CN108990811B - Biological safety type independent ventilation cage - Google Patents

Biological safety type independent ventilation cage Download PDF

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Publication number
CN108990811B
CN108990811B CN201810958021.2A CN201810958021A CN108990811B CN 108990811 B CN108990811 B CN 108990811B CN 201810958021 A CN201810958021 A CN 201810958021A CN 108990811 B CN108990811 B CN 108990811B
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Prior art keywords
air
cage
exhaust
air supply
pipe
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CN201810958021.2A
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CN108990811A (en
Inventor
陈洪岩
陈明智
唐克
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SHENZHEN HONGTENG BIO-TECH Co.,Ltd.
Harbin Veterinary Research Institute of CAAS
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Shenzhen Hongteng Bio Tech Co ltd
Harbin Veterinary Research Institute of CAAS
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Priority to CN201810958021.2A priority Critical patent/CN108990811B/en
Publication of CN108990811A publication Critical patent/CN108990811A/en
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    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/02Pigsties; Dog-kennels; Rabbit-hutches or the like
    • A01K1/03Housing for domestic or laboratory animals
    • A01K1/031Cages for laboratory animals; Cages for measuring metabolism of animals
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/0047Air-conditioning, e.g. ventilation, of animal housings
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K1/00Housing animals; Equipment therefor
    • A01K1/0047Air-conditioning, e.g. ventilation, of animal housings
    • A01K1/0052Arrangement of fans or blowers
    • AHUMAN NECESSITIES
    • A01AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01KANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K31/00Housing birds
    • A01K31/002Poultry cages, e.g. transport boxes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/16Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor using chemical substances
    • A61L2/20Gaseous substances, e.g. vapours
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2/00Methods or apparatus for disinfecting or sterilising materials or objects other than foodstuffs or contact lenses; Accessories therefor
    • A61L2/26Accessories or devices or components used for biocidal treatment
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D35/00Filtering devices having features not specifically covered by groups B01D24/00 - B01D33/00, or for applications not specifically covered by groups B01D24/00 - B01D33/00; Auxiliary devices for filtration; Filter housing constructions
    • B01D35/14Safety devices specially adapted for filtration; Devices for indicating clogging
    • B01D35/153Anti-leakage or anti-return valves
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2202/00Aspects relating to methods or apparatus for disinfecting or sterilising materials or objects
    • A61L2202/10Apparatus features
    • A61L2202/12Apparatus for isolating biocidal substances from the environment
    • A61L2202/121Sealings, e.g. doors, covers, valves, sluices

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  • Life Sciences & Earth Sciences (AREA)
  • Environmental Sciences (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Animal Husbandry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Birds (AREA)
  • General Chemical & Material Sciences (AREA)
  • Clinical Laboratory Science (AREA)
  • Ventilation (AREA)

Abstract

The invention discloses a biosafety type independent ventilation cage which comprises a control host, a cage frame and a cage box, wherein an air supply duct is arranged in the control host, the air exhaust device comprises an air exhaust duct and an exhaust fan, wherein the input end of the air exhaust duct is communicated with the outside, the output end of the air exhaust duct is hermetically connected with a cage main air supply pipe, the air supply outlet of the cage main air supply pipe is hermetically connected with a cage box air supply nozzle, the input end of the air exhaust duct is hermetically connected with a cage main exhaust pipe, the air exhaust outlet of the cage main exhaust pipe is hermetically connected with a cage box exhaust nozzle, the output end of the air exhaust duct is communicated with the outside, an exhaust outlet of the air exhaust duct is provided with the exhaust fan, an air supply primary filter device, a first stop valve and an air supply high-efficiency filter device are sequentially arranged in the air exhaust duct, an air exhaust high-efficiency filter device and a second stop valve are sequentially arranged in the air exhaust duct, and the air exhaust duct is respectively connected with an external fumigation type sterilizer through a disinfection air inlet pipe and a disinfection exhaust pipe. The invention can provide animal experiment environment required by the national third level of biological safety.

