CN109125283A - 用于口服脱敏的花生制剂的制备 - Google Patents

用于口服脱敏的花生制剂的制备 Download PDF

Info

Publication number
CN109125283A
CN109125283A CN201811093370.9A CN201811093370A CN109125283A CN 109125283 A CN109125283 A CN 109125283A CN 201811093370 A CN201811093370 A CN 201811093370A CN 109125283 A CN109125283 A CN 109125283A
Authority
CN
China
Prior art keywords
ara
peanut
preparation
powder
allergen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811093370.9A
Other languages
English (en)
Chinese (zh)
Inventor
B·瓦尔泽
H·V·拉夫
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Societe des Produits Nestle SA
Original Assignee
Allergen Research Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=51528061&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CN109125283(A) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Allergen Research Corp filed Critical Allergen Research Corp
Publication of CN109125283A publication Critical patent/CN109125283A/zh
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61J—CONTAINERS SPECIALLY ADAPTED FOR MEDICAL OR PHARMACEUTICAL PURPOSES; DEVICES OR METHODS SPECIALLY ADAPTED FOR BRINGING PHARMACEUTICAL PRODUCTS INTO PARTICULAR PHYSICAL OR ADMINISTERING FORMS; DEVICES FOR ADMINISTERING FOOD OR MEDICINES ORALLY; BABY COMFORTERS; DEVICES FOR RECEIVING SPITTLE
    • A61J3/00—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms
    • A61J3/07—Devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms into the form of capsules or similar small containers for oral use
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4833—Encapsulating processes; Filling of capsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4875—Compounds of unknown constitution, e.g. material from plants or animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • A61K2039/541—Mucosal route
    • A61K2039/542—Mucosal route oral/gastrointestinal

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Botany (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Transplantation (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Pulmonology (AREA)
  • Medical Informatics (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Coloring Foods And Improving Nutritive Qualities (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Cosmetics (AREA)
CN201811093370.9A 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备 Pending CN109125283A (zh)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361784964P 2013-03-14 2013-03-14
US61/784,964 2013-03-14
CN201480013792.4A CN105101994B (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备

Related Parent Applications (1)

Application Number Title Priority Date Filing Date
CN201480013792.4A Division CN105101994B (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备

Publications (1)

Publication Number Publication Date
CN109125283A true CN109125283A (zh) 2019-01-04

Family

ID=51528061

Family Applications (2)

Application Number Title Priority Date Filing Date
CN201811093370.9A Pending CN109125283A (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备
CN201480013792.4A Active CN105101994B (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备

Family Applications After (1)

Application Number Title Priority Date Filing Date
CN201480013792.4A Active CN105101994B (zh) 2013-03-14 2014-03-12 用于口服脱敏的花生制剂的制备

Country Status (19)

