CN109091275B - Biodegradable stent - Google Patents
Biodegradable stent Download PDFInfo
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- CN109091275B CN109091275B CN201810971039.6A CN201810971039A CN109091275B CN 109091275 B CN109091275 B CN 109091275B CN 201810971039 A CN201810971039 A CN 201810971039A CN 109091275 B CN109091275 B CN 109091275B
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- 230000002093 peripheral effect Effects 0.000 claims abstract description 21
- 230000008093 supporting effect Effects 0.000 abstract description 42
- 230000003014 reinforcing effect Effects 0.000 abstract 1
- 229910003460 diamond Inorganic materials 0.000 description 10
- 239000010432 diamond Substances 0.000 description 10
- 239000000463 material Substances 0.000 description 4
- 210000000056 organ Anatomy 0.000 description 4
- 238000003825 pressing Methods 0.000 description 4
- 206010040007 Sense of oppression Diseases 0.000 description 3
- 125000004122 cyclic group Chemical group 0.000 description 3
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- 239000000969 carrier Substances 0.000 description 1
- 230000015556 catabolic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000004891 communication Methods 0.000 description 1
- 238000002788 crimping Methods 0.000 description 1
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2210/00—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
- A61F2210/0004—Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
Abstract
The invention relates to the field of biological stents, and aims to solve the problem of insufficient radial supporting force of the existing biodegradable stent, and provide a biodegradable stent which comprises an inner-layer tube stent and an outer-layer tube stent sleeved on the periphery of the inner-layer tube stent, wherein the tube walls of the inner-layer tube stent and the outer-layer tube stent are hollow net structures; the outer peripheral wall of the inner layer pipe bracket is provided with a plurality of rows of hole groups at intervals along the circumferential direction, each row of hole groups comprises a plurality of connecting holes at intervals along the axial direction, and each connecting hole extends along the radial direction; the inner peripheral wall of the outer layer pipe support is provided with connecting columns extending along the radial direction, each connecting hole is correspondingly provided with a connecting column, and each connecting column is correspondingly embedded and connected with one connecting hole. Through setting up outer layer pipe support and inlayer pipe support, reinforcing holistic radial holding power, the setting of connecting hole and spliced pole can not weaken the radial holding power of outer layer pipe support and inlayer pipe support.
Description
Technical Field
The invention relates to the field of biological stents, in particular to a biodegradable stent.
Background
Scaffold materials are often used in surgical procedures such as vascular scaffolds, intestinal scaffolds that provide support, artificial bone scaffolds, artificial organ scaffolds, etc. that act as carriers for nutrients and provide a certain size structure. Early stent materials, which are typically metallic or some other non-degradable material, often required secondary surgical removal with some attendant negative effects; the biodegradable stent is made of a material which can be dissolved in a human body and can be absorbed by the human body after being put into the body.
The biodegradable stent can realize the recovery of vascular functions through complete degradation, reduce the occurrence rate of long-term adverse events, and simultaneously leave more selection space for diagnosis and treatment schemes possibly needed by patients in the future. The biggest problem with biodegradable stents is insufficient radial support.
Disclosure of Invention
The invention aims to provide a biodegradable stent so as to solve the problem of insufficient radial supporting force of the existing biodegradable stent.
Embodiments of the present invention are implemented as follows:
the embodiments of the present invention provide a biodegradable stent,
the inner layer pipe support and the outer layer pipe support are hollow net-shaped;
the outer peripheral wall of the inner layer pipe bracket is provided with a plurality of rows of hole groups at intervals along the circumferential direction, each row of hole groups comprises a plurality of connecting holes at intervals along the axial direction, and each connecting hole extends along the radial direction;
the inner peripheral wall of the outer layer pipe support is provided with connecting columns extending along the radial direction, each connecting hole is correspondingly provided with a connecting column, and each connecting column is correspondingly embedded and connected with one connecting hole.
The existing biodegradable support has the problem that the radial supporting force is insufficient, and compared with the existing biodegradable support, the existing biodegradable support is provided with the inner-layer tube support and the outer-layer tube support, the novel biodegradable support is low in production cost change, and the radial supporting force can be effectively improved.
The distribution of connecting hole and spliced pole on inlayer pipe support and outer pipe support helps balanced inlayer pipe support and outer pipe support everywhere the traction force between, under inlayer pipe support and outer pipe support struts and the pressure and holds two kinds of circumstances, can keep balanced steady state to guarantee that radial holding power is intact.
