CN108850482A - Bifidobacterium longum feed addictive - Google Patents
Bifidobacterium longum feed addictive Download PDFInfo
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- CN108850482A CN108850482A CN201810511925.0A CN201810511925A CN108850482A CN 108850482 A CN108850482 A CN 108850482A CN 201810511925 A CN201810511925 A CN 201810511925A CN 108850482 A CN108850482 A CN 108850482A
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- freeze
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- blackcurrant
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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Abstract
Bifidobacterium longum feed addictive disclosed by the invention, it is characterized in that being uniformly mixed by bifidobacterium longum, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder, the charing egg-shell meal for adding surplus again is uniformly mixed, and composite packaging is made：Bifidobacterium longum 10000 hundred million -120000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 5-50g, Rosa roxburghii freeze-dried powder 5-50g, wintercherry freeze-dried powder 3-30g, blackcurrant freeze-dried powder 3-30g, cactus freeze-dried powder 50-150g, remaining is charing egg-shell meal.Viable bacteria contained by the present invention is clear, application and Quantitatively Selecting conducive to user, using sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus freeze-dried powder and charing egg-shell meal as the matrix of additive, stability, trophism and the adsorptivity of additive institute mycetome can not only be improved, the nutritive value for promoting product simultaneously promotes the metabolism of animal, improves body resistance against diseases, promote growth of animal, the final economic benefit for improving aquaculture.
Description
Technical field
The invention belongs to feed additive fields, are related to a kind of Bifidobacterium feed addictive for cultivated animals.Tool
Body is related to a kind of bifidobacterium longum feed addictive.
Background technique
Bifidobacterium was separated in 1899 by Tissier for the first time, was a kind of Grain-positive bacillus.The bifid bar being currently known
There is more than 30 kind in Pseudomonas.It is compared with lactic acid bacteria, Bifidobacterium has the following disadvantages：（1）Nutritional ingredient is required strictly and multiple
It is miscellaneous, it must could be grown containing auxin or yeast extract in culture medium；（2）Anaerobic condition is more stringent；（3）In the low environment of pH
The lower time-to-live is short.Bifidobacterium can make carbohydrate fermentation, generate a large amount of acetic acid and lactic acid, to inhibit to have potential pathogenic
Enterobacteria etc. growth and breeding, progressively reach the balance of enteric microorganism bacterium.When animal feeding environment, feed, disease, abuse
The reasons such as antibiotic and reduce bifidobacteria, when intestinal flora being caused to lack of proper care, pathogenic bacteria will take advantage of a weak point, great Liang Fan
It grows, secretes endotoxin, cause disease finally, by taking Bifidobacterium living, so that it settled down, bred in enteron aisle, can promote
It is balanced into maintenance intestinal microecology, achievees the purpose that treatment, health care.Its Bifidobacterium of document report disclosed in the country at present
Pharmacological action is as follows：1. Bifidobacterium can be made to be colonized in intestinal mucosa rapidly, and microorganism is formed in conjunction with intestinal epithelial cell
Film prevents the field planting and invasion of pathogenic bacteria；A large amount of lactic acid and acetic acid are generated, improves enteral environment, maintains normal enterocinesia,
Pathogenic bacteria are promoted to excrete；Directly inhibition or antagonism shigella dysenteriae, typhoid bacillus, Pseudomonas aeruginosa, enteropathogenic E. Coli, Portugal
The growth of the pathogenic bacteria such as grape coccus.2. removing the poisonous and harmful metabolite that pathogenic bacteria are discharged, endotoxin source is reduced；Inhibit
Pathogenic flora growth, reduces level of endotoxin in blood, adjusts microecological balance, prevents and treats endotoxemia.3. a variety of dimensions can be synthesized
Raw element（Such as vitamin B1, B2, B6, B12, niacin, folic acid）And biological enzyme；It is acidified enteron aisle, is conducive to iron, calcium and vitamin
The absorption of D prevents the generation of hypoferric anemia and vitamin D deficiency；A variety of amino acid and microelement can be supplemented.4. can swash
The phagocytic activity of body phagocyte living, enhances the anti pathologic immunity function of body.Carcinogen is removed, reduces to test and move 5. having
The effect of the tumor incidence of object.6. free radical and lipid peroxide can be removed, delay the aging of cell；Reduce harmful substance
Source promotes the ammonia in blood to shift and be discharged to enteral, mitigates the injured possibilities of vitals such as the heart, liver, kidney, delay it
Ageing process.It can be used for the treatment of indigestion, constipation, enteritis, diarrhea etc.；Intestine dysbacteriosis caused by a variety of causes and thus
The prevention and treatment of caused a variety of diseases such as suprainfection, autogenous infection etc..
Bifidobacterium longum is that Minister Agriculture of China announces No. 2045 announcement《Feed addictive catalogue（2013）》Allow to use
There are aqua and pulvis two major classes with regard to the dosage form that current bifidobacterium longum is used as additive in the microbial bacteria of cultivated animals,
Its aqueous solution dosage form is because the nutritional substance in thallus aqua easy to use continues to be metabolized, growth fermentation, therefore, this dosage form
Thallus plays pendulum, and storage life is shorter.Powder formulation is then that the thallus lived is utilized the dry hand such as low temperature hot wind, freezing
Section, thallus or gemma are dehydrated at a slow speed, and thallus is made to be in stable drying dormant state, recycle substance that can be feeding
It is uniformly mixed as filler and relatively stable powder-type biological feed additive is made.But current manufacturing enterprise is considered
Raw material be easy to get and processing cost, often select rice bran, wheat bran, corn flour, maize cob meal, peanut shell powder, conch meal, vermiculite
One or more of powder, mountain flour, calcium carbonate, medical stone, zeolite powder mixture, some are also made using plant straw powder or grass meal
For filler material.The considerations of these are in line with production cost then has ignored the stability of microbial bacteria and the trophism of feed addictive
Value.
In order in use, have certain adhesion, microbial bacteria feed addictive be made to exist in microbial bacteria additive
It admixes when being mixed in animal feed, can be adsorbed on animal feed, convenient for the uniformity in animal feeding and be fed into bacterium amount
Maximization, some products take pains a certain amount of binder of addition.
In order to make to raise the relative constant of animal stomach inner pH value, acid is continued up to after so that the foodstuff being fed into is entered small intestine
The effect of change, in the product often simultaneously using acidulants such as citric acid, lactic acid, hydrochloric acid, fumaric acid, but these acidulants are not only straight
It connects and locally causes acidity too strong microbial bacteria contained by additive, influence the survival of thallus, meanwhile, these acidifying substances are to cultivation
Animal also without the nutritive value directly utilized, meanwhile, there is very big irritation to the gastrointestinal tract of the cubs of livestock and poultry, young fowl,
Compatibility is using not ideal enough.
