CN108849914A - Agricultural chemical composition for disinsection and its preparation method and application - Google Patents
Agricultural chemical composition for disinsection and its preparation method and application Download PDFInfo
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- CN108849914A CN108849914A CN201811000002.5A CN201811000002A CN108849914A CN 108849914 A CN108849914 A CN 108849914A CN 201811000002 A CN201811000002 A CN 201811000002A CN 108849914 A CN108849914 A CN 108849914A
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- Prior art keywords
- mibemycin
- agent
- nitrile pyrrole
- mite ester
- pyrrole mite
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Classifications
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/56—1,2-Diazoles; Hydrogenated 1,2-diazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
Abstract
The invention discloses a kind of agricultural chemical composition for disinsection and its preparation method and application.The present invention has found that mibemycin and nitrile pyrrole mite ester mixture have synergistic killing effect to red spider by a large amount of formula indoor screening test, and field test results also indicate that the effect of mibemycin and nitrile pyrrole mite mixture preparation is better than the use of single dose；The present invention provides a kind of agricultural chemical composition for disinsection as a result, and the composition pesticide is using mibemycin and nitrile pyrrole mite ester as active constituent；Acceptable auxiliary material on pesticidal preparations will be added in active constituent, various pesticidal preparations can be prepared into.For the present invention by after mibemycin and nitrile pyrrole mite ester mixture, the two has significant synergistic function, improves control efficiency and extends the medicament lasting period, reduces drug cost；It can prevent mite class from developing drug resistance, extend the service life of pesticide species；Good to crop safety, quick-acting is good, and the lasting period is long, and application cost is low, meets the security requirement of pesticidal preparations.
Description
Technical field
The present invention relates to agricultural chemical composition for disinsection, more particularly to are made of mibemycin and nitrile pyrrole mite ester for active constituent
Agricultural chemical composition for disinsection and preparation method thereof, the invention further relates to the various pesticidal preparations of composition pesticide preparation and
It is killing the application in agriculture and forestry injurious insect, belongs to agricultural chemical composition for disinsection field.
Background technique
With the increasingly raising that people require environment, agricultural product security, the upgrading of Pesticidal products is also gradually accelerated,
Domestic some kinds of acaricide earlier are because safety issue has been prohibited from using, and safety is relatively high kills agent of walking haltingly also because of length
Phase uses, and resistance problem also has different degrees of show.
Mibemycin is the 16-membered ring macrolides antibiotic by extracting in the certain bacterial strain fermentation liquors of streptomyces,
There is wide spectrum, height as a kind of new biological pesticide with strong desinsection, mite killing, expelling parasite and the biological activities such as antitumor
The advantages that imitating, be environmental-friendly, to safety of human and livestock.It and avermectin are known as the current highest insecticide of activity together, are mesh
Preceding one of the biological pesticide for most having application prospect.
Nitrile pyrrole mite ester is the novel propylene nitrile acaricide developed by Japanese Nissan chemical industry Co., Ltd., the mechanism of action
It is mainly related with the activating metabolism of deesterify enol, pass through complexⅱ (the succinic acid dehydrogenation destroyed in respiratory electron transport chain
Enzyme) inhibit the function of mitochondria, the insecticidal/acaricidal agent and existing mainstream insecticide no interactions resistance.Nitrile pyrrole mite ester has low
The features such as malicious, low dosage and mite killing spectrum are wide, to mandarin tree, apple tree, pear tree, grape, strawberry, capsicum, watermelon, tea tree, rose
All kinds of harmful mites, red spider, heart-eating worm on equal crops etc. all have good prevention and treatment activity.
Mite class easily generates resistance, is compounded with the ingredient of different role mechanism, and pest and disease damage drug resistance can be effectively delayed
Generation, be slow down drug resistance generation common and effective method.It develops, popularization and use are efficient, environmental protection, have synergistic effect
Compound preparation helps to prevent and harmful mite is overcome to develop drug resistance, facilitates environmental protection.
Summary of the invention
An object of the present invention, which is to provide one kind, can effectively delay pest and disease damage drug resistance to generate, the high desinsection of insecticidal activity
Composition pesticide；
The second object of the present invention is to the agricultural chemical composition for disinsection is prepared into various conventional pesticidal preparations；
The third object of the present invention is to be applied to the composition pesticide to kill the various pests of agriculture and forestry, especially mite
Worm.
