CN109125426A - A kind of Chinese medicine for treating Decompensated cirrhosis - Google Patents

A kind of Chinese medicine for treating Decompensated cirrhosis Download PDF

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CN109125426A
CN109125426A CN201811323348.9A CN201811323348A CN109125426A CN 109125426 A CN109125426 A CN 109125426A CN 201811323348 A CN201811323348 A CN 201811323348A CN 109125426 A CN109125426 A CN 109125426A
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张泽钧
丁恒亚
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02Algae
    • A61K36/03Phaeophycota or phaeophyta (brown algae), e.g. Fucus
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    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
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    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/537Salvia (sage)
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

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Abstract

The invention discloses a kind of Chinese medicines for treating Decompensated cirrhosis, medicine preparation including following parts by weight forms: the blood clam of 10-20 parts by weight, the thallus laminariae of 5-15 parts by weight, the Radix Salviae Miltiorrhizae of 5-15 parts by weight, the radix paeoniae rubra of 5-15 parts by weight, the motherwort of 10-20 parts by weight, the Radix Notoginseng of 5-10 parts by weight, the Radix Glycyrrhizae of 5-10 parts by weight.The present invention is according to traditional Chinese medical theory, and theoretical using diagnosis and treatment carries out Chinese prescription screening, and formula is scientific and reasonable, and configuration is simple, has no toxic side effect, curative effect is short, quick.We are using resolving hard lump, activating microcirculation and removing stasis medicinal as principle of reatment, for the patient of liver and spleen blood stasis defect type Decompensated cirrhosis, for its cause of disease and primary symptom, first based on resolving hard lump, supplemented by activating microcirculation and removing stasis medicinal, last swelling and pain relieving, perfect square have the effect of resolving hard lump, activating microcirculation and removing stasis medicinal, swelling and pain relieving.