Description

Biological safety type independent ventilation cage
Technical Field
The invention relates to the technical field of animal experiment equipment products, in particular to a biosafety type independent ventilation cage.
Background
The prior art has the following defects: 1. the air supply and exhaust pipeline connected among the traditional IVC host, the cage frame and the cage box is internally provided with a high-efficiency filter, but the high-efficiency filter has no sealing disinfection and sterilization function, and if disinfection and sterilization are carried out after the high-efficiency filter is detached, the high-efficiency filter is more or less polluted by environment when being assembled, and workers can easily infect each other in the process of cleaning parts infected by high-risk viruses in the mode, so that the authenticity of virus experiments is influenced, and meanwhile, the life safety of operators is seriously threatened.
2. Conventional IVCs have poor reliability with respect to gas seal tightness and internal gas leak prevention problems.
3. After the cage box is taken down from the cage frame, the cage box can not maintain a continuous negative pressure barrier, which brings inconvenience to the cage changing or transferring operation of animals with specific pathogen bodies in the cage.
The above problems determine that the traditional IVC can not provide the animal experiment environment required by the third level of national biosafety.
Disclosure of Invention
The invention aims to overcome the defects of the prior art and provide a biosafety type independent ventilation cage suitable for biosafety three levels.
The technical scheme of the invention is as follows: a biosafety type independent ventilation cage comprises a control host, a cage and a cage box, wherein an air supply duct, an air exhaust duct and an exhaust fan are arranged in the control host, the input end of the air supply duct is communicated with the outside, the output end of the air supply duct is hermetically connected with a main air supply pipe of the cage, the air supply outlet of the main air supply pipe of the cage is hermetically connected with an air supply nozzle of the cage box, the input end of the air exhaust duct is hermetically connected with a main exhaust pipe of the cage, the exhaust outlet of the main exhaust pipe of the cage is hermetically connected with an exhaust nozzle of the cage box, the output end of the air exhaust duct is communicated with the outside, the exhaust outlet of the air exhaust duct is provided with the exhaust fan, an air supply primary filter device, a first stop valve and an air supply high-efficiency filter device are sequentially arranged in the air supply duct along the direction of the wind direction, the first stop valve is connected with the air supply primary filter device to control the opening and closing of the air supply primary filter device, the utility model discloses a high-efficient filter equipment of airing exhaust, including first stop valve, second stop valve, and fumigation formula sterilizer air inlet, the direction of airing exhaust along the wind direction has set gradually high-efficient filter equipment of airing exhaust and second stop valve in the wind channel of airing exhaust, the second stop valve is connected the high-efficient filter equipment of airing exhaust control its switching, the wind channel of airing exhaust is connected with outside fumigation formula sterilizer through disinfection intake pipe and disinfection blast pipe respectively, fumigation formula sterilizer air inlet is connected to the one end of disinfection intake pipe, the other end of disinfection intake pipe is connected through the third stop valve between first stop valve and the high-efficient filter equipment of airing exhaust, the one end of disinfection blast pipe is passed through the fourth stop valve and is connected between second stop valve and the high-efficient filter equipment of airing exhaust, fumigation formula sterilizer gas vent is connected to the other end of disinfection blast pipe.
Furthermore, air supply high efficiency filter equipment with be provided with first leak hunting device between the cage owner blast pipe, cage owner blast pipe with be provided with second leak hunting device between the high efficiency filter equipment of airing exhaust, the second stop valve with be provided with third leak hunting device between the exhaust fan.
