CN108850507A - Lactobacillus bulgaricus feed addictive - Google Patents
Lactobacillus bulgaricus feed addictive Download PDFInfo
- Publication number
- CN108850507A CN108850507A CN201810512030.9A CN201810512030A CN108850507A CN 108850507 A CN108850507 A CN 108850507A CN 201810512030 A CN201810512030 A CN 201810512030A CN 108850507 A CN108850507 A CN 108850507A
- Authority
- CN
- China
- Prior art keywords
- freeze
- dried powder
- powder
- sea
- cactus
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 235000013960 Lactobacillus bulgaricus Nutrition 0.000 title claims abstract description 85
- 229940004208 lactobacillus bulgaricus Drugs 0.000 title claims abstract description 85
- 241000186672 Lactobacillus delbrueckii subsp. bulgaricus Species 0.000 title 1
- 239000000843 powder Substances 0.000 claims abstract description 337
- 102000002322 Egg Proteins Human genes 0.000 claims abstract description 128
- 108010000912 Egg Proteins Proteins 0.000 claims abstract description 128
- 210000003278 egg shell Anatomy 0.000 claims abstract description 124
- 244000199885 Lactobacillus bulgaricus Species 0.000 claims abstract description 84
- 241000219357 Cactaceae Species 0.000 claims abstract description 81
- 235000001466 Ribes nigrum Nutrition 0.000 claims abstract description 79
- 235000003145 Hippophae rhamnoides Nutrition 0.000 claims abstract description 78
- 235000016954 Ribes hudsonianum Nutrition 0.000 claims abstract description 78
- 235000000340 Solanum pseudocapsicum Nutrition 0.000 claims abstract description 77
- 240000004482 Withania somnifera Species 0.000 claims abstract description 77
- 235000001978 Withania somnifera Nutrition 0.000 claims abstract description 77
- 240000001890 Ribes hudsonianum Species 0.000 claims abstract description 73
- 240000002547 Rosa roxburghii Species 0.000 claims abstract description 73
- 235000000640 Rosa roxburghii Nutrition 0.000 claims abstract description 73
- 235000012054 meals Nutrition 0.000 claims abstract description 66
- 239000002131 composite material Substances 0.000 claims abstract description 42
- 238000004806 packaging method and process Methods 0.000 claims abstract description 42
- 241000894006 Bacteria Species 0.000 claims abstract description 31
- 239000000463 material Substances 0.000 claims description 58
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims description 50
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims description 35
- 238000000034 method Methods 0.000 claims description 30
- 239000002994 raw material Substances 0.000 claims description 28
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims description 27
- 238000004108 freeze drying Methods 0.000 claims description 27
- 238000002156 mixing Methods 0.000 claims description 27
- 230000004913 activation Effects 0.000 claims description 26
- 238000001994 activation Methods 0.000 claims description 26
- 235000013399 edible fruits Nutrition 0.000 claims description 23
- 241000229143 Hippophae Species 0.000 claims description 21
- 239000011780 sodium chloride Substances 0.000 claims description 17
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 claims description 16
- 230000008569 process Effects 0.000 claims description 16
- 241000193830 Bacillus <bacterium> Species 0.000 claims description 14
- 238000001035 drying Methods 0.000 claims description 14
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 claims description 12
- VYPSYNLAJGMNEJ-UHFFFAOYSA-N Silicium dioxide Chemical compound O=[Si]=O VYPSYNLAJGMNEJ-UHFFFAOYSA-N 0.000 claims description 12
- 238000007710 freezing Methods 0.000 claims description 12
- 230000008014 freezing Effects 0.000 claims description 12
- -1 polypropylene Polymers 0.000 claims description 12
- 239000000741 silica gel Substances 0.000 claims description 12
- 229910002027 silica gel Inorganic materials 0.000 claims description 12
- 239000004743 Polypropylene Substances 0.000 claims description 11
- 239000005030 aluminium foil Substances 0.000 claims description 11
- 239000004033 plastic Substances 0.000 claims description 11
- 229920003023 plastic Polymers 0.000 claims description 11
- 229920001155 polypropylene Polymers 0.000 claims description 11
- 238000012216 screening Methods 0.000 claims description 11
- 150000003839 salts Chemical class 0.000 claims description 10
- 238000000227 grinding Methods 0.000 claims description 9
- 238000010000 carbonizing Methods 0.000 claims description 8
- 238000004140 cleaning Methods 0.000 claims description 7
- 238000005406 washing Methods 0.000 claims description 7
- 239000012190 activator Substances 0.000 claims description 6
- 239000001569 carbon dioxide Substances 0.000 claims description 6
- 229910002092 carbon dioxide Inorganic materials 0.000 claims description 6
- 230000008859 change Effects 0.000 claims description 6
- 239000012535 impurity Substances 0.000 claims description 6
- 238000007598 dipping method Methods 0.000 claims description 5
- 230000008520 organization Effects 0.000 claims description 5
- 241000272814 Anser sp. Species 0.000 claims description 4
- 241000286209 Phasianidae Species 0.000 claims description 4
- 239000003610 charcoal Substances 0.000 claims description 4
- 239000007921 spray Substances 0.000 claims description 4
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 claims description 3
- 210000004681 ovum Anatomy 0.000 claims description 3
- 239000011734 sodium Substances 0.000 claims description 3
- 229910052708 sodium Inorganic materials 0.000 claims description 3
- 241000272522 Anas Species 0.000 claims description 2
- 241001052560 Thallis Species 0.000 claims description 2
- 235000013336 milk Nutrition 0.000 claims description 2
- 239000008267 milk Substances 0.000 claims description 2
- 210000004080 milk Anatomy 0.000 claims description 2
- 238000012856 packing Methods 0.000 claims description 2
- ZAMOUSCENKQFHK-UHFFFAOYSA-N Chlorine atom Chemical compound [Cl] ZAMOUSCENKQFHK-UHFFFAOYSA-N 0.000 claims 2
- 239000000460 chlorine Substances 0.000 claims 2
- 229910052801 chlorine Inorganic materials 0.000 claims 2
- 229940098458 powder spray Drugs 0.000 claims 2
- 238000000746 purification Methods 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
- 240000000950 Hippophae rhamnoides Species 0.000 abstract description 58
- 241001465754 Metazoa Species 0.000 abstract description 28
- 239000000654 additive Substances 0.000 abstract description 12
- 230000000996 additive effect Effects 0.000 abstract description 12
- 230000001737 promoting effect Effects 0.000 abstract description 8
- 230000000050 nutritive effect Effects 0.000 abstract description 6
- 230000008901 benefit Effects 0.000 abstract description 5
- 239000011159 matrix material Substances 0.000 abstract description 3
- 238000009360 aquaculture Methods 0.000 abstract description 2
- 244000144974 aquaculture Species 0.000 abstract description 2
- 201000010099 disease Diseases 0.000 abstract description 2
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract description 2
- 230000004060 metabolic process Effects 0.000 abstract description 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 description 38
- CIWBSHSKHKDKBQ-JLAZNSOCSA-N Ascorbic acid Chemical compound OC[C@H](O)[C@H]1OC(=O)C(O)=C1O CIWBSHSKHKDKBQ-JLAZNSOCSA-N 0.000 description 20
- 239000004310 lactic acid Substances 0.000 description 19
- 235000014655 lactic acid Nutrition 0.000 description 19
- 241000186660 Lactobacillus Species 0.000 description 14
- 229940039696 lactobacillus Drugs 0.000 description 14
- 239000000203 mixture Substances 0.000 description 14
- 238000004519 manufacturing process Methods 0.000 description 12
- 239000000126 substance Substances 0.000 description 12
- 239000002274 desiccant Substances 0.000 description 11
- 230000000694 effects Effects 0.000 description 11
- 229960001866 silicon dioxide Drugs 0.000 description 11
- ZZZCUOFIHGPKAK-UHFFFAOYSA-N D-erythro-ascorbic acid Natural products OCC1OC(=O)C(O)=C1O ZZZCUOFIHGPKAK-UHFFFAOYSA-N 0.000 description 10
- 229930003268 Vitamin C Natural products 0.000 description 10
- 238000002360 preparation method Methods 0.000 description 10
- 235000019154 vitamin C Nutrition 0.000 description 10
- 239000011718 vitamin C Substances 0.000 description 10
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 8
- 239000011575 calcium Substances 0.000 description 8
- 229910052791 calcium Inorganic materials 0.000 description 8
- 235000013601 eggs Nutrition 0.000 description 8
- 235000016709 nutrition Nutrition 0.000 description 8
- 235000013339 cereals Nutrition 0.000 description 7
- 230000006870 function Effects 0.000 description 7
- 241001312569 Ribes nigrum Species 0.000 description 6
- 235000013305 food Nutrition 0.000 description 6
- 239000004615 ingredient Substances 0.000 description 6
- 241000781608 Scolopia zeyheri Species 0.000 description 5
- 239000002253 acid Substances 0.000 description 5
- 150000001413 amino acids Chemical class 0.000 description 5
- 229930014669 anthocyanidin Natural products 0.000 description 5
- 150000001452 anthocyanidin derivatives Chemical class 0.000 description 5
- 235000008758 anthocyanidins Nutrition 0.000 description 5
- 235000021028 berry Nutrition 0.000 description 5
- 235000015165 citric acid Nutrition 0.000 description 5
- 230000029087 digestion Effects 0.000 description 5
- 239000000945 filler Substances 0.000 description 5
- 230000000968 intestinal effect Effects 0.000 description 5
- 230000035764 nutrition Effects 0.000 description 5
- 244000144977 poultry Species 0.000 description 5
- 238000003756 stirring Methods 0.000 description 5
- 210000002784 stomach Anatomy 0.000 description 5
- 229930003231 vitamin Natural products 0.000 description 5
- 235000013343 vitamin Nutrition 0.000 description 5
- 239000011782 vitamin Substances 0.000 description 5
- 229940088594 vitamin Drugs 0.000 description 5
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical compound [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 4
- 206010012735 Diarrhoea Diseases 0.000 description 4
- 244000064622 Physalis edulis Species 0.000 description 4
- GLUUGHFHXGJENI-UHFFFAOYSA-N Piperazine Chemical compound C1CNCCN1 GLUUGHFHXGJENI-UHFFFAOYSA-N 0.000 description 4
- 230000002378 acidificating effect Effects 0.000 description 4
- 238000005054 agglomeration Methods 0.000 description 4
- 230000002776 aggregation Effects 0.000 description 4
- 239000003674 animal food additive Substances 0.000 description 4
- 238000003763 carbonization Methods 0.000 description 4
- 239000003814 drug Substances 0.000 description 4
- 201000006549 dyspepsia Diseases 0.000 description 4
- 239000007789 gas Substances 0.000 description 4
- 229910052500 inorganic mineral Inorganic materials 0.000 description 4
- 235000015110 jellies Nutrition 0.000 description 4
- 239000008274 jelly Substances 0.000 description 4
- 230000000813 microbial effect Effects 0.000 description 4
- 235000010755 mineral Nutrition 0.000 description 4
- 239000011707 mineral Substances 0.000 description 4
- 150000003722 vitamin derivatives Chemical class 0.000 description 4
- OAICVXFJPJFONN-UHFFFAOYSA-N Phosphorus Chemical compound [P] OAICVXFJPJFONN-UHFFFAOYSA-N 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 235000014633 carbohydrates Nutrition 0.000 description 3
- 150000001720 carbohydrates Chemical class 0.000 description 3
- 239000002552 dosage form Substances 0.000 description 3