In one implementation of the present embodiment:
the radial length dimension of the connecting hole is smaller than that of the connecting column;
the outer peripheral wall of the inner layer pipe bracket and the inner peripheral wall of the outer layer pipe bracket are arranged at intervals.
In one implementation of the present embodiment:
the inner pipe bracket comprises a plurality of first annular units which are arranged side by side along the axial direction; each first annular unit comprises a plurality of first frames which are sequentially connected along the circumferential direction and are in a regular hexagon shape; edges of two adjacent first frames in each first annular unit are connected in a superposition mode, and the two first frames between the two adjacent first annular units are connected correspondingly and correspondingly in sharp angles;
the outer tube support comprises a plurality of second annular units which are arranged side by side along the axial direction; each second annular unit comprises a plurality of second frames which are sequentially connected along the circumferential direction and are hexagonal; the edges of two adjacent second frames in each second annular unit are connected in a superposition mode, and the two second frames between the two adjacent second annular units are connected correspondingly and correspondingly in a sharp corner mode.
In one implementation of the present embodiment:
edges of the first annular units, which are connected with each other by two adjacent first frames, are arranged along the axial direction;
the edges of the second annular units, which are connected with each other by the adjacent two second frames, are also arranged along the axial direction.
In one implementation of the present embodiment:
edges of two adjacent first frames in the first annular unit, which are connected in a superposition manner, extend along the axial direction and are circumferentially arranged along the circumferential direction;
the edges of the adjacent two second frames in the second annular unit, which are connected in a superposition manner, extend along the axial direction and are circumferentially arranged along the circumferential direction.
In one implementation of the present embodiment:
the middle part of the edge where two adjacent first frames are connected in a superposition way in the first annular unit is provided with a connecting hole;
one end of the edge, which is formed by overlapping and connecting two adjacent second frames, in the second annular unit is provided with a connecting column;
the connecting column is connected with the connecting hole, and the first annular unit and the second annular unit are staggered in the axial direction.
The beneficial effects of the invention are as follows: the biodegradable support is characterized in that the outer layer tube support and the inner layer tube support are arranged, so that the overall radial supporting force is enhanced, and the radial supporting force of the outer layer tube support and the inner layer tube support can not be weakened due to the arrangement of the connecting holes and the connecting columns.
Drawings
In order to more clearly illustrate the technical solutions of the embodiments of the present invention, the drawings that are needed in the embodiments will be briefly described below, it being understood that the following drawings only illustrate some embodiments of the present invention and therefore should not be considered as limiting the scope, and other related drawings may be obtained according to these drawings without inventive effort for a person skilled in the art.
FIG. 1 is a schematic side view of a biodegradable stent according to embodiment 1 of the present invention;
fig. 2 is a schematic structural view of the biodegradable stent according to the embodiment 1 of the present invention in an expanded state;
fig. 3 is a schematic structural view of the biodegradable stent in a compressed state according to embodiment 1 of the present invention;
fig. 4 is a schematic structural diagram of an inner layer support frame of a biodegradable stent according to embodiment 1 of the present invention;
fig. 5 is a schematic structural diagram of an outer scaffold of a biodegradable stent according to embodiment 1 of the present invention;
fig. 6 is a schematic structural view showing a second structure of the biodegradable stent according to embodiment 1 of the present invention;
fig. 7 is a schematic structural view of a second structure of the biodegradable stent according to embodiment 1 of the present invention in a compressed state;
FIG. 8 is a schematic view showing a partial structure of a first structure of the biodegradable stent according to embodiment 2 of the present invention;
FIG. 9 is a schematic view showing a partial structure of a second structure of the biodegradable stent according to embodiment 2 of the present invention;
fig. 10 is a schematic structural view showing the unfolded state of the biodegradable stent according to embodiment 2 of the present invention;
FIG. 11 is a schematic structural view showing a compressed state of the biodegradable stent according to embodiment 2 of the present invention;
FIG. 12 is a schematic side view of a biodegradable stent according to embodiment 2 of the present invention;
fig. 13 is a schematic front view of a biodegradable stent according to embodiment 3 of the present invention;
FIG. 14 is a schematic side view of a second structure of the biodegradable stent according to embodiment 3 of the present invention;
FIG. 15 is a schematic side view of a third structure of a biodegradable stent according to embodiment 3 of the present invention;
fig. 16 is a schematic front view of a third structure of the biodegradable stent according to embodiment 3 of the present invention;
fig. 17 is a schematic front view of a first structure of a biodegradable stent according to embodiment 4 of the present invention;
fig. 18 is a schematic front view of a second structure of the biodegradable stent according to embodiment 4 of the present invention;
fig. 19 is a schematic side view of the biodegradable stent according to embodiment 4 of the present invention.
