CN109163954A - A kind of pathological diagnosis devices and methods therefor - Google Patents
A kind of pathological diagnosis devices and methods therefor Download PDFInfo
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- CN109163954A CN109163954A CN201811211987.6A CN201811211987A CN109163954A CN 109163954 A CN109163954 A CN 109163954A CN 201811211987 A CN201811211987 A CN 201811211987A CN 109163954 A CN109163954 A CN 109163954A
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- 238000010827 pathological analysis Methods 0.000 title claims abstract description 29
- 238000000034 method Methods 0.000 title abstract description 14
- 238000003745 diagnosis Methods 0.000 claims description 24
- 238000004043 dyeing Methods 0.000 claims description 20
- 238000002604 ultrasonography Methods 0.000 claims description 17
- 238000005286 illumination Methods 0.000 claims description 11
- 238000006073 displacement reaction Methods 0.000 claims description 10
- 238000010186 staining Methods 0.000 claims description 10
- 238000003672 processing method Methods 0.000 claims description 9
- 230000005611 electricity Effects 0.000 claims description 7
- 238000002405 diagnostic procedure Methods 0.000 claims description 6
- 238000002525 ultrasonication Methods 0.000 claims description 2
- 230000005855 radiation Effects 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 238000004458 analytical method Methods 0.000 abstract description 2
- 238000010586 diagram Methods 0.000 description 6
- 201000010099 disease Diseases 0.000 description 6
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 6
- 206010028980 Neoplasm Diseases 0.000 description 3
- 244000309464 bull Species 0.000 description 2
- 238000006243 chemical reaction Methods 0.000 description 2
- 230000007547 defect Effects 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 230000010354 integration Effects 0.000 description 2
- 241000237858 Gastropoda Species 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 210000000080 chela (arthropods) Anatomy 0.000 description 1
- 230000009089 cytolysis Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 235000013399 edible fruits Nutrition 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 238000010562 histological examination Methods 0.000 description 1
- 238000003384 imaging method Methods 0.000 description 1
- 238000007689 inspection Methods 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 230000004060 metabolic process Effects 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000002265 prevention Effects 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/28—Preparing specimens for investigation including physical details of (bio-)chemical methods covered elsewhere, e.g. G01N33/50, C12Q
- G01N1/30—Staining; Impregnating ; Fixation; Dehydration; Multistep processes for preparing samples of tissue, cell or nucleic acid material and the like for analysis
- G01N1/31—Apparatus therefor
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/17—Systems in which incident light is modified in accordance with the properties of the material investigated
- G01N21/25—Colour; Spectral properties, i.e. comparison of effect of material on the light at two or more different wavelengths or wavelength bands
- G01N21/31—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry
- G01N21/35—Investigating relative effect of material at wavelengths characteristic of specific elements or molecules, e.g. atomic absorption spectrometry using infrared light
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N21/00—Investigating or analysing materials by the use of optical means, i.e. using sub-millimetre waves, infrared, visible or ultraviolet light
- G01N21/84—Systems specially adapted for particular applications
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N29/00—Investigating or analysing materials by the use of ultrasonic, sonic or infrasonic waves; Visualisation of the interior of objects by transmitting ultrasonic or sonic waves through the object
- G01N29/04—Analysing solids
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- Investigating Or Analysing Materials By Optical Means (AREA)
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Abstract
The present invention relates to a kind of pathological diagnosis devices and methods therefors, escape aperture is offered in support plate, the lower part of support plate is provided with rehandling facilities, the top of support plate is provided with shifting apparatus, controller is fixedly installed on bottom plate, the side of controller is connected with deduster, and the control plate face being connected with controller is fixedly installed on top plate, and the side for controlling plate face is fixedly installed with electron microscope；The full-automatic reprinting and transfer operation being sliced from after acquisition are realized, the pollution of slice is avoided, efficient quickly reprinting and transfer operation, the diagnostic analysis once to walk is realized and provides guarantee.
Description
Technical field
The present invention relates to medical fields, and in particular to a kind of pathological diagnosis devices and methods therefor.
Background technique
Pathological diagnosis is operation to be cut or is autopsied the tumor specimen removed, after fixed dyeing, under the microscope into
Row histological examination, to diagnose the illness.Pathological diagnosis is the reason of study of disease occurs, in pathogenesis and lysis
The morphosis of sickened body, functional metabolism change are lapsed to disease, to be the diagnosis of disease, treatment, prevention provides must
The theoretical basis and practical basis wanted.Pathological diagnosis before the treatment, is taken, cut off or cut with pincers with living person
Method obtains tumor tissues and carries out pathological diagnosis under the microscope after fixed dyeing.Although various Imaging Technologies are rapidly sent out
Exhibition, but pathological diagnosis be still it is most reliable in the various inspection methods of tumour, pathological diagnosis is called " goldstandard " and disease
The last diagnostic of disease.
