CN109221146B - Use of triflumizole amine for reducing or preventing corn infection by helminthosporium macrostoma - Google Patents
Use of triflumizole amine for reducing or preventing corn infection by helminthosporium macrostoma Download PDFInfo
- Publication number
- CN109221146B CN109221146B CN201710557016.6A CN201710557016A CN109221146B CN 109221146 B CN109221146 B CN 109221146B CN 201710557016 A CN201710557016 A CN 201710557016A CN 109221146 B CN109221146 B CN 109221146B
- Authority
- CN
- China
- Prior art keywords
- amine
- helminthosporium
- plant
- corn
- seeds
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
Classifications
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N3/00—Preservation of plants or parts thereof, e.g. inhibiting evaporation, improvement of the appearance of leaves or protection against physical influences such as UV radiation using chemical compositions; Grafting wax
Abstract
The invention relates to application of thiabendazole in reducing or preventing corn from being infected by helminthosporium macrosporum. The invention also relates to a method for reducing or preventing the infestation of maize by toxins formed by Helminthosporium magnum by treating the pathogen and/or its environment, or the plant, plant propagation material and plant organs, soils, materials or spaces, stores which grow out later, with the fluindacamide or with the fluindacamide-containing fungicidal compositions.
Description
Technical Field
The invention relates to the use of triflumizole amine for reducing or preventing the infestation of maize by helminthosporium macrosporum.
Background
Northern leaf blight is an important disease in corn production in the world. The asexual pathogen of the northern leaf blight of corn is Helminthosporium magnum, belonging to the genus Helminthosporium of Deuteromycotina. The pathogenic bacteria of the northern leaf blight of corn overwinter in the disease residues by using mycelia, which become main primary infection sources of diseases in the next year, and manure with non-rotten disease residues and diseased seeds can also become primary infection sources. Northern leaf blight mainly damages leaves, leaf sheaths and bracts of corn.
In order to reduce or prevent the corn from being infected by the helminthosporium macrostoma fungus, the currently used measures are mainly as follows:
-cultivating a cultivar that is not susceptible to infection by helminthosporium macrosporum;
-suitable rotation; in particular, the corn is avoided being used as the previous crop; the crop rotation is carried out for more than 2 years in the seriously ill field,
after harvesting, timely removing the field disease residues and fallen leaves, carrying out centralized treatment, and carrying out deep ploughing and stubble cleaning.
-storage conditions that prevent the development of helminthosporium macrostoma;
-enhancing fertilizer and water management; promoting the growth of the corn and preventing the late premature senility of the corn;
-pharmacological control.
However, these purely preventive measures are not satisfactory and the efficacy is not reliable, especially when the prevailing climatic conditions favor fungal infestation. It is therefore an object of the present invention to provide a compound for reducing or preventing the infestation of maize by toxins formed by helminthosporium macrosporum.
Disclosure of Invention
The object of the present invention is to provide, in view of the above-mentioned disadvantages, a compound for reducing or preventing the infestation of maize by toxins formed by helminthosporium macrosporum.
The present inventors have surprisingly found that triflumizole amine performs well in reducing or preventing corn infestation by the toxin formed by helminthosporium macrosporum.
Fluindachazole, CAS: 1383809-87-7; the chemical name is 3-difluoromethyl-N- (7-fluoro-1, 1, 3-trimethyl-4-indanyl) -1-methyl-4-pyrazolecarboxamide; the molecular structural formula is as follows:
fluindacamide was developed by I-F, a compound which has been disclosed in CN 103502220.
The present fluoroandenazole amine can be the racemic mixture (I) -RS, or an enriched mixture of one of the two enantiomers, or the substantially pure particular enantiomer (I) -R or (I) -S.
(I)-R (I)-S
Of the two enantiomeric forms of fluoroandenazole amine, the substantially pure isomer R is preferred.
The invention provides application of thiabendazole in reducing or preventing corn from being infected by helminthosporium macrostoma.
The invention also provides a bactericidal composition containing the fluindacazole amine, which comprises the active component of the fluindacazole amine, a filler and/or a surfactant.
In the bactericidal composition containing the fluoroandenconazole, the fluoroandenconazole accounts for 1% to 90% of the total weight of the bactericidal composition, preferably 1% to 80%, more preferably 1% to 70%, more preferably 1% to 60%, more preferably 1% to 50%, and more preferably 5% to 50%.
The bactericidal composition containing the indoxacarb provided by the invention can be prepared into any agriculturally allowable dosage form. The dosage form of the bactericidal composition is suspending agent, seed coating agent, wettable powder, water dispersible granules, microcapsule suspending agent, coated granules, extruded granules, missible oil, microemulsion, emulsion in water, effervescent tablets, ultra-low volume liquid and electrostatic oil agent.
The bactericidal composition containing the indoxacarb can be applied without dilution or diluted by water.
The invention provides application of a bactericidal composition containing indoxacarb in reducing or preventing corn from being infected by helminthosporium macrosporum.
