CN109077938A - A kind of microneedle array elastic hydrogel facial mask - Google Patents
A kind of microneedle array elastic hydrogel facial mask Download PDFInfo
- Publication number
- CN109077938A CN109077938A CN201811057107.4A CN201811057107A CN109077938A CN 109077938 A CN109077938 A CN 109077938A CN 201811057107 A CN201811057107 A CN 201811057107A CN 109077938 A CN109077938 A CN 109077938A
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- CN
- China
- Prior art keywords
- microneedle array
- elastic hydrogel
- hydrogel layer
- elastic
- layer
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- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/0212—Face masks
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/02—Cosmetics or similar toiletry preparations characterised by special physical form
- A61K8/04—Dispersions; Emulsions
- A61K8/042—Gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/08—Anti-ageing preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/10—General cosmetic use
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/80—Process related aspects concerning the preparation of the cosmetic composition or the storage or application thereof
- A61K2800/91—Injection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0046—Solid microneedles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M37/00—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin
- A61M37/0015—Other apparatus for introducing media into the body; Percutany, i.e. introducing medicines into the body by diffusion through the skin by using microneedles
- A61M2037/0053—Methods for producing microneedles
Abstract
The present invention discloses a kind of microneedle array elastic hydrogel facial mask.The microneedle array elastic facial mask includes elastic hydrogel layer and microneedle array layer, and elastic hydrogel layer stores beautifying nourishing ingredient, and elastic hydrogel layer includes elastic hydrogel；Microneedle array layer includes microneedle array and flexible substrates；Microneedle array is fixed on the upper epidermis of flexible substrates, microneedle array is from the lower surface of elastic hydrogel layer insertion elastic hydrogel layer, and the micropin top of microneedle array does not penetrate the upper surface of elastic hydrogel layer, which has the advantages that structure is simple, practical and convenient.
Description
Technical field
The present invention relates to micropin technical field, especially a kind of microneedle array elastic hydrogel facial mask.
Background technique
Face mask film is a kind of mode of common beautifying face and moistering lotion, but the mode of traditional face mask film comes with some shortcomings.
Due to the barrier action of human skin keratinocyte's layer, nutritional ingredient is difficult to be absorbed in cuticula to skin histology, causes to pass
Surface application film method face mask film time of system is long and the absorptivity of nutritional ingredient is low.
People begin trying the mode using micropin beauty, using many small syringe needles on micropin idler wheel, in facial skin
It perforates on skin, increases cutaneous permeability, enable active constituent effectively penetrate into skin, then be equipped with wrinkle, whitening, repair, remove scar etc.
Special efficacy product, so that it is equivalent to reach treatment scar, skin whitening, improvement eye wrinkle-removing, black eye, tightening and promotion facial tissue
Fruit.Micropin puncture simultaneously can stimulate skin, promote ossein hyperplasia, the thickness of hyperplasia skin epidermis, effective anti-aging.
But there are following defects using the mode of idler wheel micropin: 1. this method need first to puncture using idler wheel micropin,
Nutritional ingredient transmission, complex steps and consuming time is long are given again.2. idler wheel micropin contacts the multiple regions of skin of face, it is easy
Lead to the cross-infection of skin of face.
Summary of the invention
To solve the above problems, the present invention provides the microneedle array elastic hydrogel face that a kind of structure is simple, practical and convenient
Film.The technical solution adopted by the present invention is that:
A kind of microneedle array elastic hydrogel facial mask, including elastic hydrogel layer and microneedle array layer；The elasticity water-setting
Glue-line stores beautifying nourishing ingredient, and the elastic hydrogel layer includes elastic hydrogel；The microneedle array layer includes micropin
Array and flexible substrates；The microneedle array is fixed on the upper epidermis of the flexible substrates, and the microneedle array is from the elasticity
The lower surface of hydrogel layer is inserted into the elastic hydrogel layer, and the upper epidermis of the flexible substrates and the elastic hydrogel
The following table face contact of layer, the microneedle array does not penetrate the upper surface of the elastic hydrogel layer, if the elastic hydrogel layer
By compressive deformation, the micropin of the microneedle array penetrates the upper surface of the elastic hydrogel layer, is pierced into skin.