Traditional pathological diagnosis does not have a dedicated automation equipment, slice from after obtaining, need multiple steps transfer and
It reprints, in this course, often will appear misoperation, lead to the pollution of slice, influence the analyzing and diagnosing knot of next step
Fruit.And at present also without special pathological diagnosis operating system or device, single pathological diagnosis equipment can be only done one kind
Pathological diagnosis operation is not able to satisfy multistation or the conversion between multistation, generally requires to carry out between multiple devices comprehensive
Cooperation processing is closed, occur transfer unavoidably and reprints operation, has seriously affected the efficiency of pathological diagnosis.Between a variety of diagnostic devices
Conversion process also increases workload, or even increases the occupied area of equipment, also pays no attention to and manages and maintains.
Therefore it provides a kind of structure is simple, easy to operate, work efficiency is high, saves human resources, safe and efficient, reduces
Operating time and step reduce pollution risk, and occupied area is small, and integration capability is strong, the simple and fast pathological diagnosis device of method
And its method, there are extensive market prospects.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides that a kind of structure is simple, and easy to operate, work efficiency is high, saves people
Power resource, it is safe and efficient, operating time and step are reduced, pollution risk is reduced, occupied area is small, and integration capability is strong, method letter
Single efficiently pathological diagnosis devices and methods therefor, for overcoming defect in the prior art.
The technical scheme of the present invention is realized as follows: a kind of pathological diagnosis device, including bottom plate, pass through four support rods
It is mounted on the top plate on bottom plate top, the intermediate support plate between top plate and bottom plate is set, it is characterised in that: the support plate
On offer escape aperture, the lower part of support plate is provided with rehandling facilities, the top of support plate is provided with shifting apparatus, bottom plate
On be fixedly installed with controller, the side of controller is connected with deduster, is fixedly installed on top plate and is connected with controller
Control plate face, the side for controlling plate face is fixedly installed with electron microscope.
The rehandling facilities includes the reprinting seat being arranged in below escape aperture, and the bottom for reprinting seat is movably installed with first
Electric pushrod is fixedly installed with first motor in the side for reprinting seat, and the output end of first motor is fixedly installed with turbine, the
The side of one motor is fixedly installed with the second motor, and the output end of the second motor is fixedly installed with rotating wheel, rotating wheel and rotation
Bar is fixedly connected, and swingle is connected by bearing with rotary shaft, and fixing sleeve is equipped with the snail matched with turbine on the rotary shaft
Rod sleeve is equipped with disposable pallet in the end of rotary shaft, and the shifting apparatus includes being fixedly mounted on escape aperture top
Displacement looking for flat in the support plate of side is displaced in looking for flat and is fixedly installed with the second electric pushrod, is arranged on the supporting plate
There is the third electric pushrod opposite with the outbound course of the second electric pushrod, is fixedly mounted in the output end of the second electric pushrod
There is the first push plate, the second push plate is fixedly installed in the output end of third electric pushrod, between the first push plate and the second push plate
Support plate be fixedly installed with the 4th electric pushrod, the 5th electric pushrod and the 6th electric pushrod, the 4th electric pushrod, the 5th
The outbound course of the outbound course and the second electric pushrod and third electric pushrod of electric pushrod and the 6th electric pushrod is mutual
Vertically, the corresponding position of side above escape aperture is arranged in the 4th electric pushrod, in the 4th electric pushrod maximum output position
Top is fixedly installed with dyeing liquor efferent duct, is provided with red infrared illumination light above the 5th electric pushrod maximum output position,
It is provided with ultrasound reactor below the 6th electric pushrod maximum output position, in the second electric pushrod maximum output position
Top be provided with the observation port being connected with electron microscope.
Four corner locations of the intermediate support plate are fixedly connected with four support rods, intermediate support plate, bottom plate with
And the top plate on top is rectangle tabular structure, is fixedly connected at the top of the bottom of controller and bottom plate, deduster is by leading
Line is connected with controller, is fixedly connected at the top of the bottom of deduster and bottom plate, is fixedly installed with and removes on the outside of deduster
Dirt net is provided with battery main switch, staining pattern switch, ultrasonication mode switch and infrared processing mould in control plate face
Formula switch.
The escape aperture is rectangle cavernous structure, and reprinting seat is U-shaped Cao Zhuan structure, reprints seat and escape aperture is vertical
It is corresponding, the length and width of seat is reprinted no more than the length and width with escape aperture, is fixedly installed with bottom reprinting seat bottom
Portion's push plate is equipped with sample collecting board in the top movable for reprinting seat internal backplane, and the bottom surface of bottom push plate electronic is pushed away with first
The top surface of bar is fixedly connected, and the bottom surface of the first electric pushrod is fixedly connected with the top surface of bottom plate, and the stroke of the first electric pushrod is not
Less than the distance of bottom push plate bottom surface to escape aperture top surface.
The reprinting seat and disposable pallet equal length are distributed in the two sides of the shaft core position of first motor, disposably
Pallet is rectangle groove-like structure, and the length and width for reprinting seat is not less than the length and width of disposable pallet, disposable to hold in the palm
The center line of disk to the distance between the center line of first motor with reprint seat center line between the center line of first motor
It is equidistant, turbine and worm screw axle sleeve equal length are distributed in the two sides of the second electrical axis position, water locating for turbine top surface
Horizontal plane locating for plane and worm screw axle sleeve bottom surface is same plane, and the end of rotary shaft is by movable bolt connector and disposably
Pallet is connected, and first motor is fixedly connected by first motor bracket with bottom plate.
