CN109199470A - A kind of atrium shunting instrument - Google Patents
A kind of atrium shunting instrument Download PDFInfo
- Publication number
- CN109199470A CN109199470A CN201811273350.XA CN201811273350A CN109199470A CN 109199470 A CN109199470 A CN 109199470A CN 201811273350 A CN201811273350 A CN 201811273350A CN 109199470 A CN109199470 A CN 109199470A
- Authority
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- China
- Prior art keywords
- room disk
- atrium
- shunts
- instrument
- tap hole
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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- 210000002837 heart atrium Anatomy 0.000 title claims abstract description 68
- 239000003814 drug Substances 0.000 claims abstract description 10
- 229940079593 drug Drugs 0.000 claims abstract description 9
- 230000005764 inhibitory process Effects 0.000 claims abstract description 6
- 239000000956 alloy Substances 0.000 claims description 7
- KDLHZDBZIXYQEI-UHFFFAOYSA-N Palladium Chemical compound [Pd] KDLHZDBZIXYQEI-UHFFFAOYSA-N 0.000 claims description 6
- 229910045601 alloy Inorganic materials 0.000 claims description 6
- BASFCYQUMIYNBI-UHFFFAOYSA-N platinum Chemical group [Pt] BASFCYQUMIYNBI-UHFFFAOYSA-N 0.000 claims description 6
- 229910003460 diamond Inorganic materials 0.000 claims description 5
- 239000010432 diamond Substances 0.000 claims description 5
- 238000000034 method Methods 0.000 claims description 5
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- 239000000203 mixture Substances 0.000 claims description 3
- 229960001592 paclitaxel Drugs 0.000 claims description 3
- 229910052763 palladium Inorganic materials 0.000 claims description 3
- 229910052697 platinum Inorganic materials 0.000 claims description 3
- ZAHRKKWIAAJSAO-UHFFFAOYSA-N rapamycin Natural products COCC(O)C(=C/C(C)C(=O)CC(OC(=O)C1CCCCN1C(=O)C(=O)C2(O)OC(CC(OC)C(=CC=CC=CC(C)CC(C)C(=O)C)C)CCC2C)C(C)CC3CCC(O)C(C3)OC)C ZAHRKKWIAAJSAO-UHFFFAOYSA-N 0.000 claims description 3
- QFJCIRLUMZQUOT-HPLJOQBZSA-N sirolimus Chemical compound C1C[C@@H](O)[C@H](OC)C[C@@H]1C[C@@H](C)[C@H]1OC(=O)[C@@H]2CCCCN2C(=O)C(=O)[C@](O)(O2)[C@H](C)CC[C@H]2C[C@H](OC)/C(C)=C/C=C/C=C/[C@@H](C)C[C@@H](C)C(=O)[C@H](OC)[C@H](O)/C(C)=C/[C@@H](C)C(=O)C1 QFJCIRLUMZQUOT-HPLJOQBZSA-N 0.000 claims description 3
- 229960002930 sirolimus Drugs 0.000 claims description 3
- RCINICONZNJXQF-MZXODVADSA-N taxol Chemical compound O([C@@H]1[C@@]2(C[C@@H](C(C)=C(C2(C)C)[C@H](C([C@]2(C)[C@@H](O)C[C@H]3OC[C@]3([C@H]21)OC(C)=O)=O)OC(=O)C)OC(=O)[C@H](O)[C@@H](NC(=O)C=1C=CC=CC=1)C=1C=CC=CC=1)O)C(=O)C1=CC=CC=C1 RCINICONZNJXQF-MZXODVADSA-N 0.000 claims description 3
- 238000009434 installation Methods 0.000 claims description 2
- 229910001285 shape-memory alloy Inorganic materials 0.000 claims description 2
- 230000015572 biosynthetic process Effects 0.000 claims 1
- 206010019280 Heart failures Diseases 0.000 description 17
- 238000010586 diagram Methods 0.000 description 16
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- 208000038003 heart failure with preserved ejection fraction Diseases 0.000 description 11
- 230000001746 atrial effect Effects 0.000 description 6
- 230000004217 heart function Effects 0.000 description 5
- 238000002513 implantation Methods 0.000 description 5
- 230000002685 pulmonary effect Effects 0.000 description 5
- 206010007558 Cardiac failure chronic Diseases 0.000 description 4
- 230000036772 blood pressure Effects 0.000 description 4
- 208000024891 symptom Diseases 0.000 description 4
- 208000000059 Dyspnea Diseases 0.000 description 3
- 206010013975 Dyspnoeas Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000007774 longterm Effects 0.000 description 3
- 230000009467 reduction Effects 0.000 description 3
- 230000000694 effects Effects 0.000 description 2
- 230000006870 function Effects 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 238000010438 heat treatment Methods 0.000 description 2
- 230000002265 prevention Effects 0.000 description 2
- 208000002330 Congenital Heart Defects Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 235000003283 Pachira macrocarpa Nutrition 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 241001083492 Trapa Species 0.000 description 1
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- 230000002526 effect on cardiovascular system Effects 0.000 description 1
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- 230000008717 functional decline Effects 0.000 description 1
