JP2016221055A - Implant member and its manufacturing method - Google Patents

Abstract

PROBLEM TO BE SOLVED: To provide an implant member that can easily be formed in a three-dimensional shape along an outer surface or an inner surface of an object, can hold the three-dimensional shape after the formation against an external force received from inside a body by enhancing the rigidity after the formation, and eliminates the need for an extra member and can avoid a falling risk of the extra member essentially, and provide its manufacturing method.SOLUTION: An implant member includes multiple mesh plates 12 having multiple connection parts positioned in the polygonal vertex, and continuously formed of opening patterns 13 having multiple curved lattice bridges for connecting adjacent connection parts. The multiple mesh plates 12 are stacked by shifting the opening patterns 13, and further are connected partially. A portion of the opening patterns 13 is alternately curved and projected in the stacked direction, and is mechanically connected with the stacked opening patterns 13 of the other mesh plate 12 to maintain a three dimensional shape.SELECTED DRAWING: Figure 1

Description

  The present invention relates to an implant member to be implanted in the body and a method for manufacturing the implant member.

  An implant member is a general term for instruments that are implanted in the body. Implant members are widely used for medical purposes, and include artificial dental roots (dental implants) that are embedded in jawbones instead of lost roots, plates and screws for fixing bones in the treatment of fractures, bone defects, and the like.

  Of the implant members, one that forms a three-dimensional shape along the outer surface or inner surface of an object (for example, a jawbone) is usually composed of a mesh plate. The implant member comprised with the mesh board is disclosed by patent documents 1-5, for example.

  The “lattice for fixing bone fragments or bridging bone defects” in Patent Document 1 is a lattice made of a biocompatible material, and has a plurality of adjacent curved lattice bridges. The ends of the lattice bridges intersect the ends of the other lattice bridges at lattice points and define lattice openings suitable for receiving the fastener shafts, such as bone screws, at the lattice bridges and lattice points. The lattice bridge surrounds an opening adapted to support the head of the fastener.

  The “cranio-facial implant” of US Pat. No. 6,053,097 is a composite surgical implant, comprising (a) a top and bottom surface each comprising a layer of biocompatible material, and (b) a surgical grade comprised between the top and bottom surfaces. And (c) an attachment structure adapted to attach the implant to a desired surface. This implant can be deformed by operating by hand, and when deformed, substantially maintains the deformed shape.

  The “three-dimensionally moldable lattice structure” of Patent Document 3 includes a lattice bridge curved in an S shape and lattice points connecting the ends of the three lattice bridges. A lattice opening is defined by being surrounded by six lattice bridges and six lattice points.

  The “stent” of Patent Document 4 is a stent including a wire skeleton frame. The frame is in a first state that is a tubular shape that is expanded and has rigidity, and is in a second state that is flexible and can be folded with low stress. In the second state, the frame walls are positioned in the folded position to form a stent diameter approximately equal to the combined thickness of the frame walls engaging adjacent to each other and formed between the expanded position and the wall adjacent position. Is done. The frame in the second state has little urging to urge the frame to the first shape.

  The “stent having different mesh patterns” in Patent Document 5 is an expandable reinforcing member. A large mesh portion having a plurality of strands disposed on one side of the reinforcing member, and a small mesh portion connected to the large mesh portion. The small mesh portion has a plurality of strands that are smaller in size and larger in number than the strands of the large mesh portion.

Japanese Patent No. 3041275 Special table 2009-538686 WO2012 / 036129 Japanese National Patent Publication No. 10-500582 JP-A-11-70168

  The implant member composed of the above-described conventional mesh plate needs to form a three-dimensional shape along the outer surface or inner surface of the object. For this reason, the mesh plate constituting the implant member is a single layer and is configured to be easily deformable. However, on the other hand, it is difficult to maintain the three-dimensional shape after formation, and there is a possibility that it is easily deformed by an external force received from the body after being embedded in the body.

