CN109224072B - Antiviral oral liquid for enhancing immunity and preparation method thereof - Google Patents
Antiviral oral liquid for enhancing immunity and preparation method thereof Download PDFInfo
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- CN109224072B CN109224072B CN201811384561.0A CN201811384561A CN109224072B CN 109224072 B CN109224072 B CN 109224072B CN 201811384561 A CN201811384561 A CN 201811384561A CN 109224072 B CN109224072 B CN 109224072B
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Abstract
The invention discloses an antiviral oral liquid for enhancing immunity, which comprises the following raw materials in parts by weight: 8-10 parts of isatis root, 3-5 parts of forsythia, 2-3 parts of patchouli, 2.5-4 parts of grassleaf sweelflag rhizome, 1-2 parts of gypsum, 1.5-2.5 parts of turmeric root-tuber, 3-6 parts of rhizoma anemarrhenae, 1-3 parts of reed rhizome, 4-5 parts of rehmannia root, 3-3.5 parts of cane sugar and 2-4 parts of honey; according to the antiviral oral liquid for enhancing immunity and the preparation method thereof, the bottle body fixing frame is arranged on the conveying belt of the far infrared sterilization dryer, so that an oral liquid bottle can be well fixed, the oral liquid bottle is effectively prevented from being difficultly treated by rolling in the process of drying the oral liquid bottle, the collection box is arranged to facilitate the collection of the oral liquid bottle, the sterilization box can be conveniently opened by arranging the butt joint assembly, the inside of the sterilization box is conveniently maintained, the gamma globulin is added into the oral liquid, the antiviral effect can be achieved after a user drinks the oral liquid, and the purpose of enhancing immunity can be achieved.
Description
Technical Field
The invention belongs to the technical field of oral liquid preparation, and particularly relates to an antiviral oral liquid, and more particularly relates to an antiviral oral liquid for enhancing immunity and a preparation method thereof.
Background
The antiviral oral liquid is a Chinese patent medicine, and comprises the components of isatis root, gypsum, aloe, radix rehmanniae, radix curcumae, rhizoma anemarrhenae, rhizoma acori graminei, pogostemon cablin and fructus forsythiae, and is applicable to the diseases of cold, epidemic febrile disease, fever, upper respiratory infection, influenza and mumps virus infection. Although the medicinal components are safe and nontoxic, the medicinal components are not health care products recommended to be taken daily, but are antiviral medicaments, 90 percent of common cold is caused by viruses, and influenza is caused by influenza viruses, so that the diseases are all applicable to antiviral oral liquid, and the optimal taking time of the antiviral oral liquid is that the antiviral oral liquid is taken within 24 hours when symptoms appear at the beginning of cold and influenza;
present antiviral oral liquid has certain drawback at preparation and in-process of using, present antiviral oral liquid is at the manufacturing process, the oral liquid bottle is inconvenient to be fixed and collect when carrying out the drying to the oral liquid bottle to the far infrared desiccator that disinfects, the oral liquid bottle appears the condition of rolling everywhere easily when the drying, and the case that disinfects of far infrared desiccator that disinfects all is the integration basically, it is more troublesome when dismantling the maintenance, furthermore, most antiviral oral liquid only has antiviral effect basically, can not strengthen immunity after the taking, the effect is more single, it is comparatively troublesome.
Disclosure of Invention
In order to overcome the technical problems, the invention aims to provide an antiviral oral liquid for enhancing immunity and a preparation method thereof, wherein a bottle body fixing frame is arranged on a conveying belt of a far infrared sterilization dryer, and a fixing groove on a movable block on one side of the bottle body fixing frame can be used for placing an oral liquid bottle, so that the oral liquid bottle can be well fixed, the situation that the oral liquid bottle is not easy to handle due to rolling in the process of drying the oral liquid bottle is effectively prevented, and a collecting box is arranged, so that the oral liquid bottle is convenient to store after the oral liquid bottle is treated; by arranging the butt joint assembly, the upper conjunction block and the lower conjunction block on the butt joint assembly can be separated by only adjusting the fixed handle to the horizontal direction and pulling the inside of the sterilization box, so that the sterilization box can be separated, the sterilization box can be conveniently opened, and the inside of the sterilization box can be conveniently maintained; through adding gamma globulin in the filtrate after the oral liquid is filtered and concentrated, the antiviral effect can be achieved after a user drinks the oral liquid, and the purpose of increasing immunity can be achieved, so that the effect of the oral liquid is better, and the effect is more obvious.