- 230000005831 heart abnormality Effects 0.000 description 1
- 208000038002 heart failure with reduced ejection fraction Diseases 0.000 description 1
- 210000005246 left atrium Anatomy 0.000 description 1
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- 230000004048 modification Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000001575 pathological effect Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 239000011148 porous material Substances 0.000 description 1
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- 238000005086 pumping Methods 0.000 description 1
- 230000029058 respiratory gaseous exchange Effects 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00743—Type of operation; Specification of treatment sites
- A61B2017/00796—Breast surgery
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00862—Material properties elastic or resilient
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00867—Material properties shape memory effect
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B17/00—Surgical instruments, devices or methods, e.g. tourniquets
- A61B2017/00831—Material properties
- A61B2017/00902—Material properties transparent or translucent
- A61B2017/00915—Material properties transparent or translucent for radioactive radiation
- A61B2017/0092—Material properties transparent or translucent for radioactive radiation for X-rays
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0014—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof using shape memory or superelastic materials, e.g. nitinol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0067—Means for introducing or releasing pharmaceutical products into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2250/00—Special features of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2250/0058—Additional features; Implant or prostheses properties not otherwise provided for
- A61F2250/0096—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers
- A61F2250/0098—Markers and sensors for detecting a position or changes of a position of an implant, e.g. RF sensors, ultrasound markers radio-opaque, e.g. radio-opaque markers
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Surgery (AREA)
- Heart & Thoracic Surgery (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Transplantation (AREA)
- Medical Informatics (AREA)
- Molecular Biology (AREA)
- Prostheses (AREA)
Abstract
A kind of atrium shunting instrument to develop, comprising: current divider bracket and developing mark；Wherein, the current divider bracket includes left room disk, tap hole and right room disk, successively combines and forms an entirety；The developing mark is located at the junction of left room disk and tap hole and the junction of right room disk and tap hole；The left room disk and right room disk are respectively arranged with left room disk grid and right room disk grid, and the perpendicular relationship of central axis of plane and tap hole where left room disk grid, the central axis of plane and tap hole where right room disk grid is at an angle；The tap hole is surround by one group of polygonal mesh and is formed；The atrium, which shunts equipment surfaces, can coat the drug of one layer of inhibition endothelialization.
Description
Technical field
The present invention relates to the field of medical instrument technology, it is related to a kind of atrium part flow arrangement for mammalian heart, uses
In reduction atrium sinistrum high pressure, slow down heart failure symptoms.
Background technique
Heart failure (Heart failure, heart failure) is the final result and various heart abnormalities of various cardiovascular events
Cumulative effect, eventually lead to cardiac pumping function decline.Once there is the clinical manifestation of heart failure in cardiovascular patient, prompts prognosis
Difference.Heart failure is heavier, and mortality risk is higher.Heart failure is the abnormal change of cardiac function and structure caused by a variety of causes, makes ventricle
Contraction, which penetrates blood and (or) diastole and fills function, occurs obstacle, so as to cause one group of complex clinical syndrome, main performance is living
The decline (have difficulty in breathing, is tired) of dynamic tolerance and fluid retention (pulmonary venous pleonaemia, congestion of systemic circulation and periphery oedema).
