CN215291660U - PCR biological safety detection cabin - Google Patents
PCR biological safety detection cabin Download PDFInfo
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- CN215291660U CN215291660U CN202022508445.4U CN202022508445U CN215291660U CN 215291660 U CN215291660 U CN 215291660U CN 202022508445 U CN202022508445 U CN 202022508445U CN 215291660 U CN215291660 U CN 215291660U
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Abstract
The utility model discloses a PCR biological safety detection cabin, the main structure of which is a container, the interior of which is divided into four independent areas, a reagent preparation area, a sample preparation amplification analysis area, a ventilation and filtration system room area and a control system room area in turn; the reagent preparation area is communicated with the sample preparation amplification analysis area through a transfer window; the reagent preparation area and the sample preparation amplification analysis area are used as independent inner core spaces, a pipeline interlayer is arranged between the top of the reagent preparation area and the outer box body, and the ventilation and filtration system is respectively connected with the reagent preparation area and the sample preparation amplification analysis area through pipelines of the interlayer; the reagent preparation chamber area comprises a preparation buffer chamber and a reagent preparation chamber which are communicated through a first sealing door; the sample preparation amplification analysis area comprises an analysis buffer chamber and a sample preparation amplification analysis chamber which are communicated through a second sealing door. The beneficial effects of the utility model are that remove nimble, quick reaction, safe and reliable, economical and practical.
Description
Technical Field
The utility model relates to a biological laboratory technical field especially relates to a PCR biological safety detection cabin.
Background
The infectious diseases, especially respiratory infectious diseases, have the characteristics of strong infectivity, high transmission speed, wide infection range and the like. In the infectious disease prevention and control fight, the principles of early discovery, early isolation, early diagnosis and early treatment need to be adhered to, and whether citizens with suspected symptoms can diagnose, isolate and treat in time becomes one of the focuses of epidemic prevention work.
At present, laboratories suitable for the biosafety levels of P2 and P2+ are generally arranged in hospitals or laboratories, are non-mobile devices, and when serious sudden infectious diseases occur, dangerous samples need to be transported to corresponding laboratories for detection, so that the transportation safety and the detection rapidity cannot be guaranteed.
SUMMERY OF THE UTILITY MODEL
The utility model provides a PCR biological safety detection cabin has and removes outstanding characteristics such as nimble, quick reaction, safe and reliable, economical and practical, can be when great sudden infectious disease takes place, and open into the epidemic area immediately and detect the virus, need not make dangerous sample and transport midway again, guarantees simultaneously that all biological pollutants discharge safely inclusively.
The utility model provides a specific technical scheme as follows:
a PCR biological safety detection cabin has a main structure of a container, the interior of the container is divided into four independent areas, namely a reagent preparation area, a sample preparation amplification analysis area, a ventilation and filtration system area and a control system area;
the reagent preparation area is communicated with the sample preparation amplification analysis area through a transfer window; the reagent preparation area and the sample preparation amplification analysis area are used as independent inner core spaces, and a pipeline interlayer is arranged between the top of the reagent preparation area and the outer box body;
the ventilation and filtration system of the ventilation and filtration system area is respectively connected with the reagent preparation area and the sample preparation amplification analysis area through pipelines arranged in the interlayer; the power distribution and control system of the control system area is connected with the reagent preparation area and the sample preparation amplification analysis area through a pipeline interlayer;
the reagent preparation area comprises a preparation buffer chamber and a reagent preparation chamber which are communicated through a first sealing door;
the sample preparation amplification analysis area comprises an analysis buffer chamber and a sample preparation amplification analysis chamber which are communicated through a second sealing door.