Above-mentioned deficiency can be overcome by developing one kind, can either keep stability, the trophism of institute's mycetome, be had again to thallus
There is adhesion, while having again to the filler used and providing the additive for microbe feedstuff of nutritive value to cultivated animals, is
Promote the basis of feed additive industry long-term stability development.
Summary of the invention
The purpose of the present invention is to provide a kind of new single type bifidobacterium longum feed addictive, which is raised
Not only there is feed additives thallus to stablize, and the thallus time-to-live is long, and used auxiliary agents have certain adhesiveness
And adsorptivity, thallus can be made preferably to be bonding on one with auxiliary agents, meanwhile, complementary additive has certain acid
Property can not only provide nutriment abundant after animal feeding, while to be able to maintain stomach inner pH value relatively permanent for its acidic materials
It is fixed, into small intestine after the effect of continuing up to acidification.The purpose is to provide the long bifid bar of a kind of more stability and trophism
Bacterium feed addictive.The Ministry of Agriculture of bifidobacterium longum China announces No. 2046《Feed addictive catalogue（2013）》Announcing allows
The microorganism used.And Food and Drug Administration and feed management association are considered safe microorganism fodder, therefore
The development and application of bifidobacterium longum feed addictive are safe.
Bifidobacterium longum feed addictive of the present invention, it is characterized in that by bifidobacterium longum and a certain amount of seabuckthorn fruit powder, Rosa roxburghii Tratt
Powder, wintercherry powder, blackcurrant powder, cactus powder and charing egg-shell meal uniformly mix, and obtain the new bifidobacterium longum feed of one kind and add
Add agent, the thallus of this additive is stablized, and the thallus time-to-live is long, and seabuckthorn fruit powder, Ribes burejense powder, wintercherry powder, blackcurrant powder are containing sugar
Amount is high, and especially cactus powder all has preferable Adhesion property, and charing egg-shell meal also has preferable adsorptivity.It is wherein husky
Spine, Rosa roxburghii Tratt, wintercherry, blackcurrant are the ascorbic fruits of high-content, not only provide the battalion such as vitamin abundant to cultivated animals
Substance is supported, the acidic materials after feeding in fruit powder play the effect for promoting digestion well, to highlight of the invention
Purpose.
In order to realize the present invention, the following technical solutions are specifically adopted：
Bifidobacterium longum feed addictive, feature it be first by bifidobacterium longum, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, acid
It starches freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder to be uniformly mixed, then adds the charing egg-shell meal of surplus and be uniformly mixed, it is multiple
Packaging is closed to be made：Bifidobacterium longum 10000 hundred million -120000 hundred million, sea-buckthorn freeze-dried powder 5- in every 1000g feed addictive
50g, Rosa roxburghii freeze-dried powder 5-50g, wintercherry freeze-dried powder 3-30g, blackcurrant freeze-dried powder 3-30g, cactus freeze-dried powder 50-150g,
Remaining is charing egg-shell meal.
Bifidobacterium longum described above is bifidobacterium longum dry powder product.
The bifidobacterium longum dry powder product, can be used it is commercially available be used as every gram of feed addictive it is dense containing viable bacteria
The weight proportion of the preparation that degree is no less than 200 hundred million, the bifidobacterium longum dry powder product and the filler material in formula is by bacterium
The thallus content of soma powder and final products determines.
The bifidobacterium longum dry powder product also can use the culture medium that existing method selection accordingly optimizes and pass through liquid
Then body Zymolysis Equipment culture is separated the thallus in fermentation liquid with high speed centrifugation mode, be placed in dry indoor cold wind
Or bacterium mud drying is made with vacuum freeze drying mode, every gram of viable bacteria concentration no less than 200 hundred million thallus of acquisition are dry
Powder product.
Sea-buckthorn freeze-dried powder described above, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder,
It being made by following methods, technical process is that fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus is taken to remove carpopodium respectively,
The impurity such as rotten fruit, rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；Rinsing condition described above is
With the citric acid of 40 DEG C of water addition weight 0.1%, 15min is rinsed, and be stirred continuously, pulls out to be put into pure water and rinse 3 times；On
Stating freezing is that will be cooled to rapidly -45 DEG C or less after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively；Above-mentioned distillation
Dry process conditions are temperature-22-- 32 DEG C, and vacuum degree 120-150Pa is dry until moisture is less than 6%/w；It is above-mentioned
Low-temperature grinding is the crushing that temperature of charge is in 0 DEG C or less progress, 100 mesh of grinding particle size >.
Composite packaging described above uses interior outer bag composite packaging, and inner bag uses polypropylene plastics pocket, and outer packing uses aluminium
Foil bag is filled with silica-gel desiccant pouch between interior outer bag.
Charing egg-shell meal described above is made by following methods：
（1）Dry, dipping first cleans up eggshell, dries moisture, is dried 1-2 hours, then pulverizes into advance
20-30 mesh coarse powder, by weight 1:0.5 sprays the salt that prepared weight fraction is 25% on eggshell coarse powder（Sodium chloride）
Solution is mixed in sprinkling, is placed after mixing 6-7 hours, then uniformly mixing is primary again, then places 6-7 hours；The purpose is to
Salt is allowed effectively to penetrate into eggshell organization internal gap；
（2）Charing impregnated eggshell powder raw material is put into rotary carbonizing pot, 420-450 DEG C at a temperature of rotate charcoal
Change 70-80 minutes, until observing the complete blackening of raw material（Carbonization process should have corresponding scraping blade, to prevent raw material in carbonization process
Viscous pot and agglomeration）；
（3）The raw material carbonized is rapidly moved in activation furnace by activation, is closed fire door, is passed through carbon dioxide gas, is caught up with to the greatest extent wherein
Air, at 720-800 DEG C anoxybiotic activate 55-85 minutes（Corresponding turning mechanism is set in activation furnace, keeps activation raw material every
It can be stirred within 10 minutes once, to guarantee activation fully and uniformly）；
（4）After activated material is taken out in cleaning, it is allowed to cool room temperature, activated material is gradually rinsed in rinse bath with clear water, until
Until basic inspection does not measure sodium chloride；After having cleaned sodium chloride, it is small that activated material 2.5-3 is submerged with the hydrochloric acid that mass ratio is 12%
When, after impregnating, with 95 DEG C of pure water washing activated materials, until material grain is there is no after white, then with the drift of room temperature pure water
It is washed till neutrality（PH value is about in 6.9-7.1）, filter, obtain rinse activator material；
（5）Dry and screening, which dries the activated material of rinsed clean at 115-120 DEG C to water content, is lower than 6%（w）, cross 60
Mesh, the coarse grain after screening are pulverized again, are made all by 60 meshes to get charing egg-shell meal product.