Country Link
US (5) US9198869B2 (https=)
EP (3) EP3998080A1 (https=)
JP (3) JP6752140B2 (https=)
CN (2) CN109125283A (https=)
AU (5) AU2014240404B2 (https=)
BR (1) BR112015021756B1 (https=)
CA (1) CA2903229A1 (https=)
DK (2) DK3482771T3 (https=)
ES (2) ES2826224T3 (https=)
FI (2) FI3482771T3 (https=)
FR (1) FR23C1026I2 (https=)
HU (1) HUE051831T2 (https=)
MX (1) MX2015010315A (https=)
NL (1) NL301236I2 (https=)
NO (1) NO2023027I1 (https=)
PL (1) PL2968529T3 (https=)
PT (1) PT2968529T (https=)
SI (1) SI2968529T1 (https=)
WO (1) WO2014159607A1 (https=)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2924349B1 (fr) 2007-12-03 2010-01-01 Dbv Tech Methode de desensibilitation aux allergenes
WO2014159609A1 (en) 2013-03-14 2014-10-02 Allergen Research Corporation Peanut formulations and uses thereof
CN109125283A (zh) * 2013-03-14 2019-01-04 艾慕恩治疗公司 用于口服脱敏的花生制剂的制备
EP3185900A4 (en) 2014-08-25 2018-05-02 Aimmune Therapeutics, Inc. Egg protein formulations and methods of manufacture thereof
MA41020A (fr) 2014-11-25 2017-10-03 Evelo Biosciences Inc Compositions probiotiques et prébiotiques, et leurs procédés d'utilisation pour la modulation du microbiome
US10166286B2 (en) 2015-02-20 2019-01-01 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US10143742B2 (en) 2015-02-20 2018-12-04 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
KR20170117562A (ko) 2015-02-20 2017-10-23 더 보드 어브 트러스티스 어브 더 리랜드 스탠포드 주니어 유니버시티 혼합 알레르겐 조성물 및 그의 사용 방법
US11452774B2 (en) 2015-02-20 2022-09-27 The Board Of Trustees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
US10149904B2 (en) 2015-02-20 2018-12-11 The Board Of Trusteees Of The Leland Stanford Junior University Mixed allergen compositions and methods for using the same
TW201709926A (zh) * 2015-04-23 2017-03-16 賽諾菲公司 用於舌下投藥之吡喃葡萄糖基脂ａ及過敏原調配物
US10856567B2 (en) 2016-07-22 2020-12-08 Kari Brown Baby food products containing allergenic proteins and methods of delivering same
WO2018104691A1 (en) * 2016-12-05 2018-06-14 Reacta Biotech Limited Oral food challenge meal formulations
JP2020514306A (ja) * 2017-01-13 2020-05-21 アイミューン セラピューティクス，インコーポレイテッド 経口免疫療法用のナッツ粉および製剤の製造方法
AU2017279647B2 (en) 2017-02-15 2022-05-26 Euroimmun Medizinische Labordiagnostika Ag An improved assay for the diagnosis of peanut allergy
WO2019018529A1 (en) 2017-07-18 2019-01-24 Before Brands, Inc. METHODS OF MAKING MIXED ALLERGEN COMPOSITIONS
US11369676B2 (en) 2017-11-02 2022-06-28 Société des Produits Nestlé S.A. Methods of oral immunotherapy
GB201718342D0 (en) * 2017-11-06 2017-12-20 Cambridge Allergy Ltd Allergenic protein formulations for immunotherapy
AU2019210146A1 (en) 2018-01-16 2020-09-03 Tel Hashomer Medical Research Infrastructure And Services Ltd. Treatment and prevention of seed allergies
EP3829632A4 (en) 2018-07-27 2022-05-04 Société des Produits Nestlé S.A. SYSTEMS AND METHODS FOR DELIVERING UNIT DOSES OF ORAL IMMUNOTHERAPY
US12433945B2 (en) 2018-08-16 2025-10-07 Société des Produits Nestlé S.A. Peanut oral immunotherapy with maintenance dose
AU2019401576A1 (en) * 2018-12-17 2021-06-24 Société des Produits Nestlé S.A. Formulations for egg oral immunotherapy, methods of manufacture, and treatments for egg allergy
US12226448B2 (en) 2018-12-20 2025-02-18 Société des Produits Nestlé S.A. Peanut oral immunotherapy dosing schedule for missed doses
AU2020213085A1 (en) 2019-01-23 2021-08-12 Société des Produits Nestlé S.A. Methods for making mixed allergen compositions
CA3137295A1 (en) 2019-05-10 2020-11-19 Aimmune Therapeutics, Inc. Methods for improving the quality of life of a patient with a peanut allergy
MX2022001568A (es) * 2019-08-08 2022-03-02 Evonik Operations Gmbh Procedimiento de preparacion de una forma de dosificacion solida y un lubricante.
EP4061753A4 (en) * 2019-11-20 2023-12-13 Société des Produits Nestlé S.A. METHODS AND SYSTEMS FOR MANAGING THE DISTRIBUTION AND PROCESSING OF AN ORAL IMMUNOTHERAPY DRUG FOR FOOD ALLERGY
KR20220119076A (ko) * 2019-12-23 2022-08-26 프로타 테라퓨틱스 피티와이 엘티디 약학적 조성물
WO2022003604A1 (en) 2020-07-01 2022-01-06 Société des Produits Nestlé S. A. Determining medical staffing for oral immunotherapy
EP4274609A1 (en) 2021-01-08 2023-11-15 Regeneron Pharmaceuticals, Inc. Methods for treating peanut allergy and enhancing peanut allergen-specific immunotherapy by administering an il-4r antagonist
AU2023253754A1 (en) 2022-04-11 2024-10-17 Alk-Abelló A/S Peanut allergen composition