The purpose of the invention can be realized by the following technical scheme:
an antiviral oral liquid for enhancing immunity comprises the following raw materials in parts by weight: 8-10 parts of isatis root, 3-5 parts of forsythia, 2-3 parts of patchouli, 2.5-4 parts of grassleaf sweelflag rhizome, 1-2 parts of gypsum, 1.5-2.5 parts of turmeric root-tuber, 3-6 parts of rhizoma anemarrhenae, 1-3 parts of reed rhizome, 4-5 parts of rehmannia root, 3-3.5 parts of cane sugar and 2-4 parts of honey, and the oral liquid is prepared by the following steps:
the method comprises the following steps: taking the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root in parts by weight, putting the decoction pieces into an extraction tank, adding purified water, decocting twice in the extraction tank, collecting volatile oil, clathrating the volatile oil with hydroxypropyl beta cyclodextrin, and putting the collected volatile oil into a volatile oil storage tank;
step two: filtering the decocted liquid medicine for three times by using a straight-tube extraction tank, combining the filtered filtrates, concentrating the filtrate by using the straight-tube extraction tank, and concentrating the filtrate to a proper proportion;
step three: adding 88% ethanol into the concentrated solution to precipitate the concentrated solution, wherein the ethanol content in the concentrated solution is 70-75%, standing for 12h, filtering the filtrate with gauze, and collecting the filtrate in a liquid storage tank;
step four: heating the filtrate collected in the liquid storage tank, controlling the temperature in the liquid storage tank to be 80 ℃, evaporating ethanol in the filtrate, and collecting the filtrate;
step five: adding the added volatile oil into the filtrate, adding 3 parts of sucrose and 2 parts of honey, adding 0.5 part of orange essence, 0.5 part of sodium cyclamate and 4 parts of gamma globulin, adjusting the pH value of the filtrate by using 15% sodium hydroxide solution, and filtering the filtrate by using gauze;
step six: the method comprises the steps of cleaning an oral liquid bottle by using a vertical ultrasonic bottle washer, placing the cleaned oral liquid bottle into a far infrared sterilization dryer for drying and sterilization, placing the oral liquid bottle and filtrate into a liquid filling roll for filling and packaging and sealing, placing the packaged oral liquid into an ampoule leakage detection sterilization cabinet for leakage detection, and placing the oral liquid subjected to leakage detection into an ampoule sterilizer for sterilization.
A preparation method of antiviral oral liquid for enhancing immunity comprises the following specific steps:
the method comprises the following steps: taking the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root in parts by weight, putting the decoction pieces into an extraction tank, adding purified water, decocting twice in the extraction tank, collecting volatile oil, clathrating the volatile oil with hydroxypropyl beta cyclodextrin, and putting the collected volatile oil into a volatile oil storage tank;
step two: filtering the decocted liquid medicine for three times by using a straight-tube extraction tank, combining the filtered filtrates, concentrating the filtrate by using the straight-tube extraction tank, and concentrating the filtrate to a proper proportion;
step three: adding 88% ethanol into the concentrated solution to precipitate the concentrated solution, wherein the ethanol content in the concentrated solution is 70-75%, standing for 12h, filtering the filtrate with gauze, and collecting the filtrate in a liquid storage tank;
step four: heating the filtrate collected in the liquid storage tank, controlling the temperature in the liquid storage tank to be 80 ℃, evaporating ethanol in the filtrate, and collecting the filtrate;
step five: adding the added volatile oil into the filtrate, adding 3 parts of sucrose and 2 parts of honey, adding 0.5 part of orange essence, 0.5 part of sodium cyclamate and 4 parts of gamma globulin, adjusting the pH value of the filtrate by using 15% sodium hydroxide solution, and filtering the filtrate by using gauze;
step six: the method comprises the steps of cleaning an oral liquid bottle by using a vertical ultrasonic bottle washer, placing the cleaned oral liquid bottle into a far infrared sterilization dryer for drying and sterilization, placing the oral liquid bottle and filtrate into a liquid filling roll for filling and packaging and sealing, placing the packaged oral liquid into an ampoule leakage detection sterilization cabinet for leakage detection, and placing the oral liquid subjected to leakage detection into an ampoule sterilizer for sterilization.
