CN108957022B - 基于蛋白芯片的样品检测装置及方法 - Google Patents
基于蛋白芯片的样品检测装置及方法 Download PDFInfo
- Publication number
- CN108957022B CN108957022B CN201810929241.2A CN201810929241A CN108957022B CN 108957022 B CN108957022 B CN 108957022B CN 201810929241 A CN201810929241 A CN 201810929241A CN 108957022 B CN108957022 B CN 108957022B
- Authority
- CN
- China
- Prior art keywords
- unit
- sample
- plate washing
- washing
- guide rail
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Active
Links
- 238000001514 detection method Methods 0.000 title claims abstract description 51
- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 48
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 48
- 238000000034 method Methods 0.000 title abstract description 9
- 238000005406 washing Methods 0.000 claims abstract description 157
- 230000001360 synchronised effect Effects 0.000 claims abstract description 64
- 238000011534 incubation Methods 0.000 claims abstract description 45
- 239000000523 sample Substances 0.000 claims description 273
- 230000010355 oscillation Effects 0.000 claims description 17
- 239000003153 chemical reaction reagent Substances 0.000 claims description 11
- 238000012360 testing method Methods 0.000 claims description 9
- 238000009434 installation Methods 0.000 claims description 7
- 239000000969 carrier Substances 0.000 claims description 6
- 238000002156 mixing Methods 0.000 claims description 6
- 239000012472 biological sample Substances 0.000 claims description 4
- 239000011148 porous material Substances 0.000 claims description 2
- 238000010586 diagram Methods 0.000 description 8
- 238000005516 engineering process Methods 0.000 description 7
- 238000013461 design Methods 0.000 description 4
- 238000007493 shaping process Methods 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 230000003993 interaction Effects 0.000 description 3
- 238000005070 sampling Methods 0.000 description 3
- 208000023275 Autoimmune disease Diseases 0.000 description 2
- 238000004458 analytical method Methods 0.000 description 2
- 239000003086 colorant Substances 0.000 description 2
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 238000000018 DNA microarray Methods 0.000 description 1
- 238000002965 ELISA Methods 0.000 description 1
- 208000008589 Obesity Diseases 0.000 description 1
- 230000009471 action Effects 0.000 description 1
- 239000000427 antigen Substances 0.000 description 1
- 102000036639 antigens Human genes 0.000 description 1
- 108091007433 antigens Proteins 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 239000000090 biomarker Substances 0.000 description 1
- 210000001124 body fluid Anatomy 0.000 description 1
- 239000010839 body fluid Substances 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 230000007547 defect Effects 0.000 description 1
- 238000003745 diagnosis Methods 0.000 description 1
- 230000000694 effects Effects 0.000 description 1
- 238000004377 microelectronic Methods 0.000 description 1
- 238000005459 micromachining Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 235000020824 obesity Nutrition 0.000 description 1
- 210000002381 plasma Anatomy 0.000 description 1
- 230000008569 process Effects 0.000 description 1
- 238000011160 research Methods 0.000 description 1
- 238000012216 screening Methods 0.000 description 1
- 210000002966 serum Anatomy 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1004—Cleaning sample transfer devices
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1009—Characterised by arrangements for controlling the aspiration or dispense of liquids
- G01N35/1016—Control of the volume dispensed or introduced
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00138—Slides
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00029—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor provided with flat sample substrates, e.g. slides
- G01N2035/00099—Characterised by type of test elements
- G01N2035/00158—Elements containing microarrays, i.e. "biochip"
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N2035/00465—Separating and mixing arrangements
- G01N2035/00534—Mixing by a special element, e.g. stirrer
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00742—Type of codes
- G01N2035/00752—Type of codes bar codes
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/00584—Control arrangements for automatic analysers
- G01N35/00722—Communications; Identification
- G01N35/00732—Identification of carriers, materials or components in automatic analysers
- G01N2035/00821—Identification of carriers, materials or components in automatic analysers nature of coded information