In the scheme, a plane design of two partitions is adopted, namely an experimental region and an analysis region are independently arranged, and an independent buffer region is arranged in the experimental region and the analysis region; on one hand, air exchange between effective blocking areas is realized, and on the other hand, indoor pressure difference is ensured; the two areas are communicated through the transfer window, the transfer window is an electronic interlocking window, and the inside of the transfer window is provided with the ultraviolet sterilization device, so that cross contamination caused by air circulation between the areas can be effectively avoided. Optionally, the ventilation and filtration system includes an exhaust device and a fresh air device, and the fresh air device is respectively conveyed to each chamber through a pipeline in the pipeline interlayer; the exhaust device is connected with the exhaust outlets of all the chambers through exhaust branch pipes, the exhaust outlets are arranged below all the chambers, and the exhaust outlets of the sample preparation amplification analysis chamber are connected with the high-efficiency filter. In the technical scheme, an air supply and exhaust mode of upper air supply and lower air discharge is adopted, so that the stability of indoor airflow is ensured.
Optionally, the analysis buffer chamber comprises a hand washing sink, a wardrobe and a shoe cover cabinet, and the pressure in the chamber is-10 Pa; the sample preparation amplification analysis chamber comprises a full-automatic nucleic acid purification and fluorescence PCR analysis system and a pressure steam sterilization pot, and the pressure in the chamber is-20 Pa. In the technical improvement, the step design of the air pressure can ensure that harmful gas generated indoors does not overflow, and in addition, the pressure steam sterilization pot is used for sterilizing and disinfecting wastes.
Optionally, the preparation buffer chamber comprises a hand washing sink, a wardrobe and a shoe cover cabinet, and the pressure in the preparation buffer chamber is +10 Pa; the reagent preparation chamber comprises a workbench and a test bed, and the pressure in the chamber is +20 Pa.
Optionally, ultraviolet germicidal lamps are arranged in the sample preparation, amplification and analysis area and the reagent preparation area, and the ultraviolet germicidal lamps are controlled by the control system room. In the technical improvement, the indoor air is sterilized by the ultraviolet sterilizing lamp.
Optionally, the fresh air device adopts a direct expansion type air conditioning unit, and the functional section of the fresh air device sequentially comprises an electric preheating section, a primary effect filtering section, a medium effect filtering section I, a direct expansion section, an electric heating section, an air blower section, a flow equalizing section, a medium effect filtering section II, a humidifying section and an air blowing section; the fresh air inlet of each chamber adopts a shutter air port for preventing insects and rain.
Optionally, the exhaust device includes one and one spare two exhaust fans, and the exhaust fans are all provided with check valves.
The utility model has the advantages that: the system has the outstanding characteristics of flexible movement, quick response, safety, reliability, economy, practicality and the like, can be immediately sent to an epidemic area to detect viruses when major sudden infectious diseases occur, does not need to transport dangerous samples midway, and simultaneously ensures that all biological pollutants are safely and hermetically discharged.
Drawings
In order to more clearly illustrate the technical solutions in the embodiments of the present invention, the drawings needed to be used in the description of the embodiments will be briefly described below, and it is obvious that the drawings in the following description are only some embodiments of the present invention, and it is obvious for those skilled in the art to obtain other drawings without creative efforts.
Fig. 1 is a schematic top perspective view of an embodiment of the present invention;
fig. 2 is a schematic front structural view of an embodiment of the present invention;
fig. 3 is a top view structural diagram of an air exhaust device and a fresh air device according to an embodiment of the present invention;
fig. 4 is a front view structural diagram of a fresh air device according to an embodiment of the present invention;
fig. 5 is a front view structural diagram of an air exhaust device according to an embodiment of the present invention;
fig. 6 is a cross-sectional view at a-a of fig. 4 according to an embodiment of the present invention;
fig. 7 is a cross-sectional view at B-B of fig. 4 in accordance with an embodiment of the present invention;
fig. 8 is a front view of a fresh air handling unit according to an embodiment of the present invention.