Drying described above uses heated-air drying or far-infrared ray drying；Dry condition is 180 DEG C -300 DEG C.It is dried
Purpose be that can make the crisp matter of eggshell, increase eggshell hole be conducive to sprinkling saline solution effectively penetrate eggshell internal voids
In.
Eggshell described above is the mixed of any one or a few in egg shell, Ovum Anas domestica putamina, goose egg-shell and quail eggshell
Close eggshell.
The prioritization scheme of bifidobacterium longum feed addictive of the present invention is, first by bifidobacterium longum, sea-buckthorn freeze-dried powder, thorn
Pears freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add the charing egg-shell meal of surplus
It is uniformly mixed, composite packaging is made：Bifidobacterium longum 30000 hundred million -120000 hundred million in every 1000g feed addictive, it is husky
Spine freeze-dried powder 10-50g, Rosa roxburghii freeze-dried powder 8-50g, wintercherry freeze-dried powder 5-30g, blackcurrant freeze-dried powder 5-30g, cactus freeze-dried powder
70-150g, remaining is charing egg-shell meal.
The further prioritization scheme of the present invention is bifidobacterium longum feed addictive, it is characterized in that first by long bifid bar
Bacterium, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add
The charing egg-shell meal of surplus is uniformly mixed, and composite packaging is made：The bifidobacterium longum 50000 in every 1000g feed addictive
Hundred million -120000 hundred million, sea-buckthorn freeze-dried powder 15-50g, Rosa roxburghii freeze-dried powder 12-50g, wintercherry freeze-dried powder 8-30g, blackcurrant freeze-dried powder
8-30g, cactus freeze-dried powder 85-150g, remaining is charing egg-shell meal.
Further optimization plan of the present invention is bifidobacterium longum feed addictive, it is characterized in that first by long bifid
Bacillus, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder are uniformly mixed, then add
The charing egg-shell meal of surplus is added to be uniformly mixed, composite packaging is made：The bifidobacterium longum 80000 in every 1000g feed addictive
A hundred million -120000 hundred million, sea-buckthorn freeze-dried powder 20-50g, Rosa roxburghii freeze-dried powder 15-50g, wintercherry freeze-dried powder 10-30g, blackcurrant freeze-drying
Powder 10-30g, cactus freeze-dried powder 100-150g, remaining is charing egg-shell meal.
Bifidobacterium longum can produce lactic acid and acetic acid after fermenting in animal intestine, can improve the utilization rate of calcium, phosphorus, iron, promote
Into the absorption of iron and vitamin D.Bifidobacterium fermentation lactose generate galactolipin, be constitute cerebral nervous system in it is cerebronic at
Point.Bifidobacterium can produce the nutrients such as vitamin B1, B2, B6, B12 and alanine, valine, aspartic acid and threonine
Matter.Bifidobacterium longum can be used for zooprophylazis and treatment bacterial diarrhea.Bifidobacterium longum be Food and Drug Administration and
Feed management association is considered safe microorganism fodder.The Ministry of Agriculture of China announces No. 2045《Feed addictive catalogue
（2013）》Also it records, is used for animal-breeding microbial bacteria.
Sea-buckthorn（Hippophae rhamnoides Linn.）, fruit nutriment rich in and biological active matter
Matter can be widely applied to many fields of the national economy such as food, medicine, light industry, space flight, agriculture and animal husbandry fishery.Fructus hippophae and oil
With very high medical value, there is a cough-relieving apophlegmatic, relieving dyspepsia, promoting blood circulation to remove blood stasis effect, can treat gastric duodenal ulcer with
And indigestion etc..
Sea buckthorn fruit is full of nutrition, according to surveying and determination in its fruit containing multivitamin, fatty acid, microelement, sub- oil element,
The various amino acid of Hippophate flavone, superoxides isoreactivity substance and needed by human body.Wherein Vitamin C content is high, and every 100 grams
In fruit juice, Vitamin C content can reach 825-1100 milligrams, is 2-3 times of Kiwi berry, is known as the laudatory title of the king of vitamin C.Contain
Sugared 7.5%-10%, the 3%-5% containing acid.
Rosa roxburghii Tratt（Rosa roxbunghii）For the fruit of the perennial machaka rosa roxburghii of rosaceae also known as mountain king fruit, thorn
Certain kind of berries fruit, thatch pears etc..With clearing heat and promoting fluid, stomach strengthening and digestion promoting, relieving summer-heat and other effects.Rosa roxburghii Tratt vitamin B rich in, C, carrotene,
The ingredients such as malic acid, citric acid are usually used in deficiency of stomach-Yin, appetite stimulator, indigestion or eating accumulation, glutted full bored, diarrhea
Loose stool；Pyreticosis or hot summer weather hurt saliva, thirsty, scanty drak urine.
Mature Rosa roxburghii Tratt is fleshy hypertrophy, sweet and sour, fruit are rich in sugar, vitamin, carrotene, organic acid and more than 20 kinds of ammonia
More than base acid, 10 microelement and superoxide dismutase, especially Vitamin C content beneficial to human body are high, are to work as
It is highest in preceding fruit, it is 50 times of citrus 841.58 milligrams -3541.13 milligrams of content in every 100 grams of fresh fruits, Kiwi berry
10 times, the laudatory title with " king of vitamin C ".Fruit of Grossularia burejensis Berger has very high nutritive value and medical value, sour, puckery, flat,
Digestion-promoting spleen-invigorating restrains stopping leak, for treating having indigestion abdominal distension, dysentery, enteritis, vitamin C deficiency etc..
Wintercherry（Physali alkekengiL.）Also known as groundcherry, franchet groundcherry persistent calyx or fruit, cape gooseberry etc..Containing more in Fruit of Physalis
Kind of nutritional ingredient, wherein the content of calcium be 73.1 times of tomato, 13.8 times of carrot, ascorbic content is tomato
6.4 times, 5.4 times of carrot.With unique flavor and nutrition abundant.Fruit of Physalis aromatic flavour, delicious.Berry is rich
Containing vitamin C, beta carotene, more than 20 kinds of mineral elements and 18 kinds of amino acid, there is heat-clearing, removing toxic substances, diuresis effect is usually used in
Control heat-syndrome cough, pharyngalgia, jaundice, dysentery, in water, the treatment of furunculosis, erysipelas etc..
