CN109125387A - 一种富含山核桃油中药提取物组合物和用途 - Google Patents
一种富含山核桃油中药提取物组合物和用途 Download PDFInfo
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- CN109125387A CN109125387A CN201811342110.0A CN201811342110A CN109125387A CN 109125387 A CN109125387 A CN 109125387A CN 201811342110 A CN201811342110 A CN 201811342110A CN 109125387 A CN109125387 A CN 109125387A
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Abstract
本发明涉及保健品加工领域。本发明公开了一种富含山核桃油中药提取物组合物，它是由以下配比原料制成：山核桃油10‑50g，人参150g，当归450g，川穹100g，黄芪550g。本发明利用山核桃油具有滋润肌肤、美容养颜、防止肌肤衰老等有益效果，与具有益气化瘀，调经祛斑，滋养肌肤作用的中药组合，对防治自由基对肌肤的损伤，促进血液循环，增进肌肤细胞发育具有较好的辅助防治效果。通过山核桃油与本发明中药组合的提取物组成新的药用组合物，强化了药物对皮肤损伤、色斑、癣疾病及皮肤色素沉着等具有良好的调理功能。所述的组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
Description
技术领域
本发明涉及药物制剂和/或保健食品加工领域，具体涉及一种由山核桃油和中药提取物组合物和用途。
背景技术
山核桃油，是一种最近很流行的木本植物油。山核桃油不仅仅一方面选取优质的山核桃作原料，而且是采用先进的工业制取出来，被誉为“东方橄榄油”。
山核桃油是采取山核桃果仁提炼出来的油。以传统的物理压榨方法精制而成，充分保留了山核桃果仁的原生态营养精华，具有山核桃果仁特有的坚果芳香味道，是一种高级木本植物营养油。
山核桃油是纯正的天然有机食品，1千克核桃油的营养价值约等于3千克精肉、5千克鸡蛋、9.5千克牛奶。山核桃油中含有丰富的亚麻酸，不饱和脂肪酸总量接近90%，并富含黄酮及维生素A、B1、B2、C、E及人体所需的Ca、Mg等微量元素。
山核桃油的理化性质
山核桃油的理化性质结果见表，与其他植物油相比较，山核桃油油体清亮，呈淡金黄色；山核桃油中单不饱和脂肪酸含量较多，使得其碘价相对较低；相对密度较低说明组成山核桃油的分子量小、不饱和度高；酸价低说明山核桃油中游离脂肪酸含量较少，油脂质量好。
山核桃油主要是榨取中保留山核桃中原有的营养价值和维生素，不饱和脂肪酸、亚油酸、亚麻酸以及富含天然的维生素以及营养物质对人体有非常好的功效，关于山核桃油的具体作用：
（1）山核桃油有强身健体的作用：这是由于山核桃能提供充足的热量。有数据测算，每100克的山核桃仁便可提供约630千卡的热量，相当于米饭热量的3-4倍。因此在冬天常吃些山核桃还可以起到御寒的作用。
（2）山核桃油有滋润皮肤的作用：山核桃油富含与皮肤亲和力极佳的角鲨和人体必须脂肪酸。吸收迅速，有效保持皮肤弹性和润泽。
（3）山核桃油有美容养颜的作用：这是由于山核桃油富含人体必需脂肪酸，同时还富含一种与皮肤亲和力很强的角鲨稀。这两种物质能迅速被皮肤所吸收，能有效保护皮肤的弹性和润泽；能消除面部皱纹，防止肌肤衰老。
（4）山核桃油还有秀美护发的作用：多吃山核桃油能促进小孩的头发变黑。