In addition, in order to avoid this deformation, if the mesh plates are laminated in multiple layers, an extra member (connecting member) for connecting the laminated mesh plates so that no gap is generated is required, and the connecting member may fall off. It was.
On the other hand, when the rigidity of one mesh plate is increased, deformation for forming a desired three-dimensional shape becomes difficult.

  The present invention has been developed to solve the above-described problems. That is, the object of the present invention is to easily form a three-dimensional shape along the outer surface or inner surface of an object, and to maintain the three-dimensional shape after formation against the external force received from the body by increasing the rigidity after forming. It is an object of the present invention to provide an implant member that can be used and that does not require an extra member and that can essentially avoid the possibility of dropping off the extra member, and a method for manufacturing the implant member.

According to the present invention, a plurality of mesh plates in which an opening pattern having a plurality of connecting portions located at the vertexes of a polygon and a plurality of curved lattice bridges connecting the adjacent connecting portions are continuously formed. With
A plurality of mesh plates are laminated with the opening pattern shifted, and further partially connected,
Implants characterized in that a part of the opening pattern protrudes alternately curved in the laminating direction and maintains a three-dimensional shape by mechanically coupling with a part of the opening pattern of another laminated mesh plate. A member is provided.

  At least some of the plurality of mesh plates are fixedly connected to each other.

  The plurality of mesh plates are formed into a three-dimensional shape along the outer surface or inner surface of the object.

  The mesh plate is a biocompatible metal plate or a biopolymer material.

  The polygon of the opening pattern is a triangle, a quadrangle, or a hexagon.

  The connecting portion is a circle, an ellipse, a rectangle, or an arc.

  The connecting portion has an independent opening hole.

According to the present invention, (A) an opening pattern having a plurality of connecting portions located at the vertices of a polygon and a plurality of curved lattice bridges connecting adjacent connecting portions is continuously formed. Prepare multiple mesh plates,
(B) Laminating the plurality of mesh plates by shifting the opening pattern, and further partially connecting,
(C) A part of the opening pattern is pressed in a deformable direction by pressing a deformable elastic member so as to protrude alternately, and mechanically coupled to a part of the opening pattern of another mesh plate laminated thereby. Thus, a method for manufacturing an implant member is provided, which maintains a three-dimensional shape.

  In (B), at least some of the plurality of mesh plates are fixed to each other by spot welding or ultrasonic welding.

  The plurality of mesh plates are formed into a three-dimensional shape along the outer surface or inner surface of the object and the shape is maintained.

  After forming into the three-dimensional shape, a part of the opening pattern is welded or fixed to a part of the opening pattern of another mesh plate to maintain the three-dimensional shape.

  In (A), the metal plate having biocompatibility is wire cut or etched to produce the mesh plate.

  In (A), the opening pattern is formed by injection molding, laser processing, or punching processing of a biocompatible polymer material.

  According to the configuration of the present invention, since the lattice bridge has a curved shape that connects adjacent connecting portions, each mesh plate can be easily formed into a three-dimensional shape along the outer surface or the inner surface of the object by deformation of the lattice bridge. Can be molded.

  In addition, the plurality of mesh plates are stacked while shifting the opening pattern, and further partially connected, and a part of the opening pattern protrudes alternately curved in the stacking direction, and the other mesh plates stacked Since it has a gripping part that is mechanically coupled to a part of the opening pattern and maintains a three-dimensional shape, the rigidity after molding by integrating a plurality of mesh plates by changing the ratio of the mechanical coupling part (gripping part) Can be increased.

  In particular, when embedding in the body, the rigidity can be further increased by increasing the ratio of the mechanical coupling part (gripping part) by alternately curving and projecting a part of the opening pattern in the body in the stacking direction. The three-dimensional shape after formation can be held against the external force received from.