Above-mentioned purpose of the invention is achieved through the following technical solutions：
The present inventor has found mibemycin and nitrile pyrrole mite ester mixture to red spider by a large amount of formula indoor screening test
Spider has synergistic killing effect, and field test results also indicate that the effect of mibemycin and nitrile pyrrole mite mixture preparation is excellent
In the use of single dose；Therefore, present invention firstly provides a kind of agricultural chemical composition for disinsection, and the composition pesticide is with mibemycin
It is main active with nitrile pyrrole mite ester.
The present invention is by further experiment discovery, the effect of the ratio of nitrile pyrrole mite ester and mibemycin for desinsection
Fruit influences highly significant, wherein nitrile pyrrole mite ester and mibemycin are according to (1~49): the mass ratio of (1~49) is matched
5, compared to other proportions, preferable insecticidal effect can be obtained, further, nitrile pyrrole mite ester and mibemycin are according to (1
~9): the mass ratio of (1~49) carries out compatibility, and insecticidal effect more preferably, further, press by nitrile pyrrole mite ester and mibemycin
According to 1: the mass ratio of (9~49) carries out compatibility, and insecticidal effect is further improved；When nitrile pyrrole mite ester and mibemycin
According to 1:When 9 mass ratio carries out compatibility, the cooperative synergism effect of the two is the most significant, and the activity of desinsection has been reached most
It is high.
Acceptable auxiliary material or carrier in Pesticide Science are added on the basis of composition pesticide of the present invention, that is, can be prepared into various
Dosage form, such as suspending agent, wettable powder, water dispersible granules, microemulsion, aqueous emulsion, oil suspending agent dosage form.The formulations of pesticide
Preparation method is well known to those skilled in the art.
Auxiliary material or carrier of the present invention, such as emulsifier, wetting dispersing agent, thickener, antifreezing agent, stabilizer, anti-corrosion
Agent, disintegrating agent, binder etc. may each be component conventional in pesticide.For example, the emulsifier is selected from non-ionic surface active
Agent castor oil ethylene oxide adduct (EL40 or EL90), nonylphenol polyoxyethylene ether, fatty alcohol polyoxyethylene ether, phenethyl
One or more of phenol polyethenoxy polyethenoxy ether, APES formaldehyde condensation product.The wetting dispersing agent
Selected from lauryl sodium sulfate, Nekal BX, alkylphenol-polyethenoxy base ether, naphthalene sulfonic acid-formaldehyde condensation product salt or polyoxyethylene
The mixture that one or more of base polyoxypropylene ether block copolymers are formed according to arbitrary proportion.The thickener choosing
From one of xanthan gum, carboxymethyl cellulose, Sodium Polyacrylate, aluminum magnesium silicate, gaseous silicon oxide or attapulgite or several
Kind.The antifreezing agent is any in ethylene glycol, propylene glycol, glycerol, glycerol-ether diglycol or methyl propylene diglycol
The mixture that one or more are formed according to arbitrary proportion.The stabilizer is selected from 2,6- di-t-butyl -4- methylbenzene
Any one or more in phenol (BHT), citric acid or butylated hydroxy anisole (BHA).The disintegrating agent is selected from urea, swelling
Any one or more in soil, montmorillonite or sodium alginate.The binder is selected from gelatin, Arabic gum, xanthan gum, three
One of polyphosphate sodium, phenolic resin or polyvinylpyrrolidone are a variety of.The filler can be kaolin etc..
As reference, the present invention provides the methods that the composition pesticide is prepared into agricultural chemicals suspension agent, including：
By nitrile pyrrole mite ester, mibemycin and wetting agent, dispersing agent, antifreeze, preservative, the thickener (70- of gross mass
50%), the uniformly mixed grinding such as defoaming agent (70-50% of gross mass) and water stops grinding, adds when partial size is at 5 μm
Remaining thickener and defoaming agent obtain suspending agent after adjusting uniformly.
As reference, the present invention provides the methods that the composition pesticide is prepared into microemulsion, including：
Nitrile pyrrole mite ester, mibemycin, which are dissolved in solvent and emulsifier, becomes uniform oily phase, under stiring slowly
Be added deionized water, formed WO emulsion, then it is agitated be allowed to rapid phase inversion into oil-in-water type, be cooled to room temperature and be allowed to reach
To balance, microemulsion is obtained through filtering.
