CN108969738A - A kind of moxa-moxibustion health-care patch - Google Patents

A kind of moxa-moxibustion health-care patch Download PDF

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CN108969738A
CN108969738A CN201810860643.1A CN201810860643A CN108969738A CN 108969738 A CN108969738 A CN 108969738A CN 201810860643 A CN201810860643 A CN 201810860643A CN 108969738 A CN108969738 A CN 108969738A
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layer
moxa
mass
sticker
iron powder
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李绍文
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/17Gnetophyta, e.g. Ephedraceae (Mormon-tea family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/286Carthamus (distaff thistle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/47Euphorbiaceae (Spurge family), e.g. Ricinus (castorbean)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/484Glycyrrhiza (licorice)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/533Leonurus (motherwort)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9068Zingiber, e.g. garden ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/46Ingredients of undetermined constitution or reaction products thereof, e.g. skin, bone, milk, cotton fibre, eggshell, oxgall or plant extracts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/70Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
    • A61K9/7023Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/333Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH

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Abstract

The invention discloses a kind of moxa-moxibustion health-care patch, which includes the nonwoven layer set gradually from outside to inside, sticker layer, heating layer, medicine layer, separation layer and the adherent layer with the cooperation of sticker layer;Separation layer includes that mass ratio is 100:60 ~ 70:30 ~ 35:10 ~ 12:5 ~ 7:12 ~ 15 polyamide, epoxy resin, polyglycol ether, polyallylamine hydrochloride, graphene oxide and nanometer calcium carbonate;Adherent layer is EVOH and PP composite membrane and the side PP is arranged close to the sticker layer, has the advantages that medicine layer and external environment isolation reducing loss.

Description

A kind of moxa-moxibustion health-care patch
Technical field
The present invention relates to a kind of moxa-moxibustion health-care patchs.
Background technique
Moxa-moxibustion is Ai heat stimulation body surface point or privileged site that the moxa-moxibustion material made of folium artemisiae argyi generates, passes through excitation Activity through gas adjusts the biochemical functions of human disorder, to reach a kind for the treatment of method for purpose of preventing and curing diseases.
There are also moxa-moxibustion patches in the market, but the liquid of folium artemisiae argyi or folium artemisiae argyi tanning is volatile, is long placed in vulnerable.
Summary of the invention
The object of the present invention is to provide a kind of moxa-moxibustion health-care patch, has and medicine layer and external environment isolation are reduced into the excellent of loss Point.
Above-mentioned technical purpose of the invention has the technical scheme that
A kind of moxa-moxibustion health-care patch, including set gradually from outside to inside nonwoven layer, sticker layer, heating layer, medicine layer, every Absciss layer and the adherent layer cooperated with sticker layer;The separation layer includes polyamide, epoxy resin, polyglycol ether, polyallyl Amine hydrochlorate, graphene oxide and nanometer calcium carbonate, by mass, in the separation layer, polyamide, epoxy resin, poly- second Glycol ethers, polyallylamine hydrochloride, graphene oxide and nanometer calcium carbonate formula ratio ratio be 100: 60~70: 30~35: 10~12: 5~7: 12~15;The adherent layer is EVOH and PP composite membrane and the side PP is arranged close to the sticker layer.
By adopting the above technical scheme, medicine layer is isolated with external environment by separation layer, it loses during reducing storage, Increase simultaneously with the water-flowing amount that temperature increases the separation layer, i.e., in treatment, medical fluid can play the work for the treatment of by the separation layer With.
Further preferably are as follows: by mass, in the separation layer, polyamide, epoxy resin, polyglycol ether, polyene The formula ratio ratio of propylamine hydrochloride, graphene oxide and nanometer calcium carbonate is 100: 66: 32: 11: 6: 13.