Icon: 100-inner tube support; 101-a first cyclic unit; 102-a first bezel; 110-outer tube scaffold; 111-a second cyclic unit; 112-a second bezel; 120-connecting holes; 121-connecting columns; 200-tube rack; 201-supporting columns; 210-a support ring array; 211-first diamond; 212-reinforced diamond; 220-connecting ring columns; 221-second diamond; 230-connecting strips; 240-an inner layer support frame; 241-a support frame; 242-arc-shaped pieces; 243-a support hole; 300-a stent body; 301-connecting columns; 310-a cyclic unit; 311-trapezoid frame; 312-open end; 320-a ring column connection assembly; 321-connecting strips; 330-a second tier stent; 331-connecting holes; 332-support holes; 340-third layer of brackets; 341-support columns; 400-tube rack; 410-a ring structure; 412-V-shaped frame; 413-a first frame bar; 414-a second frame bar; 415—a first pointed end; 416-second pointed end; 417-a connection terminal; 420-a connection assembly; 421-connecting bars; 422-elastic strips; 430-auxiliary structure; 431-assist bar; 440-inner layer support frame; 441-a support frame; 442-arc-shaped piece; 443-supporting holes; 444-support columns.
Detailed Description
For the purpose of making the objects, technical solutions and advantages of the embodiments of the present invention more apparent, the technical solutions of the embodiments of the present invention will be clearly and completely described below with reference to the accompanying drawings in the embodiments of the present invention, and it is apparent that the described embodiments are some embodiments of the present invention, but not all embodiments of the present invention. The components of the embodiments of the present invention generally described and illustrated in the figures herein may be arranged and designed in a wide variety of different configurations.
Thus, the following detailed description of the embodiments of the invention, as presented in the figures, is not intended to limit the scope of the invention, as claimed, but is merely representative of selected embodiments of the invention. All other embodiments, which can be made by those skilled in the art based on the embodiments of the invention without making any inventive effort, are intended to be within the scope of the invention.
It should be noted that: like reference numerals and letters denote like items in the following figures, and thus once an item is defined in one figure, no further definition or explanation thereof is necessary in the following figures.
In the description of the present invention, it should be noted that, if the terms "center", "upper", "lower", "left", "right", "vertical", "horizontal", "inner", "outer", etc. indicate an azimuth or a positional relationship based on that shown in the drawings, or an azimuth or a positional relationship in which the inventive product is conventionally put in use, it is merely for convenience of describing the present invention and simplifying the description, and it is not indicated or implied that the apparatus or element referred to must have a specific azimuth, be constructed and operated in a specific azimuth, and thus should not be construed as limiting the present invention. Furthermore, the terms "first," "second," and the like in the description of the present invention, if any, are used for distinguishing between the descriptions and not necessarily for indicating or implying a relative importance.
Furthermore, the terms "horizontal," "vertical," and the like in the description of the present invention, if any, do not denote a requirement that the component be absolutely horizontal or overhang, but rather may be slightly inclined. As "horizontal" merely means that its direction is more horizontal than "vertical", and does not mean that the structure must be perfectly horizontal, but may be slightly inclined.
In the description of the present invention, it should also be noted that, unless explicitly stated and limited otherwise, the terms "disposed," "mounted," "connected," and "connected" should be interpreted broadly, and for example, "connected" may be a fixed connection, a removable connection, or an integral connection; can be mechanically or electrically connected; can be directly connected or indirectly connected through an intermediate medium, and can be communication between two elements. The specific meaning of the above terms in the present invention will be understood in specific cases by those of ordinary skill in the art.
Example 1, refer to fig. 1-7.
The biodegradable stent provided in this embodiment is a biodegradable stent,
as shown in fig. 1, the inner tube support comprises an inner tube support 100 and an outer tube support 110 sleeved on the periphery of the inner tube support 100, wherein the tube walls of the inner tube support 100 and the outer tube support 110 are hollow net structures;
the outer circumferential wall of the inner tube bracket 100 is provided with a plurality of hole groups at intervals along the circumferential direction, each hole group includes a plurality of connection holes 120 at intervals along the axial direction, each connection hole 120 extends along the radial direction;
the inner circumferential wall of the outer tube support 110 is provided with connection posts 121 extending in the radial direction, each connection hole 120 is correspondingly provided with one connection post 121, and each connection post 121 is correspondingly embedded and connected with one connection hole 120.
