CN109125892A - A kind of distal end blocking type stereo spiral pigtail structure pulmonary thrombosis suction catheter - Google Patents

A kind of distal end blocking type stereo spiral pigtail structure pulmonary thrombosis suction catheter Download PDF

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Publication number
CN109125892A
CN109125892A CN201810924683.8A CN201810924683A CN109125892A CN 109125892 A CN109125892 A CN 109125892A CN 201810924683 A CN201810924683 A CN 201810924683A CN 109125892 A CN109125892 A CN 109125892A
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CN
China
Prior art keywords
pigtail
conduit
catheter
seal wire
vertical connections
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201810924683.8A
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Chinese (zh)
Inventor
张海军
王智勇
周超
冯相蓺
宋彩霞
张军伟
崔晓珊
赵彦伟
徐凯丽
侯文博
李宁
鲁手涛
段翠海
尹玉霞
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Individual
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Individual
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Priority to CN201810924683.8A priority Critical patent/CN109125892A/en
Publication of CN109125892A publication Critical patent/CN109125892A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0021Catheters; Hollow probes characterised by the form of the tubing
    • A61M25/0023Catheters; Hollow probes characterised by the form of the tubing by the form of the lumen, e.g. cross-section, variable diameter
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0057Catheters delivering medicament other than through a conventional lumen, e.g. porous walls or hydrogel coatings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M2025/0063Catheters; Hollow probes characterised by structural features having means, e.g. stylets, mandrils, rods or wires to reinforce or adjust temporarily the stiffness, column strength or pushability of catheters which are already inserted into the human body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/10Trunk
    • A61M2210/1025Respiratory system
    • A61M2210/1039Lungs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M2210/00Anatomical parts of the body
    • A61M2210/12Blood circulatory system
    • A61M2210/127Aorta

Abstract

The invention discloses a kind of pigtail structure pulmonary thrombosis suction catheter with thrombolysis, Biochemical analyzer function, risk that can be free in distal end barrier thrombus fragmentation belong to medical instruments field.Main structure includes catheter main body 1 and end of conduit 2, end of conduit 2 includes vertical connections 3 and stereo spiral pigtail 4, catheter main body part is three lumens, contain guidewire lumen 10, functional chamber 5 and suction chamber 6, there are three the drugs with unidirectional opening valve to exchange mouth 7 on the outside of functional chamber, developing ring 8, Y type connector 9.The present invention, which aspirates header structure, has shape memory function, can form the helical structure of pellet type in thrombus distal end, the free risk of bolt block be effectively reduced, while porous surface improves pumping efficiency.