Further preferably are as follows: the sticker layer includes natural rubber, copal, antioxidant D NP, glycerine, fructus rosae Oil, lauryl sodium sulfate, lecithin, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder and pearl powder;By mass, in institute It states in sticker layer, the natural rubber, copal, antioxidant D NP, glycerine, rose hip oil, lauryl sodium sulfate, ovum Phosphatide, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder and pearl powder formula ratio ratio be 100: 42~45: 2~4: 17~20: 6~8: 5~6: 5~6: 14~16: 2~4: 1.0~1.5: 0.8~1.0: 2~4.
By adopting the above technical scheme, sticker layer is using natural rubber as rubber elastomer, using copal as tackifier, to prevent Old agent DNP is anti-aging agent, using a certain proportion of glycerine and rose hip oil as softening agent, so that resin dispersion is mutually in bonding interface One very thin viscous layer is formed, which can occur VISCOUS FLOW under external force, moisten by viscous layer, to make just Viscous force increases, and plays the role of a kind of moxa-moxibustion health-care patch and skin that are bonded the application.In addition, adding carbonic acid in sticker layer Calcium, volcanic ash, sodium bicarbonate, iron powder and pearl powder, and utilize glycerine, rose hip oil, lauryl sodium sulfate and lecithin The peptizaiton of rouge, can using the joint of volcanic ash, sodium bicarbonate, iron powder and pearl powder while can play filling effect Play the role of reducing pure water and glue and the effect for keeping salt water and glue, its viscosity in different media can be improved: research hair Existing, the sticker layer of the application is easy to reunite in salt water and easily disperses in water, and skin surface is easy to perspire and especially paste When moxa-moxibustion health-care patch in the raised situation of skin surface temperature, so skin surface typically contains certain salinity, such case On the skin, and residual quantity is significantly lower than the prior art after tearing sticker layer off for the adherency of lower sticker layer, and even if having remained with water It can wash away easily.
Further preferably are as follows: by mass, in the sticker layer, the natural rubber, copal, antioxidant D NP, Glycerine, rose hip oil, lauryl sodium sulfate, lecithin, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder and pearl powder Formula ratio ratio is 100: 44: 3: 18: 7: 5.5: 5.5: 15: 3: 1.2: 0.9: 3.
Further preferably are as follows: the sticker layer further includes seawood meal, sodium chloride and carboxymethyl chitosan;By mass, exist In the sticker layer, the natural rubber, copal, antioxidant D NP, glycerine, rose hip oil, lauryl sodium sulfate, Lecithin, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder, pearl powder, seawood meal, sodium chloride and carboxymethyl chitosan formula Amount is than being 100: 44: 3: 18: 7: 5.5: 5.5: 15: 3: 1.2: 0.9: 3: 2: 6: 4.
As the temperature rises, gum softening is more thorough, and the glue to reharden after softening and applied skin force are stronger, glue residua Amount is bigger and is more difficult to remove.By adopting the above technical scheme, it is further reduced the effect of pure water and glue and keeps the work of salt water and glue With.
Further preferably are as follows: the heating layer includes iron powder, active powdered carbon, sodium chloride, calcium chloride and water-absorbing resin;By matter Meter, in heating layer, iron powder, active powdered carbon, sodium chloride, calcium chloride and water-absorbing resin formula ratio ratio be 100: 8~12: 5 ~8: 4~6: 10~12.
By adopting the above technical scheme, the purpose of fever is played using the property of iron powder oxidation heat liberation in air.
Further preferably are as follows: by mass, in heating layer, iron powder, active powdered carbon, sodium chloride, calcium chloride and water suction tree The formula ratio ratio of rouge is 100: 10: 6: 5: 11.
Further preferably are as follows: the heating layer further includes green vitriol, sodium bicarbonate and glucose;By mass, in the hair In thermosphere, iron powder, active powdered carbon, sodium chloride, calcium chloride, water-absorbing resin, green vitriol, sodium bicarbonate and glucose formula ratio ratio be 100:10:6:5:11:3:2:5.
