CN109090342A - Fermented tcm additive and preparation method thereof and application method - Google Patents
Fermented tcm additive and preparation method thereof and application method Download PDFInfo
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- CN109090342A CN109090342A CN201810997547.1A CN201810997547A CN109090342A CN 109090342 A CN109090342 A CN 109090342A CN 201810997547 A CN201810997547 A CN 201810997547A CN 109090342 A CN109090342 A CN 109090342A
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- motherwort
- tunning
- herba lycopi
- nutrient powder
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/12—Animal feeding-stuffs obtained by microbiological or biochemical processes by fermentation of natural products, e.g. of vegetable material, animal waste material or biomass
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01K—ANIMAL HUSBANDRY; CARE OF BIRDS, FISHES, INSECTS; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K67/00—Rearing or breeding animals, not otherwise provided for; New breeds of animals
- A01K67/02—Breeding vertebrates
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/142—Amino acids; Derivatives thereof
- A23K20/147—Polymeric derivatives, e.g. peptides or proteins
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/10—Organic substances
- A23K20/163—Sugars; Polysaccharides
Abstract
The present invention provides a kind of fermented tcm additive and preparation method thereof and application methods, are related to technical field of biological fermentation.Fermented tcm additive, including motherwort tunning and Herba Lycopi tunning；Preferably, the raw material of the motherwort fermentation includes motherwort, the raw material of the Herba Lycopi fermentation includes Herba Lycopi, and the weight ratio of the motherwort and Herba Lycopi is (15-48): (22-47), further preferably (15-45): (25-45).Fermented tcm additive provided by the invention is using motherwort tunning and Herba Lycopi tunning as main component, include a variety of active ingredients such as amino acid, polysaccharide and vitamin in motherwort tunning and Herba Lycopi tunning, mutual coordinated between various active constituents, have the function of to jenny postpartum health care, newborn cub disease incidence is reduced, the year rate of return on investment of animal-breeding is improved.
Description
Technical field
The present invention relates to technical field of biological fermentation, more particularly, to a kind of fermented tcm additive and preparation method thereof and
Application method.
Background technique
In animal-breeding production, the postpartum health care of jenny, which is all that one of puzzlement culturist is common all the time, is asked
Topic.Veterinary clinic is usually that health care is carried out by way of injecting drug, this mode, one side large labor intensity, and technology is wanted
Ask high, the common culturist for not received professional training implements extremely difficult；On the other hand, this administration mode is also animal
The factor for generating stress reaction inevitably causes jenny to generate a degree of stress reaction, to make health care
Effect is had a greatly reduced quality, or even is run counter to desire.However, jenny puerperal asthenia, has a low resistance, postpartum infection is often occurred, and is produced
Health care has to do afterwards.At the same time, weaning brash often occurs after wean for newborn cub, and postweaning multisystem failure is comprehensive
The diseases such as sign, seriously affect the survival and growth of cub.The diseases such as postweaning multisystem exhaustion syndrome (PMWS) are viral
Disease, the drug for being presently available for preventing and treating such disease is very limited, and a large amount of cub death is caused to be eliminated.The above jenny and
The aspect of cub two there are the problem of all seriously reduce the year rate of return on investment of animal-breeding.In order to improve animal-breeding
Year rate of return on investment, needs to solve the problem of above-mentioned two aspect, preferably with an energy " double gain " and application
Simply, effective product.
In view of this, the present invention is specifically proposed.
Summary of the invention
An object of the present disclosure is to provide a kind of fermented tcm additive, dynamic to alleviate male and female existing in the prior art
Health-care effect is bad after produce, and disease incidence is high after the wean of newborn cub, the technologies such as cause the year rate of return on investment of animal-breeding low
Problem.
Fermented tcm additive provided by the invention, including motherwort tunning and Herba Lycopi tunning；
Preferably, the raw material of the motherwort fermentation includes motherwort, and the raw material of the Herba Lycopi fermentation includes Herba Lycopi, described
The weight ratio of motherwort and Herba Lycopi is (15-48): (22-47), further preferably (15-45): (25-45).Further, institute
Motherwort tunning is stated mainly to be prepared from the following raw materials: 15-48 parts of motherwort, 8-12 parts of the first starch nutrient powder,
1-5 parts and koji 1-5 parts of red yeast rice；
And/or the Herba Lycopi tunning is mainly prepared from the following raw materials: 22-47 parts of Herba Lycopi, protein-based nutrition
8-12 parts of powder, 3-7 parts of the second starch nutrient powder and 1-5 parts of koji.
Further, the motherwort tunning is mainly prepared from the following raw materials: 15-35 parts of motherwort, first
8-11 parts of starch nutrient powder, 1-4 parts of red yeast rice and 1-4 parts of koji；
And/or the Herba Lycopi tunning is mainly prepared from the following raw materials: 22-45 parts of Herba Lycopi, protein-based nutrition
8-11 parts of powder, 3-6 parts of the second starch nutrient powder and 1-4 parts of koji.
Further, the motherwort tunning is mainly prepared from the following raw materials: 19-35 parts of motherwort, first
9-11 parts of starch nutrient powder, 2-4 parts of red yeast rice and 2-4 parts of koji；
And/or the Herba Lycopi tunning is mainly prepared from the following raw materials: 33-45 parts of Herba Lycopi, protein-based nutrition
9-11 parts of powder, 4-6 parts of the second starch nutrient powder and 2-4 parts of koji.
Further, the first starch nutrient powder include corn, wheat, buckwheat, rice, glutinous rice, sorghum, glutinous millet,
At least one of sweet potato, potato, Chinese yam, taro or cassava, preferably glutinous rice；
And/or the second starch nutrient powder includes corn flour, flour, buckwheat, rice meal, glutinous rice flour, sorghum
At least one of powder, glutinous millet powder, sweet potato flour, dehydrated potato powder, yam flour, taro meal or tapioca starch, preferably flour；
And/or the protein-based nutrient powder includes at least one in semen viciae fabae, pea, mung bean, red bean, kidney bean or soya bean
Kind, preferably soya bean.
The present invention second is designed to provide a kind of preparation method of fermented tcm additive, the hair which obtains
Ferment Chinese medicine additive palatability and effect are good, and preparation process is simple, easily grasps, is economical and practical, can be produced with large-scale development.
The method of fermented tcm additive provided by the invention includes the following steps: motherwort tunning and Herba Lycopi
Tunning mixing.
Further, include the following steps:
(a) the first starch nutrient powder is mixed with red yeast rice, is fermented, then mixed with motherwort and koji, fermentation obtains
Motherwort tunning；
(b) protein-based nutrient powder is mixed with the second starch nutrient powder, is fermented, then mixed with Herba Lycopi and koji,
Fermentation obtains Herba Lycopi tunning；
(c) the motherwort tunning that the step (a) obtains and the Herba Lycopi tunning that the step (b) obtains is mixed
It closes to get fermented tcm additive.