Blackcurrant scientific name elements of black currant（Ribes nigrum L.）Also known as currant, purple plum etc., ripening fruits are black
Small berries, it is interior to be rich in vitamin C, anthocyanidin.Blackcurrant is not only a kind of delicious flavour, fruit full of nutrition, and has
Good medicinal efficacy.Blackcurrant fruit is rich in mineral matter element, and the Zn content in mineral matter element is high, can be used as and comes for zinc
Source；Ascorbic content is high, hence it is evident that is higher than citrus, hawthorn, also contains phosphorus, magnesium, potassium, calcium, anthocyanidin, phenolic substances.Seed
Linoleic acid content is high.Ascorbic content is very rich in blackcurrant, it is often more important that is also melted into containing a large amount of antioxygen
Point, this assures ascorbic function and effect.Blackcurrant is rich in such as anthocyanidin, vitamin C, flavones, Quercetin, red bayberry
The substances such as alcohol, phenolic acid, catechin and blackcurrant polysaccharide, these are all the bioactive substances with good anti-oxidation function.
Cactus（Scientific name：Opuntia stricta(Haw.)Haw.var.dillenii(Ker-Gawl.) Benson）,
It is a kind of plant of Opuntia.Alias celestial being palm, kwan-yin palm etc..Cactus is the meat shrub that grows thickly, the wide ovum of top branch
Shape, obovate elliptic or subcircular；Flower spoke shape, holder obovate.It is used as medicine with complete stool.The four seasons can adopt.
Cactus is cool in nature, sour, nontoxic.Have the promoting flow of qi and blood circulation, heat-clearing toxin-expelling functions.Mainly have clearing heat and detoxicating, eliminating stasis to subdue swelling,
The functions such as the promoting flow of qi and blood circulation, benefiting stomach and stopping pain.Cactus contains amino acid and various trace elements in needed by human 8, and embraces green
The preciousness ingredient such as lotus, Kok Beattie cents, cholla stem, starches through cactus crude drug and analyzes, contain pectin, polysaccharide and glue exudate.From herb point
From extracting to obtain freidelin ketone（friedelin）, -3 α -ol of freidelin（friedelan-3-α-ol）, taraxerone
（taraxerone）And taraxerol（taraxerol）.
Eggshell, quantity is biggish in China's poultry farming chicken, duck, goose and quail etc., using egg, duck's egg,
As in food processing process, the useless eggshell enormous amount generated is provided according to existing disclosed report for goose egg and quail egg
Material display, the eggshell total amount that a medium-sized city is monthly discarded reach 60-100 tons, and account for egg size by Eggshell weight 11% calculates,
The eggshell that about 1,500,000 tons of the daily output in China, not only pollutes environment, but also waste of resource in this way.Discarded eggshell is integrated
It utilizes, resource utilization can not only be improved and avoids environmental pollution, and be greatly improved the economic benefit and social benefit of enterprise.
Wherein egg shell is in China's yield maximum, and egg shell accounts for the 10-12% in entire egg, by under film, shell on shell
Film and eggshell three parts composition, eggshell is a kind of calcareous hard shell, is located on shell between film and shell lower film.In the change of egg shell
In studying point, minerals account for 95%, and protein 3.3%, moisture 1%, fat 0.03%, remaining is carbohydrate and other have
Machine substance（It certainly, does not include a large amount of remaining egg white in eggshell in the above ingredient）.Eggshell mineral ingredient is mainly
Calcium carbonate accounts for 94% or so, remaining is magnesium carbonate and calcium phosphate, and calcium, phosphorus content account for 34.9% and of eggshell dry matter respectively
0.2%.In eggshell, seven kinds of vitamins and various trace elements and some important enzymes, peptide matters can be measured, he
Although content seldom, be all the substance needed in human body or animal body.
In the prior art, it is replenished the calcium with egg-shell meal, has the product of the grinds after sterilizing by eggshell in people's product, also have
The application of organic calcium is prepared into using primary or secondary clacining method.It is at present most widely in drug, food and nutriment
In preparation, micron order, submicron order and nano level superfine powder are mostly used, is added to various food, nutrition kind, has reached very
Good effect.Application of the eggshell in China's animal-breeding is taken mostly by eggshell cleaning, drying, and milling is added into feed
The method of feeding, since grinding particle size is larger, being absorbed and utilized for animal is poor, can't reach good application effect.
The present invention is to clean eggshell, after high temperature drying, then be made one through spice, charing, activation, cleaning, drying, screening
The adsorbent of kind function admirable, the program not only remains the nutrition that eggshell utilizes, while making the abundant carbonaceous of eggshell, not only right
It is contained it is calcareous form organic calcium, and form the filling substrate with adsorption capacity.
The beneficial effects of the invention are as follows：
（1）Product of the present invention is single type bifidobacterium longum additive, can have to producer's offer and targetedly select
With use, product can highlight the viable bacteria content of bifidobacterium longum.Survival rate of the thallus in closed composite packaging is significantly improved,
Through batches of products reserved sample observing 12 months at room temperature, bifidobacterium longum average viability is 90.4%, and reference substance（It is right
Filler according to product is wheat bran）In bifidobacterium longum survival rate be 63.7%；
（2）Pass through sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder and long bifid
Bacillus mixes, and due to the stickum in the colloidal substance that these dry powder formulations are rich in, especially cactus, can preferably increase
Adhesive effect between additive and feed, and improve the utilization rate of additive；
（3）By sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus freeze-dried powder high-content amino acid, vitamin, mineral element, more
Sugar.The nutritional ingredients such as the vitamin C of organic acid, especially high-content and various bioactivators, to raising animal immune energy
Power is simultaneously obviously improved meat, Egg Quality, the acidic materials in especially above-mentioned dry powder, utilization, promotion animal to contained microorganism
Digestion all has significant effect；
（4）Due to using Freeze Drying Technique means, enable sea-buckthorn obtained, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus freeze-dried powder
Its active constituent is maximumlly remained, has distinctive sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, the smell of cactus application and taste
Taste, free from extraneous odour add the preference of animal.
（5）Eggshell is first subjected to drying and other treatment through high temperature using charing egg-shell meal, further through spice, charing, activation, clear
It washes, dry and sieves, form a kind of excellent adsorbent, which not only forms absorption to the saccharomycete in product
Power, while making the eggshell after charing that still there is the organic calcium effect of activation, meanwhile, after animal feeding, have well to stomach
The toxin of enteron aisle has suction-operated, has stop dysentery, antidiarrheal effect for the animal of diarrhea and diarrhea, has good active carbon
Medicinal effects.
（6）To the preparation of sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus freeze-dried powder in the present invention, do not remove the peel, deseeding step
Suddenly, it is therefore an objective to by being crushed after freeze-drying, so that its skin and seed is worn into fine powder, make anthocyanidin, oil in its skin and seed
Class, organic acid, bud fragrance substance are retained, and the nutritive value of its freeze-dried powder is promoted.