The displacement looking for flat is rectangle tabular structure, is displaced the length of looking for flat and the equal length of support plate,
The width for being displaced looking for flat is not more than the width of support plate, the outbound course of the second electric pushrod and third electric pushrod on the contrary,
And the inside edge position of the second push plate mutually suits with displacement looking for flat inside edge position.
First electric pushrod, first motor, the second motor, the second electric pushrod, third electric pushrod, the 4th electricity
Dynamic push rod, the 5th electric pushrod and the 6th electric pushrod, red infrared illumination light and ultrasound reactor pass through conducting wire and control
Device processed is connected, and controller is connected by conducting wire with control plate face, and first motor passes through first motor support rod and support plate
It is connected.
A kind of diagnostic method of pathological diagnosis device as described above, which is characterized in that its diagnostic method is as follows: existing first
Under equipment original state, control plate face opens equipment power supply, and disposable pallet initial position is located at the whole outside position of equipment at this time
It sets, the sample to be diagnosed being collected is thrown in disposable pallet, and by control plate face running equipment, there are three types of examine equipment
Disconnected mode, respectively Staining for Diagnosis mode, ultrasonic response diagnostic mode and infrared processing diagnostic mode pass through control plate face choosing
It selects one of diagnostic mode and carries out processing operation；
The processing method of Staining for Diagnosis mode are as follows: the rotation of the second motor operation drives rotating wheel rotation, and rotating wheel drives rotation
Bar, bearing, rotary shaft, worm screw axle sleeve and disposable pallet rotate 180 degree, reprint position at the top of seat when disposable pallet turns to
When setting, the second motor is out of service, and worm screw axle sleeve is engaged with turbine at this time, and first motor brings into operation, and worm screw axle sleeve rotates simultaneously
Rotary shaft rotation is driven, rotary shaft drives disposable pallet to rotate 180 degree, and sample to be diagnosed is launched to reprinting in seat, once
Property pallet reset, the first electric pushrod is run at this time, is driven and is reprinted seat and move upwards across escape aperture, will be reprinted seat and be reprinted to the
Four output end of electric push rod corresponding positions are simultaneously out of service, at this time the 4th electric pushrod run, will sample be diagnosed from reprint seat
In be pushed out to below dyeing liquor efferent duct, the 4th electric pushrod and the first electric pushrod are resetted in succession, are exported by dyeing liquor
Pipe treats diagnosis sample and carries out dyeing processing, and the second electric pushrod starting operation, the sample to be diagnosed after dyeing is pushed away after dyeing
It moves to below observation port, diagnosis is observed to it by electron microscope, and obtain diagnostic result；
The processing method of ultrasonic response diagnosis mould are as follows: the rotation of the second motor operation drives rotating wheel rotation, and rotating wheel drives rotation
Bull stick, bearing, rotary shaft, worm screw axle sleeve and disposable pallet rotate 180 degree, reprint at the top of seat when disposable pallet turns to
When position, the second motor is out of service, and worm screw axle sleeve is engaged with turbine at this time, and first motor brings into operation, the rotation of worm screw axle sleeve
And rotary shaft is driven to rotate, and rotary shaft drives disposable pallet to rotate 180 degree, and sample to be diagnosed is launched into reprinting seat, and one
Secondary property pallet resets, and the first electric pushrod is run at this time, drives and reprints seat and move upwards across escape aperture, will reprint seat reprint to
4th output end of electric push rod corresponding position is simultaneously out of service, and third electric pushrod is run at this time, will reprint seat and elapses to the 6th
It after electric pushrod corresponding position and resets, the first electric pushrod resets simultaneously, and the 6th electric pushrod is run at this time, will reprint seat and moves
It is loaded above ultrasound reactor, the sample to be diagnosed reprinted in seat is carried out at ultrasound reactor by ultrasound reactor
Reason, after processing, the second electric pushrod starting operation, seat to be reprinted is elapsed to below observation port, by electron microscope to its into
Row observation diagnosis, and obtain diagnostic result；
The processing method of infrared processing diagnostic mode are as follows: the rotation of the second motor operation drives rotating wheel rotation, and rotating wheel drives rotation
Bull stick, bearing, rotary shaft, worm screw axle sleeve and disposable pallet rotate 180 degree, reprint at the top of seat when disposable pallet turns to
When position, the second motor is out of service, and worm screw axle sleeve is engaged with turbine at this time, and first motor brings into operation, the rotation of worm screw axle sleeve
And rotary shaft is driven to rotate, and rotary shaft drives disposable pallet to rotate 180 degree, and sample to be diagnosed is launched into reprinting seat, and one
Secondary property pallet resets, and the first electric pushrod is run at this time, drives and reprints seat and move upwards across escape aperture, will reprint seat reprint to
4th output end of electric push rod corresponding position is simultaneously out of service, and third electric pushrod is run at this time, will reprint seat and elapses to the 5th
It after electric pushrod corresponding position and resets, the first electric pushrod resets simultaneously, and the 5th electric pushrod is run at this time, will reprint seat and moves
It is loaded onto below red infrared illumination light, ultrasound reactor processing is carried out to the sample to be diagnosed reprinted in seat by red infrared illumination light,
After processing, the second electric pushrod starting operation, seat to be reprinted is elapsed to observation port, is seen by electron microscope to it
Diagnosis is surveyed, and obtains diagnostic result.