Ejection fraction retain heart failure (Heart failure with preserved ejection fraction,
HFpEF, LVEF value >=50%) be heart failure a kind of common type, account for 50% or so of heart failure case.Epidemiology shows,
HFpEF disease incidence is in rising trend in the world.Currently, heart failure (the Heart failure reduced for ejection fraction
With reduced ejection fraction, HFrEF), it, can be effective using drugs such as heart tonifying, diuresis, medicament for expanding vascellum
Slow down the progress of this type heart failure deterioration.But there has been no the death that drug or instrument can substantially reduce HFpEF patient so far
Rate or in hospital risk.In addition, HFpEF is related to many complication, for its complicated Pathological Physiology, we know at present
It is few.HFpEF universals are that left atrial pressure increases (when especially moving), cause pulmonary hypertension, so as to cause pulmonary venous pleonaemia
And expiratory dyspnea.Expiratory dyspnea is the main reason for HFpEF patient is frequently hospitalized.Retrospective materials are shown, although lung when rest
Capillary wedge pressure (Pulmonary capillary wedge pressur, PCWP) normally, but move when PCWP it is significant on
It rises.This is related with 6min walking distance and long-term survival rate reduction.Therefore, PCWP when resting or move may be HFpEF
The therapy target of patient.
Therefore the purpose of the present invention is to provide a kind of atrium to shunt instrument, is implanted to the atrial septum position of HFpEF patient,
So that there is a hole in atrial septum position, to reduce left atrial pressure when HFpEF patient motion, to reduce pulmonary arterial pressure
Power and PCWP reduce the generation of pulmonary venous pleonaemia, reach the expiratory dyspnea that HFpEF patient is effectively relieved and the symptoms such as tired.
Summary of the invention
It is the general introduction for the theme that the present invention is described in detail below.This general introduction is not the protection in order to limit claim
Range.
The technical problem to be solved in the present invention is to provide one kind to be capable of fixing in atrial septum position, simultaneously long-term retaining hole is wide open
The atrium for putting state shunts instrument, and playing appropriateness reduces atrium sinistrum blood pressure, reduce left atria volume, slow down chronic heart failure disease
Shape improves left heart function and prevents the effect of left heart insufficiency.
The invention discloses the atrium that one kind can develop to shunt instrument, comprising: current divider bracket and developing mark；Wherein,
The current divider bracket includes left room disk, tap hole and right room disk, successively combines and forms an entirety；The developing mark
Positioned at the junction of the junction and right room disk and tap hole of left room disk and tap hole；The left room disk and right room
Disk is respectively arranged with left room disk grid and right room disk grid, the central axis of plane and tap hole where left room disk grid
The perpendicular relationship of line, the central axis of plane and tap hole where right room disk grid is at an angle；The tap hole is by one
Group polygonal mesh, which is surround, to be formed；The atrium, which shunts equipment surfaces, can coat the drug of one layer of inhibition endothelialization.
Selectively, the current divider bracket is at least one of superelastic alloy or shape memory alloy material, is swashed
Light is cut.
Selectively, the developing mark is at least one of platinum or platinum alloy, gold or billon, palladium or palldium alloy, with
Increase the atrium and shunts the X-ray perspective of instrument in human body.
Selectively, the number of the developing mark is 6 to 24.
Selectively, the developing mark passes through the process Installation inlayed to the left room disk root of the current divider bracket
With right room disk root.
Selectively, the quantity of the left room disk grid is 3 to 12.
Selectively, the maximum gauge range that the left room disk grid end is formed by circumscribed circle arrives for 12mm
25mm。
Selectively, the quantity of the right room disk grid is 3 to 12.