As a further scheme of the invention: the time for decocting twice in the first step is respectively as follows: the ratio of the isatis root, the weeping forsythia, the patchouli, the grassleaf sweelflag rhizome, the gypsum, the turmeric root-tuber, the common anemarrhena rhizome, the reed rhizome and the rehmannia root to the purified water is 1:1.5 for the first time and the second time, wherein the ratio of the isatis root, the weeping forsythia, the patchouli, the grassleaf sweelflag rhizome, the gypsum, the turmeric root-tuber, the common anemarrhena rhizome, the reed rhizome and the rehmannia root are 1: 1.5.
As a further scheme of the invention: the cleaning time of the vertical ultrasonic bottle washing machine in the sixth step is 0.5h, and the sterilization time of the ampoule leakage detection sterilization cabinet is 0.2 h;
as a further scheme of the invention: the far infrared sterilization dryer comprises two groups of support frames, wherein the two groups of support frames are arranged in parallel, a motor box is mounted at the inner bottom end of each support frame, a mounting frame is mounted on the upper surfaces of the two groups of support frames, a collecting box is arranged between the two groups of support frames by the upper end of one side, a soft cushion block is arranged at the inner bottom end of the collecting box, a sterilization box is mounted on the upper surface of each mounting frame, an access door is arranged on the front surface of the sterilization box, butt joint assemblies are arranged on the periphery of the outer side of the sterilization box, a power box and an exhaust port are mounted on the upper surface of the sterilization box, a conveyor belt is arranged between the two groups of mounting frames by the lower side of the sterilization box, and a plurality of groups of bottle body fixing frames are arranged on the outer surface of the conveyor belt;
an infrared emitter is arranged at the upper end inside the sterilization box, a radiation lamp tube is connected to the lower surface of the infrared emitter, and a reflecting convex mirror is arranged on one side inside the sterilization box;
a movable block is arranged on one side of the bottle body fixing frame, a plurality of groups of fixing grooves are formed in one side of the movable block, and a rotating shaft is arranged between the movable block and the bottle body fixing frame;
the butt joint assembly comprises an upper conjunction block and a lower conjunction block, a connection groove is formed in the lower surface of the upper conjunction block, and a convex block is arranged on the upper surface of the lower conjunction block.
As a further scheme of the invention: the motor box is internally provided with a motor which is a servo motor, and a belt is arranged between the motor and the conveyor belt and is in transmission connection with the conveyor belt.
As a further scheme of the invention: the front surface of the sterilization box is provided with a fixed handle by an access door, the position of the fixed handle corresponds to the position of the butt joint assembly in the front and back directions, one end of the fixed handle is movably connected with the front surface of the sterilization box, and the other end of the fixed handle is not in contact with the front surface of the sterilization box.
As a further scheme of the invention: the inner wall of a plurality of groups the fixed slot all is provided with anti-skidding line, and a plurality of groups fixed slot is horizontal word arrangement.
The invention has the beneficial effects that:
1. according to the invention, the bottle body fixing frame is arranged on the conveying belt of the far infrared sterilization dryer in the preparation process of the oral liquid, and the fixing groove on the movable block at one side of the bottle body fixing frame can be used for placing the oral liquid bottle, so that the oral liquid bottle can be well fixed, the situation that the oral liquid bottle is difficult to handle due to rolling in the process of drying the oral liquid bottle is effectively prevented, and the oral liquid bottle is convenient to store after the oral liquid bottle is treated;
2. according to the invention, the butt joint component is arranged on the far infrared sterilization dryer in the preparation process of the oral liquid, when the sterilization box needs to be disassembled, the sterilization box can be separated by only adjusting the fixed handle to the horizontal direction and pulling the inside of the sterilization box, so that the upper fit block and the lower fit block on the butt joint component can be separated, the sterilization box can be conveniently opened, and the inside of the sterilization box can be conveniently maintained;
3. according to the invention, the gamma globulin is added into the filtrate obtained after the oral liquid is filtered and concentrated in the preparation process of the oral liquid, so that the antiviral effect can be achieved after a user drinks the oral liquid, the aim of enhancing the immunity can be achieved, the effect of the oral liquid is better, and the effect is more obvious.
Drawings
The invention will be further described with reference to the accompanying drawings.
Fig. 1 is a schematic view of the overall structure of the far infrared sterilizing dryer of the present invention.
