CN108815498A - A kind of pharmaceutical composition and the preparation method and application thereof for treating pharyngitis - Google Patents

A kind of pharmaceutical composition and the preparation method and application thereof for treating pharyngitis Download PDF

Info

Publication number
CN108815498A
CN108815498A CN201811073967.7A CN201811073967A CN108815498A CN 108815498 A CN108815498 A CN 108815498A CN 201811073967 A CN201811073967 A CN 201811073967A CN 108815498 A CN108815498 A CN 108815498A
Authority
CN
China
Prior art keywords
weight
parts
radix
pharyngitis
pharmaceutical composition
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201811073967.7A
Other languages
Chinese (zh)
Inventor
王海平
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
China Merchants State Incubator Group Ltd
Original Assignee
China Merchants State Incubator Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by China Merchants State Incubator Group Ltd filed Critical China Merchants State Incubator Group Ltd
Priority to CN201811073967.7A priority Critical patent/CN108815498A/en
Publication of CN108815498A publication Critical patent/CN108815498A/en
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535—Perilla (beefsteak plant)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/646—Arachnids, e.g. spiders, scorpions, ticks or mites
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/63—Arthropods
    • A61K35/648—Myriapods, e.g. centipedes or millipedes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56—Materials from animals other than mammals
    • A61K35/65—Amphibians, e.g. toads, frogs, salamanders or newts
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/236—Ligusticum (licorice-root)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/238—Saposhnikovia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/26—Aristolochiaceae (Birthwort family), e.g. heartleaf
    • A61K36/268—Asarum (wild ginger)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/285—Aucklandia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/34—Campanulaceae (Bellflower family)
    • A61K36/346—Platycodon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/35—Caprifoliaceae (Honeysuckle family)
    • A61K36/355—Lonicera (honeysuckle)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/42—Cucurbitaceae (Cucumber family)
    • A61K36/428—Trichosanthes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534—Mentha (mint)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/539—Scutellaria (skullcap)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/60—Moraceae (Mulberry family), e.g. breadfruit or fig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/63—Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634—Forsythia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/736—Prunus, e.g. plum, cherry, peach, apricot or almond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/78—Saururaceae (Lizard's-tail family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/80—Scrophulariaceae (Figwort family)
    • A61K36/808—Scrophularia (figwort)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/81—Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815—Lycium (desert-thorn)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8966—Fritillaria, e.g. checker lily or mission bells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8968—Ophiopogon (Lilyturf)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • A61K36/8969—Polygonatum (Solomon's seal)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/906—Zingiberaceae (Ginger family)
    • A61K36/9068—Zingiber, e.g. garden ginger
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30—Extraction of the material
    • A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction

Abstract

The invention belongs to technical field of medicine, and in particular to a kind of pharmaceutical composition for treating pharyngitis, and preparation method is further disclosed, and its is used to prepare the purposes of the external preparation for the treatment of pharyngitis.The pharmaceutical composition for the treatment of pharyngitis of the present invention, with perilla leaf, Siraitia grosvenorii, fritillaria thunbergii, radix scutellariae, rhizoma polygonati, Rhizoma Chuanxiong, radix aucklandiae, honeysuckle, cordate houttuynia, Fructus Forsythiae, dried orange peel, campanulaceae, almond, peppermint, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, bombyx batryticatus, loquat, fig, Radix Ophiopogonis, radix scrophulariae, asarum, ginger, radix saposhnikoviae is traditional Chinese medicinal components, and with centipede, scorpio and the dried venom of toads are that raw material extracts insect protein, give full play to the pharmacological property of each component, utilize each ingredient drug effect monarch, minister, assistant, effective cooperation between being allowed to, the effect of it treats pharyngitis is played altogether, to urgency, chronic pharyngitis has preferable therapeutic effect.

