CN109091599A - A kind of Chinese medicine composition and preparation method thereof for treating fracture - Google Patents
A kind of Chinese medicine composition and preparation method thereof for treating fracture Download PDFInfo
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Abstract
The present invention is suitable for technical field of traditional Chinese medicines, provide a kind of Chinese medicine composition and preparation method thereof for treating fracture, Chinese medicine composition includes the bulk pharmaceutical chemicals of following parts by weight: 30~45 parts of dried orange peel, 10~30 parts of Radix Glycyrrhizae, 30~45 parts of Radix Angelicae Sinensis, 30~60 parts of charred CORTEX EUCOMMIAE, 30~45 parts of radix achyranthis bidentatae, 15~30 parts of dandelion, 30~60 parts of Resina Draconis, 1~3 part of Moschus, 15~45 parts of pangolin, 15~20 parts of olibanum, 15~20 parts of myrrh, 30~45 parts of bush, 15~30 parts of safflower, 15~20 parts of realgar, 45~60 parts of teasel, 15~30 parts of the rhizome of davallia, 15~30 parts of Eupolyphoge sinensis, 60~70 parts of native copper, 35~40 parts of cinnabar.Whereby, the present invention can quickly eliminate the swelling of fracture early stage, accelerate the formation of fracture convalescence poroma, promote bone injury healing.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition and preparation method thereof for treating fracture.
Background technique
With the development of social market economy, the rhythm of people's life becomes to be getting faster, urban transportation and work rhythm
High speed expansion, make fracture generation rise repeatedly.Currently, the therapeutic modality that most hospitals use fracture patient is whole to be closed
Multiple or operation, closure reduction are usually to use gypsum, Boards wall, depend merely on body self-healing ability next life skeletonization after being closed reduction
Scab, the time is long, and healing is slow；Performing the operation, it is interior fixed generally to be carried out with steel plate, steel needle, and steel plate steel needle belongs to the foreign matter of body, can go out
Existing rejection, influences the formation of poroma；In addition, the detumescence for early stage of fracturing is general during closure reduction and operative treatment
It is all to take Western medicine, swelling time is long；It fractures convalescence, poroma is formed slowly, bone nonunion, and healing time is long, it is also possible to meeting
Cause some complication, for example, mental status is bad, taste are uncomfortable, hepatic and renal function is impaired etc..
CN107158188A discloses a kind of Chinese materia medica preparation of promotion fractures and bone injuries healing, selects Chinese medicine ribbed hedyotis herb, Dian Ya
Climb rattan, harms clovershrub root, climbing pothos stem and leaf, Rhizoma anemones davidii, Chinese ixora root, Herba Scleriae Terrestris, traditional Chinese herbal decoction be made, in the invention in
Medicine ingredient main function is degrading the channel, continuous muscles and bones, and there is no comprehensively treated for some complication of patient.
CN105998337A disclose a kind of Chinese medicine composition for treating fracture delayed union and its application method, in
The preparation method that ground bettle is starched in drug composition, including following raw materials: Radix Angelicae Sinensis, Rehmannia glutinosa, Radix Astragali, native copper, safflower, western party
Ginseng, dried orange peel, peach kernel, Radix Paeoniae Alba, the rhizome of davallia, Cortex Eucommiae, herba taxilli, upper limb fracture add ramulus cinnamomi, Rhizoma Et Radix Notopterygii, and fracture of lower limb adds radix cyathulae, solely
It is living, suitable ground bettle slurry is then added；The direction of invention treatment fracture is also degrading the channel, continuous muscles and bones, and fracture early stage cannot
Enough quickly detumescences, can not good complication.
In summary, the prior art there will naturally be shortcoming in practical applications, it is necessary to be improved.
Summary of the invention
In view of the above technical defects, the purpose of the present invention is to provide a kind of Chinese medicine composition for treating fracture and its preparations
Method, this method can quickly eliminate the swelling of fracture early stage, accelerate the formation of fracture convalescence poroma, promote bone injury healing.
To achieve the goals above, the present invention provides a kind of Chinese medicine composition for treating fracture, including following parts by weight
Bulk pharmaceutical chemicals: 30~45 parts of dried orange peel, 10~30 parts of Radix Glycyrrhizae, 30~45 parts of Radix Angelicae Sinensis, 30~60 parts of charred CORTEX EUCOMMIAE, 30~45 parts of radix achyranthis bidentatae,
15~30 parts of dandelion, 30~60 parts of Resina Draconis, 1~3 part of Moschus, 15~45 parts of pangolin, 15~20 parts of olibanum, myrrh 15~
20 parts, 30~45 parts of bush, 15~30 parts of safflower, 15~20 parts of realgar, 45~60 parts of teasel, 15~30 parts of the rhizome of davallia, soil
15~30 parts, 60~70 parts of native copper, 35~40 parts of cinnabar of member.
A kind of Chinese medicine composition for treating fracture according to the present invention, the bulk pharmaceutical chemicals including following parts by weight: dried orange peel 35~
42 parts, 15~25 parts of Radix Glycyrrhizae, 35~40 parts of Radix Angelicae Sinensis, 40~50 parts of charred CORTEX EUCOMMIAE, 33~40 parts of radix achyranthis bidentatae, 18~25 parts of dandelion,
40~50 parts of Resina Draconis, 1.5~2 parts of Moschus, 25~35 parts of pangolin, 17~19 parts of olibanum, 17~19 parts of myrrh, bush 36~
40 parts, 20~25 parts of safflower, 17~19 parts of realgar, 50~58 parts of teasel, 18~25 parts of the rhizome of davallia, 19~26 parts of Eupolyphoge sinensis, from
Right 64~68 parts of copper, 36~39 parts of cinnabar.