Furthermore, the biological safety type independent ventilation cage can act on a plurality of cage boxes simultaneously, a plurality of air supply branch pipes are distributed on the main air supply pipe of the cage frame in a shunting manner, one ends of the air supply branch pipes are connected with the main air supply pipe of the cage frame in a sealing manner, the other ends of the air supply branch pipes are connected with the air supply nozzles of the cage boxes in a sealing manner, a plurality of air exhaust branch pipes are distributed on the main exhaust pipe of the cage frame in a shunting manner, one ends of the air exhaust branch pipes are connected with the main exhaust pipe of the cage frame in a sealing manner, and the other ends of the air exhaust branch pipes are connected with the exhaust nozzles of the cage boxes of the corresponding cage boxes in a sealing manner.
Furthermore, the other end of the air supply branch pipe can be simultaneously connected with the cage box air supply nozzles of a plurality of cage boxes, correspondingly, the other end of the air exhaust branch pipe can be simultaneously connected with the cage box air exhaust nozzles of a plurality of corresponding cage boxes.
Furthermore, the cage main air supply pipe and the cage main exhaust pipe are respectively in sealing connection with the air supply branch pipe and the air exhaust branch pipe through silica gel connectors on the cage main air supply pipe and the cage main exhaust pipe.
Furthermore, the other ends of the air supply branch pipe and the air exhaust branch pipe are respectively provided with a self-closing air nozzle with elastic reset seal, and the cage box air supply nozzle and the cage box air exhaust nozzle are in sealed connection through the self-closing air nozzles.
Furthermore, the output end of the air supply duct is hermetically connected with the main air supply pipe of the cage frame, and the input end of the air exhaust duct is hermetically connected with the main exhaust pipe of the cage frame through flanges.
Further, the exhaust fan is equipped with two and is located the exhaust pipe of difference respectively, and each exhaust fan is connected with an electric butterfly valve, through electric butterfly valve control exhaust fan's switching, two exhaust fans pass through its work in turn of control module control.
Furthermore, an air speed sensor, a pressure sensor and a temperature and humidity sensor are also arranged at the output end of the air exhaust duct.
Further, the control host is provided with an online UPS power supply.
Compared with the prior art, the invention has the beneficial effects that: 1. the design of the invention ensures that the whole air supply and exhaust duct completes sealed disinfection, ensures that the disinfected rut bottom can not be infected before use, simultaneously avoids the possibility of mutual infection caused by manual contact disinfection, ensures the life to be guaranteed, and can ensure that each electronic part is not influenced by the disinfectant and the function and the service life of each electronic part; 2. the multi-point leak detection device detects the high-efficiency filter and ensures that the high-efficiency filter operates under the condition of no leakage; 3. the cage frame air supply and exhaust self-closing ensures that the system can still stably operate when part of cage boxes are taken down; 4. the cage box belt can filter efficiently to prevent the exhaust leakage from causing infection; 5. the air inlet and outlet nozzle of the cage frame and the cage box are connected with a double-layer sealing structure to provide various guarantees for connection leakage; 6. the single fan operates, active air exhaust and passive air supply are carried out, and negative pressure operation in the cage is ensured.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed for the embodiments or the prior art descriptions will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
FIG. 1 is a system block diagram of a biosafety independent ventilation cage according to the present invention;
FIG. 2 is a schematic view of the connection between the main supply air pipe and the branch supply air pipe of the cage according to the present invention;
FIG. 3 is a schematic view of the connection between the main exhaust duct and the exhaust branch duct of the cage according to the present invention;
fig. 4 is a schematic structural view of the cage of the present invention.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention more apparent, the present invention will be described in further detail with reference to the accompanying drawings and embodiments. It should be understood that the specific embodiments described herein are merely illustrative of the invention and are not intended to limit the invention.
In order to explain the technical means of the present invention, the following description will be given by way of specific examples.