As reference, the present invention provides the methods that the composition pesticide is prepared into pesticide emulsion in water, including：
Nitrile pyrrole mite ester and mibemycin are dissolved in solvent, in emulsifier at homogeneous oil phase；By deionized water, freeze proof
Agent, preservative, defoaming agent are mixed into uniform water phase, under high speed shear, oily phase are added in water phase, obtains aqueous emulsion.
As reference, the present invention provides the methods that the composition pesticide is prepared into pesticide water dispersible granules, including：
Nitrile pyrrole mite ester and mibemycin and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, add water kneading
Afterwards, it is added in pelletizer and is granulated, then obtain water dispersible granules through drying, screening again.
As reference, the present invention provides the methods that the composition pesticide is prepared into pesticide wettable, including：
Nitrile pyrrole mite ester and mibemycin and auxiliary agent and filler etc. are sufficiently mixed, after ultra-fine pulverizer disintegrating, mixed
It closes and uniformly obtains wettable powder.
The application method and dosage of composition pesticide of the present invention：It is diluted with water and makees even spraying；Dosage is tight according to pest and disease damage
Depending on pesticide effective component content in weight degree and the specific formulations of pesticide.
The present invention using mibemycin and nitrile pyrrole mite ester as the insecticidal synergistic composition of main active, can prevent and treat including
In red spider, Tetranychus urticae, Tetranychus cinnabarinus, yellow tea mite, Panonychus citri, pink tea rust mite, Mite or rust mite any one or
It is a variety of；
For the present invention by after mibemycin and nitrile pyrrole mite ester mixture, activity and insecticidal effect are not the active letters of each component
Single superposition, but have significant synergistic effect, control efficiency is improved, and extend the medicament lasting period, reduces drug cost；
Mixed Pharmacy can prevent mite class from developing drug resistance, and extend the service life of pesticide species；Good, the quick-acting to crop safety
Good, the lasting period is long, and application cost is low, meets the security requirement of pesticidal preparations.
Specific embodiment
Further describe the present invention below in conjunction with specific embodiment, the advantages and features of the present invention will be with description and
It is apparent.But examples are merely exemplary for these, and it is not intended to limit the scope of the present invention in any way.Those skilled in the art
Member it should be understood that can modify without departing from the spirit and scope of the invention to details and form of the invention or
Replacement, but these modifications and replacement are fallen within the protection scope of the present invention.
1 20% mibemycin nitrile pyrrole mite ester suspending agent (mibemycin of embodiment:Nitrile pyrrole mite ester is 19:1) system
It is standby
The thickening of raw medicine, wetting agent, dispersing agent, antifreeze, preservative, gross mass 60% is weighed by above-mentioned recipe requirements
Agent, the defoaming agent of gross mass 60% and water etc. are uniformly mixed, grinding, when partial size is at 5 μm, stops grinding, remaining increasing is added
Thick dose and defoaming agent obtain suspending agent product after adjusting uniformly.
2 10% mibemycin nitrile pyrrole mite ester suspending agent (mibemycin of embodiment:Nitrile pyrrole mite ester is 9:1) system
It is standby
55% thickening of raw medicine, wetting agent, dispersing agent, antifreeze, preservative, gross mass is weighed by above-mentioned recipe requirements
Agent, 55% defoaming agent of gross mass and water etc. are uniformly mixed, grinding, when partial size is at 5 μm, stops grinding, remaining increasing is added
Thick dose and defoaming agent obtain suspending agent product after adjusting uniformly.
3 20% mibemycin nitrile pyrrole mite ester suspending agent (mibemycin of embodiment:Nitrile pyrrole mite ester is 1:1) system
It is standby
The thickening of raw medicine, wetting agent, dispersing agent, antifreeze, preservative, gross mass 60% is weighed by above-mentioned recipe requirements
Agent, the defoaming agent of gross mass 60% and water etc. are uniformly mixed, grinding, when partial size is at 5 μm, stops grinding, remaining increasing is added
Thick dose and defoaming agent obtain suspending agent product after adjusting uniformly.
4 10% mibemycin nitrile pyrrole mite ester microemulsion (mibemycin of embodiment:Nitrile pyrrole mite ester is 9:1) system
It is standby
Raw medicine is weighed by above-mentioned recipe requirements, solvent, emulsifier, being allowed to dissolution becomes uniform oily phase, under stiring slowly
It is slow that deionized water is added, form WO emulsion, then it is agitated be allowed to rapid phase inversion into oil-in-water type, be cooled to room temperature and be allowed to
Reach balance, obtains microemulsion product through filtering.
