CN109010763A - A kind of plaster for treating bone joint pain - Google Patents
A kind of plaster for treating bone joint pain Download PDFInfo
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- CN109010763A CN109010763A CN201811020766.0A CN201811020766A CN109010763A CN 109010763 A CN109010763 A CN 109010763A CN 201811020766 A CN201811020766 A CN 201811020766A CN 109010763 A CN109010763 A CN 109010763A
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- joint pain
- bone joint
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/11—Pteridophyta or Filicophyta (ferns)
- A61K36/12—Filicopsida or Pteridopsida
- A61K36/126—Drynaria
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/236—Ligusticum (licorice-root)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/47—Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/714—Aconitum (monkshood)
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
- A61K36/734—Crataegus (hawthorn)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/74—Rubiaceae (Madder family)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/85—Verbenaceae (Verbena family)
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- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9066—Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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Abstract
The invention discloses a kind of plaster for treating bone joint pain, including below according to the raw material of parts by weight: 10-18 parts of oenothera biennis extracting solution, 12-15 parts of monkshood, 5-11 parts of vomiting nut, 8-17 parts of radix achyranthis bidentatae, 8-10 parts of Radix Curcumae, 22-24 parts of bush, 21-26 parts of mountain Cape jasmine, 10-15 parts of safflower, 6-11 parts of rhizoma zingiberis, 22-27 parts of the rhizome of davallia, 6-8 parts of Caulis Spatholobi, 12-16 parts of Rhizoma Chuanxiong, 2-5 parts of the root of Dahurain angelica, 3-7 parts of bone grass, 10-17 parts of radix glycyrrhizae preparata, 21-26 parts of Flos Magnoliae Officinalis, 11-18 parts of fructus crataegi cuneatae, 10-19 parts of Verbena officinalis；The invention also discloses the preparation methods of the production method of the oenothera biennis extracting solution and the plaster of the treatment bone joint pain；The present invention has the middle medicinal substances of addition, and nonhazardous is without side-effects；To treatment arthralgia significant effect.
Description
Technical field
The present invention relates to tcm field, the plaster of specifically a kind for the treatment of bone joint pain.
Background technique
Significantly either student or staff all suffer from, osteoproliferation, disc herniation, cervical spondylosis etc. are asked
Topic, also faces this problem in the people of multiple age brackets, and many people need to be seated for a long time during study or work,
This just all brings very big load to vertebra and cervical vertebra, and long time integration leads to arthralgia.
For bone joint pain disease when there is no effect method, common plaster can only relieve pain the of short duration time, often
With conventional methods such as acupuncture-moxibustion, traction, physical therapies, treatment time is long, and curative effect is not shown.From traditional acupuncture, physical therapy, massage, lead hang to
Diskectomy, artificial intervertebral's displacement technique, the interverbebral disc in modern times, which are scraped, inhales a variety of methods such as art, and effect is not ideal enough, also has
Part drug for oral administration, as the saying goes " there's no such thing as a totally safe medicine ", side effect is larger, higher cost.
Therefore it proposes a kind of new low manufacture cost, while there are significant therapeutic effect and the low treatment Bones and joints of side effect
Ache plaster, to solve the above problems.
Summary of the invention
The purpose of the present invention is to provide a kind of plaster for treating bone joint pain, to solve to propose in above-mentioned background technique
The problem of.
To achieve the above object, the invention provides the following technical scheme:
A kind of plaster for treating bone joint pain, including below according to the raw material of parts by weight: oenothera biennis extracting solution 10-18
It is part, 12-15 parts of monkshood, 5-11 parts of vomiting nut, 8-17 parts of radix achyranthis bidentatae, 8-10 parts of Radix Curcumae, 22-24 parts of bush, 21-26 parts of mountain Cape jasmine, red
Flower 10-15 parts, 6-11 parts of rhizoma zingiberis, 22-27 parts of the rhizome of davallia, 6-8 parts of Caulis Spatholobi, 12-16 parts of Rhizoma Chuanxiong, 2-5 parts of the root of Dahurain angelica, bone grass 3-7
Part, 10-17 parts of radix glycyrrhizae preparata, 21-26 parts of Flos Magnoliae Officinalis, 11-18 parts of fructus crataegi cuneatae, 10-19 parts of Verbena officinalis.