A kind of Chinese medicine composition for treating fracture according to the present invention, the bulk pharmaceutical chemicals including following parts by weight: 38 parts of dried orange peel,
22 parts of Radix Glycyrrhizae, 38 parts of Radix Angelicae Sinensis, 45 parts of charred CORTEX EUCOMMIAE, 36 parts of radix achyranthis bidentatae, 22 parts of dandelion, 45 parts of Resina Draconis, 1.8 parts of Moschus, wear mountain
30 parts of first, 18 parts of olibanum, 18 parts of myrrh, 38 parts of bush, 22 parts of safflower, 18 parts of realgar, 52 parts of teasel, 21 parts of the rhizome of davallia, soil
23 parts, 66 parts of native copper, 37 parts of cinnabar of member.
A kind of Chinese medicine composition for treating fracture according to the present invention, the present invention also provides a kind of Chinese medicine groups for treating fracture
The preparation method for closing object, includes the following steps:
Step 1 weighs
Every bulk pharmaceutical chemicals are weighed respectively according to above-mentioned parts by weight.
Step 2 preparation
The native copper forge quenching by A1, and until native copper reddens, without metallic luster, quality is crisp, then takes out, cold
But it is crushed after 30~35min, smashes it through 80~120 meshes, obtain nature copper powder.
A2 by the olibanum, myrrh respectively under the conditions of 100~120 DEG C stir-fry 5~10min, then respectively to the cream
It is put into oil suction object in fragrant, myrrh and carries out oil removing, keeps stir-frying 25~30min, takes out the olibanum, myrrh after the completion of oil removing, it is cold
But it is crushed after 15~25min, crosses 80~120 meshes, obtain frankincense powder, do not have medicinal powder.
A3 directly crushes the Resina Draconis, Moschus, realgar, cinnabar, crosses 80~120 meshes, obtains Resina Draconis powder, Moschus
Powder, realgar powder, cinnabar powder.
Remaining every bulk pharmaceutical chemicals are uniformly mixed by A4, obtain mixture.
The mixture is dried into 30~40min under the conditions of 70~80 DEG C, is then taken out, cooling 15~25min is laggard
Row crushes, and smashes it through 80~120 meshes, obtains mixture powder.
Step 3 mixing
By natural copper powder, the frankincense powder, do not have medicinal powder, Resina Draconis powder, Moschus powder, realgar powder, cinnabar powder and mixture
Powder is mixed, and obtains Chinese medicine composition after mixing.
A kind of preparation method of Chinese medicine composition for treating fracture according to the present invention, it is described to forge the method quenched are as follows: 750
The native copper is calcined into 8~15min under the conditions of~850 DEG C, is put into mature vinegar solution and quenches after having calcined, then take out,
Cooling 5~10min.
A kind of preparation method of Chinese medicine composition for treating fracture according to the present invention, the number quenched of forging is continuously to forge
It quenches 4~8 times.
A kind of preparation method of Chinese medicine composition for treating fracture according to the present invention, the total weight of the mature vinegar with from
The ratio between the total weight of right copper is 3~5:10.
A kind of preparation method of Chinese medicine composition for treating fracture according to the present invention, the oil suction object are rush, and
The water content of the rush is 2~5%.
A kind of preparation method of Chinese medicine composition for treating fracture according to the present invention, the additional amount of the rush are cream
2~2.5 times of fragrant weight.
A kind of preparation method of Chinese medicine composition for treating fracture according to the present invention, the additional amount of the rush are not
2~2.5 times of medicine weight.
The invention has the benefit that
1, degrading the channel is made with the combination of Resina Draconis, Moschus, pangolin, olibanum, myrrh, bush, safflower and realgar in the present invention
Drug is made continuous muscles and bones drug with teasel, the rhizome of davallia, Eupolyphoge sinensis and native copper combination, has continuous muscles and bones, work for fracture patient
The effect of blood stagnation resolvation, swelling and pain relieving.
2, nourishing the stomach drug, enriching yin and nourishing kidney drug and spirit quieting medicine are added in Chinese medicine composition of the invention, to the complete of patient
Body is improved, thus to because mental status is bad, taste are uncomfortable, hepatic and renal function is impaired etc. caused by fracture complication are with good
Good effect, reinvigoration promote Chinese medicine composition of the invention for the curative effect of fracture.
3, the present invention combines degrading the channel drug, continuous muscles and bones drug, nourishing the stomach drug, enriching yin and nourishing kidney drug and spirit quieting medicine and makes
It is preferable for the detumescence effect fractured early period after Chinese medicine composition, and fracture can be effectively treated, for fracturing and bone nonunion
Total effective rate is 98.7%, cure rate 93.5%, obvious effective rate 5.2%.
Detailed description of the invention
Fig. 1 is the preparation flow figure of the traditional chinese medicine composition of the invention.
Specific embodiment
In order to make the objectives, technical solutions, and advantages of the present invention clearer, below in conjunction with specific embodiment, to this
Invention is further elaborated.It should be appreciated that the specific embodiments described herein are merely illustrative of the present invention, not
For limiting the present invention.
The present invention provides a kind of Chinese medicine compositions for treating fracture, including nourishing the stomach drug, enriching yin and nourishing kidney drug, degrading the channel
Drug, continuous muscles and bones drug and spirit quieting medicine.
Nourishing the stomach drug includes the bulk pharmaceutical chemicals of following parts by weight: 30~45 parts of dried orange peel, 10~30 parts of Radix Glycyrrhizae.
Enriching yin and nourishing kidney drug includes the bulk pharmaceutical chemicals of following parts by weight: 30~45 parts of Radix Angelicae Sinensis, 30~60 parts of charred CORTEX EUCOMMIAE, and radix achyranthis bidentatae
30~45 parts, 15~30 parts of dandelion.
Degrading the channel drug includes the bulk pharmaceutical chemicals of following parts by weight: 30~60 parts of Resina Draconis, 1~3 part of Moschus, pangolin 15~
45 parts, 15~20 parts of olibanum, 15~20 parts of myrrh, 30~45 parts of bush, 15~30 parts of safflower, 15~20 parts of realgar.
