CN108853449A - A kind of dysmenorrhea navel patch and preparation method thereof - Google Patents
A kind of dysmenorrhea navel patch and preparation method thereof Download PDFInfo
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/48—Reproductive organs
- A61K35/50—Placenta; Placental stem cells; Amniotic fluid; Amnion; Amniotic stem cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/286—Carthamus (distaff thistle)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/481—Astragalus (milkvetch)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/533—Leonurus (motherwort)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9068—Zingiber, e.g. garden ginger
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/70—Web, sheet or filament bases ; Films; Fibres of the matrix type containing drug
- A61K9/7023—Transdermal patches and similar drug-containing composite devices, e.g. cataplasms
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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Abstract
The present invention discloses a kind of dysmenorrhea navel patch, and effective component includes the raw material of following parts by weight：0.5-1.5 parts of deer placenta polypeptide, 0.08-0.1 parts of motherwort, 0.05-0.1 parts of safflower, 0.02-0.05 parts of baked ginger, 0.02-0.05 parts of Radix Astragali, 0.02-0.05 parts of Gui Zhi, 0.02-0.05 parts of the root of Dahurain angelica.Preparation method is provided simultaneously.Medicinal extract is made in deer placenta polypeptide, motherwort, safflower, baked ginger etc. by the present invention, then patch is made, and can be warmed up palace dredging collateral, conditioning palace cold, supplement qi and blood, is effectively improved discomfort caused by menstruation dysmenorrhea.
Description
Technical field
The present invention relates to technical field of pharmaceuticals, and in particular to a kind of dysmenorrhea navel patch and preparation method thereof.
Background technique
There is periodical underbelly pain on the occasion of menstrual period or front and back of passing through in women, or pain draws waist sacrum or even severe pain is extremely fainted
Person becomes " dysmenorrhea ", also referred to as " menalgia ".Symptoms include menstrual period or front and back lower abdominal distention pain of passing through, and with the menstrual cycle and repeatedly
Breaking-out.Fall ill in love will of dysmenorrhea is hurt, and daily life is accidentally or the six external factors which cause diseases causes harm equal different pathogenies, and with ferritic and menstrual period, pass through before and after
Special physiological environment is related.Its pathogenesis is due to caused by punching times channel is unfavorable, QI-blood circulation is unsmooth.Tcm clinical practice is dialectical
Be divided into qi depression to blood stasis, cold-dampness stagnate, dampness and heat stasis, deficient qi and blood and liver kidney deficiency damage etc. cards type.Dysmenorrhea mostly occurs in unmarried or
In the young and middle-aged women crowd of wedding.
Gynecology of Chinese Medicine has accumulated the rich experiences for the treatment of dysmenorrhea in long-term medical practice.Record in relation to dysmenorrhea,
Synopsis Golden Chamber the miscellaneous internal diseases in woman arteries and veins is seen earliest to demonstrate,prove and control：" leukorrhagia, menstrual disorders, lower abdominal pain and fullness, through goodbye in January ".Sui Dynasty《It is all
Pathogeny waits opinion》Head vertical " menstrual abdominalgia time ", it is believed that " married woman menstrual abdominalgia person, by internal lesion caused by overexertion vim and vigour, so that it is physically weak, by air-cooled
Gas visitor in collaterals of the uterus, arteries and veins that damage punching is appointed ", established theoretical basis for the research and treatment of dysmenorrhea.Later age doctor is to explore pain
The Therapy regularity of warp has made many effort.Song Dynasty famous gynaecology works《Married woman's good recipe is complete works of》" menstruation regulating door " special train " moon
Water whereabouts abdominal pain ", it is believed that air-cooled is the most important reason of dysmenorrhea, and shows the representative prescription-wenjing decoction for controlling dysmenorrhea.This Fang Weihou
One of the prescription of the most commonly used treatment dysmenorrhea of physicians from a family for generations family.《Danxi's experiential therapy》It is proposed dysmenorrhea have blood reality, stasis, hemostasis etc. because, and
It is treated by differentiation of syndromes of deficiency and excess.These instruct clinical treatment with discussing continuously effectives, can not to release that the slight illness of numerous women plays
The effect of substitution.In addition, ancient Chinese medicine doctor in long-term medical practice, has also formulated interior control（Endo-medicine）, outside control, acupuncture,
The multiple therapy methods such as massage.And endo-medicine, when drug ingedient is applied to uterine cavity, effect is substantially reduced.Acupuncture, massage etc.