Further, the partial size of the motherwort is 200-300 mesh, preferably 250-300 mesh；
And/or the partial size of the Herba Lycopi is 200-300 mesh, preferably 250-300 mesh.
Further, in the step (a), the fermentation temperature of the first starch nutrient powder and red yeast rice is 25-33 DEG C,
Preferably 25-30 DEG C, and/or, the fermentation time is 25-35, preferably 30-35；
And/or in the step (a), the fermentation time of the motherwort is 8-12, preferably 8-10；
And/or in the step (b), the fermentation temperature of the protein-based nutrient powder and the second starch nutrient powder is
15-25 DEG C, preferably 18-25 DEG C, and/or, the fermentation time is 1-3, preferably 2-3；
And/or in the step (b), the fermentation time of the Herba Lycopi is 8-12, preferably 8-10；
Dry after the mixing and/or in the step (c), the drying temperature is 45-55 DEG C, preferably 50-55
℃。
The third object of the present invention is to provide a kind of application method of fermented tcm additive, the application method is simple,
Easy to operate, either individually feeding has preferable palatability still with animal feed mixed feeding, protects to female animals postpartum
Disease incidence has positive effect after the newborn cub wean of strong and reduction.
The application method of fermented tcm additive provided by the invention includes the following steps: to add above-mentioned fermented tcm
Independent feeding animals of fermented tcm additive that agent or above-mentioned preparation method are prepared are added to mixing in animal feed and feed
Support animal；
Preferably, the fermented tcm additive according to animal day feeding amount of dry matter the independent feeding animals of 0.5-2%；
Or the fermented tcm additive of 0.5-2% is added to mixed feeding animal in animal feed.
The present invention has the advantages that compared with the existing technology
Fermented tcm additive provided by the invention is using motherwort tunning and Herba Lycopi tunning as main component, benefit
Comprising a variety of active ingredients such as amino acid, polysaccharide and vitamin in Brittle Falsepimpernel Herb tunning and Herba Lycopi tunning, various activity at
/ mutual coordinated has the function of to reduce newborn cub disease incidence to jenny postpartum health care, improve animal-breeding
Year rate of return on investment.
The preparation method of fermented tcm additive provided by the invention is simple, easily grasps, is economical and practical, can open on a large scale
It produces.
The application method of fermented tcm additive provided by the invention is simple, easy to operate, either individually feeding or with
Animal feed mixed feeding has preferable palatability, falls ill to female animals postpartum health care and after reducing newborn cub wean
Rate has positive effect.
Specific embodiment
Embodiment of the present invention is described in detail below in conjunction with embodiment, but those skilled in the art will
Understand, the following example is merely to illustrate the present invention, and is not construed as limiting the scope of the invention.It is not specified in embodiment specific
Condition person carries out according to conventional conditions or manufacturer's recommended conditions.Reagents or instruments used without specified manufacturer is
The conventional products that can be obtained by commercially available purchase.
According to the first aspect of the invention, the present invention provides a kind of fermented tcm additives, including motherwort to ferment
Product and Herba Lycopi tunning.
Motherwort tunning and Herba Lycopi tunning are made by motherwort and the fermented technique of Herba Lycopi respectively.Motherwort and
Containing a large amount of cellulose and polysaccharide etc. in Herba Lycopi, the polysaccharide being degraded by microorganisms in fermentation process as polysaccharide or even lower level has
Conducive to active constituent release, meanwhile, microbes generate the metabolism such as a large amount of amino acid, polysaccharide and vitamin and produce in fermentation process
Object, the above various components all have activity, interact, influence each other between each component, have positive guarantor to animal body
Strong effect.
Fermented tcm additive provided by the invention is using motherwort tunning and Herba Lycopi tunning as main component, benefit
Comprising a variety of active ingredients such as amino acid, polysaccharide and vitamin in Brittle Falsepimpernel Herb tunning and Herba Lycopi tunning, various activity at
/ mutual coordinated has the function of to reduce newborn cub disease incidence to jenny postpartum health care, improve animal-breeding
Year rate of return on investment.
In one preferred embodiment, the raw material of the motherwort fermentation includes motherwort, the Herba Lycopi fermentation
Raw material includes Herba Lycopi, and the weight ratio of the motherwort and Herba Lycopi is (15-48): (22-47), further preferably (15-45):
(25-45)。
Active constituent in fermented tcm additive is mainly derived from motherwort and Herba Lycopi in raw material, motherwort and Herba Lycopi
Proportion decide the proportion of active constituent, influence the coordinated between active constituent.The proportion of motherwort and Herba Lycopi is excessive
Or it is too small, synergistic effect cannot be generated between active constituent, or even antagonism can be generated.
Wherein, the weight ratio of the raw material Herba Lycopi of the raw material motherwort and Herba Lycopi tunning of motherwort tunning such as may be used
Think, but is not limited to 15:22,15:47,48:22,48:47,15:25,15:45 or 45:45.
In one preferred embodiment, the motherwort tunning is mainly prepared from the following raw materials: benefit is female
15-48 parts careless, 8-12 parts of the first starch nutrient powder, 1-5 parts of red yeast rice and 1-5 parts of koji.
Motherwort bitter, pungent, cold nature；Return liver, pericardium, bladder meridian；With promoting blood circulation for regulating menstruation, inducing diuresis to remove edema is clearing heat and detoxicating
The effect of；Cure mainly irregular menstruation, dysmenorrhea menostasis, lochiorrhagia, edema and little urine, sore swollen toxin.
First starch nutrient powder can provide starch nutriment for the fermentation of strain, and strain can be in nutrition
Strain is bred on substance.
Red yeast rice made of red yeast rice colonizes on polished rice for the mycelium of Aspergillaceae fungi monascus, existing medical value,
There is edible value again.Red yeast rice is sweet in flavor, warm-natured, enters liver, spleen, large intestine channel；With activating blood circulation and dispersing blood clots, invigorating the spleen warm stomach helps digestion and other effects；It can
For treating post partum longtime lochia, stasis abdominal pain, dyspepsia is glutted, red white diarrhea, the diseases such as traumatic injury." book on Chinese herbal medicine asks former " is thought
" disease of all the seven emotions and the six sensory pleasures is in gas so that the puckery person of blood, all preferably helps it ".As the strain to ferment in food, not only containing red in red yeast rice
Aspergillus, also containing saccharomycete etc..
Koji is saccharolytic and yeast preparation, contained by microorganism mainly have head mold, Mucor and a small amount of yeast.It is sending out
Saccharolytic starches down into glucose first during ferment, and breaks down proteins are at amino acid, and then a small amount of yeast is again by Portugal
Grape sugar is converted to alcohol through glycolytic pathway.Koji mainly utilizes the extremely strong saccharification of head mold in koji for fermenting
Energy.It is using starch and protein as primary raw material, and what is played a major role in the production process is the sugar that rhizopus strains generate
Change mould system and albumen enzyme system and starchiness is decomposed by saccharogenesis by saccharification；By albumen enzyme system to the hydrolysed ferment of protein
Effect, generates various amino acid, is in sweet taste and delicate flavour, then passes through the lactic fermentation of the alcoholic fermentation effect and bacterium of yeast again
Effect, is just provided with unique flavor.