Description

A kind of Chinese medicine for treating Decompensated cirrhosis
Technical field
The present invention relates to a kind of Chinese medicines for treating Decompensated cirrhosis, treat the liver and spleen blood stasis defect type compensatory phase more particularly to a kind of The Chinese medicine of cirrhosis.
Background technique
Cirrhosis is clinical common chronic progressive hepatopathy, by one or more causes of disease are long-term or repeated action formed Diffusivity hepatic lesion.Cirrhosis is divided into " accumulation " and " bulging " by Chinese medicine, and accumulation refers to Decompensated cirrhosis, and bulging, which refers to, loses generation Repay cirrhosis, bulging is that the state of an illness is further aggravated on the basis of accumulation.
There are many card types for Decompensated cirrhosis, and wherein liver and spleen blood stasis defect type Decompensated cirrhosis belongs to wherein more special One kind, liver and spleen blood stasis defect type have embodiment in cirrhosis compensatory phase and cirrhosis patients in decompensation, but since its primary symptom etc. is different Factor, the principle of reatment of the two but it is different.
Summary of the invention
In view of the deficiencies of the prior art, the present invention provides a kind of with strong points, at low cost, and quick, cure rate is high, nontoxic The Chinese medicine of the special treatment liver and spleen blood stasis defect type Decompensated cirrhosis of side effect.
The technical scheme is that being achieved: a kind of Chinese medicine for treating Decompensated cirrhosis, including following parts by weight Several medicine preparations form: the blood clam of 10-20 parts by weight, the thallus laminariae of 5-15 parts by weight, the Radix Salviae Miltiorrhizae of 5-15 parts by weight, The radix paeoniae rubra of 5-15 parts by weight, the motherwort of 10-20 parts by weight, the Radix Notoginseng of 5-10 parts by weight, 5-10 parts by weight it is sweet Grass.
Technical solution of the present invention can be achieved in that
A kind of Chinese medicine for treating Decompensated cirrhosis, the medicine preparation including following parts by weight form: watt of 15 parts by weight Stupefied son, the thallus laminariae of 10 parts by weight, the Radix Salviae Miltiorrhizae of 10 parts by weight, the radix paeoniae rubra of 10 parts by weight, the motherwort of 15 parts by weight, 8 The Radix Notoginseng of parts by weight, the Radix Glycyrrhizae of 7 parts by weight.
Chinese medicine of the invention the preparation method is as follows:
Step 1: blood clam is cleaned, and is dried, and is pulverized, spare;
Step 2: Radix Salviae Miltiorrhizae, radix paeoniae rubra, motherwort (dissection), Radix Notoginseng, Radix Glycyrrhizae are cleaned, is cleaned, is pulled out after being soaked in water, moisturize and cut Piece dries, spare;
Step 3: thallus laminariae is cleaned, and is rinsed, and is slightly dried in the air, and is cut wide silk, is dried, spare;
Step 4: adding suitable quantity of water to set in casserole step 1 stock of drugs and be fried boiling, and is added after truce standby in step 2 and step 3 It with drug, is decocted 10-20 minutes with small fire, pulling the dregs of a decoction out after cooling is patent medicine.
Application method: daily one pair of medicine, every pair of medicine can be decocted three times, be taken in three times, and early, middle and late once a dose before meals.It needs It takes 6-12 months.
The pharmacology of specific each drug ingedient is as follows:
Blood clam: it is salty, it puts down;Removing phlegm and blood stasis, resolving hard lump, hyperacidity and pain relief.
Thallus laminariae: it is salty, it trembles with fear;Resolving hard lump, dissolving phlegm, Li Shui.
Radix Salviae Miltiorrhizae: it is bitter, it is slightly cold;Promoting blood circulation, calming heart and tranquilizing mind, apocenosis, analgesic.
Radix paeoniae rubra: acid, hardship are cool;The row stasis of blood, analgesic, cool blood, detumescence.
Motherwort: it is bitter, pungent, it is slightly cold;Promoting blood circulation for regulating menstruation, inducing diuresis to remove edema.
Radix Notoginseng: sweet, slight bitter, temperature;Activating blood and removing stasis, hemostasis, swelling and pain relieving.
Radix Glycyrrhizae: sweet and neutral;It invigorates the spleen and benefits qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.
Function of the invention and the major functions: blood clam embodies we using resolving hard lump as the main of main direction in the present invention The rules for the treatment of are monarch drug in a prescription;The effect of thallus laminariae auxiliary blood clam reinforces its resolving hard lump, Radix Salviae Miltiorrhizae activating microcirculation and removing stasis medicinal has the function of analgesic again, is minister Medicine;Radix paeoniae rubra, motherwort, Radix Notoginseng three share activating microcirculation and removing stasis medicinal, swelling and pain relieving, are adjutant;Radix Glycyrrhizae not only coordinating the drug actions of a prescription, to make medicine, The effect of can also reinforcing prescription analgesic.
The effect of playing resolving hard lump, activating microcirculation and removing stasis medicinal altogether after all medicine collaborations.Though each drug of we plays resolving hard lump, work jointly The effect of blood stagnation resolvation, but emphasize particularly on different fields again, above-mentioned effect can be just played after all medicines share.Such as in we, radix paeoniae rubra, benefit are female Grass, Radix Notoginseng three's drug effect emphasize particularly on different fields, and any herbal medicine is individually put into activating microcirculation and removing stasis medicinal in prescription, the effect of swelling and pain relieving not Obviously, but after sharing play activating microcirculation and removing stasis medicinal, swelling and pain relieving altogether, and effect after sharing is much larger than this three herbal medicines list The addition of effect when in prescription is solely added.
Beneficial effects of the present invention: for the present invention according to traditional Chinese medical theory, theoretical using diagnosis and treatment carries out Chinese prescription Screening, formula is scientific and reasonable, and configuration is simple, has no toxic side effect, curative effect is short, quick.We are with resolving hard lump, activating microcirculation and removing stasis medicinal Principle of reatment, it is first to be with resolving hard lump for its cause of disease and primary symptom for the patient of liver and spleen blood stasis defect type Decompensated cirrhosis It leads, supplemented by activating microcirculation and removing stasis medicinal, last swelling and pain relieving, perfect square has the effect of resolving hard lump, activating microcirculation and removing stasis medicinal, swelling and pain relieving.
