CN108929781A - A kind of preparation method of eucalyptol - Google Patents
A kind of preparation method of eucalyptol Download PDFInfo
- Publication number
- CN108929781A CN108929781A CN201710383033.2A CN201710383033A CN108929781A CN 108929781 A CN108929781 A CN 108929781A CN 201710383033 A CN201710383033 A CN 201710383033A CN 108929781 A CN108929781 A CN 108929781A
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- CN
- China
- Prior art keywords
- eucalyptol
- under reduced
- reduced pressure
- concentrated under
- preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/02—Recovery or refining of essential oils from raw materials
- C11B9/022—Refining
-
- C—CHEMISTRY; METALLURGY
- C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
- C11B—PRODUCING, e.g. BY PRESSING RAW MATERIALS OR BY EXTRACTION FROM WASTE MATERIALS, REFINING OR PRESERVING FATS, FATTY SUBSTANCES, e.g. LANOLIN, FATTY OILS OR WAXES; ESSENTIAL OILS; PERFUMES
- C11B9/00—Essential oils; Perfumes
- C11B9/02—Recovery or refining of essential oils from raw materials
- C11B9/025—Recovery by solvent extraction
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- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Wood Science & Technology (AREA)
- Organic Chemistry (AREA)
- Medicines Containing Plant Substances (AREA)
- Extraction Or Liquid Replacement (AREA)
Abstract
The present invention relates to a kind of preparation method of eucalyptol, processing step includes：A. folium artemisiae argyi is dry, crushes, and crosses 20 meshes；B. 4 ~ 6 times of material quality of 70 ~ 80% ethanol solution is added to be placed in ultrasound-Microwave Extraction device after impregnating 1h, ultrasonic wave 300W is set, microwave power is 300 ~ 500W, extracts 2 ~ 3h；C. it is centrifuged, gained supernatant is concentrated under reduced pressure into no alcohol taste, and ammonium hydroxide adjusts pH value to 8 ~ 9；D. eluent is concentrated under reduced pressure, and organic solvent extracts 2 times, gained extract liquor is concentrated, after vacuum drying up to eucalyptol.The present invention has many advantages, such as that simple process, extraction time are short, selectivity is high, non-hazardous to environment, is suitble to large-scale production.
Description
Technical field：
The present invention relates to a kind of preparation method of eucalyptol more particularly to a kind of utilize ultrasound-Microwave Extraction eucalyptol method.
Background technique：
Chinese mugwort, scientific name：Artemisia argyi H. L é v. & Vaniot, alias：Xiao Mao, ice platform hold back grass etc., bitter in taste, pungent,
Temperature enters spleen, liver, kidney.All herbal medicine, have Wen Jing, dry, cold dispelling, hemostasis, anti-inflammatory, relieving asthma, cough-relieving, miscarriage prevention, antiallergy etc. are made
With.
Eucalyptol, also known as（1,8-）Cineole, Cineole eucalyptus essence.Molecular formula：C10H18O, molecular weight：154.24, belong to
Monoterpenes compound.Colourless liquid, acrid flavour is cold, there is smell similar with camphor.For medicinal herbs type essence, essential oil and tooth are prepared
The essence such as cream, tooth powder, oral cavity freshener, medicated soap, are also relatively chiefly used in medicine.With antipyretic, anti-inflammatory, antibacterial, anti-corrosion, relieving asthma and town
Pain acts on.Also it is commonly used for fragrance and preservative.
It is more about the patent and document of the extraction of eucalyptol at present, mainly use solvent extraction, supercritical fluid extraction
It follows the example of or sour water percolation etc., there are many deficiencies.Supercritical extraction, disadvantage is that equipment cost is high, it is uncomfortable
It is suitable for industrialized production；Sour water percolation is industrially mostly used to extract at present, disadvantage is that cumbersome, recovery rate
It is low, waste liquid amount is big.
Summary of the invention：
In view of the deficiencies of the prior art, it is an object of the present invention to provide a kind of simple process, it is easy to operate, fast and efficiently extract
The method of eucalyptol.
The present invention includes the following steps：
A. folium artemisiae argyi is dry, crushes, and crosses 20 meshes；
B. 4 ~ 6 times of material quality of 70 ~ 80% ethanol solution is added to be placed in ultrasound-Microwave Extraction device after impregnating 1h, if
Ultrasonic wave 300W is set, microwave power is 300 ~ 500W, extracts 2 ~ 3h；
C. it is centrifuged, gained supernatant is concentrated under reduced pressure into no alcohol taste, and ammonium hydroxide adjusts pH value to 8 ~ 9；
D. eluent is concentrated under reduced pressure, and organic solvent extracts 2 times, gained extract liquor is concentrated, after vacuum drying up to eucalyptol.