Description

A kind of distal end blocking type stereo spiral pigtail structure pulmonary thrombosis suction catheter
Technical field
The present invention relates to medical instruments fields, dynamic more particularly to a kind of distal end blocking type stereo spiral pigtail structure lung The structural principle of arteries and veins thrombus suction catheter.
Background technique
Acute pulmonary embolism (acute pulmonary thromboembolism, APTE) is that the U.S. generally acknowledges One of three big lethal cardiovascular diseases, for the high-risk APTE patient of pulmonary artery proximal segment thromboembolism, when there is thrombolysis contraindication Or when thromboembolism treatment and invalid positive medical treatment, huge thrombus or row balloon in conduit size degradation and suction pulmonary artery can be used Plasty, while Low dose Thrombolysis agent thrombolysis is administered locally to, it can obviously improve pulmonary hemodynamics index.In acute/big Block pulmonary embolism is clinical much danger diseases, and untreated person's death rate is more than 70 %, early diagnosis, timely intravenous thrombolysis, Anticoagulant equal treatments can reduce the death rate;In acute/Massive pulmonary embolism is using a variety of intervention materials, different operating methods is passed through One of the idicatio of skin pulmonary artery intervenien therapy.Such as through the broken bolt of vein pulmonary artery inner catheter, with dedicated thrombus remove device, such as Hydrolyser, ATD thrombus, which melt device, PTD thrombus remove device etc., absorbs urokinase, rtPA in thrombus and application pulmonary artery The technologies such as contact thrombolysis.The country still lacks this respect system research report.
The thrombus that the embolus overwhelming majority of pulmonary embolism is formed in pelvic veins or deep veins of lower limb, after thrombus breaks loose Free embolus by blood circulation, the embolism of pulmonary artery system is caused via atrium dextrum, right ventricle.Embolism type is main Depending on entering Pulmonary Vascular thrombus block size and blocking ranges, " massive type " and " secondary massive type " pulmonary embolism may occur in which PTE's The indirect sign of echocardiogram, and the pulmonary embolism of small-to-midsize and the embolus far from pulmonary artery section, from chest ultrasonic cardiography The change of specificity is difficult to find on figure.Clinically, " massive type " embolus can block about 80% lobe of the lung blood flow, " secondary huge Block type " embolus can then block 50%~76% lobe of the lung blood flow.
The key link of APTE treatment is that contacting pulmonary thrombosis as early as possible blocks, and realizes that pulmonary circulation is led to again.According to thunder et al. Research report, center pulmonary artery size is respectively as follows: main pulmonary artery (24.5 ± 3.4) mm;Right pulmonary artery (16.9 ± 2.6) mm; Left pulmonary artery (16.3 ± 1.8) mm;Superior lobe of right lung artery (6.1 ± 1.3) mm;Right lung interlobar arteries (12.0 ± 1.6) mm;It is left Lung interlobar arteries (11.3 ± 1.4) mm.The treatments such as conventional thrombolytic-anticoagulant it is invalid, there are when taboo or the dangerous state of an illness, percutaneously The broken bolt of conduit inhales bolt because having many advantages, such as to improve rapidly haemodynamics and hypoxemia, wound are small and feasibility is strong is made For the remedy measures of recommendation.Both at home and abroad be no lack of using cardiovascular intervention and inhale bolt conduit (Greenfield except bolt conduit, Percutaneously using telescope coaxial system inhale bolt art, big lumen 8FPTCA guiding catheter) carry out pulmonary artery suction take bolt, and blood Bolt ablation catheter (rotation recycling device, as Amplaz thrombus melt device), high pressure water flow recycling device (Angiojet, Hydrolyse and Oasis remove bolt conduit) etc. be used for critical Pulmonary Embolism Patients rescue, obtain preferable effect.These devices are big It is more not to aim at pulmonary embolism and design and expensive;Also have no that the dedicated pulmonary artery of domestic independent research removes bolt The research of device is reported.In emergency treatment, in pulmonary embolism interventional procedure, local thrombolysis, mechanical broken bolt, thrombus are taken out The free of thrombus bolt block may be caused by being drawn through journey all, cause the blocking of small distal blood vessels, risk is higher.
Pigtail catheter, end are in coiled structure, are similar to pigtail, using extremely wide in surgical operation, such as pig Tail pipe drainage treatment spontaneous pneumothorax, with rotatable pigtail catheter mechanical disintegration acute massive pulmonary embolism etc..It is with bracket It can be designed by structure and the free wind of thrombus bolt block is effectively reduced in pulmonary thrombosis aspiration procedure with interior drainage Danger and raising pumping efficiency and safety.