Fig. 2 is an internal structure view of a sterilization box of the far infrared sterilization dryer of the present invention.
Fig. 3 is a schematic structural view of a bottle body fixing frame of the far infrared sterilizing dryer of the present invention.
Fig. 4 is a sectional view of the docking assembly of the far infrared sterilizing dryer of the present invention.
In the figure 1, a support frame; 2. a motor case; 3. a mounting frame; 4. a collection box; 5. a soft cushion block; 6. a sterilization box; 7. an access door; 8. a docking assembly; 9. a power supply box; 10. an exhaust port; 11. a conveyor belt; 12. a bottle body fixing frame; 13. an infrared emitter; 14. an emission lamp tube; 15. a reflective convex mirror; 16. a movable block; 17. fixing grooves; 18. a rotating shaft; 19. fitting blocks are arranged; 20. a lower conjunction block; 21. a joining groove; 22. and (4) a bump.
Detailed Description
The technical solutions in the embodiments of the present invention will be clearly and completely described below with reference to the embodiments of the present invention, and it is obvious that the described embodiments are only a part of the embodiments of the present invention, and not all of the embodiments. All other embodiments, which can be derived by a person skilled in the art from the embodiments given herein without making any creative effort, shall fall within the protection scope of the present invention.
As shown in figures 1-4, an antiviral oral liquid for enhancing immunity comprises the following raw materials in parts by weight: 8-10 parts of isatis root, 3-5 parts of forsythia, 2-3 parts of patchouli, 2.5-4 parts of grassleaf sweelflag rhizome, 1-2 parts of gypsum, 1.5-2.5 parts of turmeric root-tuber, 3-6 parts of rhizoma anemarrhenae, 1-3 parts of reed rhizome, 4-5 parts of rehmannia root, 3-3.5 parts of cane sugar and 2-4 parts of honey, and the oral liquid is prepared by the following steps:
the method comprises the following steps: taking the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root in parts by weight, putting the decoction pieces into an extraction tank, adding purified water, decocting twice in the extraction tank, collecting volatile oil, clathrating the volatile oil with hydroxypropyl beta cyclodextrin, and putting the collected volatile oil into a volatile oil storage tank;
step two: filtering the decocted liquid medicine for three times by using a straight-tube extraction tank, combining the filtered filtrates, concentrating the filtrate by using the straight-tube extraction tank, and concentrating the filtrate to a proper proportion;
step three: adding 88% ethanol into the concentrated solution to precipitate the concentrated solution, wherein the ethanol content in the concentrated solution is 70-75%, standing for 12h, filtering the filtrate with gauze, and collecting the filtrate in a liquid storage tank;
step four: heating the filtrate collected in the liquid storage tank, controlling the temperature in the liquid storage tank to be 80 ℃, evaporating ethanol in the filtrate, and collecting the filtrate;
step five: adding the added volatile oil into the filtrate, adding 3 parts of sucrose and 2 parts of honey, adding 0.5 part of orange essence, 0.5 part of sodium cyclamate and 4 parts of gamma globulin, adjusting the pH value of the filtrate by using 15% sodium hydroxide solution, and filtering the filtrate by using gauze;
step six: the method comprises the steps of cleaning an oral liquid bottle by using a vertical ultrasonic bottle washer, placing the cleaned oral liquid bottle into a far infrared sterilization dryer for drying and sterilization, placing the oral liquid bottle and filtrate into a liquid filling roll for filling and packaging and sealing, placing the packaged oral liquid into an ampoule leakage detection sterilization cabinet for leakage detection, and placing the oral liquid subjected to leakage detection into an ampoule sterilizer for sterilization.