By adopting the above technical scheme, the maximum temperature after heating layer effect is low, and 40 DEG C or more retention times are longer, reduce High-temperature a possibility that burning, extends action time to skin.
Further preferably are as follows: the medicine layer is prepared by the following method to obtain: Chinese mugwort, safflower, lopseed, benefit is female Grass, ginger, Chinese ephedra, lavender and Radix Glycyrrhizae mix after crushing respectively, and rice vinegar and water is added, and decoct 4hr, filter to take decocting liquid, are concentrated Obtain concentrate;Pig scrap is taken, baked wheaten cake of useing force is forged, and to be popular in as degree, pours into concentrate while hot, stirring to medical fluid exhausts, cooling To room temperature;By mass, Chinese mugwort, safflower, lopseed, motherwort, ginger, Chinese ephedra, lavender, Radix Glycyrrhizae, rice vinegar, water and pig scrap Amount ratio be 1: 0.3~0.5: 0.6~0.8: 0.3~0.5: 0.1~0.2: 0.6~0.8: 0.2~0.4: 0.4~0.6: 10 ~15: 2~3: 20~25.
Chinese mugwort, bitter and it is pungent, it is nontoxic, wash smoked take and all may be used;There is rationale blood, expels cold-dampness, is menstruation regulating miscarriage prevention, warming channel for arresting bleeding, clear Hot antitussive and expectorant and other effects;Cure mainly irregular menstruation, diseases such as blood, threatened abortion, fertility under crymodynia, vaginal bleeding during pregnancy in abdomen.
Safflower, it is acrid in flavour and warm in nature;Converge to heart and liver channels;Blood circulation, removing blood stasis and acesodyne;For menostasis, dysmenorrhea, lochia, abdominal mass ruffian Block, injury from falling down, sore swell and ache curative.
Lopseed, sweet, acrid, warm;Enter lung, liver two passes through;Dispelling wind and eliminating dampness, relaxing tendons and activating collaterals, promoting blood circulation and stopping pain, solution poison rash.
Motherwort, it is bitter, pungent, it is slightly cold;Return liver, pericardium, bladder meridian;Promoting blood circulation for regulating menstruation, inducing diuresis to remove edema are clearing heat and detoxicating;For the moon Through uncomfortable, dysmenorrhea menostasis, lochiorrhagia, edema and little urine, sore swollen toxin.
Ginger, ginger have diverging, preventing or arresting vomiting, cough-relieving and other effects in traditional Chinese medicine and pharmacy.
Chinese ephedra, pungent, slight bitter, temperature;Return lung, bladder meridian;Inducing sweat and dispelling exogenous evils are freeinged lung and relieving asthma, inducing diuresis for removing edema.
By adopting the above technical scheme, Chinese mugwort, safflower, lopseed, motherwort, ginger, Chinese ephedra are mixed in specific proportions, is led to The activity of stimulating Qi of meridian is crossed to adjust the biochemical functions of human disorder, utilizes the therapeutic effect of lavender and the reconciliation of Radix Glycyrrhizae Effect further increases comfort, supplements energy;Medicinal powder is substituted with the mode of pig scrap absorption medical fluid directly to act on, and compares medicine Powder, the effective component in medical fluid is released and it easily penetrates into skin and is absorbed, and greatly improves its effect.
In conclusion the invention has the following advantages: medicine layer is isolated with external environment by separation layer, reduction is deposited It loses during putting, while increasing with the water-flowing amount that temperature increases the separation layer, i.e., in treatment, medical fluid can pass through the isolation Layer, plays the role for the treatment of;Viscosity is good, and glue residua is few and easy removal, reduces skin sense of discomfort;Excessive temperature is reduced to skin A possibility that burning, long action time;The biochemical functions of human disorder are adjusted by the activity of stimulating Qi of meridian, increase is supported Drag, promoting blood circulation and removing obstruction in channels, antiallergy are mild non-stimulated.