由于现代人们生活节奏加快，生活压力大，生活结构的变化，加之环境污染给现代生活中一些特有的疾病也相应的呈现增多趋势。如因气血不足，气血阻滞或气虚血瘀等所致的内分泌紊乱，黄褐斑（黧黑斑）、雀斑、蝴蝶斑，皮肤面黄粗糙等病例明显增加，直到目前也未有确切疗效的治疗药物。利用具有滋润肌肤、防止肌肤衰老等功效的山核桃油，结合我国传统的中医药理论，与具有益气化瘀，调经祛斑，滋养肌肤的中药组合，将山核桃油这种活性物质与传统医学和现代制药工艺技术有机结合，组成一种新的药物组合物，使该组合物能在上述疾病的治疗中起到辅助的防治作用。
发明内容
本发明的目的在于提供一种富含山核桃油中药提取物组合物。
本发明的目的还在于提供一种富含山核桃油中药提取物组合物在制备辅助调节益气化瘀、调经祛斑、滋养肌肤药物中作为制备保健品的用途。
本发明的目的还在于提供一种富含山核桃油中药提取物组合物在制备化妆品中的添加剂的用途。
本发明公开的一种富含山核桃油中药提取物组合物，其特征在于，它是由以下配比原料制成：山核桃油10-50g，人参150g，当归450g，川穹100g，黄芪550g，
其制备方法如下：取人参150g，当归450g，川穹100g，黄芪550g加入药材重量比10倍浓度为75％v/v的乙醇，在38℃-40℃下浸泡168小时，滤取浸泡提取液，回收乙醇得浸提液保存备用，另将药渣分别按药材重量8倍、5倍、3倍加水煎煮提取3次，煎煮提取时间为第一次2小时，第二次1小时，第三次0.5小时，合并三次煎煮提取液，经过滤、浓缩至比重为1.0的浓缩液时，再与上述回收乙醇后的浸提液合并混匀，经干燥至含水量为4-5％，得中药提取物，另将山核桃油按重量比为1:10的比例加入到乙醚中，充分混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使物料均匀，得混合物料，然后将混合物料置50℃吹风干燥使乙醚挥尽，即得中药提取物组合物。
本发明中所述的水，在没有作出特定说明时，均为纯化水。
上述所述的乙醚为药用级乙醚。
所述的药物组合物按常规工艺制成片剂、胶囊剂、颗粒剂作为制备保健品的用途。
所述的药物组合物作为制备酒制品的用途。
所述的药物组合物作为制备化妆品中的添加剂的用途。
人参，甘，微苦，微温。归脾、肺、心肾经。具有大补元气，复脉固脱，补脾益肺，生津养血、安神益智功能。人参大补元气，元气充则心气得养，心神得宁，心智得聪，而具安神益智的功效，用于治疗心气不足或心肾气虚、心脾两虚的失眠、健忘等。人参甘温，大补元气，益气以生血，具气血双补之效，故可用治脾胃气虚，化源不足，血虚萎黄之证。
当归，甘、辛，温。归肝、心、脾经。具有补血活血，调经止痛，润肠通便功能，用于血虚萎黄，眩晕心悸，月经不调，经闭痛经，虚寒腹痛，风湿痹痛，跌扑损伤，痈疽疮疡，肠燥便秘。当归甘温，养血补虚，为补血良药，故可用治心肝血虚，血色萎黄，眩晕心悸。
川穹，辛，温。归肝、胆、心包经。具有活血行气，祛风止痛功能。川穹辛散温通，功能活血行气，有“血中气药”（《本草汇言》）之称。既活血祛瘀通脉，善治心脉瘀阻、胸痹心痛；又行气开郁止痛，为肝郁气滞之胸肋刺痛所多用。川穹善于“下调经水”（《本草汇言》）、活血调经，优为月经不调、痛经、经闭等证之要药；亦治癥瘕腹痛，具有活血祛瘀、消癥散结之功。
黄芪，甘，微温。归肺、脾经。具有补气升阳，固表止汗，利水消肿，生津养血，行滞通痹，托毒排脓，敛疮生肌功效，用于气血乏力，食少便溏，中气下陷，腹泻脱肛，便血崩漏，表虚自汗，气虚水肿，内热消渴，气虚萎黄之证。黄芪甘微温，益气升阳，盖阳生阴长，气旺血生，故有补气生血之功，长用于劳倦内伤，气亏血虚，血虚阳浮，肌热面赤，脉大无力之血虚发热证。及思虑过度，劳伤心脾，气血双亏，面色萎黄，心悸失眠者。