The use of the bactericidal composition containing indacazolium fluoride or containing indacazolium fluoride to reduce or prevent infestation of plants, plant propagation material and subsequently emerging plant organs by toxins formed by helminthosporium macrostoma.
The application of the thiabendazole-containing or thiabendazole-containing bactericidal composition to a place needing control reduces or prevents the infection of soil or culture medium by toxin formed by the helminthosporium macrostoma.
The use of the thiabendazole or the fluorochemical thiabendazole composition for treating seeds to reduce or prevent infection of the seeds by toxins formed by helminthosporium macrostoma.
The invention provides a method for reducing or preventing corn from being infected by toxins formed by Helminthosporium magnum, and the sterilization composition containing the flurindoxacarb or the flurindoxacarb is used for treating pathogenic bacteria and/or the environment thereof, or plants, plant propagation materials and plant organs, soil, materials or spaces and storage matters grown later.
A method for reducing or preventing corn infestation by the toxin formed by Helminthosporium magnum, the pathogenic bacteria and/or their environment, or plants, plant propagation material and subsequently plant organs, soils, materials or spaces, stores, are treated with fluroindolizidine or a fluroindolizidine-containing fungicidal composition in the form of seed treatment, foliar application, stem application, impregnation, drip, pour, spray, dusting, scattering or fuming.
A method for reducing or preventing corn infestation by the toxin formed by Helminthosporium magnum comprises applying to the plant or plant part a fungicidal composition comprising sulfenamide or sulfenamide.
A method for reducing or preventing corn infestation by toxins formed by Helminthosporium magnum comprises applying to the plant propagation material and the plant organs which grow out subsequently a fungicidal composition containing fluroindolizidine or fluroindolizidine.
A method for reducing or preventing corn infestation by the toxin formed by Helminthosporium magnum comprises applying to the soil or cultivation medium a fungicidal composition containing fluroinconazole or fluroinconazole.
The present invention provides a compound for reducing or preventing corn infestation by toxin formed by helminthosporium macrosporum.
The present inventors have surprisingly found that triflumizole amine performs well in reducing or preventing corn infestation by the toxin formed by helminthosporium macrosporum.
The invention also provides application of the bactericidal composition containing the indoxacarb in reducing or preventing the corn from being infected by the helminthosporium macrostoma.
Detailed Description
Corn can be infected with northern leaf blight throughout the entire growing period. Under natural conditions, the disease resistance exists in stages, the disease is rarely developed in the seedling stage, and the disease is gradually increased in the later growth stage of the corn, particularly after the male extraction. Germs mainly harm leaves, and in severe cases, can also harm leaf sheaths, bracts and seeds. The disease spots on the leaves can also be damaged, the disease spots spread along the veins, and the disease spots are yellow brown or grey brown, spindle-shaped large spots, the middle color of the disease spots is darker than the edge. The corn northern leaf blight pathogenic fungus is corn northern leaf blight helminthosporium, and belongs to Deuteromycotina Hippocastium fungus.
The pathogenic bacteria of the northern leaf blight of corn overwinter in the disease residues by using mycelia, which become main primary infection sources of diseases in the next year, and manure with non-rotten disease residues and diseased seeds can also become primary infection sources. Conidia generated after the bacteria live through the winter are mainly spread by wind, rain and air flow, the germ tube conditions are suitable for germination, most of the conidia grow from top cells of the spores, and basal cells and even intermediate cells of the spores can also grow out of the germ tube.
The present invention provides a compound for reducing or preventing corn infestation by toxin formed by helminthosporium macrosporum.
The present inventors have surprisingly found that triflumizole amine performs well in reducing or preventing corn infestation by the toxin formed by helminthosporium macrosporum.
The invention provides application of thiabendazole in reducing or preventing corn from being infected by helminthosporium macrostoma.
Fluindachazole, CAS: 1383809-87-7; the chemical name is 3-difluoromethyl-N- (7-fluoro-1, 1, 3-trimethyl-4-indanyl) -1-methyl-4-pyrazolecarboxamide; the molecular structural formula is as follows:
fluindacamide was developed by I-F, a compound which has been disclosed in CN 103502220.
The present fluoroandenazole amine can be the racemic mixture (I) -RS, or an enriched mixture of one of the two enantiomers, or the substantially pure particular enantiomer (I) -R or (I) -S.
(I)-R (I)-S
Of the two enantiomeric forms of fluoroandenazole amine, the substantially pure isomer R is preferred.
The invention also provides a bactericidal composition containing the fluindacazole amine, which comprises the active component of the fluindacazole amine, a filler and/or a surfactant.
In the bactericidal composition containing the fluoroandenconazole, the fluoroandenconazole accounts for 1% to 90% of the total weight of the bactericidal composition, preferably 1% to 80%, more preferably 1% to 70%, more preferably 1% to 60%, more preferably 1% to 50%, and more preferably 5% to 50%.