The existing biodegradable stent has the problem that the radial supporting force is insufficient, and compared with the existing biodegradable stent, the existing biodegradable stent is provided with the inner-layer tube stent 100 and the outer-layer tube stent 110 by arranging the inner-layer tube stent 100 and the outer-layer tube stent 110, the production cost is not greatly changed, but the radial supporting force can be effectively improved.
The distribution of the connection holes 120 and the connection posts 121 on the inner tube support 100 and the outer tube support 110 helps to balance the pulling force between the inner tube support 100 and the outer tube support 110 everywhere, and can maintain a balanced stable state in both the case of the inner tube support 100 and the outer tube support 110 being spread and being pressed to ensure that the radial supporting force is intact.
In one implementation of the present embodiment:
as shown in fig. 1, the radial length dimension of the connection hole 120 is smaller than the radial length dimension of the connection post 121;
the outer circumferential wall of the inner tube holder 100 and the inner circumferential wall of the outer tube holder 110 are disposed at an interval therebetween.
The interval sets up, on the one hand for guarantee that inlayer pipe support 100 and outer pipe support 110 have sufficient space of dodging to prop open smoothly and hold with pressing, on the other hand, avoid outer pipe support 110 oppression inlayer pipe support 100 all the time under natural state, cause inlayer pipe support 100's radial holding power impaired, thereby influence holistic holding power.
In one implementation of the present embodiment: as shown in figures 2 and 3 of the drawings,
as shown in fig. 4, the inner tube stent 100 includes a plurality of first annular units 101 arranged side by side in the axial direction; each first annular unit 101 comprises a plurality of first frames 102 which are sequentially connected along the circumferential direction and are in a regular hexagon shape; edges of two adjacent first frames 102 in each first annular unit 101 are connected in a superposition mode, and the two first frames 102 between the two adjacent first annular units 101 are connected correspondingly and correspondingly in sharp angles;
as shown in fig. 5, the outer tube support 110 includes a plurality of second annular units 111 arranged side by side in the axial direction; each second annular unit 111 includes a plurality of second frames 112 sequentially connected along the circumferential direction and having a hexagonal shape; the edges of two adjacent second frames 112 in each second annular unit 111 are connected in a superposition manner, and the two second frames 112 between the two adjacent second annular units 111 are connected in a corresponding manner and with corresponding sharp angles.
Compared with the existing biodegradable bracket which adopts an arc-shaped structure, the hexagonal first frame 102 and the hexagonal second frame 112 can improve larger radial supporting force.
In one implementation of the present embodiment:
as shown in fig. 2 and 3, edges where two adjacent first frames 102 in the first annular unit 101 are connected in a superposition manner are arranged along the axial direction; the edges of the second annular element 111, which are connected to each other by two adjacent second rims 112, are also arranged in the axial direction. And the radial supporting force of each part is ensured to be balanced.
In one implementation of the present embodiment:
as shown in fig. 6 and 7, edges of the first annular unit 101, where two adjacent first rims 102 are connected in a superposed manner, extend along the axial direction and are circumferentially arranged along the circumferential direction; the edges of the second annular unit 111, which are connected by two adjacent second rims 112, extend in the axial direction and are circumferentially arranged.
The surrounding arrangement can increase the split force in the radial direction, thereby increasing the overall radial support force.
In one implementation of the present embodiment:
as shown in fig. 2, 3, 6 and 7, a connecting hole 120 is formed in the middle of an edge where two adjacent first frames 102 in the first annular unit 101 are overlapped and connected; one end of the edge, where two adjacent second frames 112 are connected in a superposition manner, in the second annular unit 111 is provided with a connecting column 121; the connection post 121 is connected to the connection hole 120, and the first annular unit 101 and the second annular unit 111 are disposed offset from each other in the axial direction.
The staggered arrangement enhances the support of the middle portion of the first frame 102 by the second frame 112, thereby enhancing the overall support force of the first frame 102.
Example 2, refer to fig. 8-12.