Description

A kind of pharmaceutical composition and the preparation method and application thereof for treating pharyngitis
Technical field
The invention belongs to technical field of medicine, and in particular to a kind of pharmaceutical composition for treating pharyngitis, and further Open preparation method, and its it is used to prepare the purposes of the external preparation for the treatment of pharyngitis.
Background technique
Pharyngitis (pharyngitis) is pharyngeal nonspecific inflammation, is that various microorganism infections are pharyngeal and generate inflammation General designation, can individualism, can also with rhinitis, tonsillitis and laryngitis and deposit, or be the premonitory symptom of certain diseases.
Pharyngitis is commonly divided into acpuei pharyngitis and chronic pharyngitis.Acpuei pharyngitis is the acute of pharyngeal mucous membrane and sub-mucosal tissues Inflammation, pharynx lymphoid tissue are often involved, and inflammation early stage can limit to, and can be related to entire pharyngeal cavity, often with disease progression with autumn and winter and winter The friendship in spring is more typical；It is mainly shown as pharyngeal drying, scorching hot, pain, it is obvious to swallow pain, congestion of throat swelling etc..Chronic pharynx Scorching to be divided into chronic simple pharyngitis, chronic hypertrophic pharyngitis and atrophic pharyngitis again, wherein chronic simple pharyngitis is more common, Lesion mainly in mucous layer, shows as pharyngeal mucous membrane chronic congestion, connective tissue proliferation under mucous membrane and mucous membrane, mucous gland can fertilizer Greatly, secreting function is hyperfunction, and mucilage secretion increases；Patient often brings up glutinous phlegm in pharynx, or feels pharyngeal and have foreign body sensation, can not cough up, swallows Under not, common adult, the course of disease is long, easy to recur, and symptom is obstinate, it is more difficult to cure.
The principal pathogenetic reason of pharyngitis is virus and bacterium infection, and contacts mostly by droplet or directly and infect.In addition, complete Body resistance weakens, such as fatigue, suffer from cold, excessive drinking and smoking be often also pharyngitis one of inducement, pharyngitis also can secondary to catching a cold or Acute tonsillitis.And acpuei pharyngitis recurrent exerbation or treatment are not thorough and adjacent organs lesion stimulation such as nasosinusitis, almond Body inflammation, nasopharyngitis, tracheitis etc. can also develop as chronic pharyngitis.Excessive drinking and smoking, maror, smog, dust and pernicious gas Stimulation is also common disease factor.
Currently, the treatment for pharyngitis, doctor trained in Western medicine is mainly anti-inflammatory using topical application, antibacterial or antiviral drugs, so And this kind of drug has more or less side effect, and certain injury is caused to liver and kidney and other organs, is unsuitable for long-term It takes.And Chinese medicine then achieves preferable therapeutic effect and public praise against the succession of many years.
Summary of the invention
For this purpose, technical problem to be solved by the present invention lies in a kind of pharmaceutical composition for treating pharyngitis is provided, one is gone forward side by side Walk open preparation method.
In order to solve the above technical problems, a kind of pharmaceutical composition for treating pharyngitis of the present invention, the pharmaceutical composition The bulk pharmaceutical chemicals of object form：Perilla leaf 25-35 parts by weight, Siraitia grosvenorii 25-35 parts by weight, fritillaria thunbergii 20-30 parts by weight, radix scutellariae 4-8 parts by weight, rhizoma polygonati 10-15 parts by weight, Rhizoma Chuanxiong 4-8 parts by weight, radix aucklandiae 4-8 parts by weight, honeysuckle 4-8 parts by weight, cordate houttuynia 4-8 parts by weight, Fructus Forsythiae 10-15 parts by weight, dried orange peel 4-8 parts by weight, campanulaceae 4-8 parts by weight, almond 20-30 parts by weight, peppermint 4-8 Parts by weight, Snakegourd Fruit 15-25 parts by weight, Radix Glehniae 10-15 parts by weight, root bark of Chinese wolf-berry 4-8 parts by weight, bombyx batryticatus 25-35 parts by weight, loquat 4-8 parts by weight, fig 10-15 parts by weight, Radix Ophiopogonis 25-35 parts by weight, radix scrophulariae 10-15 parts by weight, asarum 4-8 parts by weight, life Ginger 10-15 parts by weight, radix saposhnikoviae 4-8 parts by weight, centipede 0.005-0.01 parts by weight, scorpio 0.02-0.04 parts by weight, the dried venom of toads 0.0001-0.0002 parts by weight.
