CN106924864A - A kind of anti-reflux ureter bracket of super-hydrophobic oleophobic - Google Patents

A kind of anti-reflux ureter bracket of super-hydrophobic oleophobic Download PDF

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Publication number
CN106924864A
CN106924864A CN201710169126.5A CN201710169126A CN106924864A CN 106924864 A CN106924864 A CN 106924864A CN 201710169126 A CN201710169126 A CN 201710169126A CN 106924864 A CN106924864 A CN 106924864A
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CN
China
Prior art keywords
ureter
end part
ureter bracket
hydrophobic oleophobic
bladder
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201710169126.5A
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Chinese (zh)
Inventor
宛新建
张伟星
杨莹
黎金臻
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Shanghai First Peoples Hospital
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Shanghai First Peoples Hospital
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Application filed by Shanghai First Peoples Hospital filed Critical Shanghai First Peoples Hospital
Priority to CN201710169126.5A priority Critical patent/CN106924864A/en
Publication of CN106924864A publication Critical patent/CN106924864A/en
Pending legal-status Critical Current

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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0017Catheters; Hollow probes specially adapted for long-term hygiene care, e.g. urethral or indwelling catheters to prevent infections
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M27/00Drainage appliance for wounds or the like, i.e. wound drains, implanted drains
    • A61M27/002Implant devices for drainage of body fluids from one part of the body to another
    • A61M27/008Implant devices for drainage of body fluids from one part of the body to another pre-shaped, for use in the urethral or ureteral tract
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0067Catheters; Hollow probes characterised by the distal end, e.g. tips
    • A61M25/0068Static characteristics of the catheter tip, e.g. shape, atraumatic tip, curved tip or tip structure
    • A61M25/007Side holes, e.g. their profiles or arrangements; Provisions to keep side holes unblocked
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/01Introducing, guiding, advancing, emplacing or holding catheters
    • A61M25/02Holding devices, e.g. on the body
    • A61M25/04Holding devices, e.g. on the body in the body, e.g. expansible
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61MDEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
    • A61M25/00Catheters; Hollow probes
    • A61M25/0043Catheters; Hollow probes characterised by structural features
    • A61M25/0045Catheters; Hollow probes characterised by structural features multi-layered, e.g. coated
    • A61M2025/0046Coatings for improving slidability

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Biomedical Technology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biophysics (AREA)
  • Pulmonology (AREA)
  • Urology & Nephrology (AREA)
  • Otolaryngology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Epidemiology (AREA)
  • External Artificial Organs (AREA)
  • Prostheses (AREA)

Abstract

The present invention relates to a kind of anti-reflux ureter bracket of super-hydrophobic oleophobic, described ureter bracket is tubular body, and a diameter of 1 3mm is sequentially provided with kidney end part, partial ureter and bladder end part;Described kidney end part is in curly, and distal end end face is opening;Described bladder end part is also in curly, and proximal face is closing;Described kidney end part and the inside of partial ureter are all hollow, and outer wall is provided with some staggered conduction holes;The conduction hole of most proximal end is 3 10cm with the distance of bladder end part;The inner surface of described ureter bracket and outer surface are equipped with hydrophobic oleophobic layer, and described hydrophobic oleophobic thickness degree is 50 200nm.Be isolated for body fluid, urine and ureter bracket by the hydrophobic oleophobic layer on ureter bracket surface of the invention, and then prevents the generation of blocking, adhesion, inflammation and courses of infection, and the anti-reflux effect of the ureter bracket is protruded, and possesses good drainage patency.