As a further solution of the present invention: the preparation method of the Radix Oenotherae erythrosepalae extract, steps are as follows:
S1, oenothera biennis is weighed, impregnates 20-30min with warm water, wherein keeping water temperature is 35-40 DEG C, then filter moisture,
And the oenothera biennis after impregnating is put into extractor；
S2, the water for adding 150ml toward extractor, using resistance stove heating, water is burnt in the speed heating of 10 DEG C of heating per minute
It opens, then with being cooked by slow fire 1-1.5 hours；
S3, the ethanol solution that 30-40ml is added keep temperature in 40-45 DEG C, heat 30-40min, then filter, can obtain
Oenothera biennis aqueous extract.
As a further solution of the present invention: the preparation method of the plaster of the treatment bone joint pain, steps are as follows:
S11, monkshood, vomiting nut, radix achyranthis bidentatae, Radix Curcumae, bush, mountain Cape jasmine, safflower, rhizoma zingiberis, the rhizome of davallia, chicken are weighed according to parts by weight
Blood rattan, Rhizoma Chuanxiong, the root of Dahurain angelica, bone grass, radix glycyrrhizae preparata, Flos Magnoliae Officinalis, fructus crataegi cuneatae, Verbena officinalis, are separately dried, and use grinder powder after dry
It is broken, grinder model 30B-X, power of motor 15KW, discharging-material size 80-90mm；
S12, the mixture after grinding in S11 is placed in container, adds 2.5-3 times of weight water of mixed material, used
Electric heating stove heating, the rate of heat addition are 16-20 DEG C per minute, are heated to 65-75 DEG C of water temperature and keep the temperature, are stirred
It is even；
S13, oenothera biennis aqueous extract is added in the solution, continues to stir, be cooled to 10-15 DEG C after mixing, then
It is heated to the same rate of heat addition mutually synthermal, and stirs evenly, filter after mixing evenly, freezed after filter vacuum concentration dry
The dry plaster for obtaining treatment bone joint pain.
Compared with prior art, the beneficial effects of the present invention are:
1, the middle medicinal substances of present invention tool addition, nonhazardous are without side-effects；
2, the present invention is added to oenothera biennis extracting solution, and oenothera biennis has wind-damp dispelling, strengthening the bones and muscles, main wind-cold-dampness arthralgia, muscles and bones acid
The effects of soft, promoting blood circulation and removing obstruction in channels, suppressing the hyperactive liver to relieve the wind syndrome, healing up sore and subduing swelling, has good action to arthralgia；
3, the present invention also added Flos Magnoliae Officinalis, fructus crataegi cuneatae, Verbena officinalis, also have good effect to treatment arthralgia；
4, simply, conveniently, low manufacture cost is without side-effects to treatment arthralgia significant effect for manufacturing process of the present invention.
Specific embodiment
The technical scheme in the embodiments of the invention will be clearly and completely described below, it is clear that described implementation
Example is only a part of the embodiment of the present invention, instead of all the embodiments.Based on the embodiments of the present invention, this field is common
Technical staff's every other embodiment obtained without making creative work belongs to the model that the present invention protects
It encloses.
Embodiment 1
A kind of plaster for treating bone joint pain, including below according to the raw material of parts by weight: 10 parts of oenothera biennis extracting solution, river
Black 12 parts, 5 parts of vomiting nut, 8 parts of radix achyranthis bidentatae, 8 parts of Radix Curcumae, 22 parts of bush, 21 parts of mountain Cape jasmine, 10 parts of safflower, 6 parts of rhizoma zingiberis, the rhizome of davallia 22
Part, 6 parts of Caulis Spatholobi, 12 parts of Rhizoma Chuanxiong, 2 parts of the root of Dahurain angelica, bone careless 3 parts, 10 parts of radix glycyrrhizae preparata, 21 parts of Flos Magnoliae Officinalis, 11 parts of fructus crataegi cuneatae, Verbena officinalis
10 parts.
In the present embodiment, the preparation method of the Radix Oenotherae erythrosepalae extract, steps are as follows:
S1, oenothera biennis is weighed, impregnates 20min with warm water, wherein keeping water temperature is 35 DEG C, then filter moisture, and impregnate
Oenothera biennis afterwards is put into extractor；
S2, the water for adding 150ml toward extractor, using resistance stove heating, water is burnt in the speed heating of 10 DEG C of heating per minute
It opens, then with being cooked by slow fire 1 hour；
S3, the ethanol solution that 30ml is added keep temperature in 40 DEG C, heat 30min, then filter, can obtain oenothera biennis water
Extracting solution.
