 parts of frutus cnidii, 3 parts of Chinese prickly ash, 5 parts of lycopodium calvatum, 10 parts of ramulus cinnamomi, 3 parts of ginger splices, 1 part of peppermint, 20 parts of cinnamon oil;
S2, by weighed Radix Notoginseng, safflower, radix saposhnikoviae, excrementum pteropi, lopseed, the root of Chinese clematis, Rhizoma Et Radix Notopterygii, caulis trachelospermi, frutus cnidii, flower After green pepper, lycopodium calvatum, ramulus cinnamomi, ginger splices clean dry to moisture content are 3wt%, after freezing 3~5h of embrittlement, in 30~40 DEG C of conditions Under, supersonic wave wall breaking processing is carried out, powder is obtained;
S3, supercritical carbon dioxide extracting, extracting pressure 30MPa, level-one separating pressure will be carried out after resulting powder For 8.5MPa, the second-order separation pressure is 6.5MPa, and extraction time 2h, extraction temperature is 15~45 DEG C, collects residue and one Extract in grade and the second-order separation kettle;
The ethanol solution that volumetric concentration is 75~85% is added into residue according to the ratio of 1g: 10~20mL, in 60 DEG C Lower ultrasonic 1~2h, filtering, merging filtrate, concentration and recovery ethyl alcohol obtain extracting solution;
S4, resulting extract, extracting solution and weighed cinnamon oil are mixed evenly after to get medicine oil.
Embodiment 2
A kind of preparation method of wind-damp dispelling Chinese medicine medicine oil, includes the following steps:
S1, it weighs by weight: 20 parts of Radix Notoginseng, 20 parts of safflower, windproof 15 parts, 15 parts of excrementum pteropi, 15 parts of lopseed, Wheeling Celestial 20 parts, 10 parts of Rhizoma Et Radix Notopterygii, 15 parts of caulis trachelospermi, 7 parts of frutus cnidii, 5 parts of Chinese prickly ash, 10 parts of lycopodium calvatum, 15 parts of ramulus cinnamomi, 6 parts of ginger splices, peppermint 3 parts, 30 parts of cinnamon oil;
S2, by weighed Radix Notoginseng, safflower, radix saposhnikoviae, excrementum pteropi, lopseed, the root of Chinese clematis, Rhizoma Et Radix Notopterygii, caulis trachelospermi, frutus cnidii, flower After green pepper, lycopodium calvatum, ramulus cinnamomi, ginger splices clean dry to moisture content are 3wt%, after freezing 3~5h of embrittlement, in 30~40 DEG C of conditions Under, supersonic wave wall breaking processing is carried out, powder is obtained;
S3, supercritical carbon dioxide extracting, extracting pressure 30MPa, level-one separating pressure will be carried out after resulting powder For 8.5MPa, the second-order separation pressure is 6.5MPa, and extraction time 2h, extraction temperature is 15~45 DEG C, collects residue and one Extract in grade and the second-order separation kettle;
The ethanol solution that volumetric concentration is 75~85% is added into residue according to the ratio of 1g: 10~20mL, in 60 DEG C Lower ultrasonic 1~2h, filtering, merging filtrate, concentration and recovery ethyl alcohol obtain extracting solution;
S4, resulting extract, extracting solution and weighed cinnamon oil are mixed evenly after to get medicine oil.
Embodiment 3
A kind of preparation method of wind-damp dispelling Chinese medicine medicine oil, includes the following steps:
S1, it weighs by weight: 15 parts of Radix Notoginseng, 15 parts of safflower, windproof 10 parts, 10 parts of excrementum pteropi, 12.5 parts of lopseed, prestige 15 parts of medicine xiaolingxian, 7.5 parts of Rhizoma Et Radix Notopterygii, 10 parts of caulis trachelospermi, 6 parts of frutus cnidii, 4 parts of Chinese prickly ash, 7.5 parts of lycopodium calvatum, 12.5 parts of ramulus cinnamomi, ginger splices 4.5 parts, 2 parts of peppermint, 25 parts of cinnamon oil;
S2, by weighed Radix Notoginseng, safflower, radix saposhnikoviae, excrementum pteropi, lopseed, the root of Chinese clematis, Rhizoma Et Radix Notopterygii, caulis trachelospermi, frutus cnidii, flower After green pepper, lycopodium calvatum, ramulus cinnamomi, ginger splices clean dry to moisture content are 3wt%, after freezing 3~5h of embrittlement, in 30~40 DEG C of conditions Under, supersonic wave wall breaking processing is carried out, powder is obtained;
S3, supercritical carbon dioxide extracting, extracting pressure 30MPa, level-one separating pressure will be carried out after resulting powder For 8.5MPa, the second-order separation pressure is 6.5MPa, and extraction time 2h, extraction temperature is 15~45 DEG C, collects residue and one Extract in grade and the second-order separation kettle;
The ethanol solution that volumetric concentration is 75~85% is added into residue according to the ratio of 1g: 10~20mL, in 60 DEG C Lower ultrasonic 1~2h, filtering, merging filtrate, concentration and recovery ethyl alcohol obtain extracting solution;
S4, resulting extract, extracting solution and weighed cinnamon oil are mixed evenly after to get medicine oil.
Specific embodiments of the present invention are described above.It is to be appreciated that the invention is not limited to above-mentioned Particular implementation, those skilled in the art can make a variety of changes or modify within the scope of the claims, this not shadow Ring substantive content of the invention.In the absence of conflict, the feature in embodiments herein and embodiment can any phase Mutually combination.