Preferably, the bulk pharmaceutical chemicals composition of the pharmaceutical composition of the treatment pharyngitis includes：30 parts by weight of perilla leaf, arhat 30 parts by weight of fruit, 24 parts by weight of fritillaria thunbergii, 6 parts by weight of radix scutellariae, 12 parts by weight of rhizoma polygonati, 6 parts by weight of Rhizoma Chuanxiong, 6 parts by weight of radix aucklandiae, gold 6 parts by weight of honeysuckle flower, 6 parts by weight of cordate houttuynia, 12 parts by weight of Fructus Forsythiae, 6 parts by weight of dried orange peel, 6 parts by weight of campanulaceae, 24 parts by weight of almond, 6 parts by weight of peppermint, 20 parts by weight of Snakegourd Fruit, 12 parts by weight of Radix Glehniae, 6 parts by weight of the root bark of Chinese wolf-berry, 30 parts by weight of bombyx batryticatus, 6 weight of loquat Part, 12 parts by weight of fig, 30 parts by weight of Radix Ophiopogonis, 12 parts by weight of radix scrophulariae, 6 parts by weight of asarum, 12 parts by weight of ginger, windproof 6 weights Measure part, 0.0075 parts by weight of centipede, 0.03 parts by weight of scorpio, 0.00015 parts by weight of the dried venom of toads.
The invention also discloses the purposes that the pharmaceutical composition is used to prepare the pharmaceutical preparation for the treatment of pharyngitis.
It, can according to clinic made of common process the invention also discloses customary adjuvant is added by the pharmaceutical composition The pharmaceutical preparation of the treatment pharyngitis of receiving.
Specifically, the pharmaceutical preparation includes oral solution, capsule, tablet.
The invention also discloses a kind of methods of pharmaceutical preparation for preparing the treatment pharyngitis, include the following steps：
(1) a selected amount of perilla leaf, Siraitia grosvenorii, fritillaria thunbergii, radix scutellariae, rhizoma polygonati, Rhizoma Chuanxiong, radix aucklandiae, honeysuckle, fish raw meat are taken It is grass, Fructus Forsythiae, dried orange peel, campanulaceae, almond, peppermint, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, bombyx batryticatus, loquat, fig, Radix Ophiopogonis, radix scrophulariae, thin Pungent, ginger, radix saposhnikoviae, and add water to be impregnated and boiled respectively, after collecting filtrate and being concentrated, poly- propylhomoserin salt is added and honey is mixed It is even, Chinese medical extract is obtained, it is spare；
(2) a selected amount of centipede, scorpio and the dried venom of toads are taken, water is added to extract, after collecting filtrate and being freeze-dried, system Freeze-dried powder is obtained, it is spare；
(3) gained Chinese medical extract and the freeze-dried powder are mixed, customary adjuvant is added, points out clinic according to common process Upper acceptable preparation.
In the step (1), the soaking step time is 30-60min.
In the step (1), in the tanning step, the Siraitia grosvenorii, fritillaria thunbergii, rhizoma polygonati, Rhizoma Chuanxiong, dried orange peel, almond, melon Beach wormwood, Radix Glehniae, the root bark of Chinese wolf-berry, loquat, fig, radix scrophulariae, ginger, radix saposhnikoviae the tanning time be 45min；The perilla leaf, fish raw meat Grass, campanulaceae, peppermint, bombyx batryticatus, Radix Ophiopogonis, asarum the tanning time be 40min；The tanning of the radix scutellariae, radix aucklandiae, honeysuckle, Fructus Forsythiae Time is 20min.
In the step (1), the poly- propylhomoserin salt includes gamma-polyglutamic acid salt or polyaspartic acid salts；The poly- propylhomoserin The additional amount of salt accounts for the 0.2wt% of each raw material total amount.
In the step (2), further include the steps that freezing gained filtrate before the freeze-drying step.
It is of the present invention treatment pharyngitis pharmaceutical composition, with perilla leaf, Siraitia grosvenorii, fritillaria thunbergii, radix scutellariae, rhizoma polygonati, Rhizoma Chuanxiong, Radix aucklandiae, honeysuckle, cordate houttuynia, Fructus Forsythiae, dried orange peel, campanulaceae, almond, peppermint, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, bombyx batryticatus, loquat, without flower Fruit, Radix Ophiopogonis, radix scrophulariae, asarum, ginger, radix saposhnikoviae are traditional Chinese medicinal components, and using centipede, scorpio and the dried venom of toads as raw material extraction insect protein, The pharmacological property for giving full play to each component, using each ingredient drug effect monarch, minister, help, be allowed between effective cooperation, play altogether its treat pharyngitis it Effect has preferable therapeutic effect to acute, chronic pharyngitis.
Clinical test shows the pharmaceutical composition for the treatment of pharyngitis of the present invention, in the association of traditional Chinese medicinal components and bioprotein Under same-action, there is preferable therapeutic effect for common acute, chronic pharyngitis illness, clinical cure rate is higher, and safe nothing Any toxic side effect.
Specific embodiment
Embodiment 1
The bioprotein liquid for the treatment of pharyngitis described in the present embodiment, bulk pharmaceutical chemicals composition include：Perilla leaf 25kg, Siraitia grosvenorii 35kg, fritillaria thunbergii 20kg, radix scutellariae 8kg, rhizoma polygonati 10kg, Rhizoma Chuanxiong 8kg, radix aucklandiae 4kg, honeysuckle 8kg, cordate houttuynia 4kg, Fructus Forsythiae 15kg, dried orange peel 4kg, campanulaceae 8kg, almond 20kg, peppermint 8kg, Snakegourd Fruit 15kg, Radix Glehniae 15kg, root bark of Chinese wolf-berry 4kg, bombyx batryticatus 35kg, Loquat 4kg, fig 15kg, Radix Ophiopogonis 25kg, radix scrophulariae 15kg, asarum 4kg, ginger 15kg, radix saposhnikoviae 4kg, centipede 0.01kg, scorpio 0.02kg, dried venom of toads 0.0002kg.
