CN109142697B - 一种生物样品定量收集器及其应用 - Google Patents
一种生物样品定量收集器及其应用 Download PDFInfo
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- CN109142697B CN109142697B CN201810374712.8A CN201810374712A CN109142697B CN 109142697 B CN109142697 B CN 109142697B CN 201810374712 A CN201810374712 A CN 201810374712A CN 109142697 B CN109142697 B CN 109142697B
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
- G16B25/10—Gene or protein expression profiling; Expression-ratio estimation or normalisation
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150015—Source of blood
- A61B5/150022—Source of blood for capillary blood or interstitial fluid
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/15—Devices for taking samples of blood
- A61B5/150007—Details
- A61B5/150358—Strips for collecting blood, e.g. absorbent
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5023—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures with a sample being transported to, and subsequently stored in an absorbent for analysis
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5025—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures for parallel transport of multiple samples
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/483—Physical analysis of biological material
- G01N33/487—Physical analysis of biological material of liquid biological material
- G01N33/49—Blood
- G01N33/492—Determining multiple analytes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
- G01N33/54366—Apparatus specially adapted for solid-phase testing
- G01N33/54386—Analytical elements
- G01N33/54387—Immunochromatographic test strips
- G01N33/54388—Immunochromatographic test strips based on lateral flow
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6803—General methods of protein analysis not limited to specific proteins or families of proteins
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6893—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids related to diseases not provided for elsewhere
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B20/00—ICT specially adapted for functional genomics or proteomics, e.g. genotype-phenotype associations
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- G—PHYSICS
- G16—INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR SPECIFIC APPLICATION FIELDS
- G16B—BIOINFORMATICS, i.e. INFORMATION AND COMMUNICATION TECHNOLOGY [ICT] SPECIALLY ADAPTED FOR GENETIC OR PROTEIN-RELATED DATA PROCESSING IN COMPUTATIONAL MOLECULAR BIOLOGY
- G16B25/00—ICT specially adapted for hybridisation; ICT specially adapted for gene or protein expression
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/18—Transport of container or devices
- B01L2200/185—Long distance transport, e.g. mailing
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0832—Geometry, shape and general structure cylindrical, tube shaped
- B01L2300/0845—Filaments, strings, fibres, i.e. not hollow
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/12—Specific details about materials
- B01L2300/126—Paper
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0403—Moving fluids with specific forces or mechanical means specific forces
- B01L2400/0406—Moving fluids with specific forces or mechanical means specific forces capillary forces
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N2001/002—Devices for supplying or distributing samples to an analysing apparatus
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N1/00—Sampling; Preparing specimens for investigation
- G01N1/02—Devices for withdrawing samples
- G01N1/10—Devices for withdrawing samples in the liquid or fluent state
- G01N1/14—Suction devices, e.g. pumps; Ejector devices
- G01N2001/1472—Devices not actuated by pressure difference
- G01N2001/149—Capillaries; Sponges
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00108—Test strips, e.g. paper
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- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Physics & Mathematics (AREA)
- Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
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- Immunology (AREA)
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- Pathology (AREA)
- Urology & Nephrology (AREA)
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- Bioinformatics & Cheminformatics (AREA)
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- Genetics & Genomics (AREA)
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- Bioinformatics & Computational Biology (AREA)
- Medicinal Chemistry (AREA)
- Food Science & Technology (AREA)
- Spectroscopy & Molecular Physics (AREA)
- Evolutionary Biology (AREA)
- Theoretical Computer Science (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Clinical Laboratory Science (AREA)
- Cell Biology (AREA)
