A kind of embryo transplanter for test-tube baby
Technical field
The present invention relates to gynaecology's family planning technical fields, are specifically related to a kind of embryo transplanter for test-tube baby.
Background technique:
" test-tube baby " often is " In vitro fertilization-embryo transplantation " (IVF-ET) China is civil.And in fact, body
Outer fertilization is a kind of special technology, is that ovum and sperm are all taken to allow the environment of their manual controls in vitro in vitro
Middle completion fertilization process, is then transplanted to body early embryo in the uterus of women, breeds in uterus as child.Using external
The baby that fertilization technique generates is known as test-tube baby, these children are also to grow up in the intrauterine of mother.It can be said that " test tube
Baby's technology " is equal to " in vitro fertilization.
In the treatment means of sterile disease, test-tube baby is to common are one of effect means.But in actual operation,
Since the tool used when embryo transfer is improper, thus cause cannot will to have cultivated successful embryo transfer enters inside uterus and
It leads to the failure.Especially for those parents with cervical canal deformity, embryo is sent into son by the cervical canal of deformity
It is just more difficult in uterine cavity, it selects most healthy embryo's injection and becomes pregnant into maternal uterine, do not allow because selecting healthy embryo
Easily, so the safety of embryo is critically important during injection, but embryo injection tool is too simple at present, safety coefficient compared with
It is low.
Summary of the invention
Against the above technical problems, the present invention provides a kind of embryo transplanters for test-tube baby.
The technical scheme is that
A kind of embryo transplanter for test-tube baby, including fixed link, support handle, hose, hollow shaft, pipeline one, pipeline
Two, the fixed link front end is connected with fixed disk by card slot, and channel is transversely provided in the middle part of fixed link, and the channel interior is set
There is syringe needle, rack rails one is equipped on the downside of the syringe needle rear end, lower end is rotatably connected to gear by rotating bar in the middle part of the fixed link
One, one engaged transmission of the gear one and rack rails, the fixed rod rear end is rotatably connected to wheel disc by the hollow shaft, described
Support asks the rear side upper end of handle to set embryo storehouse, is connected with embryo storehouse below the embryo storehouse being connected to below the rear end of fixed link
Propulsion device, is fixed with protection liquid storehouse below the embryo storehouse, and the protection liquid storehouse lower end, which is connected with protection liquid storehouse and promotes, to be filled
Set, front end is connected with gear two by rotating bar by support, gear two and protection liquid storehouse propulsion device engaged transmission, before the hose
End is laterally set on needle wall, is wrapped on wheel disc in the middle part of hose, hose end and hollow axis connection, embryo storehouse and hollow shaft
Between communicated by the pipeline one, pass through the pipeline two between the protection liquid storehouse and pipeline one and communicate.
Further, the fixed disk includes disk body, centre bore, sucker, connecting column, and the centre bore is located at the disk body
Center, there are four the connecting columns, and four connecting columns are uniformly distributed circumferentially in disk body front end, and there are four the suckers, four
A sucker is separately fixed at the front end of connecting column, reduces syringe needle in the intracorporal movement of parent by fixed disk.
Further, the wheel disk center is fixedly connected with hollow shaft, and the left end of hollow shaft passes through card slot and one turn of pipeline
The right end of dynamic connection, hollow shaft is equipped with limited post, and the right end of the limited post is fixedly connected with the inner wall of fixed link, limited post
Left end, by wheel disc by flexible pipe extending needle wall, avoids syringe needle from scratching embryo for limiting to hollow shaft.
Further, embryo storehouse propulsion device includes gasket one, pushing ram one, promotes button, the gasket
One is located at the lower end inside embryo storehouse, and one upper end of pushing ram is fixedly connected with gasket one, and one lower end of pushing ram passes through support
Outer wall is fixedly connected with the propulsion button, by promoting button that embryo storehouse internal liquid is quickly discharged.