The preparation method of the bioprotein liquid for the treatment of pharyngitis described in the present embodiment, includes the following steps：
(1) a selected amount of perilla leaf, Siraitia grosvenorii, fritillaria thunbergii, radix scutellariae, rhizoma polygonati, Rhizoma Chuanxiong, radix aucklandiae, honeysuckle, fish raw meat are taken It is grass, Fructus Forsythiae, dried orange peel, campanulaceae, almond, peppermint, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, bombyx batryticatus, loquat, fig, Radix Ophiopogonis, radix scrophulariae, thin Pungent, ginger, radix saposhnikoviae, and add water to carry out immersion 30-60min respectively；Then by after immersion the Siraitia grosvenorii, fritillaria thunbergii, rhizoma polygonati, Rhizoma Chuanxiong, dried orange peel, almond, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, loquat, fig, radix scrophulariae, ginger, radix saposhnikoviae carry out tanning 45min；It will The perilla leaf, cordate houttuynia, campanulaceae, peppermint, bombyx batryticatus, Radix Ophiopogonis, asarum after immersion carry out tanning 40min；By the institute after immersion It states radix scutellariae, radix aucklandiae, honeysuckle, Fructus Forsythiae and carries out tanning 20min；After filtrate after collecting above-mentioned tanning mixes and is concentrated, and Addition polymerization glutamate (0.2wt% for accounting for all raw material total amounts) and honey 10g are mixed, and obtain Chinese medicine extract, and stablized 48h, it is spare；
(2) a selected amount of centipede, scorpio and the dried venom of toads are taken, after being routinely sieved and removing dust, water is added to extract, from Filtrate is collected after heart 10-30min, 4h is freezed, then carries out freeze-drying 6h, freeze-dried powder is made, and is saved in -30 DEG C, it is spare；
(3) gained Chinese medicine extract and the freeze-dried powder are mixed, customary adjuvant is added, clinic is made according to common process Upper acceptable protein oral liquor, it is filling with 0.016g-0.018g progress under -10 DEG C, relative humidity 5%, closed dim light, Finished product protein oral liquor saves 2-3 at -30 DEG C.
Embodiment 2
The bioprotein liquid for the treatment of pharyngitis described in the present embodiment, bulk pharmaceutical chemicals composition include：Perilla leaf 35kg, Siraitia grosvenorii 25kg, fritillaria thunbergii 30kg, radix scutellariae 4kg, rhizoma polygonati 15kg, Rhizoma Chuanxiong 4kg, radix aucklandiae 8kg, honeysuckle 4kg, cordate houttuynia 8kg, Fructus Forsythiae 10kg, dried orange peel 8kg, campanulaceae 4kg, almond 30kg, peppermint 4kg, Snakegourd Fruit 25kg, Radix Glehniae 10kg, root bark of Chinese wolf-berry 8kg, bombyx batryticatus 25kg, It is loquat 8kg, fig 10kg, Radix Ophiopogonis 35kg, radix scrophulariae 10kg, asarum 8kg, ginger 10kg, radix saposhnikoviae 8kg, centipede 0.005kg, complete Scorpion 0.04kg, dried venom of toads 0.0001kg.
The preparation method of the bioprotein liquid for the treatment of pharyngitis described in the present embodiment, includes the following steps：
(1) a selected amount of perilla leaf, Siraitia grosvenorii, fritillaria thunbergii, radix scutellariae, rhizoma polygonati, Rhizoma Chuanxiong, radix aucklandiae, honeysuckle, fish raw meat are taken It is grass, Fructus Forsythiae, dried orange peel, campanulaceae, almond, peppermint, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, bombyx batryticatus, loquat, fig, Radix Ophiopogonis, radix scrophulariae, thin Pungent, ginger, radix saposhnikoviae, and add water to carry out immersion 30-60min respectively；Then by after immersion the Siraitia grosvenorii, fritillaria thunbergii, rhizoma polygonati, Rhizoma Chuanxiong, dried orange peel, almond, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, loquat, fig, radix scrophulariae, ginger, radix saposhnikoviae carry out tanning 45min；It will The perilla leaf, cordate houttuynia, campanulaceae, peppermint, bombyx batryticatus, Radix Ophiopogonis, asarum after immersion carry out tanning 40min；By the institute after immersion It states radix scutellariae, radix aucklandiae, honeysuckle, Fructus Forsythiae and carries out tanning 20min；After filtrate after collecting above-mentioned tanning mixes and is concentrated, and Addition polymerization glutamate (0.2wt% for accounting for all raw material total amounts) and honey 10g are mixed, and obtain Chinese medicine extract, and stablized 48h, it is spare；
(2) a selected amount of centipede, scorpio and the dried venom of toads are taken, after being routinely sieved and removing dust, water is added to extract, from Filtrate is collected after heart 10-30min, 4h is freezed, then carries out freeze-drying 6h, freeze-dried powder is made, and is saved in -30 DEG C, it is spare；
(3) gained Chinese medicine extract and the freeze-dried powder are mixed, customary adjuvant is added, clinic is made according to common process Upper acceptable protein oral liquor, it is filling with 0.016g-0.018g progress under -10 DEG C, relative humidity 5%, closed dim light, Finished product protein oral liquor saves 2-3 at -30 DEG C.
Embodiment 3