Continuous muscles and bones drug includes the bulk pharmaceutical chemicals of following parts by weight: 45~60 parts of teasel, 15~30 parts of the rhizome of davallia, and Eupolyphoge sinensis 15
~30 parts, 60~70 parts of native copper.
Spirit quieting medicine includes the bulk pharmaceutical chemicals of following parts by weight: 35~40 parts of cinnabar.
Former Moschus is at high cost and low output, and therefore, the Moschus in the present invention selects muscone, Moschus in muscone
Content be 30~40%.
Raw bark of eucommia is for fracturing without therapeutic effect, and therefore, the present invention selects charred CORTEX EUCOMMIAE, and the preparation method of charred CORTEX EUCOMMIAE includes such as
Lower step: raw bark of eucommia is stir-fried under the conditions of 100~120 DEG C, and salt water is added, until raw bark of eucommia is fried；Salt is added
Water energy enough promotes the gelatinization of fiber in raw bark of eucommia, shortens the stir-frying time；The volume ratio of salt water and raw bark of eucommia is 0.4~0.6:1, and
Salt moisture 3~5 times additions, additional amount are gradually reduced.
The parts by weight of every bulk pharmaceutical chemicals in the present invention are in terms of dry weight.
Dried orange peel, warm-natured, acrid flavour, bitter；Enter the spleen channel, stomach meridian, lung channel；With regulating qi-flowing for strengthening spleen, in tune, eliminating dampness, the function of resolving sputum
Effect.Cure mainly the abdominal fullness and distention or pain, indigestion of the taste stagnation of the circulation of vital energy, abdominal distension uncomfortable in chest, anorexia and loose stool in wet turbid resistance, phlegm obstructing lung
Cough and asthma.
Radix Glycyrrhizae, taste sweet and neutral are used for the heart qi deficiency, palpitation and severe palpitation, knotted pulse and deficiency of spleen-QI and stomach-QI, fatigue and weakness etc..
Radix Angelicae Sinensis, it is warm-natured, it is sweet in flavor, pungent；Return liver, the heart, the spleen channel；With enriching blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturizing dryness and lubricating intestine then effect；
The all cards of the deficiency of blood are cured mainly, irregular menstruation, menostasis, dysmenorrhea, abdominal mass knot is poly-, and metrorrhagia and metrostaxis, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness, intestinal dryness is just
Difficulty, weight, ulcer sores, injury from falling down after dysentery with bloody stool.
Charred CORTEX EUCOMMIAE, warm-natured, sweet in flavor, micro-pungent；Enter liver and kidney channel；With nourishing liver and kidney, the effect of strengthening the bones and muscles, miscarriage prevention；With radix achyranthis bidentatae,
The enhancing of the power of nourishing liver and kidney and strengthening the bones and muscles is usually used in controlling the diseases such as the lumbocrural pain of kidney deficiency and liver and two foot inability；With teasel root, function is mended
Liver kidney, benifit waist and knees, Gu Chong appoint, and are usually used in all diseases caused by kidney deficiency and liver.
Radix achyranthis bidentatae, bitter acid, has promoting blood circulation to remove blood stasis, clearing damp diuresis, clearing heat and detoxicating effect.Cure mainly stranguria syndrome, hematuria, women
Menostasis, abdominal mass, rheumatic arthritis, tinea pedis, oedema, dysentery, malaria, diphtheria, carbuncle swells, traumatic injury.
Dandelion, bitter but sweet flavor are trembled with fear；Enter liver, stomach meridian；With clearing heat and detoxicating, the effect of diuresis dissipating bind；Cure mainly acute mammary gland
Inflammation, adenolymphitis, scrofula, boil poisonous soreness, acute conjunctivitis, cold, fever, acute tonsillitis, acute bronchitis, gastritis,
Hepatitis, cholecystitis, urinary tract infections.
Resina Draconis, it is warm-natured, flat, it is sweet in flavor, salty；Return lung, spleen, kidney three pass through；With activating microcirculation and removing stasis medicinal, swelling and pain relieving, astringing to arrest bleeding,
The remarkable efficacies such as resolving hard lump, myogenic sore.
Moschus, property is pungent, warm, bitter；Enter the heart, spleen, Liver Channel, there is the function of having one's ideas straightened out, ward off dirty, dredging collateral, scattered silt；Cure mainly apoplexy,
Coma due to blocking of the respiratory system, frightened epilepsy, middle evil unhappiness, trusted subordinate sudden and violent pain, traumatic injury, swollen ulcer drug.
Pangolin, nature and flavor are salty, cool；Channel tropism enters liver, stomach meridian；With carbuncle of bursting of reducing swelling, search that wind is active, newborn effect under promoting menstruation；
Cure mainly ulcer sore kind, wind-cold-dampness arthralgia, amenorrhea, alactation.
Olibanum, it is bitter, pungent, it is warm-natured；Enter the heart, liver, the spleen channel；With regulating qi and activating blood, analgesic therapy, the effect of chasing after poison；Cure mainly qi and blood
It stagnates, trusted subordinate's pain, ulcerative carbuncle pyogenic infections, traumatic injury, dysmenorrhea, postpartum blood stasis stabbing pain.
Myrrh, bitter is pungent, mild-natured；Enter liver, spleen, the heart, kidney channel；Cure mainly traumatic injury, metal-inflicted wound, muscles and bones, all pains of trusted subordinate, disease
Lump in the abdomen, menostasis, ulcer sore pain, anal fistula, mesh barrier.
Bush, it is sweet in flavor, salty, it puts down；Return heart, liver, the spleen channel；With promoting circulation of blood dissolving stasis, the effect of swelling and pain relieving.For menostasis pain
Through, postpartum stasis, chest and abdomen shouting pain, wound swelling and pain.
Safflower, acrid flavour are warm-natured；Enter the heart, Liver Channel；With the effect of blood circulation, stasis eliminatings relieve pain；Menostasis is cured mainly, abdominal mass is difficult
It produces, stillborn foetus, disease that postpartum lochia can't go, hemostasis are had a pain, carbuncle swells, injury from falling down.