Preferably, 1~2 millimeter of the thickness of the elastic hydrogel layer, the micropin height in the microneedle array is 500~
1800 microns, the spacing between adjacent micropin is 1 millimeter.Under this condition, the microneedle array is from the elastic hydrogel layer
Lower surface is inserted into the elastic hydrogel layer, and when the elastic hydrogel layer is uncompressed deformation, the microneedle array
The upper surface of the elastic hydrogel layer is not penetrated, specifically: the microneedle array is from the lower surface of the elastic hydrogel layer
It is inserted into the elastic hydrogel layer, and the following table face contact of the upper epidermis of the flexible substrates and the elastic hydrogel layer,
The micropin top of the microneedle array is 200~500 microns at a distance from the upper surface of the elastic hydrogel layer, microneedle array
It is inserted into elastic hydrogel layer, if the distance of the micropin top of microneedle array and elastic hydrogel layer upper surface is too short to be easy to cause thorn
The micropin for entering skin is too long, user can facial bleeding, have feeling of pain, apart from too long, it is preferably micro- effect may not be able to be formed
Hole transmission channel, thus preferred embodiment when microneedle array be inserted into elastic hydrogel layer after, the micropin top of the microneedle array with
The distance of the upper surface of the elastic hydrogel layer has preferable using effect when being 200~500 microns.
In use, micropin, which needs to be pierced into skin, forms micropore transmission channel, therefore, microneedle array preferably has certain rigidity
Biocompatible material, specifically, the microneedle array is prepared by PLGA or PMMA or epoxy resin or the micropin
The material of array can also use the composite material with biocompatible coating or coating.PLGA is poly (lactic acid-glycolic acid)
The english abbreviation of copolymer, PMMA are the english abbreviations of polymethyl methacrylate.
Preferably, the microneedle array structure is solid array of microneedles.
Preferably, the elastic hydrogel layer stores beautifying nourishing ingredient, specifically: the beautifying nourishing ingredient is uniform
It is distributed in the elastic hydrogel.
The material of the flexible substrates is flexible material, flexible material specifically may be selected latex or PVC or silk woven fabric or
Pure cotton fiber woven fabric.PVC is the english abbreviation of polyvinyl chloride.
Microneedle array elastic hydrogel facial mask provided by the present invention, by the microneedle array elastic hydrogel face when use
Film is placed on skin of face, then gently pats flexible substrates, and during gently patting, elastic hydrogel is laminated compression deformation, micro-
The micropin top of needle array penetrates elastic hydrogel layer and is pierced into skin, forms micropore transmission channel, after beating, elastic water-setting
Glue-line restores to the original state, and micropin returns in elastic hydrogel layer, and the beautifying nourishing ingredient stored by elastic hydrogel layer passes through micro-
Hole transmission channel enters skin.After micropore transmission channel closure, puncture can be patted again and forms new micropore transmission channel,
Improve the absorption efficiency of skin.
The beneficial effects of the present invention are:
1, easily conformal with skin using flexible substrates, user feels more comfortable.Micropin is punctured without pain, not bleeding,
It can be healed rapidly using rear skin, securely and reliably.
2, the facial mask is practical and convenient by the way of microneedle array puncture, only need to gently clap, and can form micropore biography
Defeated channel enables beautifying nourishing ingredient effectively penetrate into skin.
3, structure is simple, is easy to be mass produced.
Detailed description of the invention
Fig. 1 is the structural schematic diagram of microneedle array elastic hydrogel facial mask in the embodiment of the present invention；
Fig. 2 is that microneedle array elastic hydrogel facial mask is placed in schematic diagram on skin in the embodiment of the present invention；
Fig. 3 is microneedle array elastic hydrogel facial mask puncture process schematic diagram in the embodiment of the present invention；
Fig. 4 is microneedle array elastic hydrogel facial mask schematic diagram of transmission process in the embodiment of the present invention.
Specific embodiment
Below in conjunction with drawings and examples, the invention will be further described.
A kind of microneedle array elastic hydrogel facial mask as shown in Fig. 1, including elastic hydrogel layer 3 and microneedle array
Layer；Elastic hydrogel layer includes elastic hydrogel, and beautifying nourishing ingredient 4 is evenly distributed in elastic hydrogel；Microneedle array layer
Including microneedle array 2 and flexible substrates 1；Microneedle array 2 is fixed on the upper epidermis of flexible substrates 1, and microneedle array 2 is from elastic water-setting
In the lower surface insertion elastic hydrogel layer 3 of glue-line 3, and the lower surface of the upper epidermis of flexible substrates 1 and elastic hydrogel layer 3 is tight
Closely connected conjunction, microneedle array 2 do not penetrate the upper surface of elastic hydrogel layer 3.