The biodegradable stent provided in this embodiment is a biodegradable stent,
the device comprises a pipe bracket 200, wherein the pipe wall of the pipe bracket 200 is in a hollowed-out net structure;
the tube stand 200 includes a support ring row 210 and a connection ring row 220 sequentially spaced apart in an axial direction, and one connection ring row 220 is provided for two adjacent support ring rows 210;
the support ring row 210 includes a plurality of first diamond-shaped frames 211 distributed along the circumferential direction, wherein a pair of sharp corners are arranged towards the circumferential direction, and the sharp corners of two adjacent first diamond-shaped frames 211 are connected with each other, as shown in fig. 8 and 9, and a plurality of reinforced diamond-shaped frames 212 with equal reduction are arranged in the first diamond-shaped frames 211; as shown in fig. 8 and 9, the connecting ring column 220 includes a plurality of second diamond-shaped elements 221 distributed along the circumferential direction and in which a pair of sharp corners are arranged toward the circumferential direction, and the sharp corners of two adjacent second diamond-shaped elements 221 are connected to each other;
as shown in fig. 10 and 11, the tip angle of the first diamond 211 facing in the circumferential direction is opposite to the tip angle of the second diamond 221 facing in the axial direction; the middle of each edge of each first diamond 211 is connected to the sharp corners of the adjacent four second diamond 221 by connecting bars 230.
The support ring array 210 can ensure and strengthen the overall radial support force of the tube support 200, strengthen the arrangement of the diamond-shaped frame 212, and further strengthen the overall radial support force. While the attachment ring array 220 is used to facilitate crimping of the entire structure to reduce the diameter of the tube holder 200 so as to be able to be fed into the interior of the organ.
In one implementation of the present embodiment:
as shown in fig. 12, the tube stand 200 is provided with a plurality of inner layer support frames 240 spaced apart in the axial direction;
each inner layer supporting frame 240 comprises a diamond-shaped supporting frame 241, the center of the supporting frame 241 coincides with the axial lead of the pipe bracket 200, and four corners of the supporting frame 241 are provided with supporting holes 243; the inner circumferential wall of the tube holder 200 is provided with a support column 201 that can be correspondingly connected to the support hole 243.
The diamond-shaped supporting frame 241 plays a role in supporting the pipe bracket 200 so as to enhance the radial supporting force of the pipe bracket 200; meanwhile, when the tube support 200 is pressed and held, the inner support 240 can be smoothly compressed, so that the diameter can be reduced, and the tube support can be sent into an organ after diameter reduction.
In one implementation of the present embodiment:
as shown in fig. 12, the outer sides of the four sharp corners of the support frame 241 are provided with arc pieces 242 extending in the circumferential direction and having outer side walls capable of fitting with the inner peripheral wall of the tube holder 200; the supporting hole 243 is disposed at the arc piece 242.
The arc-shaped piece 242 is used for realizing anastomosis between the inner support 240 and the inner peripheral wall of the tube support 200, so as to increase the effective contact area between the inner support 240 and the tube support 200, reduce the supporting force corresponding to the unit area, and avoid the excessive concentration of the supporting force, so that the inner support 240 can effectively support the tube support 200.
In one implementation of the present embodiment:
as shown in fig. 12, the outer side wall of the arc piece 242 is spaced apart from the inner peripheral wall of the tube holder 200. The interval sets up, on the one hand for guarantee that inlayer support frame 240 and pipe support 200 have sufficient space of dodging to prop open smoothly and hold with pressing, on the other hand, avoid pipe support 200 oppression inlayer support frame 240 all the time under natural state, cause inlayer support frame 240's radial holding power impaired, thereby influence holistic holding power.
In one implementation of the present embodiment:
as shown in fig. 10, four connection bars 230 around each of the first diamond-shaped frames 211 extend toward the center of the first diamond-shaped frame 211 and intersect. The connection bar 230 extends to the center of the first diamond 211, which can effectively enhance the connection strength between the first diamond 211 and the second diamond 221.
Embodiment 3, refer to fig. 13 to 16.
The biodegradable stent provided in this embodiment is a biodegradable stent,
comprises a bracket main body 300 with a hollow net-shaped pipe wall;
as shown in fig. 13, the stent body 300 includes a plurality of ring units 310 and a plurality of ring-row connection assemblies 320; each ring-shaped unit 310 comprises a plurality of trapezoid frames 311 which are annularly distributed along the circumferential direction of the bracket main body 300 and are provided with opening ends 312, the opening width of each trapezoid frame 311 is gradually increased from the bottom end to the opening ends 312, the opening ends 312 of each trapezoid frame 311 are arranged towards the axial direction, the opening ends 312 of two adjacent trapezoid frames 311 in one ring-shaped unit 310 respectively face the two ends of the bracket main body 300, and the two side arms of one trapezoid frame 311 are respectively connected with the side arms of the adjacent trapezoid frame 311 in the same ring-shaped unit 310 in an overlapping manner;
the plurality of annular units 310 are arranged at intervals along the axial direction of the bracket main body 300, two adjacent annular units 310 are connected through an annular row connecting assembly 320, and the opening ends 312 of the trapezoid frames 311 between the two adjacent annular units 310 are correspondingly arranged towards each other;
each annular row connecting assembly 320 comprises a plurality of connecting bars 321 distributed annularly along the circumferential direction, two trapezoid frames 311 of which the opening ends 312 face one end of the bracket main body 300 in adjacent two annular units 310 are connected through the connecting bars 321, and the opening ends 312 of the two trapezoid frames 311 connected by the connecting bars 321 in the adjacent two annular row connecting assemblies 320 face opposite directions.