- G01N2035/00831—Identification of carriers, materials or components in automatic analysers nature of coded information identification of the sample, e.g. patient identity, place of sampling
Landscapes
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Abstract
Description
Claims (5)
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810929241.2A CN108957022B (zh) | 2018-08-15 | 2018-08-15 | 基于蛋白芯片的样品检测装置及方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201810929241.2A CN108957022B (zh) | 2018-08-15 | 2018-08-15 | 基于蛋白芯片的样品检测装置及方法 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN108957022A CN108957022A (zh) | 2018-12-07 |
CN108957022B true CN108957022B (zh) | 2023-12-26 |
Family
ID=64470274
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201810929241.2A Active CN108957022B (zh) | 2018-08-15 | 2018-08-15 | 基于蛋白芯片的样品检测装置及方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN108957022B (zh) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN116099797A (zh) * | 2021-11-11 | 2023-05-12 | 山东博科生物产业有限公司 | 一种集洗板与试剂添加为一体的新型洗板机 |
Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06225752A (ja) * | 1993-02-05 | 1994-08-16 | Toyobo Co Ltd | Dnaプローブ自動測定装置およびサンプル中の核酸を測定する方法 |
CA2533219A1 (en) * | 2005-12-02 | 2007-06-02 | Hudson Control Group, Inc. | Systems and methods for automated proteomics research |
CN103257245A (zh) * | 2013-05-15 | 2013-08-21 | 北京源诚科仪生物技术有限公司 | 用于全自动化学发光免疫分析仪器的处理装置 |
CN104297505A (zh) * | 2014-11-04 | 2015-01-21 | 石家庄康普生科技有限公司 | 一种大容量高速准自动化学发光免疫分析仪 |
CN104597268A (zh) * | 2015-01-28 | 2015-05-06 | 烟台艾德康生物科技有限公司 | 一种集成化酶免分析仪 |
CN105277726A (zh) * | 2014-07-25 | 2016-01-27 | 广州瑞博奥生物科技有限公司 | 一种蛋白芯片全自动化高通量分析方法及装置 |
CN106802353A (zh) * | 2017-03-16 | 2017-06-06 | 烟台德瑞生物科技有限公司 | 全自动酶免发光分析仪 |
CN206731665U (zh) * | 2017-05-25 | 2017-12-12 | 烟台德迈生物科技有限公司 | 一种集成震荡孵育功能的洗板机构 |
CN208902747U (zh) * | 2018-08-15 | 2019-05-24 | 烟台艾德康生物科技有限公司 | 基于蛋白芯片的样品检测装置 |
-
2018
- 2018-08-15 CN CN201810929241.2A patent/CN108957022B/zh active Active
Patent Citations (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH06225752A (ja) * | 1993-02-05 | 1994-08-16 | Toyobo Co Ltd | Dnaプローブ自動測定装置およびサンプル中の核酸を測定する方法 |
CA2533219A1 (en) * | 2005-12-02 | 2007-06-02 | Hudson Control Group, Inc. | Systems and methods for automated proteomics research |
CN103257245A (zh) * | 2013-05-15 | 2013-08-21 | 北京源诚科仪生物技术有限公司 | 用于全自动化学发光免疫分析仪器的处理装置 |
CN105277726A (zh) * | 2014-07-25 | 2016-01-27 | 广州瑞博奥生物科技有限公司 | 一种蛋白芯片全自动化高通量分析方法及装置 |
CN104297505A (zh) * | 2014-11-04 | 2015-01-21 | 石家庄康普生科技有限公司 | 一种大容量高速准自动化学发光免疫分析仪 |
CN104597268A (zh) * | 2015-01-28 | 2015-05-06 | 烟台艾德康生物科技有限公司 | 一种集成化酶免分析仪 |
CN106802353A (zh) * | 2017-03-16 | 2017-06-06 | 烟台德瑞生物科技有限公司 | 全自动酶免发光分析仪 |
CN206731665U (zh) * | 2017-05-25 | 2017-12-12 | 烟台德迈生物科技有限公司 | 一种集成震荡孵育功能的洗板机构 |
CN208902747U (zh) * | 2018-08-15 | 2019-05-24 | 烟台艾德康生物科技有限公司 | 基于蛋白芯片的样品检测装置 |
Also Published As
Publication number | Publication date |
---|---|
CN108957022A (zh) | 2018-12-07 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN105277726B (zh) | 一种蛋白芯片全自动化高通量分析方法及装置 | |
CN103235147B (zh) | 分析装置的液体分配器 | |
CN205229171U (zh) | 一种样本试管类型自动识别装置 | |
CN103267867B (zh) | 一种全自动化学发光免疫分析仪 | |
CN103119450B (zh) | 将电容式接近传感结合到自动流体转移过程中的方法、系统和设备 | |
CN102147405A (zh) | 一种全自动生化免疫分析仪 | |
CN105974147A (zh) | 血型血清学自动化检测一体机 | |
CN109900892A (zh) | 一种医用转盘式多项目荧光免疫分析仪 | |
CN108957022B (zh) | 基于蛋白芯片的样品检测装置及方法 | |
JP6851079B2 (ja) | 多重反応並行測定装置およびその方法 | |
CN206146952U (zh) | 磁微粒化学发光免疫分析仪样本系统 | |
CN204255955U (zh) | 一种蛋白芯片全自动化高通量分析装置 | |
CN103196899B (zh) | 全自动高通量联合检测化学发光分析仪 | |
KR102351654B1 (ko) | 자성비드를 이용한 면역반응 분석방법 | |
CN111323411B (zh) | 一种多项目联合化学发光即时检测系统 | |
CN208902747U (zh) | 基于蛋白芯片的样品检测装置 | |
CN212008321U (zh) | 一种一体化多功能快速检测设备 | |
CN1743845A (zh) | 一种蛋白芯片的检测方法 | |
CN111458530A (zh) | 一种干式免疫分析仪加样装置 | |
CN203164125U (zh) | 全自动高通量联合检测化学发光分析仪 | |
CN111141714A (zh) | 一种一体化多功能快速检测设备 | |
CN205816308U (zh) | 一种清洗装置及全自动发光免疫分析仪 | |
CN204086274U (zh) | 一种时间分辨荧光免疫分析仪 | |
CN115366087A (zh) | 一种荧光免疫分析仪用混匀机械臂 | |
CN113188874A (zh) | 一种全自动荧光染色仪 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
PB01 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
CB03 | Change of inventor or designer information |
Inventor after: Zhang Lihai Inventor after: Chen Shuai Inventor after: Dong Liying Inventor after: Shao Wei Inventor after: Zhang Meng Inventor after: Wang Xiaofeng Inventor after: Liu Juanjuan Inventor before: Zhang Lihai Inventor before: Chen Shuai Inventor before: Shao Wei Inventor before: Zhang Meng Inventor before: Wang Xiaofeng Inventor before: Liu Juanjuan |
|
CB03 | Change of inventor or designer information | ||
GR01 | Patent grant | ||
GR01 | Patent grant |