Description

A kind of anti-reflux ureter bracket of super-hydrophobic oleophobic
Technical field
The present invention relates to technical field of medical instruments, specifically, it is related to a kind of anti-reflux ureter of super-hydrophobic oleophobic Support.
Background technology
Ureter bracket is instrument the most frequently used during various benign and malignant disease in the urological systems are treated, and its effect includes interior Support and interior drainage, can effectively release upper urinary stone, the temporary upper urinary that ureter oedema is caused, and prevention of postoperative is defeated Narrow and leakage of urine the generation of urinary catheter, recovers beneficial to Ipsilateral renal function.Ureter bracket need to be routinely retained in patient's body necessarily Time.But the use of ureter bracket is often accompanied with some complication.Ureter bracket during indwelling can and body fluid with And the various hydrophilic or lipophilic group crosslinking that urine is contained within, agglomerate is formed, cot is such as formed, cause inadequate drainage even to hinder Plug, need to change again;The outer surface of ureter bracket can also stimulate surrounding tissue, produce inflammatory reaction, and serious causes and week Enclose tissue and produce adhesion, the place of inserting is become narrow;After overlong time is inserted, the inside and outside table of bacterium, fungi in ureter bracket Face is colonized, growth, causes organism infection.Urine reflux during rami ureterici mounts pipe then often leads to patient's pain in the back, the soreness of waist Deng can also increase the risk of urinary tract infections.These complication largely influence disease therapeuticing effect and the life of patient Quality.
Chinese patent literature CN201020509411.0, day for announcing 2011.03.02, disclose a kind of unidirectional drainage urine output Pipe holder pipe, is from up to down sequentially made up of, in ureter renal plevis section, urine output pipeline section, tubal bladder linkage section and bladder section Unidirectional drainage device is provided with the conduit of bladder linkage section, the unidirectional drainage device is a resilient rectangular rubber of tool Flat tube, it is circle that its openend struts, and is fixed on the pipe inner wall of tubal bladder linkage section, and closed end is placed in bladder section Side, upper and lower tube wall overlaps closed together.The correct indwelling of unidirectional drainage ureter stent of the utility model is urinated after in vivo Liquid can only enter bladder from renal plevis and urine output Tube Drain, and urine is backflowed without normal direction renal plevis and ureter in bladder.Chinese patent literature CN201420827018.4, day for announcing 2015.06.17, disclose a kind of anti-reflux ureter rack tube, including a hollow tube Body, the hollow tube has straight length, the first crimping segment and the second crimping segment, is provided with least on first crimping segment One surround the tube wall of first crimping segment and the elastic tubular film of the urine outlet can be completely covered, in the elastic tube Shape film is provided with least one opening opened when the elastic tubular film internal pressure is more than external pressure.The utility model The anti-reflux ureter rack tube for being provided is provided with elastic tubular film on the outside of the urine outlet of its first crimping segment, works as elastic tube When pressure inside shape film is more than outside pressure, the opening is opened, can be by this by the liquid flowed out in ureter rack tube Opening discharge;When pressure outside elastic tubular film is more than internal pressure, opening closure, so as to avoid intravesical urine Liquid reflux is returned in renal plevis, causes the secondary injury to patient.But both ureter brackets be all by increase component come Anti-reflux purpose is reached, if on the one hand component deformation then causes anti-reflux effect to weaken significantly, another aspect component increases With body fluid or the contact surface of urine, easily trigger and block and infect.
In sum, needing one kind badly can be effectively anti-reflux, especially avoids with body fluid, urine contact to prevent drainage not Freely, the ureter bracket of tissue adhesion and courses of infection.But relevant report is had no at present.
The content of the invention
The purpose of the present invention is directed to deficiency of the prior art, there is provided one kind can be effectively anti-reflux, especially avoid with Body fluid, urine contact are preventing inadequate drainage, tissue adhesion and the ureter bracket of courses of infection.
To achieve the above object, the present invention is adopted the technical scheme that:
A kind of ureter bracket, described ureter bracket is tubular body, be sequentially provided with kidney end part, partial ureter and Bladder end part;Described kidney end part is in curly, and distal end end face is opening;Described bladder end part is also in curling Shape, proximal face is closing;Described kidney end part and the inside of partial ureter are all hollow, and outer wall is provided with some Staggered conduction hole;The conduction hole of most proximal end is 3-10cm with the distance of bladder end part;Described ureter bracket Inner surface and outer surface are equipped with hydrophobic oleophobic layer.
Described hydrophobic oleophobic thickness degree is 50-200nm.
The a diameter of 1-3mm of described ureter bracket.
Adjacent conduction hole distance is 0.5-1mm, a diameter of 0.4-1mm of described conduction hole.
The proximal face shape in curved surface of described bladder end part.
The invention has the advantages that:
1st, ureter bracket surface of the invention is provided with hydrophobic oleophobic layer, and it forms on the surface of ureter bracket and protects together Cuticula, body fluid, urine and ureter bracket are isolated, and prevent surface attachment fibrin therein, the knot of ureter bracket Stone etc. and block, it is to avoid inadequate drainage and change the trouble of support, at the same avoid ureter bracket and surrounding tissue adhesion, Inflammatory reaction and the place of inserting is produced to become narrow risk, and also with the anti-infection effect for preventing germ to be colonized.And it is described Hydrophobic oleophobic thickness degree be 50-500nm, good buffer action can be played, can with the surface strong bonded of ureter bracket, And ureter bracket overall diameter will not be made excessive and influence anti-reflux effect and increase to insert difficulty, will not also make rami ureterici The interior diameter of frame is too small and causes inadequate drainage.
2nd, its bladder end part of ureter bracket of the invention is completely enclosed, and conduction hole and bladder end part have necessarily Distance, and ureter bracket integral diameter is smaller, therefore can effectively prevent urine reflux in bladder, and ensure that higher drawing Stream efficiency.
3rd, the proximal face of bladder end part shape in curved surface, can avoid that patient is caused to damage.
4th, kidney end part and bladder end part can effectively prevent ureter bracket from shifting all in curly.
Brief description of the drawings
Fig. 1 is ureter bracket structural representation of the invention.
Fig. 2 is hydrophobic oleophobic Rotating fields schematic diagram.
Specific embodiment
The specific embodiment that the present invention is provided is elaborated below in conjunction with the accompanying drawings.
The reference and part being related in accompanying drawing are as follows:
1. the partial ureter of kidney end part 2.
3. the conduction hole of bladder end part 4.
5. hydrophobic oleophobic layer
Embodiment 1
Fig. 1 is referred to, Fig. 1 is ureter bracket structural representation of the invention.Described ureter bracket is generally thin Tubular body, a diameter of 1-3mm is sequentially provided with kidney end part 1, partial ureter 2 and bladder end part 3.Described kidney end 1 is divided to be in curly, distal end end face is opening.Described bladder end part 3 is also in curly, and proximal face is closing, end The hemispherical curved in face.Described kidney end part 1 and the inside of partial ureter 2 are all hollow, and outer wall is provided with friendship The conduction hole 4 of mistake arrangement, adjacent conduction hole distance is 0.5-1mm, a diameter of 0.4-1mm of conduction hole 4.The conduction hole of most proximal end 4 distance apart from bladder end part 3 is 3-10cm.
Fig. 2 is referred to, Fig. 2 is hydrophobic oleophobic Rotating fields schematic diagram.The inner surface of described ureter bracket and outer surface Hydrophobic oleophobic layer 5 is equipped with, described hydrophobic oleophobic 5 thickness of layer are 50-200nm.
It should be noted that the effect of described hydrophobic oleophobic layer 5 is formed together in the inner and outer surfaces of ureter bracket Diaphragm, the surface of body fluid, urine and ureter bracket is separated by, it is therefore prevented that body fluid, urine are directly contacted with it, and then are prevented Surface attachment fibrin therein, calculus of ureter bracket etc. and block, it is to avoid inadequate drainage and change the fiber crops of support It is tired;Also avoid ureter bracket and surrounding tissue adhesion, produce inflammatory reaction and the place of inserting to become narrow risk, and have Prevent bacterium, fungi to be colonized, reach anti-infectious effect.Described hydrophobic oleophobic thickness degree is preferably 50-500nm, the specification Show that good buffer action can be played according to clinical verification, and be able to will not make with the surface strong bonded of ureter bracket The overall diameter of ureter bracket is excessive and reduce anti-reflux effect and difficulty is inserted in increase, will not also make the interior straight of ureter bracket Footpath is too small and causes inadequate drainage.Described hydrophobic oleophobic layer 5 is preferably the composite Nano coating with super-hydrophobic oleophobic property, its Material can be fluorine-containing nanometer polymer, such as fluorine carbon-nano polymer, silicon fluoride nanometer polymer, fluorine molybdenum nanometer polymer Deng, can using plasma coating technique be allowed to be deposited on the surface of ureter bracket.The near-end end of described bladder end part 3 Face is set to closing, and its outer wall is completely enclosed, can effectively prevent intravesical urine from passing through ureter reflux.Institute The diameter of the ureter bracket stated is set to 1-3mm, and diameter is smaller, can reduce the stimulation for Ureteral orifice end, utilizes The anti-reflux mechanism of ureter itself plays anti-reflux effect.The distal end end face of described kidney end part 1 is to be open, and outer wall Conduction hole 4 is set, is that, for drainage of urine, described conduction hole 4 is staggered, and diameter is set to 0.4-1mm, can be notable Improve drainage efficiency.Distance of the conduction hole 4 of most proximal end apart from bladder end part 3 is set to 3-10cm, can effectively prevent urine output Pipe is slight to be moved down and causes in bladder urine from conduction hole 4 and reflux, on the other hand also assures that possess more drawing on ureter Discharge orifice 4, it is ensured that preferable drainage effect.Described kidney end part 1 and bladder end part 3 in curly, can make the present invention Ureter fix well, prevent displacement.The proximal face of described bladder end part 3 is set to curved, can anti-not-go-end Portion's injured patient's bladder body.
Under ureter bracket working condition of the invention, described kidney end part 1 is located in kidney, described urine output pipe portion 2 are divided to be located in ureter, described bladder end part 3 is then in bladder.It can be well isolated from body fluid, urine, it is to avoid right The stimulation and the field planting of germ of surrounding tissue, possess anti-reflux function, and drainage is unobstructed, can effectively reduce the generation of complication.
Also, it should be noted that the design in equipment surfaces design hydrophobic oleophobic layer of the invention is not limited only to the present invention. Apply also for following apparatus:1st, chamber scope, including digestive endoscopy (gastroscope, enteroscope, Sigmoidoscope, choledochoscope etc.), thoracoscope, Laparoscope, cystoscope and joint of vertebral column mirror etc.;2nd, chamber Insertion, including intrathoracic drain, peritoneal cavity drainage tube, catheter, courage Pipe holder, nerve trachea, nose bile duct, stomach jejunum pipe etc.;3rd, blood vessel inserts thing, and mainly various vessel catheters, seal wire, blood vessel are replaced For thing and various intravascular stents, vessel catheter includes that various arterio-venous catheters, hemodialysis catheter, ECMO insert arterio-venous catheter Include various artificial blood vessels Deng, replacement vessels, intravascular stent includes inserting the various supports of blood vessel, such as cardiac coronary-artery Deng.Reach the purpose of isolation body fluid or drain or nutrient solution or blood.
The above is only the preferred embodiment of the present invention, it is noted that for the ordinary skill people of the art Member, on the premise of the inventive method is not departed from, can also make some improvement and supplement, and these are improved and supplement also should be regarded as Protection scope of the present invention.

Claims (5)

1. a kind of anti-reflux ureter bracket of super-hydrophobic oleophobic, it is characterised in that described ureter bracket is tubular body, according to It is secondary to be provided with kidney end part, partial ureter and bladder end part;Described kidney end part is in curly, and distal end end face is opening 's;Described bladder end part is also in curly, and proximal face is closing;Described kidney end part and partial ureter it is interior Portion is all hollow, and outer wall is provided with some staggered conduction holes;The conduction hole of most proximal end and the distance of bladder end part It is 3-10cm;The inner surface of described ureter bracket and outer surface are equipped with hydrophobic oleophobic layer.
2. ureter bracket according to claim 1, it is characterised in that described hydrophobic oleophobic thickness degree is 50- 200nm。
3. ureter bracket according to claim 1, it is characterised in that a diameter of 1-3mm of described ureter bracket.
4. ureter bracket according to claim 1, it is characterised in that adjacent conduction hole distance is 0.5-1mm, described The a diameter of 0.4-1mm of conduction hole.
5. ureter bracket according to claim 1, it is characterised in that the proximal face of described bladder end part is in song Planar.
CN201710169126.5A 2017-03-21 2017-03-21 A kind of anti-reflux ureter bracket of super-hydrophobic oleophobic Pending CN106924864A (en)

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Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107952157A (en) * 2017-12-12 2018-04-24 上海英诺伟医疗器械有限公司 A kind of Double-layer drainage tube
CN109513096A (en) * 2018-08-13 2019-03-26 孙磊 A kind of body cavity drainage tube
WO2022260316A1 (en) * 2021-06-07 2022-12-15 인제대학교 산학협력단 Internal drainage catheter for ascites drainage
WO2023217269A1 (en) * 2022-05-13 2023-11-16 广州维力医疗器械股份有限公司 Stent and implantation device thereof

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GB0706532D0 (en) * 2007-04-04 2007-05-09 Camstent Ltd Mbe Coated medical devices
CN204394746U (en) * 2014-12-22 2015-06-17 深圳市人民医院 A kind of anti-reflux ureter rack tube
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CN204563256U (en) * 2015-04-13 2015-08-19 深圳市人民医院 Ureter rack tube
CN207401003U (en) * 2017-03-21 2018-05-25 上海市第一人民医院 A kind of ureter bracket

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6071266A (en) * 1996-04-26 2000-06-06 Kelley; Donald W. Lubricious medical devices
US20050015076A1 (en) * 2003-06-27 2005-01-20 Inmed Corporation Catheter application system
GB0706532D0 (en) * 2007-04-04 2007-05-09 Camstent Ltd Mbe Coated medical devices
CN204394746U (en) * 2014-12-22 2015-06-17 深圳市人民医院 A kind of anti-reflux ureter rack tube
CN104758097A (en) * 2015-03-26 2015-07-08 中国人民解放军第二军医大学 Anti-backflow ureter support
CN204563256U (en) * 2015-04-13 2015-08-19 深圳市人民医院 Ureter rack tube
CN207401003U (en) * 2017-03-21 2018-05-25 上海市第一人民医院 A kind of ureter bracket

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107952157A (en) * 2017-12-12 2018-04-24 上海英诺伟医疗器械有限公司 A kind of Double-layer drainage tube
CN109513096A (en) * 2018-08-13 2019-03-26 孙磊 A kind of body cavity drainage tube
CN109513096B (en) * 2018-08-13 2021-09-14 孙磊 Body cavity drainage tube
WO2022260316A1 (en) * 2021-06-07 2022-12-15 인제대학교 산학협력단 Internal drainage catheter for ascites drainage
WO2023217269A1 (en) * 2022-05-13 2023-11-16 广州维力医疗器械股份有限公司 Stent and implantation device thereof

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Application publication date: 20170707

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