CN109200343A - A kind of sterilization spermicidal lubricant suitable for vagina - Google Patents
A kind of sterilization spermicidal lubricant suitable for vagina Download PDFInfo
- Publication number
- CN109200343A CN109200343A CN201810997860.5A CN201810997860A CN109200343A CN 109200343 A CN109200343 A CN 109200343A CN 201810997860 A CN201810997860 A CN 201810997860A CN 109200343 A CN109200343 A CN 109200343A
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- CN
- China
- Prior art keywords
- vagina
- sterilization
- lubricant
- double
- ammonium chloride
- Prior art date
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/043—Proteins; Polypeptides; Degradation products thereof
- A61L31/044—Collagen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/04—Macromolecular materials
- A61L31/042—Polysaccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/20—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials
- A61L2300/204—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing organic materials with nitrogen-containing functional groups, e.g. aminoxides, nitriles, guanidines
- A61L2300/208—Quaternary ammonium compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/412—Tissue-regenerating or healing or proliferative agents
Abstract
The present invention discloses a kind of sterilization spermicidal lubricant suitable for vagina, is made of the raw material of following weight percent: double-chain quaternary ammonium salt 0.5-2.0%, glycerol 1.5-2.5%, collagen peptide 2.0-10%, methylcellulose 1.5-2.5%, surplus are purified water.The present invention takes double-chain quaternary ammonium salt, glycerol, collagen peptide, methylcellulose to be used to prepare lubricant, double-chain quaternary ammonium salt has the benefits of spermicidal sterilization, glycerol has the benefits of lubrication, collagen peptide has the benefits of repairing wound mucous membrane, Methyl cellulose is known as the effect of thickening, and lubricant is made in above-mentioned raw materials, solve vagina cross-infection caused by sexual life, transmission, it is dry and astringent the problems such as, mucous membrane can be nourished simultaneously, improve vaginal environment.
Description
Technical field
The present invention relates to a kind of lubricants, and in particular to a kind of sterilization spermicidal lubricant suitable for vagina.
Background technique
Women is from the childbearing age excessively to old stage, since hypo-ovaria causes vaginal secretion ability to decline, yin
Road is gradually dry and astringent, and secretion is reduced, and keeps the insertion of sexual's penis difficult, seriously affects sexual life.Therefore it is needed in sexual life
Using lubricant, alleviate and improve vaginal dryness symptom.
In two sexual lifves, rubber condoms are typically used for, lubricant is applied to the outer surface of sheath, usual lubricant
The principle used is that should not have adverse reaction to human body, should not change the property and performance of sheath.But the non-sterile device of sheath
Tool, it is possible to cause female reproductive system to infect, there is the sheath of addition antibiotic and sulfa drugs on the market, but it is long-term
It will lead to female reproductive system flora imbalance using antibiotic, pathogenic bacteria are insensitive to antibiotic.
Summary of the invention
It is an object of that present invention to provide a kind of sterilization spermicidal lubricants suitable for vagina.
Based on above-mentioned purpose, the present invention takes following technical scheme:
A kind of sterilization spermicidal lubricant suitable for vagina, is made: double-chain quaternary ammonium salt 0.5- of the raw material of following weight percent
2.0%, glycerol 1.5-2.5%, collagen peptide 2.0-10%, methylcellulose 1.5-2.5%, surplus are purified water.
A kind of sterilization spermicidal lubricant suitable for vagina, is made: double-chain quaternary ammonium salt of the raw material of following weight percent
1.5%, glycerol 2.0%, collagen peptide 5.0%, methylcellulose 2.0%, surplus are purified water.
The double-chain quaternary ammonium salt is the mixture of dimercaptodimethyl ammonium chloride and myristyl benzyl dimethyl ammonium chloride.
The mass ratio of the dimercaptodimethyl ammonium chloride and myristyl benzyl dimethyl ammonium chloride is (30-40) ︰
(60-70).