Further, protection liquid storehouse propulsion device includes gasket two, pushing ram two, strip groove, sheet metal, rack rails
Two, the gasket two is located at the lower end inside protection liquid storehouse, and two upper end of pushing ram is fixedly connected with gasket two, described
Strip groove is located at the right side of gear two, and the rack rails two is located inside strip groove vertically, and the sheet metal is fixed on bar shaped vertically
The right side inner wall of slot, the lower end left side of pushing ram two pass through sheet metal lower end and are fixedly connected with two lower end of rack rails, pass through gear two
Accurately control the discharge rate of protection liquid.
Further, the embryo storehouse is for nutrient solution needed for storing embryo and embryonic development, the nutrient solution by with
Lower weight percent at being grouped as: 0.02% penicillin, compound amido acid injection 5%, human serum albumin 6.3%, chlorination
Potassium 1.2%, magnesium sulfate 0.5%, glucose 6%, gentamicin 0.08%, ethylenediamine tetra-acetic acid 3.2%, Sodium Pyruvate 2.2%,
Alanyl glutamine 1.5%, taurine 0.85%, D-glucitol 1.2%, calcium chloride 0.9%, sodium dihydrogen phosphate 0.5%, phosphorus
Acid dihydride potassium 0.7%, sodium carbonate 5%, lipoic acid 6%, n-acetyl-L-cysteine 3.2%, surplus are water, enhance embryo
Activity is become pregnant probability to enhance parent.
Further, protection liquid storehouse internal injection has protection liquid, the protection liquid by following weight percent at
It is grouped as: creatinine 0.84%, vernix caseosa linoleic acid 0.54%, beta carotene 0.5%, palmitinic acid 0.8%, L-Glutamine
0.45%, polylactic-co-glycolic acid 0.32%, beta -mercaptoethanol 0.16%, human serum albumin 2.3%, vitamin
B1.2%, epidermal growth factor 0.02% and insulin 0.12%, hydrocortisone 0.23,;Cortisol 0.04%, progesterone
0.94%, L-Glutamine 0.74%, HEPES0.84% stimulate parent by protection liquid, carry out pregnancy reaction.
Further, the pH of the described nutrient solution sum is 6.9-7.2, osmotic pressure 312-322KPa, it is ensured that embryo health hair
It educates.
Further, the pH of the protection liquid is 6.9-7.2, osmotic pressure 312-322KPa, it is ensured that embryo health development.
Working method of the invention:
S1: determining injection position by inspection equipment, embryo and its nutrient solution be injected into embryo storehouse by syringe, will
Protection liquid is injected into inside protection liquid storehouse, and embryo storehouse is discharged by pushing ram one and pushing ram two and protects the air in liquid storehouse,
Then fixed disk is adjacent at the skin of parent injection position.
S2: driving rack rails one to move upwards by rotate gear two, so that pushing ram two be driven to move upwards, protection liquid from
Pipeline two is introduced into pipeline one, then reaches hose front end, when liquid to be protected is overflowed from needle position, rotate gear one is by syringe needle
It is pierced into inside maternal uterine, when syringe needle is pierced into maternal uterine, rotating wheel disk makes inside the extended needle of hose head, pushes to promote and press
After embryo storehouse internal liquid is discharged in button, rotate gear two makes after protecting liquid storehouse remaining liq to be all discharged again, removes the present apparatus.
The beneficial effects of the present invention are:
The present invention pushes the nutrient solution comprising embryo to advance to maternal uterine by protection liquid, after syringe needle enters intrauterine,
Made inside the extended needle of hose head by rotating wheel disk, in this way when extracting syringe needle, syringe needle avoided to scratch embryonic cell,
And influence the health condition of embryo, fixed disk can stabilising arrangement, avoid syringe needle from generating in maternal and be displaced by a relatively large margin, from
And uterus inner wall is scratched, the present invention greatly enhances protection of the embryo transfer in the process to embryo, so as to avoid embryo's shifting
To the injury of embryo during plant.
Detailed description of the invention
Fig. 1 is the structure chart of invention;
Fig. 2 is the structure chart at invention wheel disc;
Fig. 3 is the left view of the fixed disk of invention;
Fig. 4 is the sheet metal of invention and the connection figure of pushing ram two.