Realgar, acrid flavour, are put down at hardship；Return heart, liver, spleen, stomach, large intestine channel；With internal heat anticance, eliminating the phlegm is relieving convulsion, desinsection treat sore,
The effect of anti-inflammatory detumescence.
Teasel, bitter, pungent, slightly warm in nature；Return liver, kidney channel；With nourishing liver and kidney, strengthening the bones and muscles, blood vessels are adjusted, only the function of metrorrhagia and metrostaxis
Effect；Cure mainly soreness of waist and knee joint, podomere flaccidity syndrome and arthralgia syndrome；Fall and flutters wound, damage muscle folding bone, movement of the foetus leakage red, metrorrhagia, spermatorrhea, leukorrhagia, ulcer sore swells.
The rhizome of davallia, bitter are warm-natured；Enter liver and kidney channel；With The strong bone of kidney tonifying, the effect of continues and hinders pain relieving.For lumbago due to the kidney deficiency,
Hiccough and deaf, tooth mobility, falling winks frustrates, injured bone；Control outward alopecia areata, leucoderma.
Eupolyphoge sinensis, taste is salty, cold in nature；Return liver warp；With broken stasis of blood blood, the effect of continuous muscles and bones.For injured bone, blood stasis closed,
Abdominal mass lump in the abdomen.
Native copper is worked hard, and is put down；With removing blood stasis and acesodyne, the effect of reunion of bone；Cure mainly traumatic injury, breaking of muscle and tendon fracture, blood stasis
Pain, accumulation, goiter, sore, scald.
Cinnabar, it is sweet in flavor, it is slightly cold；Thoughts of returning home warp；It is relieving convulsion with clearing away heart-fire, the effect of detoxifying of calming the nerves；For palpitation and being susceptible to fright, have a sleepless night more
Dream, epilepsy are gone mad, child convulsion, blurring of vision, aphtha, sore throat, and sore swollen toxin is had no peace of mind, palpitation and insomnia, infantile convulsion, epilepsy,
Sore swell and ache curative, abscess of throat, aphthae.
Fractures and bone injuries will lead to patient part channels and collaterals and be damaged, and blood overflows outside arteries and veins, hinder the local QI-blood circulation of patient, stagnation of the circulation of vital energy blood
It is tired, degrading the channel drug and continuous muscles and bones drug are contained in Chinese medicine composition of the invention, helps patient's continuous muscles and bones, activating microcirculation and removing stasis medicinal disappears
Swollen analgesic.
After patients with fractures, it is impaired to not only result in channels and collaterals, can also cause that mental status is bad, and some patientss there is also spleen
The complication such as stomach is uncomfortable, hepatic and renal function is impaired, due to Chinese medicine be particular about be whole body conditioning, Chinese medicine composition of the invention
In also contain nourishing the stomach drug dried orange peel and Radix Glycyrrhizae, patient can be helped to treat indigestion, the symptoms such as stomach dryness and thin fluid injury, there is patient
Good appetite improves the resistance of patient；Also contain enriching yin and nourishing kidney drug Radix Angelicae Sinensis, charred CORTEX EUCOMMIAE, radix achyranthis bidentatae and dandelion, helps
Patient's invigorating the spleen, is reinforced the kidney at tonifying lung, and the physical function of patient is improved, and promotes the recovery from illness of fracture；Spirit quieting medicine Zhu is gone back in Chinese medicine composition
Sand makes patient have sufficient sleep, can be carried out good rest；Therefore, Chinese medicine composition of the invention is not only to control
The fracture of patient is treated, but by the conditioning of whole body, the body of patient is consolidated, reinvigoration, to promote patients with fractures
Recovery from illness.
A kind of preparation method for the Chinese medicine composition for treating fracture of the present invention includes the following steps:
Step 1 weighs
Every bulk pharmaceutical chemicals are weighed respectively according to above-mentioned parts by weight.
Step 2 preparation
Native copper forge quenching by A1, and until native copper reddens, without metallic luster, quality is crisp, then takes out, and cooling 30
It is crushed after~35min, smashes it through 80~120 meshes, obtain nature copper powder.
Forge the method quenched are as follows: native copper is calcined into 8~15min under the conditions of 750~850 DEG C, is put into Lao Chen after having calcined
It quenches, then takes out in vinegar solution, then cooling 5~10min is continuously forged and quenched 4~8 times.
Vinegar in quenching process is not limited in that rice vinegar or other vinegar, this field skill also can be used using mature vinegar
Art personnel can select according to the actual situation.In entire calcining, quenching process, the total weight of mature vinegar and the total weight of native copper
The ratio between be 3~5:10.
Native copper mainly contains ferrous disulfide, and ferrous disulfide resolves into iron sulfide after calcining, then after being quenched with mature vinegar, table
Face generates ferrous acetate, in such manner, it is possible to keep native copper quality loose frangible, convenient for crushing, and makes iron ion in native copper more
It is easy to be precipitated, is easy to people's body absorption.
A2 due in olibanum, myrrh oil content it is high, agglomeration is easy in crushing process, therefore, the present invention is by olibanum, myrrh point
Do not stir-fry under the conditions of 100~120 DEG C 5~10min, is then put into oil suction object into olibanum, myrrh respectively and carries out oil removing, continues
Stir-fry 25~30min, and except taking out after complete oil, then cooling 15~25min is crushed, crossed 80~120 meshes, obtain olibanum
Powder does not have medicinal powder.
The present invention is verified by test of many times, after oil suction object is put into olibanum, myrrh, keeps stir-frying 25~30min, just
It can be clean by the oil removal contained in olibanum, myrrh；Certainly, if the oil suction object deoiling effect being put into is undesirable, stir-frying 25
After~30min, it is likely present some oil in olibanum, myrrh, but will not influence crushing effect.