The mass ratio of the dimercaptodimethyl ammonium chloride and myristyl benzyl dimethyl ammonium chloride is 35 ︰ 65.
A kind of preparation method of the sterilization spermicidal lubricant suitable for vagina, by double-chain quaternary ammonium salt, glycerol, collagen
Peptide, methylcellulose are made an addition in purified water by corresponding proportion, be stirred to get.
Application method: it is applied to the outer surface of sheath.
Compared with prior art, the invention has the following advantages:
The present invention takes double-chain quaternary ammonium salt, glycerol, collagen peptide, methylcellulose to be used to prepare lubricant, double-chain quaternary ammonium salt
There is the benefits of spermicidal sterilization, glycerol has the benefits of lubrication, and collagen peptide has the benefits of repairing wound mucous membrane, and Methyl cellulose is known as thickening
Effect, lubricant is made in above-mentioned raw materials, vagina cross-infection, transmission, dry and astringent etc. caused by sexual life is solved and asks
Topic, while mucous membrane can be nourished, improve vaginal environment.
Specific embodiment
When preparing in embodiment 1-4, dimercaptodimethyl ammonium chloride is commercially available with myristyl benzyl dimethyl ammonium chloride
Product, the purity of dimercaptodimethyl ammonium chloride are 90%, and the purity of myristyl benzyl dimethyl ammonium chloride is 85%.But it is following
It is the pure dimercaptodimethyl ammonium chloride and myristyl benzyl dimethyl ammonium chloride after converting when being calculated in embodiment.
Embodiment 1
A kind of sterilization spermicidal lubricant suitable for vagina, is made: double-chain quaternary ammonium salt 1.5% of the raw material of following weight percent
(mass ratio of dimercaptodimethyl ammonium chloride and myristyl benzyl dimethyl ammonium chloride is 35 ︰ 65), glycerol 2.0%, collagen
Protein peptides 5.0%, methylcellulose 2.0%, surplus are purified water.
A kind of preparation method of the sterilization spermicidal lubricant suitable for vagina, by double-chain quaternary ammonium salt, glycerol, collagen
Peptide, methylcellulose are made an addition in purified water by corresponding proportion, be stirred (revolving speed can be set as 30 revs/min) to get.
Embodiment 2
A kind of sterilization spermicidal lubricant suitable for vagina, is made: double-chain quaternary ammonium salt 0.5% of the raw material of following weight percent
(mass ratio of dimercaptodimethyl ammonium chloride and myristyl benzyl dimethyl ammonium chloride is 35 ︰ 65), glycerol 1.5%, collagen
Protein peptides 10%, methylcellulose 2.5%, surplus are purified water.
Preparation method is referring to embodiment 1.
Embodiment 3
A kind of sterilization spermicidal lubricant suitable for vagina, is made: double-chain quaternary ammonium salt 2.0% of the raw material of following weight percent
(mass ratio of dimercaptodimethyl ammonium chloride and myristyl benzyl dimethyl ammonium chloride is 30 ︰ 70), glycerol 2.5%, collagen
Protein peptides 8.0%, methylcellulose 2.2%, surplus are purified water.
Preparation method is referring to embodiment 1.
Embodiment 4
A kind of sterilization spermicidal lubricant suitable for vagina, is made: double-chain quaternary ammonium salt 1.0% of the raw material of following weight percent
(mass ratio of dimercaptodimethyl ammonium chloride and myristyl benzyl dimethyl ammonium chloride is 40 ︰ 60), glycerol 1.8%, collagen
Protein peptides 2.0%, methylcellulose 1.5%, surplus are purified water.
Preparation method is referring to embodiment 1.
5 assessment of performance of embodiment
According to Ministry of Public Health's disinfection technology standard (version in 2002), the method for 16.9.1.4 " measurement of pH value " measures embodiment
The pH value of lubricant made from 1-4；The method of 2.1.8.2 " antibacterial ring test ", the suppression to lubricant made from embodiment 1-4
Bacterium performance is tested；The method of the 2.3.5 articles " vaginal mucomembranous irritant test " tests the irritation of lubricant of the invention.