The present invention has following good effect: firstly, this product structure is simple, it is easy to operate, overcome traditional disease
Reason diagnoses the defect of no dedicated automation equipment, realizes full-automatic reprinting and transfer operation of the slice from after obtaining, keeps away
The pollution for having exempted from slice, realizes efficiently quickly reprinting and transfer operation, the diagnostic analysis once to walk provide guarantee；Its
It is secondary, it avoids conventional multistep transfer and reprints the complicated processes in step, using full-automatic accurate processing, provide special
Diagnostic mode device that can be single can be integrated, Staining for Diagnosis mode can be completed using an equipment, ultrasonic response diagnoses
Switching between mode and infrared processing diagnostic mode realizes multi-mode and multistation operation processing, avoids intermediate steps
The faulty operation of appearance is conducive to the efficiency for improving diagnosis, saves the time of diagnosis, alleviate the work of personnel, integrally set
Standby occupied area is reduced, and be also beneficial to the later period manages and maintains operation；Again, this product method has simply operated, and one
Keyed operation, and rehandling facilities and shifting apparatus are separately handled, it is independent of each other, guarantees to reprint steady with each side in transfer step
It is qualitative, there is good social and economic benefit.
Detailed description of the invention
Fig. 1 is schematic view of the front view of the invention.
Fig. 2 is side structure schematic diagram of the invention.
Fig. 3 is one of using state structure diagram of the invention.
Fig. 4 is the two of using state structure diagram of the invention.
Fig. 5 is the three of using state structure diagram of the invention.
Fig. 6 is control plate face structural schematic diagram of the invention.
Fig. 7 is the second motor connecting structure schematic diagram of the invention.
Specific embodiment
As shown in Fig. 1,2,3,4,5,6,7, a kind of pathological diagnosis device, including bottom plate 1, it is installed by four support rods 5
Top plate 2 on 1 top of bottom plate is arranged in the intermediate support plate 3 between top plate 2 and bottom plate 1, offers in the support plate 3
Escape aperture 4 is provided with rehandling facilities in the lower part of support plate 3, and the top of support plate 3 is provided with shifting apparatus, consolidates on bottom plate 1
Dingan County is equipped with controller 22, and the side of controller 22 is connected with deduster 23, is fixedly installed on top plate 2 and 22 phase of controller
The side of the control plate face 37 of connection, control plate face 37 is fixedly installed with electron microscope 36.
The rehandling facilities includes the reprinting seat 20 being arranged in below escape aperture 4, reprints the bottom activity installation of seat 20
There is the first electric pushrod 18, is fixedly installed with first motor 16 in the side for reprinting seat 20, the output end of first motor 16 is fixed
Turbine 17 is installed, is fixedly installed with the second motor 6 in the side of first motor 16, the output end of the second motor 6 is fixedly mounted
There is rotating wheel 8, rotating wheel 8 is fixedly connected with swingle 10, and swingle 10 is connected by bearing 9 with rotary shaft 11, is being rotated
Fixing sleeve is equipped with the worm screw axle sleeve 12 matched with turbine 17 on axis 11, is equipped with disposable pallet in the end of rotary shaft 11
14, the shifting apparatus includes the displacement looking for flat 38 being fixedly mounted in the support plate 3 of 4 top side of escape aperture, displacement
It is fixedly installed with the second electric pushrod 25 in looking for flat 38, the output with the second electric pushrod 25 is provided in support plate 3
Contrary third electric pushrod 27 is fixedly installed with the first push plate 26 in the output end of the second electric pushrod 25, in third
The output end of electric pushrod 27 is fixedly installed with the second push plate 28, the support plate 3 between the first push plate 26 and the second push plate 28
It is fixedly installed with the 4th electric pushrod 29, the 5th electric pushrod 30 and the 6th electric pushrod 31, the 4th electric pushrod the 29, the 5th
The output of the outbound course and the second electric pushrod 25 and third electric pushrod 27 of electric pushrod 30 and the 6th electric pushrod 31
Direction is mutually perpendicular to, and the corresponding position of 4 top side of escape aperture is arranged in the 4th electric pushrod 29, the 4th electric pushrod 29 most
The top of big output position is fixedly installed with dyeing liquor efferent duct 34, sets above 30 maximum output position of the 5th electric pushrod
It is equipped with red infrared illumination light 32, is provided with ultrasound reactor 33 below 31 maximum output position of the 6th electric pushrod,
Two electric pushrods is provided with the observation port 35 being connected with electron microscope 36 above 25 maximum output position.
Four corner locations of the intermediate support plate 3 are fixedly connected with four support rods 5, intermediate support plate 3, bottom plate
1 and the top plate 2 on top be rectangle tabular structure, the bottom of controller 22 is fixedly connected with the top of bottom plate 1, deduster
23 are connected by conducting wire with controller 22, and the bottom of deduster 23 is fixedly connected with the top of bottom plate 1, in the outer of deduster 23
Side is fixedly installed with basket strainer 24, battery main switch 39, staining pattern switch 40 is provided in control plate face 37, at ultrasonic wave
Manage mode switch 41 and infrared tupe switch 42.