（7）The present invention is lyophilized using sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus
Powder, matrix of the charing egg-shell meal as additive contain constants such as a large amount of calcium, phosphorus, potassium, sodium, magnesium, zinc and micro in matrix
Element, vitamin C still rich in, anthocyanidin, beta carotene, malic acid, citric acid, protein, amino acid, nucleic acid, Portugal
Grape sugar, lipoidis, carbohydrate, B family vitamin such as B1、B2、B6、B12And the physiological activity such as folic acid, niacin, pantothenic acid, inositol
Substance, not only improves the nutritive value of bifidobacterium longum additive, while promoting the metabolism of animal, improves the disease-resistant of body
Ability promotes growth of animal, finally improves the economic benefit of its aquaculture.
（8）Product of the present invention uses interior outer bag composite packaging, and interior outer bag interlayer is filled with silica-gel desiccant, and product does not return
Tide, no agglomeration, product is loose, good fluidity, can preferably keep exterior quality and inherent quality.
Operation to not having its technical process stated in detail in the present invention is in the common sense of those skilled in the art
Operation.With regard to the purchase and storage of heretofore described sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant fresh fruit and fresh cactus, the present invention
The construction of people's unit has 20,000 tons of freezer facility, has enough guarantees to storage fresh fruit material.
Specific embodiment
Embodiment 1
The preparation of sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder：
Sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, the cactus for taking fresh mature respectively remove carpopodium, the impurity such as rotten fruit, with containing heavy
40 DEG C of aqueous solutions of 0.1% citric acid are measured, 15min is rinsed under constant stirring and pulls out, be put into pure water and rinse 3 times, pull out
It is drained；It will be moved into refrigerator after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively, be cooled to -45 DEG C rapidly
Below；Respectively by the sea-buckthorn freezed, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus move into lyophilization machine in, sublimation temperature control-
22--32 DEG C, vacuum degree 120-150Pa makes dry materials to moisture < 6%（w）, the time about needs 18 hours, is put into after taking-up
In freezing crusher, control temperature of charge is no more than 0 DEG C, after being crushed to 100 mesh of fineness >, respectively obtains sea-buckthorn freeze-dried powder, thorn
Pears freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder, are fitted into polybag and seal, and are stored in 0 DEG C or less
It is spare in freezer.
Embodiment 2
Carbonize the preparation of egg-shell meal：
Eggshell is cleaned up first, dries moisture, is placed in electric baking case, the heated-air drying 2 hours under the conditions of 200 DEG C,
After taking-up is let cool, 20 mesh coarse powder are pulverized into, by weight 1:0.5 sprays prepared weight ratio on eggshell coarse powder for 25%
Salt solution（That is egg-shell meal：25% salt solution=1:0.5 ratio）, mixed in sprinkling, place 6 hours after mixing, then
Uniformly mixing is primary again, then places 6 hours；Impregnated eggshell powder raw material is put into rotary carbonizing pot, in 420 DEG C of backspins
Turn charing 80 minutes, until observing the complete blackening of raw material（Carbonization process prevents charcoal in being equipped with the scraping blade rotated automatically in charing pot
Raw material glues pot and agglomeration during change）；The raw material carbonized is rapidly moved in activation furnace, CO is passed through2Gas is caught up with therein to the greatest extent
Air, anoxybiotic activates 80 minutes at 760 DEG C（Controllable stirring is set in activation furnace and stirs blade, is made every in activation raw material
It is stirred within 10 minutes once, guarantees activation material fully and uniformly）；After activation, activated material is taken out, is allowed to cool normal
Temperature gradually rinses activated material in rinse bath with clear water, until basic inspection does not measure sodium chloride, has cleaned sodium chloride
Afterwards, it is submerged activated material 2.5 hours with the hydrochloric acid of mass ratio 12%, is finished wait impregnate, with 95 DEG C of pure water washing activated materials, until
Expect that grain filters 7.0 there is no after white, then with room temperature pure water rinse to pH value, obtains rinse activator material；By rinsed clean
Activated material, which is dried at 115 DEG C to water content, is lower than 6%, crosses 60 meshes, and the coarse grain after screening is pulverized again, makes all to pass through
60 meshes are to get charing egg-shell meal product.
Embodiment 3
Carbonize the preparation of egg-shell meal：
Eggshell is cleaned up first, dries moisture, is placed in far-infrared dryer, it is 1 hour dry under the conditions of 300 DEG C, it takes
After letting cool out, 30 mesh coarse powder are pulverized into, by weight 1:0.5 sprays the food that prepared weight ratio is 25% on eggshell coarse powder
Salting liquid（That is egg-shell meal：25% salt solution=1:0.5 ratio）, mixed in sprinkling, place 7 hours after mixing, then again
Uniformly mixing is primary, then places 7 hours；Impregnated eggshell powder raw material is put into rotary carbonizing pot, is rotated at 450 DEG C
Charing 70 minutes, until observing the complete blackening of raw material（Carbonization process prevents from carbonizing in being equipped with the scraping blade rotated automatically in charing pot
Raw material glues pot and agglomeration in the process）；The raw material carbonized is rapidly moved in activation furnace, CO is passed through2Gas catches up with sky therein to the greatest extent
Gas, anoxybiotic activates 55 minutes at 800 DEG C（Controllable stirring is set in activation furnace and stirs blade, is made in activation raw material every 10
Minute is stirred once, guarantees activation material fully and uniformly）；After activation, activated material is taken out, is allowed to cool normal
Temperature gradually rinses activated material in rinse bath with clear water, until basic inspection does not measure sodium chloride, has cleaned sodium chloride
Afterwards, it is submerged activated material 3 hours with the hydrochloric acid of mass ratio 12%, is finished wait impregnate, with 95 DEG C of pure water washing activated materials, until material
Grain filters 7.0 there is no after white, then with room temperature pure water rinse to pH value, obtains rinse activator material；By the work of rinsed clean
Material, which is dried at 120 DEG C to water content, is lower than 6%, crosses 60 meshes, the coarse grain after screening is pulverized again, made all by 60
Mesh is to get charing egg-shell meal product.
Embodiment 4
A kind of bifidobacterium longum feed addictive is frozen by bifidobacterium longum dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry
Dry powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed, compound packet
Dress is made：The bifidobacterium longum 10000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 5g, Rosa roxburghii freeze-dried powder 50g, acid
Freeze-dried powder 3g, blackcurrant freeze-dried powder 3g, cactus freeze-dried powder 150g are starched, remaining is charing egg-shell meal；Specific production method is to claim
The difference of Example 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder
It mixes, then bifidobacterium longum dry powder is uniformly admixed, then addition surplus carbonizes egg-shell meal as made from embodiment 2 and is sufficiently mixed
After uniformly, composite packaging is carried out；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag uses aluminium foil bag, between interior outer bag
Add a few packet silica-gel desiccants, to prevent water suction.