Wherein, motherwort for example can be, but be not limited to 15 parts, 16 parts, 18 parts, 20 parts, 22 parts, 24 parts, 26 parts, 28
Part, 30 parts, 32 parts, 34 parts, 36 parts, 38 parts, 40 parts, 42 parts, 44 parts, 46 parts or 48 parts；First starch nutrient powder for example may be used
Think, but is not limited to 8 parts, 9 parts, 10 parts, 11 parts or 12 parts；Red yeast rice for example can be, but be not limited to 1 part, 2 parts, 3 parts, 4 parts or
5 parts；Koji for example can be, but be not limited to 1 part, 2 parts, 3 parts, 4 parts or 5 parts.
And/or the Herba Lycopi tunning is mainly prepared from the following raw materials: 22-47 parts of Herba Lycopi, protein-based nutrition
8-12 parts of powder, 3-7 parts of the second starch nutrient powder and 1-5 parts of koji.
Herba Lycopi bitter, pungent, slightly warm in nature, enter liver, the spleen channel, have the effect of activating microcirculation and removing stasis medicinal, line water detumescence, removing toxicity for eliminating carbuncles；It is main
Control women's menostasis, dysmenorrhea, postpartum stasis abdominal pain, abdominal mass edema, traumatic injury, carbuncle sore tumefacting virus.
Protein-based nutrient powder can provide starch nutriment for the fermentation of strain, and strain can be in nutrients
Strain is bred in matter.
Second starch nutrient powder can generate Mucor, aspergillus or bacterialprotease under appropriate conditions, can incite somebody to action
Breaks down proteins are at amino acid.
Koji is saccharolytic and yeast preparation, contained by microorganism mainly have head mold, Mucor and a small amount of yeast.It is sending out
Saccharolytic starches down into glucose first during ferment, and breaks down proteins are at amino acid, and then a small amount of yeast is again by Portugal
Sugar is converted to alcohol through glycolytic pathway.Koji mainly utilizes the extremely strong saccharification performance of head mold in koji for fermenting.
It is using starch and protein material as primary raw material, and what is played a major role in the production process is the sugar that rhizopus strains generate
Change mould system and albumen enzyme system and starchiness is decomposed by saccharogenesis by saccharification；By albumen enzyme system to the hydrolysed ferment of protein
Effect, generates various amino acid, is in sweet taste and delicate flavour, then passes through the lactic fermentation of the alcoholic fermentation effect and bacterium of yeast again
Effect, is just provided with unique flavor.
Wherein, Herba Lycopi for example can be, but be not limited to 22 parts, 24 parts, 26 parts, 28 parts, 30 parts, 32 parts, 34 parts, 36 parts,
38 parts, 40 parts, 42 parts, 44 parts, 46 parts or 47 parts；Protein-based nutrient powder for example can be, but be not limited to 8 parts, 9 parts, 10 parts,
11 parts or 12 parts；Second starch nutrient powder for example can be, but be not limited to 3 parts, 4 parts, 5 parts, 6 parts, 7 parts；Koji is for example
It can be, but be not limited to 1 part, 2 parts, 3 parts, 4 parts or 5 parts.
The first starch nutrient powder that fermented tcm additive provided by the invention is matched by extra fine quality, red koji fermentation,
Koji and motherwort ferment to obtain motherwort tunning；By the protein-based nutrient powder of extra fine quality proportion, the second starch
Class nutrient powder and sweet wine koji fermentation obtain motherwort tunning；Containing more in motherwort tunning and Herba Lycopi tunning
Active constituent is planted, mutual coordinated between various active constituents has apparent inhibiting effect to pathogenic bacteria, improves body cotton dress
Globulin and antibody level enhance immunity of organisms.
In one preferred embodiment, the motherwort tunning is mainly prepared from the following raw materials: benefit is female
15-35 parts careless, 8-11 parts of the first starch nutrient powder, 1-4 parts of red yeast rice and 1-4 parts of koji；
And/or the Herba Lycopi tunning is mainly prepared from the following raw materials: 22-45 parts of Herba Lycopi, protein-based nutrition
8-11 parts of powder, 3-6 parts of the second starch nutrient powder and 1-4 parts of koji.
In one preferred embodiment, the motherwort tunning is mainly prepared from the following raw materials: benefit is female
19-35 parts careless, 9-11 parts of the first starch nutrient powder, 2-4 parts of red yeast rice and 2-4 parts of koji；
And/or the Herba Lycopi tunning is mainly prepared from the following raw materials: 33-45 parts of Herba Lycopi, protein-based nutrition
9-11 parts of powder, 4-6 parts of the second starch nutrient powder and 2-4 parts of koji.
In one preferred embodiment, the first starch nutrient powder include corn, it is wheat, buckwheat, rice, glutinous
At least one of rice, sorghum, glutinous millet, sweet potato, potato, Chinese yam, taro or cassava, preferably glutinous rice.
In one preferred embodiment, the second starch nutrient powder include corn flour, it is flour, buckwheat, big
At least one of rice flour, glutinous rice flour, sorghum flour, glutinous millet powder, sweet potato flour, dehydrated potato powder, yam flour, taro meal or tapioca starch,
Preferably flour.In one preferred embodiment, the protein-based nutrient powder include semen viciae fabae, pea, mung bean, red bean,
At least one of kidney bean or soya bean, preferably soya bean.
According to the second aspect of the invention, the present invention provides a kind of preparation methods of fermented tcm additive, including
Following steps: motherwort tunning and Herba Lycopi tunning are mixed.
The preparation method of fermented tcm additive provided by the invention is simple, easily grasps, is economical and practical, can open on a large scale
It produces.
In one preferred embodiment, include the following steps:
(a) the first starch nutrient powder is mixed with red yeast rice, is fermented, then mixed with motherwort and koji, fermentation obtains
Motherwort tunning；
(b) protein-based nutrient powder is mixed with the second starch nutrient powder, is fermented, then mixed with Herba Lycopi and koji,
Fermentation obtains Herba Lycopi tunning；
(c) the motherwort tunning that the step (a) obtains and the Herba Lycopi tunning that the step (b) obtains is mixed
It closes to get fermented tcm additive.
In one preferred embodiment, the partial size of the motherwort is 200-300 mesh, preferably 250-300 mesh.
The partial size of motherwort is crushed to 200-300 mesh, in order to guarantee that motherwort comes into full contact with other components, guarantees to fill
Distribute ferment.
Wherein, the partial size of motherwort for example can be, but be not limited to 200 mesh, 210 mesh, 220 mesh, 230 mesh, 240 mesh, 250
Mesh, 260 mesh, 270 mesh, 280 mesh, 290 mesh or 300 mesh.
In one preferred embodiment, the partial size of the Herba Lycopi is 200-300 mesh, preferably 250-300 mesh.