- 208000001848 dysentery Diseases 0.000 description 3
- 238000000855 fermentation Methods 0.000 description 3
- 230000004151 fermentation Effects 0.000 description 3
- 239000000796 flavoring agent Substances 0.000 description 3
- 235000019634 flavors Nutrition 0.000 description 3
- 235000021022 fresh fruits Nutrition 0.000 description 3
- 239000003292 glue Substances 0.000 description 3
- 238000007689 inspection Methods 0.000 description 3
- 239000007788 liquid Substances 0.000 description 3
- 150000007524 organic acids Chemical class 0.000 description 3
- 244000052769 pathogen Species 0.000 description 3
- 239000011574 phosphorus Substances 0.000 description 3
- 229910052698 phosphorus Inorganic materials 0.000 description 3
- 239000012266 salt solution Substances 0.000 description 3
- 238000007790 scraping Methods 0.000 description 3
- 210000000813 small intestine Anatomy 0.000 description 3
- 238000003860 storage Methods 0.000 description 3
- 235000000346 sugar Nutrition 0.000 description 3
- 230000004083 survival effect Effects 0.000 description 3
- 239000011701 zinc Substances 0.000 description 3
- GHOKWGTUZJEAQD-ZETCQYMHSA-N (D)-(+)-Pantothenic acid Chemical compound OCC(C)(C)[C@@H](O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-ZETCQYMHSA-N 0.000 description 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 description 2
- 244000298715 Actinidia chinensis Species 0.000 description 2
- 235000009434 Actinidia chinensis Nutrition 0.000 description 2
- 235000009436 Actinidia deliciosa Nutrition 0.000 description 2
- QGZKDVFQNNGYKY-UHFFFAOYSA-N Ammonia Chemical compound N QGZKDVFQNNGYKY-UHFFFAOYSA-N 0.000 description 2
- 241000272525 Anas platyrhynchos Species 0.000 description 2
- 108010062877 Bacteriocins Proteins 0.000 description 2
- 241000207199 Citrus Species 0.000 description 2
- 206010011224 Cough Diseases 0.000 description 2
- 244000000626 Daucus carota Species 0.000 description 2
- 235000002767 Daucus carota Nutrition 0.000 description 2
- 241000196324 Embryophyta Species 0.000 description 2
- 241000194032 Enterococcus faecalis Species 0.000 description 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 description 2
- 241000287828 Gallus gallus Species 0.000 description 2
- 235000007688 Lycopersicon esculentum Nutrition 0.000 description 2
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 2
- 208000002193 Pain Diseases 0.000 description 2
- 241001106044 Physalis Species 0.000 description 2
- 235000009230 Physalis pubescens Nutrition 0.000 description 2
- 235000002491 Physalis viscosa Nutrition 0.000 description 2
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 2
- REFJWTPEDVJJIY-UHFFFAOYSA-N Quercetin Chemical compound C=1C(O)=CC(O)=C(C(C=2O)=O)C=1OC=2C1=CC=C(O)C(O)=C1 REFJWTPEDVJJIY-UHFFFAOYSA-N 0.000 description 2
- 235000016998 Ribes burejense Nutrition 0.000 description 2
- 241000735566 Ribes burejense Species 0.000 description 2
- 240000003768 Solanum lycopersicum Species 0.000 description 2
- 240000008042 Zea mays Species 0.000 description 2
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 239000003463 adsorbent Substances 0.000 description 2
- 238000007605 air drying Methods 0.000 description 2
- OENHQHLEOONYIE-UKMVMLAPSA-N all-trans beta-carotene Natural products CC=1CCCC(C)(C)C=1/C=C/C(/C)=C/C=C/C(/C)=C/C=C/C=C(C)C=CC=C(C)C=CC1=C(C)CCCC1(C)C OENHQHLEOONYIE-UKMVMLAPSA-N 0.000 description 2
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 239000007864 aqueous solution Substances 0.000 description 2
- 239000012752 auxiliary agent Substances 0.000 description 2
- 230000009286 beneficial effect Effects 0.000 description 2
- 239000011648 beta-carotene Substances 0.000 description 2
- 235000013734 beta-carotene Nutrition 0.000 description 2
- TUPZEYHYWIEDIH-WAIFQNFQSA-N beta-carotene Natural products CC(=C/C=C/C=C(C)/C=C/C=C(C)/C=C/C1=C(C)CCCC1(C)C)C=CC=C(/C)C=CC2=CCCCC2(C)C TUPZEYHYWIEDIH-WAIFQNFQSA-N 0.000 description 2
- 229960002747 betacarotene Drugs 0.000 description 2
- 244000144987 brood Species 0.000 description 2
- 229910000019 calcium carbonate Inorganic materials 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 229910052799 carbon Inorganic materials 0.000 description 2
- 235000020971 citrus fruits Nutrition 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 238000011161 development Methods 0.000 description 2
- 230000001079 digestive effect Effects 0.000 description 2
- 229940079593 drug Drugs 0.000 description 2
- 229930003944 flavone Natural products 0.000 description 2
- 235000011949 flavones Nutrition 0.000 description 2
- 235000013312 flour Nutrition 0.000 description 2
- OVBPIULPVIDEAO-LBPRGKRZSA-N folic acid Chemical compound C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)N[C@@H](CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-LBPRGKRZSA-N 0.000 description 2
- 238000009472 formulation Methods 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- XTLWNMXYCHABQH-UHFFFAOYSA-N germanicol Natural products CC1(C)CCC2(C)CCC3(C)C(CCC4(C)C5(C)CCC(O)C(C)(C)C5CCC34C)C2=C1 XTLWNMXYCHABQH-UHFFFAOYSA-N 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 210000002429 large intestine Anatomy 0.000 description 2
- 239000010410 layer Substances 0.000 description 2
- 244000144972 livestock Species 0.000 description 2
- 239000011777 magnesium Substances 0.000 description 2
- 229910052749 magnesium Inorganic materials 0.000 description 2
- 239000001630 malic acid Substances 0.000 description 2
- 235000011090 malic acid Nutrition 0.000 description 2
- 235000013372 meat Nutrition 0.000 description 2
- 230000007246 mechanism Effects 0.000 description 2
- 239000002366 mineral element Substances 0.000 description 2
- 230000036407 pain Effects 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000001717 pathogenic effect Effects 0.000 description 2
- 231100000614 poison Toxicity 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- 239000011591 potassium Substances 0.000 description 2
- 229910052700 potassium Inorganic materials 0.000 description 2
- 238000012913 prioritisation Methods 0.000 description 2
- 239000006041 probiotic Substances 0.000 description 2
- 230000000529 probiotic effect Effects 0.000 description 2
- 235000018291 probiotics Nutrition 0.000 description 2
- 238000012545 processing Methods 0.000 description 2
- 235000018102 proteins Nutrition 0.000 description 2
- 102000004169 proteins and genes Human genes 0.000 description 2
- 108090000623 proteins and genes Proteins 0.000 description 2
- 239000013558 reference substance Substances 0.000 description 2
- 239000000243 solution Substances 0.000 description 2
- 235000013599 spices Nutrition 0.000 description 2
- ZYOCVAPRXVCQQR-UHFFFAOYSA-N taraxasterone Natural products CC12CCC(=O)C(C)(C)C1CCC1(C)C2CCC2C3C(C)C(=C)CCC3(C)CCC21C ZYOCVAPRXVCQQR-UHFFFAOYSA-N 0.000 description 2
- GGGUGZHBAOMSFJ-GADYQYKKSA-N taraxerol Chemical compound CC([C@@H]1CC2)(C)[C@@H](O)CC[C@]1(C)[C@@H]1[C@]2(C)C2=CC[C@@]3(C)CCC(C)(C)C[C@H]3[C@]2(C)CC1 GGGUGZHBAOMSFJ-GADYQYKKSA-N 0.000 description 2
- HYTFUKZLSYXRDX-UHFFFAOYSA-N taraxerol Natural products CC1CCCC2C3(C)CCC4(C)C5CC(C)(C)CCC5(C)C=CC4(C)C3C(O)CC12C HYTFUKZLSYXRDX-UHFFFAOYSA-N 0.000 description 2
- DBCAVZSSFGIHQZ-YLAYQGCQSA-N taraxerone Chemical compound CC([C@@H]1CC2)(C)C(=O)CC[C@]1(C)[C@@H]1[C@]2(C)C2=CC[C@@]3(C)CCC(C)(C)C[C@H]3[C@]2(C)CC1 DBCAVZSSFGIHQZ-YLAYQGCQSA-N 0.000 description 2
- FXOCQCYCKZXBIJ-UHFFFAOYSA-N taraxerone Natural products CC1C=C2C(C)(CCC3C4(C)CCC(=O)C(C)(C)C4CCC23C)C5CC(C)(C)CCC15 FXOCQCYCKZXBIJ-UHFFFAOYSA-N 0.000 description 2
- 239000003053 toxin Substances 0.000 description 2
- 231100000765 toxin Toxicity 0.000 description 2
- 239000011573 trace mineral Substances 0.000 description 2
- 235000013619 trace mineral Nutrition 0.000 description 2
- 235000015099 wheat brans Nutrition 0.000 description 2
- 229910052725 zinc Inorganic materials 0.000 description 2
- OENHQHLEOONYIE-JLTXGRSLSA-N β-Carotene Chemical compound CC=1CCCC(C)(C)C=1\C=C\C(\C)=C\C=C\C(\C)=C\C=C\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C OENHQHLEOONYIE-JLTXGRSLSA-N 0.000 description 2
- PFTAWBLQPZVEMU-DZGCQCFKSA-N (+)-catechin Chemical compound C1([C@H]2OC3=CC(O)=CC(O)=C3C[C@@H]2O)=CC=C(O)C(O)=C1 PFTAWBLQPZVEMU-DZGCQCFKSA-N 0.000 description 1
- XCDQFROEGGNAER-VYFOYESCSA-N (3r,4r,4as,6as,6as,6br,8ar,12ar,14as,14bs)-4,4a,6a,6b,8a,11,11,14a-octamethyl-1,2,3,4,5,6,6a,7,8,9,10,12,12a,13,14,14b-hexadecahydropicen-3-ol Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3CC[C@@H](O)[C@@H]1C XCDQFROEGGNAER-VYFOYESCSA-N 0.000 description 1
- QCVGEOXPDFCNHA-UHFFFAOYSA-N 5,5-dimethyl-2,4-dioxo-1,3-oxazolidine-3-carboxamide Chemical compound CC1(C)OC(=O)N(C(N)=O)C1=O QCVGEOXPDFCNHA-UHFFFAOYSA-N 0.000 description 1
- 206010000060 Abdominal distension Diseases 0.000 description 1
- 235000017060 Arachis glabrata Nutrition 0.000 description 1
- 244000105624 Arachis hypogaea Species 0.000 description 1
- 235000010777 Arachis hypogaea Nutrition 0.000 description 1
- 235000018262 Arachis monticola Nutrition 0.000 description 1
- 208000006770 Ascorbic Acid Deficiency Diseases 0.000 description 1
- 102000040350 B family Human genes 0.000 description 1
- 108091072128 B family Proteins 0.000 description 1
- 102100026189 Beta-galactosidase Human genes 0.000 description 1
- 241001164374 Calyx Species 0.000 description 1
- 244000025254 Cannabis sativa Species 0.000 description 1
- OKTJSMMVPCPJKN-UHFFFAOYSA-N Carbon Chemical compound [C] OKTJSMMVPCPJKN-UHFFFAOYSA-N 0.000 description 1
- GHOKWGTUZJEAQD-UHFFFAOYSA-N Chick antidermatitis factor Natural products OCC(C)(C)C(O)C(=O)NCCC(O)=O GHOKWGTUZJEAQD-UHFFFAOYSA-N 0.000 description 1
- 241001112696 Clostridia Species 0.000 description 1
- 241000193403 Clostridium Species 0.000 description 1
- 235000009917 Crataegus X brevipes Nutrition 0.000 description 1
- 235000013204 Crataegus X haemacarpa Nutrition 0.000 description 1
- 235000009685 Crataegus X maligna Nutrition 0.000 description 1
- 235000009444 Crataegus X rubrocarnea Nutrition 0.000 description 1
- 235000009486 Crataegus bullatus Nutrition 0.000 description 1
- 235000017181 Crataegus chrysocarpa Nutrition 0.000 description 1
- 235000009682 Crataegus limnophila Nutrition 0.000 description 1
- 240000000171 Crataegus monogyna Species 0.000 description 1
- 235000004423 Crataegus monogyna Nutrition 0.000 description 1
- 235000002313 Crataegus paludosa Nutrition 0.000 description 1
- 235000009840 Crataegus x incaedua Nutrition 0.000 description 1
- 235000001427 Cylindropuntia imbricata Nutrition 0.000 description 1
- 240000005729 Cylindropuntia imbricata Species 0.000 description 1
- KVSNMTUIMXZPLU-UHFFFAOYSA-N D:A-friedo-oleanane Natural products CC12CCC3(C)C4CC(C)(C)CCC4(C)CCC3(C)C2CCC2(C)C1CCCC2C KVSNMTUIMXZPLU-UHFFFAOYSA-N 0.000 description 1
- 208000035240 Disease Resistance Diseases 0.000 description 1
- 101100276976 Drosophila melanogaster Drak gene Proteins 0.000 description 1
- 208000004232 Enteritis Diseases 0.000 description 1
- 241000305071 Enterobacterales Species 0.000 description 1
- 101710146739 Enterotoxin Proteins 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 201000000297 Erysipelas Diseases 0.000 description 1
- 241000588724 Escherichia coli Species 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- FRRPUSYZJQBRAG-UHFFFAOYSA-N Friedelan-3alpha-ol Natural products CC1C(O)CCC2C3CCC4(C)C5CC(C)(C)CCC5(C)CCC4(C)C3CCC12C FRRPUSYZJQBRAG-UHFFFAOYSA-N 0.000 description 1