The bioprotein liquid for the treatment of pharyngitis described in the present embodiment, bulk pharmaceutical chemicals composition include：Perilla leaf 30kg, Siraitia grosvenorii 30kg, fritillaria thunbergii 24kg, radix scutellariae 6kg, rhizoma polygonati 12kg, Rhizoma Chuanxiong 6kg, radix aucklandiae 6kg, honeysuckle 6kg, cordate houttuynia 6kg, Fructus Forsythiae 12kg, dried orange peel 6kg, campanulaceae 6kg, almond 24kg, peppermint 6kg, Snakegourd Fruit 20kg, Radix Glehniae 12kg, root bark of Chinese wolf-berry 6kg, bombyx batryticatus 30kg, It is loquat 6kg, fig 12kg, Radix Ophiopogonis 30kg, radix scrophulariae 12kg, asarum 6kg, ginger 12kg, radix saposhnikoviae 6kg, centipede 0.0075kg, complete Scorpion 0.03kg, dried venom of toads 0.00015kg.
The preparation method of the bioprotein liquid for the treatment of pharyngitis described in the present embodiment, includes the following steps：
(1) a selected amount of perilla leaf, Siraitia grosvenorii, fritillaria thunbergii, radix scutellariae, rhizoma polygonati, Rhizoma Chuanxiong, radix aucklandiae, honeysuckle, fish raw meat are taken It is grass, Fructus Forsythiae, dried orange peel, campanulaceae, almond, peppermint, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, bombyx batryticatus, loquat, fig, Radix Ophiopogonis, radix scrophulariae, thin Pungent, ginger, radix saposhnikoviae, and add water to carry out immersion 30-60min respectively；Then by after immersion the Siraitia grosvenorii, fritillaria thunbergii, rhizoma polygonati, Rhizoma Chuanxiong, dried orange peel, almond, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, loquat, fig, radix scrophulariae, ginger, radix saposhnikoviae carry out tanning 45min；It will The perilla leaf, cordate houttuynia, campanulaceae, peppermint, bombyx batryticatus, Radix Ophiopogonis, asarum after immersion carry out tanning 40min；By the institute after immersion It states radix scutellariae, radix aucklandiae, honeysuckle, Fructus Forsythiae and carries out tanning 20min；After filtrate after collecting above-mentioned tanning mixes and is concentrated, and Addition polymerization glutamate (0.2wt% for accounting for all raw material total amounts) and honey 10g are mixed, and obtain Chinese medicine extract, and stablized 48h, it is spare；
(2) a selected amount of centipede, scorpio and the dried venom of toads are taken, after being routinely sieved and removing dust, water is added to extract, from Filtrate is collected after heart 10-30min, 4h is freezed, then carries out freeze-drying 6h, freeze-dried powder is made, and is saved in -30 DEG C, it is spare；
(3) gained Chinese medicine extract and the freeze-dried powder are mixed, customary adjuvant is added, clinic is made according to common process Upper acceptable protein oral liquor, it is filling with 0.016g-0.018g progress under -10 DEG C, relative humidity 5%, closed dim light, Finished product protein oral liquor saves 2-3 at -30 DEG C.
Embodiment 4
The bioprotein liquid for the treatment of pharyngitis described in the present embodiment, bulk pharmaceutical chemicals composition include：Perilla leaf 28kg, Siraitia grosvenorii 32kg, fritillaria thunbergii 22kg, radix scutellariae 7kg, rhizoma polygonati 11kg, Rhizoma Chuanxiong 7kg, radix aucklandiae 5kg, honeysuckle 7kg, cordate houttuynia 5kg, Fructus Forsythiae 14kg, dried orange peel 5kg, campanulaceae 7kg, almond 22kg, peppermint 7kg, Snakegourd Fruit 18kg, Radix Glehniae 14kg, root bark of Chinese wolf-berry 5kg, bombyx batryticatus 32kg, It is loquat 5kg, fig 13kg, Radix Ophiopogonis 28kg, radix scrophulariae 13kg, asarum 5kg, ginger 14kg, radix saposhnikoviae 5kg, centipede 0.009kg, complete Scorpion 0.025kg, dried venom of toads 0.00018kg.
The preparation method is the same as that of Example 1 for the bioprotein liquid for the treatment of pharyngitis described in the present embodiment.
Embodiment 5
The bioprotein liquid for the treatment of pharyngitis described in the present embodiment, bulk pharmaceutical chemicals composition include：Perilla leaf 32kg, Siraitia grosvenorii 28kg, fritillaria thunbergii 27kg, radix scutellariae 5kg, rhizoma polygonati 14kg, Rhizoma Chuanxiong 5kg, radix aucklandiae 7kg, honeysuckle 5kg, cordate houttuynia 7kg, Fructus Forsythiae 11kg, dried orange peel 7kg, campanulaceae 5kg, almond 27kg, peppermint 5kg, Snakegourd Fruit 22kg, Radix Glehniae 11kg, root bark of Chinese wolf-berry 7kg, bombyx batryticatus 28kg, It is loquat 7kg, fig 11kg, Radix Ophiopogonis 32kg, radix scrophulariae 11kg, asarum 7kg, ginger 11kg, radix saposhnikoviae 7kg, centipede 0.0065kg, complete Scorpion 0.035kg, dried venom of toads 0.00012kg.
The preparation method is the same as that of Example 1 for the bioprotein liquid for the treatment of pharyngitis described in the present embodiment.
Experimental example
1, example is treated
Clinic collects 90 patients for being diagnosed as pharyngitis, wherein is diagnosed as patient 38 of acpuei pharyngitis, chronic pharyngitis Patient 52；Male, female patient's number are approximate in patient.
Acpuei pharyngitis patient is mainly shown as that pharyngalgia, state of an illness severe one have the diseases such as dysphagia and aversion to cold, fever；Through pharyngeal inspection It looks into, mucous hyperemia, swelling is presented in patient, and lateral pharyngeal band is red and swollen, swallows rear wall lymph foilicie hyperplasia；Onset is more anxious, and most courses of disease are shorter.