The thiabendazole can be administered directly, in the form of its formulation or in the use form prepared therefrom. Conventional formulations are, for example, suspensions, seed coatings, wettable powders, water dispersible granules, microcapsule suspensions, coated granules, extruded granules, emulsifiable concentrates, microemulsions, aqueous emulsions, effervescent tablets, ultra-low volume liquids, electrostatic oils. In each formulation form, the best possible distribution of the active compound fluoroandenazole amine used according to the invention and of the fillers and/or surfactants should be ensured.
The formulations of the invention can be prepared by mixing the active ingredient, aciflufen, with fillers and/or surfactants in a known manner, it being possible for further conventional additives, such as siccatives and colorants, stabilizers, pigments, defoamers, preservatives, thickeners, etc., to be added.
According to the present invention, the term "filler" refers to a natural or synthetic organic or inorganic compound that can be combined or associated with an active compound to make it easier to apply to a subject (e.g. plants, crops or grasses). Thus, the filler is preferably inert, at least should be agriculturally acceptable. The filler may be solid or liquid.
Liquid fillers are typically: water, alcohols (e.g., methanol, ethanol, isopropanol, butanol, ethylene glycol, etc.), ketones (e.g., acetone, methyl ethyl ketone, diisobutyl ketone, cyclohexanone, etc.), ethers (e.g., diethyl ether, dioxane, methyl cellulose, tetrahydrofuran, etc.), aliphatic hydrocarbons (e.g., kerosene, mineral oil, etc.), aromatic hydrocarbons (e.g., benzene, toluene, xylene, mineral spirits, alkylnaphthalenes, chlorinated aromatic hydrocarbons, chlorinated aliphatic hydrocarbons, chlorobenzene, etc.), halogenated hydrocarbons, amides, sulfones, dimethyl sulfoxide, mineral and vegetable oils, animal oils, etc.
Solid fillers are typically: examples of the inorganic filler include vegetable powders (for example, particles of soybean powder, starch, cereal powder, wood powder, bark powder, saw dust, walnut shell powder, bran, cellulose powder, coconut shell, corn cob, and tobacco stalk, and residues after extraction of plant essence), paper, saw dust, synthetic polymers such as ground synthetic resins, clays (for example, kaolin, bentonite, and acid china clay), and talc powders. Silica (for example, diatomaceous earth, silica sand, mica, hydrous silicic acid, calcium silicate), activated carbon, natural minerals (for example, pumice, attapulgite, zeolite, etc.), calcined diatomaceous earth, sand, plastic media (for example, polyethylene, polypropylene, polyvinylidene chloride, etc.), inorganic mineral powders such as potassium chloride, calcium carbonate, calcium phosphate, etc., chemical fertilizers such as ammonium sulfate, ammonium phosphate, urea, ammonium chloride, etc., and soil fertilizers, and these may be used alone or in combination of 2 or more.
Examples of the surfactant that can be used for emulsifying, dispersing, solubilizing, and/or wetting the active ingredient compound include polyacrylic acid salts such as fatty alcohol polyoxyethylene ether, polyoxyethylene alkylaryl ether, polyoxyethylene higher fatty acid ester, phosphoric acid ester of polyoxyethylene alcohol or phenol, fatty acid ester of polyhydric alcohol, alkylaryl sulfonic acid, naphthalenesulfonic acid polymer, lignosulfonate, branched polymer of high molecular comb, butylnaphthalenesulfonate, alkylaryl sulfonate, sodium alkylsulfosuccinate, fats and oils, condensates of fatty alcohol and ethylene oxide, and alkyltaurates, and protein hydrolysates. Suitable oligosaccharides or polymers are based, for example, on ethylene monomers, acrylic acid, polyoxyethylene and/or polyoxypropylene alone or in combination with, for example, (poly) alcohols or (poly) amines.
Tackifiers such as carboxymethylcellulose and natural and synthetic polymers in the form of powders, granules or latices, such as gum arabic, polyvinyl alcohol and polyvinyl acetate, or else natural phospholipids, such as cephalins and lecithins, and synthetic phospholipids, can also be used in the formulations. Other additives are mineral oils and vegetable oils.
It is possible to use colorants such as inorganic pigments, for example iron oxide, titanium oxide and Prussian blue, and organic dyes, such as alizarin dyes, azo dyes or metal phthalocyanine dyes, and trace nutrients, such as salts of iron, manganese, boron, ketones, cobalt, molybdenum and zinc.
Disintegrants which may be used are selected from: one or more of bentonite, urea, ammonium sulfate, aluminum chloride, citric acid, succinic acid and sodium bicarbonate.
Stabilizers which may be used are selected from: one of sodium citrate and resorcinol.
The antifreeze agents which may be used are selected from: one or more of ethylene glycol, propylene glycol, glycerol and urea.
The defoaming agent is selected from: silicone oil, Silicone Compound, C10-20 Saturated fatty acid compound, C8-10One or more of fatty alcohol compounds.