以上4种中药组成制备提取物，按照中医药理论证明具有益气化瘀，调经祛斑，滋养肌肤作用，按现代中药理论研究，如组份中当归为主药之一，其有效成分阿魏酸能减少H2O2含量，并与磷脂酰乙醇胺结合抑制氧化反应和自由基反应，拮抗自由基对组织的损害，促进血液循环，增进肌肤细胞发育的作用。阿魏酸不仅能淬灭自由基。而且还能调节人体生理机制，抑制产生自由基的酶，促进清除自由基的酶的产生。
利用山核桃油活性成分与中药组合提取物能产生不同成分、不同作用机制的协同治疗作用，能强化其药物的抗氧化和清除自由基作用。本发明利用山核桃油具有滋润皮肤、美容养颜、防止肌肤衰老等的有益效果，与具有益气化瘀，调经祛斑，滋养肌肤作用的中药组合，对防治自由基对肌肤的损伤，促进血液循环，增进肌肤细胞发育具有较好的辅助防治效果。通过山核桃油与本发明中药组合的提取物组成新的药用组合物，能够充分发挥山核桃油成分和中药成分有益效果，强化了药物对皮肤损伤、色斑、癣疾病及皮肤色素沉着等具有良好的调理功能，为本发明药物组合物在保健食品、化妆品中的应用提供了理论基础。尤其是抗氧化、清除自由基、延缓皮肤衰老和身体机能调理功能更为显著，因此产品既可以作为保健食品内服食用或饮用，也可作为天然的美容护肤产品外用。本发明克服了目前中药组合成分功效不理想的问题，而且产品使用方便，口感较好，工艺简单，生产效率高，质量稳定，可广泛用于保健品、酒品、化妆品的生产。
本发明的药用组合物，可以根据需要配制成不同的口服剂型。可以将药用组合物与药学上可接受的辅料混合配制成片剂，胶囊剂，颗粒剂，酒制品等，其中胶囊剂可制备成软胶囊剂和硬胶囊剂；其中片剂优选泡腾片，咀嚼片，口含片，因为泡腾片，咀嚼片，口含片与普通片剂相比有以下几点优势：（1）服用方便，可嚼服、含服，可化水，由于配制这些片剂都要加入一定量的糖份作为赋形剂，因而口感好，人们乐意服用，泡腾片加水自溶后犹如一杯饮料，使人们乐于饮用；（2）吸收快，因为经口腔或泡饮使药物成分离子化，使之吸收快，生物利用度高；（3）便于携带，方便运输；其中所述的酒品可制成白酒、葡萄酒、黄酒和啤酒制品。本发明的药用组合物，还可以根据需要配制成化妆品。
具体实施方式
通过以下实施例是对本发明作进一步的说明，但对本发明的范围不构成任何限制。
实施例1
富含山核桃油中药提取物组合物的制备
分别称取净药材人参150g，当归450g，川穹100g，黄芪550g，置于提取罐中，加入浓度为75％的乙醇12.5kg，在40℃条件下密闭浸泡168小时，浸泡期间每隔6小时进行搅拌1次，浸泡结束后，滤取浸泡提取液，将浸泡提取液回收乙醇得浸提液另器保存备用；将醇浸提后的药渣加入纯净水10公斤，加热煎煮2小时，滤取煎煮液，药渣再加入纯净水6.25公斤，加热煎煮1小时，滤取煎煮液，再将药渣加纯净水3.75公斤，加热煎煮0.5小时，滤取煎煮液，将3次煎煮液合并，过滤，将滤液浓缩至比重为1.0的浓缩液时，再与上述浸提液合并，再进一步浓缩成稠膏后，置于真空干燥机内进行真空干燥至含水量为4.5％，即得中药提取物；称取山核桃油10g，加入100g的药用乙醚使溶，充分搅拌混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使均匀，得混合物料，然后将混合物料置50℃吹风干燥，使乙醚挥尽，过筛，即得。
所述的富含山核桃油中药提取物组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
实施例2
富含山核桃油中药提取物组合物的制备