In the present embodiment, the preparation method of the plaster of the treatment bone joint pain, steps are as follows:
S11, monkshood, vomiting nut, radix achyranthis bidentatae, Radix Curcumae, bush, mountain Cape jasmine, safflower, rhizoma zingiberis, the rhizome of davallia, chicken are weighed according to parts by weight
Blood rattan, Rhizoma Chuanxiong, the root of Dahurain angelica, bone grass, radix glycyrrhizae preparata, Flos Magnoliae Officinalis, fructus crataegi cuneatae, Verbena officinalis, are separately dried, and use grinder powder after dry
It is broken, grinder model 30B-X, power of motor 15KW, discharging-material size 80mm；
S12, the mixture after grinding in S11 is placed in container, adds 2.5 times of weight waters of mixed material, uses electricity
Hot stove heating, the rate of heat addition are 16 DEG C per minute, are heated to 65 DEG C of water temperature and keep the temperature, are uniformly mixed；
S13, oenothera biennis aqueous extract is added in the solution, continues to stir, be cooled to 10 DEG C, then after mixing with same
The rate of heat addition of sample is heated to mutually synthermal, and stirs evenly, filters after mixing evenly, is freeze-dried and obtains after filter vacuum concentration
The plaster of bone joint pain must be treated.
Embodiment 2
A kind of plaster for treating bone joint pain, including below according to the raw material of parts by weight: 12 parts of oenothera biennis extracting solution, river
Black 13 parts, 7 parts of vomiting nut, 10 parts of radix achyranthis bidentatae, 9 parts of Radix Curcumae, 23 parts of bush, 23 parts of mountain Cape jasmine, 12 parts of safflower, 7 parts of rhizoma zingiberis, the rhizome of davallia 24
Part, 7 parts of Caulis Spatholobi, 13 parts of Rhizoma Chuanxiong, 3 parts of the root of Dahurain angelica, bone careless 4 parts, 12 parts of radix glycyrrhizae preparata, 22 parts of Flos Magnoliae Officinalis, 13 parts of fructus crataegi cuneatae, Verbena officinalis
13 parts.
In the present embodiment, the preparation method of the Radix Oenotherae erythrosepalae extract, steps are as follows:
S1, oenothera biennis is weighed, impregnates 22min with warm water, wherein keeping water temperature is 36 DEG C, then filter moisture, and impregnate
Oenothera biennis afterwards is put into extractor；
S2, the water for adding 150ml toward extractor, using resistance stove heating, water is burnt in the speed heating of 10 DEG C of heating per minute
It opens, then with being cooked by slow fire 1.2 hours；
S3, the ethanol solution that 33ml is added keep temperature in 42 DEG C, heat 33min, then filter, can obtain oenothera biennis water
Extracting solution.
In the present embodiment, the preparation method of the plaster of the treatment bone joint pain, steps are as follows:
S11, monkshood, vomiting nut, radix achyranthis bidentatae, Radix Curcumae, bush, mountain Cape jasmine, safflower, rhizoma zingiberis, the rhizome of davallia, chicken are weighed according to parts by weight
Blood rattan, Rhizoma Chuanxiong, the root of Dahurain angelica, bone grass, radix glycyrrhizae preparata, Flos Magnoliae Officinalis, fructus crataegi cuneatae, Verbena officinalis, are separately dried, and use grinder powder after dry
It is broken, grinder model 30B-X, power of motor 15KW, discharging-material size 85mm；
S12, the mixture after grinding in S11 is placed in container, adds 2.5 times of weight waters of mixed material, uses electricity
Hot stove heating, the rate of heat addition are 17 DEG C per minute, are heated to 67 DEG C of water temperature and keep the temperature, are uniformly mixed；
S13, oenothera biennis aqueous extract is added in the solution, continues to stir, be cooled to 12 DEG C, then after mixing with same
The rate of heat addition of sample is heated to mutually synthermal, and stirs evenly, filters after mixing evenly, is freeze-dried and obtains after filter vacuum concentration
The plaster of bone joint pain must be treated.