Wherein, 1- fixed link, 2- hold in the palm handle, 3- hose, 4- hollow shaft, 5- pipeline one, 6- pipeline two, 11- fixed disk, 12-
Channel, 13- syringe needle, 14- rack rails one, 15- rotating bar, 16- gear one, 17- wheel disc, 21- embryo storehouse, 22- embryo storehouse promote dress
Set, 23- protection liquid storehouse, 24- protection liquid storehouse propulsion device, 25- gear two, 111- disk body, 112- centre bore, 113- sucker,
114- connecting column, 41- limited post, 221- gasket one, 222- pushing ram one, 223- promote button, 241- gasket two, 242-
Pushing ram two, 243- strip groove, 244- sheet metal, 245- rack rails two.
Specific embodiment
To be further explained explanation below with reference to Fig. 1-2, embodiment is simultaneously convenient for the understanding to technical solution of the present invention
Do not constitute limiting the scope of the present invention.
Embodiment 1:
As shown in Figure 1, a kind of embryo transplanter for test-tube baby, including fixed link 1, support are 2, hose 3, hollow shaft
4, pipeline 1, pipeline 26,1 front end of fixed link are connected with fixed disk 11 by card slot, as shown in figure 3, fixed disk 11 includes disk
Body 111, centre bore 112, sucker 113, connecting column 114, centre bore 112 are located at the center of disk body 111, and there are four connecting columns 114,
Four connecting columns 114 are uniformly distributed circumferentially in 111 front end of disk body, and there are four suckers 113, and four suckers 113 are separately fixed at
The front end of connecting column 114 reduces syringe needle in the intracorporal movement of parent by fixed disk, and the middle part of fixed link 1 is transversely provided with channel
12, it is equipped with syringe needle 13 inside channel 12, is equipped with rack rails 1 on the downside of 13 rear end of syringe needle, 1 middle part lower end of fixed link passes through rotating bar
15 are rotatably connected to gear 1, and one 14 engaged transmission of gear 1 and rack rails, 1 rear end of fixed link is connected by the rotation of hollow shaft 4
It is connected to wheel disc 17, as shown in Fig. 2, 17 center of wheel disc is fixedly connected with hollow shaft 4, the left end of hollow shaft 4 passes through card slot and pipeline
The right end of one 5 rotation connections, hollow shaft 4 is equipped with limited post 41, and the right end of limited post 41 is fixedly connected with the inner wall of fixed link 1,
The left end of limited post 41, by wheel disc by flexible pipe extending needle wall, avoids syringe needle to embryo for limiting to hollow shaft 4
It scratches, support is connected to below the rear end of fixed link 12, and 2 rear side upper end is set embryo storehouse 21 by support, is connected below embryo storehouse 21
There is embryo storehouse propulsion device 22, embryo storehouse propulsion device 22 includes gasket 1, pushing ram 1, promotes button 223, close
Packing 1 is located at the lower end inside embryo storehouse 21, and one 222 upper end of pushing ram is fixedly connected with gasket 1, pushing ram one
222 lower ends pass through support and 2 outer walls are fixedly connected with button 223 is promoted, by promoting button that embryo storehouse internal liquid is quickly discharged,
The lower section in embryo storehouse 21 is fixed with protection liquid storehouse 23, and embryo storehouse 21 is for nutrient solution needed for storing embryo and embryonic development, battalion
Nutrient solution enhances embryo viability, becomes pregnant probability to enhance parent, and protection 23 internal injection of liquid storehouse has protection liquid, and protection liquid stimulation is female
Body carries out pregnancy reaction, and protecting the pH of liquid is 6.9-7.2, and osmotic pressure 312-322KPa, the pH of nutrient solution sum are 6.9-7.2,
Osmotic pressure is 312-322KPa, it is ensured that embryo health development, it is ensured that embryo health development, protection 23 lower end of liquid storehouse are connected with protection
Liquid storehouse propulsion device 24, protection liquid storehouse propulsion device 24 include gasket 2 241, pushing ram 2 242, strip groove 243, sheet metal