Selectively, the maximum gauge range that the right room disk grid end is formed by circumscribed circle arrives for 10mm
25mm。
Selectively, plane and the central axis institute angle degree range of tap hole are 0 where the right room disk grid
It spends to 90 degree.
Selectively, the diameter range of the tap hole is 6mm to 12mm.
Selectively, the altitude range of the tap hole is 2mm to 8mm.
Selectively, what the circumscribed circle and the right room disk grid end that the left room disk grid end is formed were formed
Circumscribed circle maximum gauge is 6mm at least bigger than the diameter of the tap hole.
Selectively, the polygonal mesh of the composition tap hole is diamond structure or hexagonal structure.
Selectively, the quantity of the polygonal mesh of the composition tap hole is 6 to 12.
Selectively, the atrium, which shunts equipment surfaces, can coat the drug of one layer of inhibition endothelialization, such as rapamycin,
Taxol etc..
It is an advantage of the invention that the atrium, which shunts instrument, to be implanted into human body by transcatheter mode, in implantation process
In, left room disk is first discharged, right room disk is then discharged, left room disk and right room disk is finally made to be clamped in atrial septum respectively
Two sides form atrial septal hole, and playing appropriateness reduces atrium sinistrum blood pressure, reduce left atria volume, slow down chronic heart failure
Symptom improves left heart function and prevents the effect of left heart insufficiency.
Detailed description of the invention
Fig. 1 is the schematic diagram main view that a kind of atrium of the invention shunts instrument；
Fig. 2 is the schematic diagram front view that a kind of atrium of the invention shunts instrument；
Fig. 3 A is a kind of expanded schematic diagram of atrium current divider bracket of the invention；
Fig. 3 B is the expanded schematic diagram of another atrium current divider bracket of the invention；
Fig. 3 C is the expanded schematic diagram of another atrium current divider bracket of the invention；
Fig. 4 A is the expanded schematic diagram of another atrium current divider bracket of the invention；
Fig. 4 B is the expanded schematic diagram of another atrium current divider bracket of the invention；
Fig. 4 C is the expanded schematic diagram of another atrium current divider bracket of the invention；
Fig. 5 A is the expanded schematic diagram of another atrium current divider bracket of the invention；
Fig. 5 B is the expanded schematic diagram of another atrium current divider bracket of the invention；
Fig. 5 C is the expanded schematic diagram of another atrium current divider bracket of the invention；
Fig. 6 is the schematic diagram that a kind of atrium of the invention shunts that instrument is implanted at atrial septum；
Specific embodiment
The present invention provides a kind of atrium shunting instrument, which forms a tap hole for implantation into atrial septum position,
And long-term retaining hole holes opened state, having reduces atrium sinistrum blood pressure, reduces left atria volume, slows down chronic heart failure disease
Shape improves the characteristics of left heart function and prevention left heart insufficiency.It is further below in conjunction with Figure of description and multiple embodiments
Illustrate technical solution of the present invention.
It is that the atrium that one kind of the invention can develop shunts the schematic diagram main view of instrument as shown in Figure 1.The atrium shunts
Instrument 100 includes: current divider bracket and developing mark 104；Wherein current divider bracket is by left room disk, tap hole 102 and right room
Disk successively combines and forms an entirety.The left room disk is made of multiple left room disk grids 101, the left room disk net
The number of lattice 101 is 3 to 12；The right room disk is made of multiple right room disk grids 103, the right room disk grid
103 number is 3 to 12.The developing mark is located at the junction of left room disk grid 101 and tap hole 102, and
The junction of right room disk grid 103 and tap hole 102.The current divider bracket and developing mark 104 are connected by mosaic mode
It connects.
The characteristics of developing mark 104 is to improve and shunt instrument 100 in X-ray with the postoperative atrium in art
Under see-through property, the implantation process of better guided operation, according to atrium shunt instrument design feature, selectively, institute
The number for stating developing mark 104 is 3 to 12, the material of the developing mark 104 be platinum or platinum alloy, gold or billon,
At least one of palladium or palldium alloy.