- JUUHNUPNMCGYDT-UHFFFAOYSA-N Friedelin Natural products CC1CC2C(C)(CCC3(C)C4CC(C)(C)CCC4(C)CCC23C)C5CCC(=O)C(C)C15 JUUHNUPNMCGYDT-UHFFFAOYSA-N 0.000 description 1
- 206010017553 Furuncle Diseases 0.000 description 1
- WQZGKKKJIJFFOK-GASJEMHNSA-N Glucose Chemical compound OC[C@H]1OC(O)[C@H](O)[C@@H](O)[C@@H]1O WQZGKKKJIJFFOK-GASJEMHNSA-N 0.000 description 1
- SQUHHTBVTRBESD-UHFFFAOYSA-N Hexa-Ac-myo-Inositol Natural products CC(=O)OC1C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C(OC(C)=O)C1OC(C)=O SQUHHTBVTRBESD-UHFFFAOYSA-N 0.000 description 1
- 235000003935 Hippophae Nutrition 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 206010020772 Hypertension Diseases 0.000 description 1
- 206010020880 Hypertrophy Diseases 0.000 description 1
- 206010023126 Jaundice Diseases 0.000 description 1
- 108010059881 Lactase Proteins 0.000 description 1
- 240000001046 Lactobacillus acidophilus Species 0.000 description 1
- 235000013956 Lactobacillus acidophilus Nutrition 0.000 description 1
- 241000186673 Lactobacillus delbrueckii Species 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- 235000005079 Malus baccata Nutrition 0.000 description 1
- 244000134336 Malus baccata Species 0.000 description 1
- 244000132436 Myrica rubra Species 0.000 description 1
- OVBPIULPVIDEAO-UHFFFAOYSA-N N-Pteroyl-L-glutaminsaeure Natural products C=1N=C2NC(N)=NC(=O)C2=NC=1CNC1=CC=C(C(=O)NC(CCC(O)=O)C(O)=O)C=C1 OVBPIULPVIDEAO-UHFFFAOYSA-N 0.000 description 1
- 240000002853 Nelumbo nucifera Species 0.000 description 1
- 235000006508 Nelumbo nucifera Nutrition 0.000 description 1
- 235000006510 Nelumbo pentapetala Nutrition 0.000 description 1
- PVNIIMVLHYAWGP-UHFFFAOYSA-N Niacin Chemical compound OC(=O)C1=CC=CN=C1 PVNIIMVLHYAWGP-UHFFFAOYSA-N 0.000 description 1
- 240000001439 Opuntia Species 0.000 description 1
- 241001378084 Opuntia stricta Species 0.000 description 1
- 240000007594 Oryza sativa Species 0.000 description 1
- 235000007164 Oryza sativa Nutrition 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
- 235000001982 Physalis edulis Nutrition 0.000 description 1
- 208000004880 Polyuria Diseases 0.000 description 1
- 241000589516 Pseudomonas Species 0.000 description 1
- 241000220324 Pyrus Species 0.000 description 1
- ZVOLCUVKHLEPEV-UHFFFAOYSA-N Quercetagetin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=C(O)C(O)=C(O)C=C2O1 ZVOLCUVKHLEPEV-UHFFFAOYSA-N 0.000 description 1
- HWTZYBCRDDUBJY-UHFFFAOYSA-N Rhynchosin Natural products C1=C(O)C(O)=CC=C1C1=C(O)C(=O)C2=CC(O)=C(O)C=C2O1 HWTZYBCRDDUBJY-UHFFFAOYSA-N 0.000 description 1
- 241000220483 Ribes Species 0.000 description 1
- 235000001537 Ribes X gardonianum Nutrition 0.000 description 1
- 235000001535 Ribes X utile Nutrition 0.000 description 1
- 235000016919 Ribes petraeum Nutrition 0.000 description 1
- 244000281247 Ribes rubrum Species 0.000 description 1
- 235000002355 Ribes spicatum Nutrition 0.000 description 1
- 235000011449 Rosa Nutrition 0.000 description 1
- 235000004789 Rosa xanthina Nutrition 0.000 description 1
- 241000220222 Rosaceae Species 0.000 description 1
- 241000235342 Saccharomycetes Species 0.000 description 1
- 241000607142 Salmonella Species 0.000 description 1
- 229920002472 Starch Polymers 0.000 description 1
- 241000194017 Streptococcus Species 0.000 description 1
- 244000057717 Streptococcus lactis Species 0.000 description 1
- 235000014897 Streptococcus lactis Nutrition 0.000 description 1
- OUUQCZGPVNCOIJ-UHFFFAOYSA-M Superoxide Chemical class [O-][O] OUUQCZGPVNCOIJ-UHFFFAOYSA-M 0.000 description 1
- 102000019197 Superoxide Dismutase Human genes 0.000 description 1
- 108010012715 Superoxide dismutase Proteins 0.000 description 1
- GAMYVSCDDLXAQW-AOIWZFSPSA-N Thermopsosid Natural products O(C)c1c(O)ccc(C=2Oc3c(c(O)cc(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](CO)O4)c3)C(=O)C=2)c1 GAMYVSCDDLXAQW-AOIWZFSPSA-N 0.000 description 1
- 235000021307 Triticum Nutrition 0.000 description 1
- 244000098338 Triticum aestivum Species 0.000 description 1
- 229930003270 Vitamin B Natural products 0.000 description 1
- 206010047623 Vitamin C deficiency Diseases 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000016383 Zea mays subsp huehuetenangensis Nutrition 0.000 description 1
- 229910021536 Zeolite Inorganic materials 0.000 description 1
- 230000002159 abnormal effect Effects 0.000 description 1
- 238000009825 accumulation Methods 0.000 description 1
- 230000001070 adhesive effect Effects 0.000 description 1
- 229910021529 ammonia Inorganic materials 0.000 description 1
- 238000003975 animal breeding Methods 0.000 description 1
- 230000001142 anti-diarrhea Effects 0.000 description 1
- 230000003064 anti-oxidating effect Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 125000003118 aryl group Chemical group 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 108010051210 beta-Fructofuranosidase Proteins 0.000 description 1
- 108010005774 beta-Galactosidase Proteins 0.000 description 1
- 239000011230 binding agent Substances 0.000 description 1
- 230000000975 bioactive effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 235000010216 calcium carbonate Nutrition 0.000 description 1
- 239000001506 calcium phosphate Substances 0.000 description 1
- 229910000389 calcium phosphate Inorganic materials 0.000 description 1
- 235000011010 calcium phosphates Nutrition 0.000 description 1
- 235000005487 catechin Nutrition 0.000 description 1
- ADRVNXBAWSRFAJ-UHFFFAOYSA-N catechin Natural products OC1Cc2cc(O)cc(O)c2OC1c3ccc(O)c(O)c3 ADRVNXBAWSRFAJ-UHFFFAOYSA-N 0.000 description 1
- 210000005056 cell body Anatomy 0.000 description 1
- 238000006243 chemical reaction Methods 0.000 description 1
- 229950001002 cianidanol Drugs 0.000 description 1
- 230000009137 competitive binding Effects 0.000 description 1
- 230000002860 competitive effect Effects 0.000 description 1
- 230000000295 complement effect Effects 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000009508 confectionery Nutrition 0.000 description 1
- 239000000470 constituent Substances 0.000 description 1
- 238000010276 construction Methods 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 238000001514 detection method Methods 0.000 description 1
- 235000014113 dietary fatty acids Nutrition 0.000 description 1
- HNPSIPDUKPIQMN-UHFFFAOYSA-N dioxosilane;oxo(oxoalumanyloxy)alumane Chemical compound O=[Si]=O.O=[Al]O[Al]=O HNPSIPDUKPIQMN-UHFFFAOYSA-N 0.000 description 1
- 238000004821 distillation Methods 0.000 description 1
- 230000035619 diuresis Effects 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 235000014103 egg white Nutrition 0.000 description 1
- 210000000969 egg white Anatomy 0.000 description 1
- 239000000147 enterotoxin Substances 0.000 description 1
- 231100000655 enterotoxin Toxicity 0.000 description 1
- 238000003912 environmental pollution Methods 0.000 description 1
- 229940088598 enzyme Drugs 0.000 description 1
- FWTBRZMBHIYQSW-UHFFFAOYSA-N epifriedelanol Natural products CC1C(O)C(O)CC2C1(C)CCC3C2(C)CCC4(C)C5CC(C)(C)CCC5(C)C(O)CC34C FWTBRZMBHIYQSW-UHFFFAOYSA-N 0.000 description 1
- 210000000981 epithelium Anatomy 0.000 description 1
- 230000007717 exclusion Effects 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 235000019197 fats Nutrition 0.000 description 1
- 239000000194 fatty acid Substances 0.000 description 1
- 229930195729 fatty acid Natural products 0.000 description 1
- 150000004665 fatty acids Chemical class 0.000 description 1
- 238000011049 filling Methods 0.000 description 1
- 206010016766 flatulence Diseases 0.000 description 1
- 150000002212 flavone derivatives Chemical class 0.000 description 1
- 150000002213 flavones Chemical class 0.000 description 1
- 239000012530 fluid Substances 0.000 description 1
- 229960000304 folic acid Drugs 0.000 description 1
- 235000019152 folic acid Nutrition 0.000 description 1
- 239000011724 folic acid Substances 0.000 description 1
- 239000003205 fragrance Substances 0.000 description 1
- OFMXGFHWLZPCFL-SVRPQWSVSA-N friedelin Chemical compound C([C@H]1[C@]2(C)CC[C@@]34C)C(C)(C)CC[C@]1(C)CC[C@]2(C)[C@H]4CC[C@@]1(C)[C@H]3CCC(=O)[C@@H]1C OFMXGFHWLZPCFL-SVRPQWSVSA-N 0.000 description 1
- MFVJCHSUSSRHRH-UHFFFAOYSA-N friedeline Natural products CC1(C)CCC2(C)CCC3C4(C)CCC5C(C)(C)C(=O)CCC5(C)C4CCC3(C)C2C1 MFVJCHSUSSRHRH-UHFFFAOYSA-N 0.000 description 1
- 235000015203 fruit juice Nutrition 0.000 description 1
- 239000001530 fumaric acid Substances 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 208000003512 furunculosis Diseases 0.000 description 1
- 239000008187 granular material Substances 0.000 description 1
- 239000001963 growth medium Substances 0.000 description 1
- 238000000703 high-speed centrifugation Methods 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 229960000367 inositol Drugs 0.000 description 1
- CDAISMWEOUEBRE-GPIVLXJGSA-N inositol Chemical compound O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@H](O)[C@@H]1O CDAISMWEOUEBRE-GPIVLXJGSA-N 0.000 description 1
- 239000011229 interlayer Substances 0.000 description 1
- 239000001573 invertase Substances 0.000 description 1
- 235000011073 invertase Nutrition 0.000 description 1
- 230000007794 irritation Effects 0.000 description 1
- MWDZOUNAPSSOEL-UHFFFAOYSA-N kaempferol Natural products OC1=C(C(=O)c2cc(O)cc(O)c2O1)c3ccc(O)cc3 MWDZOUNAPSSOEL-UHFFFAOYSA-N 0.000 description 1
- 150000002576 ketones Chemical class 0.000 description 1
- 229940116108 lactase Drugs 0.000 description 1
- 229940039695 lactobacillus acidophilus Drugs 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- ZLNQQNXFFQJAID-UHFFFAOYSA-L magnesium carbonate Chemical compound [Mg+2].[O-]C([O-])=O ZLNQQNXFFQJAID-UHFFFAOYSA-L 0.000 description 1
- 239000001095 magnesium carbonate Substances 0.000 description 1
- 229910000021 magnesium carbonate Inorganic materials 0.000 description 1
- 235000009973 maize Nutrition 0.000 description 1
- 230000007721 medicinal effect Effects 0.000 description 1
- 244000005700 microbiome Species 0.000 description 1
- 244000005706 microflora Species 0.000 description 1
- 238000003801 milling Methods 0.000 description 1
- 150000002772 monosaccharides Chemical class 0.000 description 1
- 229960003512 nicotinic acid Drugs 0.000 description 1
- 235000001968 nicotinic acid Nutrition 0.000 description 1
- 239000011664 nicotinic acid Substances 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 150000007523 nucleic acids Chemical class 0.000 description 1
- 108020004707 nucleic acids Proteins 0.000 description 1
- 102000039446 nucleic acids Human genes 0.000 description 1
- 238000005457 optimization Methods 0.000 description 1
- 230000001151 other effect Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 230000020477 pH reduction Effects 0.000 description 1
- 229940055726 pantothenic acid Drugs 0.000 description 1
- 235000019161 pantothenic acid Nutrition 0.000 description 1
- 239000011713 pantothenic acid Substances 0.000 description 1
- 235000020232 peanut Nutrition 0.000 description 1
- 235000021017 pears Nutrition 0.000 description 1
- 229920001277 pectin Polymers 0.000 description 1
- 239000001814 pectin Substances 0.000 description 1
- 235000010987 pectin Nutrition 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- 230000008855 peristalsis Effects 0.000 description 1
- 230000002085 persistent effect Effects 0.000 description 1
