CN108936623A - Double protein gastric cancer full nutrition formula food and preparation method thereof - Google Patents
Double protein gastric cancer full nutrition formula food and preparation method thereof Download PDFInfo
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- CN108936623A CN108936623A CN201810820029.2A CN201810820029A CN108936623A CN 108936623 A CN108936623 A CN 108936623A CN 201810820029 A CN201810820029 A CN 201810820029A CN 108936623 A CN108936623 A CN 108936623A
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- vitamin
- raw material
- calcium
- gastric cancer
- protein
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- 102000004169 proteins and genes Human genes 0.000 title claims abstract description 63
- 108090000623 proteins and genes Proteins 0.000 title claims abstract description 63
- 235000016709 nutrition Nutrition 0.000 title claims abstract description 52
- 230000035764 nutrition Effects 0.000 title claims abstract description 44
- 206010017758 gastric cancer Diseases 0.000 title claims abstract description 37
- 235000013305 food Nutrition 0.000 title claims abstract description 36
- 208000005718 Stomach Neoplasms Diseases 0.000 title claims abstract description 35
- 201000011549 stomach cancer Diseases 0.000 title claims abstract description 35
- 238000002360 preparation method Methods 0.000 title claims abstract description 17
- 229930004065 genistein derivative Natural products 0.000 claims abstract description 16
- 150000002273 genistein derivatives Chemical class 0.000 claims abstract description 16
- 150000005693 branched-chain amino acids Chemical class 0.000 claims abstract description 12
- ZDXPYRJPNDTMRX-UHFFFAOYSA-N glutamine Natural products OC(=O)C(N)CCC(N)=O ZDXPYRJPNDTMRX-UHFFFAOYSA-N 0.000 claims abstract description 12
- 239000002773 nucleotide Substances 0.000 claims abstract description 11
- 125000003729 nucleotide group Chemical group 0.000 claims abstract description 11
- ZDXPYRJPNDTMRX-VKHMYHEASA-N L-glutamine Chemical compound OC(=O)[C@@H](N)CCC(N)=O ZDXPYRJPNDTMRX-VKHMYHEASA-N 0.000 claims abstract description 9
- 150000001720 carbohydrates Chemical class 0.000 claims abstract description 7
- 235000018102 proteins Nutrition 0.000 claims description 59
- 239000002994 raw material Substances 0.000 claims description 59
- YBJHBAHKTGYVGT-ZKWXMUAHSA-N (+)-Biotin Chemical compound N1C(=O)N[C@@H]2[C@H](CCCCC(=O)O)SC[C@@H]21 YBJHBAHKTGYVGT-ZKWXMUAHSA-N 0.000 claims description 26
- AUNGANRZJHBGPY-SCRDCRAPSA-N Riboflavin Chemical compound OC[C@@H](O)[C@@H](O)[C@@H](O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-SCRDCRAPSA-N 0.000 claims description 20
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 claims description 20
- 102000004407 Lactalbumin Human genes 0.000 claims description 19
- 108090000942 Lactalbumin Proteins 0.000 claims description 19
- 238000000034 method Methods 0.000 claims description 17
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 claims description 16
- GVJHHUAWPYXKBD-UHFFFAOYSA-N (±)-α-Tocopherol Chemical compound OC1=C(C)C(C)=C2OC(CCCC(C)CCCC(C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-UHFFFAOYSA-N 0.000 claims description 16
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 claims description 16
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 16
- 108010084695 Pea Proteins Proteins 0.000 claims description 16
- 239000011575 calcium Substances 0.000 claims description 16
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- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 claims description 14
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- 239000011664 nicotinic acid Substances 0.000 claims description 14
- 235000001968 nicotinic acid Nutrition 0.000 claims description 14
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 claims description 12
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical group [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 12
- RMRCNWBMXRMIRW-BYFNXCQMSA-M cyanocobalamin Chemical compound N#C[Co+]N([C@]1([H])[C@H](CC(N)=O)[C@]\2(CCC(=O)NC[C@H](C)OP(O)(=O)OC3[C@H]([C@H](O[C@@H]3CO)N3C4=CC(C)=C(C)C=C4N=C3)O)C)C/2=C(C)\C([C@H](C/2(C)C)CCC(N)=O)=N\C\2=C\C([C@H]([C@@]/2(CC(N)=O)C)CCC(N)=O)=N\C\2=C(C)/C2=N[C@]1(C)[C@@](C)(CC(N)=O)[C@@H]2CCC(N)=O RMRCNWBMXRMIRW-BYFNXCQMSA-M 0.000 claims description 12
- 239000000463 material Substances 0.000 claims description 12
- 230000001954 sterilising effect Effects 0.000 claims description 11
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 10
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 claims description 10
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- 235000019152 folic acid Nutrition 0.000 claims description 10
- 239000011724 folic acid Substances 0.000 claims description 10
- 239000011669 selenium Substances 0.000 claims description 10
- 239000011734 sodium Substances 0.000 claims description 10
- 229910052708 sodium Inorganic materials 0.000 claims description 10
- 235000015424 sodium Nutrition 0.000 claims description 10
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims description 9
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 9
- 229910052804 chromium Inorganic materials 0.000 claims description 9
- 239000011651 chromium Substances 0.000 claims description 9
- 239000010949 copper Substances 0.000 claims description 9
- 229910052802 copper Inorganic materials 0.000 claims description 9
- 239000004615 ingredient Substances 0.000 claims description 9
- 239000011772 phylloquinone Substances 0.000 claims description 9
- 239000000843 powder Substances 0.000 claims description 9
- FPIPGXGPPPQFEQ-UHFFFAOYSA-N 13-cis retinol Natural products OCC=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-UHFFFAOYSA-N 0.000 claims description 8
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 claims description 8
- AUNGANRZJHBGPY-UHFFFAOYSA-N D-Lyxoflavin Natural products OCC(O)C(O)C(O)CN1C=2C=C(C)C(C)=CC=2N=C2C1=NC(=O)NC2=O AUNGANRZJHBGPY-UHFFFAOYSA-N 0.000 claims description 8
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 claims description 8