分别称取净药材人参150g，当归450g，川穹100g，黄芪550g，置于提取罐中，加入浓度为75％的乙醇12.5kg，在40℃条件下密闭浸泡168小时，浸泡期间每隔6小时进行搅拌1次，浸泡结束后，滤取浸泡提取液，将浸泡提取液回收乙醇得浸提液另器保存备用；将醇浸提后的药渣加入纯净水10公斤，加热煎煮2小时，滤取煎煮液，药渣再加入纯净水6.25公斤，加热煎煮1小时，滤取煎煮液，再将药渣加纯净水3.75公斤，加热煎煮0.5小时，滤取煎煮液，将3次煎煮液合并，过滤，将滤液浓缩至比重为1.0的浓缩液时，再与上述浸提液合并，再进一步浓缩成稠膏后，置于真空干燥机内进行真空干燥至含水量为4.5％，即得中药提取物；称取山核桃油50g，加入500g的药用乙醚使溶，充分搅拌混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使均匀，得混合物料，然后将混合物料置50℃吹风干燥，使乙醚挥尽，过筛，即得。
所述的富含山核桃油中药提取物组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
实施例3
富含山核桃油中药提取物组合物的制备
分别称取净药材人参150g，当归450g，川穹100g，黄芪550g，置于提取罐中，加入浓度为75％的乙醇12.5kg，在40℃条件下密闭浸泡168小时，浸泡期间每隔6小时进行搅拌1次，浸泡结束后，滤取浸泡提取液，将浸泡提取液回收乙醇得浸提液另器保存备用；将醇浸提后的药渣加入纯净水10公斤，加热煎煮2小时，滤取煎煮液，药渣再加入纯净水6.25公斤，加热煎煮1小时，滤取煎煮液，再将药渣加纯净水3.75公斤，加热煎煮0.5小时，滤取煎煮液，将3次煎煮液合并，过滤，将滤液浓缩至比重为1.0的浓缩液时，再与上述浸提液合并，再进一步浓缩成稠膏后，置于真空干燥机内进行真空干燥至含水量为4.0％，即得中药提取物；称取山核桃油25g，加入250g的药用乙醚使溶，充分搅拌混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使均匀，得混合物料，然后将混合物料置50℃吹风干燥，使乙醚挥尽，过筛，即得。
所述的富含山核桃油中药提取物组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
实施例4
富含山核桃油中药提取物组合物的制备
分别称取净药材人参150g，当归450g，川穹100g，黄芪550g，置于提取罐中，加入浓度为75％的乙醇12.5kg，在38℃条件下密闭浸泡168小时，浸泡期间每隔6小时进行搅拌1次，浸泡结束后，滤取浸泡提取液，将浸泡提取液回收乙醇得浸提液另器保存备用；将醇浸提后的药渣加入纯净水10公斤，加热煎煮2小时，滤取煎煮液，药渣再加入纯净水6.25公斤，加热煎煮1小时，滤取煎煮液，再将药渣加纯净水3.75公斤，加热煎煮0.5小时，滤取煎煮液，将3次煎煮液合并，过滤，将滤液浓缩至比重为1.0的浓缩液时，再与上述浸提液合并，再进一步浓缩成稠膏后，置于真空干燥机内进行真空干燥至含水量为4.8％，即得中药提取物；称取山核桃油12g，加入120g的药用乙醚使溶，充分搅拌混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使均匀，得混合物料，然后将混合物料置50℃吹风干燥，使乙醚挥尽，过筛，即得。
所述的富含山核桃油中药提取物组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
实施例5
富含山核桃油中药提取物组合物的制备