Patients with chronic pharyngitis is mainly shown as daily pharyngeal drying, or itches, aches, foreign body sensation, the symptoms such as swelling sense；Most diseases Journey is longer, weight when pharyngeal discomfort symptom is light；Often have acute throat obstruction history of repeated attack, or because of chronic rhinitis long-term mouth breathing or because Excessive drinking and smoking, surrounding air are dry, dust different gas stimulation etc. causes to fall ill；Pharyngeal inspection mucous membrane swelling has atrophy or has dark Rear wall lymph foilicie hyperplasia is swallowed in red grouper bulk, dendroid congested, lateral pharyngeal band enlargement.
2 bottles of the protein oral liquor is made in above-mentioned patient daily take in embodiment 3, continuously take that 7 days as a course for the treatment of, Different patients take the 2-5 course for the treatment of, are taken most preferably with half an hour before meals.Actual therapeutic effect see the table below 1.
According to《Chinese medical disease Standardization of diagnosis and curative effect》Judgement：
It cures：Pharyngeal symptom disappears, and the symptoms such as pharyngalgia, fever disappear, and pharyngeal inspection restores normal；
It is effective：Pharyngeal sings and symptoms are substantially reduced, pharyngalgia and pharyngeal swelling are substantially reduced；
In vain：Pharyngeal sings and symptoms are without significant change.
1 actual therapeutic effect of table
Illness Healing/example Effective/example In vain/example Whole effective percentage/%
Acpuei pharyngitis 36 2 0 96.2%
Chronic pharyngitis 48 2 2 100%
It can see from above-mentioned data, protein oral liquor of the present invention has the diseases such as acute/chronic pharyngitis patient preferable Therapeutic effect, overall efficiency is higher.
Two, typical case
1, patient pacifies so-and-so, male, and 35 years old, daily pharyngeal discomfort, drying were up to 2-3, often has foreign body sensation, and feel even There is dysphagia, it is pharyngeal to have mucous membrane swelling symptom through clinical medicine inspection, also see contrafluxion state, clinical diagnosis is chronic Pharyngitis.
It is daily to take protein oral liquor in the embodiment of the present invention 3, daily two bottles, after taking January, throat discomfort and xerosis Shape disappears substantially, and breathing is completely normal；And with sight 6 months without recurrence.
2, patient's Mr. Lin, female 25 years old, feel abscess of throat after influenza, dysphagia and heating paresthesia occur, through pharyngeal inspection It looks into, mucous hyperemia is presented and swelling, clinical diagnosis are acpuei pharyngitis.
It is daily to take protein oral liquor in the embodiment of the present invention 3, daily two bottles, after taking 1 week, through medical inspection, throat Swelling state disappears, and feeling of pain disappears, with sight 1 month without recurrence.
3, patient's temperature, male 56 years old, suffer from many years chronic pharyngitis, and the daily Caoshan Hu Hanpian that fully relies on alleviates throat not It is suitable, but symptom does not disappear or fully recovers.
Daily to take protein oral liquor in the embodiment of the present invention 3, daily two bottles, after taking January, throat discomfort disappears completely It loses, without taking Caoshan Hu Hanpian, pain symptom is completely disappeared.
4, patient Chen, male, 38 years old, happened suddenly acpuei pharyngitis, and abscess of throat is serious, daily to take the embodiment of the present invention 3 Middle protein oral liquor, daily two bottles, after taking 1 day, symptom of having sore throat is relieved, after taking 3 days, throat discomfort symptom It completely disappears.
5, patient relaxes so-and-so, female, and 55 years old, the patient body immunity was poor, with chronic pharyngitis for many years be not cured, day informal dress It with protein oral liquor in the embodiment of the present invention 3, daily two bottles, takes after half a month, throat discomfort symptom substantially improves, and continues to take When to one month, symptom is completely disappeared, and clinical medicine check it is pharyngeal completely normal, with seeing 6 months without recurrence and side effect.
6, patient it is pungent certain, male, 39 years old, clinical diagnosis suffer from acpuei pharyngitis, take antibiotic 3 days to no effect, after drug withdrawal, day Informal dress protein oral liquor in the embodiment of the present invention 3, daily two bottles, after taking March, pharyngeal discomfort symptom disappears substantially, clinical Diagnosis is cured.
Obviously, the above embodiments are merely examples for clarifying the description, and does not limit the embodiments.It is right For those of ordinary skill in the art, can also make on the basis of the above description it is other it is various forms of variation or It changes.There is no necessity and possibility to exhaust all the enbodiments.And it is extended from this it is obvious variation or It changes still within the protection scope of the invention.