- ISWSIDIOOBJBQZ-UHFFFAOYSA-N phenol group Chemical group C1(=CC=CC=C1)O ISWSIDIOOBJBQZ-UHFFFAOYSA-N 0.000 description 1
- 150000007965 phenolic acids Chemical class 0.000 description 1
- 230000001766 physiological effect Effects 0.000 description 1
- 235000021110 pickles Nutrition 0.000 description 1
- 239000002574 poison Substances 0.000 description 1
- 235000013824 polyphenols Nutrition 0.000 description 1
- 238000009374 poultry farming Methods 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 238000013139 quantization Methods 0.000 description 1
- 229960001285 quercetin Drugs 0.000 description 1
- 235000005875 quercetin Nutrition 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 230000000717 retained effect Effects 0.000 description 1
- 235000009566 rice Nutrition 0.000 description 1
- 230000005070 ripening Effects 0.000 description 1
- 210000003296 saliva Anatomy 0.000 description 1
- 238000009938 salting Methods 0.000 description 1
- 208000010233 scurvy Diseases 0.000 description 1
- CDAISMWEOUEBRE-UHFFFAOYSA-N scyllo-inosotol Natural products OC1C(O)C(O)C(O)C(O)C1O CDAISMWEOUEBRE-UHFFFAOYSA-N 0.000 description 1
- 238000001179 sorption measurement Methods 0.000 description 1
- 235000019698 starch Nutrition 0.000 description 1
- 230000001954 sterilising effect Effects 0.000 description 1
- 239000004575 stone Substances 0.000 description 1
- 239000010902 straw Substances 0.000 description 1
- 238000005728 strengthening Methods 0.000 description 1
- 238000000859 sublimation Methods 0.000 description 1
- 230000008022 sublimation Effects 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000011580 syndromic disease Diseases 0.000 description 1
- 239000004577 thatch Substances 0.000 description 1
- 210000001519 tissue Anatomy 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
- 210000002700 urine Anatomy 0.000 description 1
- 238000009777 vacuum freeze-drying Methods 0.000 description 1
- 239000010455 vermiculite Substances 0.000 description 1
- 229910052902 vermiculite Inorganic materials 0.000 description 1
- 235000019354 vermiculite Nutrition 0.000 description 1
- 230000035899 viability Effects 0.000 description 1
- 235000019156 vitamin B Nutrition 0.000 description 1
- 239000011720 vitamin B Substances 0.000 description 1
- VHBFFQKBGNRLFZ-UHFFFAOYSA-N vitamin p Natural products O1C2=CC=CC=C2C(=O)C=C1C1=CC=CC=C1 VHBFFQKBGNRLFZ-UHFFFAOYSA-N 0.000 description 1
- 239000002699 waste material Substances 0.000 description 1
- 239000010457 zeolite Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/10—Animal feeding-stuffs obtained by microbiological or biochemical processes
- A23K10/16—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions
- A23K10/18—Addition of microorganisms or extracts thereof, e.g. single-cell proteins, to feeding-stuff compositions of live microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K10/00—Animal feeding-stuffs
- A23K10/30—Animal feeding-stuffs from material of plant origin, e.g. roots, seeds or hay; from material of fungal origin, e.g. mushrooms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23K—FODDER
- A23K20/00—Accessory food factors for animal feeding-stuffs
- A23K20/20—Inorganic substances, e.g. oligoelements
- A23K20/24—Compounds of alkaline earth metals, e.g. magnesium
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K33/00—Medicinal preparations containing inorganic active ingredients
- A61K33/44—Elemental carbon, e.g. charcoal, carbon black
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/57—Birds; Materials from birds, e.g. eggs, feathers, egg white, egg yolk or endothelium corneum gigeriae galli
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/123—Bulgaricus
Abstract
Lactobacillus bulgaricus feed addictive disclosed by the invention, it is characterized in that being uniformly mixed by lactobacillus bulgaricus, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder, the charing egg-shell meal for adding surplus again is uniformly mixed, and composite packaging is made：Lactobacillus bulgaricus 30000 hundred million -150000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 5-50g, Rosa roxburghii freeze-dried powder 5-50g, wintercherry freeze-dried powder 3-30g, blackcurrant freeze-dried powder 3-30g, cactus freeze-dried powder 50-150g, remaining is charing egg-shell meal.Viable bacteria contained by the present invention is clear, application and Quantitatively Selecting conducive to user, using sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus freeze-dried powder and charing egg-shell meal as the matrix of additive, stability, trophism and the adsorptivity of additive institute mycetome can not only be improved, the nutritive value for promoting product simultaneously promotes the metabolism of animal, improves body resistance against diseases, promote growth of animal, the final economic benefit for improving aquaculture.
Description
Technical field
The invention belongs to feed additive fields, are related to a kind of for cultivated animals probiotic feed additive.Specifically
It is related to a kind of lactobacillus bulgaricus feed addictive.
Background technique
Lactic acid bacteria（Lactic acid bacteria, LAB）The lactic acid bacteria being currently known has more than 100 kind.Lactic acid bacteria
Applicating history is very long, such as the production and production of dairy products, pickles, ensilage.In the enteron aisle of humans and animals there is
A large amount of lactic acid bacteria.Lactobacillus preparation is a kind of preparation containing live lactobacillus, entitled alctasin.Lactic acid bacteria grows in enteron aisle
Development decomposes carbohydrate and generates lactic acid and form acidic environment, to inhibit the proliferation of harmful bacteria in intestinal canal, and prevent from producing poison and
It causes a disease.The strain for preparing lactobacillus preparation has lactobacillus acidophilus, lactobacillus bulgaricus, streptococcus lactis and streptococcus fecalis etc..
Lactobacillus is animal（Especially poultry) enteron aisle normal settler.Poultry went out after shell in a few hours can be
Streptococcus fecalis, the enterobacteria that discovery is dispersed in enteron aisle（) and clostridium Enterobateria（Clostridia), with
Bacillus acidi lactici just starts to settle down in alimentary canal in a couple of days afterwards.Lactobacillus is the main Pseudomonas of fowl piperazine capsule flora, with large intestine
Bacillus, streptococcus（Streptococi it) compares and occupies advantage.Bacillus acidi lactici is adhered to fowl prolixity capsular epithelium, and this adhesion has kind
Specificity.Fowl piperazine capsule Bacillus acidi lactici is the Bacillus acidi lactici source that poultry maintains intestinal bacteria balance.Bacillus acidi lactici is maintaining to digest
The aspect of stablizing of the normal microflora system in road plays conclusive effect.Most probiotic products be Lactobacillus or other
Lactic acid-producing bacteria.
Lactic acid bacteria anaerobism or amphimicrobian growth, still are able to survive under pH3.0-4.5 acid condition.It is in animal intestinal tract
Middle by monosaccharide, especially Lactose conversion is lactic acid, to reduce intestinal pH, prevents foreign bacteria in the field planting of enteron aisle, inhibits large intestine
The growth of the pathogens such as bacillus, detection of Salmonella, and the growth of final lactic acid bacteria inhibiting itself.Lactic acid bacteria also can be by adjusting enteron aisle
PH promotes gastrointestinal peristalsis to activate pepsin, helps the digestion of food, absorbs, mitigate flatulence and promote liver function etc..
Lactic acid bacteria is acted on by competitive exclusion（Competitive binding site) inhibit pathogen growth.Lactic acid bacteria can also stimulate siberian crabapple
System improves immunity of organisms, improves intestinal tissue to the resistivity of bacteria attack.Some Bacillus acidi lacticis can neutralize certain toxin,
As lactobacillus bulgaricus can neutralize escherichia coli enterotoxin, but precise mechanism is unclear.Bacillus acidi lactici also can produce itself
Some digestive ferments, such as invertase, lactase and peptase, help to improve animal digestion function.Sawada report, certain lactic acid
Contain a kind of safe and effective natural anti-hypertension compound SG-1 in bacilli-cell wall.Lang Zhongwu is equal to 1994 in egg young bird
Brood of layers chichen is added in daily grain of chicken, as a result feed efficiency improves 8.73%-11.23%；Xiao Zhenfeng etc.（1995) it tries
Verify bright, Brood of layers chichen is compared compared with antibiotic control group, improves feed efficiency 4.6%.Furthermore Bacillus acidi lactici can
The digestive function of small intestine is improved by increasing surface area.Animal is in stress（As birth, wean, daily ration variation, intestinal pH are abnormal
It increases）Period, total variation tendency are that pathogen is increased, and Bacillus acidi lactici quantity is reduced.Lactobacillus is successfully established in enteron aisle
PH can be made to become stable.
The characteristics of lactic acid bacteria is：1. being the main fungal component of many animals alimentary canal, normal flora can be formed：2. in micro- need
Lactic acid is generated under oxygen or anaerobic condition；3. there is stronger acid resistance；4. generating a kind of bacteriocin
（Bacteriocin), hay bacillus, staphylococcic growth can effectively be inhibited.The shortcomings that lactic acid bacteria is that temperature capacity is poor,
Dead under the conditions of 65 ~ 75 DEG C, instantaneous high-temperature can be killed and be failed during feed granules.The type of preparation of such bacterium
It is various, using earliest, most extensively.
Lactobacillus bulgaricus（Lactobacillus bulgaricus）Current entitled Lactobacillus delbrueckii is sub-
Kind, it is that Minister Agriculture of China announces No. 2045 announcement《Feed addictive catalogue（2013）》It is allowed for micro- life of cultivated animals
Object has an aqua and pulvis two major classes with regard to the dosage form that current lactobacillus bulgaricus is used as additive, aqueous solution dosage form because
Nutritional substance in thallus aqua easy to use continues to be metabolized, and growth fermentation, therefore, the thallus of this dosage form are in unstable
State, storage life are shorter.Powder formulation is then that thallus is carried out to the thallus lived using drying means such as low temperature hot wind, freezings
It is dehydrated at a slow speed, thallus is made to be in stable drying dormant state, recycle substance that can be feeding to mix as filler equal
It is even that relatively stable powder-type biological feed additive is made.But with regard to being easy to get and processing in view of raw material of current manufacturing enterprise
Cost often selects rice bran, wheat bran, corn flour, maize cob meal, peanut shell powder, conch meal, vermiculite power, mountain flour, calcium carbonate, wheat meal
One or more of stone, zeolite powder mixture, some also use plant straw powder or grass meal as filler material.These are in line with life
The considerations of producing cost then has ignored the stability of microbial bacteria and the trophism value of feed addictive.