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101883584A (zh) * 2007-12-03 2010-11-10 Dbv技术公司 过敏原脱敏方法
CN101912364A (zh) * 2010-08-09 2010-12-15 刘会梅 银杏内酯b脂质体组合药物
WO2012123759A1 (en) * 2011-03-17 2012-09-20 Cambridge Enterprise Limited Treatment for peanut allergy

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3809767A (en) 1969-05-12 1974-05-07 Griffith Laboratories Methods of making vegetable protein concentrates
AU1589492A (en) 1991-03-01 1992-10-06 Warner-Lambert Company Starch-based controlled release compositions
US20120164306A1 (en) * 1993-08-03 2012-06-28 Girsh Leonard S Process for preparing hypoallergenic and reduced fat foods
JP3445593B2 (ja) * 1994-09-10 2003-09-08 株式会社林原生物化学研究所 ペプチドとその用途
AU2065801A (en) 1999-12-06 2001-06-12 Panacea Pharmaceuticals, Llc Passive desensitization
AU1951001A (en) * 2000-04-06 2001-09-17 Panacea Pharm Llc Microbial delivery system
EP1599185A1 (en) * 2003-02-28 2005-11-30 Alk-Abello A/S Dosage form having a saccharide matrix
EP1734975B1 (en) * 2004-03-19 2015-06-10 Herbs Spring, LLC Herbal therapy for the treatment of food allergy
BRPI0520821A2 (pt) 2005-12-28 2009-06-30 Teva Pharma formulações farmacêuticas de fenofibrato com biodisponibilidade melhorada
BRPI0921507A2 (pt) 2008-11-19 2016-01-19 Avantor Performance Mat Inc composição, método de preparação de um excipiente, comprimido farmacêutico e método de preparação do mesmo
US8399519B2 (en) 2008-12-19 2013-03-19 Merz Pharma Gmbh & Co. Kgaa 1-amino-alkylcyclohexane derivatives for the treatment of mast cell mediated diseases
US8329208B2 (en) * 2009-07-28 2012-12-11 Methylation Sciences International Srl Pharmacokinetics of S-adenosylmethionine formulations
EP2364690A1 (en) * 2010-02-12 2011-09-14 Centro De Ingenieria Genetica Y Biotecnologia Orally administrable pharmaceutical pellet of epidermal growth factor
JP5800527B2 (ja) * 2010-03-30 2015-10-28 日東電工株式会社 安定化医薬組成物、安定化医薬組成物溶液製剤、フィルム状製剤及びフィルム状製剤の製造方法
AR081776A1 (es) * 2010-06-30 2012-10-17 Novartis Ag Composiciones farmaceuticas que comprenden monohidrato de lactato de 4-amino-5-fluoro-3-[6-(4-metil-piperazin-1-il)-1h-bencimidazol-2-il]-1h-quinolin-2-ona, proceso para la produccion de la composicion
US20140207105A1 (en) * 2011-08-31 2014-07-24 Perosphere, Inc. Methods for Effectively and Rapidly Desensitizing Allergic Patients
WO2013087119A1 (en) 2011-12-16 2013-06-20 Hal Allergy Holding B.V. Pharmaceutical formulations and the use thereof for the treatment of peanut allergy
WO2014159609A1 (en) 2013-03-14 2014-10-02 Allergen Research Corporation Peanut formulations and uses thereof
CN109125283A (zh) 2013-03-14 2019-01-04 艾慕恩治疗公司 用于口服脱敏的花生制剂的制备
EP3185900A4 (en) 2014-08-25 2018-05-02 Aimmune Therapeutics, Inc. Egg protein formulations and methods of manufacture thereof
JP2020514306A (ja) 2017-01-13 2020-05-21 アイミューン セラピューティクス，インコーポレイテッド 経口免疫療法用のナッツ粉および製剤の製造方法
US11369676B2 (en) 2017-11-02 2022-06-28 Société des Produits Nestlé S.A. Methods of oral immunotherapy

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101883584A (zh) * 2007-12-03 2010-11-10 Dbv技术公司 过敏原脱敏方法
CN101912364A (zh) * 2010-08-09 2010-12-15 刘会梅 银杏内酯b脂质体组合药物
WO2012123759A1 (en) * 2011-03-17 2012-09-20 Cambridge Enterprise Limited Treatment for peanut allergy

Non-Patent Citations (3)