Rush, cold nature are sweet in flavor, light；Return heart, lung, small intestine, bladder meridian；Function with promoting diuresis for stranguria, clearing heart fire
Effect；There is in rush plant thin longitudinal grin and spongioid tiny hole, the oil that olibanum can be absorbed, contained in myrrh, therefore,
Oil suction object in the present invention selects rush, can either oil removing, and have effects that clearing heart fire, improve Chinese medicine group of the present invention
Close the drug effect of object.
The water content of rush used in the present invention is 2~5%, if the water content of rush is excessively high, will affect lamp
The efficiency of core grass oil suction；The additional amount of rush is 2~2.5 times of olibanum or myrrh weight, sufficiently to remove olibanum, myrrh
In the oil that contains.
A3 due to Resina Draconis, Moschus high temperature drying or fried dry will affect its drug effect, Resina Draconis, Moschus is direct
It crushes, smashes it through 80~120 meshes, obtain Resina Draconis powder, Moschus powder.
Since realgar, the drying of cinnabar high temperature or fried dry can generate toxicity, realgar, cinnabar are directly crushed, crushed
80~120 meshes are crossed afterwards, obtain realgar powder, cinnabar powder.
A4 mixes remaining every bulk pharmaceutical chemicals, obtains mixture；
Mixture is dried into 30~40min under the conditions of 70~80 DEG C, is then taken out, carries out powder after cooling 15~25min
It is broken, 80~120 meshes are smashed it through, mixture powder is obtained.
The furnace drying method of mixture is not limited in aforesaid way, can also under the conditions of 100~120 DEG C fried dry 5~
8min, those skilled in the art can select according to the actual situation.
Step 3 mixing
By nature copper powder, frankincense powder, do not have medicinal powder, Resina Draconis powder, Moschus powder, realgar powder, cinnabar powder and mixture powder into
Row mixing, obtains Chinese medicine composition.
Certainly, Chinese medicine composition of the invention can be prepared into any suitable by those skilled in the art according to demand
Dosage form, such as tablet, capsule, granule, electuary, tincture, extract, pill, ointment etc., in order to obtain these agent
Type, those skilled in the art can carry out the pharmaceutically acceptable auxiliaries in Chinese medicine composition and pharmaceutical field of the invention conventional add
Work, pharmaceutically acceptable auxiliaries can be excipient, sweetener etc..The preparation method of the preparation of these forms is also all the routine of this field
Technological means, details are not described herein.
Chinese medicine composition of the invention in use, twice daily, ten grams every time, early, late one after each meal.
To obtain preferred forms, the present invention passes through the parts by weight formula test of secondary Chinese medicine compositions up to a hundred, and setting is such as
Under several embodiments；
Embodiment 1
Nourishing the stomach drug includes the bulk pharmaceutical chemicals of following parts by weight: 35 parts of dried orange peel, 15 parts of Radix Glycyrrhizae；
Enriching yin and nourishing kidney drug includes the bulk pharmaceutical chemicals of following parts by weight: 40 parts of Radix Angelicae Sinensis, 50 parts of charred CORTEX EUCOMMIAE, and 33 parts of radix achyranthis bidentatae, Pu
25 parts of public English；
Degrading the channel drug includes the bulk pharmaceutical chemicals of following parts by weight: 50 parts of Resina Draconis, 1.5 parts of Moschus, and 25 parts of pangolin, olibanum
19 parts, 19 parts of myrrh, 40 parts of bush, 20 parts of safflower, 17 parts of realgar；
Continuous muscles and bones drug includes the bulk pharmaceutical chemicals of following parts by weight: 58 parts of teasel, 25 parts of the rhizome of davallia, 19 parts of Eupolyphoge sinensis, natural
68 parts of copper；
The spirit quieting medicine includes the bulk pharmaceutical chemicals of following parts by weight: 36 parts of cinnabar.
Embodiment 2
Nourishing the stomach drug includes the bulk pharmaceutical chemicals of following parts by weight: 38 parts of dried orange peel, 22 parts of Radix Glycyrrhizae；
Enriching yin and nourishing kidney drug includes the bulk pharmaceutical chemicals of following parts by weight: 38 parts of Radix Angelicae Sinensis, 45 parts of charred CORTEX EUCOMMIAE, and 36 parts of radix achyranthis bidentatae, Pu
22 parts of public English；
Degrading the channel drug includes the bulk pharmaceutical chemicals of following parts by weight: 45 parts of Resina Draconis, 1.8 parts of Moschus, and 30 parts of pangolin, olibanum
18 parts, 18 parts of myrrh, 38 parts of bush, 22 parts of safflower, 18 parts of realgar；
Continuous muscles and bones drug includes the bulk pharmaceutical chemicals of following parts by weight: 52 parts of teasel, 21 parts of the rhizome of davallia, 23 parts of Eupolyphoge sinensis, natural
66 parts of copper；
Spirit quieting medicine includes the bulk pharmaceutical chemicals of following parts by weight: 37 parts of cinnabar.
Embodiment 3
Nourishing the stomach drug includes the bulk pharmaceutical chemicals of following parts by weight: 42 parts of dried orange peel, 25 parts of Radix Glycyrrhizae；
Enriching yin and nourishing kidney drug includes the bulk pharmaceutical chemicals of following parts by weight: 35 parts of Radix Angelicae Sinensis, 40 parts of charred CORTEX EUCOMMIAE, and 40 parts of radix achyranthis bidentatae, Pu
18 parts of public English；
Degrading the channel drug includes the bulk pharmaceutical chemicals of following parts by weight: 40 parts of Resina Draconis, 2 parts of Moschus, and 35 parts of pangolin, olibanum 17
Part, 17 parts of myrrh, 36 parts of bush, 25 parts of safflower, 19 parts of realgar；
Continuous muscles and bones drug includes the bulk pharmaceutical chemicals of following parts by weight: 50 parts of teasel, 18 parts of the rhizome of davallia, 26 parts of Eupolyphoge sinensis, natural
64 parts of copper；
Spirit quieting medicine includes the bulk pharmaceutical chemicals of following parts by weight: 39 parts of cinnabar.