  In addition, since a part of the opening pattern is mechanically coupled with a part of the other opening pattern to maintain a three-dimensional shape, the mechanical coupling part (gripping part) is a part of the opening pattern and is integrally formed as a mesh plate. Therefore, unnecessary members are unnecessary and the possibility of dropping off the unnecessary members can be essentially avoided.

It is 1st Embodiment figure of the implant member by this invention. FIG. 2 is a detailed view of two stacked mesh plates constituting the implant member of FIG. 1. It is 1st Embodiment figure of a mesh board. It is AA sectional drawing of FIG. It is a 2nd embodiment figure of an implant member by the present invention. It is 2nd Embodiment figure of a mesh board. It is 3rd Embodiment figure of a mesh board. It is 4th Embodiment figure of a mesh board. It is 5th Embodiment figure of a mesh board. It is 6th Embodiment figure of a mesh board. It is 7th Embodiment figure of a mesh board. It is 8th Embodiment figure of a mesh board. It is 9th Embodiment figure of a mesh board. It is a whole flowchart of the manufacturing method of the implant member by this invention.

  Hereinafter, preferred embodiments of the present invention will be described in detail with reference to the accompanying drawings. In addition, the same code | symbol is attached | subjected to the common part in each figure, and the overlapping description is abbreviate | omitted.

FIG. 1 is a diagram showing a first embodiment of an implant member 10 according to the present invention. In this example, the implant member 10 of the present invention is a stent that is inserted into a blood vessel of a human body and supports the blood vessel 1 from the inside.
In FIG. 1, (A) is a side view of the implant member 10 (stent), (B) is an AA arrow view of (A), and (C) is a state diagram in which the diameter of the stent is expanded in a blood vessel.

1A and 1B, an implant member 10 according to the present invention includes two mesh plates 12. The two mesh plates 12 are formed in a three-dimensional shape (cylindrical in this example) along the inner surface of the object (blood vessel 1 in this example).
In addition, the implant member 10 of the present invention is not limited to the two mesh plates 12 and may be composed of three or more mesh plates 12.
The three-dimensional shape is not limited to the cylindrical shape, and may be other shapes. Moreover, although the inner cylinder and outer cylinder which comprise a cylindrical shape in this example form the flat mesh board 12 in the ring shape, and the end surfaces are faced | matched, you may overlap each edge part.

As shown in FIG. 1A, an opening pattern 13 is continuously formed in the two mesh plates 12.
Further, the two mesh plates 12 are laminated with the opening pattern 13 being shifted, and are further partially connected.

As shown in FIG. 1C, this implant member 10 is inserted as a stent into a blood vessel 1 of a human body and positioned at a preset position, and then a balloon 2 is inserted inside the implant member 10 to inflate the balloon 2. Thus, the diameter of the two mesh plates 12 is expanded in the blood vessel, and the blood vessel 1 is supported from the inside.
In addition, the use of the implant member 10 is not limited to a stent, and may be used for other uses.

FIG. 2 is a detailed view of the two mesh plates 12 stacked to constitute the implant member 10 of FIG.
The direction in which the two mesh plates 12 are shifted is an arbitrary direction within the plane where the two mesh plates 12 overlap. The distance to be shifted may be less than the pitch of the same opening pattern 13 within a range where the opening patterns 13 do not match.
The two mesh plates 12 are preferably the same opening pattern 13 but may be different.

In the example of FIG. 2, the two mesh plates 12 are stacked while being shifted in the left-right direction in the drawing so that a part of the connecting portion 14 (see FIG. 3) overlaps, and further partially connected.
Furthermore, at least a part of the connecting portions 14 stacked on each other are fixed to each other at the fixing point 16. This fixing can be performed by spot welding, for example.
In addition, this invention is not limited to this structure, At least one part of the some mesh board 12 should just adhere to each other.

  By providing the fixing points 16 described above, the three-dimensional shape (three-dimensional shape) of the plurality of mesh plates 12 along the outer surface or the inner surface of the object is maintained while maintaining the stacked state and the relative displacement amount of the plurality of mesh plates 12. Shape).