Specific embodiment
This specific embodiment is only explanation of the invention, is not limitation of the present invention, those skilled in the art Member can according to need the modification that not creative contribution is made to the present embodiment after reading this specification, but as long as at this All by the protection of Patent Law in the protection scope of invention.
Embodiment 1A: a kind of separation layer is prepared by the following method to obtain:
Polyglycol ether and polyallylamine hydrochloride are added in chloroform, is dispersed with stirring uniformly, is warming up to 55 DEG C, to anti- It answers and polyamide and epoxy resin is added in system and is dispersed with stirring uniformly;40 DEG C are cooled to, graphene oxide and nanometer are added Calcium carbonate is dispersed with stirring uniformly forced air drying at 40 DEG C;
By mass, the amount ratio of chloroform and polyamide is 6: 1;
By mass, in the isolation layer, polyamide, epoxy resin, polyglycol ether, polyallylamine hydrochloride, oxidation Graphene and the formula ratio of nanometer calcium carbonate ratio are 100: 66: 32: 11: 6: 13.
Embodiment 1B: a kind of separation layer, with embodiment 1A the difference is that,
By mass, in the isolation layer, polyamide, epoxy resin, polyglycol ether, polyallylamine hydrochloride, oxidation Graphene and the formula ratio of nanometer calcium carbonate ratio are 100: 60: 30: 10: 5: 12.
Embodiment 1C: a kind of separation layer, with embodiment 1A the difference is that,
By mass, in the isolation layer, polyamide, epoxy resin, polyglycol ether, polyallylamine hydrochloride, oxidation Graphene and the formula ratio of nanometer calcium carbonate ratio are 100: 70: 35: 12: 7: 15.
Embodiment 2A: a kind of sticker layer is prepared by the following method to obtain:
Glycerine, rose hip oil, lauryl sodium sulfate and lecithin are added in n-hexane, is dispersed with stirring uniformly, rises Natural rubber and copal are added into reaction system and is dispersed with stirring uniformly to 60 DEG C for temperature;45 DEG C are cooled to, is added anti- Old agent DNP, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder, pearl powder, seawood meal, sodium chloride and carboxymethyl chitosan, stirring It is uniformly dispersed, forced air drying at 40 DEG C;
By mass, the amount ratio of n-hexane and natural rubber is 10: 1;
By mass, in sticker layer, natural rubber, copal, antioxidant D NP, glycerine, rose hip oil, 12 Sodium alkyl sulfate, lecithin, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder, pearl powder, seawood meal, sodium chloride and carboxymethyl The formula ratio ratio of chitosan is 100: 44: 3: 18: 7: 5.5: 5.5: 15: 3: 1.2: 0.9: 3: 2: 6: 4.
Embodiment 2B: a kind of sticker layer is prepared by the following method to obtain:
Glycerine, rose hip oil, lauryl sodium sulfate and lecithin are added in n-hexane, is dispersed with stirring uniformly, rises Natural rubber and copal are added into reaction system and is dispersed with stirring uniformly to 60 DEG C for temperature;45 DEG C are cooled to, is added anti- Old agent DNP, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder and pearl powder are dispersed with stirring uniformly forced air drying at 40 DEG C;
By mass, the amount ratio of n-hexane and natural rubber is 10: 1;
By mass, in sticker layer, natural rubber, copal, antioxidant D NP, glycerine, rose hip oil, 12 Sodium alkyl sulfate, lecithin, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder and pearl powder formula ratio ratio be 100: 44: 3: 18∶7∶5.5∶5.5∶15∶3∶1.2∶0.9∶3。
Embodiment 2C: a kind of sticker layer, with embodiment 2B the difference is that,
By mass, in sticker layer, natural rubber, copal, antioxidant D NP, glycerine, rose hip oil, 12 Sodium alkyl sulfate, lecithin, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder and pearl powder formula ratio ratio be 100: 42: 2: 17∶6∶5∶5∶14∶2∶1.0∶0.8∶2。
Embodiment 2D: a kind of sticker layer, with embodiment 2B the difference is that,
By mass, in sticker layer, natural rubber, copal, antioxidant D NP, glycerine, rose hip oil, 12 Sodium alkyl sulfate, lecithin, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder and pearl powder formula ratio ratio be 100: 45: 4: 20∶8∶6∶6∶16∶4∶1.5∶1.0∶4。
Embodiment 3A: a kind of heating layer, by iron powder, active powdered carbon, sodium chloride, calcium chloride, water-absorbing resin, green vitriol, carbon Sour hydrogen sodium and glucose are mixed to get;By mass, iron powder, active powdered carbon, sodium chloride, calcium chloride, water-absorbing resin, green vitriol, carbon The formula ratio ratio of sour hydrogen sodium and glucose is 100: 10: 6: 5: 11: 3: 2: 5.