分别称取净药材人参150g，当归450g，川穹100g，黄芪550g，置于提取罐中，加入浓度为75％的乙醇12.5kg，在38℃条件下密闭浸泡168小时，浸泡期间每隔6小时进行搅拌1次，浸泡结束后，滤取浸泡提取液，将浸泡提取液回收乙醇得浸提液另器保存备用；将醇浸提后的药渣加入纯净水10公斤，加热煎煮2小时，滤取煎煮液，药渣再加入纯净水6.25公斤，加热煎煮1小时，滤取煎煮液，再将药渣加纯净水3.75公斤，加热煎煮0.5小时，滤取煎煮液，将3次煎煮液合并，过滤，将滤液浓缩至比重为1.0的浓缩液时，再与上述浸提液合并，再进一步浓缩成稠膏后，置于真空干燥机内进行真空干燥至含水量为5.0％，即得中药提取物；称取山核桃油15g，加入150g的药用乙醚使溶，充分搅拌混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使均匀，得混合物料，然后将混合物料置50℃吹风干燥，使乙醚挥尽，过筛，即得。
所述的富含山核桃油中药提取物组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
实施例6
富含山核桃油中药提取物组合物的制备
分别称取净药材人参150g，当归450g，川穹100g，黄芪550g，置于提取罐中，加入浓度为75％的乙醇12.5kg，在38℃条件下密闭浸泡168小时，浸泡期间每隔6小时进行搅拌1次，浸泡结束后，滤取浸泡提取液，将浸泡提取液回收乙醇得浸提液另器保存备用；将醇浸提后的药渣加入纯净水10公斤，加热煎煮2小时，滤取煎煮液，药渣再加入纯净水6.25公斤，加热煎煮1小时，滤取煎煮液，再将药渣加纯净水3.75公斤，加热煎煮0.5小时，滤取煎煮液，将3次煎煮液合并，过滤，将滤液浓缩至比重为1.0的浓缩液时，再与上述浸提液合并，再进一步浓缩成稠膏后，置于真空干燥机内进行真空干燥至含水量为5.0％，即得中药提取物；称取山核桃油35g，加入350g的药用乙醚使溶，充分搅拌混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使均匀，得混合物料，然后将混合物料置50℃吹风干燥，使乙醚挥尽，过筛，即得。
所述的富含山核桃油中药提取物组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
实施例7
富含山核桃油中药提取物组合物的制备
分别称取净药材人参150g，当归450g，川穹100g，黄芪550g，置于提取罐中，加入浓度为75％的乙醇12.5kg，在42℃条件下密闭浸泡168小时，浸泡期间每隔6小时进行搅拌1次，浸泡结束后，滤取浸泡提取液，将浸泡提取液回收乙醇得浸提液另器保存备用；将醇浸提后的药渣加入纯净水10公斤，加热煎煮2小时，滤取煎煮液，药渣再加入纯净水6.25公斤，加热煎煮1小时，滤取煎煮液，再将药渣加纯净水3.75公斤，加热煎煮0.5小时，滤取煎煮液，将3次煎煮液合并，过滤，将滤液浓缩至比重为1.0的浓缩液时，再与上述浸提液合并，再进一步浓缩成稠膏后，置于真空干燥机内进行真空干燥至含水量为4.0％，即得中药提取物；称取山核桃油20g，加入200g的药用乙醚使溶，充分搅拌混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使均匀，得混合物料，然后将混合物料置50℃吹风干燥，使乙醚挥尽，过筛，即得。
所述的富含山核桃油中药提取物组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
实施例8
富含山核桃油中药提取物组合物的制备