Optionally, further additional components, such as protective colloids, binders, thickeners, thixotropic agents, penetrating agents, stabilizers, masking agents, can also be included.
The bactericidal composition can also be mixed with other medicaments with weeding, insecticidal or bactericidal properties, particularly bactericides. If the thiabendazole amines are used in combination with other fungicides, they are preferably used in combination with one or two other fungicides.
The thiabendazole can also be applied in combination with the following fungicides:
acylalanines, such as benalaxyl (benalaxyl), metalaxyl (metalaxyl), methylfuroamide (ofarace), oxadixyl (oxadixyl);
amine derivatives, such as 4-dodecyl-2, 6-dimethylmorpholine (aldimorph), dodine (dodine), dodemorph (dodemorph), fenpropimorph (fenpropimorph), fenpropidin (fenpropidine), biguanide salts (guazatine), iminoctadine acetate (iminoctadine), spiroxamine (spiroxamine), tridemorph (tridemorph);
anilinopyrimidines, such as pyrimethanil, mepanipyrim or cyprodinil;
antibiotics, such as cycloheximide (cycloheximide), griseofulvin (griseofulvin), kasugamycin (kasugamycin), polymalemycin (natamycin), polyoxin (polyoxin) or streptomycin (streptomycin);
azoles, such as bitertanol (biterthanol), bromuconazole (bromoconazole), cyproconazole (cyproconazole), difenoconazole (difenoconazole), dinitonazole (dinitroconazol), fenbuconazole (fenbuconazole), fluquinconazole (fluquinconazole), flusilazole (flusilazole), hexaconazole (hexaconazole), imazalil (imazalil), myclobutanil (myclobutanil), penconazole (penconazole), propiconazole (propiconazole), prochloraz (prochloraz), prothioconazole (prothioconazole), tebuconazole (tebuconazole), triadimefon (triafol), triadimenol (triabendazole), triflumizole (triflumizole), triticonazole (triticonazole), 4- (4-methyl-5, 4-5-methyl-5-4-fluorophenyl) - [1, 6, 4, 6-methyl-triazole ] (1, 5, 4-5, 6-methyl-triazole [1, 6, 4, 5-methyl-triazole ];
dicarboximides, such as iprodione, myclozolin, procymidone, vinclozolin;
dithiocarbamates, such as ferbam, sodium (nabam), maneb, mancozeb, metam, metiram, propineb, polycarbamate, thiram, ziram, zineb;
-heterocyclic compounds such as dichlofluanid (anilazine), benomyl (benomyl), boscalid (boscalid), carbendazim (carbendazim), carboxin (carboxin), carboxin (oxacarbxin), cyazofamid (cyazofamid), dazomet (dazomet), dithianon (dithianon), famoxadone (famoxadone), fenamidone (fenamidone), isopimazalol (fenarimol), fuberidazole (fuberidazole), flutolanil (flutolanil), furamethozole (furametpyr), propiconazole (mepronil), pyrimethal (nuarimol), thiabendazole (benazol), proquinazid (proquinazid), praziquantel (pyrofenox), pyroquine (pyroquinon), quinazine (thioquinazine (thiflufen), thifluzamide (fenpyrazamide), thiflufenazamide (thifluzamide), thifluzamide (fenpyrazamide), thifluzamide (fenpyrane), thifluzamide (thiofenamide (thifluzamide), thifluzamide (fenpyrazamide (thifluzamide), thifluzamide (thiflu;
copper fungicides, such as bordeaux mixture, copper acetate, copper oxychloride (copperoxochloride), basic copper sulfate;
phenylpyrroles, such as fenpiclonil or fluoroxas (fluoroxonil);
sulfenic acid derivatives, such as captafol (captafol), captan (captan), dichlofluanid (dichlofluanid), folpet (folpet), tolylfluanid (tolyfluoride);
cinnamide and similar compounds, such as dimethomorph, flurbiprofen or flumorph.
Strobilurins (strobilurins), such as azoxystrobin (azoxystrobin), dimoxystrobin (dimoxystrobin), fluoxastrobin (fluoxastrobin), kresoxim-methyl (kresoxim-methyl), metominostrobin (metominobin), orysastrobin (orysastrobin), picoxystrobin (picoxystrobin), or trifloxystrobin (trifloxystrobin);
other fungicides, such as thiadiazoline (acibenzolar-S-methyl), benthiavalicarb (benthiavalicarb), chlorocyclopropanamide (carpropamid), chlorothalonil (chlorothalonil), cyflufenamid (cyflufenamid), cymoxanil (cymoxanil), diclomezine (diclomezine), diclocyanamide (diclocymet), diethofencarb (diethofencarb), edifenphos (edifenphos), ethaboxam (ethaboxam), fenhexamid (fenhexamid), fenhexamid (fenoxanil), pyrimethanzone (ferimzone), fluazinam (fluazinam), fosetyl-aluminium (foseyl-alum), iprovalicarb, hexachlorobenzene (hexazemazone), chlorothalonil (penfluniprol), penfluniumuron (penfluniprol), penfluniprol (penfluniprol), penoxsulam (penoxsulam), penoxsulam (thiophanate), penoxsulam), chlorothalonil (thiophanate), penoxsulide (thiophanate), penoxsulide.