In the present invention up to a hundred times formula tests, such as 44 parts of dried orange peel, 11 parts of Radix Glycyrrhizae, 40 parts of Radix Angelicae Sinensis, 36 parts of charred CORTEX EUCOMMIAE,
45 parts of radix achyranthis bidentatae, 16 parts of dandelion, 43 parts of Resina Draconis, 1 part of Moschus, 27 parts of pangolin, 17 parts of olibanum, 20 parts of myrrh, bush 43
Part, 25 parts of safflower, 15 parts of realgar, 50 parts of teasel, 18 parts of the rhizome of davallia, 26 parts of Eupolyphoge sinensis, 67 parts of native copper, the formulas such as 39 parts of cinnabar
Effect it is general, therefore, the implementation procedure of other embodiments is repeated no more, and choose wherein preferable ten group of formula of effect
Embodiment, the other data that part is not shown of each embodiment are shown in Table one.
The data of each embodiment of table one
To obtain best preparation method, with the parts by weight of drug component in above-described embodiment, following several preparation examples are set,
Following preparation example only lists the part different from above-mentioned steps, and identical content is no longer listed.
Preparation example 1
A2 by olibanum, myrrh respectively under the conditions of 100~120 DEG C stir-fry 5~10min, then respectively into olibanum, myrrh
It is put into oil suction object and carries out oil removing, keep stir-frying 25~30min.
Mixture is dried 30~40min by A4 under the conditions of 70~80 DEG C, is then taken out, and is carried out after cooling 15~25min
It crushes.
Preparation example 2
A2 by olibanum, myrrh respectively under the conditions of 100~120 DEG C stir-fry 5~10min, then respectively into olibanum, myrrh
It is put into oil suction object and carries out oil removing, keep stir-frying 25~30min.
Mixture is dried 30~40min by A4 under the conditions of 70~80 DEG C, is then taken out, and is carried out after cooling 15~25min
It crushes.
Preparation example 3
A2 by olibanum, myrrh respectively under the conditions of 100~120 DEG C stir-fry 5~10min, then respectively into olibanum, myrrh
It is put into oil suction object and carries out oil removing, keep stir-frying 25~30min.
Mixture is dried 30~40min by A4 under the conditions of 70~80 DEG C, is then taken out, and is carried out after cooling 15~25min
It crushes.
The implementation procedure of other preparation examples repeats no more；The other data that part is not shown of each preparation example are shown in Table two；
The data of each preparation example of table two
By repeatedly preparing test, in A2 step, olibanum, myrrh stir-frying temperature be 110 DEG C, the time that stir-fries for the first time is
8min, the stir-frying time after being put into oil suction object are 27min；In A4 step, the drying temperature of mixture is 75 DEG C, and drying time is
35min, when cooling time is 20min, Chinese medicine composition effect obtained is best.
In order to verify therapeutic effect of the invention, choose in above-described embodiment ten groups of effects are preferably formulated in being made
Medicine, and by ten kinds of application in TCM in the same age stage, identical gender, similar symptoms patient, for example, can be by ten kinds of Chinese medicines
It is respectively applied to women fracture patient of the age at 30~40 years old, or ten kinds of Chinese medicines were respectively applied to the age at 50~60 years old
Male's fracture patient, and to using patient of the invention to carry out effect return visit, as application examples, carry out clinical practice summarize and
Statistics.
Application examples 1
Zhou Wei, male, 45 years old, right hand fracture of metacarpal bone, after taking Chinese medicine prepared by the present invention, the detumescence of the right hand palm, continued in 3 days
It takes after Chinese medicine prepared by the present invention 20 days, X-ray examination discovery has a large amount of poroma to generate.
Application examples 2
Cao great Wei, male, 38 years old, knee ligament tearing, multiple fracture, after taking Chinese medicine prepared by the present invention, knee in 4 days
Joint detumescence, continues to take Chinese medicine prepared by the present invention 28 days, and X-ray examination discovery has a large amount of poroma to generate, and 39 days
Afterwards, X-ray examination, which is shown, has fully recovered.
Application examples 3
Li Jia people, male, 46 years old, fracture of rib after taking Chinese medicine prepared by the present invention, was reduced swelling in 5 days, is carried out after 13 days
X-ray examination, display have been fully recovered.
Application examples 4
Zhang Qingliang, male, 29 years old, bone nonunion more than a year took Chinese medicine prepared by the present invention after three months, and X-ray examination is aobvious
Show that fracture site has healed.
The effect of other application example is paid a return visit result and is repeated no more；The summary of application examples and statistical data are shown in Table three.
The summary and statistical data of three application examples of table
| Total case load/example | Recovery from illness number of cases/example | Effective number of cases/example | Cure rate % | Obvious effective rate % | Total effective rate % | |
| Treat Hand Fracture | 134 | 126 | 7 | 94 | 5.2 | 99.2 |
| Fractured leg | 236 | 221 | 13 | 93.6 | 5.5% | 99.1 |
| Waist fracture | 98 | 90 | 5 | 91.8 | 5.1 | 96.9 |
| Bone nonunion | 67 | 63 | 3 | 94 | 4.5 | 98.5 |
| Sum | 535 | 500 | 28 | 93.5 | 5.2 | 98.7 |
From above application examples as can be seen that Chinese medicine composition of the invention can reduce swelling for general 3~5 days in fracture early period,
Reduce swelling within one week or so compared to hospital, detumescence effect of the invention is preferable, illustrates to add in Chinese medicine composition of the invention and support
Stomach medicine object, enriching yin and nourishing kidney drug and spirit quieting medicine can effectively improve patient body function, improve the resistance of patient body, from
And reduce the time of fracture detumescence.