The escape aperture 4 is rectangle cavernous structure, and reprinting seat 20 is U-shaped Cao Zhuan structure, reprints seat 20 and leaks out
Hole 4 is vertically corresponding, reprints the length and width of seat 20 no more than the length and width with escape aperture 4, is reprinting 20 bottom of seat
It is fixedly installed with bottom push plate 19, sample collecting board 21, bottom push plate are installed in the top movable for reprinting 20 internal backplane of seat
19 bottom surface is fixedly connected with the top surface of the first electric pushrod 18, and the bottom surface of the first electric pushrod 18 and the top surface of bottom plate 1 are fixed
Connection, the stroke of the first electric pushrod 18 are not less than the distance of 19 bottom surface of bottom push plate to 4 top surface of escape aperture.The reprinting seat
20 and 14 equal length of disposable pallet be distributed in first motor 16 shaft core position two sides, disposable pallet 14 be rectangle
Groove-like structure, the length and width for reprinting seat 20 is not less than the length and width of disposable pallet 14, in disposable pallet 14
Heart line to the distance between the center line of first motor 16 with reprint 20 center line of seat between the center line of first motor 16
It is equidistant, turbine 17 and 12 equal length of worm screw axle sleeve are distributed in the two sides of 6 shaft core position of the second motor, 17 top surface institute of turbine
Horizontal plane locating for the horizontal plane at place and 12 bottom surface of worm screw axle sleeve is same plane, and the end of rotary shaft 11 is bolted by movable screw
First 13 are connected with disposable pallet 14, and first motor 16 is fixedly connected by first motor bracket 7 with bottom plate 1.The position
Shifting looking for flat 38 is rectangle tabular structure, is displaced the length of looking for flat 38 and the equal length of support plate 3, is displaced looking for flat 38
Width be not more than the width of support plate 3, the outbound course of the second electric pushrod 25 and third electric pushrod 27 is on the contrary, and the
The inside edge position of two push plates 28 mutually suits with displacement 38 inside edge position of looking for flat.First electric pushrod
18, first motor 16, the second motor 6, the second electric pushrod 25, third electric pushrod 27, the 4th electric pushrod the 29, the 5th are electronic
Push rod 30 and the 6th electric pushrod 31, red infrared illumination light 32 and ultrasound reactor 33 pass through conducting wire and 22 phase of controller
Connection, controller 22 are connected by conducting wire with control plate face 37, and first motor 16 passes through first motor support rod 15 and support
Plate 3 is connected.
Embodiment 1: a kind of diagnostic method of pathological diagnosis device as described above, diagnostic method are as follows: setting first
Under standby original state, control plate face 37 opens equipment power supply, and disposable 14 initial position of pallet is located at the whole outside of equipment at this time
The sample to be diagnosed being collected is thrown in disposable pallet 14 by position, and by control 37 running equipment of plate face, equipment has
Three kinds of diagnostic modes, respectively Staining for Diagnosis mode, ultrasonic response diagnostic mode and infrared processing diagnostic mode, pass through control
Plate face 37 selects one of diagnostic mode to carry out processing operation；
As shown in Fig. 1,2,3,4,5, the processing method of Staining for Diagnosis mode are as follows: the operation rotation of the second motor 6 drives rotating wheel 8
Rotation, rotating wheel 8 drive swingle 10, bearing 9, rotary shaft 11, worm screw axle sleeve 12 and disposable pallet 14 to rotate 180 degree,
When disposable pallet 14, which turns to, reprints 20 top position of seat, the second motor 6 is out of service, at this time worm screw axle sleeve 12 and turbine
17 engagements, first motor 16 bring into operation, and worm screw axle sleeve 12 rotates and rotary shaft 11 is driven to rotate, and rotary shaft 11 drives disposably
Pallet 14 rotates 180 degree, and sample to be diagnosed is launched to the sample collecting board 21 reprinted in seat 20, and disposable pallet 14 is multiple
Position, the first electric pushrod 18 is run at this time, is driven to reprint seat 20 and pass through escape aperture 4 and is moved upwards, and will be reprinted seat 20 and be reprinted to the
Four electric pushrods, 29 output end corresponding position is simultaneously out of service, and the 4th electric pushrod 29 is run at this time, will be on sample collecting board 21
It is pushed out to 34 lower section of dyeing liquor efferent duct, the 4th electric pushrod 29 and the first electric pushrod 18 reset in succession, pass through dyeing liquor
Efferent duct 34 treats diagnosis sample and carries out dyeing processing, the second electric pushrod 25 starting operation after dyeing, by the follow-up after dyeing
Disconnected sample is elapsed to 35 lower section of observation port, diagnosis is observed to it by electron microscope 36, and obtain diagnostic result；
The processing method of ultrasonic response diagnosis mould are as follows: the operation rotation of the second motor 6 drives rotating wheel 8 to rotate, 8 band of rotating wheel
Dynamic swingle 10, bearing 9, rotary shaft 11, worm screw axle sleeve 12 and disposable pallet 14 rotate 180 degree, when disposable pallet 14
When turning to reprinting 20 top position of seat, the second motor 6 is out of service, and worm screw axle sleeve 12 is engaged with turbine 17 at this time, the first electricity
Machine 16 brings into operation, and worm screw axle sleeve 12 rotates and rotary shaft 11 is driven to rotate, and rotary shaft 11 drives the disposable rotation of pallet 14 180
Degree, sample to be diagnosed are launched to reprinting in seat 20, and disposable pallet 14 resets, and the first electric pushrod 18 is run at this time, are driven