244, rack rails 2 245, gasket 2 241 are located at the lower end inside protection liquid storehouse 23,2 242 upper end of pushing ram and gasket two
241 are fixedly connected, and strip groove 243 is located at the right side of gear 2 25, and rack rails 2 245 is located inside strip groove 243 vertically, sheet metal
244 are fixed on the right side inner wall of strip groove 243 vertically, as shown in figure 4, passing through sheet metal 244 on the left of the lower end of pushing ram 2 242
Lower end is fixedly connected with 2 245 lower end of rack rails, the discharge rate of protection liquid is accurately controlled by gear two, support is 2 front ends by turning
Lever 15 is connected with gear 2 25, and 24 engaged transmission of gear 2 25 and protection liquid storehouse propulsion device, 3 front end of hose is laterally set on
Inside syringe needle 13, be wrapped in the middle part of hose 3 on wheel disc 17,3 end of hose is connect with hollow shaft 4, embryo storehouse 21 and hollow shaft 4 it
Between communicated by pipeline 1, protect and communicated between liquid storehouse 23 and pipeline 1 by pipeline 26.
Embodiment 2:
As shown in Figure 1, a kind of embryo transplanter for test-tube baby, including fixed link 1, support are 2, hose 3, hollow shaft
4, pipeline 1, pipeline 26,1 front end of fixed link are connected with fixed disk 11 by card slot, as shown in figure 3, fixed disk 11 includes disk
Body 111, centre bore 112, sucker 113, connecting column 114, centre bore 112 are located at the center of disk body 111, and there are four connecting columns 114,
Four connecting columns 114 are uniformly distributed circumferentially in 111 front end of disk body, and there are four suckers 113, and four suckers 113 are separately fixed at
The front end of connecting column 114 reduces syringe needle in the intracorporal movement of parent by fixed disk, and the middle part of fixed link 1 is transversely provided with channel
12, it is equipped with syringe needle 13 inside channel 12, is equipped with rack rails 1 on the downside of 13 rear end of syringe needle, 1 middle part lower end of fixed link passes through rotating bar
15 are rotatably connected to gear 1, and one 14 engaged transmission of gear 1 and rack rails, 1 rear end of fixed link is connected by the rotation of hollow shaft 4
It is connected to wheel disc 17, as shown in Fig. 2, 17 center of wheel disc is fixedly connected with hollow shaft 4, the left end of hollow shaft 4 passes through card slot and pipeline
The right end of one 5 rotation connections, hollow shaft 4 is equipped with limited post 41, and the right end of limited post 41 is fixedly connected with the inner wall of fixed link 1,
The left end of limited post 41, by wheel disc by flexible pipe extending needle wall, avoids syringe needle to embryo for limiting to hollow shaft 4
It scratches, support is connected to below the rear end of fixed link 12, and 2 rear side upper end is set embryo storehouse 21 by support, is connected below embryo storehouse 21
There is embryo storehouse propulsion device 22, embryo storehouse propulsion device 22 includes gasket 1, pushing ram 1, promotes button 223, close
Packing 1 is located at the lower end inside embryo storehouse 21, and one 222 upper end of pushing ram is fixedly connected with gasket 1, pushing ram one
222 lower ends pass through support and 2 outer walls are fixedly connected with button 223 is promoted, by promoting button that embryo storehouse internal liquid is quickly discharged,
The lower section in embryo storehouse 21 is fixed with protection liquid storehouse 23, and embryo storehouse 21 is for nutrient solution needed for storing embryo and embryonic development, battalion
Nutrient solution is by following weight percent at being grouped as: 0.02% penicillin, compound amido acid injection 5%, human serum albumin
6.3%, potassium chloride 1.2%, magnesium sulfate 0.5%, glucose 6%, gentamicin 0.08%, ethylenediamine tetra-acetic acid 3.2%, acetone
Sour sodium 2.2%, alanyl glutamine 1.5%, taurine 0.85%, D-glucitol 1.2%, calcium chloride 0.9%, biphosphate