Claims (5)

1. a kind of wind-damp dispelling Chinese medicine medicine oil, it is characterised in that: be prepared by the raw material of following parts by weight:
10-20 parts of Radix Notoginseng, 10-20 parts of safflower, 5-15 parts of radix saposhnikoviae, 5-15 parts of excrementum pteropi, 10-15 parts of lopseed, root of Chinese clematis 10-20 Part, 5-10 parts of Rhizoma Et Radix Notopterygii, 5-15 parts of caulis trachelospermi, 5-7 parts of frutus cnidii, 3-5 parts of Chinese prickly ash, 5-10 parts of lycopodium calvatum, 10-15 parts of ramulus cinnamomi, ginger 3-6 parts of piece, 1-3 parts of peppermint, 20-30 parts of cinnamon oil.
2. a kind of wind-damp dispelling Chinese medicine medicine oil as described in claim 1, it is characterised in that: by the raw material preparation of following parts by weight At:
10 parts of Radix Notoginseng, 10 parts of safflower, windproof 5 parts, 5 parts of excrementum pteropi, 10 parts of lopseed, 10 parts of the root of Chinese clematis, 5 parts of Rhizoma Et Radix Notopterygii, caulis trachelospermi 5 Part, 5 parts of frutus cnidii, 3 parts of Chinese prickly ash, 5 parts of lycopodium calvatum, 10 parts of ramulus cinnamomi, 3 parts of ginger splices, 1 part of peppermint, 20 parts of cinnamon oil.
3. a kind of wind-damp dispelling Chinese medicine medicine oil as described in claim 1, it is characterised in that: by the raw material preparation of following parts by weight At:
20 parts of Radix Notoginseng, 20 parts of safflower, windproof 15 parts, 15 parts of excrementum pteropi, 15 parts of lopseed, 20 parts of the root of Chinese clematis, 10 parts of Rhizoma Et Radix Notopterygii, trachelospermum jasminoide 15 parts of rattan, 7 parts of frutus cnidii, 5 parts of Chinese prickly ash, 10 parts of lycopodium calvatum, 15 parts of ramulus cinnamomi, 6 parts of ginger splices, 3 parts of peppermint, 30 parts of cinnamon oil.
4. a kind of wind-damp dispelling Chinese medicine medicine oil as described in claim 1, it is characterised in that: by the raw material preparation of following parts by weight At:
15 parts of Radix Notoginseng, 15 parts of safflower, radix saposhnikoviae 10 parts, 10 parts of excrementum pteropi, 12.5 parts of lopseed, 15 parts of the root of Chinese clematis, 7.5 parts of Rhizoma Et Radix Notopterygii, 10 parts of caulis trachelospermi, 6 parts of frutus cnidii, 4 parts of Chinese prickly ash, 7.5 parts of lycopodium calvatum, 12.5 parts of ramulus cinnamomi, 4.5 parts of ginger splices, 2 parts of peppermint, cinnamon oil 25 parts.
5. a kind of preparation method of wind-damp dispelling Chinese medicine medicine oil, characterized by the following steps:
S1, each component is weighed by the described in any item formulas of claim 1-4;
S2, by weighed Radix Notoginseng, safflower, radix saposhnikoviae, excrementum pteropi, lopseed, the root of Chinese clematis, Rhizoma Et Radix Notopterygii, caulis trachelospermi, frutus cnidii, Chinese prickly ash, stretch After muscle grass, ramulus cinnamomi, ginger splices clean dry to moisture content are 3wt%, after freezing 3~5h of embrittlement, under the conditions of 30~40 DEG C, into The processing of row supersonic wave wall breaking, obtains powder;
S3, supercritical carbon dioxide extracting, extracting pressure 30MPa will be carried out after resulting powder, level-one separating pressure is 8.5MPa, the second-order separation pressure are 6.5MPa, and extraction time 2h, extraction temperature is 15~45 DEG C, collects residue and level-one With the extract in the second-order separation kettle;
The ethanol solution that volumetric concentration is 75~85% is added into residue according to the ratio of 1g: 10~20mL, surpasses at 60 DEG C 1~2h of sound, filtering, merging filtrate, concentration and recovery ethyl alcohol obtain extracting solution;
S4, resulting extract, extracting solution and weighed cinnamon oil are mixed evenly after to get medicine oil.
CN201811337342.7A 2018-11-07 2018-11-07 A kind of wind-damp dispelling Chinese medicine medicine oil and preparation method thereof Pending CN109260438A (en)

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Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060110468A1 (en) * 2004-11-24 2006-05-25 Liang Liu Herbal formulations for arthritis
CN101143166A (en) * 2006-09-13 2008-03-19 广东中大南海海洋生物技术工程中心有限公司 Medicine for swelling and relieving pain and its preparation method and application
CN107998192A (en) * 2017-12-01 2018-05-08 浙江海洋大学 Traditional Chinese medicine plaster based on aethiops vegetabilis fiber treatment rheumatic disease and preparation method thereof

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060110468A1 (en) * 2004-11-24 2006-05-25 Liang Liu Herbal formulations for arthritis
CN101143166A (en) * 2006-09-13 2008-03-19 广东中大南海海洋生物技术工程中心有限公司 Medicine for swelling and relieving pain and its preparation method and application
CN107998192A (en) * 2017-12-01 2018-05-08 浙江海洋大学 Traditional Chinese medicine plaster based on aethiops vegetabilis fiber treatment rheumatic disease and preparation method thereof

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
李志铭 主编: "《李志铭经验妙方》", 31 August 2013 *

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