- CPLXHLVBOLITMK-UHFFFAOYSA-N Magnesium oxide Chemical compound [Mg]=O CPLXHLVBOLITMK-UHFFFAOYSA-N 0.000 claims description 8
- CSNNHWWHGAXBCP-UHFFFAOYSA-L Magnesium sulfate Chemical compound [Mg+2].[O-][S+2]([O-])([O-])[O-] CSNNHWWHGAXBCP-UHFFFAOYSA-L 0.000 claims description 8
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 claims description 8
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 claims description 8
- VYGQUTWHTHXGQB-FFHKNEKCSA-N Retinol Palmitate Chemical compound CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C VYGQUTWHTHXGQB-FFHKNEKCSA-N 0.000 claims description 8
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims description 8
- FPIPGXGPPPQFEQ-BOOMUCAASA-N Vitamin A Natural products OC/C=C(/C)\C=C\C=C(\C)/C=C/C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-BOOMUCAASA-N 0.000 claims description 8
- 229930003316 Vitamin D Natural products 0.000 claims description 8
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims description 8
- 229930003427 Vitamin E Natural products 0.000 claims description 8
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 8
- XLOMVQKBTHCTTD-UHFFFAOYSA-N Zinc monoxide Chemical compound [Zn]=O XLOMVQKBTHCTTD-UHFFFAOYSA-N 0.000 claims description 8
- FPIPGXGPPPQFEQ-OVSJKPMPSA-N all-trans-retinol Chemical compound OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C FPIPGXGPPPQFEQ-OVSJKPMPSA-N 0.000 claims description 8
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- WIGCFUFOHFEKBI-UHFFFAOYSA-N gamma-tocopherol Natural products CC(C)CCCC(C)CCCC(C)CCCC1CCC2C(C)C(O)C(C)C(C)C2O1 WIGCFUFOHFEKBI-UHFFFAOYSA-N 0.000 claims description 8
- 229910052742 iron Inorganic materials 0.000 claims description 8
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- 235000019796 monopotassium phosphate Nutrition 0.000 claims description 8
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- 238000005189 flocculation Methods 0.000 description 1
- 230000016615 flocculation Effects 0.000 description 1
- 239000006260 foam Substances 0.000 description 1
- 238000005187 foaming Methods 0.000 description 1
- BJHIKXHVCXFQLS-UYFOZJQFSA-N fructose group Chemical group OCC(=O)[C@@H](O)[C@H](O)[C@H](O)CO BJHIKXHVCXFQLS-UYFOZJQFSA-N 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 239000008103 glucose Substances 0.000 description 1
- 229960001031 glucose Drugs 0.000 description 1
- 235000001727 glucose Nutrition 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 235000013922 glutamic acid Nutrition 0.000 description 1
- 239000004220 glutamic acid Substances 0.000 description 1
- 238000000227 grinding Methods 0.000 description 1
- 230000002209 hydrophobic effect Effects 0.000 description 1
- 125000001165 hydrophobic group Chemical group 0.000 description 1
- 208000026278 immune system disease Diseases 0.000 description 1
- 102000018358 immunoglobulin Human genes 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 210000003734 kidney Anatomy 0.000 description 1
- 230000002147 killing effect Effects 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 229920005610 lignin Polymers 0.000 description 1
- 238000011866 long-term treatment Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 235000004213 low-fat Nutrition 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 229960003390 magnesium sulfate Drugs 0.000 description 1
- 230000001071 malnutrition Effects 0.000 description 1
- 235000000824 malnutrition Nutrition 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 230000009061 membrane transport Effects 0.000 description 1
- 230000002503 metabolic effect Effects 0.000 description 1
- WSFSSNUMVMOOMR-NJFSPNSNSA-N methanone Chemical compound O=[14CH2] WSFSSNUMVMOOMR-NJFSPNSNSA-N 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 238000012544 monitoring process Methods 0.000 description 1
- 235000019691 monocalcium phosphate Nutrition 0.000 description 1
- 210000003205 muscle Anatomy 0.000 description 1
- 239000002417 nutraceutical Substances 0.000 description 1
- 235000021436 nutraceutical agent Nutrition 0.000 description 1
- 235000018343 nutrient deficiency Nutrition 0.000 description 1
- 208000015380 nutritional deficiency disease Diseases 0.000 description 1
- 230000000050 nutritive effect Effects 0.000 description 1
- 230000008520 organization Effects 0.000 description 1
- 230000036542 oxidative stress Effects 0.000 description 1
- 230000035479 physiological effects, processes and functions Effects 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 235000021003 saturated fats Nutrition 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 150000005846 sugar alcohols Chemical class 0.000 description 1
- 239000013589 supplement Substances 0.000 description 1
- 239000000375 suspending agent Substances 0.000 description 1
- 230000002195 synergetic effect Effects 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 230000017105 transposition Effects 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 235000021122 unsaturated fatty acids Nutrition 0.000 description 1
- 150000004670 unsaturated fatty acids Chemical class 0.000 description 1
- MECHNRXZTMCUDQ-RKHKHRCZSA-N vitamin D2 Chemical compound C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)/C=C/[C@H](C)C(C)C)=C\C=C1\C[C@@H](O)CCC1=C MECHNRXZTMCUDQ-RKHKHRCZSA-N 0.000 description 1
- 235000021241 α-lactalbumin Nutrition 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/40—Complete food formulations for specific consumer groups or specific purposes, e.g. infant formula
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/30—Foods or foodstuffs containing additives; Preparation or treatment thereof containing carbohydrate syrups; containing sugars; containing sugar alcohols, e.g. xylitol; containing starch hydrolysates, e.g. dextrin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/115—Fatty acids or derivatives thereof; Fats or oils
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/125—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives containing carbohydrate syrups; containing sugars; containing sugar alcohols; containing starch hydrolysates