Examples
Referring to fig. 1, the embodiment provides a biosafety type independent ventilation cage suitable for biosafety at three levels, which comprises a control host, a cage frame and cage boxes, wherein the biosafety type independent ventilation cage can act on a plurality of cage boxes simultaneously, and a plurality of sealable areas are arranged in the control host to form an air supply duct and an air exhaust duct; the air supply device comprises an air supply air duct, a cage main air supply pipe, a plurality of air supply branch pipes, a plurality of cage box air supply nozzles and a plurality of air supply branch pipes, wherein the input end of the air supply air duct is communicated to the outside to extract outside air, the output end of the air supply air duct is hermetically connected with the cage main air supply pipe, the cage main air supply pipe is divided into a plurality of air supply branch pipes, one end of each air supply branch pipe is hermetically connected with the cage main air supply pipe, and the other end of each air supply branch pipe is hermetically connected with the cage box air supply nozzles of a plurality of cage boxes; the input end of the air exhaust duct is hermetically connected with the cage main exhaust duct, a plurality of air exhaust branch pipes are distributed on the cage main exhaust duct, one end of each air exhaust branch pipe is hermetically connected with the cage main exhaust duct, the other end of each air exhaust branch pipe can be hermetically connected with a plurality of cage box exhaust nozzles corresponding to the cage boxes, and the output end of the air exhaust duct is communicated to the outside; an exhaust fan is arranged at an exhaust outlet of the exhaust air duct, air is extracted through rotation of the exhaust fan and enters the air supply duct, a single fan is adopted for operation, and active exhaust and passive air supply are performed to ensure negative pressure operation in the cage.
The direction along the wind direction has set gradually air supply primary filter equipment, first stop valve and air supply high efficiency filter equipment in the air supply wind channel, the air supply primary filter is installed and is carried out the prefilter in the air supply wind channel outside to the air that comes in, and its switching of air supply primary filter equipment control is connected to first stop valve, air supply high efficiency filter equipment carries out filtration treatment to the air that comes in, and the air supply wind channel is connected with outside stifling formula sterilizer through the disinfection intake pipe, and stifling formula sterilizer air inlet is connected to the one end of disinfection intake pipe, and the other end of disinfection intake pipe passes through the third stop valve and connects between first stop valve and air supply high efficiency filter equipment. And closing the first stop valve during disinfection, isolating and preventing disinfection leakage, opening the third stop valve, opening the first stop valve during work to be communicated with the air supply primary filter, and closing the third stop valve, wherein the first stop valve and the third stop valve have electric and manual modes.
The air is filtered by the primary air supply filter device and the high-efficiency air supply filter device, then is sent to the main air supply pipe of the cage frame and then is distributed to the air supply branch pipes, enters the cage box connected with the air supply nozzle through the cage box air supply nozzle, and the waste gas in the cage box is filtered by the high-efficiency air exhaust filter device in the cage box under the action of the exhaust fan and then is exhausted to the exhaust branch pipes of the cage frame and the main exhaust pipe of the cage frame through the exhaust nozzle of the cage box and then flows into the exhaust air duct of the control host.
The direction along the wind direction has set gradually high-efficient filter equipment and the second stop valve of airing exhaust in the wind channel of airing exhaust, the high-efficient filter equipment of airing exhaust carries out filtration treatment to the air of discharging, its switching of the high-efficient filter equipment control of airing exhaust is connected to the second stop valve, the wind channel of airing exhaust is connected with outside stifling formula steriliser through the disinfection blast pipe, the one end of disinfection blast pipe is passed through the fourth stop valve and is connected between second stop valve and the high-efficient filter equipment of airing exhaust, stifling formula steriliser gas vent is connected to the other end of disinfection blast pipe. The fourth stop valve is opened when the disinfection, and the during operation is closed, and the second stop valve closes the interior electronic components of protection host computer when the disinfection, and the during operation is opened, second stop valve and fourth stop valve have electronic and manual mode.