Specific embodiment
The present invention is described in further details with reference to embodiments:
Embodiment 1: a kind of Chinese medicine for treating liver and spleen blood stasis defect type Decompensated cirrhosis, by the medicine preparation of following weight grams At 10 grams of blood clam, 5 grams of thallus laminariae, 5 grams of Radix Salviae Miltiorrhizae, 5 grams of radix paeoniae rubra, 10 grams of motherwort, 5 grams of Radix Notoginseng, 5 grams sweet Grass.
Treat the Chinese medicine of liver and spleen blood stasis defect type Decompensated cirrhosis the preparation method is as follows:
Step 1: blood clam is cleaned, and is dried, and is pulverized, spare;
Step 2: Radix Salviae Miltiorrhizae, radix paeoniae rubra, motherwort (dissection), Radix Notoginseng, Radix Glycyrrhizae are cleaned, is cleaned, is pulled out after being soaked in water, moisturize and cut Piece dries, spare;
Step 3: thallus laminariae is cleaned, and is rinsed, and is slightly dried in the air, and is cut wide silk, is dried, spare;
Step 4: adding suitable quantity of water to set in casserole step 1 stock of drugs and be fried boiling, and is added after truce standby in step 2 and step 3 It with drug, is decocted 10-20 minutes with small fire, pulling the dregs of a decoction out after cooling is patent medicine.
Application method: daily one pair of medicine, every pair of medicine can be decocted three times, be taken in three times, and early, middle and late once a dose before meals.It needs It takes 6-12 months.
Embodiment 2: a kind of Chinese medicine for treating liver and spleen blood stasis defect type Decompensated cirrhosis, by the medicine preparation of following weight grams It forms: 20 grams of blood clam, 15 grams of thallus laminariae, 15 grams of Radix Salviae Miltiorrhizae, 15 grams of radix paeoniae rubra, 20 grams of motherwort, 10 grams of Radix Notoginseng, 10 Gram Radix Glycyrrhizae.
Treat the Chinese medicine of liver and spleen blood stasis defect type Decompensated cirrhosis the preparation method is as follows:
Step 1: blood clam is cleaned, and is dried, and is pulverized, spare;
Step 2: Radix Salviae Miltiorrhizae, radix paeoniae rubra, motherwort (dissection), Radix Notoginseng, Radix Glycyrrhizae are cleaned, is cleaned, is pulled out after being soaked in water, moisturize and cut Piece dries, spare;
Step 3: thallus laminariae is cleaned, and is rinsed, and is slightly dried in the air, and is cut wide silk, is dried, spare;
Step 4: adding suitable quantity of water to set in casserole step 1 stock of drugs and be fried boiling, and is added after truce standby in step 2 and step 3 It with drug, is decocted 10-20 minutes with small fire, pulling the dregs of a decoction out after cooling is patent medicine.
Application method: daily one pair of medicine, every pair of medicine can be decocted three times, be taken in three times, and early, middle and late once a dose before meals.It needs It takes 6-12 months.
Embodiment 3: a kind of Chinese medicine for treating liver and spleen blood stasis defect type Decompensated cirrhosis, by the medicine preparation of following weight grams It forms: 15 grams of blood clam, 10 grams of thallus laminariae, 10 grams of Radix Salviae Miltiorrhizae, 10 grams of radix paeoniae rubra, 15 grams of motherwort, 8 grams of Radix Notoginseng, 7 grams Radix Glycyrrhizae.
Treat the Chinese medicine of liver and spleen blood stasis defect type Decompensated cirrhosis the preparation method is as follows:
Step 1: blood clam is cleaned, and is dried, and is pulverized, spare;
Step 2: Radix Salviae Miltiorrhizae, radix paeoniae rubra, motherwort (dissection), Radix Notoginseng, Radix Glycyrrhizae are cleaned, is cleaned, is pulled out after being soaked in water, moisturize and cut Piece dries, spare;
Step 3: thallus laminariae is cleaned, and is rinsed, and is slightly dried in the air, and is cut wide silk, is dried, spare;
Step 4: adding suitable quantity of water to set in casserole step 1 stock of drugs and be fried boiling, and is added after truce standby in step 2 and step 3 It with drug, is decocted 10-20 minutes with small fire, pulling the dregs of a decoction out after cooling is patent medicine.
Application method: daily one pair of medicine, every pair of medicine can be decocted three times, be taken in three times, and early, middle and late once a dose before meals.It needs It takes 6-12 months.
Embodiment 4: a kind of Chinese medicine for treating liver and spleen blood stasis defect type Decompensated cirrhosis, by the medicine preparation of following weight grams It forms: 12 grams of blood clam, 9 grams of thallus laminariae, 9 grams of Radix Salviae Miltiorrhizae, 9 grams of radix paeoniae rubra, 12 grams of motherwort, 7 grams of Radix Notoginseng, 6 grams Radix Glycyrrhizae.
Treat the Chinese medicine of liver and spleen blood stasis defect type Decompensated cirrhosis the preparation method is as follows:
Step 1: blood clam is cleaned, and is dried, and is pulverized, spare;
Step 2: Radix Salviae Miltiorrhizae, radix paeoniae rubra, motherwort (dissection), Radix Notoginseng, Radix Glycyrrhizae are cleaned, is cleaned, is pulled out after being soaked in water, moisturize and cut Piece dries, spare;
Step 3: thallus laminariae is cleaned, and is rinsed, and is slightly dried in the air, and is cut wide silk, is dried, spare;
Step 4: adding suitable quantity of water to set in casserole step 1 stock of drugs and be fried boiling, and is added after truce standby in step 2 and step 3 It with drug, is decocted 10-20 minutes with small fire, pulling the dregs of a decoction out after cooling is patent medicine.
Application method: daily one pair of medicine, every pair of medicine can be decocted three times, be taken in three times, and early, middle and late once a dose before meals.It needs It takes 6-12 months.
The result of clinical observation of the present invention is as follows:
Effective cure rate of Chinese medicine of the invention counts, and criterion of therapeutical effect is as follows:
Cure: symptom, sign disappear;
Effective: symptom, sign disappearance make moderate progress;
Invalid: symptom, sign are without change.
The present invention treats patient totally 14 of the liver and spleen blood stasis defect type Decompensated cirrhosis for participating in statistics, in which: recovery from illness 7, Effective 5, invalid 2, total effective rate reaches 85% or more.
Typical case:
Connect so-and-so, male, 46 years old, abdomen had block, and shouting pain at side of body rib is on inspection Decompensated cirrhosis, treats by here, eight It fully recovers after a month.