The partial size of motherwort is crushed to 200-300 mesh, in order to guarantee that Herba Lycopi comes into full contact with other components, is guaranteed abundant
Fermentation.
Wherein, the partial size of Herba Lycopi for example can be, but be not limited to 200 mesh, 210 mesh, 220 mesh, 230 mesh, 240 mesh, 250
Mesh, 260 mesh, 270 mesh, 280 mesh, 290 mesh or 300 mesh.
In one preferred embodiment, in the step (a), the fermentation of the first starch nutrient powder and red yeast rice
Temperature be 25-33 DEG C, preferably 25-30 DEG C, and/or, the fermentation time be 25-35, preferably 30-35.
Wherein, fermentation temperature for example can be, but be not limited to 25 DEG C, 26 DEG C, 27 DEG C, 28 DEG C, 29 DEG C, 30 DEG C, 31 DEG C, 32
DEG C or 33 DEG C；Fermentation time for example can be, but be not limited to 25 days, 26 days, 27 days, 28 days, 29 days, 30 days, 31 days, 32 days,
33,34 or 35 days.
In one preferred embodiment, in the step (a), the fermentation time of the motherwort is 8-12 days, excellent
It is selected as 8-10 days.
Wherein, fermentation time for example can be, but be not limited to 8,9,10 days, 11 days or 12 days.
In one preferred embodiment, in the step (b), the protein-based nutrient powder and the second starch are sought
Support powder fermentation temperature be 15-25 DEG C, preferably 18-25 DEG C, and/or, the fermentation time be 1-3, preferably 2-3.
Wherein, fermentation temperature for example can be, but be not limited to 15 DEG C, 16 DEG C, 17 DEG C, 18 DEG C, 19 DEG C, 20 DEG C, 21 DEG C, 22
DEG C, 23 DEG C, 24 DEG C or 25 DEG C；Fermentation time for example can be, but be not limited to 1,2 or 3 days.
In one preferred embodiment, in the step (b), the fermentation time of the Herba Lycopi is 8-12 days, preferably
It is 8-10 days.
Wherein, fermentation time for example can be, but be not limited to 8,9,10 days, 11 days or 12 days.
In one preferred embodiment, dry after the mixing in the step (c), the drying temperature is 45-
55 DEG C, preferably 50-55 DEG C.
Wherein, drying temperature for example can be, but be not limited to 45 DEG C, 46 DEG C, 47 DEG C, 48 DEG C, 49 DEG C, 50 DEG C, 51 DEG C, 52
DEG C, 53 DEG C, 54 DEG C or 55 DEG C.
According to the third aspect of the present invention, the present invention provides a kind of application methods of fermented tcm additive, including
Following steps: the fermented tcm additive that above-mentioned fermented tcm additive or above-mentioned preparation method are prepared individually is fed dynamic
Object is added to mixed feeding animal in animal feed.
The application method of fermented tcm additive provided by the invention is simple, easy to operate, either individually feeding or with
Animal feed mixed feeding has preferable palatability, falls ill to female animals postpartum health care and after reducing newborn cub wean
Rate has positive effect.
In one preferred embodiment, the fermented tcm additive according to animal day feeding amount of dry matter 0.5-
2% independent feeding animals；Or the fermented tcm additive of 0.5-2% is added to mixed feeding animal in animal feed.
In order to facilitate the clearer understanding present invention, below in conjunction with embodiment and comparative example to technical side of the invention
Case is described further.
Embodiment one
Present embodiments provide a kind of fermented tcm additive, including motherwort tunning and Herba Lycopi tunning；
Wherein, motherwort tunning is mainly prepared from the following raw materials: 25 parts of motherwort, 10 parts of glutinous rice, 3 parts of red yeast rice
With 3 parts of koji；
Herba Lycopi tunning is mainly prepared from the following raw materials: 41 parts of Herba Lycopi, 10 parts of soya bean, 5 parts of flour and koji 3
Part.
Embodiment two
Present embodiments provide a kind of fermented tcm additive, including motherwort tunning and Herba Lycopi tunning；
Wherein, motherwort tunning is mainly prepared from the following raw materials: 19 parts of motherwort, 9 parts of glutinous rice, 4 parts of red yeast rice
With 2 parts of koji；
Herba Lycopi tunning is mainly prepared from the following raw materials: 45 parts of Herba Lycopi, 11 parts of soya bean, 6 parts of flour and koji 4
Part.
Embodiment three
Present embodiments provide a kind of fermented tcm additive, including motherwort tunning and Herba Lycopi tunning；
Wherein, motherwort tunning is mainly prepared from the following raw materials: 35 parts of motherwort, 11 parts of glutinous rice, 2 parts of red yeast rice
With 4 parts of koji；
Herba Lycopi tunning is mainly prepared from the following raw materials: 33 parts of Herba Lycopi, 9 parts of soya bean, 4 parts of flour and koji 2
Part.
Example IV
Present embodiments provide a kind of fermented tcm additive, including motherwort tunning and Herba Lycopi tunning；
Wherein, motherwort tunning is mainly prepared from the following raw materials: 15 parts of motherwort, 8 parts of glutinous rice, 5 parts of red yeast rice
With 1 part of koji；
Herba Lycopi tunning is mainly prepared from the following raw materials: 47 parts of Herba Lycopi, 12 parts of soya bean, 7 parts of flour and koji 5
Part.
Embodiment five
Present embodiments provide a kind of fermented tcm additive, including motherwort tunning and Herba Lycopi tunning；
Wherein, motherwort tunning is mainly prepared from the following raw materials: 48 parts of motherwort, 12 parts of glutinous rice, 1 part of red yeast rice
With 5 parts of koji；
Herba Lycopi tunning is mainly prepared from the following raw materials: 22 parts of Herba Lycopi, 8 parts of soya bean, 3 parts of flour and koji 1
Part.
Embodiment six
The preparation method for present embodiments providing a kind of fermented tcm additive, includes the following steps:
(a) glutinous rice is taken, adds bubble saturating, cooks, airing to room temperature adds red yeast rice, mixes thoroughly, and 30 DEG C are made 30, makes for yellow rice wine；It takes
Motherwort crushes as 250 mesh impalpable powders, puts into yellow rice wine and makes, koji is added, continues fermentation 10 days, obtains motherwort fermentation and produces
Object；
(b) soya bean is taken, decladding and to crush be 8 mesh particles adds bubble saturating, cooks, airing to room temperature adds flour, mixes thoroughly, sets
It is spread out on thin bamboo strips used for weaving, keeps 3cm left and right thickness, cover cotton, be placed in shady and cool library, kept for 18 DEG C of room temperature ferment 2 days, for Huang
Beans are made；Herba Lycopi is taken, is crushed as 250 mesh impalpable powders, soya bean is put into and makes, koji is added, continue fermentation 10 days, obtains Herba Lycopi fermentation
Product；
(c) the motherwort tunning that step (a) obtains and the Herba Lycopi tunning that step (b) obtains are mixed, with system
Grain machine is prepared into 20 mesh fine graineds, and 50 DEG C of drying are to get fermented tcm additive.