"the open end 312 of each trapezoid frame 311 is disposed toward the axial direction" means that it is open at an end toward the end of the holder main body 300. "the open ends 312 of the adjacent two trapezoidal frames 311 in one ring-shaped unit 310 face the both ends of the holder body 300, respectively" means facing opposite directions, one toward one end of the holder body 300 and the other toward the other end of the holder body 300. "the two side arms of one trapezoid frame 311 are respectively connected to the side arms of the adjacent trapezoid frame 311 in the same annular unit 310 in a superimposed manner", the directions in which the two side arms of the two trapezoid frames 311 are arranged at the positions are aligned, and the two side arms can be superimposed. "the open ends 312 of the trapezoid frames 311 between the adjacent two annular units 310 are disposed toward the respective correspondence", the open end 312 of each trapezoid frame 311 in one annular unit 310 corresponds one-to-one with the open end 312 of one trapezoid frame 311 in the adjacent annular unit 310. "open ends 312 in the adjacent two annular units 310 are both toward one end of the holder main body 300" are connected toward only one end thereof, and are unconnected toward the other end thereof; "the open ends 312 of the two trapezoid frames 311 to which the connecting bars 321 in the adjacent two annular row connecting members 320 are connected face opposite", the connecting bars 321 in one annular row connecting member 320 connect the trapezoid frame 311 with the open end 312 facing one end thereof, and the connecting bars 321 in the adjacent annular row connecting member 320 connect the trapezoid frame 311 with the open end 312 facing the other end thereof, so that it is possible to ensure that the stent body 300 has a sufficient radial supporting force while also having a compression effect.
Compared with the prior art adopting the arc shape and adopting the structure of the trapezoid frame 311, the radial supporting force is larger. The opposite orientation of the open ends 312 of the trapezoid frames 311 within each annular cell 310 ensures radial support of each annular cell 310.
In one implementation of the present embodiment:
as shown in fig. 14, the biodegradable stent further comprises a second layer of stent 330, and the stent body 300 is sleeved on the outer circumference of the second layer of stent 330;
the outer peripheral wall of the second-layer bracket 330 is provided with a plurality of connecting holes 331 at intervals, and the inner peripheral wall of the bracket main body 300 is provided with a plurality of connecting posts 301 which can be correspondingly clamped and matched with the connecting holes 331 at intervals.
The second-layer bracket 330 is provided with the connecting hole 331, the bracket main body 300 is provided with the connecting column 301, compared with the second-layer bracket 330 which is provided with the connecting column 301, the bracket main body 300 is provided with the connecting hole 331, and the supporting and limiting effects of the second-layer bracket 330 on the bracket main body 300 are reduced.
In one implementation of the present embodiment:
as shown in fig. 15 and 16, the biodegradable stent further comprises a third layer of stent 340, and the second layer of stent 330 is sleeved on the outer periphery of the third layer of stent 340;
the outer peripheral wall of the third layer of support 340 is provided with a plurality of support columns 341, and the inner peripheral wall of the second layer of support 330 is provided with a plurality of support holes 332 which can be correspondingly clamped and matched with the support columns 341 at intervals.
The radial supporting force of the holder body 300 is further enhanced by using the third-layer holder 340. The support holes 332 are formed in the second-layer support 330, the support columns 341 are respectively disposed on the support main body 300 and the third-layer support 340, and the support main body 300 and the third-layer support 340 apply a force to the inner side and the outer side of the second-layer support 330 from the second-layer support 330, so that not only can the radial overall support force be enhanced, but also the radial support force of the single second-layer support 330 can be not weakened.
In one implementation of the present embodiment:
as shown in fig. 14 and 15, the inner circumferential wall of the holder body 300 and the second-layer holder 330 are disposed at a distance, and the second-layer holder 330 and the third-layer holder 340 are disposed at a distance.