5 20% mibemycin nitrile pyrrole mite ester microemulsion (mibemycin of embodiment:Nitrile pyrrole mite ester is 19:1) system
It is standby
Raw medicine is weighed by above-mentioned recipe requirements, solvent, emulsifier, being allowed to dissolution becomes uniform oily phase, under stiring slowly
It is slow that deionized water is added, form WO emulsion, then it is agitated be allowed to rapid phase inversion into oil-in-water type, be cooled to room temperature and be allowed to
Reach balance, obtains microemulsion product through filtering.
6 10% mibemycin nitrile pyrrole mite ester aqueous emulsion (mibemycin of embodiment:Nitrile pyrrole mite ester is 9:1) system
It is standby
Raw medicine, solvent, emulsifier are weighed by above-mentioned recipe requirements, is dissolved into homogeneous oil phase；By deionized water, antifreeze,
Preservative, defoaming agent are mixed into uniform water phase, under high speed shear, oily phase are added in water phase, obtains aqueous emulsion product.
7 20% mibemycin nitrile pyrrole mite ester aqueous emulsion (mibemycin of embodiment:Nitrile pyrrole mite ester is 1:1) system
It is standby
Raw medicine, solvent, emulsifier are weighed by above-mentioned recipe requirements, is dissolved into homogeneous oil phase；By deionized water, antifreeze,
Preservative, defoaming agent are mixed into uniform water phase, under high speed shear, oily phase are added in water phase, obtains aqueous emulsion product.
8 10% mibemycin nitrile pyrrole mite ester wettable powder (mibemycin of embodiment:Nitrile pyrrole mite ester is 9:1)
Preparation
Raw medicine, various auxiliary agents and filler etc. are weighed by above-mentioned recipe requirements to be sufficiently mixed, and after ultra-fine pulverizer disintegrating, are mixed
It closes and uniformly obtains wettable powder product.
9 20% mibemycin nitrile pyrrole mite ester wettable powder (mibemycin of embodiment:Nitrile pyrrole mite ester is 1:1)
Preparation
Raw medicine, various auxiliary agents and filler etc. are weighed by above-mentioned recipe requirements to be sufficiently mixed, and after ultra-fine pulverizer disintegrating, are mixed
It closes and uniformly obtains wettable powder product.
10 20% mibemycin nitrile pyrrole mite ester wettable powder (mibemycin of embodiment:Nitrile pyrrole mite ester is 1:
19) preparation
Raw medicine, various auxiliary agents and filler etc. are weighed by above-mentioned recipe requirements to be sufficiently mixed, and after ultra-fine pulverizer disintegrating, are mixed
It closes and uniformly obtains wettable powder product.
11 50% mibemycin nitrile pyrrole mite ester wettable powder (mibemycin of embodiment:Nitrile pyrrole mite ester is 1:
49) preparation
Raw medicine, various auxiliary agents and filler etc. are weighed by above-mentioned recipe requirements to be sufficiently mixed, and after ultra-fine pulverizer disintegrating, are mixed
It closes and uniformly obtains wettable powder product.
12 10% mibemycin nitrile pyrrole mite ester water dispersible granules (mibemycin of embodiment:Nitrile pyrrole mite ester is 9:1)
Preparation
By above-mentioned recipe requirements, raw medicine and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading,
It is added in pelletizer and is granulated, then obtain water dispersible granules product through drying, screening again.
13 10% mibemycin nitrile pyrrole mite ester water dispersible granules (mibemycin of embodiment:Nitrile pyrrole mite ester is 1:9)
Preparation
By above-mentioned recipe requirements, raw medicine and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading,
It is added in pelletizer and is granulated, then obtain water dispersible granules product through drying, screening again.
14 20% mibemycin nitrile pyrrole mite ester water dispersible granules (mibemycin of embodiment:Nitrile pyrrole mite ester is 19:
1) preparation
By above-mentioned recipe requirements, raw medicine and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading,
It is added in pelletizer and is granulated, then obtain water dispersible granules product through drying, screening again.