In the present embodiment, elastic hydrogel layer 3 with a thickness of 1.5 millimeters, in the elastic hydrogel of elastic hydrogel layer 3
It is evenly distributed with the beautifying nourishings such as amino acid, collagen, hyaluronic acid ingredient 4, the flexible substrates 1 of fixed microneedle array 2 are
The woven fabric of pure cotton fiber, microneedle array 2 are prepared using the composite material with biocompatible coating, phase in microneedle array 2
Spacing between adjacent micropin is 1 millimeter, and the height of microneedle array 2 is 1200 microns, and microneedle array 2 is from elastic hydrogel layer 3
Lower surface is inserted into elastic hydrogel layer 3, and the lower surface of the upper epidermis of flexible substrates 1 and elastic hydrogel layer 3 fits closely,
The distance of the upper surface on the micropin top and elastic hydrogel layer 3 of microneedle array 2 is 300 microns.
In the present embodiment, this facial mask is made of following steps:
(1) it is 1200 microns of microneedle array 2 that micropin height is made in flexible substrates 1, and 2 surface of microneedle array into
The improvement of row biocompatibility；
(2) beautifying nourishing ingredient is stored among the elastic hydrogel layer 3 of 1.5 millimeters thicks, then microneedle array 2 is inserted into
3 lower surface of elastic hydrogel layer, flexible substrates 1 and 3 lower surface of elastic hydrogel layer fit closely, the micropin top of microneedle array 2
It holds with 300 microns of distance of the upper surface of elastic hydrogel layer 3 to get the microneedle array elastic hydrogel in the embodiment of the present invention
Facial mask.
As shown in Fig. 2, microneedle array elastic hydrogel facial mask is placed on skin 5, elastic hydrogel layer 3 and skin 5
Directly contact.
As shown in Fig. 3, the outer surface of flexible substrates 1 is gently patted, elastic hydrogel layer 3 generates compressive deformation, micropin
The micropin of array 2 penetrates the upper surface of elastic hydrogel layer 3, is pierced into skin 5, forms micropore transmission channel 6 on the skin.
As shown in Fig. 4, after beating, elastic hydrogel layer 3 restores to the original state, and microneedle array 2 returns to elastic water-setting
In glue-line 3, nutritional ingredient 4 enters skin by micropore transmission channel 6, after micropore transmission channel closure, can pat again
Puncture forms new micropore transmission channel, improves the absorption efficiency of skin.
Microneedle array elastic hydrogel facial mask in the present embodiment uses flexible substrates, easily conformal with skin, user's sense
Feel more comfortable, micropin is punctured without pain, not bleeding, can be healed rapidly using rear skin, securely and reliably.The facial mask uses micropin
The mode that array punctures, it is practical and convenient, it only need to gently clap, micropore transmission channel can be formed, beautifying nourishing ingredient is enabled to have
Effect penetrates into skin, and structure is simple, is easy to be mass produced.Obviously, the above embodiment of the present invention is only intended to clearly illustrate
Examples made by the present invention, rather than a limitation of the embodiments of the present invention.For those of ordinary skill in the art
For, other different forms of changes or modifications may be made based on the above description.There is no need and unable to institute
Some embodiments are exhaustive.Any modifications, equivalent replacements, and improvements done within the spirit and principles of the present invention
Deng should all be included in the scope of protection of the claims of the present invention.
Claims (6)
1. a kind of microneedle array elastic hydrogel facial mask, which is characterized in that including elastic hydrogel layer and microneedle array layer；It is described
Elastic hydrogel layer stores beautifying nourishing ingredient, and the elastic hydrogel layer includes elastic hydrogel；The microneedle array layer
Including microneedle array and flexible substrates；The microneedle array is fixed on the upper epidermis of the flexible substrates, the microneedle array from
The lower surface of the elastic hydrogel layer is inserted into the elastic hydrogel layer, and the upper epidermis of the flexible substrates and the bullet
The following table face contact of property hydrogel layer, the microneedle array does not penetrate the upper surface of the elastic hydrogel layer, if the elasticity
For hydrogel layer by compressive deformation, the micropin of the microneedle array penetrates the upper surface of the elastic hydrogel layer, is pierced into skin.