United States Patent (USP) 9332914 discloses left ventricle and active of a kind of annula pigtail measurement across aorta petal Method of the differential pressure to diagnose aortic stenosis between arteries and veins is combined the thin-wallconduit technology for exocoel, and is compiled using strong Diagnostic techniques is knitted for central chamber to adapt to high-pressure injection.Conduit includes manifold bodies to provide the connection with each two-chamber.Together The distal end tapers of axis Double cavity pig tail conduit are perforated at more soft part by spiral side opening to provide more not in left ventricle The pressure reading of distortion.
United States Patent (USP) 8568326 provides a kind of IVUS pigtail catheter.IVUS pigtail catheter includes to be used for intravascular ultrasound The transducer array of imaging and pigtail end part for angiographic imaging.IVUS pigtail catheter can carry out simultaneously IVUS at Picture and angiographic imaging, without replacing conduit.IVUS pigtail catheter makes surgical procedure carry out ground faster, more acurrate, simpler It is single.Patent additionally provides the method using IVUS pigtail catheter.
United States Patent (USP) 5037403 discloses a kind of pigtail catheter with angled hole, the flexible pipe including limiting inner cavity Multiple side openings therein are flowed through with for liquid, each freedom of side opening extends through tube wall to external tubular surface from lumen It limits, at least some of described tubular surface limits second longitudinal direction axis, and the second longitudinal direction axis forms about 30 ° and arrives 60 ° of forward angle.Intersect with the longitudinal axis of the conduit of the neighbouring tubular surface, the distal end is that integral diameter is about The pigtail form of tubes of 10mm to 14mm, the side opening limit open pore, hence improve X adjacent to the pigtail, the distal end The flow behavior of ray-contrast media, to obtain the visualization of better internal's X-ray.
Chinese patent CN104436409 A discloses a kind of anti-discounting pigtail catheter, including catheter body, the conduit Ontology includes catheter tube and is threaded through the intracorporal seal wire of catheter tube, and the seal wire includes stamen silk and coiling set, described to lead By there is the plastic material of shape memory to be made, the coiling set is formed pipe tube body by the spiral wrapping wire of stacked arrangement, described Stamen silk is made of shape-memory material, so that stamen silk is still able to maintain preferable reset condition after multiple bending, and passes through spiral The coiling set of shape prevents the generation of malpractice so that remain to tend to remain in conduit situation on sale.
Chinese patent CN102847222 A discloses a kind of Degradable hydrophilic pigtail conduit, including tube body, affiliated to lead Guan Weishuan J-type conduit or list J conduit, the one or both ends of the tube body are set as pigtail shape, the tube body material of affiliated conduit For hydrophilic degradable material, which is made of biological absorbable aliphatic poly ester material, can voluntarily decompose, can also be by micro- life The effects of object, enzyme, is gradually decomposed into small molecule, then excretes via metabolism.Successfully second operation is avoided to extract, subtracted Light patient's pain, increases operation safety.
The present invention devises a kind of pulmonary thrombosis suction catheter, with the pigtail patent announced both at home and abroad that retrieves Structure and function feature is different.
Summary of the invention
In order to overcome the shortage of prior art, the present invention provides a kind of distal end blocking type stereo spiral pigtail structure pulmonary artery blood Bolt suction catheter.
The invention discloses a kind of pigtail structure pulmonary thrombosis suction catheter with thrombolysis, Biochemical analyzer function, Medical instruments field can be belonged in the risk that distal end barrier thrombus dissociates.Main structure includes catheter main body 1 and end of conduit 2, end of conduit 2 includes vertical connections 3 and stereo spiral pigtail 4, and catheter main body part is three lumens, contains guidewire lumen 10, functional chamber 5 and suction chamber 6, there are three the drug exchange mouth 7 with unidirectional opening valve, developing ring 8, Y types in functional chamber outside Connector 9.Seal wire can bend to the funnel-shaped structure perpendicular to catheter main body, 4 surface side of stereo spiral pipe and side when withdrawing from Wall has suction hole.Thrombolytic Drugs, thrombus, while helicoidal structure can be got by fast exchange mouth from functional chamber can be with Extract thrombus out.
