CN108837283A - Stem bronchi cell precise positioning slow-released system - Google Patents
Stem bronchi cell precise positioning slow-released system Download PDFInfo
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- CN108837283A CN108837283A CN201810327710.3A CN201810327710A CN108837283A CN 108837283 A CN108837283 A CN 108837283A CN 201810327710 A CN201810327710 A CN 201810327710A CN 108837283 A CN108837283 A CN 108837283A
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- stem cell
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M31/00—Devices for introducing or retaining media, e.g. remedies, in cavities of the body
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- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
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- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
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- Veterinary Medicine (AREA)
- Radiation-Therapy Devices (AREA)
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Abstract
The present invention discloses stem bronchi cell precise positioning slow-released system,Including endoscopic system,Endoscopic system is inserted into lung by flexible light guide bundles,The information of lung is transmitted to the display screen of endoscopic system by the optic probe of light guide bundles bottom,Visual display screen provides for operation accurately to be operated,Light guide bundles are internally provided with the anesthesia slow-released system that patient comfort is promoted when operation,The inside of light guide bundles is additionally provided with stem cell slow-released system,Acute respiratory distress syndrome is effectively treated by precisely discharging stem cell,It is novel in design,Using medical endoscope,Enable the variation that lung is observed when operation,Make stem cell release at effective position,To reach better therapeutic effect,And operation uses local anaesthesia,Promote the comfort level of patient,Practical performance is excellent,It is a kind of good innovation scheme,It is very promising for marketing..
Description
Technical field
It is slow more particularly to stem bronchi cell precise positioning the present invention relates to treatment acute respiratory distress syndrome method
Release system.
Background technique
Acute respiratory distress syndrome (ARDS) is as caused by intrapulmonary reason and/or extrapulmonary reason, with intractable hypoxemia
Mass formed by blood stasis is the clinical syndrome of notable feature, is received much attention because of high case fatality rate.The cause of disease of acute respiratory distress syndrome is various,
Different pathogeny induced Acute Respiratory Distress Syndrome(RDS) pathogenesis is also had nothing in common with each other.Clinical manifestation be in more Acute onset, breathing it is embarrassed
Compel and be difficult to the hypoxemia etc. corrected with conventional oxygen therapy；Currently, " Berlin definition " is mostly used to pay a home visit ARDS in the world
The layering of disconnected and severity, and antidiastole need to be carried out with a variety of diseases.Clinical examination content is related to：Diagnosis and differential diaggnosis,
Treatment monitoring and guiding treatment, severe degree and prognosis evaluation and test etc.；Treatment of ARDS includes that mechanical ventilation is controlled
It treats and still is continuing to explore with on-mechanical ventilation therapy two major classes, effective treatment method.
The cause of disease of acute respiratory distress syndrome includes intrapulmonary reason and extrapulmonary reason two major classes.Intrapulmonary reason includes：Lung
Inflammation, accidentally suction, contusion of lung, drowning and noxious material sucking, lung other factor include：Severe systemic infection, severe multiple injuries (multiple bone
Folding, flail chest, serious brain traumatism and burn), shock, high-risk operation (openheart surgery, main artery operation etc.), massive transfusion, medicine
Object is poisoned, pancreatitis and cardiopulmonary bypass are postoperative etc..In addition, the cause of disease of ARDS can also be divided into biological cause according to pathogenic former different
Cause of disease and abiotic pathogenic former two major classes：It includes mainly multiple pathogens that biology, which causes a disease former, such as bacterium, virus, fungi, atypia
Pathogen and partial injury associated molecular pattern (DAMPs), malignant tumour etc.；It is abiotic it is pathogenic it is former mainly include acidic materials,
Drug, toxic gas sucking, mechanical ventilation associated injury etc..
Mechanical ventilation is the essential therapeutic arsenals of Patients with ARDS.Not according to mechanical ventilation mode
Together, invasive ventilation and Invasive vent ilation can be divided into, invasive ventilation relies on mask and ventilates, and Invasive vent ilation then relies on trachea cannula
Or catheter for tracheostomy is ventilated, the two selection need to rely on the specific state of an illness and determine opportunity；Currently, being directed to acute respiratory distress
The ventilation tactics of syndrome patient mainly include the following contents：Lung preversation ventilation strategies (small tidal volume ventilation [LTVV], pressure
Power limit ventilation, permitted deformation [PHC], inverse ventilation, PEEP application etc.), Open lung Approach (particular technique packet
It includes：Lung recruitment [RM], best PEEP application and selection of Mechanical Ventilation Modes etc.) and mechanical ventilation adjuvant treatment (air flue
Innerlich anwenden [nitric oxide, prostaglandin], prone-position ventilation, external mould lung oxygen conjunction technology etc.).