15 50% mibemycin nitrile pyrrole mite ester water dispersible granules (mibemycin of embodiment:Nitrile pyrrole mite ester is 49:
1) preparation
By above-mentioned recipe requirements, raw medicine and wetting agent, dispersing agent, filler etc. are subjected to co-grinding, after adding water kneading,
It is added in pelletizer and is granulated, then obtain water dispersible granules product through drying, screening again.
1 mibemycin of test example compounds the formula indoor screening test one of prevention and treatment red spider, test material with nitrile pyrrole mite ester
Material
Subjects：Red spider
Reagent agent：91% mibemycin raw medicine (Zhejiang Hisun Chemical Co., Ltd's production)
95% nitrile pyrrole mite ester raw medicine (production of Japanese Nissan chemical industry Co., Ltd.)
Two, test method
Raw medicine is configured to the test medicine needed, test method standard reference：Rower,《Farm-chemical indoor determination examination
Test the 14th part insecticidal activity of criterion insecticide test leaf dipping method (NY/T 1154.14-2008)》.First by single dose and mixed medicine
Agent is arranged 7 various concentration gradients and (on the basis of preliminary experiment result, different, concentration is combined and matched according to different agents
Gradient setting is also different
Concrete operations are as follows：
Slide infusion process.It chooses laboratory and connects feeding red spider of being commissioned to train, post the load glass of double-sided adhesive at one end with small writing brush
On piece picking adult mite, every 30.Every 2-3 slide of processing, is repeated 2 times.Medicament water is prepared in the diluted method of equivalent
At the dilution of 5-7 various concentration, then again by slide immerse medical fluid 5 seconds, dry postposition illumination box (25 ± l DEG C,
60%-70% humidity), 3 repetitions of every processing are every to repeat test worm 20.It takes out afterwards for 24 hours and checks dead borer population.Death standard is with needle
Light thorn is without autonomic response.Probability value, drug concentration are converted by 3 duplicate average mortalities
TTI=TIA×PA+TIB×PB
It is converted into logarithm, then presses Chinese agriculture professional standard NY/T 1154.7-2006《Farm-chemical indoor determination examination
Test the 7th part of criterion insecticide：The synergy measurement of mixture》Method calculate regression equation, related coefficient, co-toxicity coefficient
Deng.
ATI：Mixture surveys toxicity index:
S：The LC of standard pesticide agent50∶
M：The LC50 of mixture:
TTI：Mixtures theoretical toxicity index:
TIA：A medicament toxicity index:
PA：Percentage composition of the A medicament in mixture:
TIB：B medicament toxicity index:
PB：Percentage composition of the B medicament in mixture:
CTC：Co-toxicity coefficient.
The co-toxicity coefficient (CTC) >=120 of compound preparation shows as synergistic effect；CTC≤80 show as antagonism；80 <
CTC < 120 shows as summation action.
Three, test result
Test and calculated result are as shown in table 1.
The The Toxicity Determination result of each single dose of table 1 and its mixture to red spider
The Toxicity Determination result shows：All there is superior prevention and treatment to imitate to red spider for mibemycin and nitrile pyrrole mite ester
Fruit, each group compounding agent still has red spider prevents and kill off activity well.After medicine for 24 hours mibemycin insecticidal activity compared with nitrile pyrrole mite ester
It is high.Nitrile pyrrole mite ester and mibemycin proportion 1:When 9, co-toxicity coefficient 182.74, synergistic effect is most strong.
2 mibemycin of test example compounds the field control effectiveness test of prevention and treatment red spider with nitrile pyrrole mite ester
Test objective：The nitrile pyrrole mite ester and mibemycin compound preparation for understanding different ratio are to the Field information of red spider
Effect determines optimum quantum of utilization and application method.
One, test material
Subjects：Red spider
For studying object：Citrus
Two, test method
Referring to People's Republic of China's agricultural industry criteria《Pesticide field efficacy medicine test criterion (one)》GB/T17980.4-
2000。
1, environmental condition：Test site is located at City of Taizhou spring town, and experimental field soil property is clay, and topography is flat,
Middle fertility.
2, test and comparison medicament are shown in Table 2
Test medicine and comparison medicament used in 2 field trial of table
3, experimental design：
Experimental design is shown in Table 3.
3 reagent agent experimental design of table
Plot area and repetition：3 repetitions of every group of setting, 3 tree (18m of each repetition2)。
Application method：Using spray method to Citrus leaf front and back sides even spraying.It is carried out with mulch as barrier when application
Isolation, to prevent float of mist droplet.