According to the relationship of left atrial pressure and flow, selectively, the diameter range of the tap hole 102 arrives for 6mm
12mm.Shunt the reduction degree that pore diameter size determines left atrial pressure and flow when different patient's implantable atrials shunt instrument.It can
Selectively, the altitude range of the tap hole is 2mm to 8mm.
It is the schematic diagram front view that a kind of atrium of the invention shunts instrument as shown in Figure 2.The left room disk grid 101
The perpendicular relationship of central axis of place plane and tap hole 102, selectively, the quantity of the left room disk grid 101 are 3
It is a to 12.It selectively, is 12mm by the maximum gauge range that 101 end of left room disk grid is formed by circumscribed circle
To 25mm.The central axis of the 101 place plane of left room disk grid and tap hole 102 at an angle, selectively, institute
Stating angular range is 0 degree to 90 degree.Selectively, the quantity of the left room disk grid 101 is 3 to 12.Selectively,
It is 12mm to 25mm by the maximum gauge range that 101 end of left room disk grid is formed by circumscribed circle.
The tap hole 102 is surround by one group of polygonal mesh 105 and is formed, as shown in Figure 2.Selectively, described polygon
Shape grid is diamond structure or hexagonal structure.
It is the expanded schematic diagram of atrium current divider bracket of the invention shown in Fig. 3 A, 3B, 3C, 4A, 4B, 4C, 5A, 5B and 5C
Various embodiments.The atrium current divider bracket is cut by laser by superelastic alloy or marmem pipe material,
The root of left room disk grid 101 and right room disk grid 103 is separately provided for inlaying the micropore of developing mark 104
1041。
Polygonal mesh structure 105 in atrium current divider bracket shown in Fig. 3 A- Fig. 3 C for forming tap hole is six sides
Shape network, stronger support force can be provided by being designed as hexagonal structure, and the hexagonal mesh structure is in single-row arrangement；
Polygonal mesh structure 105 in atrium current divider bracket shown in Fig. 4 A- Fig. 4 C for forming tap hole is network structure,
Design diamond structure is conducive to provide better heat treatment shaping ability, and the network structure is in single-row arrangement；Fig. 5 A- figure
Polygonal mesh structure 105 in the bracket of atrium current divider shown in 5C for forming tap hole is network structure, the water chestnut
Shape network is in multiple rows of arrangement, and being designed as multiple rows of diamond structure can guarantee that enough support forces and preferable heat treatment are fixed simultaneously
Type ability.Selectively, the quantity that the polygonal mesh of tap hole is formed described in circumferencial direction is 6 to 12.
Fig. 6 show a kind of atrium of the invention and shunts the schematic diagram that instrument is implanted to atrial septum position in human heart.The heart
Room shunts the intermediate position that instrument is implanted to atrial septum 203, and a channel is formed between atrium sinistrum 201 and atrium dextrum 202, from
And reaching reduces atrium sinistrum blood pressure, reduces left atria volume, slows down chronic heart failure symptom, improving left heart function and a prevention left side
The purpose of cardiac insufficiency.The left room disk grid 101 that atrium shunts instrument is close to the atrium sinistrum of atrial septum 203 after the implantation
The atrium dextrum side of atrial septum 203 is close in side, the end that atrium shunts the right room disk grid of instrument.The implantation of atrium current divider instrument
Behind atrial septum, over time, the tap hole 102 that atrium shunts instrument gradually may no longer be protected because of the endothelialization of cell
Hold unobstructed, even fully close, the function of disequilibrium left atrium pressure.Therefore, selectively, the atrium shunts instrument
Surface can coat the drug, such as rapamycin, taxol etc. of one layer of inhibition endothelialization.
The above embodiments are only used to illustrate the present invention, and not limitation of the present invention, in relation to the common of technical field
Technical staff can also make a variety of changes and modification without departing from the spirit and scope of the present invention, therefore all
Equivalent technical solution also belongs to scope of the invention, and scope of patent protection of the invention should be defined by the claims.