* Cited by examiner, † Cited by third party
Title
MARIA PELE: "Peanut allergens", 《ROMANIAN BIOTECHNOLOGICAL LETTERS》 *
S.J.KOPPELMAN: "Quantification of major peanut allergens Ara h1 and Ara h2 in the peanut varieties Runner, Spanish, Virginia, and Valencia, bred in different parts of the world", 《ALLERGY》 *
XUENI CHEN: "Ara h2 and Ara h6 have similar allergenic activity and are substantially redundant", 《INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY》 *

Also Published As

Publication number Publication date
FIC20230022I1 (fi) 2023-07-04
EP3482771B1 (en) 2023-01-18
JP6752140B2 (ja) 2020-09-09
ES2826224T3 (es) 2021-05-17
US20200129378A1 (en) 2020-04-30
PT2968529T (pt) 2020-11-10
JP2016512537A (ja) 2016-04-28
AU2016231523A1 (en) 2016-10-06
BR112015021756A8 (pt) 2019-11-19
CN105101994A (zh) 2015-11-25
BR112015021756B1 (pt) 2023-01-10
ES2940686T3 (es) 2023-05-10
US11141352B2 (en) 2021-10-12
MX2015010315A (es) 2016-04-13
HK1217660A1 (zh) 2017-01-20
AU2020202685A1 (en) 2020-05-14
AU2020202685B2 (en) 2022-01-20
US9198869B2 (en) 2015-12-01
AU2014240404B2 (en) 2016-07-21
SI2968529T1 (sl) 2021-03-31
FR23C1026I1 (fr) 2023-10-06
CN105101994B (zh) 2018-10-12
NO2023027I1 (no) 2023-07-06
DK2968529T3 (da) 2020-10-12
JP7454519B2 (ja) 2024-03-22
EP3998080A1 (en) 2022-05-18
US10449118B2 (en) 2019-10-22
EP3482771A1 (en) 2019-05-15
AU2016231523B2 (en) 2018-05-31
PL2968529T3 (pl) 2021-04-19
AU2014240404A1 (en) 2015-09-17
AU2022201858A1 (en) 2022-04-07
DK3482771T3 (da) 2023-03-20
JP6891205B2 (ja) 2021-06-18
EP2968529A4 (en) 2016-10-05
FR23C1026I2 (fr) 2024-07-26
US20180042816A1 (en) 2018-02-15
US20230120350A1 (en) 2023-04-20
US20160030289A1 (en) 2016-02-04
HUE051831T2 (hu) 2021-03-29
EP2968529A1 (en) 2016-01-20
AU2018222980A1 (en) 2018-09-20
FI3482771T3 (fi) 2023-04-03
CA2903229A1 (en) 2014-10-02
JP2019108357A (ja) 2019-07-04
JP2021073321A (ja) 2021-05-13
EP2968529B1 (en) 2020-08-05
NL301236I2 (nl) 2025-07-31
BR112015021756A2 (pt) 2017-07-18
US20140271836A1 (en) 2014-09-18
WO2014159607A1 (en) 2014-10-02
AU2022201858B2 (en) 2024-04-04

Similar Documents

Publication Publication Date Title
CN109125283A (zh) 用于口服脱敏的花生制剂的制备
AU2023202625A1 (en) Methods of manufacture of nut flours and formulations for oral immunotherapy
TWI705823B (zh) 經改良之模組化抗原運輸分子及其用途
Millard et al. 17Ricin and Related Toxins: Review and Perspective
DE102011118015A1 (de) IgY-Zusammensetzung für die Verwendung in der Zöliakie
Jutel et al. Clinical results from vaccination with recombinant grass pollen allergens
HK40003142A (en) Manufacture of peanut formulations for oral desensitization
HK40008413A (en) Manufacture of peanut formulations for oral desensitization
HK40008413B (en) Manufacture of peanut formulations for oral desensitization
Gepp Investigation of antibody responses of birch pollen allergic individuals by using chimeric allergens

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
REG Reference to a national code

Ref country code: HK

Ref legal event code: DE

Ref document number: 40003142

Country of ref document: HK

TA01 Transfer of patent application right
TA01 Transfer of patent application right

Effective date of registration: 20230105

Address after: Vevey

Applicant after: Societe des Produits Nestle S.A.

Address before: California, USA

Applicant before: AIMMUNE THERAPEUTICS, Inc.

RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20190104