On the one hand, the support device is used for ensuring that the second-layer support 330 and the support main body 300 have enough avoiding space to be spread and held smoothly, and on the other hand, the support main body 300 is prevented from always pressing the second-layer support 330 in a natural state, so that the radial supporting force of the second-layer support 330 is damaged, and the whole supporting force is influenced.
In one implementation of the present embodiment:
as shown in fig. 14 and 15, the connection holes 331 and the connection posts 301 are distributed in an array along the circumferential direction;
the supporting columns 341 and the supporting holes 332 are distributed along the circumferential direction in an array manner, and one supporting hole 332 is correspondingly arranged between two adjacent connecting holes 331. The force of the holder body 300 and the third-layer holder 340 to the second-layer holder 330 is uniformly distributed along the circumferential surface of the second-layer holder 330.
Example 4, refer to fig. 17-19.
The biodegradable stent provided in this embodiment is a biodegradable stent,
comprises a tube bracket 400 with a hollow net-shaped tube wall;
as shown in fig. 17, the tube stand 400 includes a plurality of ring structures 410 and a plurality of connection members 420, the plurality of ring structures 410 being spaced apart along an axial direction of the tube stand 400, adjacent ring structures 410 being connected by one connection member 420;
the annular structure 410 comprises a plurality of V-shaped frames 412 annularly distributed along the circumferential direction, the V-shaped frames 412 comprise two first frame strips 413 with equal length and two second frame strips 414 with equal length, and the length dimension of the first frame strips 413 is larger than that of the second frame strips 414; one end of the two first frame strips 413 is connected to form a first sharp angle end 415, one end of the two second frame strips 414 is connected to form a second sharp angle end 416, and the remaining two ends of the two first frame strips 413 are respectively correspondingly connected with the remaining two ends of the second frame strips 414 to form two connecting ends 417; the first sharp corner 415 and the second sharp corner 416 are both disposed toward and are oriented in unison with the axial direction of the tube holder 400;
each connection assembly 420 includes a plurality of connection bars 421 and a plurality of elastic bars 422 annularly distributed along the circumferential direction and arranged at intervals, each connection bar 421 and each elastic bar 422 are arranged to extend along the axial direction of the tube holder 400, the first pointed end 415 and the second pointed end 416 of adjacent sides of the adjacent two annular structures 410 are connected by the elastic bars 422, and the connection ends 417 of the adjacent two annular structures 410 are connected by the connection bars 421.
The two first frame strips 413 and the second frame strips 414 which are arranged in a V shape are arranged to form a V-shaped frame 412, and the angles of the first frame strips 413 and the second frame strips 414 can be adjusted, but because the lengths of the first frame strips 413 and the second frame strips 414 are inconsistent, the first frame strips 413 and the second frame strips 414 are blocked by each other when compressed, and are not easy to compress, so that enough radial supporting force can be provided for the pipe bracket 400, namely, the V-shaped frame 412 has the characteristic of triangle stability. The angles of the first frame strip 413 and the second frame strip 414 can be adjusted, and the pipe bracket 400 can realize the compression and diameter reduction treatment. The provision of the elastic strip 422, on the one hand, enhances the connection between the two annular structures 410 to enhance the radial support force, and, on the other hand, ensures that the V-shaped frame 412 is smoothly compressed while enhancing the radial support force.
In one implementation of the present embodiment:
as shown in fig. 18, one side of the first pointed end 415 of each V-shaped frame 412 is provided with an auxiliary structure 430;
the auxiliary structure 430 includes two auxiliary bars 431 having equal lengths; the length of each auxiliary bar 431 is equal to that of the second frame bar 414, each auxiliary bar 431 is arranged parallel to the auxiliary bar 431, one end of each auxiliary bar 431 is connected with the first sharp corner end 415, and the other end of each auxiliary bar 431 is connected with the connecting bar 421.
The auxiliary structure 430 further enhances the radial support of the V-shaped frame 412.
In one implementation of the present embodiment:
as shown in fig. 19, the tube stand 400 is provided with a plurality of inner layer support frames 440 spaced apart in the axial direction;
each inner layer supporting frame 440 comprises a diamond-shaped supporting frame 441, the center of the supporting frame 441 coincides with the axial lead of the pipe bracket 400, and four corners of the supporting frame 441 are provided with supporting holes 443;
the inner peripheral wall of the tube holder 400 is provided with support columns 444 capable of being correspondingly connected to the support holes 443.
