CN109172693A - 用于调理宫寒和改善子宫虚寒的妇科凝胶 - Google Patents

用于调理宫寒和改善子宫虚寒的妇科凝胶 Download PDF

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CN109172693A
CN109172693A CN201811349996.1A CN201811349996A CN109172693A CN 109172693 A CN109172693 A CN 109172693A CN 201811349996 A CN201811349996 A CN 201811349996A CN 109172693 A CN109172693 A CN 109172693A
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潘龙高
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Guangxi Zhicheng Xiaoshan 131 Business And Trade Co Ltd
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Abstract

一种用于调理宫寒和改善子宫虚寒的妇科凝胶，包括：干鹿胎盘、当归、红参、益母草、龟甲、白术、地骨皮、熟地黄、丹参、菜菔子、桂肉、白酒、黄原胶，步骤包括：研磨、一次煎煮、二次煎煮、混合熬制，本发明产品具有补气养血、调经散寒、化瘀止痛之功效，对调补冲任、滋阴补阳、调节免疫力有着显著的效果。能有效改善气血不足，虚弱消瘦，精神疲倦，子宫虚寒，月经不调，经期腹痛的不良反应。

Description

用于调理宫寒和改善子宫虚寒的妇科凝胶
技术领域
本发明涉及妇科外用药技术领域，尤其涉及一种用于调理宫寒和改善子宫虚寒的妇科凝胶。
背景技术
中医认为：子宫内膜异位症归属于中医学痛经、不孕症、月经不调等病论治，病因主要与血瘀有关，血瘀是产生子宫内膜异位症的症状和体征的关键；冲任之脉因血瘀而功能失调，经络阻滞，隧道闭塞，冲任气血不通，故见痛经；宿瘀血结，日久不散，阻碍精卵相遇，故可导致不孕症；血瘀于内，新血不得归经，加痰浊内生，痰瘀互结所致月经不调、渐进性痛经、性交痛等症状。
中医中药治疗子宫内膜异位症，在解除症状的同时，身体的功能得到调整，并可使患者体质状况得到改善。由于中医药疗效好，毒副作用小，容易被患者所接受，因此寻求一种高效治疗子宫内膜异位症及痛经的药物是急待解决的问题。
发明内容
为此，本发明提供一种用于调理宫寒和改善子宫虚寒的妇科凝胶，用以克服现有技术中。的问题。
一方面，本发明提供一种用于调理宫寒和改善子宫虚寒的妇科凝胶，其特征在于，主料以重量份计包括：干鹿胎盘7-11份、当归3-5份、红参1-2份、益母草2-4份、龟甲1-3份、白术2-3份、地骨皮5-7份、熟地黄2-4份、丹参1-3份、菜菔子1-2份、桂肉2-3份、白酒13-15份、黄原胶6-8份。
优选地，主料以重量份计包括：干鹿胎盘9份、当归4.2份、红参1.6份、益母草3份、龟甲1.8份、白术2.6份、地骨皮6份、熟地黄3份、丹参2.1份、菜菔子1.4份、桂肉2.3份、白酒14份、黄原胶7份。
另一方面，本发明提供一种用于调理宫寒和改善子宫虚寒的妇科凝胶的制备方法，包括步骤研磨、一次煎煮、二次煎煮、混合熬制；其特征在于，所述一次煎煮，步骤包括：
A1将干鹿胎盘、当归、龟甲、白术，与前述物质总质量0.07-0.12％的茶多酚、总质量(2-2.5)倍的水混合均匀后，于78-98℃条件下微波煎煮1-2h；
A2将红参、益母草、地骨皮、桂肉，与前述物质总质量0.02-0.07％的茶多酚、总质量(2-2.5)倍的水混合均匀后，于65-88℃条件下微波煎煮1-2h；
A3将熟地黄、丹参、菜菔子，与前述物质总质量(1.2-1.7)倍的水混合均匀后，于57-79℃条件下微波煎煮1-1.5h。
进一步地，所述研磨包括：称取上述重量份干鹿胎盘、当归、红参、益母草、龟甲、白术、地骨皮、熟地黄、丹参、菜菔子、桂肉，分别用温度为43-47℃的微波辐射8-12min，然后分别置于中药粉碎机打磨成粉状。
进一步地，所述二次煎煮包括：将一次煎煮所得固形物合并，加入总质量1.3-1.5倍的水，置于温度为100-120℃条件下微波煎煮30-45min。
进一步地，所述混合熬制包括：合并一次煎煮液及二次煎煮液，并加入白酒、黄原胶混合均匀，用文火煎熬浓缩至膏状物，冷却即得。
与现有技术相比，本发明的有益效果在于，本发明产品具有补气养血、调经散寒、化瘀止痛之功效，对调补冲任、滋阴补阳、调节免疫力有着显著的效果。能有效改善气血不足，虚弱消瘦，精神疲倦，子宫虚寒，月经不调，经期腹痛的不良反应。
进一步地本发明产品制造方法中添加茶多酚对鹿胎盘和其他中药材进行处理，可起到去除异味，增加可吸收钙质、活血化瘀和引药入经、增强疗效的作用。采用微波煎煮的方法将主料成粉煎煮，可确保主料中各种有效成分不丢失，包括鹿胎盘内在的活性物质不被长时间高温加热所破坏，功效得以提高；利用白酒和黄原胶还具有延长产品的保质期。