  FIG. 3 is a first embodiment of the mesh plate 12. In this figure, (A) is a basic opening pattern 13, (B) is a continuous state of the opening pattern 13, and (C) is an overall view of a single mesh plate 12.

  As shown in FIG. 3A, the opening pattern 13 includes a plurality of connecting portions 14 positioned at the vertices of the polygon 11 and a plurality of curved lattice bridges 15 connecting the adjacent connecting portions 14. Hereinafter, this polygon 11 is referred to as “basic polygon 11”.

  In this example, the basic polygon 11 is a hexagon and the connecting portion 14 is a circle. The connecting portion 14 is not limited to a circle, and may be an ellipse, a rectangle, or an arc.

  In this example, the connecting portion 14 has an independent opening hole 14a. The opening hole 14a is used for passing a bone screw, for example. The opening hole 14a may not be provided.

  In this example, the lattice bridge 15 is a U-shaped curve that connects adjacent connecting portions 14, and U-shaped openings are alternately arranged inward and outward for each hexagonal side. . Note that the lattice bridge 15 is not limited to a U-shape, and may be an S-shape or another curved line.

In addition, the magnitude | size of the opening pattern 13, and the magnitude | size and width | variety of the connection part 14 and the lattice bridge 15 which comprise this are arbitrary, It is good to set according to a target object.
For example, the width of the lattice bridge 15 is 1.0, 0.8, 0.3, 0.2, or 0.1 mm.

As shown in FIGS. 3B and 3C, the mesh plate 12 is a plate in which the same opening pattern 13 is continuously formed. The mesh plate 12 is a biocompatible metal plate or a biopolymer material.
“Biocompatibility” means having in vivo acceptable characteristics.
The “metal plate having biocompatibility” is, for example, stainless steel, high nitrogen stainless steel, titanium material, or the like.
The thickness of the mesh plate 12 is arbitrary and should be constant, and is set according to the object. Note that both sides of the mesh plate 12 are preferably smooth planes.

  The mesh plate 12 described above can be manufactured by etching a metal plate having biocompatibility. For the etching process, for example, photochemical etching can be used.

  4 is a cross-sectional view taken along line AA in FIG. In this figure, (A) shows a state in which two mesh plates 12 are laminated while shifting the opening pattern 13, and (B) shows a state in which a mechanical coupling part (gripping part 13 a) is formed on a part of the opening pattern 13. Show.

  As shown in FIG. 4B, in the implant member 10 of the present invention, a part of the opening pattern 13 protrudes alternately curved in the stacking direction, and one of the opening patterns 13 of the other mesh plates 12 stacked. It has a gripping part 13a that is mechanically coupled to the part and maintains a three-dimensional shape. As shown in FIG. 4 (A), the gripping portion 13a has a part of the opening pattern 13 that presses the deformable elastic member 3 and alternately curves and protrudes in the stacking direction. The three-dimensional shape can be maintained by mechanically coupling with a part of the opening pattern 13 of the mesh plate 12.

A part of the opening pattern 13 forming the grip portion 13a is a lattice bridge 15, and it is preferable that the lattice bridges 15 of the two mesh plates 12 stacked intersect each other.
In addition, this invention is not limited to this structure, You may form the holding part 13a in places other than the lattice bridge 15. FIG.

It is preferable that a part of the opening pattern 13 forming the grip portion 13a described above is deformed to the plastic deformation range beyond the elastic deformation range of the metal plate that is the material of the mesh plate 12.
With this configuration, the deformed gripping portion 13a can be held in a deformed state.
In addition, when it exceeds the plastic deformation range, it may break. Therefore, the shape and size of the opening pattern 13 are preferably set so that the deformation (strain) of each part of the opening pattern 13 is at least smaller than the breaking strain when the object is formed into a three-dimensional shape.