Though the on-mechanical ventilation therapy means of acute respiratory distress syndrome are more, its reliable curative effect is not yet determined so far.
On-mechanical ventilation therapy means include：Edema with the lung involved is removed and liquid management, alveolar surfactant replacement therapy, statins
Using the application of, glucocorticoid, anti-coagulants application, antioxidant and the application of enzyme inhibitor, blood purification treatment, nutritional intervention
Deng；But the effect for the treatment of is not ideal, there is deficiencies.
In conclusion in view of the drawbacks of the prior art, it is accordingly required in particular to stem bronchi cell precise positioning slow-released system, with solution
Certainly the deficiencies in the prior art.
Summary of the invention
Aiming at the problems existing in the prior art, use in practice is influenced, the present invention proposes that stem bronchi cell is accurate
Positioning and slow release system, it is novel in design, using visual operation, stem cell is accurately injected to intrapulmonary, is controlled with reaching optimal
Therapeutic effect has solved the defect of the prior art.
To achieve the goals above, technical scheme is as follows：
Stem bronchi cell precise positioning slow-released system, including endoscopic system, endoscopic system are led by flexible
Light beam is inserted into lung, and the information of lung is transmitted to the display screen of endoscopic system by the optic probe of light guide bundles bottom, visualizes
Display screen provide and accurately operate for operation, light guide bundles are internally provided with the anesthesia sustained release that patient comfort is promoted when operation
System, the inside of light guide bundles are additionally provided with stem cell slow-released system, effectively treat acute respiration by precisely discharging stem cell
Distress syndrome, stem cell slow-released system are set to the lower section of anesthesia slow-released system, anaesthetize slow-released system, stem cell slow-released system
The external triple valve in light guide bundles surface is connected by conduit, the corresponding conduit of triple valve connects corresponding infusion system.
Reticular structure is used in stem cell slow-released system of the present invention, the hole of reticular structure is set as stem cell release
Mouthful, the diameter of stem cell liberation port is equal to the diameter of stem cell.
Further, the filter membrane for including of the anesthesia slow-released system, the surface of filter membrane are provided with several sustained release holes,
The diameter for being sustained hole uses nanoscale.
Further, the side of the optic probe is provided with positioning device, and positioning device is positioned using B ultrasound or CT is fixed
Position.
Further, the treatment method of stem bronchi cell precise positioning slow-released system：First in the light guide bundles of endoscope
Inside is respectively connected to anesthesia slow-released system, stem cell delays system, the optic probe side mounting and positioning device of endoscope bottom, fiber crops
Liquor-saturated slow-released system, stem cell slow-released system connect the external triple valve in light guide bundles surface by conduit, gate in treatment
Triple valve injects anaesthetic to anesthesia slow-released system, and the speed of injection can flexibly be controlled by syringe pump, promotes operation patients
Comfort level, since the sustained release hole of anesthesia slow-released system uses nanoscale, so anesthesia can be slowly diffused in vivo, then
The light guide bundles of endoscope are inserted in the lung of human body, during insertion, can directly be seen by the optic probe of endoscope
To position of the endoscope in people, then reaches between treatment position, stem cell, Er Qiegan are implanted into human body by triple valve
Cell also uses slow-released system, and the diameter of stem cell is identical with the diameter of stem cell liberation port, can accurately discharge stem cell,
To reach optimal therapeutic effect.
The beneficial effects of the invention are as follows：This product is novel in design, using medical endoscope, enables to observe lung when operation
Variation, make stem cell release at effective position, to reach better therapeutic effect, and perform the operation and use local anaesthesia, promoted
The comfort level of patient, practical performance is excellent, is a kind of good innovation scheme, is very promising for marketing..