进一步地，本发明产品增加了当归、红参、益母草、龟甲、白术、地骨皮、熟地黄、丹参、菜菔子、桂肉等组分，其中，当归具有补血和血，调经止痛，润燥滑肠之功效；红参具有补元气、补脾肺、生津安神、益气摄血之功效；益母草具有活血调经，利尿消肿之功效；龟甲滋阴潜阳，益肾强骨，养血补心之功效；白术具有健脾益气，燥湿利水，止汗，安胎之功效；地骨皮具有滋补肝肾，益精明目之功效；熟地黄具有滋阴，补血之功效；丹参具有祛瘀止痛，活血通经，清心除烦之功效；菜菔子具有顺气通便，消食除胀，降气化痰之功效；桂肉具有益心脾，补气血之功效；这些组分与干鹿胎组分相配伍，既保留并提高了用于调理宫寒和改善子宫虚寒的妇科凝胶的滋补功效，又增加了对内分泌失调、子宫内膜异位症等疾病有防治作用，疾病预防和滋补强身两种功效相辅相成、相得益彰，功效发挥快。
具体实施方式
为了使本发明的目的和优点更加清楚明白，下面结合实施例对本发明作进一步描述；应当理解，此处所描述的具体实施例仅用于解释本发明，并不用于限定本发明。
实施例1
本实施例提供了一种用于调理宫寒和改善子宫虚寒的妇科凝胶，主料包括：干鹿胎盘9份、当归4.2份、红参1.6份、益母草3份、龟甲1.8份、白术2.6份、地骨皮6份、熟地黄3份、丹参2.1份、菜菔子1.4份、桂肉2.3份、白酒14份、黄原胶7份。
实施例2
本实施例提供了一种用于调理宫寒和改善子宫虚寒的妇科凝胶，主料包括：干鹿胎盘11份、当归5份、红参2份、益母草4份、龟甲3份、白术3份、地骨皮7份、熟地黄4份、丹参3份、菜菔子1-2份、桂肉3份、白酒15份、黄原胶8份。
实施例3
本实施例提供了一种用于调理宫寒和改善子宫虚寒的妇科凝胶，主料包括：干鹿胎盘7份、当归3份、红参1份、益母草2份、龟甲1份、白术2份、地骨皮5份、熟地黄2份、丹参1份、菜菔子1-2份、桂肉2份、白酒13份、黄原胶6份。
实施例4
本实施例提供了一种用于调理宫寒和改善子宫虚寒的妇科凝胶，主料包括：干鹿胎盘9份、当归4份、红参1.5份、益母草3份、龟甲2份、白术2.5份、地骨皮6份、熟地黄3份、丹参2份、菜菔子1.5份、桂肉2.5份、白酒14份、黄原胶7份。
实施例5
本实施例提供了一种用于调理宫寒和改善子宫虚寒的妇科凝胶，主料包括：干鹿胎盘6.9份、当归2.9份、红参0.9份、益母草1.9份、龟甲0.9份、白术1.9份、地骨皮4.9份、熟地黄1.9份、丹参0.9份、菜菔子0.9份、桂肉1.98份、白酒12.5份、黄原胶5.9份。
实施例6
本实施例提供了一种用于调理宫寒和改善子宫虚寒的妇科凝胶，主料包括：干鹿胎盘12份、当归6份、红参3份、益母草5份、龟甲4份、白术4份、地骨皮8份、熟地黄5份、丹参4份、菜菔子3份、桂肉4份、白酒16份、黄原胶9份。
实施例7-12
实施例7-12分别在实施例1-6的基础上提供了用于调理宫寒和改善子宫虚寒的妇科凝胶的制作方法，包括如下步骤：
A研磨：称取上述重量份干鹿胎盘、当归、红参、益母草、龟甲、白术、地骨皮、熟地黄、丹参、菜菔子、桂肉，分别用温度为45℃的微波辐射10min，然后分别置于中药粉碎机打磨成粉状；
B一次煎煮：二次煎煮、混合熬制；所述一次煎煮，步骤包括：
B1将干鹿胎盘、当归、龟甲、白术，与前述物质总质量0.09％的茶多酚、总质量2倍的水混合均匀后，于88℃条件下微波煎煮1-2h；
B2将红参、益母草、地骨皮、桂肉，与前述物质总质量0.05％的茶多酚、总质量2.5倍的水混合均匀后，于75℃条件下微波煎煮1-2h；
B3将熟地黄、丹参、菜菔子，与前述物质总质量1.5倍的水混合均匀后，于63℃条件下微波煎煮1.2h；
C二次煎煮：将一次煎煮所得固形物合并，加入总质量1.4倍的水，置于温度为110℃条件下微波煎煮37min；
D混合熬制：合并一次煎煮液及二次煎煮液，并加入白酒、黄原胶混合均匀，用文火煎熬浓缩至膏状物，冷却，即得鹿胎盘膏。
试验例1
药效学实验
分为实验组1-6和对照组，各组15例患者；实验组1-6分别于月经前10天在肚子上涂抹分发明所述凝胶，对照组于月经前10天给予市售鹿胎盘膏，连续用10日，3个月经周期，经期停用，实验组1-6和对照组的痛经症状评分如表1所示：
表1
组别 显效(例) 有效(例) 无效(例) 总有效率(％)
对照组 0 3 12 20.00％
实验组1 6 8 1 93.33％
实验组2 7 6 2 86.67％
实验组3 3 8 4 73.33％
实验组4 4 9 2 86.67％
实验组5 0 5 10 33.33％
实验组6 1 6 8 46.67％
本试验例选取最优剂量、高剂量、低剂量、剂量范围外的配方组进行试验对比，其中剂量范围外的配方组(如实验组5和实验组6)相比与实验组1-4，其效果较差，同时，本申请人还进行不加入当归、红参、益母草、龟甲、白术、地骨皮、熟地黄、丹参、菜菔子、桂肉中任一种成分制作，并进行了对比试验，其总有效率约在10.00-25.00％左右，均没有本发明提供的配方药效好。
以上所述仅为本发明的优选实施例，并不用于限制本发明；对于本领域的技术人员来说，本发明可以有各种更改和变化。凡在本发明的精神和原则之内，所作的任何修改、等同替换、改进等，均应包含在本发明的保护范围之内。