Comparative example one
This comparative example provides a kind of fermented tcm additive, what is different from the first embodiment is that the weight of motherwort and Herba Lycopi
Amount compares not within protection scope of the present invention.
This comparative example provides a kind of fermented tcm additive, including motherwort tunning and Herba Lycopi tunning；
Wherein, motherwort tunning is mainly prepared from the following raw materials: 13 parts of motherwort, 10 parts of glutinous rice, 3 parts of red yeast rice
With 3 parts of koji；
Herba Lycopi tunning is mainly prepared from the following raw materials: 11 parts of Herba Lycopi, 10 parts of soya bean, 5 parts of flour and koji 3
Part.
Comparative example two
This comparative example provides a kind of fermented tcm additive, what is different from the first embodiment is that the weight of motherwort and Herba Lycopi
Amount compares not within protection scope of the present invention.
This comparative example provides a kind of fermented tcm additive, including motherwort tunning and Herba Lycopi tunning；
Wherein, motherwort tunning is mainly prepared from the following raw materials: 60 parts of motherwort, 10 parts of glutinous rice, 3 parts of red yeast rice
With 3 parts of koji；
Herba Lycopi tunning is mainly prepared from the following raw materials: 48 parts of Herba Lycopi, 10 parts of soya bean, 5 parts of flour and koji 3
Part.
Comparative example three
This comparative example provides a kind of fermented tcm additive, what is different from the first embodiment is that producing without motherwort fermentation
Object.
Comparative example four
This comparative example provides a kind of fermented tcm additive, unlike embodiment six, is free of Herba Lycopi tunning.
Comparative example five
This comparative example provides a kind of preparation method of fermented tcm additive, unlike embodiment six, step (a)
Middle motherwort tunning preparation method is different.
Wherein, step (a): glutinous rice, motherwort, bacillus subtilis, saccharomycete and lactic acid bacteria being mixed, stirred evenly,
Water is added, water temperature is 55 ± 3 DEG C, is stirred evenly, standing for fermentation obtains motherwort tunning.
Comparative example six
This comparative example provides a kind of preparation method of fermented tcm additive, unlike embodiment six, step (b)
Middle Herba Lycopi tunning preparation method is different.
Wherein, step (b): soya bean, flour, Herba Lycopi, bacillus subtilis, saccharomycete and lactic acid bacteria are mixed, and stirring is equal
It is even, water is added, water temperature is 55 ± 3 DEG C, is stirred evenly, standing for fermentation obtains motherwort tunning.
Comparative example seven
This comparative example provides a kind of preparation method of Chinese medicine additive, includes the following steps: 25 parts of motherwort, glutinous rice 10
Part, 41 parts of Herba Lycopi, 10 parts of soya bean and 5 parts of flour mixing, crush as 250 mesh impalpable powders to get Chinese medicine additive.
Influence of one zymotechnique of test example to fermented tcm additive quality
I. material: red yeast rice (Hebei Lin Shi prepared slices of Chinese crude drugs Co., Ltd)；Motherwort (the limited public affairs of Palestine and China's Cologne prepared slices of Chinese crude drugs
Department)；Herba Lycopi (Cologne prepared slices of Chinese crude drugs Co., Ltd of Palestine and China)；Koji (Angel Yeast Co., Ltd)；Glutinous rice, soya bean, face
Powder (commercially available).
Experimental animal: Kunming mouse, SPF grades, weight 18-22g, half male and half female, totally 30, by Sichuan Province's medical science
Animal center offer, animal certificate number SYXK (army) 2002-005 are tested in academic test (examination).Animal feeding is closed in barrier animal room, animal house
Lattice card SYXK (army) 2002-005.Room temperature (20 ± 2) DEG C, relative humidity 60-70%, well-ventilated, environment quiet, indoor guarantor
12h illumination is held, 12h is dark, and periodically sterilizes.
Technique: six groups of embodiment: formula provided by embodiment one is prepared according to the preparation method of embodiment six.
Five groups of comparative example: formula provided by embodiment one is prepared according to the preparation method of comparative example five.
Six groups of comparative example: formula provided by embodiment one is prepared according to the preparation method of comparative example six.
Seven groups of comparative example: formula provided by embodiment one is prepared according to the preparation method of comparative example seven.
Control group: taking 25 parts of motherwort and 41 parts of Herba Lycopi mixing, crushes as 250 mesh impalpable powders, as reference substance.
II. pharmacodynamic test: taking sow due to farrow to be randomly divided into 6 groups, and respectively blank group, control group and test group be (respectively
Seven groups of six groups of embodiment, five groups of comparative example, six groups of comparative example and comparative example).Test group is fed by 1% spice, and control group presses 1%
Spice is fed, and blank group feeds straw end by 1% spice, feeds 5 days before sows farrowing, and postpartum feeds 7 days, in addition to feed,
Its rearing conditions is identical, observes and records each group sow respectively and is averaged stages of labor (averagestages of labor, abbreviation ASL),
Prolonged lochia (prolonged lochia, abbreviation PL) disease incidence, sow postpartum triad (intimitis, breast in uterus
Scorching and agalasisa and lactation are insufficient, abbreviation MMA) disease incidence and piglet disease incidence and piglet daily gain average value (ADG).
Compared with the control group by the result of test group, one of index obtains a "+" better than control group, with control group phase
When then ignoring, quite or it is worse than control group with blank group and is then chosen as "-", a "+" and a "-" are cancelled out each other, be the results are shown in Table
1。
1 postpartum health care functional evaluation result of table
As seen from the above table, six groups of embodiment of average stages of labor ASL, PL disease incidence, MMA disease incidence and piglet disease incidence and son
Pig ADG is superior to five to seven group of comparative example, control group and blank group, illustrates the fermentation obtained using preparation method of the invention
Chinese medicine additive greatly improves postpartum health care for sows function.
III. toxicological test: taking mouse to be randomly divided into 6 groups, and every group 10, half male and half female, respectively blank group, control group
With test group (respectively seven groups of six groups of embodiment, five groups of comparative example, six groups of comparative example and comparative example).Control group presses 38gkg-1
Daily dosage stomach-filling reference substance suspension, test group press 38gkg-1Daily dosage difference stomach-filling fermented tcm additive it is mixed
Suspension, the capacity distilled water such as blank group stomach-filling even fill 14 days, the free diet of animal during administration.Daily observation administration front and back is dynamic
The appearance sign of object, whether there is or not abnormal secretions for the variation of behavioral activity hair, stool and urine shape and color, eye, ear, mouth, nose, anus
Deng.0,1,3,7,11 and 14 day weighing the weight of animals is being administered respectively, is calculating growth rate.After successive administration 14 days, mouse plucks eye
Ball takes blood, separates serum, detects glutamic-pyruvic transaminase (ALT), glutamic-oxalacetic transaminease (AST), urea nitrogen (BUN), inosine (CREA), alkali
Acid phosphatase (ALP), total protein (TP), albumin (ALB), globulin (GLO), A/G, total bilirubin (TBIL), glucose
(Glu) and total cholesterol (CHOL) index.Animal is put to death after taking blood, to the heart, liver and spleen, lung, kidney, brain, sexual gland, thyroid gland, thymus gland
It is visually observed with ileum etc., weighs and calculate organ coefficient.Liver, nephridial tissue are taken, is fixed with 10% neutral formalin solution, is passed through
Graded ethanol dehydration, the transparent paraffin embedding of dimethylbenzene, slice (4-5 μm thick) and HE are dyed, observation tissue disease under optical microscopy
Reason variation.