Embodiment 5
A kind of bifidobacterium longum feed addictive is frozen by bifidobacterium longum dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry
Dry powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed, compound packet
Dress is made：The bifidobacterium longum 30000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 45g, Rosa roxburghii freeze-dried powder 8g, acid
Freeze-dried powder 5g, blackcurrant freeze-dried powder 5g, cactus freeze-dried powder 145g are starched, remaining is charing egg-shell meal；Specific production method is to claim
The difference of Example 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder
It mixes, then bifidobacterium longum dry powder is uniformly admixed, then addition surplus carbonizes egg-shell meal as made from embodiment 2 and is sufficiently mixed
After uniformly, composite packaging is carried out；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag uses aluminium foil bag, between interior outer bag
Add a few packet silica-gel desiccants, to prevent water suction.
Embodiment 6
A kind of bifidobacterium longum feed addictive is frozen by bifidobacterium longum dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry
Dry powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed, compound packet
Dress is made：The bifidobacterium longum 50000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 45g, Rosa roxburghii freeze-dried powder 15g,
Wintercherry freeze-dried powder 10g, blackcurrant freeze-dried powder 10g, cactus freeze-dried powder 90g, remaining is charing egg-shell meal；Specific production method
It is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus respectively
Freeze-dried powder mixes, then bifidobacterium longum dry powder is uniformly admixed, and then addition surplus carbonizes egg-shell meal as made from embodiment 2 and fills
Divide after mixing, carries out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag uses aluminium foil bag, inside and outside
Add a few packet silica-gel desiccants between bag, to prevent water suction.
Embodiment 7
A kind of bifidobacterium longum feed addictive is frozen by bifidobacterium longum dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry
Dry powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed, compound packet
Dress is made：The bifidobacterium longum 80000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 25g, Rosa roxburghii freeze-dried powder 15g,
Wintercherry freeze-dried powder 15g, blackcurrant freeze-dried powder 12g, cactus freeze-dried powder 100g, remaining is charing egg-shell meal；Specific production method
It is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus respectively
Freeze-dried powder mixes, then bifidobacterium longum dry powder is uniformly admixed, and then addition surplus carbonizes egg-shell meal as made from embodiment 2 and fills
Divide after mixing, carries out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag uses aluminium foil bag, inside and outside
Add a few packet silica-gel desiccants between bag, to prevent water suction.
Embodiment 8
A kind of bifidobacterium longum feed addictive is frozen by bifidobacterium longum dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry
Dry powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed, compound packet
Dress is made：The bifidobacterium longum 85000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 10g, Rosa roxburghii freeze-dried powder 30g,
Wintercherry freeze-dried powder 20g, blackcurrant freeze-dried powder 15g, cactus freeze-dried powder 110g, remaining is charing egg-shell meal；Specific production method
It is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus respectively
Freeze-dried powder mixes, then bifidobacterium longum dry powder is uniformly admixed, and then addition surplus carbonizes egg-shell meal as made from embodiment 2 and fills
Divide after mixing, carries out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag uses aluminium foil bag, inside and outside
Add a few packet silica-gel desiccants between bag, to prevent water suction.
Embodiment 9
A kind of bifidobacterium longum feed addictive is frozen by bifidobacterium longum dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry
Dry powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed, compound packet
Dress is made：The bifidobacterium longum 90000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 25g, Rosa roxburghii freeze-dried powder 50g,
Wintercherry freeze-dried powder 20g, blackcurrant freeze-dried powder 20g, cactus freeze-dried powder 120g, remaining is charing egg-shell meal；Specific production method
It is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus respectively
Freeze-dried powder mixes, then bifidobacterium longum dry powder is uniformly admixed, and then addition surplus carbonizes egg-shell meal as made from embodiment 3 and fills
Divide after mixing, carries out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag uses aluminium foil bag, inside and outside
Add a few packet silica-gel desiccants between bag, to prevent water suction.
Embodiment 10
A kind of bifidobacterium longum feed addictive is frozen by bifidobacterium longum dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry
Dry powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed, compound packet
Dress is made：The bifidobacterium longum 100000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 50g, Rosa roxburghii freeze-dried powder 30g,
Wintercherry freeze-dried powder 30g, blackcurrant freeze-dried powder 30g, cactus freeze-dried powder 115g, remaining is charing egg-shell meal；Specific production method
It is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus respectively
Freeze-dried powder mixes, then bifidobacterium longum dry powder is uniformly admixed, and then addition surplus carbonizes egg-shell meal as made from embodiment 3 and fills
Divide after mixing, carries out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag uses aluminium foil bag, inside and outside
Add a few packet silica-gel desiccants between bag, to prevent water suction.
Embodiment 11
A kind of bifidobacterium longum feed addictive is frozen by bifidobacterium longum dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry
Dry powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed, compound packet
Dress is made：The bifidobacterium longum 110000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 50g, Rosa roxburghii freeze-dried powder 40g,
Wintercherry freeze-dried powder 20g, blackcurrant freeze-dried powder 20g, cactus freeze-dried powder 125g, remaining is charing egg-shell meal；Specific production method
It is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus respectively
Freeze-dried powder mixes, then bifidobacterium longum dry powder is uniformly admixed, and then addition surplus carbonizes egg-shell meal as made from embodiment 3 and fills
Divide after mixing, carries out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag uses aluminium foil bag, inside and outside
Add a few packet silica-gel desiccants between bag, to prevent water suction.
Embodiment 12
A kind of bifidobacterium longum feed addictive is frozen by bifidobacterium longum dry powder, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry
Dry powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed, compound packet
Dress is made：The bifidobacterium longum 120000 hundred million in every 1000g feed addictive, sea-buckthorn freeze-dried powder 50g, Rosa roxburghii freeze-dried powder 50g,
Wintercherry freeze-dried powder 25g, blackcurrant freeze-dried powder 25g, cactus freeze-dried powder 50g, remaining is charing egg-shell meal；Specific production method
It is to weigh embodiment 1 sea-buckthorn freeze-dried powder obtained, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus respectively
Freeze-dried powder mixes, then bifidobacterium longum dry powder is uniformly admixed, and then addition surplus carbonizes egg-shell meal as made from embodiment 3 and fills
Divide after mixing, carries out composite packaging；Composite packaging is inner bag using polypropylene plastics pocket, and outer bag uses aluminium foil bag, inside and outside
Add a few packet silica-gel desiccants between bag, to prevent water suction.