It reprints seat 20 to move upwards across escape aperture 4, seat 20 will be reprinted and reprint to 29 output end corresponding position of the 4th electric pushrod and stop
Only running, third electric pushrod 27 is run at this time, and it will reprint after seat 20 is elapsed to 31 corresponding position of the 6th electric pushrod and reset,
First electric pushrod 18 resets simultaneously, and the 6th electric pushrod 31 is run at this time, will reprint seat 20 and transfers load to ultrasound reactor 33
Top, the sample to be diagnosed reprinted in seat 20 by 33 Duis of ultrasound reactor carries out ultrasound reactor processing, after processing, the
The starting operation of two electric pushrods 25, the passage of seat 20 to be reprinted see it by electron microscope 36 to 35 lower section of observation port
Diagnosis is surveyed, and obtains diagnostic result；
The processing method of infrared processing diagnostic mode are as follows: the operation rotation of the second motor 6 drives rotating wheel 8 to rotate, 8 band of rotating wheel
Dynamic swingle 10, bearing 9, rotary shaft 11, worm screw axle sleeve 12 and disposable pallet 14 rotate 180 degree, when disposable pallet 14
When turning to reprinting 20 top position of seat, the second motor 6 is out of service, and worm screw axle sleeve 12 is engaged with turbine 17 at this time, the first electricity
Machine 16 brings into operation, and worm screw axle sleeve 12 rotates and rotary shaft 11 is driven to rotate, and rotary shaft 11 drives the disposable rotation of pallet 14 180
Degree, sample to be diagnosed are launched to reprinting in seat 20, and disposable pallet 14 resets, and the first electric pushrod 18 is run at this time, are driven
It reprints seat 20 to move upwards across escape aperture 4, seat 20 will be reprinted and reprint to 29 output end corresponding position of the 4th electric pushrod and stop
Only running, third electric pushrod 27 is run at this time, and it will reprint after seat 20 is elapsed to 30 corresponding position of the 5th electric pushrod and reset,
First electric pushrod 18 resets simultaneously, and the 5th electric pushrod 30 is run at this time, will reprint seat 20 and transfers load under red infrared illumination light 32
Side, the sample to be diagnosed reprinted in seat 20 by 32 Duis of red infrared illumination light carries out ultrasound reactor processing, after processing, the second electricity
The dynamic starting of push rod 25 operation, the passage of seat 20 to be reprinted are observed it by electron microscope 36 and examine to 35 lower section of observation port
It is disconnected, and obtain diagnostic result.
Claims (8)
1. a kind of pathological diagnosis device, including bottom plate (1) are mounted on the top plate on bottom plate (1) top by four support rods (5)
(2), the intermediate support plate (3) being arranged between top plate (2) and bottom plate (1), it is characterised in that: opened in the support plate (3)
Equipped with escape aperture (4), the lower part of support plate (3) is provided with rehandling facilities, the top of support plate (3) is provided with transfer dress
It sets, is fixedly installed on bottom plate (1) controller (22), the side of controller (22) is connected with deduster (23), on top plate (2)
It is fixedly installed with the control plate face (37) being connected with controller (22), the side of control plate face (37) is fixedly installed with electronic display
Micro mirror (36).
2. pathological diagnosis device according to claim 1, it is characterised in that: the rehandling facilities includes that setting is leaking out
Reprinting seat (20) below hole (4), the bottom for reprinting seat (20) are movably installed with the first electric pushrod (18), are reprinting seat (20)
Side be fixedly installed with first motor (16), the output end of first motor (16) is fixedly installed with turbine (17), first electricity
The side of machine (16) is fixedly installed with the second motor (6), and the output end of the second motor (6) is fixedly installed with rotating wheel (8), rotation
Wheel (8) is fixedly connected with swingle (10), and swingle (10) is connected by bearing (9) with rotary shaft (11), in rotary shaft
(11) fixing sleeve is equipped with the worm screw axle sleeve (12) matched with turbine (17) on, is equipped with disposably in the end of rotary shaft (11)
Pallet (14), the shifting apparatus are levelling including the displacement being fixedly mounted in the support plate (3) of escape aperture (4) top side
Plate (38) is displaced on looking for flat (38) and is fixedly installed with the second electric pushrod (25), has been provided on support plate (3) and second
The opposite third electric pushrod (27) of the outbound course of electric pushrod (25), in the fixed peace of the output end of the second electric pushrod (25)
Equipped with the first push plate (26), the second push plate (28) are fixedly installed in the output end of third electric pushrod (27), in the first push plate
(26) support plate (3) between the second push plate (28) is fixedly installed with the 4th electric pushrod (29), the 5th electric pushrod (30)
And the 6th electric pushrod (31), the 4th electric pushrod (29), the 5th electric pushrod (30) and the 6th electric pushrod (31)
The outbound course of outbound course and the second electric pushrod (25) and third electric pushrod (27) is mutually perpendicular to, the 4th electric pushrod
(29) corresponding position of the side above escape aperture (4) is set, and the top in the 4th electric pushrod (29) maximum output position is solid
Dingan County is equipped with dyeing liquor efferent duct (34), is provided with red infrared illumination light above the 5th electric pushrod (30) maximum output position
(32), ultrasound reactor (33) are provided with below the 6th electric pushrod (31) maximum output position, electronic are pushed away second
The observation port (35) being connected with electron microscope (36) is provided with above bar (25) maximum output position.