Appearance sign observes each group without dead example, general signs no abnormality seen.
Compared with blank group, the heart of control group and test group mouse, liver and spleen, lung, kidney, brain, sexual gland, thyroid gland, thymus gland and
The Organ weights such as ileum and organ coefficient difference is not significant.
Compared with blank group, in Biochemical Indices In Serum, control group and test group change smaller (difference is not significant), ALP,
The variation of the indexs such as ALB, TP, GLO, A/G, TBIL, CHOL and Glu is unobvious.Liver/kidney side effect evaluation, the results are shown in Table 2, table 3.
2 liver side effect evaluation result of table
| Grouping | ALT/U·L-1 | AST/U·L-1 | Overall merit |
| Six groups of embodiment | 31.82±4.54 | 95.76±11.24 | Normally |
| Five groups of comparative example | 32.04±7.63 | 96.71±9.67 | Normally |
| Six groups of comparative example | 31.25±8.14 | 95.87±11.23 | Normally |
| Seven groups of comparative example | 31.2±5.46 | 96.32±11.08 | Normally |
| Control group | 32.21±6.13 | 96.06±10.54 | Normally |
| Blank group | 31.63±2.76 | 96.13±11.06 | Normally |
3 renal adverse effects evaluation result of table
| Grouping | BUN/mmol·L-1 | CREA/μmol·L-1 | Overall merit |
| Six groups of embodiment | 6.84±1.60 | 54.06±8.16 | Normally |
| Five groups of comparative example | 6.88±0.98 | 54.14±7.82 | Normally |
| Six groups of comparative example | 6.90±1.34 | 55.71±6.45 | Normally |
| Seven groups of comparative example | 6.89±1.05 | 54.66±8.01 | Normally |
| Blank group | 6.92±1.12 | 54.68±7.62 | Normally |
| Control group | 7.04±2.14 | 54.56±6.73 | Normally |
As seen from the above table, compared with blank group, ALT, AST, BUN and CREA index of each administration group, difference is unobvious,
Successive administration 14 days under higher dosage, test group Mouse Liver/renal function is not damaged, and liver/kidney side effect is chosen as " normal ".
Consolidated statement 1, table 2, table 3 are analyzed, the fermented tcm additive postpartum health care obtained using preparation method of the invention
Function greatly improves, and liver/kidney side effect reaction does not also occur, shows that zymotechnique of the invention has Herba Lycopi and motherwort
Synergy and attenuation effect.
III. Palatability evaluation: control group is freely eaten by 1% dosage spice for healthy swinery, and test group is (respectively
Seven groups of six groups of embodiment, three groups of comparative example, four groups of comparative example, five groups of comparative example, six groups of comparative example and comparative example) press 1% use
Amount spice is freely eaten for healthy swinery, and blank group feeds chow diet；Record feeding situation, it is corresponding suitable with blank group feed intake
Mouth property is " general ", and the palatability of corresponding drug is evaluated according to each group feeding situation, and evaluation criterion is shown in Table 4, and evaluation result is shown in Table
5。
4 Palatability evaluation standard of table
| Palatability evaluation | Judgment criteria |
| It is excellent | Compared to the blank group, feed intake increases |
| Generally | Compared to the blank group, feed intake is unchanged |
| Difference | Compared to the blank group, feed intake declines |
5 Palatability evaluation result of table
As seen from the above table, six groups of embodiment of palatability is " excellent ", and the palatability of five to seven group of comparative example and control group is
" poor " illustrates that the palatability for the fermented tcm additive that preparation method of the invention obtains is substantially better than other groups.
The Chinese medicine additive Quality evaluation of Different Preparation, the results are shown in Table 6.
6 Quality evaluation result of table
| Grouping | Postpartum health care function | Liver side effect | Renal adverse effects | Palatability evaluation | Overall merit |
| Six groups of embodiment | +++++ | Normally | Normally | It is excellent | It is excellent |
| Five groups of comparative example | - | Normally | Normally | Difference | Difference |
| Six groups of comparative example | - | Normally | Normally | Difference | Difference |
| Seven groups of comparative example | - | Normally | Normally | Difference | Difference |
As seen from the above table, since five to seven group of comparative example has no toxicity, but in terms of health-care effect and palatability all compared with
Difference, overall merit are still " poor "；Six groups of Quality evaluations of embodiment are " excellent ".
Influence of two different ratios of raw materials of test example to fermented tcm additive quality
I. material: identical as test example one (I).
Experimental animal: identical as test example one (I).
Conceptual design: 7 are specifically shown in Table.
The raw material proportioning scheme of 7 fermented tcm additive of table
Feeding is provided according to table 7, is prepared respectively according to the preparation method of embodiment six.
Control group: taking 25 parts of motherwort and 41 parts of Herba Lycopi mixing, crushes as 250 mesh impalpable powders, as reference substance.
II. pharmacodynamic test: identical as test example one (II).
Compared with the control group by the result of test group, one of index obtains a "+" better than control group, with control group phase
When then ignoring, quite or it is worse than control group with blank group and is then chosen as "-", a "+" and a "-" are cancelled out each other, be the results are shown in Table
8。
8 postpartum health care functional evaluation result of table
As seen from the above table, fermented tcm provided by one to five group of the embodiment of the present invention and one, three and four group of comparative example adds
Add agent postpartum health care function to be superior to control group, fermented tcm additive postpartum health care function provided by two groups of comparative example with it is right
Quite according to group, illustrate that different ratios of raw materials combination has an impact to the function curative effect of fermented tcm additive, but do not find this shadow
Ringing has apparent regularity, and different ratios of raw materials is combined to ASL, PL disease incidence, MMA disease incidence, piglet disease incidence and piglet ADG
Influence it is different.
III. toxicological test: identical as test example one (III).
Compared with blank group, the indexs such as ALP, ALB, TP, GLO, A/G, TBIL, CHOL and Glu of each administration group change not
Obviously.Liver/kidney side effect evaluation, the results are shown in Table 9, table 10.