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/13—Nucleic acids or derivatives thereof
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
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- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/15—Vitamins
- A23L33/155—Vitamins A or D
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
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- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
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- A23L33/17—Amino acids, peptides or proteins
- A23L33/175—Amino acids
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- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/17—Amino acids, peptides or proteins
- A23L33/185—Vegetable proteins
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- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
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Abstract
The invention belongs to technical field of nutritional food, and in particular to a kind of double protein gastric cancer full nutrition formula food and preparation method thereof.Contain albumen, fat, carbohydrate, vitamin, minerals, glutamine, branched-chain amino acid, EPA, genistein derivative, nucleotide nutrient element in the double protein gastric cancer full nutrition formula food.The combination of animals and plants double protein in the present invention not only improves flavor, character and the quality of product, also reduces cost.The present invention can provide sufficient, comprehensive nutrition for body, enhance the barrier function of stomach lining, be conducive to body protein synthesis and Metabolism regulation, and stomach function and form is promoted to restore.
Description
Technical field
The invention belongs to technical field of nutritional food, and in particular to a kind of double protein gastric cancer full nutrition formula food and its system
Preparation Method.
Background technique
Double protein is that a kind of nutrition is balanced, is easy to the novel protein of absorption.With the proposition of double protein strategy, China is honest
Push the healthy product that wide animal protein and vegetable protein combine.Currently, double protein in dairy products using more, but
In special medical full nutrition formula food using less.Two kinds of animal/vegetable proteins are mutually compound, the two can be made to take length mutually
Mend it is short, battalion value significantly improving, be supplement nutrient protein health selection, the flavor and state of product are improved, so that product
Nutrition is comprehensive, bright characteristic.
Show that gastric cancer is as Digestive according to the statistics of the World Health Organization and China's tumour registration annual report data in 2012
The system highest malignant tumour of disease incidence, disease incidence occupy the 2nd, and the death rate occupies the 3rd.2012, China's mortality of gastric carcinoma
32.5 ten thousand people of case, the death rate are 21.9/10 ten thousand.
Patients with gastric cancer is mostly with different degrees of malnutrition or immune dysfunction, especially implementation radical operation for carcinoma of stomach
Patient, it is postoperative to be influenced easily to lead to nutritional deficiency by factors such as fasting, gastrointestinal decompressions.And dietetic nutrition is to sustain life, protect
The material base of health is held, largely diet has important influence to the function and state of body.Low-income earner or warp
Ji situation is not good enough person is because economic capability is limited, in the case where that can not use more efficient treatment means and drug condition, with greater need for abundance
Nutrition assurance cope with long-term treatment or rehabilitation.And currently, the full nutrition reasonable, competitively priced for patients with gastric cancer nutrition
Formula food is fewer and fewer.Therefore, developing a kind of double protein gastric cancer full nutrition formula food has great economic benefit and society
It can meaning.
Summary of the invention
The object of the present invention is to provide a kind of double protein gastric cancer full nutrition formula foods, can provide for body sufficient, complete
The nutrition in face enhances the barrier function of stomach lining, is conducive to body protein synthesis and Metabolism regulation, promotes stomach function and shape
State is restored;Present invention simultaneously provides preparation methods.
Double protein gastric cancer full nutrition formula food of the present invention, nutritional ingredient is such as in every hectogram full nutrition formula food
Under: albumen 33.5-58.3g, fat 1.3-4g, carbohydrate 34.4-60.4g, vitamin A 168-800 μ g, vitamin D
5-13 μ g, vitamin E 1.5-5mg, vitamin K118-185 μ g, vitamin B10.33-1mg, vitamin B2 0.35-1mg、
Vitamin B60.36-1mg, vitamin B120.5-20 μ g, niacin 0.83-8.9mg, folic acid 88-938 μ g, pantothenic acid 1.16-
20mg, vitamin C 2-7mg, biotin 8.3-85 μ g, sodium 45-60mg, potassium 85-145mg, copper 182-230 μ g, magnesium 73-
100mg, iron 3.3-9.4mg, zinc 1.7-8.5mg, manganese 0.099-1.2mg, calcium 215-222mg, phosphorus 159-164mg, iodine 25-50 μ
G, selenium 13-91 μ g, chromium 7-28 μ g, glutamine 18-65mg, branched-chain amino acid 70-156mg, EPA 20-50mg, genistein
Derivative 25-35mg, nucleotide 100-160mg.
Wherein:
The raw material of albumen is selected from the double protein of pea protein and lactalbumin composition;
The raw material of fat is selected from one of edible vegetable oil or a variety of;It is preferred that soybean oil, rapeseed oil, peanut oil, corn
One of oil, safflower oil or Purple Perilla Seed Oil are a variety of;
It is fine that the raw material of carbohydrate is selected from fructose, antierythrite, laminarin, maltodextrin, hydroxypropul starch, diet
One of dimension or resistant starch are a variety of;The preferred pea dietary fiber of dietary fiber, the preferred pea resistant starch of resistant starch.