Embodiment 3B: a kind of heating layer, by iron powder, active powdered carbon, sodium chloride, calcium chloride, water-absorbing resin, green vitriol, carbon Sour hydrogen sodium and glucose are mixed to get;By mass, the formula ratio of iron powder, active powdered carbon, sodium chloride, calcium chloride and water-absorbing resin Than being 100: 10: 6: 5: 11.
Embodiment 3C: a kind of heating layer, with embodiment 3B the difference is that, by mass, iron powder, active powdered carbon, The formula ratio ratio of sodium chloride, calcium chloride and water-absorbing resin is 100: 8: 5: 4: 10.
Embodiment 3D: a kind of heating layer, with embodiment 3B the difference is that, by mass, iron powder, active powdered carbon, The formula ratio ratio of sodium chloride, calcium chloride and water-absorbing resin is 100: 12: 8: 6: 12.
Embodiment 4A: a kind of medicine layer is prepared by the following method to obtain:
It is mixed after Chinese mugwort, safflower, lopseed, motherwort, ginger, Chinese ephedra, lavender and Radix Glycyrrhizae are crushed respectively, rice is added Vinegar and water decoct 4hr, filter to take decocting liquid, be concentrated to get concentrate;Pig scrap is taken, baked wheaten cake of useing force is forged, to be popular in for degree, while hot Concentrate is poured into, stirring to medical fluid is exhausted, is cooled to room temperature;
By mass, Chinese mugwort, safflower, lopseed, motherwort, ginger, Chinese ephedra, lavender, Radix Glycyrrhizae, rice vinegar, water and the pig iron The amount ratio of bits is 1: 0.4: 0.7: 0.4: 0.15: 0.7: 0.3: 0.5: 12: 2.5: 22.
Embodiment 4B: a kind of medicine layer, with embodiment 4A the difference is that, it is by mass, Chinese mugwort, safflower, deep Grass, motherwort, ginger, Chinese ephedra, lavender, Radix Glycyrrhizae, rice vinegar, water and pig scrap amount ratio be 1: 0.3: 0.6: 0.3: 0.1: 0.6∶0.2∶0.4∶10∶2∶20。
Embodiment 4C: a kind of medicine layer, with embodiment 4A the difference is that, it is by mass, Chinese mugwort, safflower, deep Grass, motherwort, ginger, Chinese ephedra, lavender, Radix Glycyrrhizae, rice vinegar, water and pig scrap amount ratio be 1: 0.5: 0.8: 0.5: 0.2: 0.8∶0.4∶0.6∶15∶3∶25。
Embodiment 5: a kind of moxa-moxibustion health-care patch, including set gradually from outside to inside nonwoven layer, sticker layer, heating layer, Medicine layer, separation layer and the adherent layer with the cooperation of sticker layer.
Separation layer derives from embodiment 1A, and sticker layer derives from embodiment 2A, and heating layer derives from embodiment 3A, medicine layer From embodiment 4A.Adherent layer is EVOH and PP composite membrane and the side PP is arranged close to sticker layer.