- Microbiology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Animal Behavior & Ethology (AREA)
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- Veterinary Medicine (AREA)
- Ecology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
CA125-serum | CA125-DBS |
40 | 7 |
78 | 32 |
23 | 17 |
128 | 97 |
74 | 49 |
109 | 77 |
205 | 255 |
532 | 463 |
CA72-4-serum | CA72-4-DBS |
1070 | 943 |
930 | 805 |
837 | 701 |
882 | 726 |
843 | 711 |
797 | 612 |
812 | 688 |
901 | 794 |
CEA-serum | CEA-DBS |
119 | 234 |
693 | 607 |
274 | 356 |
282 | 317 |
652 | 567 |
221 | 262 |
494 | 395 |
186 | 175 |
Pepsinogen 2-serum | Pepsinogen 2-DBS |
3182 | 1960 |
1058 | 493 |
1185 | 899 |
5706 | 3070 |
1026 | 629 |
1444 | 1018 |
1332 | 1093 |
743 | 470 |
Claims (8)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
USUS15/581,440 | 2017-04-28 | ||
US15/581,440 US10210307B2 (en) | 2017-04-28 | 2017-04-28 | Method of determining protein expression |
Publications (2)
Publication Number | Publication Date |
---|---|
CN109142697A CN109142697A (zh) | 2019-01-04 |
CN109142697B true CN109142697B (zh) | 2020-08-07 |
Family
ID=63916188
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810374712.8A Active CN109142697B (zh) | 2017-04-28 | 2018-04-24 | 一种生物样品定量收集器及其应用 |
CN201820597181.4U Active CN208953547U (zh) | 2017-04-28 | 2018-04-24 | 生物流体样品收集装置及其试剂盒 |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201820597181.4U Active CN208953547U (zh) | 2017-04-28 | 2018-04-24 | 生物流体样品收集装置及其试剂盒 |
Country Status (2)
Country | Link |
---|---|
US (2) | US10210307B2 (zh) |
CN (2) | CN109142697B (zh) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN105769909A (zh) * | 2016-05-13 | 2016-07-20 | 云南舜喜再生医学工程有限公司 | 一种直接获得富含细胞因子血清的采血器及方法 |
EP3944814B1 (de) * | 2020-07-30 | 2022-12-07 | Protzek Biotec GmbH | Vorrichtung zur entnahme einer flüssigkeitsprobe |
WO2023219095A1 (ja) * | 2022-05-11 | 2023-11-16 | Craif株式会社 | 対象液体に含まれる対象物質を分離する方法 |
GB2619127A (en) * | 2022-05-23 | 2023-11-29 | Zhejiang Orient Gene Biotech Co Ltd | Test device for analyte in a fluid sample |
KR102643059B1 (ko) * | 2023-03-16 | 2024-03-06 | 고려대학교 산학협력단 | 공기 중 이소티아졸리논계 물질을 정량 분석하기 위한 수동채취기 및 이를 이용한 공기 중 이소티아졸리논계 물질의 정량 분석방법 |
Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4933092A (en) * | 1989-04-07 | 1990-06-12 | Abbott Laboratories | Methods and devices for the separation of plasma or serum from whole blood |
CN1980738A (zh) * | 2004-04-09 | 2007-06-13 | 科研智囊团有限公司 | 用于收集、储存和运输生物样本的设备和方法 |
CN102182116A (zh) * | 2011-03-14 | 2011-09-14 | 东莞南方医大代谢医学研发有限公司 | 一种收集生物样本的滤纸制备及运用方法 |
CN204606598U (zh) * | 2015-03-13 | 2015-09-02 | 柳州市妇幼保健院 | 新生儿筛查血片存储册 |
CN105771308A (zh) * | 2016-04-28 | 2016-07-20 | 中国药科大学 | 一种高效萃取动物源性食品中磺胺类药物残留的方法 |
CN205602331U (zh) * | 2016-05-13 | 2016-09-28 | 新疆维吾尔自治区人民医院 | 一种适用于新生儿筛查血片的存储箱 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE8711962U1 (de) * | 1987-09-01 | 1987-11-05 | Hermann, Brigitte, Dr.med., 8700 Würzburg | Vorrichtung zur Aufnahme einer Mehrzahl von Trägerelementen |
DE19700626A1 (de) * | 1997-01-10 | 1998-07-16 | Europ Lab Molekularbiolog | Probenzuführung |
WO2002089723A2 (en) * | 2001-05-08 | 2002-11-14 | Biosafe Medical Technologies, Inc. | Body fluid collection device |
BR112013022735A2 (pt) * | 2011-03-09 | 2016-12-06 | 3M Innovative Properties Co | aparelho para processamento de uma amostra, aparelho para processamento de uma pluralidade de amostras, método para detectar a presença ou ausência de um analito em uma amostra e método para detectar a presença ou ausência de um analito em uma pluralidade de amostras |
-
2017
- 2017-04-28 US US15/581,440 patent/US10210307B2/en active Active
-
2018
- 2018-04-24 CN CN201810374712.8A patent/CN109142697B/zh active Active
- 2018-04-24 CN CN201820597181.4U patent/CN208953547U/zh active Active
- 2018-10-31 US US16/175,916 patent/US20190065673A1/en not_active Abandoned
Patent Citations (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4933092A (en) * | 1989-04-07 | 1990-06-12 | Abbott Laboratories | Methods and devices for the separation of plasma or serum from whole blood |
CN1980738A (zh) * | 2004-04-09 | 2007-06-13 | 科研智囊团有限公司 | 用于收集、储存和运输生物样本的设备和方法 |
CN102182116A (zh) * | 2011-03-14 | 2011-09-14 | 东莞南方医大代谢医学研发有限公司 | 一种收集生物样本的滤纸制备及运用方法 |
CN204606598U (zh) * | 2015-03-13 | 2015-09-02 | 柳州市妇幼保健院 | 新生儿筛查血片存储册 |
CN105771308A (zh) * | 2016-04-28 | 2016-07-20 | 中国药科大学 | 一种高效萃取动物源性食品中磺胺类药物残留的方法 |
CN205602331U (zh) * | 2016-05-13 | 2016-09-28 | 新疆维吾尔自治区人民医院 | 一种适用于新生儿筛查血片的存储箱 |
Also Published As
Publication number | Publication date |
---|---|
US20180314792A1 (en) | 2018-11-01 |
CN208953547U (zh) | 2019-06-07 |
CN109142697A (zh) | 2019-01-04 |
US20190065673A1 (en) | 2019-02-28 |
US10210307B2 (en) | 2019-02-19 |
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