The raw material of vitamin A is selected from one of retinol acetate, retinyl palmitate or beta carotene or a variety of;
The raw material of vitamin D is selected from vitamin D2Or vitamin D3One or both of;
The raw material of vitamin E is in D- alpha-tocotrienol, dl- alpha-tocotrienol or VE succinic acid calcium
It is one or more;The preferred dl- α-tocopherol acetate trienol of dl- alpha-tocotrienol;
Vitamin B1Raw material be selected from one or both of thiamine hydrochloride or Thiamin mononitrate;
Vitamin B2Raw material be selected from one or both of riboflavin or riboflavin 5 '-sodium phosphate;
Vitamin B6Raw material be selected from puridoxine hydrochloride;
Vitamin B12Raw material be selected from cyanocobalamin;
The raw material of niacin is selected from one or both of niacin or niacinamide;
The raw material of pantothenic acid is selected from D-VB5 calcium;
Ascorbic raw material is selected from L-AA, L-AA sodium, L-AA calcium or vitamin-c palmitate
One of ester is a variety of;
The raw material of biotin is selected from D-Biotin.
The raw material of sodium is selected from sodium chloride;
The raw material of potassium is selected from one of dipotassium hydrogen phosphate, potassium dihydrogen phosphate, potassium chloride or potassium citrate or a variety of;
The raw material of copper is selected from one or both of copper sulphate or copper gluconate;
The raw material of magnesium is selected from one of magnesium carbonate, magnesium sulfate, magnesia, magnesium chloride or L- magnesium threonate or a variety of;
The raw material of iron is in ferrous gluconate, ferrous fumarate, ferrous sulfate, ferrous lactate or ferrous succinate
It is one or more;
The raw material of zinc is selected from one of zinc sulfate, zinc citrate, zinc gluconate, zinc oxide or zinc lactate or a variety of;
The raw material of manganese is selected from one or both of manganese sulfate or manganese gluconate;
The raw material of calcium be selected from calcium carbonate, calcium acetate, calcium chloride, calcium citrate, calcium gluconate, calcium lactate, calcium monohydrogen phosphate,
One of calcium dihydrogen phosphate, tricalcium phosphate, calcium sulfate, L-calcium lactate or calcium glycerophosphate are a variety of;
The raw material of phosphorus is selected from potassium dihydrogen phosphate;
The raw material of iodine is selected from Potassiumiodate;
The raw material of selenium is selected from one of sodium selenite, Se-enriched yeast or L- selenium-methyl selenium substituted aminothiopropionic or a variety of;
The raw material of chromium is selected from chromium chloride.
Double protein of the present invention the preparation method comprises the following steps: pea protein is mixed with lactalbumin 1:1-1.1 in mass ratio, formed
Material, material obtain double protein after pulverizing technique, micronized process.
Wherein: pulverizing technique are as follows: in stream pressure be 0.70-1.0MPa, gas flow temperature is 10-15 DEG C of condition
Under, it is 5-8 by crushing material to granularity that the variable-frequency motor revolving speed for controlling air-stream type ultrafine pulverizer, which is 14500-16500r/min,
μm protein powder;
Micronized technique are as follows: protein powder is made into the protein dispersion that concentration is 0.08-0.12g/mL, at 85-95 DEG C
After humid heat treatment 25-35min, uses revolving speed to emulsify cutter for the high speed of 10000-15000r/min and handle 2-5min.
Genistein derivative of the present invention the preparation method comprises the following steps: by 1mmol genistein, 25mL dehydrated alcohol, 0.08mL
After 37% formaldehyde, 1mmoL 1- (2,4- 3,5-dimethylphenyl) piperazine dissolve by heating, reaction is stirred at room temperature, uses thin-layered chromatography
(TLC) degree of monitoring reaction, after reaction by recrystallization and silica gel column chromatography, the crystal for isolating and purifying precipitation is to contaminate
Expect modified lignin.
Double protein gastric cancer full nutrition formula food of the present invention the preparation method is as follows: with the full nutrition of double protein gastric cancer
100 grams of formula food quality meters, by albumen, carbohydrate, vitamin A, vitamin D, vitamin E, vitamin K1, vitamin
B1, vitamin B2, vitamin B6, vitamin B12, niacin, folic acid, pantothenic acid, vitamin C, biotin, sodium, potassium, copper, magnesium, iron, zinc,
Manganese, calcium, phosphorus, iodine, selenium, chromium, glutamine, branched-chain amino acid, EPA, genistein derivative, nucleotide nutrient ingredient raw material
After sterilizing, 5 parts are divided into, forms function bag;
After the raw material sterilizing of lipid nutrition ingredient, 5 parts are divided into, energy bag is formed.
Wherein: sterilizing power is 425-500W, sterilization time 100-120s.
The eating method of double protein gastric cancer full nutrition formula food of the present invention is as follows:
The age of target group is 18-64 years old, does not include pregnant woman and breast feeding women;
Dosage are as follows: 0.4 bag/(kgd), total amount is no more than 27 bags;
It is edible according to one of following two method:
(1) it is cooled to 40-60 DEG C with the boiled water of 100-200mL, the nutriment in function bag and energy bag is added, stirs
After mixing, shaking up, directly drinks or taken in through tube feed;
(2) nutriment in function bag is added in the diet without containing salt and is eaten, contained in diet
Some fat is consistent with the fat content in energy bag.