Embodiment 6: a kind of moxa-moxibustion health-care patch, the difference is that, sticker layer derives from embodiment 2B with embodiment 4, Heating layer derives from embodiment 3B.
Embodiment 7: a kind of moxa-moxibustion health-care patch, the difference is that, separation layer derives from embodiment 1B with embodiment 4, Sticker layer derives from embodiment 2C, and heating layer derives from embodiment 3C, and medicine layer derives from embodiment 4B.
Embodiment 8: a kind of moxa-moxibustion health-care patch, the difference is that, separation layer derives from embodiment 1C with embodiment 4, Sticker layer derives from embodiment 2D, and heating layer derives from embodiment 3D, and medicine layer derives from embodiment 4C.
1, the performance characterization of separation layer
(1) test sample: embodiment 1A-1C, thickness control is in 0.5mm.
(2) test content
Test object is tested in the water-flowing amount of different temperatures (under an atmospheric pressure).It parallel test 5 times, is averaged.
Water-flowing amount under different temperatures is as shown in table 1.Table 1 is shown: being increased with temperature, the water-flowing amount of embodiment 1A-1C increases Add;Water-flowing amount at the same temperature compares, embodiment 1A < embodiment 1B < embodiment 1C, wherein embodiment 1A at 0-30 DEG C Water-flowing amount be 0, be more suitable for saving.
The performance characterization (unit: μ l/hr) of 1 separation layer of table
2, the performance characterization of sticker layer
(1) test sample: embodiment 2A-2D and control sample 1-2.
Control sample 1: a kind of medical pressure sensitive adhesive (i.e. sticker layer), purchased from the limited public affairs of the white scape environmental protection science and technology in the Foshan City South Sea Department, the pressure sensitive adhesive of selection are epoxide-resin glue.
Control sample 2: a kind of sticker layer is prepared by the following method to obtain: naphthenic oil, stirring point being added in n-hexane It dissipates uniformly, is warming up to 60 DEG C, natural rubber and copal are added into reaction system and are dispersed with stirring uniformly;It is cooled to 45 DEG C, antioxidant D NP is added, uniformly forced air drying at 40 DEG C is dispersed with stirring;By mass, the use of n-hexane and natural rubber Amount is than being 10: 1;By mass, in sticker layer, natural rubber, copal, antioxidant D NP and naphthenic oil formula ratio ratio It is 100: 44: 3: 25.
(2) test content
1. taking 50mg test sample, it is individually positioned in the different solvents of 100ml different temperatures, with 50r/min's Speed is stirred 2min, observes its dispersion.5 groups of parallel test.
Such as test result of the dispersion in different solvents under different temperatures is as shown in table 2.Table 2 is shown: in pure water, The dispersibility of embodiment 2A-2D is better than control sample 1-2, and deposits as temperature increases dispersibility of the embodiment 2A-2D in pure water In downward trend, dispersibility of the embodiment 2A in pure water is best, and embodiment 2B takes second place;When adding sodium chloride in pure water Afterwards, the dispersibility decline of embodiment 2A-2D is obvious.
The dispersion in different solvents under 2 different temperatures of table
2. taking non-woven fabrics, coat test sample on it, the test sample of coating with a thickness of 2mm, for use.Random choosing is real Object is tested, with water cleaner arm and is wiped, the non-woven fabrics for having smeared test sample, firm pasting are pasted;In the outer of non-woven fabrics The water bag (every the water bag that 15min more renews, it is ensured that temperature control) of a temperature control is placed in side, places and tears non-woven fabrics off simultaneously after a certain period of time Whether observation skin surface has glue residua, and then spraying 5ml water on the skin and observing skin surface again with paper handkerchief wiping 10s is It is no to have glue residua.5 groups of parallel test.