It cannot fundamentally solve the problems, such as dysmenorrhea.And external therapy is one of the effective ways that ancient Chinese medicine doctor is praised highly, wherein navel therapy with
It is using easy, idicatio is wide, proving effective obtains the attention of doctor and the welcome of patient rapidly.
Summary of the invention
It is an object of that present invention to provide a kind of dysmenorrhea navel patches, while it is of the invention another for providing its corresponding preparation method
Goal of the invention.
Based on above-mentioned purpose, the present invention takes following technical scheme：
A kind of dysmenorrhea navel patch, effective component includes the raw material of following parts by weight：0.5-1.5 parts of deer placenta polypeptide, motherwort 0.08-
0.1 part, 0.05-0.1 parts of safflower, 0.02-0.05 parts of baked ginger, 0.02-0.05 parts of Radix Astragali, 0.02-0.05 parts of Gui Zhi, the root of Dahurain angelica
0.02-0.05 parts.
Dysmenorrhea navel patch, effective component includes the raw material of following parts by weight：It is 1.0 parts of deer placenta polypeptide, 0.08 part of motherwort, red
Spend 0.1 part, 0.03 part of baked ginger, 0.04 part of Radix Astragali, 0.04 part of Gui Zhi, 0.02 part of the root of Dahurain angelica.
The method for preparing dysmenorrhea navel patch, includes the following steps：
1）The production of medicinal extract：After each raw material is ground into mixed powder by corresponding proportion, it is added to the water immersion, boils, obtain paste
Cream, adds honey, and mixing boils 10-30min, obtains medicinal extract；The mass ratio of paste cream and honey is (3.5-4.5) ︰ (5.5-
6.5)；
2）The production of patch：Take cream medicated plaster, by step 1）Medicinal extract be placed in the seepage-proofing ring of plaster adhesive patch, flatten to get pain
It is pasted through navel.
The preparation method of deer placenta polypeptide：After the cleaning of deer placenta, at 75-85 DEG C, 20-30min is toasted, takes out, crush
At fine powder, deer placenta polypeptide is obtained.
Step 2）Middle seepage-proofing ring is rounded, internal diameter 3cm, depth 1.5-2.0mm；Medicinal extract in each seepage-proofing ring is used
Amount is 1.5-2.0g.
Application method：Start within 5-7 days before official holiday to stick dysmenorrhea navel patch, a daily patch does not stick during official holiday.
Compared with prior art, the invention has the advantages that：
Deer placenta polypeptide has the effect of warm palace, antalgic, motherwort have warm palace temperature through the effect of, safflower has promoting blood circulation to function
Effect, baked ginger have warm palace to act on, and Radix Astragali has the benefits of tonifying Qi, and Gui Zhi, the root of Dahurain angelica have the benefits of analgesic.The present invention by deer placenta polypeptide, motherwort,
Medicinal extract is made in safflower, baked ginger etc., then patch is made, and can warm up palace dredging collateral, conditioning palace cold, supplement qi and blood, be effectively improved cramp
Through caused discomfort.
Specific embodiment
Embodiment 1
Dysmenorrhea navel patch, effective component includes the raw material of following parts by weight：1.0 parts of deer placenta polypeptide, 0.08 part of motherwort, safflower
0.1 part, 0.03 part of baked ginger, 0.04 part of Radix Astragali, 0.04 part of Gui Zhi, 0.02 part of the root of Dahurain angelica.
The method for preparing dysmenorrhea navel patch, includes the following steps：
1）The production of medicinal extract：After each raw material is ground into mixed powder by corresponding proportion, it is added to the water immersion（Water submerged mixing medicine
Powder）, tanning（High fire is boiled, moderate heat, tanning 3h or so is adjusted to, until in the pasty state）, paste cream, Guan Huo are obtained, addition honey mixes
It closes, moderate heat boils 30min, obtains medicinal extract；The mass ratio of paste cream and honey is 4 ︰ 6；
2）The production of patch：Take cream medicated plaster, by step 1）Medicinal extract be placed in the seepage-proofing ring of plaster adhesive patch, flatten to get pain
It is pasted through navel；Seepage-proofing ring is rounded, internal diameter 3cm, depth 2.0mm, and the medicinal extract dosage in each seepage-proofing ring is 1.5g.Every patch
The weight of dysmenorrhea navel patch is about 3g.