Embodiment 3
A kind of plaster for treating bone joint pain, including below according to the raw material of parts by weight: 15 parts of oenothera biennis extracting solution, river
Black 14 parts, 8 parts of vomiting nut, 14 parts of radix achyranthis bidentatae, 10 parts of Radix Curcumae, 24 parts of bush, 25 parts of mountain Cape jasmine, 14 parts of safflower, 9 parts of rhizoma zingiberis, the rhizome of davallia
25 parts, 8 parts of Caulis Spatholobi, 15 parts of Rhizoma Chuanxiong, 4 parts of the root of Dahurain angelica, bone careless 6 parts, 16 parts of radix glycyrrhizae preparata, 25 parts of Flos Magnoliae Officinalis, 17 parts of fructus crataegi cuneatae, horsewhip
17 parts of grass.
In the present embodiment, the preparation method of the Radix Oenotherae erythrosepalae extract, steps are as follows:
S1, oenothera biennis is weighed, impregnates 28min with warm water, wherein keeping water temperature is 37 DEG C, then filter moisture, and impregnate
Oenothera biennis afterwards is put into extractor；
S2, the water for adding 150ml toward extractor, using resistance stove heating, water is burnt in the speed heating of 10 DEG C of heating per minute
It opens, then with being cooked by slow fire 1.4 hours；
S3, the ethanol solution that 38ml is added keep temperature in 44 DEG C, heat 38min, then filter, can obtain oenothera biennis water
Extracting solution.
In the present embodiment, the preparation method of the plaster of the treatment bone joint pain, steps are as follows:
S11, monkshood, vomiting nut, radix achyranthis bidentatae, Radix Curcumae, bush, mountain Cape jasmine, safflower, rhizoma zingiberis, the rhizome of davallia, chicken are weighed according to parts by weight
Blood rattan, Rhizoma Chuanxiong, the root of Dahurain angelica, bone grass, radix glycyrrhizae preparata, Flos Magnoliae Officinalis, fructus crataegi cuneatae, Verbena officinalis, are separately dried, and use grinder powder after dry
It is broken, grinder model 30B-X, power of motor 15KW, discharging-material size 86mm；
S12, the mixture after grinding in S11 is placed in container, adds 2.8 times of weight waters of mixed material, uses electricity
Hot stove heating, the rate of heat addition are 18 DEG C per minute, are heated to 71 DEG C of water temperature and keep the temperature, are uniformly mixed；
S13, oenothera biennis aqueous extract is added in the solution, continues to stir, be cooled to 14 DEG C, then after mixing with same
The rate of heat addition of sample is heated to mutually synthermal, and stirs evenly, filters after mixing evenly, is freeze-dried and obtains after filter vacuum concentration
The plaster of bone joint pain must be treated.
Embodiment 4
A kind of plaster for treating bone joint pain, including below according to the raw material of parts by weight: 18 parts of oenothera biennis extracting solution, river
15 parts of crow, 11 parts of vomiting nut, 17 parts of radix achyranthis bidentatae, 10 parts of Radix Curcumae, 24 parts of bush, 26 parts of mountain Cape jasmine, 15 parts of safflower, 11 parts of rhizoma zingiberis, bone are broken
Mend 27 parts, 8 parts of Caulis Spatholobi, 16 parts of Rhizoma Chuanxiong, 5 parts of the root of Dahurain angelica, bone careless 7 parts, 17 parts of radix glycyrrhizae preparata, 26 parts of Flos Magnoliae Officinalis, 18 parts of fructus crataegi cuneatae, horse
19 parts of whip grass.
In the present embodiment, the preparation method of the Radix Oenotherae erythrosepalae extract, steps are as follows:
S1, oenothera biennis is weighed, impregnates 30min with warm water, wherein keeping water temperature is 40 DEG C, then filter moisture, and impregnate
Oenothera biennis afterwards is put into extractor；
S2, the water for adding 150ml toward extractor, using resistance stove heating, water is burnt in the speed heating of 10 DEG C of heating per minute
It opens, then with being cooked by slow fire 1.5 hours；
S3, the ethanol solution that 40ml is added keep temperature in 45 DEG C, heat 40min, then filter, can obtain oenothera biennis water
Extracting solution.