The diamond-shaped supporting frame 441 plays a supporting role on the tube bracket 400 to enhance the radial supporting force of the tube bracket 400; meanwhile, when the tube support 400 is pressed and held, the inner support 440 can be smoothly compressed, so that the diameter can be reduced, and the tube support can be sent into the organ after the diameter is reduced.
In one implementation of the present embodiment:
as shown in fig. 19, the outer sides of the four sharp corners of the support frame 441 are provided with arc-shaped pieces 442 extending in the circumferential direction and the outer side walls of which can be fitted to the inner peripheral wall of the tube holder 400; the support hole 443 is provided to the arc 442.
The arc-shaped member 442 is used for realizing the anastomosis between the inner support frame 440 and the inner peripheral wall of the tube support 400, so as to increase the effective contact area between the inner support frame 440 and the tube support 400, reduce the supporting force corresponding to the unit area, and avoid the excessive concentration of the supporting force, so that the inner support frame 440 can effectively support the tube support 400.
In one implementation of the present embodiment:
as shown in fig. 19, the outer side wall of the arc 442 is spaced apart from the inner peripheral wall of the tube holder 400. The interval sets up for guarantee that inlayer support frame 440 and pipe support 400 have sufficient space of dodging to prop open smoothly and hold with pressing, avoid pipe support 400 oppression inlayer support frame 440 all the time under natural state, cause inlayer support frame 440's radial holding power impaired, thereby influence holistic holding power.
The above description is only of the preferred embodiments of the present invention and is not intended to limit the present invention, but various modifications and variations can be made to the present invention by those skilled in the art. Any modification, equivalent replacement, improvement, etc. made within the spirit and principle of the present invention should be included in the protection scope of the present invention.
Claims (3)
1. A biodegradable stent, characterized in that:
the inner layer pipe support and the outer layer pipe support are hollow net-shaped structures;
the outer peripheral wall of the inner pipe bracket is provided with a plurality of rows of hole groups at intervals along the circumferential direction, each row of hole groups comprises a plurality of connecting holes at intervals along the axial direction, and each connecting hole extends along the radial direction;
the inner peripheral wall of the outer tube support is provided with connecting columns extending along the radial direction, each connecting hole is correspondingly provided with one connecting column, and each connecting column is correspondingly embedded and connected with one connecting hole;
the inner pipe bracket comprises a plurality of first annular units which are arranged side by side along the axial direction; each first annular unit comprises a plurality of first frames which are sequentially connected along the circumferential direction and are in a regular hexagon shape; edges of two adjacent first frames in each first annular unit are connected in a superposition mode, and the two adjacent first frames between the two adjacent first annular units are connected in a corresponding sharp angle mode;
the outer tube support comprises a plurality of second annular units which are arranged side by side along the axial direction; each second annular unit comprises a plurality of second frames which are sequentially connected along the circumferential direction and are hexagonal; edges of two adjacent second frames in each second annular unit are connected in a superposition mode, and the two adjacent second frames between the two adjacent second annular units are connected correspondingly and correspondingly in sharp angles;
edges of adjacent two first side frames in the first annular unit, which are connected in a superposition manner, extend along the axial direction and are circumferentially arranged along the circumferential direction;
edges, which are formed by overlapping and connecting two adjacent second frames, in the second annular unit extend along the axial direction and are circumferentially arranged along the circumferential direction; the connecting holes are formed in the middle of the edge where two adjacent first side frames are connected in a superposition mode in the first annular unit;
one end of an edge, where two adjacent second frames are connected in a superposition manner, of the second annular unit is provided with the connecting column;
the connecting column is connected with the connecting hole, and the first annular unit and the second annular unit are staggered in the axial direction.
2. The biodegradable stent of claim 1, wherein:
the radial length dimension of the connecting hole is smaller than that of the connecting column;
the outer peripheral wall of the inner layer pipe bracket and the inner peripheral wall of the outer layer pipe bracket are arranged at intervals.
3. The biodegradable stent of claim 1, wherein:
edges, where two adjacent first frames are connected in a superposition mode, of the first annular units are arranged along the axial direction;
the edges of the second annular units, which are connected with the adjacent two second frames in a superposition manner, are also arranged along the axial direction.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810971039.6A CN109091275B (en) | 2018-08-24 | 2018-08-24 | Biodegradable stent |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810971039.6A CN109091275B (en) | 2018-08-24 | 2018-08-24 | Biodegradable stent |
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| Publication Number | Publication Date |
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| CN109091275A CN109091275A (en) | 2018-12-28 |
| CN109091275B true CN109091275B (en) | 2024-01-30 |
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