1. the thrombus suction catheter structure includes: catheter main body 1 and end of conduit 2, end of conduit 2 includes vertical connection Part 3 and stereo spiral pipe 4, catheter main body part is double lumen tube, is had containing functional chamber 5 and suction chamber 6, on the outside of functional chamber one quick Exchange mouth (RX mouthfuls) 7, developing ring 8, Y type connector 9.
2.Y type connector 9 can be plastic material, by technological formings such as injection moldings, by bonding or being molded in suction Catheter proximal end connection.Wherein two openings of Y type connector 7 are connected in proximal end with two chambers of suction catheter respectively respectively.Y type The external tapping of connector may be designed as the female Luer with 6% taper or lock port or the size of other requirements.
3. catheter main body 1 is double lumen tube, contain functional chamber 5 and suction chamber 6.Functional chamber 5 can transport Thrombolytic Drugs, and medical fluid is in side Drug exchange mouth release, thrombus on wall.
4. it is 1 ~ 3cm that drug, which exchanges oral lobe film length,.
5. catheter main body material is the high molecular materials such as pebax, PTFE, silica gel, antibacterial super slippery coating is coated with outside catheter main body.
6. developing ring is the good inert materials of X-rays developability such as platinumiridio, platinum evanohm.
7. the vertical connections 3 and stereo spiral pipe pigtail 4 of end of conduit are inserted into stage delivery conduit process in seal wire In, end of conduit is straight configuration.After withdrawing from seal wire, end can revert to rolled state, be formed vertical with catheter main body Spiral structure.
8. pigtail 4 is funnel-shaped, inner surface has porous, bolt block can be prevented free, blocked small distal blood vessels with aspirate thrombi.
9. thrombolytic drug includes but is not limited to, streptokinase, urokinase, people recombinate t-PA(rt-PA, Alteplase), it is auspicious for general Enzyme (r-PA), the drugs such as lanoplase (n-PA) and Tenecteplase (TNK-tPA).
10. conduit cavity has certain intensity, prevent from being crushed when working in negative pressure.
11. end of conduit material is the materials such as silica gel, plastic cement or marmem.
12. application method of the invention includes the following steps: 1. conduit is delivered to thrombus distal end by seal wire by step;Step Suddenly seal wire is 2. withdrawn into end of conduit, end of conduit automatic curled forms funnel-shaped structure, forms barrier in thrombus distal end;Step Suddenly Thrombolytic Drugs 3. are squeezed into from functional chamber;Step 4. catheter proximal end to negative pressure, aspirate thrombi.
13. operation needs two people or more that can complete.
14. the connection method of end of conduit and catheter main body includes but is not limited to the methods of laser welding, lamination pyrocondensation.
15. suction catheter diameter is in 3mm ~ 20mm.
Compared with prior art, gain effect of the invention is:
1. improving thrombus efficiency with spiral pigtail structure, the free risk of bolt block is reduced;
2. end of conduit structure enhances fixed function, keep aspiration procedure more acurrate;
3. the funneling suction bulk embolism of distal end baffle type, surface has porous, and more efficient, safety is stronger.
Specific embodiment
The following are preferable implementations of the invention, and certainly, the present invention can also use the form different from the embodiment, Those skilled in the art's made equivalent transformation or corresponding modification on the premise of without prejudice to spirit of the invention, all In belonging to the scope of protection of the present invention.
Embodiment 1:
With reference to Fig. 1 ~ Fig. 2.As shown in Figure 1, a kind of pulmonary thrombosis suction catheter, catheter main body part 1 is 1300 ~ 1600mm's Three lumens, functional chamber 5 have one-way valve at three to be open at distance suction 20 ~ 35mm of platform plane, are used to at thrombus convey Thrombolytic drug, valve prevent medical fluid and thrombus from flowing backwards blocking function chamber.Guidewire lumen 10 and suction chamber 6 are connected with end of conduit 2, lead 1 internal diameter of pipe main body is 4 ~ 6mm.End of conduit 2 includes vertical connections 3 and porous pigtail structure 4.Vertical connections 3 are shape Shape memory alloys weave, and alloy outer is pebax material.Length is 10 ~ 12mm when connector stretches, when no seal wire passes through When, rectangular connection status.Pigtail structural material is medical silica-gel, forms by hot extrusion, keeps spiral under natural conditions The curling pigtail structure of shape, maximum gauge are 12 ~ 20mm.Pigtail structure 4 and catheter main body 1 and are hung down by lamination pyrocondensation Straight connector 3 is connected.Y type connector is finally installed.
Detailed description of the invention:
Fig. 1 pulmonary thrombosis suction catheter schematic diagram
Fig. 2 pulmonary thrombosis suction catheter uses schematic diagram.