Wind speed sensor, pressure sensor, temperature and humidity sensor and two exhaust fans are connected to the output in the wind channel of airing exhaust after that, two exhaust fans are located the exhaust pipe of difference respectively, and each exhaust fan is connected with an electric butterfly valve, two exhaust fans control its work in turn through control module and in order to prolong the fan life-span, and two exhaust fans respectively join in marriage an electric butterfly valve, and the exhaust fan of work corresponds electric butterfly valve and opens, and the exhaust fan of inoperative corresponds electric butterfly valve and closes, and the exhaust fan is discharged the internal gas to the external world through exhaust pipe at last.
In addition, the control host is provided with an online UPS power supply. The power is cut off for 0 second, and the work is continued for more than 2 hours after the power is cut off.
In this embodiment, be provided with first leak hunting device between air supply high efficiency filter equipment and cage owner blast pipe, be provided with second leak hunting device between cage owner exhaust column and the high efficiency filter equipment of airing exhaust, be provided with third leak hunting device between second stop valve and the exhaust fan. Can be used for checking whether the cleanliness of the gas flowing through the device meets the requirement. Ensures that the filtration process operates under leak-free conditions.
The output end of the air supply duct is connected with the main air supply pipe of the cage frame, and the input end of the air exhaust duct is connected with the main exhaust pipe of the cage frame through flanges in a sealing way. The connecting flange is convenient, quick and reliable to connect.
As shown in fig. 2 and 3, the cage main air supply pipe 1 and the cage main exhaust pipe 2 are respectively connected with the air supply branch pipe 4 and the exhaust branch pipe 5 in a sealing way through the silica gel connectors 3 on the cage main air supply pipe and the cage main exhaust pipe. The other ends of the air supply branch pipe 4 and the air exhaust branch pipe 5 are respectively provided with a self-closing air nozzle 6 with elastic reset seal, and the cage box air supply nozzle and the cage box air exhaust nozzle are connected in a sealing way through the self-closing air nozzles 6. When the cage box is installed, the self-closing air faucet 6 opens the air circulation, when the cage box is taken down, the self-closing air faucet can be automatically closed to prevent external air from directly entering, the exhaust leakage is prevented from causing infection, the system can also stably operate when partial cage box is taken down, the self-closing air faucet 6 has a double-layer sealing function, and multiple guarantees are provided for connection leakage.
As shown in fig. 4, the cage box is an internally sealed animal living area composed of an upper cover 71, a cage box sealing ring, a bottom cage 72 and a multi-point buckle safety switch device 73, and the cage box is provided with a cage box air supply nozzle 74 and a cage box air exhaust nozzle 75 which are communicated with the inside. The multi-point buckle safety switch device 73 ensures that the sealing performance of the pressure in the cage is not less than 5 seconds from-100 Pa to-0 Pa, and air in the cage is replaced through the cage air supply nozzle 74 and the cage air exhaust nozzle 75.
In conclusion, the invention ensures that the whole air supply and exhaust duct completes sealed disinfection, ensures that the disinfected rut bottom does not have infection before use, avoids the possibility of mutual infection caused by manual contact disinfection, ensures the life and can ensure that each electronic part has no influence on the function and the service life of the disinfection solution. The animal experiment environment required by the national third level of biosafety is met.
The above description is only exemplary of the present invention and should not be taken as limiting the invention, as any modification, equivalent replacement, or improvement made within the spirit and principle of the present invention should be included in the protection scope of the present invention.