In the figure, 1, a reagent preparation chamber; 2. preparing a buffer chamber; 3. a sample preparation amplification analysis chamber; 4. an analysis buffer chamber; 5. a pass-through window; 8. a control system room; 9. a pipe interlayer; 21. A hand sink I; 41. a hand sink II; 22. a wardrobe I; 42. a wardrobe II; 23. a shoe cover cabinet I; 43. a shoe cover cabinet II; 24. a first sealing door; 44. a second sealing door; 31. a full-automatic nucleic acid purification and fluorescence PCR analysis system; 32. a pressure steam sterilization pot; 33. a high efficiency filter; 45. a fresh air handling unit; 46. a fresh air taking pipe; 47. a fresh air main air pipe; 48. A fresh air branch pipe; 49. a fresh air electric air volume adjusting valve; 50. a fresh air port; 51. an electric preheating section; 52. a primary filtering section 53 and a medium-efficiency filtering section I; 53', intermediate filtering II section; 54. A direct expansion section; 55. an electrical heating section; 56. a blower section; 57. a flow equalization section 58, a humidification section; 59. an air supply section; 60. soft connection; 61. a micropore air supply outlet; 62. an air outlet; 63. An exhaust branch pipe; 64. a main exhaust pipe; 65. a first air exhaust static pressure box; 66. a check valve; 67. An exhaust fan; 68. a second air exhaust static pressure box; 69. and an exhaust outlet.
Detailed Description
In order to make the objects, technical solutions and advantages of the present invention clearer, the present invention will be described in further detail with reference to the accompanying drawings, and it is obvious that the described embodiments are only some embodiments of the present invention, not all embodiments. Based on the embodiments in the present invention, all other embodiments obtained by a person skilled in the art without creative efforts belong to the protection scope of the present invention.
A PCR biosafety test chamber according to an embodiment of the present invention will be described in detail with reference to FIGS. 1 to 2.
Referring to fig. 1 and 2, a PCR biosafety detection chamber has a main structure of a container, which divides the interior of the container into four independent areas, namely a reagent preparation area, a sample preparation amplification analysis area, a ventilation and filtration system area and a control system area; the reagent preparation area is communicated with the sample preparation amplification analysis area through a transfer window 5; the reagent preparation area and the sample preparation amplification analysis area are used as independent inner core spaces, a pipeline interlayer 9 is arranged between the top of the reagent preparation area and the outer box body, and the ventilation and filtration system is respectively connected with the reagent preparation area and the sample preparation amplification analysis area through pipelines arranged in the interlayer;
the reagent preparation area comprises a preparation buffer chamber 2 and a reagent preparation chamber 1 which are communicated through a first sealing door 24; the sample preparation amplification analysis area comprises an analysis buffer chamber 4 and a sample preparation amplification analysis chamber 3 which are communicated through a second sealing door 44; the openable outer window is not arranged in the two areas.
The ventilation and filtration system comprises an exhaust device and a fresh air device, and the fresh air device is respectively conveyed into each chamber through a pipeline in a pipeline interlayer; the exhaust device is connected with the exhaust outlets of the chambers through exhaust branch pipes, the exhaust outlets are arranged below the chambers, and the exhaust branch pipes are provided with electric closed regulating valves; the air outlet of the sample preparation amplification analysis chamber is connected with the high-efficiency filter 33, and the air outlet of the reagent preparation chamber is connected with the filter; the exhaust device is provided with chain start and stop, the exhaust fan is started before the air feeder is started, and the sequence is opposite when the air feeder is shut down. The high efficiency filter 33 is provided in the laboratory in this embodiment due to space problems in the sample preparation amplification analysis chamber.
The analysis buffer chamber 4 comprises a hand washing sink II 41, a wardrobe II42 and a shoe cover cabinet II43, and the pressure in the chamber is-10 Pa; the sample preparation, amplification and analysis chamber comprises a full-automatic nucleic acid purification and fluorescence PCR analysis system 31 and a pressure steam sterilization pot 32, and the pressure in the chamber is-20 Pa. The preparation buffer chamber comprises a hand washing sink I21, a wardrobe I22 and a shoe cover cabinet I23, and the pressure in the chamber is +10 Pa; the reagent preparation chamber comprises a workbench and a test bed, and the pressure in the chamber is +20 Pa.