Claims (7)

1. a kind of pigtail structure pulmonary thrombosis suction catheter with thrombolysis, Biochemical analyzer function, including catheter main body 1, End of conduit 2, vertical connections 3, pigtail 4, guidewire lumen 10, functional chamber 5, suction chamber 6, drug exchange mouth 7, developing ring 8 with And Y type connector 9.
2. pulmonary thrombosis suction catheter as described in claim 1, end of conduit pigtail 4 keeps stretching when being inserted into seal wire Straight state, when seal wire is withdrawn, can automatic curled funnel spiral pigtail structure.
3. drug as described in claim 1 exchanges mouth 7, drug can be prevented to conduit outer openings with one-way valve Or the reflux of bolt block, avoid blocking functional chamber 5.
4. stereo spiral pigtail structure as described in claim 1, material includes but is not limited to medical silicone tube, metal knitted Pipe and high-molecule metal multiple tube.
5. pigtail structure as claimed in claim 4, moulding process includes but is not limited to the modes such as hot extrusion, braiding.
6. vertical connections 3 as described in claim 1, it is characterised in that when seal wire penetrates, shape is stretched in vertical connections holding State, after seal wire is withdrawn from, vertical connections can restore rectangular shape, and size is no more than 3 ~ 5cm when stretching.
7. vertical connections 3 as described in claim 1 and pigtail structure 4, it is characterised in that when seal wire penetrates, tube body is protected Hold straight configuration;After seal wire is withdrawn from, vertical connections 3 and pigtail structure 4 form the stereo spiral perpendicular to catheter main body Shape suction structure.
CN201810924683.8A 2018-08-14 2018-08-14 A kind of distal end blocking type stereo spiral pigtail structure pulmonary thrombosis suction catheter Pending CN109125892A (en)

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CN201810924683.8A CN109125892A (en) 2018-08-14 2018-08-14 A kind of distal end blocking type stereo spiral pigtail structure pulmonary thrombosis suction catheter

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Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6511492B1 (en) * 1998-05-01 2003-01-28 Microvention, Inc. Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders
US20070060908A1 (en) * 2005-08-18 2007-03-15 Webster Mark W L Thrombectomy catheter
CN201058169Y (en) * 2007-05-24 2008-05-14 席刚明 Coaxial saccule thrombolysis trachea
JP2014200529A (en) * 2013-04-05 2014-10-27 ユニチカ株式会社 Drain catheter
CN108283758A (en) * 2018-01-24 2018-07-17 张海军 It is a kind of that there is broken, thrombolysis Biochemical analyzer function medicine eluting balloon catheter

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6511492B1 (en) * 1998-05-01 2003-01-28 Microvention, Inc. Embolectomy catheters and methods for treating stroke and other small vessel thromboembolic disorders
US20070060908A1 (en) * 2005-08-18 2007-03-15 Webster Mark W L Thrombectomy catheter
CN201058169Y (en) * 2007-05-24 2008-05-14 席刚明 Coaxial saccule thrombolysis trachea
JP2014200529A (en) * 2013-04-05 2014-10-27 ユニチカ株式会社 Drain catheter
CN108283758A (en) * 2018-01-24 2018-07-17 张海军 It is a kind of that there is broken, thrombolysis Biochemical analyzer function medicine eluting balloon catheter

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