Organic solvent described in step d is petroleum ether.
The present invention is further illustrated below in conjunction with specific embodiment, but the scope of protection of present invention is not limited to
In following embodiments.
Specific embodiment：
Embodiment 1：
Folium artemisiae argyi is dry, crushes, and crosses 20 meshes；4 times of material quality of 70% ethanol solution is added, after impregnating 1h, is placed in ultrasound-
In Microwave Extraction device, ultrasonic wave 300W, microwave power 300W are set, extract 2h；Centrifugation, gained supernatant are concentrated under reduced pressure into
Without alcohol taste, ammonium hydroxide adjusts pH value to 8；Eluent is concentrated under reduced pressure, and organic solvent petroleum ether extraction 2 times, gained extract liquor is concentrated,
Up to eucalyptol after vacuum drying.
Embodiment 2：
Folium artemisiae argyi is dry, crushes, and crosses 20 meshes；6 times of material quality of 80% ethanol solution is added, after impregnating 1h, is placed in ultrasound-
In Microwave Extraction device, ultrasonic wave 300W, microwave power 500W are set, extract 3h；Centrifugation, gained supernatant are concentrated under reduced pressure into
Without alcohol taste, ammonium hydroxide adjusts pH value to 9；Eluent is concentrated under reduced pressure, and organic solvent petroleum ether extraction 2 times, gained extract liquor is concentrated,
Up to eucalyptol after vacuum drying.
Embodiment 3：
Folium artemisiae argyi is dry, crushes, and crosses 20 meshes；5 times of material quality of 75% ethanol solution is added, after impregnating 1h, is placed in ultrasound-
In Microwave Extraction device, ultrasonic wave 300W, microwave power 400W are set, extract 2h；Centrifugation, gained supernatant are concentrated under reduced pressure into
Without alcohol taste, ammonium hydroxide adjusts pH value to 8；Eluent is concentrated under reduced pressure, and organic solvent petroleum ether extraction 2 times, gained extract liquor is concentrated,
Up to eucalyptol after vacuum drying.
Claims (2)
1. a kind of preparation method of eucalyptol, which is characterized in that include the following steps：
A. folium artemisiae argyi is dry, crushes, and crosses 20 meshes；
B. 4 ~ 6 times of material quality of 70 ~ 80% ethanol solution is added to be placed in ultrasound-Microwave Extraction device after impregnating 1h, if
Ultrasonic wave 300W is set, microwave power is 300 ~ 500W, extracts 2 ~ 3h；
C. it is centrifuged, gained supernatant is concentrated under reduced pressure into no alcohol taste, and ammonium hydroxide adjusts pH value to 8 ~ 9；
D. eluent is concentrated under reduced pressure, and organic solvent extracts 2 times, gained extract liquor is concentrated, after vacuum drying up to eucalyptol.
2. a kind of preparation method of eucalyptol according to claim 1, which is characterized in that the organic solvent is petroleum
Ether.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710383033.2A CN108929781A (en) | 2017-05-26 | 2017-05-26 | A kind of preparation method of eucalyptol |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201710383033.2A CN108929781A (en) | 2017-05-26 | 2017-05-26 | A kind of preparation method of eucalyptol |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108929781A true CN108929781A (en) | 2018-12-04 |
Family
ID=64451547
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201710383033.2A Pending CN108929781A (en) | 2017-05-26 | 2017-05-26 | A kind of preparation method of eucalyptol |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108929781A (en) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022199653A1 (en) * | 2021-03-26 | 2022-09-29 | 江南大学 | Method for preparing eucalyptol emulsion and application thereof in biopesticide |
-
2017
- 2017-05-26 CN CN201710383033.2A patent/CN108929781A/en active Pending
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2022199653A1 (en) * | 2021-03-26 | 2022-09-29 | 江南大学 | Method for preparing eucalyptol emulsion and application thereof in biopesticide |
| US11980186B2 (en) | 2021-03-26 | 2024-05-14 | Jiangnan University | Preparation method of eucalyptol emulsion and application thereof in biopesticides |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| WD01 | Invention patent application deemed withdrawn after publication | ||
| WD01 | Invention patent application deemed withdrawn after publication |
Application publication date: 20181204 |