And ultraviolet germicidal lamps are arranged in the sample preparation, amplification and analysis area, the reagent preparation area and the transfer window and are controlled by the control system room.
The fresh air device comprises a fresh air unit 45, a fresh air taking pipe 46, a fresh air main air pipe 47, a fresh air branch air pipe 48, a fresh air electric air quantity regulating valve 49 and a fresh air port 50. The fresh air unit adopts a direct expansion type air conditioning unit, and the functional section of the direct expansion type air conditioning unit comprises: an electric preheating section 51, a primary effect filtering section 52, a medium effect filtering I section 53, a direct expansion section 54, an electric heating section 55, a blower section 56, a flow equalizing section 57, a medium effect filtering II section 53', a humidifying section 58 and a blowing section 59; fresh air unit gets tuber pipe and external intercommunication through the new trend, the new trend is got and is connect the new trend and get the wind gap on the tuber pipe, the new trend is got the rain-proof tripe wind gap of wind gap for taking the filter screen, rain-proof tripe wind gap base limit is not less than 2.5 meters from ground. The fresh air unit is connected with the fresh air branch pipe through a fresh air main pipe; the fresh air branch pipe is connected with a reagent preparation chamber, a preparation buffer chamber, a sample preparation amplification analysis chamber and an analysis buffer chamber; the fresh air branch pipe is provided with an electric air volume adjusting valve; the electric air volume adjusting valve is connected with an indoor fresh air inlet through a flexible connection 60; the fresh air port includes but is not limited to the following forms: high-efficiency air supply outlet, micropore air supply outlet 61 and double-layer shutter air opening.
The exhaust device comprises an exhaust outlet 62, an electric air volume adjusting valve, a flexible connection, an exhaust branch pipe 63, an exhaust main pipe 64, an exhaust static pressure box I65, a check valve 66, an exhaust fan 67, an exhaust static pressure box II 68 and an exhaust outlet 69; the air outlet is a single-layer shutter air port with a filter screen between the preparation room and the preparation buffer room; the air outlets are arranged in the analysis room and the analysis buffer room and provided with efficient filters and can be used for in-situ disinfection and leakage detection, and the air outlets are connected with the electric air quantity regulating valve through flexible connection; the electric air volume adjusting valve is connected with the main air exhaust pipe through the branch air exhaust pipe; the main exhaust pipe is connected with the first exhaust static pressure box; the first exhaust static pressure box is connected with a check valve, and the check valve is connected with an exhaust fan; the exhaust fan is used and prepared; the exhaust fan is connected with the second exhaust static pressure box; the air exhaust static pressure box is connected with an air exhaust outlet; the air exhaust outlet is communicated with outdoor air by adopting a single-layer rainproof louver air port with a filter screen.
The electric regulating valves in the fresh air device and the exhaust device control the indoor pressure difference by changing the air volume, and the fresh air device and the exhaust device keep a closed state in a non-use stage and an indoor disinfection state, so that the indoor air tightness is ensured, and the disinfection effect is further ensured. The air supply and exhaust valve maintains the dynamic balance of the room pressure gradient according to the set air quantity.
It is apparent that those skilled in the art can make various changes and modifications to the embodiments of the present invention without departing from the spirit and scope of the embodiments of the present invention. Thus, if such modifications and variations of the embodiments of the present invention fall within the scope of the claims and their equivalents, the present invention is also intended to include such modifications and variations.