The test result of usage experience is as shown in table 3.Table 3 is shown: with pasting the raising of temperature and paste the extension of time, There are increased trend for the glue residua of test sample;It is compared with control sample 1-2, the glue residua amount of embodiment 2A-2D is decreased obviously And (glue residua intensity is low) can be cleaned with water, wherein embodiment 2A is best, and embodiment 2B takes second place.
3 usage experience of table
3, the performance characterization of heating layer
(1) test sample: embodiment 3A-3D and control sample 3.
Control sample 3: a kind of heating layer is mixed to get by iron powder, active powdered carbon, sodium chloride, vermiculite and water-absorbing resin;It presses Quality meter, iron powder, active powdered carbon, sodium chloride, vermiculite and water-absorbing resin formula ratio ratio be 100: 10: 6: 5: 11.
(2) test content
50ml beaker is taken, 10g test sample and thermometer are put into, its is exposed in air, monitor its temperature change feelings Condition records the time of 40 DEG C of its maximum temperature and holding or more.5 groups of parallel test.
The test result of heating layer is as shown in table 4.Table 4 is shown: comparing control sample 3, the maximum temperature of embodiment 3A-3D is more Low, 40 DEG C or more retention times are longer, reduce excessive temperature and a possibility that burning, extend action time to skin.
The performance characterization of 4 heating layer of table
The performance characterization of moxa-moxibustion health-care patch
Example 5 is covered on the belly for the patient that one has dysmenorrhoea, a sense of warmth, is comfortable on after use, warp Pain is relieved.
Example 5 is covered on the belly for the patient that one has cold body, a sense of warmth, is comfortable on after use, body It is cold to be relieved.
The specific implementation of the invention is not to be limited to these illustrations for the above content, and technology belonging to the present invention is led For the those of ordinary skill in domain, without departing from the inventive concept of the premise, a number of simple deductions or replacements can also be made, It all shall be regarded as belonging to present invention scope of patent protection determined by the appended claims.

Claims (9)

1. a kind of moxa-moxibustion health-care patch, which is characterized in that including set gradually from outside to inside nonwoven layer, sticker layer, heating layer, Medicine layer, separation layer and the adherent layer with the cooperation of sticker layer;The separation layer include polyamide, epoxy resin, polyglycol ether, Polyallylamine hydrochloride, graphene oxide and nanometer calcium carbonate, by mass, in the separation layer, polyamide, asphalt mixtures modified by epoxy resin Rouge, polyglycol ether, polyallylamine hydrochloride, graphene oxide and nanometer calcium carbonate formula ratio ratio be 100:60 ~ 70:30 ~35:10~12:5~7:12~15;The adherent layer is EVOH and PP composite membrane and the side PP is arranged close to the sticker layer.
2. a kind of moxa-moxibustion health-care patch according to claim 1, which is characterized in that by mass, in the separation layer, gather Amide, epoxy resin, polyglycol ether, polyallylamine hydrochloride, graphene oxide and nanometer calcium carbonate formula ratio ratio be 100:66:32:11:6:13。
3. a kind of moxa-moxibustion health-care patch according to claim 1 or 2, which is characterized in that the sticker layer include natural rubber, Copal, antioxidant D NP, glycerine, rose hip oil, lauryl sodium sulfate, lecithin, calcium carbonate, volcanic ash, bicarbonate Sodium, iron powder and pearl powder;By mass, in the sticker layer, the natural rubber, copal, antioxidant D NP, third Triol, rose hip oil, lauryl sodium sulfate, lecithin, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder and pearl powder are matched Side's amount is than being 100:42 ~ 45:2 ~ 4:17 ~ 20:6 ~ 8:5 ~ 6:5 ~ 6:14 ~ 16:2 ~ 4:1.0 ~ 1.5:0.8 ~ 1.0:2 ~ 4.