FIG. 5 is a diagram showing a second embodiment of the implant member 10 according to the present invention. In this example, the implant member 10 of the present invention is a cranial implant and is formed into a three-dimensional shape along the outer surface of the skull.
The target object of the implant member 10 of the present invention is not limited to the blood vessel 1 and the skull described above, and may be other objects that require a three-dimensional shape (for example, jaw bone, bone plate, epiphyseal plate). .

  FIG. 6 is a diagram showing a second embodiment of the mesh plate 12. In this figure, (A) is a basic opening pattern 13, (B) is a continuous state of the opening pattern 13, and (C) is a view showing two mesh plates 12 and fixing points 16.

In this example, the basic polygon 11 is a triangle and the connecting portion 14 is an arc. In addition, the connection part 14 is not limited to a circular arc, A circle, an ellipse, or a rectangle may be sufficient.
In this example, the lattice bridge 15 is a U-shaped curve that connects a pair of adjacent connecting portions 14, and U-shaped openings are arranged outward on each side of the triangle. Note that the lattice bridge 15 is not limited to a U-shape, and may be an S-shape or another curved line.

As shown in FIG. 6C, in this example, the two mesh plates 12 are stacked while being shifted in the vertical direction in the figure so that a part of the lattice bridge 15 overlaps.
Further, at least a part of the lattice bridges 15 stacked on each other are fixedly connected to each other at the fixing points 16 by spot welding, for example.

With the configuration of FIG. 6C, the two mesh plates 12 can form a pseudo opening hole 14 b between the adjacent lattice bridges 15. The pseudo opening hole 14b is used for, for example, passing a bone screw. The pseudo opening hole 14b may not be provided.
Other configurations are the same as those in FIG.

FIG. 7 is a diagram showing a third embodiment of the mesh plate 12. As in FIG. 6, the basic polygon 11 is a triangular opening pattern 13 and the line width is 1.0 mm in this example.
In this figure, (A) shows the same orientation of basic polygons 11 (triangles) of two mesh plates 12, and (B) shows the opposite directions.
Other configurations are the same as those in FIG.

FIG. 8 is a diagram showing a fourth embodiment of the mesh plate 12. In this figure, as in FIG. 7B, the basic polygon 11 is a triangle and the direction of the triangle is reversed.
In this figure, (A) has a line width of 0.2 mm, and (B) has a line width of 0.3 mm. The rigidity of the mesh plate 12 can be adjusted by the difference in line width.
Other configurations are the same as those in FIG.

  FIG. 9 is a diagram showing a fifth embodiment of the mesh plate 12. In this figure, (A) is a basic opening pattern 13, (B) is a continuous state of the opening pattern 13, and (C) is a view showing two mesh plates 12 and fixing points 16.

In this example, the basic polygon 11 is a rectangle, and the connecting portion 14 is a rectangle. In addition, the connection part 14 is not limited to a rectangle, A circle, an ellipse, or a circular arc may be sufficient.
The lattice bridge 15 is an S-shaped curve that connects a pair of adjacent connecting portions 14 in this example.
In this example, an independent opening 14a (see FIG. 3) may be provided in the connecting portion 14.

As shown in FIG. 9C, in this example, the two mesh plates 12 are stacked while being shifted in the vertical direction in the drawing so that the connecting portion 14 and the lattice bridge 15 partially overlap each other.
Furthermore, at least a part of the connecting portion 14 and the lattice bridge 15 that are stacked on each other are fixed to each other at a fixing point 16 by, for example, spot welding.
Other configurations are the same as those in FIG.

FIG. 10 is a diagram of a sixth embodiment of the mesh plate 12. In this figure, as in FIG. 9, the basic polygon 11 is a square opening pattern 13, and the line width is 0.8 mm in this example.
In this figure, (A) has the same orientation of the basic polygons 11 (quadrangles) of the two mesh plates 12, and (B) has the opposite directions.
Other configurations are the same as those in FIG.