Found out by above-mentioned data, Chinese medicine composition of the invention can effectively control fracture, wherein the total effective rate of Treat Hand Fracture
It is 99.2%, cure rate 94%, obvious effective rate 5.2%；The total effective rate of fractured leg is 99.1%, and cure rate is
93.6%, obvious effective rate 5.5%；The total effective rate of waist fracture is 96.9%, cure rate 91.8%, obvious effective rate 5.1%；
The total effective rate of bone nonunion is 98.5%, cure rate 94%, obvious effective rate 4.5%；Chinese medicine composition of the invention is for bone
The total effective rate of folding and bone nonunion is 98.7%, cure rate 93.5%, obvious effective rate 5.2%.
Meanwhile by up to a hundred patients return visit and data statistics, there are three the Chinese medicine compositions of formula preparation to imitate for discovery
Fruit is best, is respectively as follows:
Formula one:
Nourishing the stomach drug includes the bulk pharmaceutical chemicals of following parts by weight: 35 parts of dried orange peel, 15 parts of Radix Glycyrrhizae；
Enriching yin and nourishing kidney drug includes the bulk pharmaceutical chemicals of following parts by weight: 40 parts of Radix Angelicae Sinensis, 50 parts of charred CORTEX EUCOMMIAE, and 33 parts of radix achyranthis bidentatae, Pu
25 parts of public English；
Degrading the channel drug includes the bulk pharmaceutical chemicals of following parts by weight: 50 parts of Resina Draconis, 1.5 parts of Moschus, and 25 parts of pangolin, olibanum
19 parts, 19 parts of myrrh, 40 parts of bush, 20 parts of safflower, 17 parts of realgar；
Continuous muscles and bones drug includes the bulk pharmaceutical chemicals of following parts by weight: 58 parts of teasel, 25 parts of the rhizome of davallia, 19 parts of Eupolyphoge sinensis, natural
68 parts of copper；
Spirit quieting medicine includes the bulk pharmaceutical chemicals of following parts by weight: 36 parts of cinnabar.
Formula two:
Nourishing the stomach drug includes the bulk pharmaceutical chemicals of following parts by weight: 38 parts of dried orange peel, 22 parts of Radix Glycyrrhizae；
Enriching yin and nourishing kidney drug includes the bulk pharmaceutical chemicals of following parts by weight: 38 parts of Radix Angelicae Sinensis, 45 parts of charred CORTEX EUCOMMIAE, and 36 parts of radix achyranthis bidentatae, Pu
22 parts of public English；
Degrading the channel drug includes the bulk pharmaceutical chemicals of following parts by weight: 45 parts of Resina Draconis, 1.8 parts of Moschus, and 30 parts of pangolin, olibanum
18 parts, 18 parts of myrrh, 38 parts of bush, 22 parts of safflower, 18 parts of realgar；
Continuous muscles and bones drug includes the bulk pharmaceutical chemicals of following parts by weight: 52 parts of teasel, 21 parts of the rhizome of davallia, 23 parts of Eupolyphoge sinensis, natural
66 parts of copper；
Spirit quieting medicine includes the bulk pharmaceutical chemicals of following parts by weight: 37 parts of cinnabar.
Formula three:
Nourishing the stomach drug includes the bulk pharmaceutical chemicals of following parts by weight: 42 parts of dried orange peel, 25 parts of Radix Glycyrrhizae；
The enriching yin and nourishing kidney drug includes the bulk pharmaceutical chemicals of following parts by weight: 35 parts of Radix Angelicae Sinensis, 40 parts of charred CORTEX EUCOMMIAE, and radix achyranthis bidentatae 40
Part, 18 parts of dandelion；
Degrading the channel drug includes the bulk pharmaceutical chemicals of following parts by weight: 40 parts of Resina Draconis, 2 parts of Moschus, and 35 parts of pangolin, olibanum 17
Part, 17 parts of myrrh, 36 parts of bush, 25 parts of safflower, 19 parts of realgar；
Continuous muscles and bones drug includes the bulk pharmaceutical chemicals of following parts by weight: 50 parts of teasel, 18 parts of the rhizome of davallia, 26 parts of Eupolyphoge sinensis, natural
64 parts of copper；
Spirit quieting medicine includes the bulk pharmaceutical chemicals of following parts by weight: 39 parts of cinnabar.
In conclusion invention is with Resina Draconis, Moschus, pangolin, olibanum, myrrh, bush, safflower and realgar group
Degrading the channel drug is made in conjunction, continuous muscles and bones drug is made with teasel, the rhizome of davallia, Eupolyphoge sinensis and native copper combination, for fracture patient
Have effects that continuous muscles and bones, activating microcirculation and removing stasis medicinal, swelling and pain relieving；Nourishing the stomach drug is additionally added in Chinese medicine composition of the invention, enriching yin is mended
Renal drug object and spirit quieting medicine improve the whole body of patient, thus to because mental status is bad caused by fracture, taste not
Adjust, hepatic and renal function is impaired etc., and complication have good effect, reinvigoration promotes Chinese medicine composition of the invention for bone
The curative effect of folding；The present invention is by degrading the channel drug, continuous muscles and bones drug, nourishing the stomach drug, enriching yin and nourishing kidney drug and spirit quieting medicine group
It is preferable for the detumescence effect fractured early period after Chinese medicine composition is made in conjunction, and fracture can be effectively treated, for fracturing with bone not
Total effective rate even is 98.7%, cure rate 93.5%, obvious effective rate 5.2%.
Certainly, the present invention can also have other various embodiments, without deviating from the spirit and substance of the present invention, ripe
It knows those skilled in the art and makes various corresponding changes and modifications, but these corresponding changes and change in accordance with the present invention
Shape all should fall within the scope of protection of the appended claims of the present invention.