Claims (11)
1. the atrium that one kind can develop shunts instrument, comprising: current divider bracket and developing mark；Wherein, the current divider bracket
Including left room disk, tap hole and right room disk, successively combines and form an entirety；The developing mark be located at left room disk and
The junction of tap hole and the junction of right room disk and tap hole；The left room disk and right room disk are respectively arranged with
Left room disk grid and right room disk grid, the perpendicular relationship of central axis of plane and tap hole where left room disk grid,
The central axis of plane and tap hole where right room disk grid is at an angle；The tap hole is by one group of polygon latticed lattice ring
Around forming；The atrium, which shunts equipment surfaces, can coat the drug of one layer of inhibition endothelialization.
2. atrium according to claim 1 shunts instrument, it is characterized in that: the current divider bracket is superelastic alloy or shape
At least one of shape memory alloys material, is cut by laser.
3. atrium according to claim 1 shunts instrument, it is characterized in that: the developing mark is platinum or platinum alloy, Jin Huo
At least one of billon, palladium or palldium alloy shunts the X-ray perspective of instrument in human body to increase the atrium.
4. atrium according to claim 1 shunts instrument, it is characterized in that: the number of the developing mark is 6 to 24.
The developing mark passes through the process Installation inlayed to the left room disk root and right room disk root of the current divider bracket.
5. atrium according to claim 1 shunts instrument, arrived it is characterized in that: the quantity of the left room disk grid is 3
12.The maximum gauge range that the left room disk grid end is formed by circumscribed circle is 12mm to 25mm.
6. atrium according to claim 1 shunts instrument, arrived it is characterized in that: the quantity of the right room disk grid is 3
12.The maximum gauge range that the right room disk grid end is formed by circumscribed circle is 12mm to 25mm.
7. atrium according to claim 1 shunts instrument, it is characterized in that: plane and shunting where the right room disk grid
The central axis institute angle degree range in hole is 0 degree to 90 degree.
8. atrium according to claim 1 shunts instrument, it is characterized in that: left room disk grid end formation is external
The circumscribed circle maximum gauge that the round and described right room disk grid end is formed is 6mm at least bigger than the diameter of the tap hole.
9. atrium according to claim 1 shunts instrument, it is characterized in that: the diameter range of the tap hole arrives for 6mm
12mm.The altitude range of the tap hole is 2mm to 8mm.
10. atrium according to claim 1 shunts instrument, it is characterized in that: the polygonal mesh of the composition tap hole is
Diamond structure or hexagonal structure.
11. atrium according to claim 1 shunts instrument, it is characterized in that: the atrium, which shunts equipment surfaces, can coat one
Layer inhibits the drug of endothelialization, and the inhibition endothelialization drug is rapamycin or taxol.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811273350.XA CN109199470A (en) | 2018-10-30 | 2018-10-30 | A kind of atrium shunting instrument |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811273350.XA CN109199470A (en) | 2018-10-30 | 2018-10-30 | A kind of atrium shunting instrument |
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|---|---|
| CN109199470A true CN109199470A (en) | 2019-01-15 |
Family
ID=64997771
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811273350.XA Pending CN109199470A (en) | 2018-10-30 | 2018-10-30 | A kind of atrium shunting instrument |
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| CN (1) | CN109199470A (en) |
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| WO2020233523A1 (en) * | 2019-05-17 | 2020-11-26 | 先健科技(深圳)有限公司 | Implantable instrument and preparation method therefor |
| WO2020259492A1 (en) * | 2019-06-25 | 2020-12-30 | 杭州诺生医疗科技有限公司 | Atrial septostomy device |
| CN113397762A (en) * | 2021-05-31 | 2021-09-17 | 上海心瑞医疗科技有限公司 | Atrium shunting implantation device |
| CN114028623A (en) * | 2021-10-26 | 2022-02-11 | 江苏朴芃医疗科技有限公司 | Cardiac shunt |
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