FIG. 11 is a diagram of a seventh embodiment of the mesh plate 12. In this figure, as in FIG. 10A, the basic polygon 11 is a square opening pattern 13, and the directions of the basic polygon 11 (rectangle) of the two mesh plates 12 are the same.
In this figure, (A) has a line width of 0.2 mm, and (B) has a line width of 0.3 mm.
Other configurations are the same as those in FIG.

FIG. 12 is an eighth embodiment of the mesh plate 12. In this figure, (A) is a single mesh plate 12, and (B) is a diagram showing two mesh plates 12 and fixing points 16.
In this example, the basic polygon 11 is a quadrangle, and the lattice bridge 15 is S-shaped. The connecting portion 14 has a rectangular shape in which the lattice bridges 15 intersect.
Other configurations are the same as those in FIG.

FIG. 13 is a ninth embodiment of the mesh plate 12. In this figure, (A) is a single mesh plate 12, and (B) is a diagram showing two mesh plates 12 and fixing points 16.
In this example, the basic polygon 11 is a quadrangle, and the lattice bridge 15 is a straight line. The connecting portion 14 has a rectangular shape in which the lattice bridges 15 intersect.
Other configurations are the same as those in FIG.

  FIG. 14 is an overall flowchart of the method for manufacturing the implant member 10 according to the present invention. In this figure, the method of the present invention comprises steps S1 to S4.

  In step S1, a plurality of mesh plates 12 on which the same opening pattern 13 is continuously formed are prepared. That is, the mesh plate 12 is manufactured by wire cutting or etching a metal plate having biocompatibility. Alternatively, an opening pattern is formed by injection molding, laser processing, or punching processing of a biocompatible polymer material.

  In step S2, a plurality of mesh plates 12 are stacked while shifting the opening pattern 13, and further partially connected. At this time, at least some of the plurality of mesh plates 12 are fixed to each other by spot welding or ultrasonic welding.

  In step S3, the plurality of mesh plates 12 are formed into a three-dimensional shape along the outer surface or inner surface of the object, and the shapes are maintained.

  In step S4, a part of the opening pattern 13 is pressed against the deformable elastic member 3 and alternately curved and protrudes to the other side, thereby causing a part of the opening pattern 13 of the other mesh plates 12 stacked. A gripping portion 13a that is mechanically coupled to maintain a three-dimensional shape is formed.

  The implant member 10 can be manufactured by sequentially performing the above-described steps S1 to S4.

  Moreover, it is preferable to hold | maintain a three-dimensional shape by welding or adhering a part of opening pattern 13 to a part of opening pattern 13 of the other mesh board 12 after shape | molding in a three-dimensional shape.

  When the implant member 10 is a stent, for example, as shown in FIG. 1 (C), the implant member 10 is inserted into the blood vessel 1 and positioned at a preset position, and then the balloon 2 is placed inside the implant member 10. The balloon 2 is inserted to expand the diameter of the two mesh plates 12 in the blood vessel, and the blood vessel 1 is supported from the inside.

At the time of the diameter expansion, the two mesh plates 12 are sandwiched between the blood vessel 1 and the balloon 2 and compressed from both, and a part of the opening pattern 13 is deformed and mechanically coupled in the same manner as in step S4 described above. Part (gripping part 13a) is formed.
Therefore, in this case, due to the diameter expansion of the stent, the rigidity of the two mesh plates 12 is further increased, and even after the balloon 2 is removed, the three-dimensional shape after formation is resisted against the external force received from the blood vessel 1. Can be held.

  According to the configuration of the present invention described above, since the lattice bridge 15 has a curved shape that connects the adjacent connecting portions 14, each lattice bridge 15 is deformed into a three-dimensional shape along the outer surface or the inner surface of the object. The mesh plate 12 can be easily formed.