The marketing method of product of the present invention is to be distributed directly to consumer, by the places such as hospital, supermarket or pharmacy or
The characteristics of approach is cut down the number of intermediate links, and is reduced expense, is realized low price sale with small profits, the food that consumer can be more economical, more economical
With meeting the edible requirement of long term consumer.
Beneficial effects of the present invention are as follows:
The effect of double protein gastric cancer full nutrition formula food of the present invention depends on each self-applying and to each other of nutritional ingredient
Synergistic effect.
In the present invention, lactalbumin is good protein, contains beta lactoglobulin, α-lactalbumin, immunoglobulin etc.
A variety of active ingredients;Fat, the content of lactose are low in lactalbumin, and saturated fat that more other animal protein contain, gallbladder are solid
The harmful substances such as alcohol are few, it is necessary to which amino acid classes and content are complete, and nutritive value is high, is easily digested absorption, can enhance immune, energy
Prevent blood lipid and cholesterol from increasing, it is beneficial to cardiovascular disease.
Compared with animal protein, pea protein has reduction cholesterol, prevents cardiovascular disease, is antitumor, reducing kidney
The effects of disease incidence, is more advantageous to human health.Glutamic acid rich in, arginine, are respectively provided with muscle in pea protein
Restore the effect with cardiovascular disease prevention.In addition, pea protein is cheap, but its mouthfeel is bad, has fishy smell, and molten
Solution property is bad.Lactalbumin has the advantages that mouthfeel is good, dissolubility is good, but its price is higher.Pea protein is used in formula
With the form of lactalbumin double protein, both vegetable protein and animal protein advantage are combined, avoids the deficiency of single albumen,
Cost of material is reduced again.
Importantly, the absorbability of lactalbumin is stronger than pea protein, and lactalbumin is easier to send out compared to pea protein
Raw carbonylation, carbonylation will affect the structure and function of protein, to influence the color of product, flavor, physics and chemistry
Quality and functional characteristic.In order to avoid carbonylation occurs for lactalbumin, the present invention is double using pea protein and lactalbumin
The compound form of albumen, by adding pea protein, when so that carbonylation occurring for lactalbumin in following process, pea egg
It is white that lactalbumin is played a certain protective role.
Pea protein and lactalbumin improve specific surface area, surface energy and the hole of protein body after pulverizing
Rate, to increase the contact area of protein body and oil, oil absorption is significantly improved.Ultramicro grinding leads to active site of protein hydrophobic group
Group's exposure, the enhancing of albumen hydrophobicity, emulsibility and emulsion stability improve;Simultaneously segment it is flexible increase and hydrophobic grouping,
The abundant exposure of polar group and-SH increases the foaming characteristic and foam stability of albumen.Therefore, the present invention utilizes Ultramicro-powder
Broken process pea protein and lactalbumin, so that double protein has better functional character and dissolubility.
The raw material of fat is selected from rich in the soybean oil, rapeseed oil, peanut oil, corn oil, red based on unsaturated fatty acid
One of caul-fat or Purple Perilla Seed Oil are a variety of, are aided with omega-3 polyunsaturated fatty acids, EPA etc..This collocation can sufficiently be sent out
Waving omega-3 polyunsaturated fatty acids improves membrane structure, improves cell membrane transport and immune function, promotes T lymphocyte immune
Mature effect;Addition nucleotide participates in all activities of internal cell, increases lymphocytes in blood number, and enhancing lymph is thin
Born of the same parents' function improves the body immunity of eater;In addition, these oil by it is reasonably combined it is cheap, be easy to get, fatty acid
Composition meets specific medical food requirement.
Antierythrite can improve the mouthfeel of diet, improve the appetite of patient, and reducing chemotherapy influences the anorexia of patient, food
The depressed mood of patient can be improved after, while combining adjusting stomach with pea dietary fiber, resistant starch, reduce chemotherapy
The problems such as bring defecation is unsmooth.Hydroxypropul starch is good suspending agent, and suspending effect is good, does not glue wall, easily disperses, flocculation
Grain is fine and smooth.Maltodextrin has good dissolubility, can improve the mobility of product.
Glutamine has significant auxiliary therapeutic action to chemotherapy of gastric cancer patient, while can reduce the side effect of chemotherapy.It is logical
Too strong inoxidizability selective clearing free radical, reservation can have the superoxide ion of killing effect certainly to stomach cancer cell from the root
By base, in addition, oxidative stress status is adjusted, can also to improve ADA, GSH in Plasma of Patient With Gastric Cancer, PX, CAT, SOD,
The expression of MDA, so that the physical condition of patient is adjusted, the deterioration or recurrence for being conducive to the rehabilitation of patient, avoiding disease.
EPA can enhance parenteral absorption, improve the immune function of late gastric cancer patients undergoing chemotherapy, protect the immune of stomach lining
Barrier, effect are obvious;Branched-chain amino acid is conducive to maintain the nutrition condition of patient, reduces complication rate, improves patient's
Compliance is treated, its quality of life can be improved compared with unsupplemented patient.Genistein derivative itself, which has, inhibits stomach to burst
The effect of ulcer and stomach cancer cell, addition genistein derivative is conducive to assist in the treatment of stomach cancer in product.
High protein of the present invention, low fat formula meet gastric cancer eater's physical feature, are conducive to physical rehabilitation.Of the invention
Nutraceutical for body other than it can provide sufficient, comprehensive nutrition, it is often more important that enhance the barrier function of stomach lining, more
Meet metabolic physiology state, be conducive to body protein synthesis and Metabolism regulation, promotes stomach function and form to restore, prevent bacterium
With toxin transposition, hence it is evident that the generation for reducing stomach source sexuality dye is the effective means for improving patients undergoing chemotherapy nutrition condition.The present invention couple
The nutrition condition of advanced gastric carcinoma patients undergoing chemotherapy can play certain improvement result, reduce patient's adverse reaction, can effectively mention
The immunity of high patient.In addition, in the present invention animals and plants double protein combination, not only improve flavor, character and the product of product
Matter also reduces cost, also is compliant with the policy of the new and old kinetic energy conversion of country.