A preparation method of antiviral oral liquid for enhancing immunity comprises the following specific steps:
the method comprises the following steps: taking the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root in parts by weight, putting the decoction pieces into an extraction tank, adding purified water, decocting twice in the extraction tank, collecting volatile oil, clathrating the volatile oil with hydroxypropyl beta cyclodextrin, and putting the collected volatile oil into a volatile oil storage tank;
step two: filtering the decocted liquid medicine for three times by using a straight-tube extraction tank, combining the filtered filtrates, concentrating the filtrate by using the straight-tube extraction tank, and concentrating the filtrate to a proper proportion;
step three: adding 88% ethanol into the concentrated solution to precipitate the concentrated solution, wherein the ethanol content in the concentrated solution is 70-75%, standing for 12h, filtering the filtrate with gauze, and collecting the filtrate in a liquid storage tank;
step four: heating the filtrate collected in the liquid storage tank, controlling the temperature in the liquid storage tank to be 80 ℃, evaporating ethanol in the filtrate, and collecting the filtrate;
step five: adding the added volatile oil into the filtrate, adding 3 parts of sucrose and 2 parts of honey, adding 0.5 part of orange essence, 0.5 part of sodium cyclamate and 4 parts of gamma globulin, adjusting the pH value of the filtrate by using 15% sodium hydroxide solution, and filtering the filtrate by using gauze;
step six: the method comprises the steps of cleaning an oral liquid bottle by using a vertical ultrasonic bottle washer, placing the cleaned oral liquid bottle into a far infrared sterilization dryer for drying and sterilization, placing the oral liquid bottle and filtrate into a liquid filling roll for filling and packaging and sealing, placing the packaged oral liquid into an ampoule leakage detection sterilization cabinet for leakage detection, and placing the oral liquid subjected to leakage detection into an ampoule sterilizer for sterilization.
As a further scheme of the invention: the time for decocting twice in the first step is respectively as follows: the ratio of the isatis root, the weeping forsythia, the patchouli, the grassleaf sweelflag rhizome, the gypsum, the turmeric root-tuber, the common anemarrhena rhizome, the reed rhizome and the rehmannia root to the purified water is 1:1.5 for the first time and the second time, wherein the ratio of the isatis root, the weeping forsythia, the patchouli, the grassleaf sweelflag rhizome, the gypsum, the turmeric root-tuber, the common anemarrhena rhizome, the reed rhizome and the rehmannia root are 1: 1.5.
As a further scheme of the invention: the cleaning time of the vertical ultrasonic bottle washing machine in the sixth step is 0.5h, and the sterilization time of the ampoule leakage detection sterilization cabinet is 0.2 h;
as a further scheme of the invention: the far infrared sterilization dryer in the sixth step comprises two groups of support frames 1, wherein the two groups of support frames 1 are arranged in parallel, a motor box 2 is installed at the inner bottom end of each support frame 1, an installation frame 3 is installed on the upper surface of each support frame 1, a collection box 4 is arranged between the two groups of support frames 1 close to the upper end of one side, a soft cushion block 5 is arranged at the inner bottom end of the collection box 4, a sterilization box 6 is installed on the upper surface of each installation frame 3, an access door 7 is arranged on the front surface of the sterilization box 6, butt joint assemblies 8 are arranged on the periphery of the outer side of the sterilization box 6, a power supply box 9 and an exhaust port 10 are installed on the upper surface of the sterilization box 6, the power supply box 9 and the exhaust port 10 are arranged in a flat mode, a conveyor belt 11 is arranged between the two groups of installation frames 3 close to the lower side of the sterilization box 6, and a plurality of bottle body fixing frames 12 are arranged on the outer surface of the conveyor belt 11;
an infrared emitter 13 is arranged at the upper end inside the sterilization box 6, a radiation lamp tube 14 is connected to the lower surface of the infrared emitter 13, and a reflecting convex mirror 15 is arranged on one side inside the sterilization box 6;
a movable block 16 is arranged at one side of the bottle body fixing frame 12, a plurality of groups of fixed grooves 17 are arranged at one side of the movable block 16, and a rotating shaft 18 is arranged between the movable block 16 and the bottle body fixing frame 12;
the butt joint component 8 comprises an upper fitting block 19 and a lower fitting block 20, wherein the lower surface of the upper fitting block 19 is provided with a connecting groove 21, and the upper surface of the lower fitting block 20 is provided with a lug 22.
As a further scheme of the invention: a motor is arranged in the motor box 2, the motor is a servo motor, and a belt is arranged between the motor and the conveyor belt 11 for transmission connection.
As a further scheme of the invention: the front surface of case 6 that disinfects is provided with fixed handle by access door 7, and the position of fixed handle corresponds around with the position of butt joint subassembly 8, and the one end of fixed handle and the front surface swing joint of case 6 that disinfects, and the other end of fixed handle and the front surface contactless of case 6 that disinfects.
As a further scheme of the invention: the inner walls of the plurality of groups of fixing grooves 17 are all provided with anti-slip grains, and the plurality of groups of fixing grooves 17 are arranged in a horizontal line.