Spraying time and number：Mite mouthful it is intensive, be evenly distributed and when mite amount is continuously increased applies a medicine prevention and treatment, apply altogether
Medicine, is attached most importance to blade, and blade obverse and reverse sides are uniformly sprayed thoroughly, is sprayed onto fruit tree and is dripped.
Control time and number：Adult radix is investigated before application, respectively at the worm in 1d, 3d, 7d investigation singling after application
Mouth quantity.
Investigation method：Every plant of every cell tree by East, West, South, North, in investigate 5~10 epiphyllous Mobile Forms mites
Number, and illustrate the type of taken leaf.Blade is checked with hand magnifier, records Mobile Forms mite quantity.
Drug effect calculation method：
In formula：
PT-control efficiency, unit are percentage (%)；
PT0Mite number before-chemicals treatment district medicine；
PT1Mite number after-chemicals treatment district medicine；
CK0Mite number before-blank district is administered；
CK1Mite number after the application of-blank district.
Calculated result retains 2 significant digits.As a result for statistical analysis using poor (DMRT) method of the new multipole of Deng Kenshi.
Biological statistical method：Notable difference test uses " DMRT " method；
Crop is directly affected：Each processing all shows citrus safety without phytotoxicity.
Have no that processing group has adverse effect to other non-target organisms when test.
Three, field test results
Field test results are shown in Table 4.
The test result of mibemycin and nitrile pyrrole mite ester compound preparation the prevention and treatment red spider of 4 different ratio of table
Note：Lowercase letter indication difference significance degree is P=0.05, and capitalization indicates that significant difference degree is P=
0.01。
Field control effectiveness test result according to table 4 is visible：The mibemycin of different ratio compounds system with nitrile pyrrole mite ester
Agent has favorable effect, and better than 1000 times of 3% mibemycin microemulsion, 30% to citrus red mite under experimental concentration
Nitrile pyrrole mite ester suspending agent 2000 is again to the control efficiency of citrus red mite, wherein 30% nitrile pyrrole mite ester mibemycin dosage form
(1:9) 1500 times it is best to citrus red mite preventive effect, 1 day after medicine, 3 days, 7 days preventive effects be respectively 87.63%, 95.68%,
93.44%.
Claims (10)
1. a kind of agricultural chemical composition for disinsection, which is characterized in that its active constituent is made of nitrile pyrrole mite ester and mibemycin.
2. agricultural chemical composition for disinsection described in accordance with the claim 1, which is characterized in that the quality of nitrile pyrrole mite ester and mibemycin
Ratio is (1~49): (1~49).
3. agricultural chemical composition for disinsection according to claim 2, which is characterized in that the quality of nitrile pyrrole mite ester and mibemycin
Ratio is (1~9): (1~49).
4. agricultural chemical composition for disinsection described in accordance with the claim 3, which is characterized in that the quality of nitrile pyrrole mite ester and mibemycin
Ratio is 1: (9~49).
5. agricultural chemical composition for disinsection according to claim 4, which is characterized in that the quality of nitrile pyrrole mite ester and mibemycin
Ratio is 1: 9.
6. a kind of method for preparing any one of claim 1-5 composition pesticide, which is characterized in that will be in active constituent
Acceptable auxiliary material on pesticidal preparations is added, is prepared into various pesticidal preparations.
7. according to the method for claim 6, which is characterized in that the auxiliary material includes emulsifier, wetting dispersing agent, thickening
Agent, antifreezing agent, stabilizer, preservative, disintegrating agent or binder；Preferably, the emulsifier is selected from nonionic surfactant
Castor oil ethylene oxide adduct, nonylphenol polyoxyethylene ether, fatty alcohol polyoxyethylene ether, phenethyl phenol polyoxyethylene polyoxy third
One of alkene ether, APES formaldehyde condensation product are a variety of；The wetting dispersing agent is selected from dodecyl sulphate
Sodium, pull open powder, alkylphenol-polyethenoxy base ether, the salt of naphthalene sulfonic acid-formaldehyde condensation product or polyoxyethylene groups polyethenoxy ether block are total
The mixture that one or more of polymers is formed according to arbitrary proportion；It is fine that the thickener is selected from xanthan gum, carboxymethyl
Tie up one of element, Sodium Polyacrylate, aluminum magnesium silicate, gaseous silicon oxide or attapulgite or or kind；The antifreezing agent is selected from
Any one or more than one in ethylene glycol, propylene glycol, glycerol, glycerol-ether diglycol or methyl propylene diglycol is pressed
According to the mixture of arbitrary proportion composition；The stabilizer is selected from 2,6 di tert butyl 4 methyl phenol or citric acid or butyl
Any one or more in hydroxyanisole；The disintegrating agent appointing in urea, bentonite, montmorillonite or sodium alginate
It anticipates one or more；The binder is selected from gelatin, Arabic gum, xanthan gum, sodium tripolyphosphate, phenolic resin or polyethylene
One of pyrrolidones is a variety of；The filler is kaolin.