In order in use, have certain adhesion, microbial bacteria feed addictive be made to exist in microbial bacteria additive
It admixes when being mixed in animal feed, can be adsorbed on animal feed, convenient for the uniformity in animal feeding and be fed into bacterium amount
Maximization, some products take pains a certain amount of binder of addition.
In order to make to raise the relative constant of animal stomach inner pH value, acid is continued up to after so that the foodstuff being fed into is entered small intestine
The effect of change, in the product often simultaneously using acidulants such as citric acid, lactic acid, hydrochloric acid, fumaric acid, but these acidulants are not only straight
It connects and locally causes acidity too strong microbial bacteria contained by additive, influence the survival of thallus, meanwhile, these acidifying substances are to cultivation
Animal also without the nutritive value directly utilized, meanwhile, there is very big irritation to the gastrointestinal tract of the cubs of livestock and poultry, chick,
Compatibility is using not ideal enough.
Above-mentioned deficiency can be overcome by developing one kind, can either keep stability, the trophism of institute's mycetome, be had again to thallus
There is adhesion, while having again to the filler used and providing the additive for microbe feedstuff of nutritive value to cultivated animals, is
Promote the basis of feed additive industry long-term stability development.
Summary of the invention
The purpose of the present invention is to provide a kind of new single type lactobacillus bulgaricus feed addictive, the Bulgaria
Not only there is lactobacillus feed addictive thallus to stablize, and the thallus time-to-live is long, and used auxiliary agents have centainly
Adhesiveness and adsorptivity, thallus can be made preferably to be bonding on one with auxiliary agents, meanwhile, complementary additive have one
Fixed acidity can not only provide nutriment abundant, while its acidic materials is able to maintain stomach inner pH value phase after animal feeding
To constant, into small intestine after the effect of continuing up to acidification.The purpose is to provide the guarantor of a kind of more stability and trophism to add
Leah lactobacillus feed addictive.
Lactobacillus bulgaricus feed addictive of the present invention, it is characterized in that by lactobacillus bulgaricus and a certain amount of sea-buckthorn
Powder, Ribes burejense powder, wintercherry powder, blackcurrant powder, cactus powder and charing egg-shell meal uniformly mix, and obtain a kind of new bulgarian milk
Bacillus feed addictive, the thallus of this additive are stablized, and the thallus time-to-live is long, and seabuckthorn fruit powder, Ribes burejense powder, wintercherry powder, black
Gallon powder sugar content is high, and especially cactus powder all has preferable Adhesion property, and charing egg-shell meal also has preferable absorption
Property.Wherein sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant are the ascorbic fruits of high-content, and acidity is extremely strong, not only give cultivated animals
The nutriments such as vitamin abundant are provided, the acidic materials after feeding play the effect for promoting digestion well, thus
The purpose of the present invention is highlighted.
In order to realize the present invention, the following technical solutions are specifically adopted：
Lactobacillus bulgaricus feed addictive, feature it be first by lactobacillus bulgaricus, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze
Dry powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Uniformly, composite packaging is made：Lactobacillus bulgaricus 30000 hundred million -150000 hundred million in every 1000g feed addictive, it is husky
Spine freeze-dried powder 5-50g, Rosa roxburghii freeze-dried powder 5-50g, wintercherry freeze-dried powder 3-30g, blackcurrant freeze-dried powder 3-30g, cactus freeze-dried powder
50-150g, remaining is charing egg-shell meal.
Lactobacillus bulgaricus described above is lactobacillus bulgaricus dry powder product.
The lactobacillus bulgaricus dry powder product can be used commercially available containing as every gram of feed addictive and live
Bacteria concentration is no less than 250 hundred million preparations, the weight of the lactobacillus bulgaricus dry powder product and the filler material in formula
Proportion is determined by the thallus content of thalli dry powder and final products.
It is logical that the lactobacillus bulgaricus dry powder product also can use the culture medium that existing method selection accordingly optimizes
Liquid fermentation equipment culture is crossed, is then separated the thallus in fermentation liquid with high speed centrifugation mode, it is indoor to be placed in drying
Bacterium mud drying is made, every gram of viable bacteria concentration no less than 250 hundred million bacterium of acquisition with vacuum freeze drying mode for cold wind
Soma powder product.
Sea-buckthorn freeze-dried powder described above, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder,
It being made by following methods, technical process is that fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus is taken to remove carpopodium respectively,
The impurity such as rotten fruit, rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；Rinsing condition described above is
With the citric acid of 40 DEG C of water addition weight 0.1%, 15min is rinsed, and be stirred continuously, pulls out to be put into pure water and rinse 3 times；On
Stating freezing is that will be cooled to rapidly -45 DEG C or less after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively；Above-mentioned distillation
Dry process conditions are temperature-22-- 32 DEG C, and vacuum degree 120-150Pa is dry until moisture is less than 6%/w；It is above-mentioned
Low-temperature grinding is the crushing that temperature of charge is in 0 DEG C or less progress, 100 mesh of grinding particle size >.
Composite packaging described above uses interior outer bag composite packaging, and inner bag uses polypropylene plastics pocket, and outer packing uses aluminium
Foil bag is filled with silica-gel desiccant between interior outer bag.
Charing egg-shell meal described above is made by following methods：
（1）Dry, dipping first cleans up eggshell, dries moisture, is dried 1-2 hours, then pulverizes into advance
20-30 mesh coarse powder, by weight 1:0.5 sprays the salt that prepared weight fraction is 25% on eggshell coarse powder（Sodium chloride）
Solution is mixed in sprinkling, is placed after mixing 6-7 hours, then uniformly mixing is primary again, then places 6-7 hours；The purpose is to
Salt is allowed effectively to penetrate into eggshell organization internal gap；
（2）Charing impregnated eggshell powder raw material is put into rotary carbonizing pot, 420-450 DEG C at a temperature of rotate charcoal
Change 70-80 minutes, until observing the complete blackening of raw material（Carbonization process should have corresponding scraping blade, to prevent raw material in carbonization process
Viscous pot and agglomeration）；
（3）The raw material carbonized is rapidly moved in activation furnace by activation, is closed fire door, is passed through carbon dioxide gas, is caught up with to the greatest extent wherein
Air, at 720-800 DEG C anoxybiotic activate 55-85 minutes（Corresponding turning mechanism is set in activation furnace, keeps activation raw material every
It can be stirred within 10 minutes once, to guarantee activation fully and uniformly）；
（4）After activated material is taken out in cleaning, it is allowed to cool room temperature, activated material is gradually rinsed in rinse bath with clear water, until
Until basic inspection does not measure sodium chloride；After having cleaned sodium chloride, it is small that activated material 2.5-3 is submerged with the hydrochloric acid that mass ratio is 12%
When, after impregnating, with 95 DEG C of pure water washing activated materials, until material grain is there is no after white, then with the drift of room temperature pure water
It is washed till neutrality（PH value is about in 6.9-7.1）, filter, obtain rinse activator material；
（5）Dry and screening, which dries the activated material of rinsed clean at 115-120 DEG C to water content, is lower than 6%（w）, cross 60
Mesh, the coarse grain after screening are pulverized again, are made all by 60 meshes to get charing egg-shell meal product.
Drying described above uses heated-air drying or far-infrared ray drying；Dry condition is 180 DEG C -300 DEG C.It is dried
Purpose be that can make the crisp matter of eggshell, increase eggshell hole be conducive to sprinkling saline solution effectively penetrate eggshell internal voids
In.
Eggshell described above is the mixed of any one or a few in egg shell, Ovum Anas domestica putamina, goose egg-shell and quail eggshell
Close eggshell.
The prioritization scheme of lactobacillus bulgaricus feed addictive of the present invention is, first by lactobacillus bulgaricus, sea-buckthorn
Freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charcoal of surplus
Change egg-shell meal to be uniformly mixed, composite packaging is made：The lactobacillus bulgaricus 50000 hundred million-in every 1000g feed addictive
150000 hundred million, sea-buckthorn freeze-dried powder 10-50g, Rosa roxburghii freeze-dried powder 10-50g, wintercherry freeze-dried powder 5-30g, blackcurrant freeze-dried powder 5-
30g, cactus freeze-dried powder 70-150g, remaining is charing egg-shell meal.
The further prioritization scheme of the present invention is lactobacillus bulgaricus feed addictive, it is characterized in that being added first by protecting
Leah lactobacillus, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, the mixing of cactus freeze-dried powder are equal
It is even, then add surplus charing egg-shell meal be uniformly mixed, composite packaging is made：It is Bulgarian in every 1000g feed addictive
Lactobacillus 70000 hundred million -150000 hundred million, sea-buckthorn freeze-dried powder 15-50g, Rosa roxburghii freeze-dried powder 15-50g, wintercherry freeze-dried powder 8-30g,
Blackcurrant freeze-dried powder 8-30g, cactus freeze-dried powder 85-150g, remaining is charing egg-shell meal.
Further optimization plan of the present invention is lactobacillus bulgaricus feed addictive, it is characterized in that first by protecting
Add Leah lactobacillus, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, the mixing of cactus freeze-dried powder equal
It is even, then add surplus charing egg-shell meal be uniformly mixed, composite packaging is made：It is Bulgarian in every 1000g feed addictive
Lactobacillus 90000 hundred million -150000 hundred million, sea-buckthorn freeze-dried powder 20-50g, Rosa roxburghii freeze-dried powder 20-50g, wintercherry freeze-dried powder 10-
30g, blackcurrant freeze-dried powder 10-30g, cactus freeze-dried powder 100-150g, remaining is charing egg-shell meal.
Sea-buckthorn（Hippophae rhamnoides Linn.）, fruit nutriment rich in and biological active matter
Matter can be widely applied to many fields of the national economy such as food, medicine, light industry, space flight, agriculture and animal husbandry fishery.Fructus hippophae and oil
With very high medical value, there is a cough-relieving apophlegmatic, relieving dyspepsia, promoting blood circulation to remove blood stasis effect, can treat gastric duodenal ulcer with
And indigestion etc..
Sea buckthorn fruit is full of nutrition, according to surveying and determination in its fruit containing multivitamin, fatty acid, microelement, sub- oil element,
The various amino acid of Hippophate flavone, superoxides isoreactivity substance and needed by human body.Wherein Vitamin C content is high, and every 100 grams
In fruit juice, Vitamin C content can reach 825-1100 milligrams, is 2-3 times of Kiwi berry, is known as the laudatory title of the king of vitamin C.Contain
Sugared 7.5%-10%, the 3%-5% containing acid.
Rosa roxburghii Tratt（Rosa roxbunghii）For the fruit of the perennial machaka rosa roxburghii of rosaceae also known as mountain king fruit, thorn
Certain kind of berries fruit, thatch pears etc..With clearing heat and promoting fluid, stomach strengthening and digestion promoting, relieving summer-heat and other effects.Rosa roxburghii Tratt vitamin B rich in, C, carrotene,
The ingredients such as malic acid, citric acid are usually used in deficiency of stomach-Yin, appetite stimulator, indigestion or eating accumulation, glutted full bored, diarrhea
Loose stool；Pyreticosis or hot summer weather hurt saliva, thirsty, scanty drak urine.
Mature Rosa roxburghii Tratt is fleshy hypertrophy, sweet and sour, fruit are rich in sugar, vitamin, carrotene, organic acid and more than 20 kinds of ammonia
More than base acid, 10 microelement and superoxide dismutase, especially Vitamin C content beneficial to human body are high, are to work as
It is highest in preceding fruit, it is 50 times of citrus 841.58 milligrams -3541.13 milligrams of content in every 100 grams of fresh fruits, Kiwi berry
10 times, the laudatory title with " king of vitamin C ".Fruit of Grossularia burejensis Berger has very high nutritive value and medical value, sour, puckery, flat,
Digestion-promoting spleen-invigorating restrains stopping leak, for treating having indigestion abdominal distension, dysentery, enteritis, vitamin C deficiency etc..