The composition of the invention can be mainly prepared in the form of preparation, namely, the substances in the composition are mixed; the ingredients of the composition may also be provided in a single dose, mixed in a tub or tank prior to use, and then diluted to the desired concentration. Wherein the formulation provided by the invention is preferably used as the main ingredient.
The use of the bactericidal composition containing indacazolium fluoride or containing indacazolium fluoride to reduce or prevent infestation of plants, plant propagation material and subsequently emerging plant organs by toxins formed by helminthosporium macrostoma.
The application of the thiabendazole-containing or thiabendazole-containing bactericidal composition to a place needing control reduces or prevents the infection of soil or culture medium by toxin formed by the helminthosporium macrostoma.
The use of the thiabendazole or the fluorochemical thiabendazole composition for treating seeds to reduce or prevent infection of the seeds by toxins formed by helminthosporium macrostoma.
The invention provides a method for reducing or preventing corn from being infected by toxins formed by Helminthosporium magnum, and the sterilization composition containing the flurindoxacarb or the flurindoxacarb is used for treating pathogenic bacteria and/or the environment thereof, or plants, plant propagation materials and plant organs, soil, materials or spaces and storage matters grown later.
A method for reducing or preventing corn infestation by the toxin formed by Helminthosporium magnum, the pathogenic bacteria and/or their environment, or plants, plant propagation material and subsequently plant organs, soils, materials or spaces, stores, are treated with fluroindolizidine or a fluroindolizidine-containing fungicidal composition in the form of seed treatment, foliar application, stem application, impregnation, drip, pour, spray, dusting, scattering or fuming.
A method for reducing or preventing corn infestation by the toxin formed by Helminthosporium magnum comprises applying to the plant or plant part a fungicidal composition comprising sulfenamide or sulfenamide.
A method for reducing or preventing corn infestation by toxins formed by Helminthosporium magnum comprises applying to the plant propagation material and the plant organs which grow out subsequently a fungicidal composition containing fluroindolizidine or fluroindolizidine.
A method for reducing or preventing corn infestation by the toxin formed by Helminthosporium magnum comprises applying to the soil or cultivation medium a fungicidal composition containing fluroinconazole or fluroinconazole.
The application time, the number of applications and the application rate used in each case must be adapted to the prevailing conditions and must be determined by the person skilled in the art for each individual case.
Treatment with the present bactericidal composition with diflunisal or fluindacamide can be protective and therapeutic. Before or after infestation by harmful fungi. Preferably, it is carried out as close as possible to the time of infection, i.e.before or after infection as close as possible to the time point of infection.
The bactericidal composition containing the triflumizole amine or the fluorine-containing triflumizole amine can be used as a foliar fungicide in crop protection, can also be used as a fungicide for seed dressing and soil fungicide, and can also be used as a preservative for postharvest stored materials.
The bactericidal composition of the present invention can treat all plants. "plant" means all plants and plant populations such as desirable and undesirable wild plants, cultivars, and plant varieties (whether or not protected by a plant variety or plant cultivar rights-to-human). Cultivated plants and plant varieties may be plants obtained by conventional propagation and cultivation methods, which may be supplemented or supplemented by one or more biotechnological methods, for example using dihaploids, protoplast fusion, random and directed mutations, molecular or genetic markers, or using bioengineering and genetic engineering methods. Plant parts are understood to mean all parts and organs of plants above and below the ground, such as shoots, leaves, flowers and roots, such as leaves, needles, stems, branches, flowers, fruit bodies, fruits and seeds, and also roots, bulbs and rhizomes. Also plants and vegetative and generative propagation material, for example cuttings, bulbs, rhizomes, runners and seeds, belong to the plant part.
The term "plant propagation material" is understood to mean all reproductively competent plant parts, such as seeds, which can be used for the propagation of the latter, and also vegetative materials, such as cuttings or tubers. Thus, plant parts as used herein include plant propagation material. Mention may be made, for example, of seeds, roots, fruits, tubers, bulbs, rhizomes and plant parts. Germinated plants and useful plants to be inhibited after germination or after emergence from the soil. The young plants can be protected prior to transplantation by a total or partial treatment by dipping.
Preferred plant propagation material of the present invention is a seed. The fungicidal compositions of the present invention are also particularly suitable for the treatment of seeds. Most of the crop damage caused by harmful fungi is caused by the attack of the seeds during storage or after sowing and during or after germination of the plants. Plants are particularly sensitive to roots and shoots during the growing period and can cause death of the plant even if there is little damage. This stage is particularly critical, since it is very important to protect the seeds and the germinating plants by using suitable compositions.