Detailed description of the invention
The following describes the present invention in detail with reference to the accompanying drawings and specific embodiments：
Fig. 1 is the structural diagram of the present invention；
Fig. 2 is stem cell slow-released system structure chart of the present invention；
Fig. 3 is present invention anesthesia slow-released system structure chart；
100- endoscopic system in figure, 110- light guide bundles, 120- triple valve, 130- anaesthetize slow-released system, 140- stem cell
Slow-released system, 150- positioning device, 160- optic probe, 141- stem cell liberation port, 131- filter membrane, 132- are sustained hole.
Specific embodiment
In order to be easy to understand the technical means, the creative features, the aims and the efficiencies achieved by the present invention, tie below
Conjunction is specifically illustrating, and the present invention is further explained.
Referring to Fig. 1, stem bronchi cell precise positioning slow-released system, including endoscopic system 100, endoscopic system 100
It is inserted into lung by flexible light guide bundles 110, the information of lung is transmitted to interior by the optic probe 160 of 110 bottom of light guide bundles
The display screen of endoscope system 100, visual display screen are provided for operation and are accurately operated, and light guide bundles 110 are internally provided with
The anesthesia slow-released system 130 of patient comfort is promoted when operation, the inside of light guide bundles 110 is additionally provided with stem cell slow-released system
140, acute respiratory distress syndrome effectively is treated by precisely discharging stem cell, stem cell slow-released system 140 is set to fiber crops
The lower section of liquor-saturated slow-released system 130, anesthesia slow-released system 130, stem cell slow-released system 140 connect light guide bundles surface by conduit
External triple valve 120, the corresponding conduit of triple valve 120 connect corresponding infusion system.
Stem cell slow-released system 140 uses reticular structure, and the hole of reticular structure is set as stem cell liberation port 141, does thin
The diameter of born of the same parents' liberation port 141 is equal to the diameter of stem cell.
The filter membrane 131 for including of slow-released system 130 is anaesthetized, the surface of filter membrane 131 is provided with several sustained release holes 132,
The diameter for being sustained hole 132 uses nanoscale.
The side for learning probe 160 is provided with positioning device 150, and positioning device 150 is positioned using B ultrasound or CT positioning.
The treatment method of stem bronchi cell precise positioning slow-released system：Distinguish first in the inside of the light guide bundles of endoscope
Access anesthesia slow-released system, stem cell delay system, the optic probe side mounting and positioning device of endoscope bottom, anesthesia sustained release system
System, stem cell slow-released system connect the external triple valve in light guide bundles surface by conduit, gate triple valve pair in treatment
It anaesthetizes slow-released system and injects anaesthetic, the speed of injection can flexibly be controlled by syringe pump, due to anaesthetizing the sustained release of slow-released system
Hole uses nanoscale, so anesthesia can be slowly diffused in vivo, then the light guide bundles of endoscope is inserted in the lung of human body
Portion can directly be seen that position of the endoscope in people by the optic probe of endoscope, then reach during insertion
Between designated position, stem cell is implanted into human body by triple valve, and stem cell also uses slow-released system, stem cell it is straight
Diameter is identical with the diameter of stem cell liberation port, can accurately discharge stem cell, improves the comfort level of patient's operation.
The present invention is local anaesthesia during the entire process of operation using anesthesia slow-released system, and slight needle is fixed, and seldom answers
Swash reaction, and uses double positioner, the optic probe and positioning device of endoscopic system, to reach visual hand
Art effectively discharges stem cell in lung, to reach optimal therapeutic effect, and anaesthetizes slow-released system and stem cell sustained release system
System is sustained release, and sustained release improves the comfort level of patient, to reach optimal therapeutic effect.
Stem cell is cells of origin, and stem cell is the cell with proliferation and differentiation potential, has self-renewing duplication
Ability, well differentiated functioning cell can be generated, briefly, it is that a kind of have multi-lineage potential and self-replacation
The original neoblast of ability is the initial cell to form each histoorgan of mammal.Stem cell is morphologically
With general character, be generally circular in shape or ellipse, cell volume is small, and core is relatively large, and nucleus is mostly euchromatin, and have compared with
High telomerase activation.Stem cell can be divided into embryonic stem cell and adult stem cell, and the principle of the present invention is to lead to stem cell
It crosses stem cell slow-released system effectively to discharge in lesions position, visualized operation, precisely treat, rapid healing is acute to exhale to reach
Inhale the purpose of Distress syndrome.