Wintercherry（Physali alkekengiL.）Also known as groundcherry, franchet groundcherry persistent calyx or fruit, cape gooseberry etc..Containing more in Fruit of Physalis
Kind of nutritional ingredient, wherein the content of calcium be 73.1 times of tomato, 13.8 times of carrot, ascorbic content is tomato
6.4 times, 5.4 times of carrot.With unique flavor and nutrition abundant.Fruit of Physalis aromatic flavour, delicious.Berry is rich
Containing vitamin C, beta carotene, more than 20 kinds of mineral elements and 18 kinds of amino acid, there is heat-clearing, removing toxic substances, diuresis effect is usually used in
Control heat-syndrome cough, pharyngalgia, jaundice, dysentery, in water, the treatment of furunculosis, erysipelas etc..
Blackcurrant scientific name elements of black currant（Ribes nigrum L.）Also known as currant, purple plum etc., ripening fruits are black
Small berries, it is interior to be rich in vitamin C, anthocyanidin.Blackcurrant is not only a kind of delicious flavour, fruit full of nutrition, and has
Good medicinal efficacy.Blackcurrant fruit is rich in mineral matter element, and the Zn content in mineral matter element is high, can be used as and comes for zinc
Source；Ascorbic content is high, hence it is evident that is higher than citrus, hawthorn, also contains phosphorus, magnesium, potassium, calcium, anthocyanidin, phenolic substances.Seed
Linoleic acid content is high.Ascorbic content is very rich in blackcurrant, it is often more important that is also melted into containing a large amount of antioxygen
Point, this assures ascorbic function and effect.Blackcurrant is rich in such as anthocyanidin, vitamin C, flavones, Quercetin, red bayberry
The substances such as alcohol, phenolic acid, catechin and blackcurrant polysaccharide, these are all the bioactive substances with good anti-oxidation function.
Cactus（Scientific name：Opuntia stricta(Haw.)Haw.var.dillenii(Ker-Gawl.) Benson）,
It is a kind of plant of Opuntia.Alias celestial being palm, kwan-yin palm etc..Cactus is the meat shrub that grows thickly, the wide ovum of top branch
Shape, obovate elliptic or subcircular；Flower spoke shape, holder obovate.It is used as medicine with complete stool.The four seasons can adopt.
Cactus is cool in nature, sour, nontoxic.Have the promoting flow of qi and blood circulation, heat-clearing toxin-expelling functions.Mainly have clearing heat and detoxicating, eliminating stasis to subdue swelling,
The functions such as the promoting flow of qi and blood circulation, benefiting stomach and stopping pain.Cactus contains amino acid and various trace elements in needed by human 8, and embraces green
The preciousness ingredient such as lotus, Kok Beattie cents, cholla stem, starches through cactus crude drug and analyzes, contain pectin, polysaccharide and glue exudate.From herb point
From extracting to obtain freidelin ketone（friedelin）, -3 α -ol of freidelin（friedelan-3-α-ol）, taraxerone
（taraxerone）And taraxerol（taraxerol）.
Eggshell, quantity is biggish in China's poultry farming chicken, duck, goose and quail etc., using egg, duck's egg,
As in food processing process, the useless eggshell enormous amount generated is provided according to existing disclosed report for goose egg and quail egg
Material display, the eggshell total amount that a medium-sized city is monthly discarded reach 60-100 tons, and account for egg size by Eggshell weight 11% calculates,
The eggshell that about 1,500,000 tons of the daily output in China, not only pollutes environment, but also waste of resource in this way.Discarded eggshell is integrated
It utilizes, resource utilization can not only be improved and avoids environmental pollution, and be greatly improved the economic benefit and social benefit of enterprise.
Wherein egg shell is in China's yield maximum, and egg shell accounts for the 10-12% in entire egg, by under film, shell on shell
Film and eggshell three parts composition, eggshell is a kind of calcareous hard shell, is located on shell between film and shell lower film.In the change of egg shell
In studying point, minerals account for 95%, and protein 3.3%, moisture 1%, fat 0.03%, remaining is carbohydrate and other have
Machine substance（It certainly, does not include a large amount of remaining egg white in eggshell in the above ingredient）.Eggshell mineral ingredient is mainly
Calcium carbonate accounts for 94% or so, remaining is magnesium carbonate and calcium phosphate, and calcium, phosphorus content account for 34.9% and of eggshell dry matter respectively
0.2%.In eggshell, seven kinds of vitamins and various trace elements and some important enzymes, peptide matters can be measured, he
Although content seldom, be all the substance needed in human body or animal body.
In the prior art, it is replenished the calcium with egg-shell meal, has the product of the grinds after sterilizing by eggshell in people's product, also have
The application of organic calcium is prepared into using primary or secondary clacining method.It is at present most widely in drug, food and nutriment
In preparation, micron order, submicron order and nano level superfine powder are mostly used, is added to various food, nutrition kind, has reached very
Good effect.Application of the eggshell in China's animal-breeding is taken mostly by eggshell cleaning, drying, and milling is added into feed
The method of feeding, since grinding particle size is larger, being absorbed and utilized for animal is poor, can't reach good application effect.
The present invention is to clean eggshell, after high temperature drying, then be made one through spice, charing, activation, cleaning, drying, screening
The adsorbent of kind function admirable, the program not only remains the nutrition that eggshell utilizes, while making the abundant carbonaceous of eggshell, not only right
It is contained it is calcareous form organic calcium, and form the filling substrate with adsorption capacity.
The beneficial effects of the invention are as follows：
（1）Product of the present invention can highlight the viable bacteria content of lactobacillus bulgaricus, significantly improve thallus in closed composite packaging
In survival rate, through batches of products, reserved sample observing 12 months, lactobacillus bulgaricus average viability exist at room temperature
93.7%, and reference substance（The filler of reference substance is wheat bran）In lactobacillus bulgaricus survival rate be 78.2%；The present invention
Product is single type lactobacillus bulgaricus feed addictive, and the specific aim and quantization with application can be provided to producer
Selection, be targetedly easy to use conducive to livestock and poultry.
（2）By sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder and protect
Leah lactobacillus is added to mix, it, can be more due to the stickum in the colloidal substance that these dry powder formulations are rich in, especially cactus
The adhesive effect between additive and feed is increased well, and improves the utilization rate of additive；
（3）By sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus freeze-dried powder high-content amino acid, vitamin, mineral element, more
Sugar.The nutritional ingredients such as the vitamin C of organic acid, especially high-content and various bioactivators, to raising animal immune energy
Power is simultaneously obviously improved meat, Egg Quality, the acidic materials in especially above-mentioned dry powder, utilization, promotion animal to contained microorganism
Digestion all has significant effect；
（4）Due to using Freeze Drying Technique means, enable sea-buckthorn obtained, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus freeze-dried powder
Its active constituent is maximumlly remained, has distinctive sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, the smell of cactus application and taste
Taste, free from extraneous odour add the preference of animal.
（5）Eggshell is first subjected to drying and other treatment through high temperature using charing egg-shell meal, further through spice, charing, activation, clear
It washes, dry and sieves, form a kind of excellent adsorbent, which not only forms absorption to the saccharomycete in product
Power, while making the eggshell after charing that still there is the organic calcium effect of activation, meanwhile, after animal feeding, have well to stomach
The toxin of enteron aisle has suction-operated, has stop dysentery, antidiarrheal effect for the animal of diarrhea and diarrhea, has good active carbon
Medicinal effects.
（6）To the preparation of sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus freeze-dried powder in the present invention, do not remove the peel, deseeding step
Suddenly, it is therefore an objective to by being crushed after freeze-drying, so that its skin and seed is worn into fine powder, make anthocyanidin, oil in its skin and seed
Class, organic acid, bud fragrance substance are retained, and the nutritive value of its freeze-dried powder is promoted.
（7）The present invention is lyophilized using sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus
Powder, matrix of the charing egg-shell meal as additive contain constants such as a large amount of calcium, phosphorus, potassium, sodium, magnesium, zinc and micro in matrix
Element, vitamin C still rich in, anthocyanidin, beta carotene, malic acid, citric acid, protein, amino acid, nucleic acid, Portugal
Grape sugar, lipoidis, carbohydrate, B family vitamin such as B1、B2、B6、B12And the physiological activity such as folic acid, niacin, pantothenic acid, inositol
Substance, not only improves the nutritive value of lactobacillus bulgaricus additive, while promoting the metabolism of animal, improves body
Disease resistance promotes growth of animal, finally improves the economic benefit of its aquaculture.
（8）Product of the present invention uses interior outer bag composite packaging, and interior outer bag interlayer is filled with silica-gel desiccant, and product does not return
Tide, no agglomeration, product is loose, good fluidity, can preferably keep exterior quality and inherent quality.
Operation to not having its technical process stated in detail in the present invention is in the common sense of those skilled in the art
Operation.With regard to the purchase and storage of heretofore described sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant fresh fruit and fresh cactus, the present invention
The construction of people's unit has 20,000 tons of freezer facility, has enough guarantees to storage fresh fruit material.
Specific embodiment
Embodiment 1
The preparation of sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder：
Sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, the cactus for taking fresh mature respectively remove carpopodium, the impurity such as rotten fruit, with containing heavy
40 DEG C of aqueous solutions of 0.1% citric acid are measured, 15min is rinsed under constant stirring and pulls out, be put into pure water and rinse 3 times, pull out
It is drained；It will be moved into refrigerator after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively, be cooled to -45 DEG C rapidly
Below；Respectively by the sea-buckthorn freezed, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus move into lyophilization machine in, sublimation temperature control-
22--32 DEG C, vacuum degree 120-150Pa makes dry materials to moisture < 6%（w）, the time about needs 18 hours, is put into after taking-up
In freezing crusher, control temperature of charge is no more than 0 DEG C, after being crushed to 100 mesh of fineness >, respectively obtains sea-buckthorn freeze-dried powder, thorn
Pears freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder, are fitted into polybag and seal, and are stored in 0 DEG C or less
It is spare in freezer.
Embodiment 2
Carbonize the preparation of egg-shell meal：
Eggshell is cleaned up first, dries moisture, is placed in electric baking case, the heated-air drying 2 hours under the conditions of 200 DEG C,
After taking-up is let cool, 20 mesh coarse powder are pulverized into, by weight 1:0.5 sprays prepared weight ratio on eggshell coarse powder for 25%
Salt solution（That is egg-shell meal：25% salt solution=1:0.5 ratio）, mixed in sprinkling, place 6 hours after mixing, then
Uniformly mixing is primary again, then places 6 hours；Impregnated eggshell powder raw material is put into rotary carbonizing pot, in 420 DEG C of backspins
Turn charing 80 minutes, until observing the complete blackening of raw material（Carbonization process prevents charcoal in being equipped with the scraping blade rotated automatically in charing pot
Raw material glues pot and agglomeration during change）；The raw material carbonized is rapidly moved in activation furnace, CO is passed through2Gas is caught up with therein to the greatest extent
Air, anoxybiotic activates 80 minutes at 760 DEG C（Controllable stirring is set in activation furnace and stirs blade, is made every in activation raw material
It is stirred within 10 minutes once, guarantees activation material fully and uniformly）；After activation, activated material is taken out, is allowed to cool normal
Temperature gradually rinses activated material in rinse bath with clear water, until basic inspection does not measure sodium chloride, has cleaned sodium chloride
Afterwards, it is submerged activated material 2.5 hours with the hydrochloric acid of mass ratio 12%, is finished wait impregnate, with 95 DEG C of pure water washing activated materials, until
Expect that grain filters 7.0 there is no after white, then with room temperature pure water rinse to pH value, obtains rinse activator material；By rinsed clean
Activated material, which is dried at 115 DEG C to water content, is lower than 6%, crosses 60 meshes, and the coarse grain after screening is pulverized again, makes all to pass through
60 meshes are to get charing egg-shell meal product.