3. pathological diagnosis device according to claim 1, it is characterised in that: four sides of the intermediate support plate (3)
Angle Position is fixedly connected with four support rods (5), and the top plate (2) of intermediate support plate (3), bottom plate (1) and top is rectangular
Shape plate structure is fixedly connected at the top of the bottom and bottom plate (1) of controller (22), and deduster (23) passes through conducting wire and controller
(22) it is connected, is fixedly connected at the top of the bottom and bottom plate (1) of deduster (23), is fixedly mounted in the outside of deduster (23)
There are basket strainer (24), battery main switch (39), staining pattern switch (40), ultrasonication are provided in control plate face (37)
Mode switch (41) and infrared tupe switch (42).
4. pathological diagnosis device according to claim 2, it is characterised in that: the escape aperture (4) is that rectangle is poroid
Structure, reprinting seat (20) is U-shaped Cao Zhuan structure, reprints seat (20) and escape aperture (4) is vertically corresponding, reprint the length of seat (20)
With width no more than the length and width with escape aperture (4), bottom push plate (19) are fixedly installed with reprinting seat (20) bottom,
It is equipped with sample collecting board (21) in the top movable for reprinting seat (20) internal backplane, the bottom surface of bottom push plate (19) and the first electricity
The top surface of dynamic push rod (18) is fixedly connected, and the bottom surface of the first electric pushrod (18) is fixedly connected with the top surface of bottom plate (1), the first electricity
The stroke of dynamic push rod (18) is not less than the distance of bottom push plate (19) bottom surface to escape aperture (4) top surface.
5. pathological diagnosis device according to claim 2, it is characterised in that: the reprinting seat (20) and disposable pallet
(14) equal length is distributed in the two sides of the shaft core position of first motor (16), and disposable pallet (14) is rectangle channel-shaped knot
Structure, the length and width for reprinting seat (20) is not less than the length and width of disposable pallet (14), in disposable pallet (14)
Heart line to the distance between the center line of first motor (16) with reprint center line of seat (20) center line to first motor (16)
The distance between it is equal, turbine (17) and worm screw axle sleeve (12) equal length are distributed in the two sides of the second motor (6) shaft core position,
Horizontal plane locating for horizontal plane locating for turbine (17) top surface and worm screw axle sleeve (12) bottom surface is same plane, rotary shaft (11)
End is connected by movable bolt connector (13) with disposable pallet (14), and first motor (16) passes through first motor bracket
(7) it is fixedly connected with bottom plate (1).
6. pathological diagnosis device according to claim 2, it is characterised in that: the displacement looking for flat (38) is rectangle
Plate structure, is displaced the length of looking for flat (38) and the equal length of support plate (3), and the width of displacement looking for flat (38) is not more than
The outbound course of the width of support plate (3), the second electric pushrod (25) and third electric pushrod (27) is on the contrary, and the second push plate
(28) inside edge position mutually suits with displacement looking for flat (38) inside edge position.
7. pathological diagnosis device according to claim 2, it is characterised in that: first electric pushrod (18), first
Motor (16), the second motor (6), the second electric pushrod (25), third electric pushrod (27), the 4th electric pushrod (29), the 5th
Electric pushrod (30) and the 6th electric pushrod (31), red infrared illumination light (32) and ultrasound reactor (33) pass through conducting wire
It is connected with controller (22), controller (22) is connected by conducting wire with control plate face (37), and first motor (16) passes through the
One motor support bar (15) is connected with support plate (3).