The working principle of the far infrared sterilization dryer is as follows: when in use, firstly, the cleaned oral liquid bottle is placed in a fixed groove 17 on a movable block 16 at one side of a bottle body fixing frame 12, a motor in a motor box 2 is started through a power box 9, the motor in the motor box 2 drives a conveyor belt 11 to transmit, the oral liquid bottle is conveyed into a sterilization box 6, an infrared emitter 13 and a radiation lamp tube 14 are started, the radiation lamp tube 14 emits infrared light, the infrared light generates a heat effect, so that the oral liquid bottle is dried and sterilized, the sterilized and dried oral liquid bottle is conveyed out from one end of the conveyor belt 11, during the conveying-out period, the movable block 16 at one side of the bottle body fixing frame 12 faces downwards, so that the oral liquid bottle falls into a collection box 4, a soft cushion block 5 can play a good buffering role to protect the oral liquid bottle, and a butt joint assembly 8 completes the fixation by utilizing the butt joint of a connecting groove 21 on an upper conjunction block 19 and a lug 22 on a lower conjunction block 20, utilize fixed handle to consolidate butt joint subassembly 8, when needing to dismantle case 6 that disinfects, only need to adjust fixed handle to the horizontal direction, the inside of case 6 that disinfects is disinfected in the pulling, can with the last piece 19 that agrees with on the butt joint subassembly 8 with agree with the piece 20 separation down, can part case 6 that disinfects, be convenient for clean and maintain the inside of case 6 that disinfects.
According to the invention, the bottle body fixing frame 12 is arranged on the conveying belt 11 of the far infrared sterilization dryer, and the fixing groove 17 on the movable block 16 on one side of the bottle body fixing frame 12 can be used for placing the oral liquid bottle, so that the oral liquid bottle can be well fixed, the situation that the oral liquid bottle is difficult to handle due to rolling in the process of drying the oral liquid bottle is effectively prevented, and the collecting box 4 is arranged, so that the oral liquid bottle can be conveniently stored after the oral liquid bottle is treated; by arranging the butt joint assembly 8, when the sterilization box 6 needs to be disassembled, the sterilization box 6 can be separated by only adjusting the fixed handle to the horizontal direction and pulling the inside of the sterilization box 6 to separate the upper fit block 19 and the lower fit block 20 on the butt joint assembly 8, so that the sterilization box 6 can be conveniently opened, and the inside of the sterilization box 6 can be conveniently maintained; through adding gamma globulin in the filtrate after the oral liquid is filtered and concentrated, the antiviral effect can be achieved after a user drinks the oral liquid, and the purpose of increasing immunity can be achieved, so that the effect of the oral liquid is better, and the effect is more obvious.
The foregoing is merely exemplary and illustrative of the present invention and various modifications, additions and substitutions may be made by those skilled in the art to the specific embodiments described without departing from the scope of the invention as defined in the following claims.
Claims (1)
1. A far infrared sterilization dryer for an antiviral oral liquid production process for enhancing immunity is characterized in that the antiviral oral liquid production process comprises the following raw materials in parts by weight: 8-10 parts of isatis root, 3-5 parts of forsythia, 2-3 parts of patchouli, 2.5-4 parts of grassleaf sweelflag rhizome, 1-2 parts of gypsum, 1.5-2.5 parts of turmeric root-tuber, 3-6 parts of rhizoma anemarrhenae, 1-3 parts of reed rhizome, 4-5 parts of rehmannia root, 3-3.5 parts of cane sugar and 2-4 parts of honey, and the oral liquid is prepared by the following steps:
the method comprises the following steps: taking the nine decoction pieces of isatis root, forsythia, patchouli, grassleaf sweelflag rhizome, gypsum, turmeric root-tuber, common anemarrhena rhizome, reed rhizome and rehmannia root in parts by weight, putting the decoction pieces into an extraction tank, adding purified water, decocting twice in the extraction tank, collecting volatile oil, clathrating the volatile oil with hydroxypropyl beta cyclodextrin, and putting the collected volatile oil into a volatile oil storage tank;
step two: filtering the decocted liquid medicine for three times by using a straight-tube extraction tank, combining the filtered filtrates, concentrating the filtrate by using the straight-tube extraction tank, and concentrating the filtrate to a proper proportion;
step three: adding 88% ethanol into the concentrated solution to precipitate the concentrated solution, wherein the ethanol content in the concentrated solution is 70-75%, standing for 12h, filtering the filtrate with gauze, and collecting the filtrate in a liquid storage tank;