In the present embodiment, the preparation method of the plaster of the treatment bone joint pain, steps are as follows:
S11, monkshood, vomiting nut, radix achyranthis bidentatae, Radix Curcumae, bush, mountain Cape jasmine, safflower, rhizoma zingiberis, the rhizome of davallia, chicken are weighed according to parts by weight
Blood rattan, Rhizoma Chuanxiong, the root of Dahurain angelica, bone grass, radix glycyrrhizae preparata, Flos Magnoliae Officinalis, fructus crataegi cuneatae, Verbena officinalis, are separately dried, and use grinder powder after dry
It is broken, grinder model 30B-X, power of motor 15KW, discharging-material size 90mm；
S12, the mixture after grinding in S11 is placed in container, adds 3 times of weight waters of mixed material, uses electric heating
Stove heating, the rate of heat addition are 20 DEG C per minute, are heated to 75 DEG C of water temperature and keep the temperature, are uniformly mixed；
S13, oenothera biennis aqueous extract is added in the solution, continues to stir, be cooled to 15 DEG C, then after mixing with same
The rate of heat addition of sample is heated to mutually synthermal, and stirs evenly, filters after mixing evenly, is freeze-dried and obtains after filter vacuum concentration
The plaster of bone joint pain must be treated.
Comparative example 1
Comparative example 1 and the difference of embodiment 3 are, do not add Flos Magnoliae Officinalis, fructus crataegi cuneatae, remaining is the same as embodiment 3.
Comparative example 2
Comparative example 2 and the difference of embodiment 3 are, do not add oenothera biennis extracting solution, fructus crataegi cuneatae, remaining is the same as embodiment 3.
Comparative example 3
Comparative example 3 and the difference of embodiment 3 are, do not add oenothera biennis extracting solution, Flos Magnoliae Officinalis, remaining is the same as embodiment 3.
Comparative example 4
Comparative example 4 and the difference of embodiment 3 are, do not add oenothera biennis extracting solution, Flos Magnoliae Officinalis and fructus crataegi cuneatae, remaining is the same as real
Apply example 3.
The present invention, which further passes through clinical test and demonstrates pharmaceutical composition of the present invention, obtains therapeutic effect, using door in recent years
A large amount of clinical cases in examining are verified.
The clinical efficacy and safety of medicine composite for curing bronchitis of the present invention.
Case selection: the patient for the arthralgia conventionally made a definite diagnosis 220, male 110, women 110, year
Age is between 45-60, and job specification is similar, wherein gonalgia 30, lumbar pain 15, and cervical vertebra ache 15, shoulder joint
Section pain 20, elbow joint pain 20.
Wherein treatment group 100 are divided into tetra- groups of A, B, C, D, smear ointment made by 1-4 of the embodiment of the present invention, daily
Once in the morning and once at night, continue 10 days；
Control group totally 100, it is divided into tetra- groups of E, F, G, H, is wherein smeared made by comparative example 1-4 respectively for tetra- groups of E, F, G, H
Plaster once in the morning and once at night continue 10 days；
It reference group 20, smears the conventional plaster bought in the market and continues 15 days once a day；
Before smearing ointment, 220 arthralgia indexes are the detection in 17.56 ± 2.34 ranges, after 15 days
As a result following (being averaged):
By upper table it is found that having used plaster of the invention, pain index can be effectively relieved, compare and buy in the market
Conventional plaster, have better curative effect.
It is obvious to a person skilled in the art that invention is not limited to the details of the above exemplary embodiments, Er Qie
In the case where without departing substantially from spirit or essential attributes of the invention, the present invention can be realized in other specific forms.Therefore, no matter
From the point of view of which point, the present embodiments are to be considered as illustrative and not restrictive, and the scope of the present invention is by appended power
Benefit requires rather than above description limits, it is intended that all by what is fallen within the meaning and scope of the equivalent elements of the claims
Variation is included within the present invention.
In addition, it should be understood that although this specification is described in terms of embodiments, but not each embodiment is only wrapped
Containing an independent technical solution, this description of the specification is merely for the sake of clarity, and those skilled in the art should
It considers the specification as a whole, the technical solutions in the various embodiments may also be suitably combined, forms those skilled in the art
The other embodiments being understood that.