4. a kind of moxa-moxibustion health-care patch according to claim 3, which is characterized in that by mass, in the sticker layer, institute State natural rubber, copal, antioxidant D NP, glycerine, rose hip oil, lauryl sodium sulfate, lecithin, calcium carbonate, fire Mountain ash, sodium bicarbonate, iron powder and pearl powder formula ratio ratio be 100:44:3:18:7:5.5:5.5:15:3:1.2:0.9:3.
5. a kind of moxa-moxibustion health-care patch according to claim 3, which is characterized in that the sticker layer further includes seawood meal, chlorine Change sodium and carboxymethyl chitosan;By mass, in the sticker layer, the natural rubber, copal, antioxidant D NP, third Triol, rose hip oil, lauryl sodium sulfate, lecithin, calcium carbonate, volcanic ash, sodium bicarbonate, iron powder, pearl powder, seaweed The formula ratio ratio of powder, sodium chloride and carboxymethyl chitosan is 100:44:3:18:7:5.5:5.5:15:3:1.2:0.9:3:2:6: 4。
6. a kind of moxa-moxibustion health-care patch according to claim 1 or 2, which is characterized in that the heating layer includes iron powder, activity Powdered carbon, sodium chloride, calcium chloride and water-absorbing resin;By mass, in heating layer, iron powder, active powdered carbon, sodium chloride, calcium chloride Formula ratio ratio with water-absorbing resin is 100:8 ~ 12:5 ~ 8:4 ~ 6:10 ~ 12.
7. a kind of moxa-moxibustion health-care patch according to claim 6, which is characterized in that by mass, in heating layer, iron powder, Active powdered carbon, sodium chloride, calcium chloride and water-absorbing resin formula ratio ratio be 100:10:6:5:11.
8. a kind of moxa-moxibustion health-care patch according to claim 6, which is characterized in that the heating layer further includes green vitriol, carbonic acid Hydrogen sodium and glucose;By mass, iron powder, active powdered carbon, sodium chloride, calcium chloride, water-absorbing resin, green in the heating layer The formula ratio ratio of alum, sodium bicarbonate and glucose is 100:10:6:5:11:3:2:5.
9. a kind of moxa-moxibustion health-care patch according to claim 1 or 2, which is characterized in that the medicine layer is by the following method It is prepared: being mixed after Chinese mugwort, safflower, lopseed, motherwort, ginger, Chinese ephedra, lavender and Radix Glycyrrhizae are crushed respectively, is added Rice vinegar and water decoct 4hr, filter to take decocting liquid, be concentrated to get concentrate;Pig scrap is taken, baked wheaten cake of useing force is forged, and to be popular in as degree, is taken advantage of Heat pours into concentrate, and stirring to medical fluid is exhausted, is cooled to room temperature;By mass, Chinese mugwort, safflower, lopseed, motherwort, ginger, Chinese ephedra, lavender, Radix Glycyrrhizae, rice vinegar, water and pig scrap amount ratio be 1:0.3 ~ 0.5:0.6 ~ 0.8:0.3 ~ 0.5:0.1 ~ 0.2: 0.6~0.8:0.2~0.4:0.4~0.6:10~15:2~3:20~25。
CN201810860643.1A 2018-08-01 2018-08-01 A kind of moxa-moxibustion health-care patch Pending CN108969738A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN205515139U (en) * 2016-02-01 2016-08-31 蕲春艾都生物科技有限公司 Chinese mugwort essential oil physiotherapy subsides

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN205515139U (en) * 2016-02-01 2016-08-31 蕲春艾都生物科技有限公司 Chinese mugwort essential oil physiotherapy subsides

Non-Patent Citations (2)

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Title
孙世发: "《中华医方 内科篇 经络肢体病》", 31 March 2015, 科学技术文献出版社 *
黄滔: "石墨烯及环糊精在自组装多层膜中缓释作用研究", 《中国优秀硕士学位论文全文数据库 工程科技Ⅰ辑》 *

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Application publication date: 20181211