Claims (10)
1. a kind of Chinese medicine composition for treating fracture, which is characterized in that the bulk pharmaceutical chemicals including following parts by weight: dried orange peel 30~45
Part, 10~30 parts of Radix Glycyrrhizae, 30~45 parts of Radix Angelicae Sinensis, 30~60 parts of charred CORTEX EUCOMMIAE, 30~45 parts of radix achyranthis bidentatae, 15~30 parts of dandelion, dragon
30~60 parts of dragon's blood, 1~3 part of Moschus, 15~45 parts of pangolin, 15~20 parts of olibanum, 15~20 parts of myrrh, bush 30~45
Part, it is 15~30 parts of safflower, 15~20 parts of realgar, 45~60 parts of teasel, 15~30 parts of the rhizome of davallia, 15~30 parts of Eupolyphoge sinensis, natural
60~70 parts of copper, 35~40 parts of cinnabar.
2. a kind of Chinese medicine composition for treating fracture according to claim 1, which is characterized in that including following parts by weight
Bulk pharmaceutical chemicals: 35~42 parts of dried orange peel, 15~25 parts of Radix Glycyrrhizae, 35~40 parts of Radix Angelicae Sinensis, 40~50 parts of charred CORTEX EUCOMMIAE, 33~40 parts of radix achyranthis bidentatae,
18~25 parts of dandelion, 40~50 parts of Resina Draconis, 1.5~2 parts of Moschus, 25~35 parts of pangolin, 17~19 parts of olibanum, myrrh 17
~19 parts, 36~40 parts of bush, 20~25 parts of safflower, 17~19 parts of realgar, 50~58 parts of teasel, 18~25 parts of the rhizome of davallia,
19~26 parts of Eupolyphoge sinensis, 64~68 parts of native copper, 36~39 parts of cinnabar.
3. a kind of Chinese medicine composition for treating fracture according to claim 2, which is characterized in that including following parts by weight
Bulk pharmaceutical chemicals: 38 parts of dried orange peel, 22 parts of Radix Glycyrrhizae, 38 parts of Radix Angelicae Sinensis, 45 parts of charred CORTEX EUCOMMIAE, 36 parts of radix achyranthis bidentatae, 22 parts of dandelion, Resina Draconis 45
Part, 1.8 parts of Moschus, 30 parts of pangolin, 18 parts of olibanum, 18 parts of myrrh, 38 parts of bush, 22 parts of safflower, 18 parts of realgar, teasel 52
Part, 21 parts of the rhizome of davallia, 23 parts of Eupolyphoge sinensis, 66 parts of native copper, 37 parts of cinnabar.
4. a kind of method for preparing Chinese medicine composition described in claims 1 to 3 any one, which is characterized in that including as follows
Step:
Step 1 weighs
Every bulk pharmaceutical chemicals are weighed respectively according to above-mentioned parts by weight；
Step 2 preparation
The native copper forge quenching by A1, and until native copper reddens, without metallic luster, quality is crisp, then takes out, and cooling 30
It is crushed after~35min, smashes it through 80~120 meshes, obtain nature copper powder；
A2 by the olibanum, myrrh respectively under the conditions of 100~120 DEG C stir-fry 5~10min, then respectively to the olibanum, do not have
It is put into oil suction object in medicine and carries out oil removing, keeps stir-frying 25~30min, takes out the olibanum, myrrh after the completion of oil removing, cooling 15~
It is crushed after 25min, crosses 80~120 meshes, obtain frankincense powder, do not have medicinal powder；
A3 directly crushes the Resina Draconis, Moschus, realgar, cinnabar, cross 80~120 meshes, obtain Resina Draconis powder, Moschus powder,
Realgar powder, cinnabar powder；
Remaining every bulk pharmaceutical chemicals are uniformly mixed by A4, obtain mixture；
The mixture is dried into 30~40min under the conditions of 70~80 DEG C, is then taken out, carries out powder after cooling 15~25min
It is broken, 80~120 meshes are smashed it through, mixture powder is obtained.
Step 3 mixing
By natural copper powder, the frankincense powder, do not have medicinal powder, Resina Draconis powder, Moschus powder, realgar powder, cinnabar powder and mixture powder into
Row mixing, obtains Chinese medicine composition after mixing.
5. a kind of preparation method of Chinese medicine composition for treating fracture according to claim 4, which is characterized in that described to forge
The method quenched are as follows: the native copper is calcined into 8~15min under the conditions of 750~850 DEG C, mature vinegar solution is put into after having calcined
Middle quenching, then takes out, cooling 5~10min.
6. a kind of preparation method of Chinese medicine composition for treating fracture according to claim 5, which is characterized in that described to forge
The number quenched is continuously to forge to quench 4~8 times.
7. a kind of preparation method of Chinese medicine composition for treating fracture according to claim 6, which is characterized in that described old
The ratio between total weight and the total weight of native copper of mature vinegar are 3~5:10.
8. a kind of preparation method of Chinese medicine composition for treating fracture according to claim 4, which is characterized in that the suction
Oily object is rush.
9. a kind of preparation method of Chinese medicine composition for treating fracture according to claim 8, which is characterized in that the lamp
The additional amount of core grass is 2~2.5 times of olibanum weight.
10. a kind of preparation method of Chinese medicine composition for treating fracture according to claim 8, which is characterized in that described
The additional amount of rush is 2~2.5 times of myrrh weight.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101612279A (en) * | 2009-07-31 | 2009-12-30 | 徐先启 | A kind of Chinese medicine preparation that promotes union of fracture |
| WO2017215681A1 (en) * | 2016-06-13 | 2017-12-21 | 赵吉永 | Formula for treating injuries from knocks and falls |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101612279A (en) * | 2009-07-31 | 2009-12-30 | 徐先启 | A kind of Chinese medicine preparation that promotes union of fracture |
| WO2017215681A1 (en) * | 2016-06-13 | 2017-12-21 | 赵吉永 | Formula for treating injuries from knocks and falls |
Non-Patent Citations (2)
| Title |
|---|
| 张洪魁等: "《中药研究进展》", 28 February 1990, 中国医药科技出版社 * |
| 陈秀瑷等: "《中药炮制技术》", 31 January 2017, 中国医药科技出版社 * |
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Application publication date: 20181228 |