Claims (10)

1. a kind of pharmaceutical composition for treating pharyngitis, which is characterized in that the bulk pharmaceutical chemicals of described pharmaceutical composition, which form, includes：Purple perilla Leaf 25-35 parts by weight, Siraitia grosvenorii 25-35 parts by weight, fritillaria thunbergii 20-30 parts by weight, radix scutellariae 4-8 parts by weight, rhizoma polygonati 10-15 weight Part, Rhizoma Chuanxiong 4-8 parts by weight, radix aucklandiae 4-8 parts by weight, honeysuckle 4-8 parts by weight, cordate houttuynia 4-8 parts by weight, Fructus Forsythiae 10-15 weight Part, dried orange peel 4-8 parts by weight, campanulaceae 4-8 parts by weight, almond 20-30 parts by weight, peppermint 4-8 parts by weight, Snakegourd Fruit 15-25 parts by weight, Radix Glehniae 10-15 parts by weight, root bark of Chinese wolf-berry 4-8 parts by weight, bombyx batryticatus 25-35 parts by weight, loquat 4-8 parts by weight, fig 10-15 weight Measure part, Radix Ophiopogonis 25-35 parts by weight, radix scrophulariae 10-15 parts by weight, asarum 4-8 parts by weight, ginger 10-15 parts by weight, radix saposhnikoviae 4-8 weight Measure part, centipede 0.005-0.01 parts by weight, scorpio 0.02-0.04 parts by weight, dried venom of toads 0.0001-0.0002 parts by weight.
2. the pharmaceutical composition for the treatment of pharyngitis according to claim 1, which is characterized in that the raw material of described pharmaceutical composition Medicine forms：30 parts by weight of perilla leaf, 30 parts by weight of Siraitia grosvenorii, 24 parts by weight of fritillaria thunbergii, 6 parts by weight of radix scutellariae, 12 weight of rhizoma polygonati Measure part, 6 parts by weight of Rhizoma Chuanxiong, 6 parts by weight of radix aucklandiae, 6 parts by weight of honeysuckle, 6 parts by weight of cordate houttuynia, 12 parts by weight of Fructus Forsythiae, 6 weight of dried orange peel Measure part, 6 parts by weight of campanulaceae, 24 parts by weight of almond, 6 parts by weight of peppermint, 20 parts by weight of Snakegourd Fruit, 12 parts by weight of Radix Glehniae, the root bark of Chinese wolf-berry 6 Parts by weight, 30 parts by weight of bombyx batryticatus, 6 parts by weight of loquat, 12 parts by weight of fig, 30 parts by weight of Radix Ophiopogonis, 12 parts by weight of radix scrophulariae, asarum 6 parts by weight, 12 parts by weight of ginger, windproof 6 parts by weight, 0.0075 parts by weight of centipede, 0.03 parts by weight of scorpio, the dried venom of toads 0.00015 Parts by weight.
3. the purposes that pharmaceutical composition of any of claims 1 or 2 is used to prepare the pharmaceutical preparation for the treatment of pharyngitis.
4. customary adjuvant is added by pharmaceutical composition of any of claims 1 or 2, it is acceptable according to clinic made of common process Treatment pharyngitis pharmaceutical preparation.
5. pharmaceutical preparation according to claim 4, which is characterized in that the pharmaceutical preparation includes oral solution, capsule, piece Agent.
6. a kind of method for the pharmaceutical preparation for preparing the treatment pharyngitis of claim 4 or 5, which is characterized in that including walking as follows Suddenly：
(1) take a selected amount of perilla leaf, Siraitia grosvenorii, fritillaria thunbergii, radix scutellariae, rhizoma polygonati, Rhizoma Chuanxiong, radix aucklandiae, honeysuckle, cordate houttuynia, Fructus Forsythiae, dried orange peel, campanulaceae, almond, peppermint, Snakegourd Fruit, Radix Glehniae, the root bark of Chinese wolf-berry, bombyx batryticatus, loquat, fig, Radix Ophiopogonis, radix scrophulariae, asarum, Ginger, radix saposhnikoviae, and add water to be impregnated and boiled respectively, after collecting filtrate and being concentrated, poly- propylhomoserin salt is added and honey mixes, obtains It is spare to Chinese medical extract；
(2) a selected amount of centipede, scorpio and the dried venom of toads are taken, water is added to extract, after collecting filtrate and being freeze-dried, is made and freezes Dry powder, it is spare；
(3) gained Chinese medical extract and the freeze-dried powder are mixed, customary adjuvant is added, points out clinically may be used according to common process The preparation of receiving.
7. the method for the pharmaceutical preparation according to claim 6 for preparing the treatment pharyngitis, which is characterized in that the step (1) in, the soaking step time is 30-60min.
8. the method for the pharmaceutical preparation according to claim 6 or 7 for preparing the treatment pharyngitis, which is characterized in that described In step (1), in the tanning step, the Siraitia grosvenorii, fritillaria thunbergii, rhizoma polygonati, Rhizoma Chuanxiong, dried orange peel, almond, Snakegourd Fruit, Radix Glehniae, Bone skin, loquat, fig, radix scrophulariae, ginger, radix saposhnikoviae the tanning time be 45min；The perilla leaf, cordate houttuynia, campanulaceae, peppermint, Bombyx batryticatus, Radix Ophiopogonis, asarum the tanning time be 40min；The radix scutellariae, radix aucklandiae, honeysuckle, Fructus Forsythiae the tanning time be 20min.
9. according to the method for the described in any item pharmaceutical preparations for preparing the treatment pharyngitis of claim 6-8, which is characterized in that In the step (1), the poly- propylhomoserin salt includes gamma-polyglutamic acid salt or polyaspartic acid salts；The addition of the poly- propylhomoserin salt Amount accounts for the 0.2wt% of each raw material total amount.
10. according to the method for the described in any item pharmaceutical preparations for preparing the treatment pharyngitis of claim 6-9, feature exists In further including the steps that freezing gained filtrate before the freeze-drying step in the step (2).
CN201811073967.7A 2018-09-14 2018-09-14 A kind of pharmaceutical composition and the preparation method and application thereof for treating pharyngitis Pending CN108815498A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201811073967.7A CN108815498A (en) 2018-09-14 2018-09-14 A kind of pharmaceutical composition and the preparation method and application thereof for treating pharyngitis