step four: heating the filtrate collected in the liquid storage tank, controlling the temperature in the liquid storage tank to be 80 ℃, evaporating ethanol in the filtrate, and collecting the filtrate;
step five: adding the volatile oil into the filtrate, adding 3 parts of sucrose and 2 parts of honey, adding 0.5 part of orange essence, 0.5 part of sodium cyclamate and 4 parts of gamma globulin, adjusting the pH value of the filtrate by using 15% sodium hydroxide solution, and filtering the filtrate by using gauze;
step six: cleaning an oral liquid bottle by using a vertical ultrasonic bottle washer, then putting the cleaned oral liquid bottle into a far infrared sterilization dryer for drying and sterilization, putting the oral liquid bottle and filtrate into a liquid pad for filling and packaging and sealing, putting the packaged oral liquid into an ampoule leakage detection sterilization cabinet for leakage detection, and then putting the oral liquid subjected to leakage detection into an ampoule sterilizer for sterilization;
the far infrared sterilization dryer comprises two groups of supporting frames (1), wherein the two groups of supporting frames (1) are arranged in parallel, a motor box (2) is installed at the inner bottom end of each supporting frame (1), a mounting frame (3) is installed on the upper surface of each supporting frame (1), a collecting box (4) is arranged between the two groups of supporting frames (1) by means of the upper end of one side, a soft cushion block (5) is arranged at the inner bottom end of the collecting box (4), a sterilization box (6) is installed on the upper surface of each mounting frame (3), an access door (7) is arranged on the front surface of the sterilization box (6), butt joint assemblies (8) are arranged on the periphery of the outer side of the sterilization box (6), a power box (9) and an exhaust port (10) are installed on the upper surface of the sterilization box (6), the power box (9) and the exhaust port (10) are arranged in a flat mode, a conveyor belt (11) is arranged between the two groups of mounting frames (3) by means of the lower portion of the sterilization box (6), and the outer surface of the conveyor belt (11) is provided with a plurality of groups of bottle body fixing frames (12);
an infrared emitter (13) is arranged at the upper end of the inside of the sterilization box (6), the lower surface of the infrared emitter (13) is connected with a radiation lamp tube (14), and a reflecting convex mirror (15) is arranged on one side of the inside of the sterilization box (6);
a movable block (16) is arranged on one side of the bottle body fixing frame (12), a plurality of groups of fixing grooves (17) are formed in one side of the movable block (16), and a rotating shaft (18) is arranged between the movable block (16) and the bottle body fixing frame (12);
the butt joint assembly (8) comprises an upper conjunction block (19) and a lower conjunction block (20), the lower surface of the upper conjunction block (19) is provided with a connecting groove (21), and the upper surface of the lower conjunction block (20) is provided with a lug (22);
a motor is arranged in the motor box (2), the motor is a servo motor, and a belt is arranged between the motor and the conveyor belt (11) for transmission connection;
a fixed handle is arranged on the front surface of the sterilization box (6) close to the access door (7), the position of the fixed handle corresponds to the position of the butt joint component (8) in the front-back direction, one end of the fixed handle is movably connected with the front surface of the sterilization box (6), and the other end of the fixed handle is not in contact with the front surface of the sterilization box (6);
the inner walls of the plurality of groups of fixing grooves (17) are all provided with anti-skid grains, and the plurality of groups of fixing grooves (17) are arranged in a transverse straight line;
the time for decocting twice in the first step is respectively as follows: 1.8h for the first time and 1h for the second time, wherein the ratio of the isatis root, the weeping forsythia, the patchouli, the grassleaf sweelflag rhizome, the gypsum, the turmeric root-tuber, the common anemarrhena rhizome, the reed rhizome and the rehmannia root to the purified water is 1: 1.5;
and in the sixth step, the cleaning time of the vertical ultrasonic bottle washer is 0.5h, and the sterilization time of the ampoule leakage detection sterilization cabinet is 0.2 h.
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Denomination of invention: An antiviral oral solution for enhancing immunity and its preparation method Granted publication date: 20220503 Pledgee: Huainan Branch of Postal Savings Bank of China Pledgor: ANHUI DONGSHENG YOUBANG PHARMACEUTICAL CO.,LTD. Registration number: Y2024980001565 |
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