Claims (6)

1.一种用于调理宫寒和改善子宫虚寒的妇科凝胶，其特征在于，主料以重量份计包括：干鹿胎盘7-11份、当归3-5份、红参1-2份、益母草2-4份、龟甲1-3份、白术2-3份、地骨皮5-7份、熟地黄2-4份、丹参1-3份、菜菔子1-2份、桂肉2-3份、白酒13-15份、黄原胶6-8份。
2.根据权利要求1所述的用于调理宫寒和改善子宫虚寒的妇科凝胶，其特征在于，主料以重量份计包括：干鹿胎盘9份、当归4.2份、红参1.6份、益母草3份、龟甲1.8份、白术2.6份、地骨皮6份、熟地黄3份、丹参2.1份、菜菔子1.4份、桂肉2.3份、白酒14份、黄原胶7份。
3.根据权利要求1或2所述用于调理宫寒和改善子宫虚寒的妇科凝胶的制备方法，包括步骤研磨、一次煎煮、二次煎煮、混合熬制；其特征在于，所述一次煎煮，步骤包括：
A1将干鹿胎盘、当归、龟甲、白术，与前述物质总质量0.07-0.12％的茶多酚、总质量(2-2.5)倍的水混合均匀后，于78-98℃条件下微波煎煮1-2h；
A2将红参、益母草、地骨皮、桂肉，与前述物质总质量0.02-0.07％的茶多酚、总质量(2-2.5)倍的水混合均匀后，于65-88℃条件下微波煎煮1-2h；
A3将熟地黄、丹参、菜菔子，与前述物质总质量(1.2-1.7)倍的水混合均匀后，于57-79℃条件下微波煎煮1-1.5h。
4.根据权利要求3所述用于调理宫寒和改善子宫虚寒的妇科凝胶的制备方法，其特征在于，所述研磨包括：称取上述重量份干鹿胎盘、当归、红参、益母草、龟甲、白术、地骨皮、熟地黄、丹参、菜菔子、桂肉，分别用温度为43-47℃的微波辐射8-12min，然后分别置于中药粉碎机打磨成粉状。
5.根据如权利要求3所述的用于调理宫寒和改善子宫虚寒的妇科凝胶的制备方法，其特征在于，所述二次煎煮包括：将一次煎煮所得固形物合并，加入总质量1.3-1.5倍的水，置于温度为100-120℃条件下微波煎煮30-45min。
6.根据权利要求3所述的用于调理宫寒和改善子宫虚寒的妇科凝胶的制备方法，其特征在于，所述混合熬制包括：合并一次煎煮液及二次煎煮液，并加入白酒、黄原胶混合均匀，用文火煎熬浓缩至膏状物，冷却即得。
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