8. according to the method for claim 6, which is characterized in that the pesticidal preparations include suspending agent, wettable powder,
Water dispersible granules, microemulsion or aqueous emulsion.
9. according to the method for claim 8, which is characterized in that the preparation method of the agricultural chemicals suspension agent, including：By nitrile
Pyrrole mite ester, mibemycin and wetting agent, dispersing agent, antifreeze, preservative, thickener, defoaming agent and water etc., which are uniformly mixed, to be ground
Mill stops grinding when partial size is at 5 μm, obtains suspending agent after adding thickener and defoaming agent adjusting uniformly；
The preparation method of the microemulsion, including：By nitrile pyrrole mite ester, mibemycin be dissolved in solvent and emulsifier at
For uniform oily phase, it is slowly added into deionized water under stiring, forms WO emulsion, then agitated is allowed to rapid phase inversion
At oil-in-water type, it is cooled to room temperature and makes up to balance, obtains microemulsion through filtering；
The preparation method of the pesticide emulsion in water, including：Nitrile pyrrole mite ester and mibemycin are dissolved in solvent, in emulsifier
At homogeneous oil phase；Deionized water, antifreeze, preservative, defoaming agent are mixed into uniform water phase, it, will under high speed shear
Oily phase is added in water phase, and aqueous emulsion is made；
The preparation method of the pesticide water dispersible granules, including：By nitrile pyrrole mite ester and mibemycin and wetting agent, dispersing agent
And filler carries out co-grinding, adds water and is granulated in addition pelletizer after mediating, then obtains moisture through drying, screening
Shot agent；
The preparation method of the pesticide wettable, including：Nitrile pyrrole mite ester and mibemycin are filled with auxiliary agent and filler
Divide mixing, after ultra-fine grinding, is uniformly mixed and obtains wettable powder.
10. any one of the claim 1-5 composition pesticide is killing the purposes in acarid.
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| Application Number | Priority Date | Filing Date | Title |
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| CN201811000002.5A CN108849914A (en) | 2018-08-30 | 2018-08-30 | Agricultural chemical composition for disinsection and its preparation method and application |
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| CN201811000002.5A CN108849914A (en) | 2018-08-30 | 2018-08-30 | Agricultural chemical composition for disinsection and its preparation method and application |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114431238A (en) * | 2020-11-04 | 2022-05-06 | 浙江省化工研究院有限公司 | Acaricide composition |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012004293A2 (en) * | 2010-07-08 | 2012-01-12 | Bayer Cropscience Ag | Insecticide and fungicide active ingredient combinations |
| CN104920393A (en) * | 2015-05-19 | 2015-09-23 | 陕西上格之路生物科学有限公司 | Acaricidal composition containing cyenopyrafen and abamectin |
| CN105766925A (en) * | 2014-12-25 | 2016-07-20 | 中化农化有限公司 | Pesticide composition comprising cyenopyrafen, and application thereof |
-
2018
- 2018-08-30 CN CN201811000002.5A patent/CN108849914A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2012004293A2 (en) * | 2010-07-08 | 2012-01-12 | Bayer Cropscience Ag | Insecticide and fungicide active ingredient combinations |
| CN105766925A (en) * | 2014-12-25 | 2016-07-20 | 中化农化有限公司 | Pesticide composition comprising cyenopyrafen, and application thereof |
| CN104920393A (en) * | 2015-05-19 | 2015-09-23 | 陕西上格之路生物科学有限公司 | Acaricidal composition containing cyenopyrafen and abamectin |
Non-Patent Citations (1)
| Title |
|---|
| 崔江虎等: "天然产物在作物保护中的应用概述（下）", 《世界农药》 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114431238A (en) * | 2020-11-04 | 2022-05-06 | 浙江省化工研究院有限公司 | Acaricide composition |
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