Claims (9)
1. a kind of plaster for treating bone joint pain, which is characterized in that including below according to the raw material of parts by weight: oenothera biennis is extracted
10-18 parts of liquid, 12-15 parts of monkshood, 5-11 parts of vomiting nut, 8-17 parts of radix achyranthis bidentatae, 8-10 parts of Radix Curcumae, 22-24 parts of bush, mountain Cape jasmine 21-
26 parts, 10-15 parts of safflower, 6-11 parts of rhizoma zingiberis, 22-27 parts of the rhizome of davallia, 6-8 parts of Caulis Spatholobi, 12-16 parts of Rhizoma Chuanxiong, 2-5 parts of the root of Dahurain angelica,
3-7 parts of bone grass, 10-17 parts of radix glycyrrhizae preparata, 21-26 parts of Flos Magnoliae Officinalis, 11-18 parts of fructus crataegi cuneatae, 10-19 parts of Verbena officinalis.
2. the plaster for the treatment of bone joint pain according to claim 1, which is characterized in that the system of the Radix Oenotherae erythrosepalae extract
Method is taken, steps are as follows:
S1, oenothera biennis is weighed, impregnates 20-30min with warm water, then filter moisture, and the oenothera biennis after immersion puts extractor into
In；
S2, the water for adding 150ml toward extractor, using resistance stove heating, the speed heating of 10 DEG C of heating per minute is boiled by water,
Again with being cooked by slow fire 1-1.5 hours；
S3, the ethanol solution that 30-40ml is added, heating, then filter, can obtain oenothera biennis aqueous extract.
3. the plaster for the treatment of bone joint pain according to claim 2, which is characterized in that in step S1, warm water temperature is
35-40℃。
4. it is according to claim 3 treatment bone joint pain plaster, which is characterized in that in step S3, keep temperature in
40-45 DEG C, heat 30-40min.
5. a kind of preparation method of the plaster of the treatment bone joint pain as described in claim 1-4 is any, which is characterized in that step
It is rapid as follows:
S11, monkshood, vomiting nut, radix achyranthis bidentatae, Radix Curcumae, bush, mountain Cape jasmine, safflower, rhizoma zingiberis, the rhizome of davallia, chicken blood are weighed according to parts by weight
Rattan, Rhizoma Chuanxiong, the root of Dahurain angelica, bone grass, radix glycyrrhizae preparata, Flos Magnoliae Officinalis, fructus crataegi cuneatae, Verbena officinalis, are separately dried, and are crushed after dry using grinder；
S12, the mixture after grinding in S11 is placed in container, adds 2.5-3 times of weight water of mixed material, uses electric heating
Stove heating is uniformly mixed；
S13, oenothera biennis aqueous extract is added in the solution, continues to stir, cools down after mixing, then similarly to heat speed
Rate is heated to mutually synthermal, and stirs evenly, filters after mixing evenly, freeze-drying obtains treatment bone and closes after filter vacuum concentration
Save the plaster of pain.
6. the preparation method of the plaster for the treatment of bone joint pain according to claim 5, which is characterized in that in step S11,
The grinder model 30B-X, power of motor 15KW, discharging-material size 80-90mm.
7. the preparation method of the plaster for the treatment of bone joint pain according to claim 6, which is characterized in that in step S12,
The rate of heat addition is 16-20 DEG C per minute, is heated to 65-75 DEG C of water temperature and keeps the temperature.
8. the preparation method of the plaster for the treatment of bone joint pain according to claim 7, which is characterized in that in step S13,
It is cooled to 10-15 DEG C.
9. purposes of the plaster in production treatment bone joint pain product as described in claim 1-4 is any.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811020766.0A CN109010763A (en) | 2018-09-03 | 2018-09-03 | A kind of plaster for treating bone joint pain |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201811020766.0A CN109010763A (en) | 2018-09-03 | 2018-09-03 | A kind of plaster for treating bone joint pain |
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| CN109010763A true CN109010763A (en) | 2018-12-18 |
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|---|---|---|---|---|
| CN1403139A (en) * | 2002-10-08 | 2003-03-19 | 李德邦 | Externally applied Chinese medicine for treating osteoarthropathy and its prepn process |
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| CN1403139A (en) * | 2002-10-08 | 2003-03-19 | 李德邦 | Externally applied Chinese medicine for treating osteoarthropathy and its prepn process |
| US20130052271A1 (en) * | 2011-08-29 | 2013-02-28 | Richard S. Sternasty | Compositions and Methods for Treating Pain |
| CN102872238A (en) * | 2012-09-06 | 2013-01-16 | 马加明 | Medicine for treating osteoarthrosis and preparation method thereof |
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Application publication date: 20181218 |