分别称取净药材人参150g，当归450g，川穹100g，黄芪550g，置于提取罐中，加入浓度为75％的乙醇12.5kg，在42℃条件下密闭浸泡168小时，浸泡期间每隔6小时进行搅拌1次，浸泡结束后，滤取浸泡提取液，将浸泡提取液回收乙醇得浸提液另器保存备用；将醇浸提后的药渣加入纯净水10公斤，加热煎煮2小时，滤取煎煮液，药渣再加入纯净水6.25公斤，加热煎煮1小时，滤取煎煮液，再将药渣加纯净水3.75公斤，加热煎煮0.5小时，滤取煎煮液，将3次煎煮液合并，过滤，将滤液浓缩至比重为1.0的浓缩液时，再与上述浸提液合并，再进一步浓缩成稠膏后，置于真空干燥机内进行真空干燥至含水量为4.5％，即得中药提取物；称取山核桃油40g，加入400g的药用乙醚使溶，充分搅拌混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使均匀，得混合物料，然后将混合物料置50℃吹风干燥，使乙醚挥尽，过筛，即得。
所述的富含山核桃油中药提取物组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
实施例9
富含山核桃油中药提取物组合物的制备
分别称取净药材人参150g，当归450g，川穹100g，黄芪550g，置于提取罐中，加入浓度为75％的乙醇12.5kg，在42℃条件下密闭浸泡168小时，浸泡期间每隔6小时进行搅拌1次，浸泡结束后，滤取浸泡提取液，将浸泡提取液回收乙醇得浸提液另器保存备用；将醇浸提后的药渣加入纯净水10公斤，加热煎煮2小时，滤取煎煮液，药渣再加入纯净水6.25公斤，加热煎煮1小时，滤取煎煮液，再将药渣加纯净水3.75公斤，加热煎煮0.5小时，滤取煎煮液，将3次煎煮液合并，过滤，将滤液浓缩至比重为1.0的浓缩液时，再与上述浸提液合并，再进一步浓缩成稠膏后，置于真空干燥机内进行真空干燥至含水量为4.5％，即得中药提取物；称取山核桃油30g，加入300g的药用乙醚使溶，充分搅拌混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使均匀，得混合物料，然后将混合物料置50℃吹风干燥，使乙醚挥尽，过筛，即得。
所述的富含山核桃油中药提取物组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途或作为制备化妆品中的添加剂的用途。
Claims (5)
1.一种富含山核桃油中药提取物组合物，其特征在于，它是由以下配比原料制成：山核桃油10-50g，人参150g，当归450g，川穹100g，黄芪550g，
其制备方法如下：取人参150g，当归450g，川穹100g，黄芪550g加入药材重量比10倍浓度为75％v/v的乙醇，在38℃-40℃下浸泡168小时，滤取浸泡提取液，回收乙醇得浸提液保存备用，另将药渣分别按药材重量8倍、5倍、3倍加水煎煮提取3次，煎煮提取时间为第一次2小时，第二次1小时，第三次0.5小时，合并三次煎煮提取液，经过滤、浓缩至比重为1.0的浓缩液时，再与上述回收乙醇后的浸提液合并混匀，经干燥至含水量为4-5％，得中药提取物，另将山核桃油按重量比为1:10的比例加入到乙醚中，充分混合均匀，得山核桃油乙醚溶液，用手持喷雾器将山核桃油乙醚溶液喷雾至中药提取物中，边喷雾边搅拌使物料均匀，得混合物料，然后将混合物料置50℃吹风干燥使乙醚挥尽，即得富含山核桃油中药提取物组合物。
2.如权利要求1所述的组合物按常规工艺制成片剂、胶囊剂、颗粒剂或酒品作为制备保健品的用途。
3.如权利要求1所述的组合物作为制备化妆品中的添加剂的用途。
4.根据权利要求2所述的组合物的用途，用于配制泡腾片、咀嚼片、口含片。
5.根据权利要求2所述的组合物的用途，用于配制白酒、葡萄酒、黄酒和啤酒。
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