The preparation method of deer placenta polypeptide：It after deer placenta wash with distilled water 3 times, is placed in baking box, at 80 DEG C, dries
Roasting 30min, takes out, is ground into fine powder（It is crossed 2 times with 80 mesh sieve, then with 120 mesh sieve, 200 mesh sieve, each mistake of 260 mesh sieve
3 times）, obtain deer placenta polypeptide.
Embodiment 2
Dysmenorrhea navel patch, effective component includes the raw material of following parts by weight：0.5 part of deer placenta polypeptide, 0.1 part of motherwort, safflower
0.05 part, 0.02 part of baked ginger, 0.05 part of Radix Astragali, 0.02 part of Gui Zhi, 0.05 part of the root of Dahurain angelica.
The method for preparing dysmenorrhea navel patch, includes the following steps：
1）The production of medicinal extract：After each raw material is ground into mixed powder by corresponding proportion, it is added to the water immersion（Water submerged mixing medicine
Powder）, tanning（High fire is boiled, moderate heat, tanning 3h or so is adjusted to, until in the pasty state）, paste cream, Guan Huo are obtained, addition honey mixes
It closes, moderate heat boils 20min, obtains medicinal extract；The mass ratio of paste cream and honey is 4.5 ︰ 5.5；
2）The production of patch：Take cream medicated plaster, by step 1）Medicinal extract be placed in the seepage-proofing ring of plaster adhesive patch, flatten to get pain
It is pasted through navel；Seepage-proofing ring is rounded, internal diameter 3cm, depth 1.5mm；Medicinal extract dosage in each seepage-proofing ring is 2.0g.
The weight of every patch dysmenorrhea navel patch is about 3g.
The preparation method of deer placenta polypeptide：It after deer placenta wash with distilled water 2 times, is placed in baking box, at 85 DEG C, dries
Roasting 20min, takes out, is ground into fine powder（It is crossed 2 times with 80 mesh sieve, then with 120 mesh sieve, 200 mesh sieve, each mistake of 260 mesh sieve
3 times）, obtain deer placenta polypeptide.
Embodiment 3
Dysmenorrhea navel patch, effective component includes the raw material of following parts by weight：1.5 parts of deer placenta polypeptide, 0.09 part of motherwort, safflower
0.08 part, 0.05 part of baked ginger, 0.02 part of Radix Astragali, 0.05 part of Gui Zhi, 0.04 part of the root of Dahurain angelica.
Preparation method is referring to embodiment 1.
Embodiment 4
Dysmenorrhea navel patch, effective component includes the raw material of following parts by weight：1.2 parts of deer placenta polypeptide, 0.08 part of motherwort, safflower
0.1 part, 0.04 part of baked ginger, 0.04 part of Radix Astragali, 0.04 part of Gui Zhi, 0.05 part of the root of Dahurain angelica.
Preparation method is referring to embodiment 2.
5 effect case of embodiment
Case 1
Liu XX, female 19 years old, take office in the 3rd kindergarten of Zhengzhou City Jinshui District.
It is using the symptom that dysmenorrhea navel pastes early period：Monthly want the previous day in the period, lower abdominal pain unbearably so that shadow
It rings and arrives teaching.
Treatment method：In March, 2018, the first seven day of menstruation begin to use dysmenorrhea navel to paste, and a daily patch uses the 6 later examples of patch
Vacation, feeling of pain is substantially reduced, can participate in normal teaching.
Case 2
King XX, female 20 years old, take office in the 3rd kindergarten of Zhengzhou City Jinshui District.
It is using the symptom that dysmenorrhea navel pastes early period：Monthly want it is in the period a few days ago, hence it is evident that feel the aching and tired inability of lower limb.
Treatment method：2 months 2018, first five day of menstruation started to lose money in a business the dysmenorrhea navel patch of invention, a daily patch, second month
Come before official holiday in 3-5 days substantially without aching and tired powerless feeling, according to said method, after treatment 3 months, 3 months, official holiday is completely just
Often, life is worked normally.
Case 3
Lee XX, female 18 years old, take office in Zhengzhou City Jinshui District Rhein sunlight kindergarten.
It is using the symptom that dysmenorrhea navel pastes early period：Monthly want it is in the period a few days ago, hence it is evident that feel in great pain, monthly
To alleviate official holiday bring pain, this symptoms last 2-3 to take pain piece.