The invention also relates in particular to the reduction or prevention of seed and germinating plants from infestation by the toxin formed by helminthosporium macrostoma by treating the seeds with the bactericidal compositions described herein or containing fluoroandenconazole. The method makes it unnecessary or at least significantly possible to additionally apply crop protection agents after sowing or after germination of the plants. On the other hand, the amount of active compound used is optimized with the fungicidal composition according to the invention in order to provide maximum protection of the seeds and the germinating plants from attack by phytopathogenic fungi, without the plants themselves being harmed by the active compound used.
The bactericidal composition containing the ninhydrin or the fluninconazole-containing bactericidal composition is suitable for being treated in a sufficiently stable state so that the treatment does not cause any damage to seeds. In general, the treatment of the seeds can be carried out at any point in time between picking and sowing. The seeds commonly used are isolated from the plant and from the cob, husk, stem, cuticle, hair or pulp. Thus, for example, seeds that have been picked, cleaned and dried to a moisture content of less than 15% may be used. Alternatively, seeds may be used which are dried, for example by treatment with water, and then dried again.
Examples of the method of seed treatment include a method of diluting a liquid or solid chemical, a method of directly immersing seeds in a liquid solution without dilution to allow the chemical to permeate the seeds, a method of mixing a solid chemical or liquid chemical with seeds to coat the seeds and thereby adhering the chemical to the surfaces of the seeds, and a method of spraying the chemical to the vicinity of the seeds while planting.
The control of phytopathogenic fungi which damage the post-emergent plants is effected primarily by treating the soil and the aerial parts of the plants with crop protection agents.
The bactericidal composition containing the ninhydrin or the fluindacamide can also be used for treating soil to reduce or prevent the corn from being infected by toxin formed by the helminthosporium grandiflorum. Examples of methods for applying a chemical to soil include a method in which a liquid chemical is diluted in water or applied without dilution directly to the roots of a plant or a seedling bed for raising seedlings, a method in which granules are sown to the roots of a plant or a seedling bed for raising seedlings by spraying a powder, a water dispersible granule or the like to soil and mixing with the whole soil before sowing, and a method in which a powder, a water dispersible granule or the like is diluted and sprayed to a planting hole or a planting furrow before sowing or planting a plant, and sowing is performed.
The bactericidal composition containing the ninhydrin or the fluindacamide can be used for treating plants or overground parts of the plants so as to reduce or prevent the corn from being infected by toxin formed by the helminthosporium macrostoma. When applied to plants or parts of plants above ground, it is used in the form of an aqueous spray. Application is preferably by spraying. The spray is sprayed over the entire above-ground portion of the plant or only over individual plant parts. The choice of the individual plant parts to which the spray liquid is to be applied depends on the plant species and its stage of development.
The present invention provides a fungicidal composition containing indacamprosate or fluroinacamide, which can be used for treating stored articles to reduce or prevent the infection of corn by toxin formed by helminthosporium macrostoma.
According to the invention, the term "stock" is understood to mean natural substances and processed forms thereof of plant or animal origin which have been derived from the natural life cycle and are intended to be preserved for a long period of time. Storage products of plant origin, for example plants or parts thereof, such as stems, leaves, tubers, seeds, fruits or grains, can be protected in the freshly harvested state or in processed form, such as (pre) drying, wetting, comminuting, grinding, pressing or baking. Or wood, in the form of coarse wood such as construction timber, utility poles and fences; or in finished form, such as furniture or articles made of wood. The animal-derived stock is hide, leather, hair, etc. The compositions according to the invention can prevent fungal or bacterial attack such as corrosion, discoloration or mildew on storage. "stock" is preferably understood to mean natural substances of plant origin and processed forms thereof.
The bactericidal composition containing the ninhydrin or the fluninazole-containing bactericidal composition can be processed by different processing methods:
-spraying a liquid comprising the fungicidal composition onto the above-ground parts of the plant;
-dusting, incorporating granules or powders in the soil, spraying around said plants and, in the case of tree injection or painting;
-coating or film coating the seeds of the plants.
The present invention provides a method of reducing or preventing infestation of corn by toxins formed by helminthosporium macrosporum, which may be a therapeutic, prophylactic or eradication method.
Typically for leaf treatment: 0.1 to 10000g/ha, preferably 10 to 1000g/ha, more preferably 50 to 500 g/ha; for dipping or instillation administration, the dosage may even be reduced, particularly when an inert substrate such as asbestos or perlite is applied;
-for seed treatment: 2-5000g/100kg of seeds, preferably 3-1000g/100kg of seeds;
-applying a treatment to the soil or water surface: 0.1 to 10000g/ha, preferably 1 to 1000 g/ha.
The above-mentioned dosages are only typical exemplary dosages, and the person skilled in the art will adjust the application rate in the actual application according to the actual circumstances and needs, in particular according to the nature of the plants or crops to be treated and the severity of the germs.