Sodium 0.5%, potassium dihydrogen phosphate 0.7%, sodium carbonate 5%, lipoic acid 6%, n-acetyl-L-cysteine 3.2%, surplus are
Water enhances embryo viability, becomes pregnant probability to enhance parent, and protection 23 internal injection of liquid storehouse has protection liquid, protects liquid by following
Weight percent at being grouped as: creatinine 0.84%, vernix caseosa linoleic acid 0.54%, beta carotene 0.5%, palmitinic acid 0.8%,
L-Glutamine 0.45%, polylactic-co-glycolic acid 0.32%, beta -mercaptoethanol 0.16%, human serum albumin 2.3%L,
Vitamin B1 .2%, epidermal growth factor 0.02% and insulin 0.12%, hydrocortisone 0.23%, cortisol 0.04%,
Progesterone 0.94%, L-Glutamine 0.74%, HEPES0.84% stimulate parent by protection liquid, carry out pregnancy reaction, protect
The pH for protecting liquid is 6.9-7.2, and osmotic pressure 312-322KPa, the pH of nutrient solution sum are 6.9-7.2, osmotic pressure 312-
322KPa, it is ensured that embryo health development, it is ensured that embryo health development, protection 23 lower end of liquid storehouse are connected with protection liquid storehouse propulsion device
24, protection liquid storehouse propulsion device 24 includes gasket 2 241, pushing ram 2 242, strip groove 243, sheet metal 244, rack rails two
245, gasket 2 241 is located at the lower end inside protection liquid storehouse 23, and 2 242 upper end of pushing ram is fixedly connected with gasket 2 241,
Strip groove 243 is located at the right side of gear 2 25, and rack rails 2 245 is located inside strip groove 243 vertically, and sheet metal 244 is fixed vertically
In the right side inner wall of strip groove 243, as shown in figure 4, passing through 244 lower end of sheet metal and rack rails on the left of the lower end of pushing ram 2 242
2 245 lower ends are fixedly connected, and the discharge rate of protection liquid is accurately controlled by gear two, and support is connected 2 front ends by rotating bar 15
There is gear 2 25,24 engaged transmission of gear 2 25 and protection liquid storehouse propulsion device, 3 front end of hose is laterally set in syringe needle 13
Portion is wrapped on wheel disc 17 in the middle part of hose 3, and 3 end of hose is connect with hollow shaft 4, passes through pipe between embryo storehouse 21 and hollow shaft 4
Road 1 communicates, and protects and is communicated between liquid storehouse 23 and pipeline 1 by pipeline 26.
The working method of the present embodiment:
S1: determining injection position by inspection equipment, embryo and its nutrient solution be injected into embryo storehouse by syringe, will
Protection liquid is injected into inside protection liquid storehouse, and is matched granary by pushing ram one and the discharge of pushing ram two and protected the air in liquid storehouse,
Then fixed disk is adjacent at the skin of parent injection position.
S2: driving rack rails one to move upwards by rotate gear two, so that pushing ram two be driven to move upwards, protection liquid from
Pipeline two is introduced into pipeline one, then reaches hose front end, when liquid to be protected is overflowed from needle position, rotate gear one is by syringe needle
It is pierced into inside maternal uterine, when syringe needle is pierced into maternal uterine, rotating wheel disk makes inside the extended needle of hose head, pushes to promote and press
After embryo storehouse internal liquid is discharged in button, rotate gear two makes after protecting liquid storehouse remaining liq to be all discharged again, removes the present apparatus.
The above described is only a preferred embodiment of the present invention, being not the limitation for making other forms to the present invention, appoint
What those skilled in the art changed or be modified as possibly also with the technology contents of the disclosure above equivalent variations etc.
Imitate embodiment.But without departing from the technical solutions of the present invention, according to the technical essence of the invention to above embodiments institute
Any simple modification, equivalent variations and the remodeling made, still fall within the protection scope of technical solution of the present invention.