Claims (1)

1. The utility model provides a biological safety type independent ventilation cage utensil, comprises main control system, cage box, be equipped with air supply duct, air exhaust duct and exhaust fan in the main control system, the input in air supply duct communicates the outside, air supply duct's output and cage main supply-air pipe sealing connection, the supply-air outlet and the cage box air supply nozzle sealing connection of cage main supply-air pipe, the input and the cage main exhaust duct sealing connection in air exhaust duct, the air exit and the cage box exhaust nozzle sealing connection of cage main exhaust duct, the output in air exhaust duct communicates the outside, air exhaust duct's air exit is provided with the exhaust fan, its characterized in that: an air supply primary filter device, a first stop valve and an air supply high-efficiency filter device are sequentially arranged in the air supply duct along the direction of the wind direction, the first stop valve is connected with the air supply primary filter device to control the opening and closing of the air supply primary filter device, an air exhaust high-efficiency filter device and a second stop valve are sequentially arranged in the air exhaust duct along the direction of the wind direction, the second stop valve is connected with the air exhaust high-efficiency filter device to control the opening and closing of the air exhaust high-efficiency filter device, the air supply duct and the air exhaust duct are respectively connected with an external fumigation type sterilizer through a disinfection air inlet pipe and a disinfection exhaust pipe, one end of the disinfection air inlet pipe is connected with an air inlet of the fumigation type sterilizer, the other end of the disinfection air inlet pipe is connected between the first stop valve and the air supply high-efficiency filter device through a third stop valve, and one end of the disinfection exhaust pipe is connected between the second stop valve and the air exhaust high-efficiency filter device through a fourth stop valve, the other end of the disinfection exhaust pipe is connected with an exhaust port of the fumigation type sterilizer; the exhaust fans are provided with two exhaust air channels which are respectively positioned in different exhaust air channels, each exhaust fan is connected with an electric butterfly valve, the opening and closing of the exhaust fans are controlled by the electric butterfly valves, and the two exhaust fans are controlled by the control module to alternately work; the output end of the air exhaust duct is also provided with an air speed sensor, a pressure sensor and a temperature and humidity sensor; the fourth stop valve is opened during disinfection and closed during work, the second stop valve is closed during disinfection, electronic parts in the control host are protected, and the fourth stop valve is opened during work;
a first leak detection device is arranged between the air supply efficient filtering device and the cage frame main air supply pipe, a second leak detection device is arranged between the cage frame main exhaust pipe and the exhaust efficient filtering device, and a third leak detection device is arranged between the second stop valve and the exhaust fan;
the biological safety type independent ventilation cage simultaneously acts on a plurality of cage boxes, a plurality of air supply branch pipes are distributed on a main air supply pipe of the cage frame in a shunting manner, one ends of the air supply branch pipes are hermetically connected with the main air supply pipe of the cage frame, the other ends of the air supply branch pipes are hermetically connected with an air supply nozzle of the cage box, a plurality of air exhaust branch pipes are distributed on a main exhaust pipe of the cage frame in a shunting manner, one ends of the air exhaust branch pipes are hermetically connected with the main exhaust pipe of the cage frame, and the other ends of the air exhaust branch pipes are hermetically connected with exhaust nozzles of the cage boxes of the corresponding cage boxes;
the other end of the air supply branch pipe is simultaneously connected with the cage box air supply nozzles of a plurality of cage boxes, and correspondingly, the other end of the air exhaust branch pipe is simultaneously connected with the cage box exhaust nozzles of a plurality of corresponding cage boxes;
the cage main air supply pipe and the cage main exhaust pipe are respectively connected with the air supply branch pipe and the exhaust branch pipe in a sealing way through silica gel connectors on the cage main air supply pipe and the cage main exhaust pipe;
the other ends of the air supply branch pipe and the air exhaust branch pipe are respectively provided with a self-closing air nozzle with elastic reset seal, and the cage box air supply nozzle and the cage box air exhaust nozzle are in sealed connection through the self-closing air nozzles;
the output end of the air supply duct is hermetically connected with the main air supply pipe of the cage frame, and the input end of the air exhaust duct is hermetically connected with the main air exhaust pipe of the cage frame through flanges;
the cage box is an internally sealed animal living area consisting of an upper cover, a cage box sealing ring, a bottom cage and a multi-point buckle safety switch device, and is provided with a cage box air supply nozzle and a cage box exhaust nozzle which are communicated with the inside; the multi-point buckle safety switch device ensures that the time from-100 Pa to-0 Pa of the sealing pressure in the cage is not less than 5 seconds, and the air in the cage is replaced by the cage air supply nozzle and the cage exhaust nozzle;
the control host is provided with an online UPS power supply.
CN201810958021.2A 2018-08-22 2018-08-22 Biological safety type independent ventilation cage Active CN108990811B (en)

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CN109906947B (en) * 2019-04-03 2023-07-18 苏州市冯氏实验动物设备有限公司 Main unit of IVC experimental animal box, IVC experimental animal box and IVC experimental animal box method
CN109906948B (en) * 2019-04-03 2023-07-18 苏州市冯氏实验动物设备有限公司 Air internal circulation system of IVC experimental animal box and control method
CN113115711A (en) * 2021-04-23 2021-07-16 温氏食品集团股份有限公司 Integrated building pig farm for pig breeding
CN115119759B (en) * 2022-05-24 2023-05-30 温州医科大学 Independent ventilation sealing cage
CN117906864B (en) * 2024-03-19 2024-05-28 盐城市计量测试所 Leakage detection system and detection method for independent ventilation cage

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