9 liver side effect evaluation result of table
| Grouping | ALT/U·L-1 | AST/U·L-1 | Overall merit |
| One group of embodiment | 30.32±7.96 | 96.70±21.96 | Normally |
| Two groups of embodiment | 31.68±8.48 | 95.35±15.04 | Normally |
| Three groups of embodiment | 31.79±8.02 | 94.35±12.97 | Normally |
| Example IV group | 30.46±4.52 | 96.98±10.65 | Normally |
| Five groups of embodiment | 31.19±8.66 | 95.36±14.48 | Normally |
| One group of comparative example | 31.38±4.43 | 96.73±10.22 | Normally |
| Two groups of comparative example | 31.26±5.08 | 95.22±14.64 | Normally |
| Three groups of comparative example | 31.56±5.44 | 96.31±9.46 | Normally |
| Four groups of comparative example | 32.10±6.12 | 95.11±10.33 | Normally |
| Control group | 31.36±6.44 | 96.94±18.52 | Normally |
| Blank group | 31.12±2.62 | 96.16±10.46 | Normally |
10 renal adverse effects evaluation result of table
| Grouping | BUN/mmol·L-1 | CREA/μmol·L-1 | Overall merit |
| One group of embodiment | 7.23±2.15 | 53.65±8.92 | Normally |
| Two groups of embodiment | 7.23±1.25 | 56.19±9.87 | Normally |
| Three groups of embodiment | 6.78±1.52 | 53.63±5.36 | Normally |
| Example IV group | 6.37±1.43 | 55.03±8.47 | Normally |
| Five groups of embodiment | 6.56±1.76 | 53.82±8.67 | Normally |
| One group of comparative example | 7.53±0.86 | 54.71±7.86 | Normally |
| Two groups of comparative example | 6.96±1.24 | 54.72±6.32 | Normally |
| Three groups of comparative example | 6.91±1.07 | 54.12±8.10 | Normally |
| Four groups of comparative example | 6.87±1.23 | 55.01±7.09 | Normally |
| Control group | 7.04±1.61 | 54.66±5.32 | Normally |
| Blank group | 6.87±0.89 | 54.06±6.92 | Normally |
As can be known from the above table, compared with blank group, ALT, AST, BUN and CREA index of each administration group, difference is unobvious,
Successive administration 14 days under higher dosage, do not find liver/kidney toxicity, and liver/kidney side effect is chosen as " normal ".
III. Palatability evaluation: identical as test example one (III), evaluation results are shown in Table 11.
11 Palatability evaluation result of table
As seen from the above table, influence of the fermented tcm additive of different ratios of raw materials to palatability is different, and this shadow
Ring not shown regularity.
The Chinese medicine additive Quality evaluation of different ratios of raw materials, the results are shown in Table 12.
12 Quality evaluation result of table
| Grouping | Postpartum health care function | Liver side effect | Renal adverse effects | Palatability evaluation | Overall merit |
| One group of embodiment | +++++ | Normally | Normally | It is excellent | It is excellent |
| Two groups of embodiment | +++++ | Normally | Normally | It is excellent | It is excellent |
| Three groups of embodiment | ++++ | Normally | Normally | Generally | It is excellent |
| Example IV group | +++ | Normally | Normally | Generally | It is excellent |
| Five groups of embodiment | +++ | Normally | Normally | It is excellent | It is excellent |
| One group of comparative example | ++ | Normally | Normally | Difference | Difference |
| Two groups of comparative example | - | Normally | Normally | It is excellent | Difference |
| Three groups of comparative example | + | Normally | Normally | Generally | Difference |
| Four groups of comparative example | + | Normally | Normally | Generally | Difference |
As seen from the above table, it is performed poor in terms of palatability due to one group of comparative example, although its postpartum health care effect is fine,
Also toxicity is had no, overall merit is still " poor "；Two groups of comparative example are performed well in terms of palatability, also have no malicious secondary anti-
It answers, but its postpartum health care poor effect, overall merit are still " poor "；Three to four group of comparative example has no toxicity, but protects
All general in terms of strong effect and palatability, overall merit is still " poor "；One to five group Quality evaluation of embodiment is
" excellent ".
The postpartum health care effect of one fermented tcm additive on sow of effect test
Material: formula provided by embodiment one is prepared according to the preparation method of embodiment six.
It is prepared being formulated provided by comparative example one to four respectively according to the preparation method of embodiment six.
It is prepared being formulated provided by embodiment one respectively according to the preparation method of comparative example five to seven.
Control group: taking 25 parts of motherwort and 41 parts of Herba Lycopi mixing, crushes as 250 mesh impalpable powders, as reference substance.
Case: the above advanced age farrowing sow of 8 tire of Shuangliu County pig farm 90.
Method: 10 groups are randomly divided under identical rearing conditions, every group 9, respectively blank group, control group and test group
(respectively one group of embodiment, one group of comparative example, two groups of comparative example, three groups of comparative example, four groups of comparative example, five groups of comparative example, comparison
Seven groups of six groups of example and comparative example).Test group is fed by 1.0% spice, and control group is fed by 1% spice, just before giving birth preceding continuous use 5
It, blank group is raised by daily feeding manner, is not administered；Record ASL, PL disease incidence, MMA disease incidence, piglet disease incidence and son
Pig ADG, the results are shown in Table 13.
The postpartum health care of 13 fermented tcm additive on sow of table is investigated
As seen from the above table, the postpartum health care effect of embodiment a pair of sow is better than other groups, illustrates fermented tcm of the present invention
The postpartum health care effect of additive on sow is good.
Control efficiency of the two fermented tcm additive of effect test to PMWS
Material: formula provided by embodiment one is prepared according to the preparation method of embodiment six.
It is prepared being formulated provided by comparative example one to four respectively according to the preparation method of embodiment six.
It is prepared being formulated provided by embodiment one respectively according to the preparation method of comparative example five to seven.
Control group: taking 25 parts of motherwort and 41 parts of Herba Lycopi mixing, crushes as 250 mesh impalpable powders, as reference substance.
Test pig farm: the multiple field Shuangliu County postweaning multisystem exhaustion syndrome (PMWS).
Method: 10 groups are randomly divided under identical rearing conditions, every group 9, respectively blank group, control group and test group
(respectively one group of embodiment, one group of comparative example, two groups of comparative example, three groups of comparative example, four groups of comparative example, five groups of comparative example, comparison
Seven groups of six groups of example and comparative example).Test group is fed by 1.0% spice, and control group is fed by 1% spice, and wean front and back is each continuous
Medication 7 days, blank group was raised by daily feeding manner, was not administered；PMWS incidence is recorded, the results are shown in Table 14.
14 fermented tcm additive of table investigates the control efficiency of pig PMWS
| Group | PMWS disease incidence (%) |
| One group of embodiment | 0 |
| One group of comparative example | 8 |
| Two groups of comparative example | 10 |
| Three groups of comparative example | 5 |
| Four groups of comparative example | 6 |
| Five groups of comparative example | 15 |
| Six groups of comparative example | 13 |
| Seven groups of comparative example | 12 |
| Control group | 11 |
| Blank group | 27 |
As seen from the above table, test group is better than other groups to the control efficiency of pig PMWS, illustrates fermented tcm additive to pig
The control efficiency of PMWS is good.
Influence of the three fermented tcm additive of effect test to pig farm RSY
Material: formula provided by embodiment one is prepared according to the preparation method of embodiment six.