Claims (9)
1. bifidobacterium longum feed addictive, feature it be first by bifidobacterium longum, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder,
Wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed,
Composite packaging is made：Bifidobacterium longum 10000 hundred million -120000 hundred million, sea-buckthorn freeze-dried powder 5- in every 1000g feed addictive
50g, Rosa roxburghii freeze-dried powder 5-50g, wintercherry freeze-dried powder 3-30g, blackcurrant freeze-dried powder 3-30g, cactus freeze-dried powder 50-150g,
Remaining is charing egg-shell meal；The sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-drying
Powder is made by following methods, and technical process is that fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus is taken to remove fruit respectively
Stalk, the impurity such as rotten fruit, rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；Rinsing item described above
Part is to rinse 15min, and be stirred continuously with the citric acid of 40 DEG C of water addition weight 0.1%, pulls out to be put into pure water and rinses 3
It is secondary；Above-mentioned freezing is will to be cooled to rapidly -45 DEG C or less after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively；It is above-mentioned
The process conditions of lyophilization are temperature-22-- 32 DEG C, and vacuum degree 120-150Pa is dry until moisture is less than 6%/w；
The charing egg-shell meal is made by following methods：（1）Dry, dipping first cleans up eggshell, dries moisture, first
Row is dried 1-2 hours, then pulverizes into 20-30 mesh coarse powder, by weight 1:0.5 sprayed on eggshell coarse powder it is prepared
The salt that weight fraction is 25%（Sodium chloride）Solution is mixed in sprinkling, is placed after mixing 6-7 hours, then uniformly mixed again
Unification time, then place 6-7 hours；The purpose is to allow salt effectively to penetrate into eggshell organization internal gap；（2）Charing will
Impregnated eggshell powder raw material is put into rotary carbonizing pot, is carbonized 70-80 minutes, is seen in 420-450 DEG C of at a temperature of rotation
Until examining the complete blackening of raw material；（3）The raw material carbonized is rapidly moved in activation furnace by activation, is closed fire door, is passed through titanium dioxide
Carbon gas catches up with air therein to the greatest extent, and anoxybiotic activates 55-85 minutes at 720-800 DEG C；（4）After activated material is taken out in cleaning, allow
It is cooled to room temperature, activated material is gradually rinsed in rinse bath with clear water, until not measuring sodium chloride until examining substantially；Cleaning
After complete sodium chloride, submerged activated material 2.5-3 hours with the hydrochloric acid that mass ratio is 12%, after impregnating, with 95 DEG C of pure water
Activated material is washed, until material grain is there is no after white, then room temperature pure water rinse to neutrality is used, filters, obtain rinse activator material；
（5）Dry and screening, which dries the activated material of rinsed clean at 115-120 DEG C to water content, is lower than 6%/w, crosses 60 meshes,
Coarse grain after screening is pulverized again, make all by 60 meshes to get.
2. bifidobacterium longum feed addictive, feature it be first by bifidobacterium longum, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder,
Wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed,
Composite packaging is made：Bifidobacterium longum 30000 hundred million -120000 hundred million, sea-buckthorn freeze-dried powder in every 1000g feed addictive
10-50g, Rosa roxburghii freeze-dried powder 8-50g, wintercherry freeze-dried powder 5-30g, blackcurrant freeze-dried powder 5-30g, cactus freeze-dried powder 70-150g,
Remaining is charing egg-shell meal；The sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus are frozen
Dry powder is made by following methods, and technical process is that fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus is taken to remove respectively
Carpopodium, the impurity such as rotten fruit, rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；Rinsing described above
Condition is to rinse 15min, and be stirred continuously with the citric acid of 40 DEG C of water addition weight 0.1%, pulls out to be put into pure water and rinses
3 times；Above-mentioned freezing is will to be cooled to rapidly -45 DEG C or less after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively；On
The process conditions for stating lyophilization are temperature-22-- 32 DEG C, and vacuum degree 120-150Pa is dry to be less than 6%/w to moisture
Only；The charing egg-shell meal is made by following methods：（1）Dry, dipping first cleans up eggshell, dries moisture,
It is dried 1-2 hours in advance, then pulverizes into 20-30 mesh coarse powder, by weight 1:0.5 sprays on eggshell coarse powder and prepares
Weight fraction be 25% salt（Sodium chloride）Solution is mixed in sprinkling, is placed after mixing 6-7 hours, then uniform again
Mixing is primary, then places 6-7 hours；The purpose is to allow salt effectively to penetrate into eggshell organization internal gap；（2）Charing
Impregnated eggshell powder raw material is put into rotary carbonizing pot, is carbonized 70-80 minutes in 420-450 DEG C of at a temperature of rotation,
Until observing the complete blackening of raw material；（3）The raw material carbonized is rapidly moved in activation furnace by activation, is closed fire door, is passed through dioxy
Change carbon gas, catch up with air therein to the greatest extent, anoxybiotic activates 55-85 minutes at 720-800 DEG C；（4）After activated material is taken out in cleaning,
It is allowed to cool room temperature, activated material is gradually rinsed in rinse bath with clear water, until not measuring sodium chloride until examining substantially；Clearly
After washing sodium chloride, submerged activated material 2.5-3 hours with the hydrochloric acid that mass ratio is 12%, it is pure with 95 DEG C after impregnating
Water washing activated material until material grain is there is no after white, then uses room temperature pure water rinse to neutrality, filters, obtain rinse activator material；
（5）Dry and screening, which dries the activated material of rinsed clean at 115-120 DEG C to water content, is lower than 6%/w, crosses 60 meshes,
Coarse grain after screening is pulverized again, make all by 60 meshes to get.