The beneficial effects of the invention are as follows：This product is novel in design, using medical endoscope, enables to observe lung when operation
Variation, make stem cell release at effective position, to reach better therapeutic effect, and perform the operation and use local anaesthesia, promoted
The comfort level of patient, practical performance is excellent, is a kind of good innovation scheme, is very promising for marketing..
It should be understood by those skilled in the art that the present invention is not limited to the above embodiments, above-described embodiment and explanation
It is merely illustrated the principles of the invention described in book, the present invention also has each without departing from the spirit and scope of the present invention
Kind changes and improvements, these changes and improvements all fall within the protetion scope of the claimed invention.The claimed scope of the invention by
Appended claims and its equivalent define.
Claims (5)
1. stem bronchi cell precise positioning slow-released system, including endoscopic system, it is characterised in that：Endoscopic system passes through can
Curved light guide bundles are inserted into lung, and the information of lung is transmitted to the display of endoscopic system by the optic probe of light guide bundles bottom
Screen, visual display screen are provided for operation and are accurately operated, and light guide bundles promote patient comfort when being internally provided with operation
Anesthesia slow-released system, the inside of light guide bundles is additionally provided with stem cell slow-released system, is effectively controlled by precisely discharging stem cell
Acute respiratory distress syndrome is treated, stem cell slow-released system is set to the lower section of anesthesia slow-released system, and anesthesia slow-released system is done carefully
Born of the same parents' slow-released system connects the external triple valve in light guide bundles surface by conduit, and the corresponding conduit connection of triple valve is corresponding
Infusion system.
2. stem bronchi cell precise positioning slow-released system according to claim 1, it is characterised in that：The stem cell is slow
Release system uses reticular structure, and the hole of reticular structure is set as stem cell liberation port, and the diameter of stem cell liberation port is equal to dry thin
The diameter of born of the same parents.
3. stem bronchi cell precise positioning slow-released system according to claim 1, it is characterised in that：The anesthesia sustained release
The filter membrane for including of system, the surface of filter membrane are provided with several sustained release holes, are sustained the diameter in hole using nanoscale.
4. stem bronchi cell precise positioning slow-released system according to claim 1, it is characterised in that：The optic probe
Side be provided with positioning device, positioning device is positioned using B ultrasound or CT positioning.
5. the treatment method of stem bronchi cell precise positioning slow-released system：It is characterized in that：First in the light guide bundles of endoscope
Inside be respectively connected to anesthesia slow-released system, stem cell delay system, the optic probe side mounting and positioning device of endoscope bottom,
It anaesthetizes slow-released system, stem cell slow-released system and the external triple valve in light guide bundles surface is connected by conduit, gated in treatment
Triple valve is crossed to anesthesia slow-released system injection anaesthetic, the speed of injection can flexibly be controlled by syringe pump, promote operation patients
Comfort level, since the sustained release hole of anesthesia slow-released system uses nanoscale, thus anesthesia being diffused in vivo slowly, so
The light guide bundles of endoscope are inserted in the lung of human body afterwards, it, can be direct by the optic probe of endoscope during insertion
See position of the endoscope in people, then reaches between treatment position, stem cell is implanted into human body by triple valve, and
Stem cell also uses slow-released system, and the diameter of stem cell is identical with the diameter of stem cell liberation port, can accurately discharge dry thin
Born of the same parents, to reach optimal therapeutic effect.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810327710.3A CN108837283A (en) | 2018-04-12 | 2018-04-12 | Stem bronchi cell precise positioning slow-released system |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201810327710.3A CN108837283A (en) | 2018-04-12 | 2018-04-12 | Stem bronchi cell precise positioning slow-released system |
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| Publication Number | Publication Date |
|---|---|
| CN108837283A true CN108837283A (en) | 2018-11-20 |
Family
ID=64212038
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201810327710.3A Pending CN108837283A (en) | 2018-04-12 | 2018-04-12 | Stem bronchi cell precise positioning slow-released system |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN112244957A (en) * | 2020-10-29 | 2021-01-22 | 安徽省立医院(中国科学技术大学附属第一医院) | Continuous slow-release administration indwelling tube with puncture sheath |
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Application publication date: 20181120 |