It is prepared being formulated provided by comparative example one to four respectively according to the preparation method of embodiment six.
It is prepared being formulated provided by embodiment one respectively according to the preparation method of comparative example five to seven.
Control group: taking 25 parts of motherwort and 41 parts of Herba Lycopi mixing, crushes as 250 mesh impalpable powders, as reference substance.
Test pig farm: Shuangliu County home-bred and autophytic pig farm.
Method: randomly selecting sow under identical rearing conditions and be divided into 10 groups, every group 9, respectively blank group, control group
With test group (respectively one group of embodiment, one group of comparative example, two groups of comparative example, three groups of comparative example, four groups of comparative example, comparative example
Seven groups of five groups, six groups of comparative example and comparative example), test group is fed by 1.0% spice, and control group is fed by 1% spice, antenatal company
Continuous medication 5 days, postpartum continuous use 15 days；Test group piglet is fed by 1.0% spice, and control group piglet is fed by 1% spice,
Continuous use 5 days, continuous use 10 days after wean before weaning；Blank group group is raised by daily feeding manner, is not administered；Record is each
The total investment of group and Gross Output calculate RSY (single head sow year rate of return on investment), RSY=(Gross Output-is always put into)/total investment, knot
Fruit is shown in Table 15.
Influence of the 15 fermented tcm additive of table to pig farm RSY is investigated
As seen from the above table, test group is better than other groups in terms of improving pig farm RSY, illustrates that fermented tcm additive is improving
Effect in terms of the RSY of pig farm is good.
Finally, it should be noted that the above embodiments are only used to illustrate the technical solution of the present invention., rather than its limitations；To the greatest extent
Pipe present invention has been described in detail with reference to the aforementioned embodiments, those skilled in the art should understand that: its according to
So be possible to modify the technical solutions described in the foregoing embodiments, or to some or all of the technical features into
Row equivalent replacement；And these are modified or replaceed, various embodiments of the present invention technology that it does not separate the essence of the corresponding technical solution
The range of scheme.
Claims (10)
1. a kind of fermented tcm additive, which is characterized in that including motherwort tunning and Herba Lycopi tunning；
Preferably, the raw material of the motherwort fermentation includes motherwort, and the raw material of the Herba Lycopi fermentation includes Herba Lycopi, and the benefit is female
The weight ratio of grass and Herba Lycopi is (15-48): (22-47), further preferably (15-45): (25-45).
2. fermented tcm additive according to claim 1, which is characterized in that the motherwort tunning is mainly by such as
Lower raw material is prepared: 15-48 parts of motherwort, 8-12 parts of the first starch nutrient powder, 1-5 parts of red yeast rice and 1-5 parts of koji；
And/or the Herba Lycopi tunning is mainly prepared from the following raw materials: 22-47 parts of Herba Lycopi, protein-based nutrient powder 8-
12 parts, 3-7 parts of the second starch nutrient powder and 1-5 parts of koji.
3. fermented tcm additive according to claim 2, which is characterized in that the motherwort tunning is mainly by such as
Lower raw material is prepared: 15-35 parts of motherwort, 8-11 parts of the first starch nutrient powder, 1-4 parts of red yeast rice and 1-4 parts of koji；
And/or the Herba Lycopi tunning is mainly prepared from the following raw materials: 22-45 parts of Herba Lycopi, protein-based nutrient powder 8-
11 parts, 3-6 parts of the second starch nutrient powder and 1-4 parts of koji.
4. fermented tcm additive according to claim 2, which is characterized in that the motherwort tunning is mainly by such as
Lower raw material is prepared: 19-35 parts of motherwort, 9-11 parts of the first starch nutrient powder, 2-4 parts of red yeast rice and 2-4 parts of koji；
And/or the Herba Lycopi tunning is mainly prepared from the following raw materials: 33-45 parts of Herba Lycopi, protein-based nutrient powder 9-
11 parts, 4-6 parts of the second starch nutrient powder and 2-4 parts of koji.
5. fermented tcm additive according to claim 2, which is characterized in that the first starch nutrient powder includes jade
At least one of rice, wheat, buckwheat, rice, glutinous rice, sorghum, glutinous millet, sweet potato, potato, Chinese yam, taro or cassava, preferably
For glutinous rice；
And/or the second starch nutrient powder includes corn flour, flour, buckwheat, rice meal, glutinous rice flour, sorghum flour, Huang
At least one of rice flour, sweet potato flour, dehydrated potato powder, yam flour, taro meal or tapioca starch, preferably flour；
And/or the protein-based nutrient powder includes at least one of semen viciae fabae, pea, mung bean, red bean, kidney bean or soya bean, it is excellent
It is selected as soya bean.
6. a kind of method for preparing the described in any item fermented tcm additives of claim 1-5, which is characterized in that including as follows
Step: motherwort tunning and Herba Lycopi tunning are mixed.
7. the preparation method of fermented tcm additive according to claim 6, which comprises the steps of:
(a) the first starch nutrient powder is mixed with red yeast rice, is fermented, then mixed with motherwort and koji, fermentation obtains beneficial mother
Careless tunning；
(b) protein-based nutrient powder is mixed with the second starch nutrient powder, is fermented, then mixed with Herba Lycopi and koji, fermented
Obtain Herba Lycopi tunning；
(c) the motherwort tunning that the step (a) obtains and the Herba Lycopi tunning that the step (b) obtains are mixed,
Up to fermented tcm additive.
8. the preparation method of fermented tcm additive according to claim 6, which is characterized in that the partial size of the motherwort
For 200-300 mesh, preferably 250-300 mesh；
And/or the partial size of the Herba Lycopi is 200-300 mesh, preferably 250-300 mesh.
9. the preparation method of fermented tcm additive according to claim 6, which is characterized in that in the step (a), institute
The fermentation temperature for stating the first starch nutrient powder and red yeast rice is 25-33 DEG C, preferably 25-30 DEG C, and/or, the fermentation time
It is 25-35, preferably 30-35；
And/or in the step (a), the fermentation time of the motherwort is 8-12, preferably 8-10；
And/or in the step (b), the fermentation temperature of the protein-based nutrient powder and the second starch nutrient powder is 15-25
DEG C, preferably 18-25 DEG C, and/or, the fermentation time is 1-3, preferably 2-3；
And/or in the step (b), the fermentation time of the Herba Lycopi is 8-12, preferably 8-10；
Dry after the mixing and/or in the step (c), the drying temperature is 45-55 DEG C, preferably 50-55 DEG C.
10. a kind of application method of fermented tcm additive includes the following steps: the described in any item hairs of claim 1-5
The fermented tcm additive that ferment Chinese medicine additive or the described in any item preparation methods of claim 6-9 are prepared individually is fed
Animal is added to mixed feeding animal in animal feed；
Preferably, the fermented tcm additive according to animal day feeding amount of dry matter the independent feeding animals of 0.5-2%；Or it will
The fermented tcm additive of 0.5-2% is added to mixed feeding animal in animal feed.
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