Indoor toxicity determination of pesticide
Virulence determination of Helminthosporium magnum
The inhibition effect of the medicament on the Helminthosporium magnum is measured by adopting a hypha growth rate inhibition method.
Dissolving the medicinal preparation with sterile water, preparing into mother liquor with suitable mass concentration effective for different bacteria, diluting into liquid medicine with equal-fold or equal-difference concentration, mixing with culture medium at a volume ratio of 1: 9 to obtain final medicine-holding plate, and comparing with the plate containing sterile water. The bacterial cake was punched out by a punch with a diameter of 6mm from the edge of the colony of 5d of the preculture, and inoculated face down onto a drug-containing plate (PDA medium) 4 times per treatment, and after culturing for 6d in an incubator at 26 ℃, the colony diameter of each treatment was investigated by the cross method. The inhibition ratio of each treatment was calculated according to the formula (1), and the data statistical analysis was performed using the DPS software, and the test was repeated 2 times.
Inhibition% = [ (control colony growth diameter-treated colony growth diameter)/control colony growth diameter ] × 100 (1)
Linear regression analysis is performed between the logarithm of the concentration (x) of the drug and the value of the inhibition rate (Y) to find the virulence regression equation (Y = a + bx) and the correlation coefficient (r), and then the effective inhibitory concentration (EC) is found50Value).
Table 1: toxicity test result for Helminthosporium magnum
The measurement result of a hypha growth rate method shows that the thiabendazole amine has higher toxicity on the growth of the hypha of the Helminthosporium macrostomum.
Determination of fungicidal Activity in corn-Verticillium maculosum resistance
In the 7-9 leaf stage of corn, spraying manually, applying the pesticide for 1 time when no disease occurs, firstly inoculating the corn northern leaf blight in the whole area, and applying the pesticide according to a scheme, wherein each plant contains 2-3g of corn northern leaf blight leaves crushed by a high-speed crusher.
The post-dose investigation was carried out. And randomly selecting three points for investigation in each cell, continuously taking 5 plants in each point, taking the three leaves of the stick as a whole, evaluating, counting 15 plants, grading according to comparison and local occurrence conditions by combining national standards, and evaluating the safety.
The corn northern leaf blight grading method comprises the following steps:
level 0: no disease.
Level 1: the area of the lesion spots accounts for less than 5% of the area of the whole leaf;
and 3, level: the area of the lesion spots accounts for 6-10% of the area of the whole leaf.
And 5, stage: the area of the lesion spots accounts for 11-25% of the area of the whole leaf.
And 7, stage: the area of the lesion spots accounts for 26-50% of the area of the whole leaf.
And 9, stage: the area of the lesion spots accounts for more than 51 percent of the area of the whole leaf.
Recording the investigation quantity and the leaf number of each level of disease, and calculating the disease incidence, the disease severity and the prevention and treatment effect.
The disease base before no medicine is calculated according to the following formula:
control effect (%) = [ (CK 1-PT 1)/CK 1 ]. times.100
CK1 is the control zone and PT1 is the treatment zone.
And observing the phytotoxicity condition 3d and 7d after the pesticide application, and evaluating the safety of the corn.
TABLE 2 Effect investigation of Fluindachlor-containing for controlling northern leaf blight
The test result shows that the penflufen shows excellent control effect on the northern leaf blight. The safety evaluation results of 3d and 7d after the application on the corn show that the penflufen is safe to the corn and has no phytotoxicity.
Claims (6)
1. A method for reducing or preventing corn infestation by the toxin formed by helminthosporium macrostoma, characterized in that plants or plant parts are acted on with fluoroandenazole amine or with a fungicidal composition containing fluoroandenazole amine, the application rate of the fluoroandenazole amine being from 10 to 1000 g/ha; treating seeds with the triflumizole amine or the bactericidal composition containing the triflumizole amine, wherein the application rate of the triflumizole amine is 2-5000g/100kg of seeds; the application rate of the triflumizole amine is 0.1-10000 g/ha.
2. The method according to claim 1, wherein the plant or plant part is treated with the fluoroandenconazole amine or the fluoroandenconazole-containing fungicidal composition at a rate of application of the fluoroandenconazole amine of from 50 to 500 g/ha.
3. The method according to claim 1, wherein the plant or plant part is treated with the fluoroandenconazole amine or the fluoroandenconazole-containing fungicidal composition at an application rate of 100 g/ha.
4. The method according to claim 1, wherein the bactericidal composition containing indacamide or fluroinacamide is applied to the plant or plant parts, seeds, soil or cultivation media before or after the corn is infected with Helminthosporium macrostoma.
5. The method according to claim 1, characterized in that the seeds are treated with triflumizole amine or a triflumizole-containing fungicidal composition at an application rate of 3 to 1000g per 100kg of seeds.