Specific embodiment
The present invention is described further with reference to embodiments.
Embodiment 1
Nutritional ingredient is as follows in every hectogram double protein gastric cancer full nutrition formula food: protein 42 g, fat 4g, carbon hydrate
Object 51.5g, 240.79 μ g of vitamin A, 5 μ g of vitamin D, vitamin E 1.6mg, vitamin K119 μ g, vitamin B1
0.4mg, vitamin B20.5mg, vitamin B60.6mg, vitamin B121 μ g, niacin 0.95mg, 325 μ g of folic acid, pantothenic acid
10.8mg, vitamin C 3mg, 85 μ g of biotin, sodium 53.07mg, potassium 99.41mg, 200 μ g of copper, magnesium 73.2mg, iron 4.28mg,
Zinc 5.2mg, manganese 0.65mg, calcium 216mg, phosphorus 160.01mg, 29.67 μ g of iodine, 24.2 μ g of selenium, 7.82 μ g of chromium, glutamine 18mg,
Branched-chain amino acid 70mg, EPA 20mg, genistein derivative 25mg, nucleotide 100mg.
The raw material for preparing every hectogram full nutrition formula food is as follows:
It is double protein 42g, soybean oil 1g, safflower oil 3g, fructose 30g, pea dietary fiber 10g, hydroxypropul starch 10g, red
Moss sugar alcohol 1.5g, 240.79 μ g of retinol acetate, vitamin D25 μ g, D- alpha-tocotrienol 1.6mg, vitamin K1 19μg、
400 μ g of thiamine hydrochloride, 500 μ g of riboflavin, 600 μ g of puridoxine hydrochloride, 1 μ g of cyanocobalamin, 950 μ g of niacin, 325 μ g of folic acid, D-
Calcium pantothenate 23.47mg, L-AA 3mg, 85 μ g of D-Biotin, sodium chloride 135mg, potassium citrate 260mg, copper sulphate
502.39 μ g, magnesia 122mg, ferrous fumarate 13mg, zinc oxide 6.47mg, manganese sulfate 1.78mg, calcium citrate 895mg,
Potassium dihydrogen phosphate 703mg, 50 μ g of Potassiumiodate, 53 μ g of sodium selenite, 40 μ g of chromium chloride, glutamine 18mg, branched-chain amino acid
70mg, EPA 20mg, genistein derivative 25mg, nucleotide 100mg.
Wherein:
Double protein the preparation method comprises the following steps: 20g pea protein is mixed with 22g lactalbumin, material is formed, in stream pressure
For 1.0MPa, under conditions of gas flow temperature is 15 DEG C, the variable-frequency motor revolving speed for controlling air-stream type ultrafine pulverizer is 16500r/
Min, the protein powder for being 8 μm by crushing material to granularity;Protein powder is made into the protein dispersion that concentration is 0.10g/mL,
After 90 DEG C of humid heat treatment 30min, uses revolving speed to emulsify cutter for the high speed of 15000r/min and handle 2min, obtain egg-pair
It is white.
Genistein derivative the preparation method comprises the following steps: by 1mmol genistein, 25mL dehydrated alcohol, 37% first of 0.08mL
After aldehyde, 1mmoL 1- (2,4- 3,5-dimethylphenyl) piperazine dissolve by heating, reaction is stirred at room temperature, is monitored with thin-layered chromatography (TLC)
The degree of reaction, after reaction by recrystallization and silica gel column chromatography, the crystal for isolating and purifying precipitation is that genistein spreads out
Biology.
The preparation method is as follows:
By double protein, fructose, dietary fiber, hydroxypropul starch, antierythrite, retinol acetate, vitamin D2, D- α-life
Educate trienol, vitamin K1, thiamine hydrochloride, riboflavin, puridoxine hydrochloride, cyanocobalamin, niacin, folic acid, D-VB5 calcium, L- it is anti-
Bad hematic acid, D-Biotin, sodium chloride, potassium citrate, copper sulphate, magnesia, ferrous fumarate, zinc oxide, manganese sulfate, citric acid
Calcium, potassium dihydrogen phosphate, Potassiumiodate, sodium selenite, chromium chloride, glutamine, branched-chain amino acid, EPA, genistein derivative,
Nucleotide, sterilize 100s in the sterilizer of 500W, after sterilizing, is divided into 5 parts, forms function bag;
Soybean oil, safflower oil are sterilized 100s in the sterilizer of 500W, after sterilizing, 5 parts is divided into, forms energy
Bag.
Embodiment 2
Nutritional ingredient is as follows in every hectogram double protein gastric cancer full nutrition formula food: albumen 40g, fat 2g, carbon hydrate
Object 55g, 287.79 μ g of vitamin A, 10 μ g of vitamin D, vitamin E 1.5mg, vitamin K125 μ g, vitamin B1
0.45mg, vitamin B20.6mg, vitamin B60.6mg, vitamin B120.5 μ g, niacin 1mg, 200 μ g of folic acid, pantothenic acid
2.52mg, vitamin C 5mg, 19 μ g of biotin, sodium 56.61mg, potassium 108.6mg, 190.31 μ g of copper, magnesium 80mg, iron 4.28mg,
Zinc 7.43mg, 100.13 μ g of manganese, calcium 216mg, phosphorus 160.01mg, 35.604 μ g of iodine, 45.7 μ g of selenium, 16.42 μ g of chromium, glutamine
65mg, branched-chain amino acid 156mg, EPA 50mg, genistein derivative 35mg, nucleotide 160mg.