8. a kind of diagnostic method of the pathological diagnosis device as claimed in claim 2, which is characterized in that its diagnostic method
As follows: first under equipment original state, equipment power supply is opened in control plate face (37), at this time disposable pallet (14) initial position
Positioned at equipment entirety outer fix, the sample to be diagnosed being collected is thrown in disposable pallet (14), and passes through control panel
Face (37) running equipment, equipment is there are three types of diagnostic mode, respectively Staining for Diagnosis mode, ultrasonic response diagnostic mode and infrared
Diagnostic mode is handled, selects one of diagnostic mode to carry out processing operation by control plate face (37)；
The processing method of Staining for Diagnosis mode are as follows: the second motor (6) operation rotation drives rotating wheel (8) rotation, rotating wheel (8)
Swingle (10), bearing (9), rotary shaft (11), worm screw axle sleeve (12) and disposable pallet (14) is driven to rotate 180 degree, when
When disposable pallet (14) turns to reprinting seat (20) top position, the second motor (6) is out of service, at this time worm screw axle sleeve (12)
It is engaged with turbine (17), first motor (16) brings into operation, and worm screw axle sleeve (12) rotates and rotary shaft (11) is driven to rotate, rotation
Axis (11) drives disposable pallet (14) to rotate 180 degree, and sample to be diagnosed is launched into reprinting seat (20), disposable pallet
(14) it resets, the first electric pushrod (18) is run at this time, is driven reprinting seat (20) to pass through escape aperture (4) and is moved upwards, will reprint
Seat (20) is reprinted to the 4th electric pushrod (29) output end corresponding position and out of service, and the 4th electric pushrod (29) is transported at this time
Sample to be diagnosed is pushed out to below dyeing liquor efferent duct (34) from reprinting in seat (20) by row, the 4th electric pushrod (29) and
First electric pushrod (18) resets in succession, treats diagnosis sample by dyeing liquor efferent duct (34) and carries out dyeing processing, after dyeing
Second electric pushrod (25) starting operation, the sample to be diagnosed after dyeing is elapsed to observation port (35), electronic display is passed through
Micro mirror (36) is observed diagnosis to it, and obtains diagnostic result；
The processing method of ultrasonic response diagnosis mould are as follows: the second motor (6) operation rotation drives rotating wheel (8) rotation, rotating wheel
(8) swingle (10), bearing (9), rotary shaft (11), worm screw axle sleeve (12) and disposable pallet (14) is driven to rotate 180 degree,
When disposable pallet (14), which turns to, reprints seat (20) top position, the second motor (6) is out of service, at this time worm screw axle sleeve
(12) it being engaged with turbine (17), first motor (16) brings into operation, and worm screw axle sleeve (12) rotates and rotary shaft (11) is driven to rotate,
Rotary shaft (11) drives disposable pallet (14) to rotate 180 degree, and sample to be diagnosed is launched to reprinting in seat (20), disposably holds in the palm
Disk (14) resets, and the first electric pushrod (18) is run at this time, drives reprinting seat (20) to pass through escape aperture (4) and moves upwards, will turn
It carries seat (20) to reprint to the 4th electric pushrod (29) output end corresponding position and out of service, third electric pushrod (27) is transported at this time
Row will be reprinted after seat (20) are elapsed to the 6th electric pushrod (31) corresponding position and be resetted, and the first electric pushrod (18) is multiple simultaneously
Position, the 6th electric pushrod (31) is run at this time, will be reprinted seat (20) and is transferred load to above ultrasound reactor (33), passes through ultrasonic wave
Reactor (33) carries out ultrasound reactor processing, after processing, the second electric pushrod to the sample to be diagnosed reprinted in seat (20)
(25) starting operation, seat (20) passage to be reprinted are observed it by electron microscope (36) to observation port (35) lower section
Diagnosis, and obtain diagnostic result；
The processing method of infrared processing diagnostic mode are as follows: the second motor (6) operation rotation drives rotating wheel (8) rotation, rotating wheel
(8) swingle (10), bearing (9), rotary shaft (11), worm screw axle sleeve (12) and disposable pallet (14) is driven to rotate 180 degree,
When disposable pallet (14), which turns to, reprints seat (20) top position, the second motor (6) is out of service, at this time worm screw axle sleeve
(12) it being engaged with turbine (17), first motor (16) brings into operation, and worm screw axle sleeve (12) rotates and rotary shaft (11) is driven to rotate,
Rotary shaft (11) drives disposable pallet (14) to rotate 180 degree, and sample to be diagnosed is launched to reprinting in seat (20), disposably holds in the palm
Disk (14) resets, and the first electric pushrod (18) is run at this time, drives reprinting seat (20) to pass through escape aperture (4) and moves upwards, will turn
It carries seat (20) to reprint to the 4th electric pushrod (29) output end corresponding position and out of service, third electric pushrod (27) is transported at this time
Row will be reprinted after seat (20) are elapsed to the 5th electric pushrod (30) corresponding position and be resetted, and the first electric pushrod (18) is multiple simultaneously
Position, the 5th electric pushrod (30) is run at this time, will be reprinted seat (20) and is transferred load to below red infrared illumination light (32), passes through infrared radiation
Lamp (32) carries out ultrasound reactor processing, after processing, the second electric pushrod (25) to the sample to be diagnosed reprinted in seat (20)
Starting operation, seat (20) passage to be reprinted to observation port (35) lower section, is observed diagnosis to it by electron microscope (36),
And obtain diagnostic result.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811211987.6A CN109163954B (en) | 2018-10-18 | 2018-10-18 | Pathological diagnosis device and method thereof |
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811211987.6A CN109163954B (en) | 2018-10-18 | 2018-10-18 | Pathological diagnosis device and method thereof |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112960250A (en) * | 2021-04-12 | 2021-06-15 | 许昌学院 | Intelligent medical classified storage and inspection box and using method thereof |
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