Treatment method：Dysmenorrhea navel of the invention is sticked from December, 2017 to paste 7 days, carrys out pain before official holiday in January, 2018
Remission is many.2 months 2018, the symptom of official holiday pain there is no.Dysmenorrhea navel patch is sticked in March, 2018 after 7 days,
Official holiday absolutely not what symptom carried out, from however come.
Claims (5)
1. a kind of dysmenorrhea navel patch, which is characterized in that its effective component includes the raw material of following parts by weight：Deer placenta polypeptide 0.5-1.5
Part, 0.08-0.1 parts of motherwort, 0.05-0.1 parts of safflower, 0.02-0.05 parts of baked ginger, 0.02-0.05 parts of Radix Astragali, Gui Zhi 0.02-
0.05 part, 0.02-0.05 parts of the root of Dahurain angelica.
2. dysmenorrhea navel patch as described in claim 1, which is characterized in that its effective component includes the raw material of following parts by weight：Deer
1.0 parts of placenta peptide, 0.08 part of motherwort, 0.1 part of safflower, 0.03 part of baked ginger, 0.04 part of Radix Astragali, 0.04 part of Gui Zhi, the root of Dahurain angelica 0.02
Part.
3. the method for preparing dysmenorrhea navel patch as described in claim 1, which is characterized in that include the following steps：
1）The production of medicinal extract：After each raw material is ground into mixed powder by corresponding proportion, it is added to the water immersion, boils, obtain paste
Cream, adds honey, and mixing boils 10-30min, obtains medicinal extract；The mass ratio of paste cream and honey is (3.5-4.5) ︰ (5.5-
6.5)；
2）The production of patch：Take cream medicated plaster, by step 1）Medicinal extract be placed in the seepage-proofing ring of plaster adhesive patch, flatten to get pain
It is pasted through navel.
4. the method for preparation dysmenorrhea navel patch as claimed in claim 3, which is characterized in that the preparation method of deer placenta polypeptide：By deer
After placenta cleaning, at 75-85 DEG C, 20-30min is toasted, takes out, be ground into fine powder, obtain deer placenta polypeptide.
5. the method for preparation dysmenorrhea navel patch as claimed in claim 3, which is characterized in that step 2）Middle seepage-proofing ring is rounded,
Internal diameter is 3cm, depth 1.5-2.0mm；Medicinal extract dosage in each seepage-proofing ring is 1.5-2.0g.
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| CN201810817009.XA CN108853449A (en) | 2018-07-24 | 2018-07-24 | A kind of dysmenorrhea navel patch and preparation method thereof |
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| CN201810817009.XA CN108853449A (en) | 2018-07-24 | 2018-07-24 | A kind of dysmenorrhea navel patch and preparation method thereof |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1234237A (en) * | 1998-05-06 | 1999-11-10 | 李锐 | Chinese medicine preparation for radically curing dyamenorrhea and its preparation method and using method |
| CN105326942A (en) * | 2015-12-01 | 2016-02-17 | 骆志明 | Detoxifying and beautifying foot bath formula |
| CN105597067A (en) * | 2016-02-04 | 2016-05-25 | 夏书升 | Pure traditional Chinese medicinal ointment for thermal therapy and external application |
| CN107753553A (en) * | 2017-11-07 | 2018-03-06 | 沈阳兴润药物研究所 | Acupoint application treatment pastes |
-
2018
- 2018-07-24 CN CN201810817009.XA patent/CN108853449A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1234237A (en) * | 1998-05-06 | 1999-11-10 | 李锐 | Chinese medicine preparation for radically curing dyamenorrhea and its preparation method and using method |
| CN105326942A (en) * | 2015-12-01 | 2016-02-17 | 骆志明 | Detoxifying and beautifying foot bath formula |
| CN105597067A (en) * | 2016-02-04 | 2016-05-25 | 夏书升 | Pure traditional Chinese medicinal ointment for thermal therapy and external application |
| CN107753553A (en) * | 2017-11-07 | 2018-03-06 | 沈阳兴润药物研究所 | Acupoint application treatment pastes |
Non-Patent Citations (1)
| Title |
|---|
| 孔秀玲等: "神阙穴隔物灸治疗原发性痛经", 《山东中医杂志》 * |
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Application publication date: 20181123 |