The raw material for preparing every hectogram full nutrition formula food is as follows:
Double protein 40g, Purple Perilla Seed Oil 1g, corn oil 1g, fructose 10g, pea dietary fiber 10g, laminarin 5g, hydroxypropyl
Base starch 10g, pea resistant starch 10g, antierythrite 10g, 287.79 μ g of retinyl palmitate, vitamin D3 10μg、dl-
α-tocopherol acetate trienol 6mg, vitamin K125 μ g, 450 μ g of Thiamin mononitrate, 600 μ g of riboflavin, 600 μ of puridoxine hydrochloride
G, 0.5 μ g of cyanocobalamin, 1000 μ g of niacin, 200 μ g of folic acid, D-VB5 calcium 5.47mg, ascorbyl palmitate 5mg, D- biology
19 μ g of element, sodium chloride 144mg, potassium citrate 284mg, copper gluconate 1.35mg, magnesium sulfate 396.16mg, ferrous fumarate
13mg, zinc lactate 27.67mg, 275.21 μ g of manganese sulfate, L-calcium lactate 1661mg, potassium dihydrogen phosphate 703mg, 60 μ g of Potassiumiodate,
100 μ g of sodium selenite, 84 μ g of chromium chloride, glutamine 65mg, branched-chain amino acid 156mg, EPA 50mg, genistein derivative
35mg, nucleotide 160mg.
Wherein:
Double protein the preparation method comprises the following steps: 20g pea protein is mixed with 20g lactalbumin, material is formed, in stream pressure
For 0.7MPa, under conditions of gas flow temperature is 10 DEG C, the variable-frequency motor revolving speed for controlling air-stream type ultrafine pulverizer is 14500r/
Min, the protein powder for being 5 μm by crushing material to granularity;Protein powder is made into the protein dispersion that concentration is 0.12g/mL,
After 95 DEG C of humid heat treatment 35min, uses revolving speed to emulsify cutter for the high speed of 10000r/min and handle 5min, obtain egg-pair
It is white.
Genistein derivative the preparation method comprises the following steps: by 1mmol genistein, 25mL dehydrated alcohol, 37% first of 0.08mL
After aldehyde, 1mmoL 1- (2,4- 3,5-dimethylphenyl) piperazine dissolve by heating, reaction is stirred at room temperature, is monitored with thin-layered chromatography (TLC)
The degree of reaction, after reaction by recrystallization and silica gel column chromatography, the crystal for isolating and purifying precipitation is that genistein spreads out
Biology.
The preparation method is as follows:
By double protein, fructose, pea dietary fiber, laminarin, hydroxypropul starch, pea resistant starch, antierythrite,
Retinyl palmitate, vitamin D3, dl- α-tocopherol acetate trienol, vitamin K1, Thiamin mononitrate, riboflavin, hydrochloric acid pyrrole tremble
Alcohol, cyanocobalamin, niacin, folic acid, D-VB5 calcium, ascorbyl palmitate, D-Biotin, sodium chloride, potassium citrate, glucose
Sour copper, magnesium sulfate, ferrous fumarate, zinc lactate, manganese sulfate, L-calcium lactate, potassium dihydrogen phosphate, Potassiumiodate, sodium selenite, chlorination
Chromium, glutamine, branched-chain amino acid, EPA, genistein derivative, nucleotide, sterilize 100s in the sterilizer of 500W, goes out
After bacterium, 5 parts are divided into, forms function bag;
Purple Perilla Seed Oil, corn oil are sterilized 100s in the sterilizer of 500W, after sterilizing, 5 parts is divided into, forms energy
Bag.
Claims (10)
1. a kind of double protein gastric cancer full nutrition formula food, it is characterised in that nutritional ingredient is such as in every hectogram full nutrition formula food
Under: albumen 33.5-58.3g, fat 1.3-4g, carbohydrate 34.4-60.4g, vitamin A 168-800 μ g, vitamin D
5-13 μ g, vitamin E 1.5-5mg, vitamin K118-185 μ g, vitamin B10.33-1mg, vitamin B2 0.35-1mg、
Vitamin B60.36-1mg, vitamin B120.5-20 μ g, niacin 0.83-8.9mg, folic acid 88-938 μ g, pantothenic acid 1.16-
20mg, vitamin C 2-7mg, biotin 8.3-85 μ g, sodium 45-60mg, potassium 85-145mg, copper 182-230 μ g, magnesium 73-
100mg, iron 3.3-9.4mg, zinc 1.7-8.5mg, manganese 0.099-1.2mg, calcium 215-222mg, phosphorus 159-164mg, iodine 25-50 μ
G, selenium 13-91 μ g, chromium 7-28 μ g, glutamine 18-65mg, branched-chain amino acid 70-156mg, EPA 20-50mg, genistein
Derivative 25-35mg, nucleotide 100-160mg.
2. double protein gastric cancer full nutrition formula food according to claim 1, it is characterised in that:
The raw material of albumen is selected from the double protein of pea protein and lactalbumin composition;
The raw material of fat is selected from one of edible vegetable oil or a variety of;
The raw material of carbohydrate be selected from fructose, antierythrite, laminarin, maltodextrin, hydroxypropul starch, dietary fiber or
One of resistant starch is a variety of.