Embodiment 3
Carbonize the preparation of egg-shell meal：
Eggshell is cleaned up first, dries moisture, is placed in far-infrared dryer, it is 1 hour dry under the conditions of 300 DEG C, it takes
After letting cool out, 30 mesh coarse powder are pulverized into, by weight 1:0.5 sprays the food that prepared weight ratio is 25% on eggshell coarse powder
Salting liquid（That is egg-shell meal：25% salt solution=1:0.5 ratio）, mixed in sprinkling, place 7 hours after mixing, then again
Uniformly mixing is primary, then places 7 hours；Impregnated eggshell powder raw material is put into rotary carbonizing pot, is rotated at 450 DEG C
Charing 70 minutes, until observing the complete blackening of raw material（Carbonization process prevents from carbonizing in being equipped with the scraping blade rotated automatically in charing pot
Raw material glues pot and agglomeration in the process）；The raw material carbonized is rapidly moved in activation furnace, CO is passed through2Gas catches up with sky therein to the greatest extent
Gas, anoxybiotic activates 55 minutes at 800 DEG C（Controllable stirring is set in activation furnace and stirs blade, is made in activation raw material every 10
Minute is stirred once, guarantees activation material fully and uniformly）；After activation, activated material is taken out, is allowed to cool normal
Temperature gradually rinses activated material in rinse bath with clear water, until basic inspection does not measure sodium chloride, has cleaned sodium chloride
Afterwards, it is submerged activated material 3 hours with the hydrochloric acid of mass ratio 12%, is finished wait impregnate, with 95 DEG C of pure water washing activated materials, until material
Grain filters 7.0 there is no after white, then with room temperature pure water rinse to pH value, obtains rinse activator material；By the work of rinsed clean
Material, which is dried at 120 DEG C to water content, is lower than 6%, crosses 60 meshes, the coarse grain after screening is pulverized again, made all by 60
Mesh is to get charing egg-shell meal product.
Embodiment 4
A kind of lactobacillus bulgaricus feed addictive is by lactobacillus bulgaricus dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze-drying
Powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Even, composite packaging is made：The lactobacillus bulgaricus 30000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 5g, thorn
Pears freeze-dried powder 5g, wintercherry freeze-dried powder 3g, blackcurrant freeze-dried powder 3g, cactus freeze-dried powder 150g, remaining is charing egg-shell meal；Specifically
Production method is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-drying respectively
Powder, cactus freeze-dried powder mix, then lactobacillus bulgaricus dry powder are uniformly admixed, and then add surplus and are made by embodiment 2
Charing egg-shell meal be sufficiently mixed uniformly after, carry out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag is adopted
With aluminium foil bag, between interior outer bag plus a few packet silica-gel desiccants, to prevent water suction.
Embodiment 5
A kind of lactobacillus bulgaricus feed addictive is by lactobacillus bulgaricus dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze-drying
Powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Even, composite packaging is made：The lactobacillus bulgaricus 50000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 50g, thorn
Pears freeze-dried powder 10g, wintercherry freeze-dried powder 5g, blackcurrant freeze-dried powder 5g, cactus freeze-dried powder 85g, remaining is charing egg-shell meal；Specifically
Production method is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-drying respectively
Powder, cactus freeze-dried powder mix, then lactobacillus bulgaricus dry powder are uniformly admixed, and then add surplus and are made by embodiment 2
Charing egg-shell meal be sufficiently mixed uniformly after, carry out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag is adopted
With aluminium foil bag, between interior outer bag plus a few packet silica-gel desiccants, to prevent water suction.
Embodiment 6
A kind of lactobacillus bulgaricus feed addictive is by lactobacillus bulgaricus dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze-drying
Powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Even, composite packaging is made：The lactobacillus bulgaricus 70000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 15g, thorn
Pears freeze-dried powder 50g, wintercherry freeze-dried powder 8g, blackcurrant freeze-dried powder 8g, cactus freeze-dried powder 90g, remaining is charing egg-shell meal；Specifically
Production method is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-drying respectively
Powder, cactus freeze-dried powder mix, then lactobacillus bulgaricus dry powder are uniformly admixed, and then add surplus and are made by embodiment 2
Charing egg-shell meal be sufficiently mixed uniformly after, carry out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag is adopted
With aluminium foil bag, between interior outer bag plus a few packet silica-gel desiccants, to prevent water suction.
Embodiment 7
A kind of lactobacillus bulgaricus feed addictive is by lactobacillus bulgaricus dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze-drying
Powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Even, composite packaging is made：The lactobacillus bulgaricus 90000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 25g, thorn
Pears freeze-dried powder 25g, wintercherry freeze-dried powder 15g, blackcurrant freeze-dried powder 15g, cactus freeze-dried powder 70g, remaining is charing egg-shell meal；Tool
Body production method is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-drying respectively
Powder, cactus freeze-dried powder mix, then lactobacillus bulgaricus dry powder are uniformly admixed, and then add surplus and are made by embodiment 2
Charing egg-shell meal be sufficiently mixed uniformly after, carry out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag is adopted
With aluminium foil bag, between interior outer bag plus a few packet silica-gel desiccants, to prevent water suction.
Embodiment 8
A kind of lactobacillus bulgaricus feed addictive is by lactobacillus bulgaricus dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze-drying
Powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Even, composite packaging is made：The lactobacillus bulgaricus 150000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 10g,
Rosa roxburghii freeze-dried powder 30g, wintercherry freeze-dried powder 15g, blackcurrant freeze-dried powder 15g, cactus freeze-dried powder 75g, remaining is charing egg-shell meal；
Specific production method is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant jelly respectively
Dry powder, cactus freeze-dried powder mix, then lactobacillus bulgaricus dry powder are uniformly admixed, and then add surplus and are made by embodiment 2
After the charing egg-shell meal obtained is sufficiently mixed uniformly, composite packaging is carried out；Composite packaging is inner bag using polypropylene plastics pocket, outer bag
Using aluminium foil bag, a few packet silica-gel desiccants are added between interior outer bag, to prevent water suction.
Embodiment 9
A kind of lactobacillus bulgaricus feed addictive is by lactobacillus bulgaricus dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze-drying
Powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Even, composite packaging is made：The lactobacillus bulgaricus 130000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 40g,
Rosa roxburghii freeze-dried powder 25g, wintercherry freeze-dried powder 20g, blackcurrant freeze-dried powder 20g, cactus freeze-dried powder 80g, remaining is charing egg-shell meal；
Specific production method is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant jelly respectively
Dry powder, cactus freeze-dried powder mix, then lactobacillus bulgaricus dry powder are uniformly admixed, and then add surplus and are made by embodiment 3
After the charing egg-shell meal obtained is sufficiently mixed uniformly, composite packaging is carried out；Composite packaging is inner bag using polypropylene plastics pocket, outer bag
Using aluminium foil bag, a few packet silica-gel desiccants are added between interior outer bag, to prevent water suction.
Embodiment 10
A kind of lactobacillus bulgaricus feed addictive is by lactobacillus bulgaricus dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze-drying
Powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Even, composite packaging is made：The lactobacillus bulgaricus 100000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 25g,
Rosa roxburghii freeze-dried powder 40g, wintercherry freeze-dried powder 30g, blackcurrant freeze-dried powder 30g, cactus freeze-dried powder 90g, remaining is charing egg-shell meal；
Specific production method is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant jelly respectively
Dry powder, cactus freeze-dried powder mix, then lactobacillus bulgaricus dry powder are uniformly admixed, and then add surplus and are made by embodiment 3
After the charing egg-shell meal obtained is sufficiently mixed uniformly, composite packaging is carried out；Composite packaging is inner bag using polypropylene plastics pocket, outer bag
Using aluminium foil bag, a few packet silica-gel desiccants are added between interior outer bag, to prevent water suction.
Embodiment 11
A kind of lactobacillus bulgaricus feed addictive is by lactobacillus bulgaricus dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze-drying
Powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Even, composite packaging is made：The lactobacillus bulgaricus 110000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 50g,
Rosa roxburghii freeze-dried powder 40g, wintercherry freeze-dried powder 15g, blackcurrant freeze-dried powder 15g, cactus freeze-dried powder 80g, remaining is charing egg-shell meal；
Specific production method is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant jelly respectively
Dry powder, cactus freeze-dried powder mix, then lactobacillus bulgaricus dry powder are uniformly admixed, and then add surplus and are made by embodiment 3
After the charing egg-shell meal obtained is sufficiently mixed uniformly, composite packaging is carried out；Composite packaging is inner bag using polypropylene plastics pocket, outer bag
Using aluminium foil bag, a few packet silica-gel desiccants are added between interior outer bag, to prevent water suction.
Embodiment 12
A kind of lactobacillus bulgaricus feed addictive is by lactobacillus bulgaricus dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt freeze-drying
Powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal mixing of surplus
Even, composite packaging is made：The lactobacillus bulgaricus 120000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 50g,
Rosa roxburghii freeze-dried powder 50g, wintercherry freeze-dried powder 10g, blackcurrant freeze-dried powder 10g, cactus freeze-dried powder 100g, remaining is charing eggshell
Powder；Specific production method be weigh embodiment 1 respectively sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, it is black plus
Logical sequence freeze-dried powder, cactus freeze-dried powder mix, then lactobacillus bulgaricus dry powder are uniformly admixed, and then add surplus by embodiment
After 3 charing egg-shell meals obtained are sufficiently mixed uniformly, composite packaging is carried out；Composite packaging is that inner bag uses polypropylene plastics pocket,
Outer bag uses aluminium foil bag, adds a few packet silica-gel desiccants between interior outer bag, to prevent water suction.
Claims (9)
1. lactobacillus bulgaricus feed addictive, feature it be first by lactobacillus bulgaricus, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt
Freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add surplus charing egg-shell meal it is mixed
It closes uniformly, composite packaging is made：Lactobacillus bulgaricus 30000 hundred million -150000 hundred million in every 1000g feed addictive,
Sea-buckthorn freeze-dried powder 5-50g, Rosa roxburghii freeze-dried powder 5-50g, wintercherry freeze-dried powder 3-30g, blackcurrant freeze-dried powder 3-30g, cactus freeze-drying
Powder 50-150g, remaining is charing egg-shell meal；The sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-drying
Powder, cactus freeze-dried powder, are made by following methods, technical process be take respectively fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant,
Cactus removes carpopodium, the impurity such as rotten fruit, and rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；It is above-mentioned
The rinsing condition is to rinse 15min, and be stirred continuously with the citric acid of 40 DEG C of water addition weight 0.1%, pull out be put into it is pure
It is rinsed 3 times in water purification；Above-mentioned freezing is will to be cooled to rapidly -45 after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively
DEG C or less；The process conditions of above-mentioned lyophilization are temperature-22-- 32 DEG C, and vacuum degree 120-150Pa is dried to moisture and is less than
Until 6%/w；The charing egg-shell meal is made by following methods：（1）Dry, dipping first cleans up eggshell, dries in the air
Solid carbon dioxide point is dried 1-2 hours in advance, then pulverizes into 20-30 mesh coarse powder, by weight 1:0.5 sprays on eggshell coarse powder
Spill the salt that prepared weight fraction is 25%（Sodium chloride）Solution mixes in sprinkling, places 6-7 hours after mixing, so
Uniformly mixing is primary again afterwards, then places 6-7 hours；The purpose is to allow salt effectively to penetrate into eggshell organization internal gap；
（2）Impregnated eggshell powder raw material is put into rotary carbonizing pot by charing, carbonizes 70- in 420-450 DEG C of at a temperature of rotation
80 minutes, until observing the complete blackening of raw material；（3）The raw material carbonized is rapidly moved in activation furnace by activation, closes fire door,
It is passed through carbon dioxide gas, catches up with air therein to the greatest extent, anoxybiotic activates 55-85 minutes at 720-800 DEG C；（4）Cleaning, which is taken out, lives
After material, it is allowed to cool room temperature, activated material is gradually rinsed in rinse bath with clear water, does not measure sodium chloride until examining substantially
Until；After having cleaned sodium chloride, submerged activated material 2.5-3 hours with the hydrochloric acid that mass ratio is 12%, after impregnating, with 95
DEG C pure water washing activated material until material grain is there is no after white, then uses room temperature pure water rinse to neutrality, filters, must rinse
Activated material；（5）Dry and screening, which dries the activated material of rinsed clean at 115-120 DEG C to water content, is lower than 6%/w, mistake
60 meshes, the coarse grain after screening are pulverized again, make all by 60 meshes to get.