Claims (3)

1. a kind of Chinese medicine for treating Decompensated cirrhosis, it is characterised in that: the medicine preparation including following parts by weight forms: The blood clam of 10-20 parts by weight, the thallus laminariae of 5-15 parts by weight, the Radix Salviae Miltiorrhizae of 5-15 parts by weight, 5-15 parts by weight it is red Chinese herbaceous peony, the motherwort of 10-20 parts by weight, the Radix Notoginseng of 5-10 parts by weight, the Radix Glycyrrhizae of 5-10 parts by weight.
2. a kind of Chinese medicine for treating Decompensated cirrhosis according to claim 1, it is characterised in that: including following parts by weight Several medicine preparations form: the blood clam of 15 parts by weight, the thallus laminariae of 10 parts by weight, the Radix Salviae Miltiorrhizae of 10 parts by weight, 10 weight The radix paeoniae rubra of number, the motherwort of 15 parts by weight, the Radix Notoginseng of 8 parts by weight, the Radix Glycyrrhizae of 7 parts by weight.
3. a kind of preparation method of the Chinese medicine for the treatment of Decompensated cirrhosis as claimed in claim 1 or 2, preparation method is such as Under:
Step 1: blood clam is cleaned, and is dried, and is pulverized, spare;
Step 2: Radix Salviae Miltiorrhizae, radix paeoniae rubra, motherwort (dissection), Radix Notoginseng, Radix Glycyrrhizae are cleaned, is cleaned, is pulled out after being soaked in water, moisturize and cut Piece dries, spare;
Step 3: thallus laminariae is cleaned, and is rinsed, and is slightly dried in the air, and is cut wide silk, is dried, spare;
Step 4: adding suitable quantity of water to set in casserole step 1 stock of drugs and be fried boiling, and is added after truce standby in step 2 and step 3 It with drug, is decocted 10-20 minutes with small fire, pulling the dregs of a decoction out after cooling is patent medicine.
CN201811323348.9A 2018-11-08 2018-11-08 A kind of Chinese medicine for treating Decompensated cirrhosis Pending CN109125426A (en)

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Application Number Priority Date Filing Date Title
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111150826A (en) * 2020-02-17 2020-05-15 河南中医药大学 Traditional Chinese medicine for treating post-compensation hepatitis B cirrhosis

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN111150826A (en) * 2020-02-17 2020-05-15 河南中医药大学 Traditional Chinese medicine for treating post-compensation hepatitis B cirrhosis
CN111150826B (en) * 2020-02-17 2021-11-09 河南中医药大学 Traditional Chinese medicine for treating post-compensation hepatitis B cirrhosis

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Application publication date: 20190104