2. a kind of microneedle array elastic hydrogel facial mask according to claim 1, which is characterized in that the elastic hydrogel
1~2 millimeter of thickness of layer, the micropin height in the microneedle array are 500~1800 microns, and the spacing between adjacent micropin is
1 millimeter,
The microneedle array is inserted into the elastic hydrogel layer from the lower surface of the elastic hydrogel layer, and the flexible base
The following table face contact of the upper epidermis at bottom and the elastic hydrogel layer, the microneedle array do not penetrate the elastic hydrogel layer
Upper surface, specifically:
The microneedle array is inserted into the elastic hydrogel layer from the lower surface of the elastic hydrogel layer, and the flexible base
The following table face contact of the upper epidermis at bottom and the elastic hydrogel layer, the micropin top of the microneedle array and the elastic water-setting
The distance of the upper surface of glue-line is 200~500 microns.
3. a kind of microneedle array elastic hydrogel facial mask according to claim 1 or 2, it is characterised in that: the micropin battle array
Column are prepared using PLGA or PMMA or epoxy resin.
4. a kind of microneedle array elastic hydrogel facial mask according to claim 3, which is characterized in that the microneedle array knot
Structure is solid array of microneedles.
5. a kind of microneedle array elastic hydrogel facial mask according to claim 4, which is characterized in that the elastic hydrogel
Layer stores beautifying nourishing ingredient, specifically: the beautifying nourishing ingredient is evenly distributed in the elastic hydrogel.
6. a kind of microneedle array elastic hydrogel facial mask according to claim 5, which is characterized in that the flexible substrates
Material is latex or PVC or silk woven fabric or pure cotton fiber woven fabric.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811057107.4A CN109077938A (en) | 2018-09-11 | 2018-09-11 | A kind of microneedle array elastic hydrogel facial mask |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811057107.4A CN109077938A (en) | 2018-09-11 | 2018-09-11 | A kind of microneedle array elastic hydrogel facial mask |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN109077938A true CN109077938A (en) | 2018-12-25 |
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201811057107.4A Pending CN109077938A (en) | 2018-09-11 | 2018-09-11 | A kind of microneedle array elastic hydrogel facial mask |
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Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110935097A (en) * | 2019-12-03 | 2020-03-31 | 广州新济薇娜生物科技有限公司 | Microneedle patch for improving skin hypertrophic scar and preparation method thereof |
| CN110947088A (en) * | 2019-12-06 | 2020-04-03 | 广州新济薇娜生物科技有限公司 | Eye-protecting combined patch and preparation method thereof |
| WO2021073620A1 (en) | 2019-10-17 | 2021-04-22 | 上海萨美细胞技术有限公司 | Use of acellular adipose tissue extract in promoting hair growth and retention |
| WO2022098314A1 (en) * | 2020-11-09 | 2022-05-12 | National University Of Singapore | A multi-layered sheet mask |
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| CN106176572A (en) * | 2016-08-19 | 2016-12-07 | 中山大学 | A kind of microneedle array plaster and preparation method thereof |
| CN107073251A (en) * | 2014-11-14 | 2017-08-18 | 莱雅公司 | Micropin piece and forming method for reducing wrinkle |
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2018
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107073251A (en) * | 2014-11-14 | 2017-08-18 | 莱雅公司 | Micropin piece and forming method for reducing wrinkle |
| CN105997530A (en) * | 2016-07-11 | 2016-10-12 | 北京化工大学 | Combined micro-needle mask for removing wrinkles and dark circles |
| CN106176572A (en) * | 2016-08-19 | 2016-12-07 | 中山大学 | A kind of microneedle array plaster and preparation method thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2021073620A1 (en) | 2019-10-17 | 2021-04-22 | 上海萨美细胞技术有限公司 | Use of acellular adipose tissue extract in promoting hair growth and retention |
| CN110935097A (en) * | 2019-12-03 | 2020-03-31 | 广州新济薇娜生物科技有限公司 | Microneedle patch for improving skin hypertrophic scar and preparation method thereof |
| CN110935097B (en) * | 2019-12-03 | 2021-10-29 | 广州新济薇娜生物科技有限公司 | Microneedle patch for improving skin hypertrophic scar and preparation method thereof |
| CN110947088A (en) * | 2019-12-06 | 2020-04-03 | 广州新济薇娜生物科技有限公司 | Eye-protecting combined patch and preparation method thereof |
| WO2022098314A1 (en) * | 2020-11-09 | 2022-05-12 | National University Of Singapore | A multi-layered sheet mask |
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Application publication date: 20181225 |