2. lactobacillus bulgaricus feed addictive, feature it be first by lactobacillus bulgaricus, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt
Freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add surplus charing egg-shell meal it is mixed
It closes uniformly, composite packaging is made：Lactobacillus bulgaricus 50000 hundred million -150000 hundred million in every 1000g feed addictive,
Sea-buckthorn freeze-dried powder 10-50g, Rosa roxburghii freeze-dried powder 10-50g, wintercherry freeze-dried powder 5-30g, blackcurrant freeze-dried powder 5-30g, cactus are frozen
Dry powder 70-150g, remaining is charing egg-shell meal；The sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze
Dry powder, cactus freeze-dried powder, are made by following methods, technical process be take respectively fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, it is black plus
Logical sequence, cactus remove carpopodium, the impurity such as rotten fruit, and rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；On
Stating the rinsing condition is the citric acid that weight 0.1% is added with 40 DEG C of water, rinses 15min, and be stirred continuously, pulls out and be put into
It is rinsed 3 times in pure water；Above-mentioned freezing be will be cooled to rapidly after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively-
45 DEG C or less；The process conditions of above-mentioned lyophilization are temperature-22-- 32 DEG C, and vacuum degree 120-150Pa is dry small to moisture
Until 6%/w；The charing egg-shell meal is made by following methods：（1）Dry, dipping first cleans up eggshell,
Moisture is dried, is dried 1-2 hours in advance, then pulverizes into 20-30 mesh coarse powder, by weight 1:0.5 on eggshell coarse powder
Spray the salt that prepared weight fraction is 25%（Sodium chloride）Solution is mixed in sprinkling, is placed 6-7 hours after mixing,
Then uniformly mixing is primary again, then places 6-7 hours；The purpose is to allow salt effectively to penetrate into eggshell organization internal gap
In；（2）Impregnated eggshell powder raw material is put into rotary carbonizing pot by charing, in 420-450 DEG C of at a temperature of rotation charing
70-80 minutes, until observing the complete blackening of raw material；（3）The raw material carbonized is rapidly moved in activation furnace by activation, closes furnace
Door, is passed through carbon dioxide gas, catches up with air therein to the greatest extent, and anoxybiotic activates 55-85 minutes at 720-800 DEG C；（4）Cleaning takes
Out after activated material, it is allowed to cool room temperature, activated material is gradually rinsed in rinse bath with clear water, does not measure chlorine until examining substantially
Until changing sodium；After having cleaned sodium chloride, submerged activated material 2.5-3 hours with the hydrochloric acid that mass ratio is 12%, after impregnating,
With 95 DEG C of pure water washing activated materials, until material grain is there is no after white, then room temperature pure water rinse to neutrality is used, filter, obtain
Rinse activator material；（5）It is dry and sieve the activated material of rinsed clean is dried at 115-120 DEG C to water content lower than 6%/
W crosses 60 meshes, and the coarse grain after screening pulverized again, make all by 60 meshes to get.
3. lactobacillus bulgaricus feed addictive, feature it be first by lactobacillus bulgaricus, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt
Freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add surplus charing egg-shell meal it is mixed
It closes uniformly, composite packaging is made：Lactobacillus bulgaricus 70000 hundred million -150000 hundred million in every 1000g feed addictive,
Sea-buckthorn freeze-dried powder 15-50g, Rosa roxburghii freeze-dried powder 15-50g, wintercherry freeze-dried powder 8-30g, blackcurrant freeze-dried powder 8-30g, cactus are frozen
Dry powder 85-150g, remaining is charing egg-shell meal；The sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze
Dry powder, cactus freeze-dried powder, are made by following methods, technical process be take respectively fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, it is black plus
Logical sequence, cactus remove carpopodium, the impurity such as rotten fruit, and rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；On
Stating the rinsing condition is the citric acid that weight 0.1% is added with 40 DEG C of water, rinses 15min, and be stirred continuously, pulls out and be put into
It is rinsed 3 times in pure water；Above-mentioned freezing be will be cooled to rapidly after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively-
45 DEG C or less；The process conditions of above-mentioned lyophilization are temperature-22-- 32 DEG C, and vacuum degree 120-150Pa is dry small to moisture
Until 6%/w；The charing egg-shell meal is made by following methods：（1）Dry, dipping first cleans up eggshell,
Moisture is dried, is dried 1-2 hours in advance, then pulverizes into 20-30 mesh coarse powder, by weight 1:0.5 on eggshell coarse powder
Spray the salt that prepared weight fraction is 25%（Sodium chloride）Solution is mixed in sprinkling, is placed 6-7 hours after mixing,
Then uniformly mixing is primary again, then places 6-7 hours；The purpose is to allow salt effectively to penetrate into eggshell organization internal gap
In；（2）Impregnated eggshell powder raw material is put into rotary carbonizing pot by charing, in 420-450 DEG C of at a temperature of rotation charing
70-80 minutes, until observing the complete blackening of raw material；（3）The raw material carbonized is rapidly moved in activation furnace by activation, closes furnace
Door, is passed through carbon dioxide gas, catches up with air therein to the greatest extent, and anoxybiotic activates 55-85 minutes at 720-800 DEG C；（4）Cleaning takes
Out after activated material, it is allowed to cool room temperature, activated material is gradually rinsed in rinse bath with clear water, does not measure chlorine until examining substantially
Until changing sodium；After having cleaned sodium chloride, submerged activated material 2.5-3 hours with the hydrochloric acid that mass ratio is 12%, after impregnating,
With 95 DEG C of pure water washing activated materials, until material grain is there is no after white, then room temperature pure water rinse to neutrality is used, filter, obtain
Rinse activator material；（5）It is dry and sieve the activated material of rinsed clean is dried at 115-120 DEG C to water content lower than 6%/
W crosses 60 meshes, and the coarse grain after screening pulverized again, make all by 60 meshes to get.
4. lactobacillus bulgaricus feed addictive, feature it be first by lactobacillus bulgaricus, sea-buckthorn freeze-dried powder, Rosa roxburghii Tratt
Freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add surplus charing egg-shell meal it is mixed
It closes uniformly, composite packaging is made：Lactobacillus bulgaricus 90000 hundred million -150000 hundred million in every 1000g feed addictive,
Sea-buckthorn freeze-dried powder 20-50g, Rosa roxburghii freeze-dried powder 20-50g, wintercherry freeze-dried powder 10-30g, blackcurrant freeze-dried powder 10-30g, cactus
Freeze-dried powder 100-150g, remaining is charing egg-shell meal；The sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant
Freeze-dried powder, cactus freeze-dried powder, are made by following methods, and technical process is to take fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, black respectively
Gallon, cactus remove carpopodium, the impurity such as rotten fruit, and rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；
Rinsing condition described above is the citric acid that weight 0.1% is added with 40 DEG C of water, rinses 15min, and be stirred continuously, pulls out and put
Enter in pure water and rinses 3 times；Above-mentioned freezing is will to cool down rapidly after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively
To -45 DEG C or less；The process conditions of above-mentioned lyophilization are temperature-22-- 32 DEG C, and vacuum degree 120-150Pa is dry to water
Divide until being less than 6%/w；The charing egg-shell meal is made by following methods：（1）Dry, dipping first cleans eggshell
Completely, moisture is dried, is dried 1-2 hours in advance, then pulverizes into 20-30 mesh coarse powder, by weight 1:0.5 is thick in eggshell
The salt that prepared weight fraction is 25% is sprayed on powder（Sodium chloride）Solution, mixes in sprinkling, and it is small that 6-7 is placed after mixing
When, then uniformly mixing is primary again, then places 6-7 hours；It is empty the purpose is to allow salt effectively to penetrate into eggshell organization internal
In gap；（2）Charing impregnated eggshell powder raw material is put into rotary carbonizing pot, 420-450 DEG C at a temperature of rotate charcoal
Change 70-80 minutes, until observing the complete blackening of raw material；（3）The raw material carbonized is rapidly moved in activation furnace by activation, is closed
Fire door is passed through carbon dioxide gas, catches up with air therein to the greatest extent, and anoxybiotic activates 55-85 minutes at 720-800 DEG C；（4）Cleaning
After taking out activated material, it is allowed to cool room temperature, activated material is gradually rinsed in rinse bath with clear water, is not measured until examining substantially
Until sodium chloride；After having cleaned sodium chloride, is submerged activated material 2.5-3 hours with the hydrochloric acid that mass ratio is 12%, finished wait impregnate
Afterwards, with 95 DEG C of pure water washing activated materials, until material grain is there is no after white, then room temperature pure water rinse to neutrality is used, filtered,
Obtain rinse activator material；（5）Dry and screening, which dries the activated material of rinsed clean at 115-120 DEG C to water content, to be lower than
6%/w crosses 60 meshes, and the coarse grain after screening pulverized again, make all by 60 meshes to get.
5. the lactobacillus bulgaricus feed addictive as described in claim 1-4, which is characterized in that the bulgarian milk
The thalli dry powder product that bacillus is every gram of viable bacteria concentration no less than 250 hundred million.
6. the lactobacillus bulgaricus feed addictive as described in claim 1-4, which is characterized in that the low-temperature grinding is
Temperature of charge is in 0 DEG C or less and is crushed.
7. the lactobacillus bulgaricus feed addictive as described in claim 1-4, which is characterized in that the composite packaging is adopted
With interior outer bag composite packaging, inner bag uses polypropylene plastics pocket, and outer packing uses aluminium foil bag, it is dry that silica gel is filled between interior outer bag
Drying prescription pouch.
8. the lactobacillus bulgaricus feed addictive as described in claim 1-4, which is characterized in that the eggshell is egg
Any one or a few mixing eggshell in shell, Ovum Anas domestica putamina, goose egg-shell and quail eggshell.
9. the lactobacillus bulgaricus feed addictive as described in claim 1-4, which is characterized in that described is dry using heat
Air-dry dry or far-infrared ray drying；The drying condition is 180 DEG C -300 DEG C.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810512030.9A CN108850507A (en) | 2018-05-25 | 2018-05-25 | Lactobacillus bulgaricus feed addictive |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810512030.9A CN108850507A (en) | 2018-05-25 | 2018-05-25 | Lactobacillus bulgaricus feed addictive |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN108850507A true CN108850507A (en) | 2018-11-23 |
Family
ID=64333655
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810512030.9A Withdrawn CN108850507A (en) | 2018-05-25 | 2018-05-25 | Lactobacillus bulgaricus feed addictive |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108850507A (en) |
-
2018
- 2018-05-25 CN CN201810512030.9A patent/CN108850507A/en not_active Withdrawn
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN108850500A (en) | Bacillus pumilus feed addictive | |
| CN108850485A (en) | Bifidobacterium pseudolongum feed addictive | |
| CN108850490A (en) | A kind of Pediococcus pentosaceus feed addictive | |
| CN108850507A (en) | Lactobacillus bulgaricus feed addictive | |
| CN108850506A (en) | Bacteroides succinogenes feed addictive | |
| CN108850514A (en) | Bacteroides amylophilus feed addictive | |
| CN108850499A (en) | Propionibacterium freudenreichii feed addictive | |
| CN108850508A (en) | Xie Shi Propionibacterium feed addictive | |
| CN108850509A (en) | Lactobacillus cellobiosas feed addictive | |
| CN108850520A (en) | Pediococcus acidilactici feed addictive | |
| CN108850497A (en) | Lactobacillus reuteri feed addictive | |
| CN108850524A (en) | Lactobacillus casei feed addictive | |
| CN108850526A (en) | Diacetyl streptococcus lactis feed addictive | |
| CN108850523A (en) | Lactobacillus fermenti feed addictive | |
| CN108902454A (en) | Pediococcus pentosaceus feed addictive | |
| CN108850505A (en) | Lactobacillus plantarum feed addictive | |
| CN108850516A (en) | Lactobacillus brevis feed addictive | |
| CN108850518A (en) | Lactobacillus plantarum feed addictive | |
| CN108850510A (en) | Lactobacillus curvatus feed addictive | |
| CN108850511A (en) | Lactobacillus acidophilus feed addictive | |
| CN108850522A (en) | Streptococcus lactis feed addictive | |
| CN108850519A (en) | Lactobacillus helveticus feed addictive | |
| CN108850512A (en) | Streptococcus thermophilus feed addictive | |
| CN109007272A (en) | Lactobacillus lactis feed addictive | |
| CN108541816A (en) | A kind of feeding complex microorganism additive |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20181123 |
|
| WW01 | Invention patent application withdrawn after publication |