Claims (6)
1. A PCR biological safety detection cabin is characterized in that: the main structure of the container is a container, the interior of the container is divided into four independent areas, namely a reagent preparation area, a sample preparation amplification analysis area, a ventilation and filtration system area and a control system area;
the reagent preparation area is communicated with the sample preparation amplification analysis area through a transfer window; the reagent preparation area and the sample preparation amplification analysis area are used as independent inner core spaces, and a pipeline interlayer is arranged between the top of the reagent preparation area and the outer box body;
the ventilation and filtration system of the ventilation and filtration system area is respectively connected with the reagent preparation area and the sample preparation amplification analysis area through pipelines arranged in the interlayer; the power distribution and control system of the control system area is connected with the reagent preparation area and the sample preparation amplification analysis area through a pipeline interlayer;
the reagent preparation area comprises a preparation buffer chamber and a reagent preparation chamber which are communicated through a first sealing door;
the sample preparation amplification analysis area comprises an analysis buffer chamber and a sample preparation amplification analysis chamber which are communicated through a second sealing door;
and ultraviolet germicidal lamps are arranged in the sample preparation amplification analysis chamber area and the reagent preparation chamber area and are controlled by the control system chamber.
2. The PCR biosafety detection chamber according to claim 1, wherein the ventilation and filtration system comprises an exhaust device and a fresh air device, and the fresh air device is respectively conveyed to each chamber through a pipeline in the pipeline interlayer; the exhaust device is connected with the exhaust outlets of all the chambers through exhaust branch pipes, the exhaust outlets are arranged below all the chambers, and the exhaust outlets of the sample preparation amplification analysis chamber are connected with the high-efficiency filter.
3. The PCR biological safety detection chamber according to claim 1, wherein the analysis buffer chamber comprises a hand washing sink, a wardrobe and a shoe cover cabinet, and the pressure in the chamber is-10 Pa; the sample preparation amplification analysis chamber comprises a full-automatic nucleic acid purification and fluorescence PCR analysis system and a pressure steam sterilization pot, and the pressure in the chamber is-20 Pa.
4. The PCR biological safety detection chamber according to claim 1, wherein the preparation buffer chamber comprises a hand washing sink, a wardrobe and a shoe cover cabinet, and the pressure in the chamber is +10 Pa; the reagent preparation chamber comprises a workbench and a test bed, and the pressure in the chamber is +20 Pa.
5. The PCR biosafety detection cabin of claim 2, wherein the fresh air device adopts a direct expansion type air conditioning unit, and the functional section of the fresh air device sequentially comprises an electric preheating section, a primary effect filtering section, a medium effect filtering I section, a direct expansion section, an electric heating section, a blower section, a flow equalizing section, a medium effect filtering II section, a humidifying section and a blowing section; the fresh air inlet of each chamber adopts a shutter air port for preventing insects and rain.
6. The PCR biosafety test chamber of claim 2, wherein: the exhaust device comprises one exhaust fan and two exhaust fans, and the exhaust fans are provided with check valves.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022508445.4U CN215291660U (en) | 2020-11-03 | 2020-11-03 | PCR biological safety detection cabin |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN202022508445.4U CN215291660U (en) | 2020-11-03 | 2020-11-03 | PCR biological safety detection cabin |
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| Publication Number | Publication Date |
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| CN215291660U true CN215291660U (en) | 2021-12-24 |
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| Application Number | Title | Priority Date | Filing Date |
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| CN202022508445.4U Active CN215291660U (en) | 2020-11-03 | 2020-11-03 | PCR biological safety detection cabin |
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Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114961355A (en) * | 2022-06-17 | 2022-08-30 | 延安花香医疗应急装备制造有限公司 | Portable PCR shelter laboratory |
| CN115095187A (en) * | 2022-03-24 | 2022-09-23 | 成都格力新晖医疗装备有限公司 | Mobile laboratory and cabin body mechanism thereof |
-
2020
- 2020-11-03 CN CN202022508445.4U patent/CN215291660U/en active Active
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN115095187A (en) * | 2022-03-24 | 2022-09-23 | 成都格力新晖医疗装备有限公司 | Mobile laboratory and cabin body mechanism thereof |
| CN115095187B (en) * | 2022-03-24 | 2023-10-03 | 成都格力新晖医疗装备有限公司 | Mobile laboratory and cabin mechanism thereof |
| CN114961355A (en) * | 2022-06-17 | 2022-08-30 | 延安花香医疗应急装备制造有限公司 | Portable PCR shelter laboratory |
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