  Further, the plurality of mesh plates 12 are laminated with the opening pattern 13 being shifted and further partially connected, and a part of the opening pattern 13 protrudes alternately curved in the laminating direction, Since it has a gripping portion 13a that mechanically couples with a part of the opening pattern 13 of the mesh plate 12 and maintains a three-dimensional shape, the mesh plate 12 can be changed by changing the ratio of the mechanical coupling portion (gripping portion 13a). It can be integrated to increase the rigidity after molding.

  In particular, when being embedded in the body, a portion of the opening pattern 13 is curved and protrudes in the stacking direction in the body to increase the ratio of the mechanical coupling portion (gripping portion 13a), thereby further increasing the rigidity. The three-dimensional shape after formation can be held against the external force received from.

  In addition, since a part of the opening pattern 13 grips a part of the other opening pattern 13, the mechanical coupling part (gripping part 13 a) is a part of the opening pattern 13 and is integrally formed as the mesh plate 12. The extra member is unnecessary and the possibility of dropping off the extra member can be essentially avoided.

  In addition, this invention is not limited to embodiment mentioned above, is shown by description of a claim, and also includes all the changes within the meaning and range equivalent to description of a claim.

1 blood vessel, 2 balloon, 3 elastic member,
10 implant members, 11 basic polygons,
12 mesh plate, 13 opening pattern, 13a mechanical coupling part (gripping part),
14 connecting part, 14a opening hole, 14b pseudo opening hole,
15 lattice bridges, 16 anchor points

Claims (13)

Comprising a plurality of mesh plates in which an opening pattern having a plurality of connecting portions located at the vertices of a polygon and a plurality of curved lattice bridges connecting adjacent connecting portions is continuously formed;
A plurality of mesh plates are laminated with the opening pattern shifted, and further partially connected,
Implants characterized in that a part of the opening pattern protrudes alternately curved in the laminating direction and maintains a three-dimensional shape by mechanically coupling with a part of the opening pattern of another laminated mesh plate. Element.   The implant member according to claim 1, wherein at least some of the plurality of mesh plates are fixedly connected to each other.   The implant member according to claim 1, wherein the plurality of mesh plates are formed into a three-dimensional shape along an outer surface or an inner surface of an object.   The implant member according to claim 1, wherein the mesh plate is a biocompatible metal plate or a biopolymer material.   The implant member according to claim 1, wherein the polygon of the opening pattern is a triangle, a quadrangle, or a hexagon.   The implant member according to claim 1, wherein the connecting portion is circular, elliptical, rectangular, or arc.   The implant member according to claim 1, wherein the connecting portion has an independent opening hole. (A) preparing a plurality of mesh plates in which an opening pattern having a plurality of connecting portions located at the vertices of a polygon and a plurality of curved lattice bridges connecting adjacent connecting portions is continuously formed; ,
(B) Laminating the plurality of mesh plates by shifting the opening pattern, and further partially connecting,
(C) A part of the opening pattern is pressed in a deformable direction by pressing a deformable elastic member so as to protrude alternately, and mechanically coupled to a part of the opening pattern of another mesh plate laminated thereby. And maintaining the three-dimensional shape.   The method for manufacturing an implant member according to claim 8, wherein in (B), at least a part of the plurality of mesh plates is fixed to each other by spot welding or ultrasonic welding.   The method of manufacturing an implant member according to claim 8, wherein the plurality of mesh plates are formed into a three-dimensional shape along an outer surface or an inner surface of an object and the shape is maintained.   11. The three-dimensional shape is maintained by welding or fixing a part of the opening pattern to a part of the opening pattern of another mesh plate after forming the three-dimensional shape. A method for producing an implant member.   The method for manufacturing an implant member according to claim 8, wherein in (A), the metal plate having biocompatibility is wire cut or etched to manufacture the mesh plate. The method for manufacturing an implant member according to claim 8, wherein in (A), the opening pattern is formed by injection molding, laser processing, or punching processing of a biocompatible polymer material.