6. The method according to claim 1, characterized in that the soil or the cultivation medium is acted on with the fluoroandenconazole amine or the fluoroandenconazole-containing fungicidal composition, the application rate of the fluoroandenconazole amine being 1 to 1000 g/ha.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710557016.6A CN109221146B (en) | 2017-07-10 | 2017-07-10 | Use of triflumizole amine for reducing or preventing corn infection by helminthosporium macrostoma |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710557016.6A CN109221146B (en) | 2017-07-10 | 2017-07-10 | Use of triflumizole amine for reducing or preventing corn infection by helminthosporium macrostoma |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN109221146A CN109221146A (en) | 2019-01-18 |
| CN109221146B true CN109221146B (en) | 2021-04-06 |
Family
ID=65083497
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710557016.6A Active CN109221146B (en) | 2017-07-10 | 2017-07-10 | Use of triflumizole amine for reducing or preventing corn infection by helminthosporium macrostoma |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN109221146B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114766493A (en) * | 2022-04-29 | 2022-07-22 | 青岛恒宁生物科技有限公司 | Bactericidal composition containing agricultural antibiotic and application thereof |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103518725A (en) * | 2013-10-14 | 2014-01-22 | 安徽丰乐农化有限责任公司 | Bactericide taking boscalid as effective component and for rice field, wheat field and corn field |
| CN108719300A (en) * | 2017-04-20 | 2018-11-02 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT1403275B1 (en) * | 2010-12-20 | 2013-10-17 | Isagro Ricerca Srl | HIGH-ACTIVITY INDANYLANILIDES FUNGICIDE AND THEIR PHYTOSANITARY COMPOSITIONS |
-
2017
- 2017-07-10 CN CN201710557016.6A patent/CN109221146B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103518725A (en) * | 2013-10-14 | 2014-01-22 | 安徽丰乐农化有限责任公司 | Bactericide taking boscalid as effective component and for rice field, wheat field and corn field |
| CN108719300A (en) * | 2017-04-20 | 2018-11-02 | 江苏龙灯化学有限公司 | A kind of bactericidal composition |
Non-Patent Citations (1)
| Title |
|---|
| 甲氧基丙烯酸酯类等四大类杀菌剂市场概况及前景展望;严明等;《现代农药》;20161210(第6期);第1-11页 * |
Also Published As
| Publication number | Publication date |
|---|---|
| CN109221146A (en) | 2019-01-18 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| TWI617244B (en) | Fungicidal composition and the use thereof | |
| CN101690490B (en) | Bactericidal composition compounded by bromothalonil and methoxy acrylic acid esters | |
| CN105409961B (en) | A kind of bactericidal composition of containing fluazinam and its application | |
| Augusto et al. | Assessing systemicity of peanut fungicides through bioassay of plant tissues with Sclerotium rolfsii | |
| CN104322558A (en) | Sterilization composition and applications thereof | |
| CN104604939A (en) | Pesticide composite containing sophocarpidine | |
| UA77981C2 (en) | Fungicidal compositions based on pyridylmethylbenzamide derivative and valinamide derivative, method for curative or preventive control of phytopathogenic fungi of crops | |
| CN109221146B (en) | Use of triflumizole amine for reducing or preventing corn infection by helminthosporium macrostoma | |
| CN107372556A (en) | A kind of suspension seed-coating agent containing pyraclostrobin, amino-oligosaccharide and Diacloden | |
| CN114617127B (en) | Pesticide sterilization composition and application thereof | |
| CN111109268A (en) | Bactericidal composition containing kresoxim-methyl and tetraconazole | |
| CN110301445B (en) | Application of sterilization composition containing fentrazazole-ethyl and hymexazol in reducing or preventing crop diseases | |
| CN110710534B (en) | Application of sterilization composition containing fluopyram and mancozeb | |
| CN110710532B (en) | Application of bactericidal composition containing trifloxystrobin and difenoconazole | |
| CN108522515A (en) | A kind of application of the bactericidal composition containing kresoxim-methyl and tetraconazole | |
| CN107372548A (en) | Composition pesticide containing captan and fluorine azoles ring bacterium amine and application thereof | |
| CN103988843B (en) | A kind of bactericidal composition | |
| CN110810437B (en) | Application of bactericidal composition containing zinc thiazole and thiediazole copper | |
| CN108184861A (en) | A kind of bactericidal composition and its application containing pyraziflumid | |
| CN110710536B (en) | Application of bactericidal composition containing trifloxystrobin and mancozeb | |
| CN106172453B (en) | A kind of bactericidal composition and its application | |
| CN110301450A (en) | Tetrazolium pyrrole urethane is reducing or preventing the purposes in crop disease | |
| CN107439583A (en) | Contain imidacloprid, Difenoconazole, the seed treatment suspending agent of fludioxonil and its application method and application | |
| CN112998017B (en) | Application of composition containing kasugamycin and zinc thiazole in preventing and treating soft rot of dendrobium officinale | |
| CN110810427A (en) | Application of bactericidal composition containing zinc thiazole and benziothiazolinone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |