CN109125573A - A kind of Chinese medicine composition and preparation method thereof for treating light lip fish bacterial gill - Google Patents

A kind of Chinese medicine composition and preparation method thereof for treating light lip fish bacterial gill Download PDF

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Publication number
CN109125573A
CN109125573A CN201811381518.9A CN201811381518A CN109125573A CN 109125573 A CN109125573 A CN 109125573A CN 201811381518 A CN201811381518 A CN 201811381518A CN 109125573 A CN109125573 A CN 109125573A
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parts
chinese medicine
medicine composition
vitamin
radix
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潘庭双
胡玉婷
凌俊
江河
段国庆
周华兴
张雅丽
徐金开
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Huangshan Dingxin Ecological Agriculture Development Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/481Astragalus (milkvetch)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • A61K31/05Phenols
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/365Lactones
    • A61K31/375Ascorbic acid, i.e. vitamin C; Salts thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/284Atractylodes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539Scutellaria (skullcap)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/808Scrophularia (figwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8964Anemarrhena
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
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Abstract

The invention discloses a kind of Chinese medicine compositions and preparation method thereof for treating light lip fish bacterial gill, Chinese medicine composition includes the component of following parts by weight: 5-7 parts of Radix Astragali, 2-5 parts of Rhizoma Atractylodis Macrocephalae, 2-4 parts of radix scutellariae, 2-3 parts of radix scrophulariae, 1-3 parts of dandelion, 1-2 parts of honeysuckle, 0.5-1.5 parts of rhizoma anemarrhenae, 0.5-1 parts of Radix Glycyrrhizae, Chinese medicine composition further includes vitamin C and vitamin K;Preparation method is the following steps are included: drying, cutting, crush, being uniformly mixed.The present invention is the special-purpose medicaments for treating the bacillary rotten disease of light lip fish, has effects that sterilization, invigorating the spleen, cool blood, improves immunity;Drug is the Chinese medicine powder as made of purification of tcm, is had no toxic side effect to light lip fish;Vitamin C, K are fast in light lip fish body intracellular metabolite in drug, noresidue;Preparation process is easy to operate, stablizes feasible, is suitable for industrialized production, can efficiently prevent and treat light lip fish bacterial gill.

Description

A kind of Chinese medicine composition and preparation method thereof for treating light lip fish bacterial gill
Technical field
The invention belongs to the field of Chinese medicines more particularly to a kind of Chinese medicine composition for treating light lip fish bacterial gill and its Preparation method.
Background technique
Light lip fish (Acrossocheilus fasciatus) belongs to the Barbinae in Cyprinidae, and the body of general adult is grown 18cm or so, side have 6 vertical stripes, are mainly distributed in the streams of south China.Light lip fish is small-sized economic fish, Meat is delicious, while because its body colour is bright-coloured, is also used as fancy fishes, has considerable economic value.However, light lip fish is manually being supported During growing, due to the acute variation of the physical and chemical factors such as water body dissolved oxygen, ammonia nitrogen, nitrite and water temperature, it is easier to that fish body is caused to be exempted from The decline of epidemic disease power, superfine bacterial infection cause gill rot, cause mortality.
Drug is to the control efficiency of light lip fish bacterial gill, and domestic there is not been reported.Florfenicol, azithromycin, Certain therapeutic effect that has to bacterial gill such as orfloxacin, Enrofloxacin, chlorine dioxide, penta 2 an aromatic plant metioned in ancient books, formaldehyde, but effect is not It is ideal.And Chinese medicine is pure natural substance, the biological effective components containing there are many, such as saponin(e, alkaloid, tannin, has desinsection, resists Bacterium, antiviral, less toxic or nontoxic, low-residual or noresidue are not likely to produce the advantages that drug resistance.Therefore, for light lip fish bacterium The prevention and treatment of property fin rot, Chinese herbal medicine is preferably to select.
Summary of the invention
It is an object of the invention to overcome problem above of the existing technology, provide that a kind of to treat light lip fish bacillary rotten The Chinese medicine composition and preparation method thereof of gill disease can efficiently prevent and treat light lip fish bacterial gill.
To realize above-mentioned technical purpose and the technique effect, the invention is realized by the following technical scheme:
A kind of Chinese medicine composition for treating light lip fish bacterial gill, the Chinese medicine composition include following parts by weight Component: 5-7 parts of Radix Astragali, 2-5 parts of Rhizoma Atractylodis Macrocephalae, 2-4 parts of radix scutellariae, 2-3 parts of radix scrophulariae, 1-3 parts of dandelion, 1-2 parts of honeysuckle, rhizoma anemarrhenae 0.5-1.5 parts, 0.5-1 parts of Radix Glycyrrhizae.
Further, the Chinese medicine composition further includes vitamin C and vitamin K;
The ratio of the ascorbic quality and Chinese medicine composition gross mass is 1:500-1500;
The quality of the vitamin K and the ratio of Chinese medicine composition gross mass are 1:400-1000.
The present invention also provides a kind of preparation method of Chinese medicine composition for treating light lip fish bacterial gill, the preparations Method the following steps are included:
Step 1: by eight kinds of Radix Astragali, Rhizoma Atractylodis Macrocephalae, radix scutellariae, radix scrophulariae, dandelion, honeysuckle, rhizoma anemarrhenae, Radix Glycyrrhizae medicinal materials in 105 DEG C of rings It is dried under border;
Step 2: electric heating drying is carried out to eight kinds of medicinal materials until raw medicine moisture is lower than 5%;
Step 3: the medicinal material dried being sliced, and is crushed with pulverizer, then crosses 60 mesh steel sieve;
Step 4: proportionally selection addition is carried out to eight kinds of medicinal materials respectively, and is uniformly mixed by blender, eight kinds of medicines The proportion of material are as follows: 5-7 parts of Radix Astragali, 2-5 parts of Rhizoma Atractylodis Macrocephalae, 2-4 parts of radix scutellariae, 2-3 parts of radix scrophulariae, 1-3 parts of dandelion, 1-2 parts of honeysuckle, know It is 0.5-1.5 parts female, 0.5-1 parts of Radix Glycyrrhizae.
Further, also selection is added with vitamin C and vitamin K in the step 4, by vitamin C and vitamin K It is uniformly mixed with eight kinds of medicinal materials with blender, Chinese medicine powder is made in subpackage encapsulation.
Further, the Chinese medicine powder is added in light lip fish meal according to the dosage of light lip fish meal weight 1-2%, One course for the treatment of is fed 7 times, continuous feeding seven days, feeding 1 time daily.
The medicinal property of eight kinds of medicinal materials is as follows:
Radix Astragali, anti-aging, enhancing body's immunity, liver protection, diuresis, resisting stress and wide antibacterial action.
Rhizoma Atractylodis Macrocephalae, bitter is sweet, warm-natured, returns spleen, stomach meridian.Can transport spleen medicine, Wen Xinlie bitter in taste, have eliminating dampness, change it is turbid, relieve pain it Effect.
Radix scutellariae, it is bitter, cold in nature, there are heat-clearing and damp-drying drug, purging fire for removing toxin, hemostasis, miscarriage prevention and other effects.Cure mainly warm heat disease, upper breathing The diseases such as road infection, cough with lung heat, neonatal jaundice caused by dampness-heat, pneumonia, dysentery, carbuncle swells furuncle sore.The clinical good anti-bacterial effect of radix scutellariae, and do not produce Raw drug resistance.
Radix scrophulariae, clearing heat and cooling blood, nourishing yin and lessening fire, detoxicating and resolving a mass.Main warm heat disease heat and ying blood, the swelling and pain of throat larynx, skin sore.
Dandelion, nature and flavor are sweet, slight bitter, tremble with fear.Return liver, stomach meridian.There are diuresis, laxative, cholagogue and other effects.Control heat toxin, carbuncle swells, sore Ulcer, internal carbuncle, red eye, swell pain, damp and hot, furuncle swelling toxin, jaundice with damp-heat pathogen, puckery pain of heat gonorrhea.Control acute mastitis, adenolymphitis serious case of furuncle sore It is swollen.
Honeysuckle, it is cold in nature, it is sweet in flavor, enter lung, the heart, stomach meridian, to various pathogens such as hemolytic streptococcus, Staphylococcus aureus And infection of the upper respiratory tract Causative virus etc. has stronger restraint, has effects that clearing heat and detoxicating, anti-inflammatory, qi-restoratives treats wind, cures mainly Disease, warm disease heating under turgor, the diseases such as heat toxin large carbuncle and tumour.
Rhizoma anemarrhenae, property bitter cold have the benefits of nourishing yin and lessening fire, moisturizing dryness and lubricating intestine, sharp stool and urine.Belong to gunpowder under heat-clearing, the major functions: warm Disease.
Radix Glycyrrhizae, anti-inflammatory, antiulcer, antianaphylaxis, anticancer, antibacterial is antiviral, promotes pancreatic secretion, adjusts immune function Energy.
The beneficial effects of the present invention are:
1, the present invention is the special-purpose medicaments of the treatment bacillary rotten disease of light lip fish, has sterilization, invigorating the spleen, cool blood, raising immune The effect of power;
2, drug of the present invention is the Chinese medicine powder as made of purification of tcm, is had no toxic side effect to light lip fish;
3, vitamin C, K are fast in light lip fish body intracellular metabolite in drug of the present invention, noresidue;
4, present invention process is easy to operate, stablizes feasible, is suitable for industrialized production, can efficiently prevent and treat light lip fish Bacterial gill.
Specific embodiment
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common Technical staff's all other embodiment obtained without creative efforts belongs to the model that the present invention protects It encloses.
Embodiment 1:
A kind of Chinese medicine composition for treating light lip fish bacterial gill, Chinese medicine composition include the group of following parts by weight Point: 5 parts of Radix Astragali, 3 parts of Rhizoma Atractylodis Macrocephalae, 3 parts of radix scutellariae, 2 parts of radix scrophulariae, 2 parts of dandelion, 1 part of honeysuckle, 1 part of rhizoma anemarrhenae, 0.5 part of Radix Glycyrrhizae.
Chinese medicine composition further includes vitamin C and vitamin K;The ratio of ascorbic quality and Chinese medicine composition gross mass Example is 1:500;The quality of vitamin K and the ratio of Chinese medicine composition gross mass are 1:400.
Embodiment 2:
A kind of Chinese medicine composition for treating light lip fish bacterial gill, Chinese medicine composition include the group of following parts by weight Point: 7 parts of Radix Astragali, 2 parts of Rhizoma Atractylodis Macrocephalae, 2 parts of radix scutellariae, 3 parts of radix scrophulariae, 1 part of dandelion, 2 parts of honeysuckle, 1.5 parts of rhizoma anemarrhenae, 1 part of Radix Glycyrrhizae.
Chinese medicine composition further includes vitamin C and vitamin K;The ratio of ascorbic quality and Chinese medicine composition gross mass Example is 1:1500;The quality of vitamin K and the ratio of Chinese medicine composition gross mass are 1:1000.
Embodiment 3:
A kind of Chinese medicine composition for treating light lip fish bacterial gill, Chinese medicine composition include the group of following parts by weight Point: 6 parts of Radix Astragali, 5 parts of Rhizoma Atractylodis Macrocephalae, 4 parts of radix scutellariae, 2.5 parts of radix scrophulariae, 3 parts of dandelion, 1.5 parts of honeysuckle, 0.5 part of rhizoma anemarrhenae, Radix Glycyrrhizae 0.75 Part.
Chinese medicine composition further includes vitamin C and vitamin K;The ratio of ascorbic quality and Chinese medicine composition gross mass Example is 1:1000;The quality of vitamin K and the ratio of Chinese medicine composition gross mass are 1:700.
Embodiment 4:
The present invention also provides a kind of preparation method of Chinese medicine composition for treating light lip fish bacterial gill, preparation methods The following steps are included:
Step 1: by eight kinds of Radix Astragali, Rhizoma Atractylodis Macrocephalae, radix scutellariae, radix scrophulariae, dandelion, honeysuckle, rhizoma anemarrhenae, Radix Glycyrrhizae medicinal materials in 105 DEG C of rings It is dried under border;
Step 2: electric heating drying is carried out to eight kinds of medicinal materials until raw medicine moisture is lower than 5%;
Step 3: the medicinal material dried being sliced, and is crushed with pulverizer, then crosses 60 mesh steel sieve;
Step 4: proportionally selection addition is carried out to eight kinds of medicinal materials respectively, and is uniformly mixed by blender, eight kinds of medicines The proportion of material are as follows: 5 parts of Radix Astragali, 3 parts of Rhizoma Atractylodis Macrocephalae, 3 parts of radix scutellariae, 2 parts of radix scrophulariae, 2 parts of dandelion, 1 part of honeysuckle, 1 part of rhizoma anemarrhenae, Radix Glycyrrhizae 0.5 part.
Also selection is added with vitamin C and vitamin K in step 4, by vitamin C and vitamin K and eight kinds of medicinal materials with stirring It mixes machine to be uniformly mixed, Chinese medicine powder is made in subpackage encapsulation;Chinese medicine powder is added to according to the dosage of light lip fish meal weight 1-2% In light lip fish meal, a course for the treatment of is fed 7 times, continuous feeding seven days, feeding 1 time daily.
The basic principles, main features and advantages of the present invention have been shown and described above.The technology of the industry Personnel are it should be appreciated that the present invention is not limited to the above embodiments, and the above embodiments and description only describe this The principle of invention, without departing from the spirit and scope of the present invention, various changes and improvements may be made to the invention, these changes Change and improvement all fall within the protetion scope of the claimed invention.

Claims (5)

1. a kind of Chinese medicine composition for treating light lip fish bacterial gill, it is characterised in that: the Chinese medicine composition include with The component of lower parts by weight: 5-7 parts of Radix Astragali, 2-5 parts of Rhizoma Atractylodis Macrocephalae, 2-4 parts of radix scutellariae, 2-3 parts of radix scrophulariae, 1-3 parts of dandelion, honeysuckle 1- 2 parts, 0.5-1.5 parts of rhizoma anemarrhenae, 0.5-1 parts of Radix Glycyrrhizae.
2. a kind of Chinese medicine composition for treating light lip fish bacterial gill according to claim 1, it is characterised in that: institute Stating Chinese medicine composition further includes vitamin C and vitamin K;
The ratio of the ascorbic quality and Chinese medicine composition gross mass is 1:500-1500;
The quality of the vitamin K and the ratio of Chinese medicine composition gross mass are 1:400-1000.
3. a kind of preparation method for the Chinese medicine composition for treating light lip fish bacterial gill, it is characterised in that: the preparation side Method the following steps are included:
Step 1: by eight kinds of Radix Astragali, Rhizoma Atractylodis Macrocephalae, radix scutellariae, radix scrophulariae, dandelion, honeysuckle, rhizoma anemarrhenae, Radix Glycyrrhizae medicinal materials under 105 DEG C of environment It is dried;
Step 2: electric heating drying is carried out to eight kinds of medicinal materials until raw medicine moisture is lower than 5%;
Step 3: the medicinal material dried being sliced, and is crushed with pulverizer, then crosses 60 mesh steel sieve;
Step 4: proportionally carrying out selection addition to eight kinds of medicinal materials respectively, and is uniformly mixed by blender, eight kinds of medicinal materials Proportion are as follows: 5-7 parts of Radix Astragali, 2-5 parts of Rhizoma Atractylodis Macrocephalae, 2-4 parts of radix scutellariae, 2-3 parts of radix scrophulariae, 1-3 parts of dandelion, 1-2 parts of honeysuckle, rhizoma anemarrhenae 0.5-1.5 parts, 0.5-1 parts of Radix Glycyrrhizae.
4. a kind of preparation method of Chinese medicine composition for treating light lip fish bacterial gill according to claim 3, Be characterized in that: also selection is added with vitamin C and vitamin K in the step 4, by vitamin C and vitamin K and eight kinds of medicines Material is uniformly mixed with blender, and Chinese medicine powder is made in subpackage encapsulation.
5. a kind of preparation method of Chinese medicine composition for controlling bacterial gill according to claim 4, it is characterised in that: The Chinese medicine powder is added in light lip fish meal according to the dosage of light lip fish meal weight 1-2%, and a course for the treatment of is fed 7 times, Continuous feeding seven days, daily feeding 1 time.
CN201811381518.9A 2018-11-20 2018-11-20 A kind of Chinese medicine composition and preparation method thereof for treating light lip fish bacterial gill Pending CN109125573A (en)

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Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1644077A (en) * 2005-01-11 2005-07-27 冯绍宽 Plant additive premixed forage for aquatic culture and bait therefrom
CN105194231A (en) * 2015-09-15 2015-12-30 青岛海之源智能技术有限公司 Chinese herb feed additive for preventing bacterial gill-rot disease of fancy carps and preparation method thereof
CN105434706A (en) * 2016-01-18 2016-03-30 张嗣喜 Traditional Chinese medicine composition for treating gill rote disease of fish
CN107375575A (en) * 2017-08-04 2017-11-24 安徽省泾县丰瑞水产科技有限公司 A kind of Chinese herbal medicine for treating sturgeon fin rot and preparation method thereof

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1644077A (en) * 2005-01-11 2005-07-27 冯绍宽 Plant additive premixed forage for aquatic culture and bait therefrom
CN105194231A (en) * 2015-09-15 2015-12-30 青岛海之源智能技术有限公司 Chinese herb feed additive for preventing bacterial gill-rot disease of fancy carps and preparation method thereof
CN105434706A (en) * 2016-01-18 2016-03-30 张嗣喜 Traditional Chinese medicine composition for treating gill rote disease of fish
CN107375575A (en) * 2017-08-04 2017-11-24 安徽省泾县丰瑞水产科技有限公司 A kind of Chinese herbal medicine for treating sturgeon fin rot and preparation method thereof

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Application publication date: 20190104