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201811073967.7A CN108815498A (en) 2018-09-14 2018-09-14 A kind of pharmaceutical composition and the preparation method and application thereof for treating pharyngitis

Publications (1)

Publication Number Publication Date
CN108815498A true CN108815498A (en) 2018-11-16

Family

ID=64149842

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201811073967.7A Pending CN108815498A (en) 2018-09-14 2018-09-14 A kind of pharmaceutical composition and the preparation method and application thereof for treating pharyngitis

Country Status (1)

Country Link
CN (1) CN108815498A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109224060A (en) * 2018-11-30 2019-01-18 中商国能孵化器集团有限公司 A kind of pharmaceutical composition and the preparation method and application thereof for treating rhinitis

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03167132A (en) * 1989-11-28 1991-07-19 Lotte Co Ltd Composition for buccal cavity
CN101274092A (en) * 2008-04-22 2008-10-01 梁进 Paste for clearing away the lung-heat and relieving cough
CN103330886A (en) * 2013-06-27 2013-10-02 柳晖 Traditional Chinese medicine composition for treating chronic pharyngitis
CN105963533A (en) * 2016-07-12 2016-09-28 杨高林 Preparation method of traditional Chinese medicine for treating chronic pharyngitis and traditional Chinese medicine buccal tablet
CN108030910A (en) * 2018-02-09 2018-05-15 王中杰 For treating the Chinese prescription of pharyngitis

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH03167132A (en) * 1989-11-28 1991-07-19 Lotte Co Ltd Composition for buccal cavity
CN101274092A (en) * 2008-04-22 2008-10-01 梁进 Paste for clearing away the lung-heat and relieving cough
CN103330886A (en) * 2013-06-27 2013-10-02 柳晖 Traditional Chinese medicine composition for treating chronic pharyngitis
CN105963533A (en) * 2016-07-12 2016-09-28 杨高林 Preparation method of traditional Chinese medicine for treating chronic pharyngitis and traditional Chinese medicine buccal tablet
CN108030910A (en) * 2018-02-09 2018-05-15 王中杰 For treating the Chinese prescription of pharyngitis

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109224060A (en) * 2018-11-30 2019-01-18 中商国能孵化器集团有限公司 A kind of pharmaceutical composition and the preparation method and application thereof for treating rhinitis

Similar Documents

Publication Publication Date Title
CN105012392A (en) Traditional Chinese medicine composition for treating rhinitis and preparation method thereof
CN106138360A (en) A kind of Chinese medicine composition and preparation method thereof, application
CN102688347B (en) Traditional Chinese medicine preparation for treating oral inflammation and preparation method thereof
CN102579701A (en) Compound dandelion decoction
WO2020155318A1 (en) Traditional chinese medicine preparation for treatment of bacterial respiratory tract disease in livestock and production technique thereof
CN104523952A (en) Chinese herbal medicine composition for treating chicken influenza
CN108815498A (en) A kind of pharmaceutical composition and the preparation method and application thereof for treating pharyngitis
CN106729482A (en) A kind of selenium-rich snow pear paste with alleviation asthma Effects
CN104288477A (en) Traditional Chinese medicine preparation curing infantile asthma
CN104189605B (en) Traditional Chinese preparation for treating acute nasopharyngitis and preparation method thereof
CN103446564B (en) Chinese medicine composition of a kind of anti-inflammation and preparation method thereof
CN103719616B (en) Feed for treating bloody flux of pigs and preparation method of feed
CN105327103A (en) Medicine composition for treating rhinitis and nasosinusitis and preparation method of medicine composition
CN104758530A (en) Traditional Chinese medicine composition for treating deficiency of both qi and blood type irregular menstruation
CN105125994A (en) Traditional Chinese medicine for treating oral ulcer
CN104587035B (en) Medicine composition for treating oral ulcer and preparation method for medicine composition
CN104257777B (en) Traditional Chinese medicine composition for treating rhinitis, nasosinusitis and frontal sinusitis and preparation method of traditional Chinese medicine composition
CN115300544B (en) Traditional Chinese medicine composition and patch for dispelling wind, relieving exterior syndrome, detumescence and inducing resuscitation and preparation method thereof
CN109091633B (en) Composition for treating recurrent respiratory tract infection of children and preparation method and application thereof
CN104826072A (en) Traditional Chinese medicine preparation for treating respiratory system infection and preparation method of traditional Chinese medicine preparation
CN104873606A (en) Traditional Chinese medicine external used agent for curing ulcerative gingivitis and preparation method thereof
CN104491331B (en) A kind of pharmaceutical composition with antitussive action
CN104189815A (en) Traditional Chinese medicine preparation for treating children bronchial asthma
CN103735919B (en) Medicine being used for the treatment of swine influenza and preparation method thereof
CN111514215A (en) Traditional Chinese medicine prescription for treating upper respiratory tract infection and viral pneumonia and application

Legal Events

Date Code Title Description
PB01 Publication
PB01 Publication
SE01 Entry into force of request for substantive examination
SE01 Entry into force of request for substantive examination
RJ01 Rejection of invention patent application after publication
RJ01 Rejection of invention patent application after publication

Application publication date: 20181116