3. double protein gastric cancer full nutrition formula food according to claim 1, it is characterised in that:
The raw material of vitamin A is selected from one of retinol acetate, retinyl palmitate or beta carotene or a variety of;
The raw material of vitamin D is selected from vitamin D2Or vitamin D3One or both of;
The raw material of vitamin E is selected from one of D- alpha-tocotrienol, dl- alpha-tocotrienol or VE succinic acid calcium
Or it is a variety of;
Vitamin B1Raw material be selected from one or both of thiamine hydrochloride or Thiamin mononitrate;
Vitamin B2Raw material be selected from one or both of riboflavin or riboflavin 5 '-sodium phosphate;
Vitamin B6Raw material be selected from puridoxine hydrochloride;
Vitamin B12Raw material be selected from cyanocobalamin;
The raw material of niacin is selected from one or both of niacin or niacinamide;
The raw material of pantothenic acid is selected from D-VB5 calcium;
Ascorbic raw material is in L-AA, L-AA sodium, L-AA calcium or ascorbyl palmitate
It is one or more;
The raw material of biotin is selected from D-Biotin.
4. double protein gastric cancer full nutrition formula food according to claim 1, it is characterised in that:
The raw material of sodium is selected from sodium chloride;
The raw material of potassium is selected from one of dipotassium hydrogen phosphate, potassium dihydrogen phosphate, potassium chloride or potassium citrate or a variety of;
The raw material of copper is selected from one or both of copper sulphate or copper gluconate;
The raw material of magnesium is selected from one of magnesium carbonate, magnesium sulfate, magnesia, magnesium chloride or L- magnesium threonate or a variety of;
The raw material of iron is selected from one of ferrous gluconate, ferrous fumarate, ferrous sulfate, ferrous lactate or ferrous succinate
Or it is a variety of;
The raw material of zinc is selected from one of zinc sulfate, zinc citrate, zinc gluconate, zinc oxide or zinc lactate or a variety of;
The raw material of manganese is selected from one or both of manganese sulfate or manganese gluconate;
The raw material of calcium is selected from calcium carbonate, calcium acetate, calcium chloride, calcium citrate, calcium gluconate, calcium lactate, calcium monohydrogen phosphate, phosphoric acid
One of calcium dihydrogen, tricalcium phosphate, calcium sulfate, L-calcium lactate or calcium glycerophosphate are a variety of;
The raw material of phosphorus is selected from potassium dihydrogen phosphate;
The raw material of iodine is selected from Potassiumiodate;
The raw material of selenium is selected from one of sodium selenite, Se-enriched yeast or L- selenium-methyl selenium substituted aminothiopropionic or a variety of;
The raw material of chromium is selected from chromium chloride.
5. double protein gastric cancer full nutrition formula food according to claim 2, it is characterised in that: the preparation method of double protein
Are as follows: pea protein is mixed with lactalbumin 1:1-1.1 in mass ratio, forms material, material is through pulverizing technique, micronized
Double protein is obtained after process.
6. double protein gastric cancer full nutrition formula food according to claim 5, it is characterised in that:
Pulverize technique are as follows: stream pressure be 0.70-1.0MPa, gas flow temperature be 10-15 DEG C under conditions of, control air-flow
The variable-frequency motor revolving speed of formula micronizer is 14500-16500r/min, the albumen powder for being 5-8 μm by crushing material to granularity
Body;
Micronized technique are as follows: protein powder is made into the protein dispersion that concentration is 0.08-0.12g/mL, it is damp and hot at 85-95 DEG C
After handling 25-35min, uses revolving speed to emulsify cutter for the high speed of 10000-15000r/min and handle 2-5min.
7. a kind of preparation method of double protein gastric cancer full nutrition formula food described in claim 1, it is characterised in that: with egg-pair
White 100 grams of gastric cancer full nutrition formula food quality meters, by albumen, carbohydrate, vitamin A, vitamin D, vitamin E, dimension
Raw element K1, vitamin B1, vitamin B2, vitamin B6, vitamin B12, niacin, folic acid, pantothenic acid, vitamin C, biotin, sodium,
Potassium, copper, magnesium, iron, zinc, manganese, calcium, phosphorus, iodine, selenium, chromium, glutamine, branched-chain amino acid, EPA, genistein derivative, nucleosides
After the raw material sterilizing of sour nutritional ingredient, 5 parts are divided into, function bag is formed;
After the raw material sterilizing of lipid nutrition ingredient, 5 parts are divided into, energy bag is formed.
8. the preparation method of double protein gastric cancer full nutrition formula food according to claim 7, it is characterised in that: sterilizing function
Rate is 425-500W, sterilization time 100-120s.
9. a kind of eating method of double protein gastric cancer full nutrition formula food described in claim 1, it is characterised in that:
The age of target group is 18-64 years old, does not include pregnant woman and breast feeding women;
Dosage are as follows: 0.4 bag/(kgd), total amount is no more than 27 bags;
It is edible according to one of following two method:
(1) it is cooled to 40-60 DEG C with the boiled water of 100-200mL, the nutriment in function bag and energy bag is added, stirs, shake
After even, directly drink or taken in through tube feed;
(2) nutriment in function bag is added in the diet without containing salt and is eaten, contained in diet
Fat is consistent with the fat content in energy bag.
10. a kind of marketing method of double protein gastric cancer full nutrition formula food described in claim 1, it is characterised in that: sale
Mode is to be distributed directly to consumer not by hospital, supermarket or pharmacy.
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CN112262982A (en) * | 2020-10-22 | 2021-01-26 | 刘昌峨 | Functional food for assisting in repairing digestive tract mucosa after chemotherapy and application thereof |
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