3. bifidobacterium longum feed addictive, feature it be first by bifidobacterium longum, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder,
Wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed,
Composite packaging is made：Bifidobacterium longum 50000 hundred million -120000 hundred million, sea-buckthorn freeze-dried powder in every 1000g feed addictive
15-50g, Rosa roxburghii freeze-dried powder 12-50g, wintercherry freeze-dried powder 8-30g, blackcurrant freeze-dried powder 8-30g, cactus freeze-dried powder 85-
150g, remaining is charing egg-shell meal；The sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, celestial being
People slaps freeze-dried powder, is made by following methods, and technical process is to take fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, celestial being respectively
The palm removes carpopodium, the impurity such as rotten fruit, and rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；It is described above
Rinsing condition be to be rinsed 15min, and be stirred continuously, pulled out and be put into pure water with the citric acid of 40 DEG C of water addition weight 0.1%
Middle rinsing 3 times；Above-mentioned freezing be will be cooled to rapidly after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively -45 DEG C with
Under；The process conditions of above-mentioned lyophilization are temperature-22-- 32 DEG C, vacuum degree 120-150Pa, it is dry to moisture less than 6%/
Until w；The charing egg-shell meal is made by following methods：（1）Dry, dipping first cleans up eggshell, dries water
Point, it is dried 1-2 hours in advance, then pulverizes into 20-30 mesh coarse powder, by weight 1:0.5 sprays on eggshell coarse powder and matches
The salt that the weight fraction made is 25%（Sodium chloride）Solution mixes in sprinkling, places 6-7 hours after mixing, then again
Uniformly mixing is primary, then places 6-7 hours；The purpose is to allow salt effectively to penetrate into eggshell organization internal gap；（2）Charcoal
Impregnated eggshell powder raw material is put into rotary carbonizing pot by change, carbonizes 70-80 points in 420-450 DEG C of at a temperature of rotation
Clock, until observing the complete blackening of raw material；（3）The raw material carbonized is rapidly moved in activation furnace by activation, is closed fire door, is passed through
Carbon dioxide gas catches up with air therein to the greatest extent, and anoxybiotic activates 55-85 minutes at 720-800 DEG C；（4）Activated material is taken out in cleaning
Afterwards, it is allowed to cool room temperature, activated material is gradually rinsed in rinse bath with clear water, sodium chloride is not measured until examining substantially and is
Only；After having cleaned sodium chloride, submerged activated material 2.5-3 hours with the hydrochloric acid that mass ratio is 12%, after impregnating, with 95 DEG C
Pure water washing activated material until material grain is there is no after white, then uses room temperature pure water rinse to neutrality, filters, must rinse work
Material；（5）Dry and screening, which dries the activated material of rinsed clean at 115-120 DEG C to water content, is lower than 6%/w, crosses 60
Mesh, the coarse grain after screening are pulverized again, make all by 60 meshes to get.
4. bifidobacterium longum feed addictive, feature it be first by bifidobacterium longum, sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder,
Wintercherry freeze-dried powder, blackcurrant freeze-dried powder, cactus freeze-dried powder be uniformly mixed, then add surplus charing egg-shell meal be uniformly mixed,
Composite packaging is made：Bifidobacterium longum 80000 hundred million -120000 hundred million, sea-buckthorn freeze-dried powder in every 1000g feed addictive
20-50g, Rosa roxburghii freeze-dried powder 15-50g, wintercherry freeze-dried powder 10-30g, blackcurrant freeze-dried powder 10-30g, cactus freeze-dried powder 100-
150g, remaining is charing egg-shell meal；The sea-buckthorn freeze-dried powder, Rosa roxburghii freeze-dried powder, wintercherry freeze-dried powder, blackcurrant freeze-dried powder, celestial being
People slaps freeze-dried powder, is made by following methods, and technical process is to take fresh sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, celestial being respectively
The palm removes carpopodium, the impurity such as rotten fruit, and rinsing, freezing, lyophilization, low-temperature grinding are not removed the peel, deseeding step；It is described above
Rinsing condition be to be rinsed 15min, and be stirred continuously, pulled out and be put into pure water with the citric acid of 40 DEG C of water addition weight 0.1%
Middle rinsing 3 times；Above-mentioned freezing be will be cooled to rapidly after sea-buckthorn, Rosa roxburghii Tratt, wintercherry, blackcurrant, cactus sabot respectively -45 DEG C with
Under；The process conditions of above-mentioned lyophilization are temperature-22-- 32 DEG C, vacuum degree 120-150Pa, it is dry to moisture less than 6%/
Until w；The charing egg-shell meal is made by following methods：（1）Dry, dipping first cleans up eggshell, dries water
Point, it is dried 1-2 hours in advance, then pulverizes into 20-30 mesh coarse powder, by weight 1:0.5 sprays on eggshell coarse powder and matches
The salt that the weight fraction made is 25%（Sodium chloride）Solution mixes in sprinkling, places 6-7 hours after mixing, then again
Uniformly mixing is primary, then places 6-7 hours；The purpose is to allow salt effectively to penetrate into eggshell organization internal gap；（2）Charcoal
Impregnated eggshell powder raw material is put into rotary carbonizing pot by change, carbonizes 70-80 points in 420-450 DEG C of at a temperature of rotation
Clock, until observing the complete blackening of raw material；（3）The raw material carbonized is rapidly moved in activation furnace by activation, is closed fire door, is passed through
Carbon dioxide gas catches up with air therein to the greatest extent, and anoxybiotic activates 55-85 minutes at 720-800 DEG C；（4）Activated material is taken out in cleaning
Afterwards, it is allowed to cool room temperature, activated material is gradually rinsed in rinse bath with clear water, sodium chloride is not measured until examining substantially and is
Only；After having cleaned sodium chloride, submerged activated material 2.5-3 hours with the hydrochloric acid that mass ratio is 12%, after impregnating, with 95 DEG C
Pure water washing activated material until material grain is there is no after white, then uses room temperature pure water rinse to neutrality, filters, must rinse work
Material；（5）Dry and screening, which dries the activated material of rinsed clean at 115-120 DEG C to water content, is lower than 6%/w, crosses 60
Mesh, the coarse grain after screening are pulverized again, make all by 60 meshes to get.
5. the bifidobacterium longum feed addictive as described in claim 1-4, which is characterized in that the bifidobacterium longum is
Every gram is no less than 200 hundred million thalli dry powder products containing viable bacteria concentration.
6. the bifidobacterium longum feed addictive as described in claim 1-4, which is characterized in that the low-temperature grinding is material
Temperature is in 0 DEG C or less and is crushed.
7. the bifidobacterium longum feed addictive as described in claim 1-4, which is characterized in that in the composite packaging uses
Outer bag composite packaging, inner bag use polypropylene plastics pocket, and outer packing uses aluminium foil bag, is filled with silica-gel desiccant between interior outer bag
Pouch.
8. the bifidobacterium longum feed addictive as described in claim 1-4, which is characterized in that the eggshell be egg shell,
Any one or a few mixing eggshell in Ovum Anas domestica putamina, goose egg-shell and quail eggshell.
9. the bifidobacterium longum feed addictive as described in claim 1-4, which is characterized in that the drying uses hot air drying
Dry or far-infrared ray drying；The drying condition is 180 DEG C -300 DEG C.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810511925.0A CN108850482A (en) | 2018-05-25 | 2018-05-25 | Bifidobacterium longum feed addictive |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810511925.0A CN108850482A (en) | 2018-05-25 | 2018-05-25 | Bifidobacterium longum feed addictive |
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| Publication Number | Publication Date |
|---|---|
| CN108850482A true CN108850482A (en) | 2018-11-23 |
Family
ID=64333692
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810511925.0A Withdrawn CN108850482A (en) | 2018-05-25 | 2018-05-25 | Bifidobacterium longum feed addictive |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN108850482A (en) |
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2018
- 2018-05-25 CN CN201810511925.0A patent/CN108850482A/en not_active Withdrawn
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