After measured, the pH value of the lubricant of embodiment 1-4 is average in 6.3-6.5.
Lubricant made from embodiment 1-4 is subjected to parallel test three times to Candida albicans respectively, it is straight to measure antibacterial ring size
Thus diameter average value proves that lubricant of the present invention has bacteriostasis in 10.40-10.50mm.
Through testing, lubricant of the invention belongs to nonirritant to large ear rabbit vaginal mucomembranous irritant test.
Claims (5)
1. a kind of sterilization spermicidal lubricant suitable for vagina, which is characterized in that be made of the raw material of following weight percent: double
Chain quaternary ammonium salt 0.5-2.0%, glycerol 1.5-2.5%, collagen peptide 2.0-10%, methylcellulose 1.5-2.5%, surplus are purifying
Water.
2. being suitable for the sterilization spermicidal lubricant of vagina as described in claim 1, which is characterized in that by following weight percent
Raw material be made: double-chain quaternary ammonium salt 1.5%, glycerol 2.0%, collagen peptide 5.0%, methylcellulose 2.0%, surplus be purifying
Water.
3. being suitable for the sterilization spermicidal lubricant of vagina as claimed in claim 1 or 2, which is characterized in that the double-strand quaternary ammonium
Salt is the mixture of dimercaptodimethyl ammonium chloride and myristyl benzyl dimethyl ammonium chloride.
4. being suitable for the sterilization spermicidal lubricant of vagina as claimed in claim 3, which is characterized in that the didecyldimethylammonium
The mass ratio of ammonium chloride and myristyl benzyl dimethyl ammonium chloride is (30-40) ︰ (60-70).
5. being suitable for the sterilization spermicidal lubricant of vagina as claimed in claim 4, which is characterized in that the didecyldimethylammonium
The mass ratio of ammonium chloride and myristyl benzyl dimethyl ammonium chloride is 35 ︰ 65.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810997860.5A CN109200343A (en) | 2018-08-29 | 2018-08-29 | A kind of sterilization spermicidal lubricant suitable for vagina |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810997860.5A CN109200343A (en) | 2018-08-29 | 2018-08-29 | A kind of sterilization spermicidal lubricant suitable for vagina |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109200343A true CN109200343A (en) | 2019-01-15 |
Family
ID=64985301
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810997860.5A Pending CN109200343A (en) | 2018-08-29 | 2018-08-29 | A kind of sterilization spermicidal lubricant suitable for vagina |
Country Status (1)
| Country | Link |
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| CN (1) | CN109200343A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114099792A (en) * | 2020-08-30 | 2022-03-01 | 上海名邦橡胶制品有限公司 | Human body lubricating liquid and preparation method thereof |
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| CN101347449A (en) * | 2007-07-16 | 2009-01-21 | 马得伦 | Constituent of sperm-blocking agent with contraceptive effect |
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| CN104306324A (en) * | 2014-10-10 | 2015-01-28 | 无锡贝迪生物工程有限公司 | Medical collagen gel and preparation method thereof |
| CN104958283A (en) * | 2015-06-02 | 2015-10-07 | 北京盛大康成医疗技术有限公司 | Alkalescence skin mucosa cleaning and disinfecting composition and preparing method and application thereof |
| CN105169374A (en) * | 2015-10-23 | 2015-12-23 | 东莞市达庆医疗器械有限公司 | Recombinant human collagen gel and preparation method thereof |
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| CN107789611A (en) * | 2017-10-31 | 2018-03-13 | 福建师范大学 | A kind of collagen peptide lubricating fluid and preparation method thereof |
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-
2018
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114099792A (en) * | 2020-08-30 | 2022-03-01 | 上海名邦橡胶制品有限公司 | Human body lubricating liquid and preparation method thereof |
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Application publication date: 20190115 |
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